Sase Kana 佐瀬佳奈

Researcher Number	30821904
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 聖マリアンナ医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator p62 / ｐ62 / オートファジー / 抗酸化 / Nrf2 / 抗酸化作用 / MAPKｐ38 / 視神経軸索保護 / ｐ38 / 軸索保護 / p38 / p-p38

p62を中心とした視神経軸索障害におけるオートファジーと抗酸化経路の相互機構解明Principal Investigator
- Principal Investigator
  
  佐瀬佳奈
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  St. Marianna University School of Medicine
Elucidation of optic nerve protection via inhibition of p38-p62 signalPrincipal Investigator
- Principal Investigator
  
  Sase Kana
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  St. Marianna University School of Medicine

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Inhibition of p38 ameliorates axonal loss with modulation of autophagy in TNF-induced optic nerve damage2023
- Author(s)
  Sase K, Tsukahara C, Fujita N, Arizono I, Otsubo M, Kitaoka Y
- Journal Title
  
  Int Ophthalmol
  
  Volume: in press Issue: 9 Pages: 3067-3074
- DOI
  10.1007/s10792-023-02706-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09843, KAKENHI-PROJECT-19K18894
[Journal Article] 病因別血管新生緑内障に対する線維柱帯切除術の長期成績2022
- Author(s)
  上杉康雄, 徳田直人, 山田雄介, 豊田泰大, 塚本彩香, 塚原千広, 佐瀬佳奈, 北岡康史, 高木均
- Journal Title
  
  あたらしい眼科
  
  Volume: 39 Pages: 354-357
- Data Source
  KAKENHI-PROJECT-19K18894
[Journal Article] Axonal Protection by Netarsudil, a ROCK Inhibitor, Is Linked to an AMPK-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration2022
- Author(s)
  Kitaoka Y, Sase K, Tsukahara C, Fujita N, Arizono I, Kogo J, Tokuda N, Takagi H.
- Journal Title
  
  Invest Ophthalmol Vis Sci .
  
  Volume: 63 Issue: 1 Pages: 4-4
- DOI
  10.1167/iovs.63.1.4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09837, KAKENHI-PROJECT-19K18894
[Journal Article] Akebia Saponin D prevents axonal loss against TNF-induced optic nerve damage with autophagy modulation2020
- Author(s)
  Sase Kana、Tsukahara Chihiro、Fujita Naoki、Arizono Ibuki、Takagi Hitoshi、Kitaoka Yasushi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 47 Issue: 12 Pages: 9733-9738
- DOI
  10.1007/s11033-020-06008-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09837, KAKENHI-PROJECT-19K18894, KAKENHI-PROJECT-18K09427
[Journal Article] Axonal Protection by Nicotinamide Riboside via SIRT1-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration2020
- Author(s)
  Kitaoka Yasushi、Sase Kana、Tsukahara Chihiro、Fujita Naoki、Arizono Ibuki、Takagi Hitoshi
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 57 Issue: 12 Pages: 4952-4960
- DOI
  10.1007/s12035-020-02063-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09837, KAKENHI-PROJECT-19K18894, KAKENHI-PROJECT-18K09427
[Journal Article] Pemafibrate prevents retinal neuronal cell death in NMDA-induced excitotoxicity via inhibition of p-c-Jun expression2020
- Author(s)
  Fujita Naoki、Sase Kana、Tsukahara Chihiro、Arizono Ibuki、Takagi Hitoshi、Kitaoka Yasushi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 48 Issue: 1 Pages: 195-202
- DOI
  10.1007/s11033-020-06032-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09837, KAKENHI-PROJECT-19K18894, KAKENHI-PROJECT-18K09427
[Presentation] TNF誘発視神経障害モデルにおけるp38阻害剤の保護作用2022
- Author(s)
  佐瀬佳奈、塚原千広、藤田直樹、有薗生吹、北岡康史
- Organizer
  第33回日本緑内障学会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] TNF誘発視神経障害モデルにおけるp38阻害剤の視神経軸索保護作用2021
- Author(s)
  佐瀬佳奈、塚原千広、藤田直輝、有薗生吹、高木　均、北岡康史
- Organizer
  第40回　日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] 網膜神経節細胞障害モデルラットに対するペマフィブラート内服による神経保護効果2021
- Author(s)
  藤田直輝, 塚原千広, 佐瀬佳奈, 北岡康史, 高木　均
- Organizer
  第13回神奈川眼科学会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] TNF誘発視神経障害モデルにおけるNFATｃ阻害剤の軸索保護効果とIＬ-1β2021
- Author(s)
  塚原千広, 佐瀬佳奈, 藤田直輝, 有薗生吹, 高木　均, 北岡康史
- Organizer
  第41回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] AMPKとTNF視神経障害モデル2021
- Author(s)
  北岡康史, 塚原千広, 佐瀬佳奈, 藤田直輝, 有薗生吹, 高木　均
- Organizer
  第41回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] 高眼圧モデルにおけるnicotinamide riboside（NR）による軸索保護効果2021
- Author(s)
  有薗生吹, 藤田直輝, 塚原千広, 佐瀬佳奈, 高木　均, 北岡康史
- Organizer
  第41回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] 網膜神経節細胞の蛋白発現異常と緑内障病態2020
- Author(s)
  佐瀬佳奈
- Organizer
  第31回日本緑内障学会シンポジウム3　緑内障の細胞機能異常と治療
- Invited
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] MAPKp38シグナル抑制による視神経軸索保護作用とオートファジー2019
- Author(s)
  佐瀬　佳奈
- Organizer
  第123回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-19K18894
[Presentation] TNF誘発視神経障害モデルに対するオートファジーとMAPKｐ-ｐ38の関与2019
- Author(s)
  佐瀬　佳奈
- Organizer
  第39回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-19K18894

1. 高木均

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 北岡康史

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Sase Kana 佐瀬 佳奈

Research Projects

Research Products

Co-Researchers

p62を中心とした視神経軸索障害におけるオートファジーと抗酸化経路の相互機構解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of optic nerve protection via inhibition of p38-p62 signalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Inhibition of p38 ameliorates axonal loss with modulation of autophagy in TNF-induced optic nerve damage2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 病因別血管新生緑内障に対する線維柱帯切除術の長期成績2022

Author(s)

Journal Title

Data Source

[Journal Article] Axonal Protection by Netarsudil, a ROCK Inhibitor, Is Linked to an AMPK-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Akebia Saponin D prevents axonal loss against TNF-induced optic nerve damage with autophagy modulation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Axonal Protection by Nicotinamide Riboside via SIRT1-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pemafibrate prevents retinal neuronal cell death in NMDA-induced excitotoxicity via inhibition of p-c-Jun expression2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] TNF誘発視神経障害モデルにおけるp38阻害剤の保護作用2022

Author(s)

Organizer

Data Source

[Presentation] TNF誘発視神経障害モデルにおけるp38阻害剤の視神経軸索保護作用2021

Author(s)

Organizer

Data Source

[Presentation] 網膜神経節細胞障害モデルラットに対するペマフィブラート内服による神経保護効果2021

Author(s)

Organizer

Data Source

[Presentation] TNF誘発視神経障害モデルにおけるNFATｃ阻害剤の軸索保護効果とIＬ-1β2021

Author(s)

Organizer

Data Source

[Presentation] AMPKとTNF視神経障害モデル2021

Author(s)

Organizer

Data Source

[Presentation] 高眼圧モデルにおけるnicotinamide riboside（NR）による軸索保護効果2021

Author(s)

Organizer

Data Source

[Presentation] 網膜神経節細胞の蛋白発現異常と緑内障病態2020

Author(s)

Organizer

Data Source

[Presentation] MAPKp38シグナル抑制による視神経軸索保護作用とオートファジー2019

Author(s)

Organizer

Data Source

[Presentation] TNF誘発視神経障害モデルに対するオートファジーとMAPKｐ-ｐ38の関与2019

Author(s)

Organizer

Sase Kana 佐瀬佳奈