Take Akira 武晃

Researcher Number	30818399
Other IDs
Affiliation (Current)	2024: 北里大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 北里大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 49050:Bacteriology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 49050:Bacteriology-related
Keywords	Principal Investigator 肝性脳症 / Streptococcus salivarius / LC/MS / Clostridioides difficile / 溶菌酵素 / バクテリオファージ / ペプチドグリカン / 細胞壁 / C. difficile / C. difficile感染症 … More Except Principal Investigator … More アルコール性肝障害 / 抗血小板抗体 / 宿主認識機構 / 腸内細菌叢 / 予防 / 治療 / 腸内フローラ / 尾部吸着分子 / 宿主特異性 / バクテリオファージ / C. difficile感染症 / Clostridioides difficile Less

アルコール性肝障害に伴う血小板減少に関する抗血小板抗体の病因的意義の解明
- Principal Investigator
  
  日高央
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kitasato University
Investigation of the mechanism of hepatic encephalopathy caused by oral streptococciPrincipal Investigator
- Principal Investigator
  
  武晃
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kitasato University
Study for the host recognition mechanism of bacteriophage tail adsorption molecules in Clostridioides difficile
- Principal Investigator
  
  阪口義彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Tokushima Bunri University
  Kitasato University
Structural analysis of the cell wall of Clostridioides difficile using lytic enzyme of bacteriophagePrincipal Investigator
- Principal Investigator
  
  Take Akira
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kitasato University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Complete match of Streptococcus salivarius from oral saliva and stool in a patient with hepatic encephalopathy2024
- Author(s)
  Nomura Nao、Take Akira、Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Horio Kazue、Mizokami Masashi、Hayashi Shunji、Kusano Chika
- Journal Title
  
  Internal Medicine
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07074
[Journal Article] Clostridium perfringens epsilon-toxin requires acid sphingomyelinase for cellular entry2023
- Author(s)
  Sakaguchi Yoshihiko、Kobayashi Keiko、Takehara Masaya、Nagahama Masahiro
- Journal Title
  
  Anaerobe
  
  Volume: 82 Pages: 102753-102753
- DOI
  10.1016/j.anaerobe.2023.102753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07074
[Journal Article] Impact of body composition for patients with hepatocellular carcinoma who received atezolizumab plus bevacizumab therapy2023
- Author(s)
  Uojima, H., Chuma, M., Hidaka, H., Tsuda, T., Kobayashi, S., Hattori, N., Ogushi, K., Arase, Y., Take, A, Sakaguchi, Y., Ando, T., Nishigori, S., Watanbe, T., Numata, K., Morimoto, M., Kagawa, T., Kako, M., Kusano, C.
- Journal Title
  
  Eur. J. Gastroenterol. Hepatol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07074
[Journal Article] Impact of liver fibrosis on the relative abundance of a urease‐positive <i>Streptococcus salivarius</i> group from saliva in patients with chronic liver disease2023
- Author(s)
  Tak Akira、Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Horio Kazue、Mizokami Masashi、Hayashi Shunji、Kusano Chika
- Journal Title
  
  Hepatology Research
  
  Volume: 53 Issue: 10 Pages: 998-1007
- DOI
  10.1111/hepr.13930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15083, KAKENHI-PROJECT-22K07074
[Journal Article] Cellular Uptake and Cytotoxicity of Clostridium perfringens Iota-Toxin2023
- Author(s)
  Nagahama Masahiro、Takehara Masaya、Seike Soshi、Sakaguchi Yoshihiko
- Journal Title
  
  Toxins
  
  Volume: 15 Issue: 12 Pages: 695-695
- DOI
  10.3390/toxins15120695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-22K07081
[Journal Article] Metabolic Dysfunction-Associated Fatty Liver Disease on Distinct Microbial Communities at the Bacterial Phylum Level2023
- Author(s)
  Uojima Haruki、Sakaguchi Yoshihiko、Gotoh Kazuyoshi、Satoh Takashi、Hidaka Hisashi、Take Akira、Horio Kazue、Hayashi Shunji、Kusano Chika
- Journal Title
  
  Digestive Diseases
  
  Volume: 42 Issue: 1 Pages: 61-69
- DOI
  10.1159/000534284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15083, KAKENHI-PROJECT-22K07074
[Journal Article] Fecal microbiota transplantation as therapy for recurrent Clostridioides difficile infection is associated with amelioration of delirium and accompanied by changes in fecal microbiota and the metabolome2022
- Author(s)
  Gotoh Kazuyoshi、Sakaguchi Yoshihiko、Kato Haru、Osaki Hayato、Jodai Yasutaka、Wakuda Mitsutaka、Take Akira、Hayashi Shunji、Morita Eri、Sugie Takehiko、Ito Yoichiro、Ohmiya Naoki
- Journal Title
  
  Anaerobe
  
  Volume: 73 Pages: 102502-102502
- DOI
  10.1016/j.anaerobe.2021.102502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07560, KAKENHI-PROJECT-20K16250, KAKENHI-PROJECT-22K07074
[Journal Article] Phylogenic analysis of new viral cluster of large phages with unusual DNA genomes containing uracil in place of thymine in gene-sharing network, using phages S6 and PBS1 and relevant uncultured phages derived from sewage metagenomics2022
- Author(s)
  Uchiyama, J., Takemura-Uchiyama, I., Gotoh, K., Kato, S., Sakaguchi, Y., Murakami, H., Fukuyama, T., Kaneki, M., Matsushita, O., Matsuzaki, S.
- Journal Title
  
  Virus Res.
  
  Volume: 319 Pages: 198881-198881
- DOI
  10.1016/j.virusres.2022.198881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-22K08580, KAKENHI-PROJECT-22K08593
[Journal Article] Evaluation of skeletal muscle mass in patients with chronic liver disease shows different results based on bioelectric impedance analysis and computed tomography2022
- Author(s)
  Kikuchi, N., Uojima, H., Hidaka, H., Iwasaki, S., Wada, N., Kubota, K., Nakazawa, T., Shibuya, A., Kako, M., Take, A., Sakaguchi, Y., Sato, T., Kusano, C.
- Journal Title
  
  Ann. Nutr. Metab.
  
  Volume: 78(6) Issue: 6 Pages: 336-344
- DOI
  10.1159/000526563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07074
[Journal Article] The change rate in serum nitric oxide may affect lenvatinib therapy in hepatocellular carcinoma.2022
- Author(s)
  Kawamura A, Uojima H, Chuma M, Shao X, Hidaka H, Nakazawa T, Take A, Sakaguchi Y, Numata K, Kako M, Nozaki A, Azuma S, Horio K, Kusano C, Atsuda K
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 912-921
- DOI
  10.1186/s12885-022-10002-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07899, KAKENHI-PROJECT-22K07074
[Journal Article] Antibiotic-resistant status and pathogenic clonal complex of canine Streptococcus canis-associated deep pyoderma2022
- Author(s)
  Imanishi, I., Iyori, K., Take, A., Asahina, R., Tsunoi, M., Hirano, R., Uchiyama, J., Toyoda, Y., Sakaguchi, Y., Hayashi, S.
- Journal Title
  
  BMC Vet. Res.
  
  Volume: 18(1) Issue: 1 Pages: 395-395
- DOI
  10.1186/s12917-022-03482-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-22K08580
[Journal Article] Analysis of a plasmid encoding botulinum neurotoxin type G gene in Clostridium argentinense2020
- Author(s)
  Sakaguchi, Y., Uchiyama, J., Take, A., Gotoh, K., Sakaguchi, M., Suzuki, T., Yamamoto, Y., Hosomi, K., Kohda, T., Mukamoto, M., Kozaki, S., Hayashi, S., Oguma, K.
- Journal Title
  
  Anaerobe
  
  Volume: 66 Pages: 102281-102281
- DOI
  10.1016/j.anaerobe.2020.102281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07560, KAKENHI-PROJECT-20K16250, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K07127, KAKENHI-PROJECT-16H06277
[Presentation] 再発性Clostridioides difficile感染症に対する糞便微生物移植療法から見出した腸内放線菌の生理活性評価2024
- Author(s)
  阪口義彦、武　晃、後藤和義、友信奈保子、山本健一、竹原正也、塩見慎也、吉田昌裕、久保美和、野路征昭、和久田光毅、阪口政清、加藤はる、大宮直木、永浜政博
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] 農作物および肥料からの放線菌の分離と分類2023
- Author(s)
  武　晃、阪口義彦、稲橋佑起、後藤和義、林俊治
- Organizer
  第37回日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] 糞便微生物移植治療から見出した腸内の放線菌の生理活性評価2023
- Author(s)
  阪口義彦、武　晃、後藤和義、竹原正也、友信奈保子、山本健一、菊池雄太、坂本光央、加藤はる、大宮直木、阪口政清、永浜政博
- Organizer
  日本組織培養学会第95回大会
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] C型とD型ボツリヌス毒素をコードするバクテリオファージの解析2023
- Author(s)
  阪口義彦、武　晃、後藤和義、山本　由弥子、幸田知子、竹原正也、向本雅郁、小崎俊司、林　哲也、小熊惠二、永浜政博
- Organizer
  第76回日本細菌学会中国・四国支部総会
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] C型とD型ボツリヌス毒素をコードするバクテリオファージのゲノム比較解析2023
- Author(s)
  阪口義彦、武　晃、後藤和義、山本由弥子、幸田知子、向本雅郁、小崎俊司、林　俊治、林哲也、小熊惠二
- Organizer
  第96回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] ヒト糞便検体からの放線菌の分離とその生物活性評価2023
- Author(s)
  武　晃、阪口義彦、菊池雄太、稲橋佑起、後藤和義、林　俊治、坂本光央、大宮直木
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] 食物およびヒト糞便から分離した放線菌の人工消化液での生残性2022
- Author(s)
  武晃, 阪口義彦, 稲橋佑起, 後藤和義, 林俊治, 加藤はる, 大宮直木
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K16250
[Presentation] C型とD型ボツリヌス毒素を支配するバクテリオファージの溶原化機構の解析2022
- Author(s)
  阪口義彦, 武晃, 後藤和義, 山本由弥子, 幸田知子, 向本雅郁, 小崎俊司, 林俊治, 林哲也, 小熊惠二
- Organizer
  第95回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16250
[Presentation] ヒト糞便検体からの放線菌の分離とその代謝産物解析2022
- Author(s)
  武　晃、阪口義彦、菊池雄太、稲橋佑起、後藤和義、坂本光央、林　俊治
- Organizer
  2022年度（第36回）日本放線菌学会大会
- Data Source
  KAKENHI-PROJECT-22K07074
[Presentation] Clostridioides difficile 感染症に対する糞便微生物移植の影響～ヒト腸内微生物叢及びメタボロームの解析～2021
- Author(s)
  阪口義彦, 後藤和義, 武晃, 尾﨑隼人, 城代康貴, 和久田光毅, 林俊治, 大宮直木, 加藤はる
- Organizer
  第94回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16250
[Presentation] 食物から分離した放線菌の腸内環境生存能の評価2021
- Author(s)
  武晃, 阪口義彦, 稲橋佑起, 後藤和義, 林俊治, 大宮直木, 加藤はる
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K16250
[Presentation] Clostridioides difficile 感染症に対する糞便微生物移植の影響～ヒト腸内微生物叢及びメタボロームの解析～2021
- Author(s)
  阪口義彦，後藤和義，武晃，尾﨑隼人，城代康貴，和久田光毅，林俊治，大宮直木，加藤はる
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K16250
[Presentation] 食物から分離した放線菌の腸内環境生存能の評価2021
- Author(s)
  武晃，阪口義彦，稲橋佑起，後藤和義，林俊治，大宮直木，加藤はる
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K16250

1. 阪口義彦 (70403491)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. 後藤和義 (20626593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. 大宮直木 (00335035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 日高央 (30265607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 魚嶋晴紀 (20752869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 朝倉崇文 (30596466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤隆司 (90407114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UCHIYAMA Jumpei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. CHUMA Makoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 林俊治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 加藤はる

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Take Akira 武 晃

Research Projects

Research Products

Co-Researchers

アルコール性肝障害に伴う血小板減少に関する抗血小板抗体の病因的意義の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the mechanism of hepatic encephalopathy caused by oral streptococciPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for the host recognition mechanism of bacteriophage tail adsorption molecules in Clostridioides difficile

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of the cell wall of Clostridioides difficile using lytic enzyme of bacteriophagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Complete match of Streptococcus salivarius from oral saliva and stool in a patient with hepatic encephalopathy2024

Author(s)

Journal Title

Data Source

[Journal Article] Clostridium perfringens epsilon-toxin requires acid sphingomyelinase for cellular entry2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of body composition for patients with hepatocellular carcinoma who received atezolizumab plus bevacizumab therapy2023

Author(s)

Journal Title

Data Source

[Journal Article] Impact of liver fibrosis on the relative abundance of a urease‐positive <i>Streptococcus salivarius</i> group from saliva in patients with chronic liver disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular Uptake and Cytotoxicity of Clostridium perfringens Iota-Toxin2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic Dysfunction-Associated Fatty Liver Disease on Distinct Microbial Communities at the Bacterial Phylum Level2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fecal microbiota transplantation as therapy for recurrent Clostridioides difficile infection is associated with amelioration of delirium and accompanied by changes in fecal microbiota and the metabolome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phylogenic analysis of new viral cluster of large phages with unusual DNA genomes containing uracil in place of thymine in gene-sharing network, using phages S6 and PBS1 and relevant uncultured phages derived from sewage metagenomics2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of skeletal muscle mass in patients with chronic liver disease shows different results based on bioelectric impedance analysis and computed tomography2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The change rate in serum nitric oxide may affect lenvatinib therapy in hepatocellular carcinoma.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibiotic-resistant status and pathogenic clonal complex of canine Streptococcus canis-associated deep pyoderma2022

Author(s)

Journal Title

DOI

Take Akira 武晃

[Presentation] Clostridioides difficile 感染症に対する糞便微生物移植の影響～ヒト腸内微生物叢及びメタボロームの解析～2021

[Presentation] Clostridioides difficile 感染症に対する糞便微生物移植の影響～ヒト腸内微生物叢及びメタボロームの解析～2021