Kato Masato 加藤昌人

Researcher Number	30867768
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 上席研究員
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related
Keywords	Principal Investigator 相分離液滴 / ラマンスペクトル / 放射光CD / low-complexity sequence / ALS変異体 / 相分離 / low-complexityドメイン / クロスβ構造 / 中性子散乱 / ラマン顕微鏡 … More / CD / 液－液相分離 / 高速原子間力顕微鏡 / Raman spectrum / circular dichroism / neutron scattering / cross-beta polymer / phase separation / 神経変性疾患変異 / cross-b fiber / low-complexity domain / 液‐液相分離 Less

Spectroscopic analysis of phase-separated liquid droplets made from low-complexity sequencesPrincipal Investigator
- Principal Investigator
  
  加藤昌人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  National Institutes for Quantum Science and Technology

All 2023 2022

All Journal Article Presentation

[Journal Article] Molecular Mechanisms Defining the Structural Basis for Self-Association of the FUS Low-Complexity Domain2023
- Author(s)
  Kato Masato
- Journal Title
  
  Riki Kurokawa, ed., “Phase Separation in Living Cells”, Springer, Singapore
  
  Volume: - Pages: 93-109
- DOI
  10.1007/978-981-99-4886-4_6
- ISBN
  9789819948857, 9789819948864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch2023
- Author(s)
  Gu Jinge、Zhou Xiaoming、Sutherland Lillian、Kato Masato、Jaczynska Klaudia、Rizo Josep、McKnight Steven L.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 41
- DOI
  10.1073/pnas.2311416120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] 神経変性疾患変異による線維凝集体形成の構造学的機構‐low-complexityドメインの機能に与える影響2023
- Author(s)
  加藤昌人
- Journal Title
  
  実験医学　増刊号　小野賢二郎／編　いま新薬で加速する神経変性疾患研究異常タンパク質の構造、凝集のしくみから根本治療の真の標的に迫る
  
  Volume: 41
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] How do disordered head domains assist in the assembly of intermediate filaments?2023
- Author(s)
  Zhou Xiaoming、Kato Masato、McKnight Steven L.
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 85 Pages: 102262-102262
- DOI
  10.1016/j.ceb.2023.102262
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] リコンビナントlow-complexityドメインの精製法2022
- Author(s)
  加藤昌人
- Journal Title
  
  実験医学　別冊　フロントランナー直伝　相分離　解析プロトコール
  
  Volume: 7月号 Pages: 76-89
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] ハイドロゲル結合実験によるlow-complexity配列の線維形成能の評価2022
- Author(s)
  加藤昌人
- Journal Title
  
  実験医学　別冊　フロントランナー直伝　相分離　解析プロトコール
  
  Volume: 7月号 Pages: 90-105
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] Mutations linked to neurological disease enhance self-association of low-complexity protein sequences2022
- Author(s)
  Zhou Xiaoming、Sumrow Lily、Tashiro Kyuto、Sutherland Lillian、Liu Daifei、Qin Tian、Kato Masato、Liszczak Glen、McKnight Steven L.
- Journal Title
  
  Science
  
  Volume: 377 Issue: 6601
- DOI
  10.1126/science.abn5582
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] Low-complexity配列に特異的に作用する低分子化合物 - biotinylated isoxazoleと1,6-hexanediol2022
- Author(s)
  加藤昌人
- Journal Title
  
  実験医学　別冊　フロントランナー直伝　相分離　解析プロトコール
  
  Volume: 7月号 Pages: 106-114
- Data Source
  KAKENHI-PROJECT-23K23857
[Journal Article] Low-complexity配列による相分離・相転移機構2022
- Author(s)
  加藤昌人
- Journal Title
  
  実験医学　別冊　フロントランナー直伝　相分離　解析プロトコール
  
  Volume: 7月号 Pages: 22-31
- Data Source
  KAKENHI-PROJECT-23K23857
[Presentation] Secondary Structural Changes in FUS-LC causing Liquid-Liquid Phase Separation2023
- Author(s)
  Fujii K, Izumi Y, Maita N, Matsuo K, Kato M
- Organizer
  CD2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23857
[Presentation] 神経変性疾患変異による線維凝集体形成の構造学的機構2023
- Author(s)
  加藤昌人
- Organizer
  33rd Forum in DOJIN
- Invited
- Data Source
  KAKENHI-PROJECT-23K23857
[Presentation] Observation of Liquid-Liquid Phase Separation of FUS-LC using Synchrotron CD Spectroscopy2022
- Author(s)
  Fujii Kentaro, Maita Nobuo, Koichi Matsuo, Kato Masato
- Organizer
  18th International Conference on Chiroptical Spectroscopy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23857
[Presentation] TDP43-LCドメインの病原性変異と線維形成能の網羅的解析2022
- Author(s)
  真板宣夫，梶野裕子，加藤昌人
- Organizer
  日本生物物理第60回年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K23857

1. 藤井健太郎 (00360404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 中川洋 (20379598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中林孝和 (30311195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松尾龍人 (60623907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Kato Masato 加藤 昌人

Research Projects

Research Products

Co-Researchers

Spectroscopic analysis of phase-separated liquid droplets made from low-complexity sequencesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Molecular Mechanisms Defining the Structural Basis for Self-Association of the FUS Low-Complexity Domain2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 神経変性疾患変異による線維凝集体形成の構造学的機構‐low-complexityドメインの機能に与える影響2023

Author(s)

Journal Title

Data Source

[Journal Article] How do disordered head domains assist in the assembly of intermediate filaments?2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] リコンビナントlow-complexityドメインの精製法2022

Author(s)

Journal Title

Data Source

[Journal Article] ハイドロゲル結合実験によるlow-complexity配列の線維形成能の評価2022

Author(s)

Journal Title

Data Source

[Journal Article] Mutations linked to neurological disease enhance self-association of low-complexity protein sequences2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low-complexity配列に特異的に作用する低分子化合物 - biotinylated isoxazoleと1,6-hexanediol2022

Author(s)

Journal Title

Data Source

[Journal Article] Low-complexity配列による相分離・相転移機構2022

Author(s)

Journal Title

Data Source

[Presentation] Secondary Structural Changes in FUS-LC causing Liquid-Liquid Phase Separation2023

Author(s)

Organizer

Data Source

[Presentation] 神経変性疾患変異による線維凝集体形成の構造学的機構2023

Author(s)

Organizer

Data Source

[Presentation] Observation of Liquid-Liquid Phase Separation of FUS-LC using Synchrotron CD Spectroscopy2022

Author(s)

Organizer

Data Source

[Presentation] TDP43-LCドメインの病原性変異と線維形成能の網羅的解析2022

Author(s)

Organizer

Data Source

Kato Masato 加藤昌人