Tachinami Hidetake 立浪秀剛

Researcher Number	30850268
Affiliation (Current)	2025: 富山大学, 医学部, 協力研究員
Affiliation (based on the past Project Information) *help	2024: 富山大学, 医学部, 協力研究員 2023: 富山大学, 学術研究部医学系, 助教 2022: 富山大学, 附属病院, 助教 2019 – 2022: 富山大学, 附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / 0907:Oral science and related fields Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 腫瘍免疫 / 口腔癌 / PD-1免疫チェックポイント阻害剤 / immune therapy / oral cancer / 骨髄由来抑制性細胞 / PD-1 / TAM / TAN / MDSC / 口腔扁平上皮癌 / 骨髄抑制性細胞 / 免疫チェックポイント阻害剤 … More Except Principal Investigator … More 免疫抑制性細胞 / 好中球 / 免疫抑制 / 免疫チェックポイント / 口腔がん / 腫瘍関連好中球 / 好中球・リンパ球数比 / 腫瘍関連免疫抑制性細胞 / 免疫チェックポイント阻害剤 / 免疫療法 / 口腔癌 Less

Development of Immunological therapeutic strategies targeting polymorphonuclear myeloid derived suppressor cells for Oral CancerPrincipal Investigator
- Principal Investigator
  
  立浪秀剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Toyama
腫瘍関連免疫抑制性細胞を標的とした口腔癌に対する新たな免疫療法の開発研究
- Principal Investigator
  
  冨原圭
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Niigata University
Development of immunological treatment strategies targeting cancer-infiltrating myeloid lineage cells for oral cancerPrincipal Investigator
- Principal Investigator
  
  TACHINAMI Hidetake
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  University of Toyama
Development of combined immunotherapy targeting tumor-infiltrating myeloid cells for oral cancerPrincipal Investigator
- Principal Investigator
  
  Tachinami Hidetake
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  University of Toyama

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Neutrophil-to-lymphocyte ratio as an early marker of outcomes in patients with recurrent oral squamous cell carcinoma treated with nivolumab2023
- Author(s)
  Tachinami H, Tomihara K,Yamada S, Ikeda A, Imaue S, Hirai H, Nakai H, Sonoda T, Kurohara K, Yoshioka Y, Hasegawa T, Naruse T, Niiyama T, Shimane T, Ueda M, Yanamoto S, Akashi M, Umeda M, Kurita H, Miyazaki A, Arai N, Hayashi R, Noguchi M
- Journal Title
  
  British Journal of Oral and Maxillofacial Surgery
  
  Volume: 61 Issue: 4 Pages: 320-326
- DOI
  10.1016/j.bjoms.2023.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10214, KAKENHI-PROJECT-21K17111, KAKENHI-PROJECT-20K10157, KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-23K27794
[Journal Article] Treatment of severe micrognathia in an adult with distraction osteogenesis: A case report2023
- Author(s)
  Sekido Katsuhisa、Fujiwara Kumiko、Tachinami Hidetake、Imaue Shuichi、Hanashiro Keishi、Noguchi Makoto
- Journal Title
  
  Clinical Case Reports
  
  Volume: 11 Issue: 6
- DOI
  10.1002/ccr3.7327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17111
[Journal Article] Successful treatment with nivolumab in a patient with unresectable oral squamous cell carcinoma following ineffective chemoradiotherapy2023
- Author(s)
  Sekido Katsuhisa、Imaue Shuichi、Tachinami Hidetake、Tomihara Kei、Naruto Norihito、Yamagishi Kentaro、Ikeda Atsushi、Fujiwara Kumiko、Noguchi Makoto
- Journal Title
  
  Clinical Case Reports
  
  Volume: 11 Issue: 12
- DOI
  10.1002/ccr3.8219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-21K17111
[Journal Article] Complete Response to Cetuximab Plus Paclitaxel Therapy in Nivolumab-Refractory Patients in Distant Metastasis of Squamous Cell Carcinoma of the Tongue: A Report of Two Cases2023
- Author(s)
  Tachinami Hidetake、Tomihara Kei、Takatsuka Danki、Ikeda Atsushi、Yamada Shin-ichi、Noguchi Makoto
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.49198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-21K17111
[Journal Article] Complete response to cetuximab plus paclitaxel therapy in nivolumab-refractory patients in distant metastasis of squamous cell carcinoma of the tongue: a report of two cases2022
- Author(s)
  Tachinami Hidetake、Tomihara Kei、Takatsuka Danki、Ikeda Atsushi、Yamada Shinichi、Noguchi Makoto
- Journal Title
  
  Clinical Case Reports
  
  Volume: in press
- DOI
  10.22541/au.165881754.43971495/v1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-21K17111
[Journal Article] Perioperative bridging anticoagulation in patients with oral cancer surgery: a multicenter retrospective study2022
- Author(s)
  Kajihara Ryo、Yamada Shin-ichi、Noguchi Makoto
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 34 Issue: 6 Pages: 734-739
- DOI
  10.1016/j.ajoms.2022.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-21K17111
[Journal Article] Protumor role of estrogen receptor expression in oral squamous cell carcinoma cells2021
- Author(s)
  Akyu Takei R, Tomihara K, Yamazaki M, Moniruzzaman R, Heshiki W, Sekido K, Tachinami H, Sakurai K, Yonesi A, Imaue S, Fujiwara K, Noguchi M.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol.
  
  Volume: 132 Issue: 5 Pages: 549-565
- DOI
  10.1016/j.oooo.2021.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-21K09856, KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-21K17111
[Journal Article] Neutrophil-to-Lymphocyte Ratio(NLR)as a Predictive Indicator of the Response to Nivolumab in Patients with Oral Squamous Cell Carcinoma2021
- Author(s)
  Tachinami H, Tomihara K, Ikeda A, Sekido K, Sakurai K, Imaue S, Fujiwara K, Hayashi R, Noguchi M.
- Journal Title
  
  Gan To Kagaku Ryoho.
  
  Volume: 48 Pages: 1485-1490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17111
[Journal Article] Durable complete response to immunotherapy with anti-PD-1 antibody nivolumab in a patient with oral squamous cell carcinoma presenting with lung metastasis: A case report.2021
- Author(s)
  Sekido K, Imaue, Tomihara K, Tachinami H, Yamagishi K, Okazawa S, Ikeda A, Fujiwara K, Noguchi M.
- Journal Title
  
  Clin Case Rep.
  
  Volume: 9 Issue: 9
- DOI
  10.1002/ccr3.4545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10262, KAKENHI-PROJECT-19K19049, KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-21K10065, KAKENHI-PROJECT-21K17111
[Journal Article] Neutrophil-to-Lymphocyte Ratio(NLR)as a Predictive Indicator of the Response to Nivolumab in Patients with Oral Squamous Cell Carcinoma2021
- Author(s)
  Tachinami H, Tomihara K, Ikeda A, Sekido K, Sakurai K, Imaue S, Fujiwara K, Hayashi R, Noguchi M.
- Journal Title
  
  Gan To Kagaku Ryoho.
  
  Volume: 48 Pages: 1485-1490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K24088
[Journal Article] Enhanced expression of PD-L1 in oral squamous cell carcinoma-derived CD11b + Gr-1 + cells and its contribution to immunosuppressive activity2020
- Author(s)
  Fuse Hiroki、Tomihara Kei、Heshiki Wataru、Yamazaki Manabu、Akyu-Takei Rie、Tachinami Hidetake、Furukawa Ken-ichiro、Sakurai Kotaro、Rouwan Moniruzzaman、Noguchi Makoto
- Journal Title
  
  Oral Oncology
  
  Volume: 59 Pages: 20-29
- DOI
  10.1016/j.oraloncology.2016.05.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088
[Journal Article] CD36 expression on oral squamous cell carcinoma cells correlates with enhanced proliferation and migratory activity.2020
- Author(s)
  Sakurai K, Tomihara K, Yamazaki M, Heshiki W, Moniruzzaman R, Sekido K, Tachinami H, Ikeda A, Imaue S, Fujiwara K, Noguchi M.
- Journal Title
  
  Oral Dis.
  
  Volume: 0000 Issue: 4 Pages: 0000-0000
- DOI
  10.1111/odi.13210
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-18K09533
[Journal Article] Orthotopic tongue squamous cell carcinoma (SCC) model exhibiting a different tumor-infiltrating T-cell status with margin-restricted CD8+ T cells and regulatory T cell-dominance, compared to skin SCC.2020
- Author(s)
  Kashima Y, Nishii N, Tachinami H, Furusawa E, Nagai S, Harada H, Azuma M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 20 Issue: 1 Pages: 218-224
- DOI
  10.1016/j.bbrc.2020.03.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-19K24138, KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376
[Journal Article] Endogenous IL-33 exerts CD8+ T cell antitumor responses overcoming pro-tumor effects by regulatory T cells in a colon carcinoma model.2019
- Author(s)
  Xia Y, Ohno T, Nishii N, Bhingare A, Tachinami H, Kashima Y, Nagai S, Saito H, Nakae S, Azuma M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 2019 Issue: 2 Pages: 331-336
- DOI
  10.1016/j.bbrc.2019.08.058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088, KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-17K11663
[Journal Article] Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR7 agonist and PD-L1 blockade2019
- Author(s)
  Tachinami Hidetake、Nishii Naoto、Xia Yulong、Kashima Yoshihisa、Ohno Tatsukuni、Nagai Shigenori、Li Lixin、Lau Walter、Tomihara Kei、Noguchi Makoto、Azuma Miyuki
- Journal Title
  
  Oral Oncology
  
  Volume: 91 Pages: 21-28
- DOI
  10.1016/j.oraloncology.2019.02.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04066, KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-19K24088
[Journal Article] Alterations in composition of immune cells and impairment of anti-tumor immune response in aged oral cancer-bearing mice.2019
- Author(s)
  Sekido K, Tomihara K, Tachinami H, Heshiki W, Sakurai K, Moniruzzaman R, Imaue S, Fujiwara K, Noguchi M.
- Journal Title
  
  Oral Oncol.
  
  Volume: 99 Pages: 104462-104462
- DOI
  10.1016/j.oraloncology.2019.104462
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24088
[Journal Article] Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy.2018
- Author(s)
  Nishii N, Tachinami H, Kondo Y, Xia Y, Kashima Y, Ohno T, Nagai S, Li L, Lau W, Harada H, Azuma M.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 17 Pages: 13301-13312
- DOI
  10.18632/oncotarget.24327
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04376, KAKENHI-PROJECT-19K24088
[Presentation] Rapamycin induces phenotypic alterations of oral cancer cells that facilitate antitumor T cell response2023
- Author(s)
  Yonesi Amrimoezz, 冨原圭, 高塚団貴, 立浪秀剛, 山崎学, 高市真由, Younesi Amirreza, 山田慎一, 田沼順一, 野口誠
- Organizer
  第77回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 癌化学療法の口腔粘膜炎治療の基礎的研究2023
- Author(s)
  山口百々穂, 立浪秀剛, 高塚団貴, 高市真由, 冨原圭, 山田慎一, 野口誠
- Organizer
  第68回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Applications of the hyperdried human amniotic membrane in oral surgery2023
- Author(s)
  Tachinami H, Arai N, Tsuno H, Fujiwara K, Imaue S, Kurohara K, Yamada S, Tomihara K, Noguchi M
- Organizer
  2nd Japanese-German CMF Symposium
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] ニボルマブによる完全奏功後，2年未満で投与終了となり再発した舌癌の1例2023
- Author(s)
  石坂理紗, 立浪秀剛, 今上修一, 石戸克尚, 池田篤司, 高塚団貴, 櫻井航太郎, 山田慎一, 野口誠
- Organizer
  第49回日本口腔外科学会北日本支部学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 肩甲骨皮弁採取における肩甲下動脈を標的とした術前3D CT angiographyの有用性2023
- Author(s)
  今上修一, 石戸克尚, 高市真由, 藤原久美子, 冨原圭, 立浪秀剛, 櫻井航太郎, 池田篤司, 山田慎一, 野口誠
- Organizer
  第66回NPO法人日本口腔科学会中部地方会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 超選択的動注化学放射線療法後にニボルマブが奏功した局所進行下顎歯肉癌の1例2023
- Author(s)
  立浪秀剛, 今上修一, 石戸克尚, 山田慎一, 野口誠
- Organizer
  第77回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔癌におけるPAK4阻害による免疫学的修飾作用2023
- Author(s)
  高塚団貴*, 立浪秀剛, 櫻井航太郎, 高市真由*, 冨原圭, 山田慎一, 野口誠
- Organizer
  第68回公益社団法人日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Pembrolizumabを投与した再発・転移口腔癌の治療成績2023
- Author(s)
  櫻井航太郎, 山田慎一, 今上修一, 池田篤司, 立浪秀剛, 野口誠
- Organizer
  第48回公益社団法人日本口腔外科学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Vascularized scapula bone graft using angular branch in maxillofacial reconstruction2023
- Author(s)
  Imaue S, Tomihara K, Yamada S, Ikeda A, Tachinami H, Sakurai K, Takaichi M*, Ishizaka R*, Fujiwara K, Noguchi M
- Organizer
  13th Joint Scientific Meeting of NAOMS and JSOMS
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] ニボルマブ投与後に救済化学療法が奏功した舌癌の2例2022
- Author(s)
  高塚団貴，立浪秀剛，冨原　圭，池田篤司，今上修一，藤原久美子，山田慎一，野口　誠
- Organizer
  第67回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口底に生じたリンパ節転移を伴った低悪性度粘表皮癌の1例2022
- Author(s)
  櫻井航太郎, 今上修一, 池田篤司, 立浪秀剛, 野口　誠
- Organizer
  第40回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Treatment Outcome of Patients with StageIVB Oral Squamous cell carcinoma(OSCC).2022
- Author(s)
  Imaue S, Ikeda A, Tachinami H, Sakurai K, Takaichi M, Ishizaka R, Fujiwara K, Tomihara K, Noguchi M
- Organizer
  12th Annual Conference of Nepalese Association of Oral and Maxillofacial Surgeons and Joint Meeting with Japanese Society of Oral and Maxillofacial Surgeons
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Rapamycin induces phenotypic alterations of oral cancer cells that facilitate antitumor T cell response2022
- Author(s)
  Yonesi Amirmoezz，冨原　圭，高塚団貴，立浪秀剛，櫻井航太朗, 野口　誠
- Organizer
  第76回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔扁平上皮癌・手術不能局所進展例の治療戦略2022
- Author(s)
  今上修一, 池田篤司, 石戸克尚, 立浪秀剛, 桜井航太郎, 冨原　圭, 野口　誠
- Organizer
  第40回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔がんにおける脂質代謝を介した免疫抑制機能の解析2022
- Author(s)
  高市真由, 櫻井航太朗, 立浪秀剛, 高塚団貴, 冨原　圭, 山田慎一, 野口　誠
- Organizer
  第67回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Neutrophil-to-lymphocyte ratio as an early marker of outcomes in patients with recurrent oral squamous cell carcinoma treated with nivolumab: a pilot study.2022
- Author(s)
  Tachinami H, Tomihara K, Yamada S, Miyazaki A, Arai N, Hayashi R, Noguchi M
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔癌切除後再建に用いた前腕皮弁に発生した扁平上皮癌の一例．2021
- Author(s)
  津波古康太，池田篤司，今上修一，立浪秀剛，櫻井航太郎，高市真由，野口誠．
- Organizer
  第46回日本口腔外科学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] Rapamycin induces phenotypic alterations of oral cancer cells that facilitate antitumor T cell response.2021
- Author(s)
  Yonesi Amirmoezz，冨原　圭，高塚団貴，立浪秀剛，高市真由，櫻井航太朗，Younesi Jadidi Amirreza, 野口　誠.
- Organizer
  57回日本口腔組織培養学会学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔扁平上皮癌に対するニボルマブの効果と好中球/リンパ球比に関する研究．2021
- Author(s)
  立浪　秀剛，冨原　圭，池田篤司，今上修一，岡本準也，中井裕美，黒原一人，宮﨑晃亘，新井直也，野口　誠．
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 口腔癌に対するPAK4阻害による免疫学的修飾作用の解析．2021
- Author(s)
  高塚団貴，冨原　圭，立浪秀剛，櫻井航太朗，高市真由，Yonesi Amirmoezz，野口　誠.
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Rapamycin induces phenotypic alterations of oral cancer cells that facilitate antitumor T cell response．2021
- Author(s)
  Yonesi Amirmoezz，冨原　圭，高塚団貴，立浪秀剛，櫻井航太朗, 野口　誠.
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] Rapamycin induces phenotypic alterations of oral cancer cells that facilitate antitumor T cell response．2021
- Author(s)
  Yonesi Amirmoezz，冨原　圭，高塚団貴，立浪秀剛，櫻井航太朗, 野口　誠.
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 口腔扁平上皮癌に対するニボルマブの効果と好中球/リンパ球比に関する研究．2021
- Author(s)
  立浪　秀剛，冨原　圭，池田篤司，今上修一，岡本準也，中井裕美，黒原一人，宮﨑晃亘，新井直也，野口　誠．
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔癌に対するPAK4阻害による免疫学的修飾作用の解析．2021
- Author(s)
  高塚団貴，冨原　圭，立浪秀剛，櫻井航太朗，高市真由，Yonesi Amirmoezz，野口　誠.
- Organizer
  第66回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 口腔癌切除後再建に用いた前腕皮弁に発生した扁平上皮癌の一例．2021
- Author(s)
  津波古康太，池田篤司，今上修一，立浪秀剛，櫻井航太郎，高市真由，野口誠．
- Organizer
  第46回日本口腔外科学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 口腔癌に対するPAK4阻害による免疫学的修飾作用の解析．2021
- Author(s)
  高塚団貴，冨原　圭，立浪秀剛，櫻井航太朗，高市真由，Yonesi Amirmoezz，野口　誠.
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 口腔癌に対するPAK4阻害による免疫学的修飾作用の解析．2021
- Author(s)
  高塚団貴，冨原　圭，立浪秀剛，櫻井航太朗，高市真由，Yonesi Amirmoezz，野口　誠.
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17111
[Presentation] 広範囲顎骨支持型装置を適用した症例の治療成績2020
- Author(s)
  高塚団貴，立浪秀剛，津野宏彰，布施　浩樹，野口　誠
- Organizer
  第39回日本口腔インプラント学会関東甲信越支部学術大会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 腫瘍に集積するミエロイド系細胞の違いはPD-L1阻害剤との併用免疫療法効果に影響を与える2019
- Author(s)
  立浪秀剛，西井　直人，加島　義久，冨原　圭，野口　誠，東　みゆき
- Organizer
  第73回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 老齢口腔癌マウスを用いた免疫細胞および抗腫瘍免疫応答に関する研究2019
- Author(s)
  石戸克尚，立浪秀剛，櫻井航太郎，平識　亘，冨原　圭，野口　誠
- Organizer
  第64回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] CT所見による下顎第三大臼歯抜歯後のオトガイ神経障害におけるハイリスク症例の検討2019
- Author(s)
  高塚団貴，立浪秀剛，藤原久美子，仲盛健治，冨原圭，野口誠
- Organizer
  第64回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR agonist and PD-L1 blockade2019
- Author(s)
  Azuma M, Tachinami H, Nishii N, Xia Y, Kashima Y, Nagai S, Li L, Tomihara K, Noguchi M
- Organizer
  17th Congress of the International Union of Immunological Societies (IUIS)
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 骨吸収抑制薬関連顎骨壊死（ARONJ）に関する臨床的検討2019
- Author(s)
  平識　亘，石戸克尚，立浪秀剛，朝倉みな実，冨原　圭，野口　誠
- Organizer
  第62回日本口腔科学会中部地方部会学術集会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 口腔癌におけるnivolumab投与による好中球数/リンパ球数比の変化2019
- Author(s)
  立浪秀剛，冨原　圭，石戸克尚，池田篤司，藤原久美子，野口　誠
- Organizer
  第64回日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] 広範囲顎骨支持型装置を適用した症例の治療成績2019
- Author(s)
  高塚団貴，立浪秀剛，今上修一，津野宏彰，石戸克尚，佐渡忠司，冨原圭，野口　誠
- Organizer
  第23回公益社団法人日本顎顔面インプラント学会総会・学術大会，18th Annual meeting of Pan Pacific Implant Society (PPIS)
- Data Source
  KAKENHI-PROJECT-19K24088
[Presentation] Neutrophil-to-lymphocyte ratio as a predictable biomarker for response to nivolumab in oral squamous cell carcinoma2019
- Author(s)
  Tachinami H, Tomihara K, Noguchi M
- Organizer
  The 78th J Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19K24088

1. 冨原圭 (70404738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 山崎学 (10547516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 野口誠 (50208328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. FUJIWARA Kumiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 永井重徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 大野建州

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 東みゆき

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tachinami Hidetake 立浪 秀剛

Research Projects

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Co-Researchers

Development of Immunological therapeutic strategies targeting polymorphonuclear myeloid derived suppressor cells for Oral CancerPrincipal Investigator

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腫瘍関連免疫抑制性細胞を標的とした口腔癌に対する新たな免疫療法の開発研究

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Development of immunological treatment strategies targeting cancer-infiltrating myeloid lineage cells for oral cancerPrincipal Investigator

Principal Investigator

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Development of combined immunotherapy targeting tumor-infiltrating myeloid cells for oral cancerPrincipal Investigator

Principal Investigator

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[Journal Article] Neutrophil-to-lymphocyte ratio as an early marker of outcomes in patients with recurrent oral squamous cell carcinoma treated with nivolumab2023

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[Journal Article] Treatment of severe micrognathia in an adult with distraction osteogenesis: A case report2023

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[Journal Article] Successful treatment with nivolumab in a patient with unresectable oral squamous cell carcinoma following ineffective chemoradiotherapy2023

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[Journal Article] Complete Response to Cetuximab Plus Paclitaxel Therapy in Nivolumab-Refractory Patients in Distant Metastasis of Squamous Cell Carcinoma of the Tongue: A Report of Two Cases2023

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[Journal Article] Complete response to cetuximab plus paclitaxel therapy in nivolumab-refractory patients in distant metastasis of squamous cell carcinoma of the tongue: a report of two cases2022

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[Journal Article] Perioperative bridging anticoagulation in patients with oral cancer surgery: a multicenter retrospective study2022

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[Journal Article] Protumor role of estrogen receptor expression in oral squamous cell carcinoma cells2021

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[Journal Article] Neutrophil-to-Lymphocyte Ratio(NLR)as a Predictive Indicator of the Response to Nivolumab in Patients with Oral Squamous Cell Carcinoma2021

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[Journal Article] Durable complete response to immunotherapy with anti-PD-1 antibody nivolumab in a patient with oral squamous cell carcinoma presenting with lung metastasis: A case report.2021

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[Journal Article] Neutrophil-to-Lymphocyte Ratio(NLR)as a Predictive Indicator of the Response to Nivolumab in Patients with Oral Squamous Cell Carcinoma2021

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[Journal Article] Enhanced expression of PD-L1 in oral squamous cell carcinoma-derived CD11b + Gr-1 + cells and its contribution to immunosuppressive activity2020

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Tachinami Hidetake 立浪秀剛