Ochi Yosuke 越智洋輔

Researcher Number	30826102
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2019: 大阪薬科大学, 薬学部, 研究員
Review Section/Research Field	Principal Investigator 0801:Pharmaceutical sciences and related fields
Keywords	Principal Investigator 核酸医薬 / ジスルフィド / RNA干渉 / siRNA / プロドラッグ / apoB / 修飾核酸 / 家族性高コレステロール血症 / ApoB / オリゴ核酸合成後修飾 / 炎症性副作用

Development of prodrug-type siRNA reduced inflammatory adverse effectPrincipal Investigator
- Principal Investigator
  
  Ochi Yosuke
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2019 2018

All Journal Article Presentation

[Journal Article] Syntheses of prodrug-type 2'-O-methyldithiomethyl oligonucleotides modified at natural four nucleoside residues and their conversions into natural 2'-hydroxy oligonucleotides under reducing condition2018
- Author(s)
  Hayashi Junsuke、Ochi Yosuke、Morita Yasuyuki、Soubou Katsuma、Ohtomo Yuhei、Nishigaki Misa、Tochiyama Yuko、Nakagawa Osamu、Wada Shun-ichi、Urata Hidehito
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Pages: 5838-5844
- DOI
  10.1016/j.bmc.2018.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21234, KAKENHI-PROJECT-16K08331
[Presentation] 還元環境に応答するプロドラッグ型 RNA の配列拡張を指向した合成研究2019
- Author(s)
  越智洋輔、林淳祐、森田康之、西垣美沙、和田俊一、浦田秀仁
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-19K21234
[Presentation] General synthesis and knockdown activity of prodrug-type 2'-O-methyldithiomethyl oligonucleotide2018
- Author(s)
  越智洋輔、林淳祐、森田康之、西垣美沙、和田俊一、浦田秀仁
- Organizer
  第45回　国際核酸化学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21234
[Presentation] 配列拡張を指向した 2'-O-メチルジチオメチル-オリゴヌクレオチドの合成2018
- Author(s)
  越智洋輔、森田康之、林淳祐、和田俊一、浦田秀仁
- Organizer
  第68回　日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-19K21234

1. 和田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ochi Yosuke 越智洋輔

Research Projects

Research Products

Co-Researchers

Development of prodrug-type siRNA reduced inflammatory adverse effectPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Syntheses of prodrug-type 2'-O-methyldithiomethyl oligonucleotides modified at natural four nucleoside residues and their conversions into natural 2'-hydroxy oligonucleotides under reducing condition2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 還元環境に応答するプロドラッグ型 RNA の配列拡張を指向した合成研究2019

Author(s)

Organizer

Data Source

[Presentation] General synthesis and knockdown activity of prodrug-type 2'-O-methyldithiomethyl oligonucleotide2018

Author(s)

Organizer

Data Source

[Presentation] 配列拡張を指向した 2'-O-メチルジチオメチル-オリゴヌクレオチドの合成2018

Author(s)

Organizer

Data Source

Ochi Yosuke 越智 洋輔

Research Projects

Research Products

Co-Researchers

Development of prodrug-type siRNA reduced inflammatory adverse effectPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Syntheses of prodrug-type 2'-O-methyldithiomethyl oligonucleotides modified at natural four nucleoside residues and their conversions into natural 2'-hydroxy oligonucleotides under reducing condition2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 還元環境に応答するプロドラッグ型 RNA の配列拡張を指向した合成研究2019

Author(s)

Organizer

Data Source

[Presentation] General synthesis and knockdown activity of prodrug-type 2'-O-methyldithiomethyl oligonucleotide2018

Author(s)

Organizer

Data Source

[Presentation] 配列拡張を指向した 2'-O-メチルジチオメチル-オリゴヌクレオチドの合成2018

Author(s)

Organizer

Data Source

Ochi Yosuke 越智洋輔