Iwao Takuro 岩尾卓朗

Researcher Number	30846374
Other IDs
Affiliation (Current)	2026: 福岡大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2026: 福岡大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator 加齢 / DHA / ドコサヘキサエン酸 / ペリサイト / 血液脳関門 / オリゴデンドロサイト / 大脳白質病変 / 再ミエリン化 / 脱髄 / 老化 … More / 脳血管内皮細胞 / Mfsd2a / ドコサヘキサエン酸(DHA) / 細胞老化関連分泌現象(SASP) / 細胞老化 / 脳ペリサイト / MFSD2A / 高齢発症てんかん … More Except Principal Investigator αシヌクレイン / 脳ペリサイト / パーキンソン病 / 頭部外傷 / ペリサイト / 血液脳関門 / 炎症性腸疾患 / 時間治療 / iPS細胞 / 時間薬理学 / 経鼻投与 / ヒトiPS細胞 / 加齢 / alpha-synuclein / PDGFR / PDGFRβ / グルタミン酸 / 神経易興奮性 / ミクログリア / アストロサイト / てんかん Less

脳血管内皮細胞老化制御による大脳白質病変進展抑制の新規治療戦略Principal Investigator
- Principal Investigator
  
  岩尾卓朗
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
パーキンソン病を誘発する腸炎症疾患：腸-脳連関の鍵となる脳ペリサイト病変化の解明
- Principal Investigator
  
  高田芙友子
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes
- Principal Investigator
  
  道具伸也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Fukuoka University
脳ペリサイト加齢性病変化に起因した大脳白質病変の病態進展機構解明とその防御法開発Principal Investigator
- Principal Investigator
  
  岩尾卓朗
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
Role of pericytes in alpha-synuclein accumulation in traumatic brain injury mouse model
- Principal Investigator
  
  Takata Fuyuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fukuoka University
Pathological mechanisms and therapeutic strategies for elderly-onset epilepsy by targeting senescent brain pericytesPrincipal Investigator
- Principal Investigator
  
  Iwao Takuro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Fukuoka University
The role of pericytes in the development of epileptogenesis after traumatic brain injury
- Principal Investigator
  
  TAKATA Fuyuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fukuoka University

All 2025 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] 血液脳関門を介したドコサヘキサエン酸の脳移行2025
- Author(s)
  岩尾卓朗
- Journal Title
  
  脂質栄養学
  
  Volume: 34 Pages: 18-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14401
[Journal Article] α-Synuclein Degradation in Brain Pericytes Is Mediated via Akt, ERK, and p38 MAPK Signaling Pathways2025
- Author(s)
  Yokoya M, Takata F, Iwao T, Matsumoto J, Tanaka Y, Aridome H, Yasunaga M, Mizoguchi J, Sano K, Dohgu S
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 26 Issue: 4 Pages: 1615-1615
- DOI
  10.3390/ijms26041615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18205, KAKENHI-PROJECT-23K14401
[Journal Article] Administration of Noggin Suppresses Fibrinogen Leakage into the Brain in the Acute Phase After Traumatic Brain Injury in Mice2025
- Author(s)
  Yasunaga M, Takata F, Iwao T, Mizoguchi J, Tajima N, Dohgu S.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 26 Issue: 7 Pages: 3002-3002
- DOI
  10.3390/ijms26073002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18205, KAKENHI-PROJECT-23K14401
[Journal Article] Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains.2023
- Author(s)
  Iwao T, Takata F, Matsumoto J, Goto Y, Aridome H, Yasunaga M, Yokoya M, Kataoka Y, Dohgu S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 645 Pages: 154-163
- DOI
  10.1016/j.bbrc.2023.01.037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-20K16065
[Journal Article] Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice2023
- Author(s)
  Iwao T, Takata F, Matsumoto J, Aridome H, Yasunaga M, Yokoya M, Kataoka Y, Dohgu S.
- Journal Title
  
  PLoS One.
  
  Volume: 18 Issue: 2 Pages: e0281946-e0281946
- DOI
  10.1371/journal.pone.0281946
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06703, KAKENHI-PROJECT-20K16065
[Presentation] ドコサヘキサエン酸及びエイコサペンタエン酸は異なるペルオキシソーム増殖因子活性化受容体を介して血液脳関門のバリア機能亢進作用を示す2025
- Author(s)
  岩尾卓朗、丸山愛加、髙田芙友子、田中泰圭、有留尚孝、横谷みき、安永美保、溝口絢子、道具伸也
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] 脳ペリサイトによるα-Synucleinクリアランスとその治療応用2025
- Author(s)
  横谷みき、松本純一、田中泰圭、溝口絢子、高田芙友子、岩尾卓朗、有留尚孝、佐野和憲、道具伸也
- Organizer
  第26回七隈アルツハイマー病/パーキンソン病研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Brain pericytes enhance the expression and plasma membranelocalization of MFSD2A in brain endothelial cells through PDGF-BB/PDGFRβsignaling pathway2025
- Author(s)
  岩尾卓朗、髙田芙友子、有留尚孝、安永美保、横谷みき、溝口絢子、道具伸也
- Organizer
  APPW2025
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] 脳血管内皮細胞の細胞老化におけるペルオキシソーム増殖剤応答性受容体αの関与2025
- Author(s)
  大下莉奈、岩尾卓朗、髙田芙友子、田中泰圭、有留尚孝、横谷みき、安永美保、溝口絢子、道具伸也
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] Exendin-4による血液脳関門構成細胞のαシヌクレインクリアランスの促進2025
- Author(s)
  横谷みき、松本純一、溝口絢子、髙田芙友子、岩尾卓朗、有留尚孝、佐野和憲、道具伸也
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 脳血管内皮細胞におけるToll様受容体を介したαシヌクレイン細胞内取り込み機構2025
- Author(s)
  戸田和澄、高田芙友子、岩尾卓朗、田中泰圭、横谷みき、溝口絢子、有留尚孝、松本純一、佐野和憲、道具伸也
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Exendin-4 enhanced α-Syn clearance in brain pericytes through PI3K/Akt and Erk signaling pathway2025
- Author(s)
  横谷みき, 髙田芙由子, 岩尾卓朗, 松本純一, 安永美保, 溝口絢子, 有留尚孝, 佐野和憲, 道具伸也
- Organizer
  第130回日本解剖学会総会・全国学術集会、第102回日本生理学会大会、第98回日本薬理学会年会　合同大会 APPW2025
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 加齢に伴う血液脳関門バリア機能障害及びグリア細胞の反応性の変化が再ミエリン化に与える影響2025
- Author(s)
  阿波連桃子、岩尾卓朗、内田遥、髙田芙友子、田中泰圭、道具伸也
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] 再ミエリン化過程で生じるBBBバリア機能障害及び神経学的変化に与える加齢の影響2025
- Author(s)
  内田遥、岩尾卓朗、阿波連桃子、髙田芙友子、田中泰圭、道具伸也
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] A vascular endothelial cell-derived factor enhances the ability of iPSC-derived brain pericytes to degrade α-Synuclein2024
- Author(s)
  Miki Yokoya, Yasuyoshi Tanaka, Fuyuko Takata, Junichi Matsumoto, Takuro Iwao, Hisataka Aridome, Junko Mizoguchi, Mayu Shibata, Kazunori Sano, Shinya Dohgu
- Organizer
  International Society for Stem Cell Research (ISSCR) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 血液脳関門構成細胞のα-Synucleinクリアランスに対するexendin-4の効果2024
- Author(s)
  横谷みき、溝口絢子、高田芙友子、松本純一、岩尾卓朗、佐野和憲、道具伸也
- Organizer
  第77回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] マンナン感受性輸送担体を介した単量体αシヌクレインの血液脳関門透過2024
- Author(s)
  道具伸也、横谷みき、高田芙友子、岩尾卓朗、松本純一、安永美保、有留尚孝、溝口絢子、佐野和憲
- Organizer
  NEURO2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 老化促進マウスにおける血液脳関門バリア機能の特性評価2024
- Author(s)
  井上湧太郎、岩尾卓朗、土井優奈、田中泰圭、高田芙友子、道具伸也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] ペリサイトはPDGFB/PDGFRβシグナリングを介して脳血管内皮細胞におけるMFSD2A発現及び細胞膜局在を誘導する2024
- Author(s)
  岩尾卓朗、高田芙友子、田中泰圭、有留尚孝、横谷みき、安永美保、溝口絢子、道具伸也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] 血液脳関門を介したドコサヘキサエン酸の脳移行とその作用2024
- Author(s)
  岩尾卓朗
- Organizer
  第33 回日本脂質栄養学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] 脳ペリサイトのα-Synucleinクリアランスに対するmetforminおよびexendin-4の効果2024
- Author(s)
  横谷みき、根本真奈、得能七海、髙田芙友子、松本純一、岩尾卓朗、田中泰圭、佐野和憲、道具伸也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Cuprizone 誘発性脱髄マウスモデルの再ミエリン化過程における血液脳関門バリア機能の変化2024
- Author(s)
  土井優奈、岩尾卓朗、田中泰圭、高田芙友子、道具伸也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] α-Synucleinクリアランス能を有するヒトiPS細胞由来脳ペリサイトの作製2024
- Author(s)
  横谷みき、田中泰圭、高田芙友子、松本純一、岩尾卓朗、佐野和憲、道具伸也
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 血液脳関門を標的としたパーキンソン病治療法構築を目指して2024
- Author(s)
  道具伸也、横谷みき、田中泰圭、松本純一、岩尾卓朗、佐野和憲、高田芙友子
- Organizer
  第77回日本薬理学会西南部会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Brain pericytes enhance the expression and plasma membrane localization of MFSD2A in brain endothelial cells through PDGF-BB/PDGFRβ signaling pathway2024
- Author(s)
  Takuro Iwao, Fuyuko Takata, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Junko Mizoguchi, Shinya Dohgu
- Organizer
  26th International Symposium on Signal Transduction at the Blood-Brain Barriers
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] ピロカルピン誘発性てんかん発作感受性の加齢に伴う変化とDHA補充の効果2023
- Author(s)
  今村心実、岩尾卓朗、栗山侑子、新垣翔、高田芙友子、道具伸也
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] 脳ペリサイトによるα-シヌクレイン分解機構2023
- Author(s)
  横谷みき、高田芙友子、松本純一、岩尾卓朗、安永美保、佐野和憲、道具伸也
- Organizer
  第13回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice2023
- Author(s)
  Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Shinya Dohgu
- Organizer
  5th Mini-Symposium on The Blood-Brain Barrier from Basic to Clinical Research
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Senescence in brain pericytes attenuates Blood-Brain Barrier function in vitro2023
- Author(s)
  Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Yuki Goto, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Yasufumi Kataoka, Shinya Dohgu
- Organizer
  14th International conference on Cerebral Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14401
[Presentation] 脳ペリサイトのα -Synuclein 消失機構2023
- Author(s)
  横谷みき、髙田芙友子、松本純一、岩尾卓朗、安永美保、佐野和憲、道具伸也
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] パーキンソン病の病態進展における血液脳関門の関与2023
- Author(s)
  道具伸也、高田芙友子、岩尾卓朗、田中泰圭、横谷みき、佐野和憲
- Organizer
  第66回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 老化脳ペリサイトによる血液脳関門バリア機能強化作用の減弱2023
- Author(s)
  岩尾卓朗, 後藤佑季, 高田芙友子, 松本純一, 有留尚孝, 横谷みき, 安永美保, 道具伸也
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] 脳ペリサイトのα-Synucleinクリアランスを促進する治療薬の探索2023
- Author(s)
  横谷みき、髙田芙友子、松本純一、岩尾卓朗、田中泰圭、安永美保、佐野和憲、道具伸也
- Organizer
  第76回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-23K18205
[Presentation] 加齢に伴う血液脳関門のバリア機能脆弱化に対するDHA補充の効果2023
- Author(s)
  栗山侑子, 岩尾卓朗, 今村心実, 新垣翔, 高田芙友子, 道具伸也
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Senescent brain pericytes induced BBB dysfunction by their senescence associated secretory phenotype2022
- Author(s)
  Yuki Goto, Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] 血液脳関門を介した非エステル型ドコサヘキサエン酸の脳移行は加齢に伴い減少する2022
- Author(s)
  岩尾卓朗, 髙田芙友子, 松本純一, 横谷みき, 有留尚孝, 安永美保, 片岡泰文, 道具伸也
- Organizer
  第75回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Aging-induced changes in mRNA expression of dopaminergic neuronrelated genes in C57BL/6 mouse brain2022
- Author(s)
  Eren Tashiro, Fuyuko Takata, Takuro Iwao, Yuko Fukunaga, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06813
[Presentation] Brain pericytes promote brain endothelial DHA uptake through inducing membrane expression of the transporter MFSD2A2022
- Author(s)
  Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Senescent brain pericytes induced BBB dysfunction by their senescence-associated secretory phenotype.2022
- Author(s)
  Yuki Goto, Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Brain pericytes promote brain endothelial DHA uptake through inducing membrane expression of the transporter MFSD2A.2022
- Author(s)
  Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Shinya Dohgu
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Brain Transport of Non-Esterified Docosahexaenoic Acid Across the Blood Brain Barrier is decreased in Middle-Aged and Aged Mice2022
- Author(s)
  岩尾卓朗, 髙田芙友子, 横谷みき, 有留尚孝, 安永美保, 片岡泰文, 道具伸也
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] 加齢によるMfsd2aの機能低下によりドコサヘキサエン酸の脳移行量は減少する2021
- Author(s)
  岩尾卓朗，髙田芙友子，道具伸也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Brain pericytes increase sodium-dependent glutamate uptake in astrocytes.2021
- Author(s)
  髙田芙友子，坂井研太，岩尾卓朗，松本純一，片岡泰文，山内淳史，道具伸也
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] Senescent brain pericytes induced BBB dysfunction by their senescence-associated secretory phenotype.2021
- Author(s)
  Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Yasufumi Kataoka, Shinya Dohgu
- Organizer
  3rd Mini-symposium on the blood-brain barrier from basic to clinical research
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] Enhanced glutamate uptake in the astrocytes cocultured with brain pericytes.2021
- Author(s)
  Fuyuko Takata, Kenta Sakai, Takuro Iwao, Atsushi Yamauchi, Yasufumi Kataoka, Shinya Dohgu
- Organizer
  3rd Mini-symposium on the blood-brain barrier from basic to clinical research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06712
[Presentation] Transport of docosahexaenoic acid across the blood brain barrier is decreased in aged mice.2021
- Author(s)
  岩尾卓朗，髙田芙友子，松本純一，片岡泰文，道具伸也
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] 脳ペリサイトの老化関連随伴分泌現象（SASP）により誘発される血液脳関門機能障害2021
- Author(s)
  岩尾卓朗、高田芙友子、道具伸也
- Organizer
  第74回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-20K16065
[Presentation] 加齢により血液脳関門(BBB)を介したドコサヘキサエン酸の脳移行は減少する2020
- Author(s)
  岩尾卓朗，髙田芙友子，松本純一，片岡泰文，道具伸也
- Organizer
  第73回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-20K16065

1. TAKATA Fuyuko (70412575)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. 道具伸也 (60399186)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
3. 古賀允久 (60570801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 片岡泰文 (70136513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 田中泰圭 (50714466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. 牛島健太郎 (70448843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUMOTO Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 松本太一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Iwao Takuro 岩尾 卓朗

Research Projects

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Co-Researchers

脳血管内皮細胞老化制御による大脳白質病変進展抑制の新規治療戦略Principal Investigator

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パーキンソン病を誘発する腸炎症疾患：腸-脳連関の鍵となる脳ペリサイト病変化の解明

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Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes

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脳ペリサイト加齢性病変化に起因した大脳白質病変の病態進展機構解明とその防御法開発Principal Investigator

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Role of pericytes in alpha-synuclein accumulation in traumatic brain injury mouse model

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Pathological mechanisms and therapeutic strategies for elderly-onset epilepsy by targeting senescent brain pericytesPrincipal Investigator

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The role of pericytes in the development of epileptogenesis after traumatic brain injury

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[Journal Article] 血液脳関門を介したドコサヘキサエン酸の脳移行2025

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[Journal Article] α-Synuclein Degradation in Brain Pericytes Is Mediated via Akt, ERK, and p38 MAPK Signaling Pathways2025

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[Journal Article] Administration of Noggin Suppresses Fibrinogen Leakage into the Brain in the Acute Phase After Traumatic Brain Injury in Mice2025

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[Journal Article] Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains.2023

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[Journal Article] Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice2023

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[Presentation] ドコサヘキサエン酸及びエイコサペンタエン酸は異なるペルオキシソーム増殖因子活性化受容体を介して血液脳関門のバリア機能亢進作用を示す2025

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[Presentation] 脳ペリサイトによるα-Synucleinクリアランスとその治療応用2025

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[Presentation] Brain pericytes enhance the expression and plasma membranelocalization of MFSD2A in brain endothelial cells through PDGF-BB/PDGFRβsignaling pathway2025

Author(s)

Iwao Takuro 岩尾卓朗

[Presentation] 加齢に伴う血液脳関門バリア機能障害及びグリア細胞の反応性の変化が再ミエリン化に与える影響2025

[Presentation] 再ミエリン化過程で生じるBBBバリア機能障害及び神経学的変化に与える加齢の影響2025