SHIIBA ISSHIN 椎葉一心

Researcher Number	30884481
Other IDs
Affiliation (Current)	2025: 学習院大学, 理学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 学習院大学, 理学部, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator ミトコンドリア / ROS / オルガネラコンタクト / MITOL/MARCHF5 / アグリソーム / ユビキチン / ユビキチンリガーゼ / NanoBiT / オルガネラ接触定量ツール / 酸化ストレス … More / オルガネラバイオロジー / 硫黄生物学 / オルガネラ膜接触 / MAM / オルガネラ間接触 / レドックス / 超硫黄 / 活性酸素種(ROS) / オルガネラ / MITOL/MARCH5 / MITOL / Parkin / パーキンソン病 … More Except Principal Investigator ミトコンドリア Less

Analysis of new molecular pathogenesis of Parkinson's disease focusing on insoluble ParkinPrincipal Investigator
- Principal Investigator
  
  椎葉一心
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gakushuin University
Analysis of the relation between cysteine persulfide regulation mechanism and organelle contact sitesPrincipal Investigator
- Principal Investigator
  
  椎葉一心
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Gakushuin University
ミトコンドリア膜上のユビキチン修飾の役割と病態解明
- Principal Investigator
  
  柳茂
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gakushuin University
Analysis of newly molecular pathogenesis of Parkinson's disease focusing on insolubilization of causal proteinsPrincipal Investigator
- Principal Investigator
  
  SHIIBA ISSHIN
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gakushuin University
Analysis of cysteine persulfide regulation mechanism via organelle contact sitesPrincipal Investigator
- Principal Investigator
  
  椎葉一心
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Gakushuin University

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Ubiquitin-mediated mitochondrial regulation by MITOL/MARCHF5 at a glance2022
- Author(s)
  Nagashima Shun、Ito Naoki、Shiiba Isshin、Shimura Hiroki、Yanagi Shigeru
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 1 Pages: 1-11
- DOI
  10.1093/jb/mvac092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06179, KAKENHI-PUBLICLY-22H05574, KAKENHI-PROJECT-20H03454
[Journal Article] Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation2022
- Author(s)
  Tokuyama T、Uosaki H、Sugiura A、Nishitai G、Takeda K、Nagashima S、Shiiba I、Ito N、Amo T、Mohri S、Nishimura A、Nishida M、Konno A、Hirai H、Ishido S、Yoshizawa T、Shindo T、Takada S、Kinugawa S、Inatome R、Yanagi S
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 7 Pages: 104582-104582
- DOI
  10.1016/j.isci.2022.104582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07878, KAKENHI-PROJECT-21K06844, KAKENHI-PROJECT-22K19754, KAKENHI-PROJECT-22K15399, KAKENHI-PROJECT-19KK0219, KAKENHI-PLANNED-21H05269, KAKENHI-PUBLICLY-22H05574, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20H03454, KAKENHI-PROJECT-21H03360, KAKENHI-PROJECT-19K06899, KAKENHI-PROJECT-19K22791, KAKENHI-PROJECT-23K24334, KAKENHI-PROJECT-22K06454
[Journal Article] MITOL regulates phosphatidic acid-binding activity of RMDN3/PTPIP512022
- Author(s)
  Ito Naoki、Takahashi Takara、Shiiba Isshin、Nagashima Shun、Inatome Ryoko、Yanagi Shigeru
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 171 Issue: 5 Pages: 529-541
- DOI
  10.1093/jb/mvab153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04911, KAKENHI-PROJECT-21K06844, KAKENHI-PROJECT-22K15399, KAKENHI-PUBLICLY-22H05574, KAKENHI-PROJECT-20H03454
[Presentation] The Development of Organelle Contact Sites Quantification Tool and Exploration of the New Role of ER-Mitochondria Contact2024
- Author(s)
  Isshin Shiiba
- Organizer
  Keystone Symposia (Organelle Membrane Contact Sites in Health and Disease)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15399
[Presentation] The Development of Organelle Contact Sites Quantification Tool and Exploration of the New Role of ER-Mitochondria Contact2024
- Author(s)
  Isshin Shiiba
- Organizer
  Keystone Symposia (Organelle Membrane Contact Sites in Health and Disease)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05574
[Presentation] The development of organelle contact sites quantification tool and exploration of the new role of haraguroER-mitochondria contact sites2023
- Author(s)
  Isshin Shiiba
- Organizer
  YU-COE(C) Intracellular Iron Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05574
[Presentation] he development of organelle contact sites quantification tool and exploration of the new role of haraguroER-mitochondria contact sites2023
- Author(s)
  1.Isshin Shiiba
- Organizer
  YU-COE(C) Intracellular Iron Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15399
[Presentation] The regulatory mechanism of mitochondrial iron supply at the MAM2022
- Author(s)
  Isshin Shiiba, Hijiri Oshio, Naoki Ito, Shigeru Yanagi
- Organizer
  Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease, AWAJI, JAPAN
- Data Source
  KAKENHI-PUBLICLY-22H05574
[Presentation] The regulatory mechanism of iron supply to mitochondria at the ER-mitochondria contact site2022
- Author(s)
  Isshin Shiiba, Hijiri Oshio, Naoki Ito, Shigeru Yanagi
- Organizer
  Redox Week in Sendai 2022
- Data Source
  KAKENHI-PUBLICLY-22H05574

1. 柳茂 (60252003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. AMO Taku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 長島駿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIIBA ISSHIN 椎葉 一心

Research Projects

Research Products

Co-Researchers

Analysis of new molecular pathogenesis of Parkinson's disease focusing on insoluble ParkinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the relation between cysteine persulfide regulation mechanism and organelle contact sitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミトコンドリア膜上のユビキチン修飾の役割と病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of newly molecular pathogenesis of Parkinson's disease focusing on insolubilization of causal proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of cysteine persulfide regulation mechanism via organelle contact sitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Ubiquitin-mediated mitochondrial regulation by MITOL/MARCHF5 at a glance2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MITOL regulates phosphatidic acid-binding activity of RMDN3/PTPIP512022

Author(s)

Journal Title

DOI

Data Source

[Presentation] The Development of Organelle Contact Sites Quantification Tool and Exploration of the New Role of ER-Mitochondria Contact2024

Author(s)

Organizer

Data Source

[Presentation] The Development of Organelle Contact Sites Quantification Tool and Exploration of the New Role of ER-Mitochondria Contact2024

Author(s)

Organizer

Data Source

[Presentation] The development of organelle contact sites quantification tool and exploration of the new role of haraguroER-mitochondria contact sites2023

Author(s)

Organizer

Data Source

[Presentation] he development of organelle contact sites quantification tool and exploration of the new role of haraguroER-mitochondria contact sites2023

Author(s)

Organizer

Data Source

[Presentation] The regulatory mechanism of mitochondrial iron supply at the MAM2022

Author(s)

Organizer

Data Source

[Presentation] The regulatory mechanism of iron supply to mitochondria at the ER-mitochondria contact site2022

Author(s)

Organizer

Data Source

SHIIBA ISSHIN 椎葉一心