Okuma Ryotaro 大熊遼太朗

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Ohkuma Ryotaro 大熊遼太朗

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Researcher Number	30833769
Affiliation (Current)	2026: 昭和医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2026: 昭和医科大学, 医学部, 講師 2021 – 2024: 昭和大学, 医学部, 講師 2020: 昭和大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 膵臓がん / 可溶性免疫チェックポイント / バイオマーカー / 免疫チェックポイント阻害薬 / 可溶性PD-L1 / 糖鎖 / 免疫療法 / レクチン / レクチンアレイ / CAR-T / Lectinアレイ / PIGR

糖鎖を介した免疫抑制機構の解明と免疫療法不応性消化器癌の革新的克服戦略Principal Investigator
- Principal Investigator
  
  大熊遼太朗
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Showa Medical University
免疫療法不応の克服に向けた可溶性免疫チェックポイントの解析及び膵臓癌治療への応用Principal Investigator
- Principal Investigator
  
  大熊遼太朗
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Showa University
Analyses of tumor cell-specific glycan structures for the development of next-generation immunotherapy for pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Ohkuma Ryotaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Showa University

All 2023 2022 2020

All Journal Article Presentation

[Journal Article] Soluble PD-L1 changes in advanced non-small cell lung cancer patients treated with PD-1 inhibitors: an individual patient data meta-analysis.2023
- Author(s)
  Shimizu T, Inoue E, Ohkuma R, Kobayashi S, Tsunoda T, Wada S.
- Journal Title
  
  Front Immunol.
  
  Volume: 14 Pages: 1308381-1308381
- DOI
  10.3389/fimmu.2023.1308381
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15085, KAKENHI-PROJECT-21K07866, KAKENHI-PROJECT-23K09700, KAKENHI-PROJECT-20K17210
[Journal Article] Non-classical Monocytes Enhance the Efficacy of Immune Checkpoint Inhibitors on Colon Cancer in a Syngeneic Mouse Model2023
- Author(s)
  GOSHIMA TSUBASA、IEGUCHI KATSUAKI、ONISHI NOBUYUKI、SHIMIZU TAKASHI、…、　HOFFMAN ROBERT M.、TSUNODA TAKUYA、WADA SATOSHI
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 1 Pages: 23-29
- DOI
  10.21873/anticanres.16784
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17210, KAKENHI-PROJECT-23K15085
[Journal Article] High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer2020
- Author(s)
  Ohkuma Ryotaro、Yoshimura Kiyoshi、他
- Journal Title
  
  Oncology Reports
  
  Volume: 44 Issue: 1 Pages: 252-262
- DOI
  10.3892/or.2020.7610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07320, KAKENHI-PROJECT-19K12848, KAKENHI-PROJECT-20K17001, KAKENHI-PROJECT-16H02481
[Journal Article] High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer.2020
- Author(s)
  Ohkuma R, Yada E, Ishikawa S, Komura D, Ishizaki H, Tamada K, Kubota Y, Hamada K, Ishida H, Hirasawa Y, Ariizumi H, Satoh E, Shida M, Watanabe M, Onoue R, Ando K, Tsurutani J, Yoshimura K, Yokobori T, Sasada T, Aoki T, Murakami M, Norose T, Ohike N, Takimoto M, Izumizaki M, Kobayashi S, Tsunoda T, Wada S.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 1 Pages: e0226707-e0226707
- DOI
  10.1371/journal.pone.0226707
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08610, KAKENHI-PROJECT-19K07320, KAKENHI-PROJECT-19K12848, KAKENHI-PROJECT-17H04278, KAKENHI-PROJECT-17H04992, KAKENHI-PROJECT-18K19490, KAKENHI-PROJECT-20K17001
[Presentation] Development of a novel cancer diagnostic method targeting glycosylation on specific molecules.2022
- Author(s)
  渡邊真, 家口勝昭, 大西伸幸, 五嶋翼, 大熊遼太朗, 鈴木梨沙子, 辻まゆみ, 木内祐二, 角田卓也, 内田直樹, 小林真一, 和田聡.
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17001

1. YOSHIMURA Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 清水峻志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 和田聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okuma Ryotaro 大熊 遼太朗

Ohkuma Ryotaro 大熊 遼太朗

Research Projects

Research Products

Co-Researchers

糖鎖を介した免疫抑制機構の解明と免疫療法不応性消化器癌の革新的克服戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

免疫療法不応の克服に向けた可溶性免疫チェックポイントの解析及び膵臓癌治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of tumor cell-specific glycan structures for the development of next-generation immunotherapy for pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Soluble PD-L1 changes in advanced non-small cell lung cancer patients treated with PD-1 inhibitors: an individual patient data meta-analysis.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-classical Monocytes Enhance the Efficacy of Immune Checkpoint Inhibitors on Colon Cancer in a Syngeneic Mouse Model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Development of a novel cancer diagnostic method targeting glycosylation on specific molecules.2022

Author(s)

Organizer

Data Source

Okuma Ryotaro 大熊遼太朗

Ohkuma Ryotaro 大熊遼太朗