Yamamoto Takahiro 山本隆広

… Alternative Names

山本隆広ヤマモトタカヒロ

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Researcher Number	30849089
Other IDs
Affiliation (Current)	2026: 熊本大学, 病院, 助教 2026: 熊本大学, 大学院生命科学研究部(医), 特定研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 熊本大学, 病院, 医員 2023: 熊本大学, 大学院生命科学研究部(医), 病院医員 2019 – 2020: 熊本大学, 病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / 0901:Oncology and related fields
Keywords	Principal Investigator 遺伝子翻訳 / エピトランスクリプトミクス / TRIT1 / RNA修飾 / 膠芽腫 / CDKAL1 / トランスファーRNA修飾 / 神経膠腫 / セレノシステイン / Hippo経路 / tRNA / トランスファーRNA / 悪性脳腫瘍

膠芽腫におけるtRNA修飾機構の解明と新たな治療アプローチの創造Principal Investigator
- Principal Investigator
  
  山本隆広
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kumamoto University
The role of tRNA modifications on the A37 in glioblastoma adenosine (A) at position 37Principal Investigator
- Principal Investigator
  
  Yamamoto Takahiro
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kumamoto University

All 2024 2023

All Journal Article Presentation

[Journal Article] Human DUS1L catalyzes dihydrouridine modification at tRNA positions 16/17, and DUS1L overexpression perturbs translation.2024
- Author(s)
  Matsuura, J., Akichika, S., Wei, F. Y., Suzuki, T., Yamamoto, T., Watanabe, Y., Valasek, L. S., Mukasa, A., Tomizawa, K., & Chujo, T.
- Journal Title
  
  Communications biology
  
  Volume: 7 Issue: 1 Pages: 1238-1238
- DOI
  10.1038/s42003-024-06942-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-21H05258, KAKENHI-PROJECT-24H00065, KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K27713, KAKENHI-PROJECT-23K15650
[Journal Article] CLINICAL CHARACTERIZATION OF H3K27M-MUTANT GLIOMAS2024
- Author(s)
  Takezaki Tatsuya、Kuroda Jun-ichiro、Shinojima Naoki、Kai Keitaro、Yamamoto Takahiro、Fujimoto Kenji、Inoue Hirotaka、Sueyoshi Hiroyuki、Matsuzaki Keisuke、Takeshima Yuki、Matsuura Jin、Mukasa Akitake
- Journal Title
  
  Neuro-Oncology
  
  Volume: 26 Issue: Supplement_8 Pages: viii187-viii188
- DOI
  10.1093/neuonc/noae165.0739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K15650
[Journal Article] Long-term outcomes of multidisciplinary treatment combining surgery and stereotactic radiotherapy with Novalis for craniopharyngioma2024
- Author(s)
  Shinojima Naoki、Yano Shigetoshi、Uchida Daichi、Mizukami Naohisa、Mabe Hiroyo、Kawashima Junji、Igata Motoyuki、Kondo Tatsuya、Uetani Hiroyuki、Yamamoto Takahiro、Uekawa Ken、Hide Takuichiro、Mikami Yoshiki、Hirai Toshinori、Mukasa Akitake
- Journal Title
  
  Journal of Clinical Neuroscience
  
  Volume: 120 Pages: 138-146
- DOI
  10.1016/j.jocn.2024.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08533, KAKENHI-PROJECT-23K27713, KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K15650
[Journal Article] CSIG-17. ADHESION GPCR BAI1/ADGRB1 CAN BLOCK IGF1R-MEDIATED GROWTH SIGNALLING, INCREASE RADIOSENSITIVITY AND AUGMENT SURVIVAL IN MEDULLOBLASTOMA2024
- Author(s)
  Yamamoto Takahiro、De Farias Virginea Araujo、Kuranaga Yuki、Zhu Dan、Parag Rashed R、Osuka Satoru、Van Meir Erwin G
- Journal Title
  
  Neuro-Oncology
  
  Volume: 26 Issue: Supplement_8 Pages: viii67-viii67
- DOI
  10.1093/neuonc/noae165.0266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K15650
[Journal Article] Novel Isoforms of Adhesion G Protein-Coupled Receptor B1 (ADGRB1/BAI1) Generated from an Alternative Promoter in Intron 172024
- Author(s)
  Parag Rashed Rezwan、Yamamoto Takahiro、Saito Kiyotaka、Zhu Dan、Yang Liquan、Van Meir Erwin G.
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 62 Issue: 1 Pages: 900-917
- DOI
  10.1007/s12035-024-04293-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K15650
[Journal Article] EPITRANSCRIPTOMIC TRNA MODIFICATIONS TARGETING ADENOSINE (A) AT POSITION 37 IN GBM2024
- Author(s)
  Yamamoto Takahiro、Matsuura Jin、Fujimura Atsushi、Chujo Takeshi、Wei Fan-Yan、Shinojima Naoki、Kuroda Jun-ichiro、Mukasa Akitake、Tomizawa Kazuhito
- Journal Title
  
  Neuro-Oncology
  
  Volume: 26 Issue: Supplement_8 Pages: viii118-viii118
- DOI
  10.1093/neuonc/noae165.0457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K15650
[Journal Article] CDKAL1 Drives the Maintenance of Cancer Stem‐Like Cells by Assembling the eIF4F Translation Initiation Complex2023
- Author(s)
  Huang Rongsheng、Yamamoto Takahiro、Nakata Eiji、Ozaki Toshifumi、Kurozumi Kazuhiko、Wei Fanyan、Tomizawa Kazuhito、Fujimura Atsushi
- Journal Title
  
  Advanced Science
  
  Volume: 10 Issue: 12 Pages: 2206542-2206542
- DOI
  10.1002/advs.202206542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07618, KAKENHI-PROJECT-20K09325, KAKENHI-PROJECT-23K15650, KAKENHI-PROJECT-19K23920, KAKENHI-PROJECT-23K27710
[Journal Article] Lynch syndrome-associated chordoma with high tumor mutational burden and significant response to immune checkpoint inhibitors2023
- Author(s)
  Shinojima Naoki、Ozono Kazutaka、Yamamoto Haruaki、Abe Sakiko、Sasaki Rumi、Tomita Yusuke、Kai Azusa、Mori Ryosuke、Yamamoto Takahiro、Uekawa Ken、Matsui Hirotaka、Nosaka Kisato、Matsuzaki Hiroaki、Komohara Yoshihiro、Mikami Yoshiki、Mukasa Akitake
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 40 Issue: 3 Pages: 185-190
- DOI
  10.1007/s10014-023-00461-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15650
[Presentation] 悪性神経膠腫におけるA37位tRNA修飾の重要性2024
- Author(s)
  山本隆広
- Organizer
  第83回日本癌学会学術総会 (シンポジウム)
- Data Source
  KAKENHI-PROJECT-19K23920
[Presentation] Epitranscriptomic tRNA modifications targeting adenosine (A) at position 37 in GBM2024
- Author(s)
  Takahiro Yamamoto
- Organizer
  The 29th Annual Meeting of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15650
[Presentation] 悪性神経膠腫におけるA37位tRNA修飾の重要性2024
- Author(s)
  山本隆広
- Organizer
  第83回日本癌学会学術総会 (シンポジウム)
- Data Source
  KAKENHI-PROJECT-23K15650
[Presentation] Epitranscriptomic tRNA modifications targeting adenosine (A) at position 37 in GBM2024
- Author(s)
  Takahiro Yamamoto
- Organizer
  The 29th Annual Meeting of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23920

1. KUROZUMI Kazuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 魏范研

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 富澤一仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 藤村篤史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 近藤龍也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamoto Takahiro 山本 隆広

山本 隆広 ヤマモト タカヒロ

Research Projects

Research Products

Co-Researchers

膠芽腫におけるtRNA修飾機構の解明と新たな治療アプローチの創造Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of tRNA modifications on the A37 in glioblastoma adenosine (A) at position 37Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Human DUS1L catalyzes dihydrouridine modification at tRNA positions 16/17, and DUS1L overexpression perturbs translation.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CLINICAL CHARACTERIZATION OF H3K27M-MUTANT GLIOMAS2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term outcomes of multidisciplinary treatment combining surgery and stereotactic radiotherapy with Novalis for craniopharyngioma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CSIG-17. ADHESION GPCR BAI1/ADGRB1 CAN BLOCK IGF1R-MEDIATED GROWTH SIGNALLING, INCREASE RADIOSENSITIVITY AND AUGMENT SURVIVAL IN MEDULLOBLASTOMA2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Isoforms of Adhesion G Protein-Coupled Receptor B1 (ADGRB1/BAI1) Generated from an Alternative Promoter in Intron 172024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EPITRANSCRIPTOMIC TRNA MODIFICATIONS TARGETING ADENOSINE (A) AT POSITION 37 IN GBM2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CDKAL1 Drives the Maintenance of Cancer Stem‐Like Cells by Assembling the eIF4F Translation Initiation Complex2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lynch syndrome-associated chordoma with high tumor mutational burden and significant response to immune checkpoint inhibitors2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] 悪性神経膠腫におけるA37位tRNA修飾の重要性2024

Author(s)

Organizer

Data Source

[Presentation] Epitranscriptomic tRNA modifications targeting adenosine (A) at position 37 in GBM2024

Author(s)

Organizer

Data Source

[Presentation] 悪性神経膠腫におけるA37位tRNA修飾の重要性2024

Author(s)

Organizer

Data Source

[Presentation] Epitranscriptomic tRNA modifications targeting adenosine (A) at position 37 in GBM2024

Author(s)

Organizer

Data Source

Yamamoto Takahiro 山本隆広

山本隆広ヤマモトタカヒロ