Kadonaga Yuichiro 角永悠一郎

Researcher Number	30836903
Other IDs
Affiliation (Current)	2026: 大阪大学, 放射線科学基盤機構, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2026: 大阪大学, 放射線科学基盤機構, 特任准教授(常勤) 2023 – 2025: 大阪大学, 放射線科学基盤機構, 特任助教(常勤) 2022 – 2024: 大阪大学, 大学院医学系研究科, 特任助教(常勤) 2022: 大阪大学, 医学系研究科, 特任助教(常勤) 2019 – 2021: 大阪大学, 放射線科学基盤機構, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 33020:Synthetic organic chemistry-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 52040:Radiological sciences-related / Medium-sized Section 37:Biomolecular chemistry and related fields
Keywords	Principal Investigator がんターゲティング分子 / アスタチン-211 / FAPI / がん間質 / 金-198 / 金ナノ粒子 / がん細胞標的分子 / チロシン / 電解酸化反応 Except Principal Investigator アスタチン211 (At-211) … More / 薬物動態イメージング / Au-198/At-211 / 超解像イメージング / 蛍光飛跡検出器 / アスタチン (At-211) / 標的アイソトープ治療 / 光反応 / 標識法 / アスタチン / レクチン / 合成 / 糖鎖合成 / 複合化 / ワクチン / 免疫 / 糖鎖 Less

がん関連線維芽細胞を標的とした次世代α線核医学治療薬の開発Principal Investigator
- Principal Investigator
  
  角永悠一郎
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  The University of Osaka
From cells to tissues and organs: microscopic and macroscopic dynamic imaging of At-211 for targetted radionuclide therapy
- Principal Investigator
  
  片岡淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Waseda University
Synthesis of 211At-labeled gold nanoparticles for evaluation of anti-tumor activityPrincipal Investigator
- Principal Investigator
  
  角永悠一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Osaka University
紫外光反応によるアスタチン核医学薬剤の新規合成法開発
- Principal Investigator
  
  豊嶋厚史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Osaka University
Development of efficient astatine-211 labeling of cancer-targeting molecules by electrolytic oxidation reactionPrincipal Investigator
- Principal Investigator
  
  Kadonaga Yuichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Osaka University
細菌由来複合糖質ならびに動物由来糖鎖の合成と構造・生物機能研究
- Principal Investigator
  
  深瀬浩一
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Osaka University

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Activation imaging of gold nanoparticles for versatile drug visualization: an in vivo demonstration2025
- Author(s)
  N. Koshikawa, Y. Kikuchi, K. S. Tanaka, K. Tokoi, A. Mitsukai, H. Aoto, Y. Kadonaga, A. Toyoshima, H. Kato, K. Ooe, K. Takamiya, and J. Kataoka
- Journal Title
  
  Applied Physics Letters
  
  Volume: 126 Issue: 10 Pages: 103702-103702
- DOI
  10.1063/5.0251048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24H00804, KAKENHI-PROJECT-23K27456, KAKENHI-PROJECT-23K06049, KAKENHI-PROJECT-24KJ2105
[Journal Article] Comparison Length of Linker in Compound for Nuclear Medicine Targeting Fibroblast Activation Protein as Molecular Target2024
- Author(s)
  Hisada Kentaro、Kaneda-Nakashima Kazuko、Shirakami Yoshifumi、Kadonaga Yuichiro、Saito Atsuko、Watabe Tadashi、Feng Sifan、Ooe Kazuhiro、Yin Xiaojie、Haba Hiromitsu、Murakami Masashi、Toyoshima Atsushi、Cardinale Jens、Giesel Frederik L.、Fukase Koichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 22 Pages: 12296-12296
- DOI
  10.3390/ijms252212296
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04924, KAKENHI-PROJECT-24K02404, KAKENHI-PROJECT-23K06049
[Journal Article] Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models2024
- Author(s)
  Abe Kaori、Watabe Tadashi、Kaneda-Nakashima Kazuko、Shirakami Yoshifumi、Kadonaga Yuichiro、Naka Sadahiro、Ooe Kazuhiro、Toyoshima Atsushi、Giesel Frederik、Usui Takeshi、Masunaga Nanae、Mishima Chieko、Tsukabe Masami、Yoshinami Tetsuhiro、Sota Yoshiaki、Miyake Tomohiro、Tanei Tomonori、Shimoda Masafumi、Shimazu Kenzo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 21 Pages: 11567-11567
- DOI
  10.3390/ijms252111567
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02404, KAKENHI-PROJECT-23K06049
[Journal Article] Wide-band X-ray and gamma-ray imaging for clinical application; visualization of pharmacokinetics in targeted alpha therapy2024
- Author(s)
  N. Koshikawa, M. Masubuchi, J. Kataoka, K. Matsunaga, H. Kato, Y. Kadonaga, A. Toyoshima
- Journal Title
  
  Nuclear Inst. and Methods in Physics Research, A
  
  Volume: 1069 Pages: 169979-169979
- DOI
  10.1016/j.nima.2024.169979
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24H00804, KAKENHI-PROJECT-24KJ2105
[Journal Article] Synthesis of Cage-Shaped Aluminum Aryloxides: Efficient Lewis Acid Catalyst for Stereoselective Glycosylation Driven by Flexible Shift of Four- to Five-Coordination2019
- Author(s)
  Tanaka Daiki、Kadonaga Yuichiro、Manabe Yoshiyuki、Fukase Koichi、Sasaya Shota、Maruyama Hikaru、Nishimura Sota、Yanagihara Mayu、Konishi Akihito、Yasuda Makoto
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 141 Issue: 44 Pages: 17466-17471
- DOI
  10.1021/jacs.9b08875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19079, KAKENHI-PROJECT-19KK0145, KAKENHI-PLANNED-15H05848, KAKENHI-PROJECT-16H01885, KAKENHI-PROJECT-18K14201, KAKENHI-PROJECT-18H01977
[Patent] 電解酸化反応による放射標識アリール化合物の製造方法2023
- Inventor(s)
  深瀬浩一、角永悠一郎、他５名
- Industrial Property Rights Holder
  国立大学法人
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-035169
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-20K15280
[Patent] ハロゲン化フェノール含有化合物の新規アスタチン-211(211At)標識化法の開発2022
- Inventor(s)
  深瀬浩一、角永悠一郎、他
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-035169
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K15280
[Presentation] ピンホール開口コリメータを用いた広帯域・高感度SPECTの提案2024
- Author(s)
  越川七星, 菊池優花, 宇野翔太, 田中香津生，片岡淳, 角永悠一郎, 村上昌史, 豊嶋厚史, 高宮幸一
- Organizer
  第85回応用物理学会秋季年会
- Data Source
  KAKENHI-PROJECT-24H00804
[Presentation] Novel collimator Compton camera for high contrast and wide-band imaging2024
- Author(s)
  N. Koshikawa, Y. Kikuchi, K. S. Tanaka, J. Kataoka, K. Matsunaga, H. Kato, K. Tokoi, A. Mitsukai, Y. Kadonaga, A. Toyoshima, K. Ooe, K. Takamiya
- Organizer
  IEEE Nuclear science symposium and medical imaging conference (2024 IEEE MIC/NSS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00804
[Presentation] Proposal and demonstration of a novel SPECT for high-precision gamma-ray imaging2024
- Author(s)
  N.Koshikawa,Y.Kikuchi, S.Uno, K.S.Tanaka, J.Kataoka, Y.Kadonaga, M.Murakami, A.Toyoshima, K .Takamiya
- Organizer
  6th International Workshop on New Photon-Detectors (PD24)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00804
[Presentation] 電解酸化反応を用いたチロシン上ヨウ素-アスタチン置換反応2022
- Author(s)
  中川創太、角永悠一郎、大江一弘、寺本高啓、床井健運、永田光知郎、吉村崇、羽場宏光、王洋、笠松良崇、豊嶋厚史、深瀬浩一、篠原厚
- Organizer
  日本放射化学会第66回討論会(2022)
- Data Source
  KAKENHI-PROJECT-20K15280
[Presentation] 電解酸化反応を利用したアミノ酸へのアスタチン標識法の開発2022
- Author(s)
  中川創太、角永悠一郎、大江一弘、寺本高啓、床井健運、神田晃充、笠松良崇、永田光知郎、羽場宏光、Wang Yang、吉村崇、豊嶋厚史、篠原厚
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-20K15280
[Presentation] 電解酸化反応を用いた分子標的薬への 211At 標識化法の開発2021
- Author(s)
  中川創太、豊嶋厚史、角永悠一郎、大江一弘、寺本高啓、床井健運、神田晃充、吉村崇、永田光知郎、笠松良崇、羽場宏光、王洋、篠原厚
- Organizer
  日本放射化学会第65回討論会(2021)
- Data Source
  KAKENHI-PROJECT-20K15280
[Presentation] 電解反応を用いた211At標識化法の開発2020
- Author(s)
  中川創太、角永悠一郎、豊嶋厚史、大江一弘、神田晃充、永田光知郎、寺本高啓、床井健運、吉村崇、篠原厚
- Organizer
  日本放射化学会第64回年会(2020)
- Data Source
  KAKENHI-PROJECT-20K15280

1. 深瀬浩一 (80192722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 真鍋良幸 (00632093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 下山敦史 (90625055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 豊嶋厚史 (40414578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 吉村崇 (90323336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 渡部直史 (90648932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 片岡淳 (90334507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 渡部浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 羽場宏光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 兼田加珠子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 仲定宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 大江一弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 白神宜史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 安田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kadonaga Yuichiro 角永 悠一郎

Research Projects

Research Products

Co-Researchers

がん関連線維芽細胞を標的とした次世代α線核医学治療薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

From cells to tissues and organs: microscopic and macroscopic dynamic imaging of At-211 for targetted radionuclide therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthesis of 211At-labeled gold nanoparticles for evaluation of anti-tumor activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

紫外光反応によるアスタチン核医学薬剤の新規合成法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of efficient astatine-211 labeling of cancer-targeting molecules by electrolytic oxidation reactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細菌由来複合糖質ならびに動物由来糖鎖の合成と構造・生物機能研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Activation imaging of gold nanoparticles for versatile drug visualization: an in vivo demonstration2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison Length of Linker in Compound for Nuclear Medicine Targeting Fibroblast Activation Protein as Molecular Target2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wide-band X-ray and gamma-ray imaging for clinical application; visualization of pharmacokinetics in targeted alpha therapy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of Cage-Shaped Aluminum Aryloxides: Efficient Lewis Acid Catalyst for Stereoselective Glycosylation Driven by Flexible Shift of Four- to Five-Coordination2019

Author(s)

Journal Title

DOI

Data Source

[Patent] 電解酸化反応による放射標識アリール化合物の製造方法2023

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] ハロゲン化フェノール含有化合物の新規アスタチン-211(211At)標識化法の開発2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] ピンホール開口コリメータを用いた広帯域・高感度SPECTの提案2024

Kadonaga Yuichiro 角永悠一郎