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Takeoka Yoshiki  武岡 由樹

ORCIDConnect your ORCID iD *help
Researcher Number 30943592
Other IDs
Affiliation (Current) 2026: 神戸大学, 医学系研究科(医), 特命助教
Affiliation (based on the past Project Information) *help 2023 – 2025: 神戸大学, 医学研究科, 特命助教
2022: 神戸大学, 医学部附属病院, 特命助教
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related
Except Principal Investigator
Basic Section 56020:Orthopedics-related
Keywords
Principal Investigator
細胞外基質 / オートファジー / TRPV4 / 脊椎椎間板 / 椎間板変性 / 細胞外基質代謝 / ラット尾椎椎間板 / 椎間板髄核細胞
Except Principal Investigator
シルクエラスチン / 人工髄核 … More / 椎間板再生 / 腰痛 / AdipoRon / 抗炎症作用 / 椎間板 / 椎間板変性 / アディポネクチン / アディポロン / 抗炎症 Less
  • Research Projects

    (4 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (7 People)
  •  Research on a treatment system for degenerative intervertebral discs using silk elastin - Attempts to create artificial intervertebral discs -

    • Principal Investigator
      角谷 賢一朗
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kobe University
  •  メカノレセプターTRPV4を介した椎間板内恒常性維持機構の解明Principal Investigator

    • Principal Investigator
      武岡 由樹
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kobe University
  •  アディポネクチンによる椎間板変性・炎症に対する治療法の開発

    • Principal Investigator
      張 鍾穎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kobe University
  •  Therapeutic approach for intervertebral disc degeneration by modulating the mechanoreceptor of TRPV4Principal Investigator

    • Principal Investigator
      Takeoka Yoshiki
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kobe University

All 2025 2024 2023

All Journal Article Presentation

  • [Journal Article] Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc2025

    • Author(s)
      Matsuo Tomoya、Takeoka Yoshiki、Yurube Takashi、Tsujimoto Takeru、Kanda Yutaro、Miyazaki Kunihiko、Ohnishi Hiroki、Ryu Masao、Kumagai Naotoshi、Kuroshima Kohei、Hiranaka Yoshiaki、Kuroda Ryosuke、Kakutani Kenichiro
    • Journal Title

      JOR SPINE

      Volume: 8 Issue: 1

    • DOI

      10.1002/jsp2.70046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) knockdown decreases extracellular matrix synthesis via autophagy suppression in rat intervertebral disc2024

    • Author(s)
      Tomoya Matsuo, Yoshiki Takeoka, Takashi Yurube, Takeru Tsujimoto, Yutaro Kanda, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Naotoshi Kumagai, Kohei Kuroshima, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      The 70th Annual Meeting, Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] 椎間板のTransient Receptor Potential Vanilloid 4阻害によるオートファジー活性と細胞外基質合成の抑制2024

    • Author(s)
      松尾 智哉, 武岡 由樹, 由留部 崇, 辻本 武尊, 角谷 賢一朗, 黒田 良祐
    • Organizer
      第143回中部日本整形外科災害外科学会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Agonist-induced activation of Transient Receptor Potential Vanilloid 4 promotes autophagy and extracellular matrix synthesis through AMPK pathway in rat intervertebral disc2024

    • Author(s)
      Kuroshima K, Takeoka Y, Yurube T, Tsujimoto T, Kanda Y, Miyazaki K, Ohnishi H, Matsuo T, Ryu M, Kumagai N, Hiranaka Y, Kuroda R, Kakutani K
    • Organizer
      50th Annual Meeting, International Society for the Study of the Lumbar Spine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) knockdown decreases matrix synthesis by diminishing autophagy in rat intervertebral disc2024

    • Author(s)
      Matsuo T, Takeoka Y, Yurube T, Kumagai N, Kanda Y, Tsujimoto T, Ohnishi H, Ryu M, Kuroshima K, Hiranaka Y, Miyazaki K, Kuroda R, Kakutani K
    • Organizer
      50th Annual Meeting, International Society for the Study of the Lumbar Spine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) knockdown decreases matrix synthesis via autophagy suppression in rat intervertebral disc2024

    • Author(s)
      松尾智哉,武岡由樹,由留部崇,辻本武尊,神田裕太郎,大西洋輝,劉正夫,熊谷直利,黒島康平,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第53回日本脊椎脊髄病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Agonist-induced Activation Of Transient Receptor Potential Vanilloid 4 Promotes Autophagy And Extracellular Matrix Synthesis Via Ampk Pathway In Rat Intervertebral Disc2024

    • Author(s)
      Kohei Kuroshima; Yoshiki Takeoka; Takashi Yurube; Takeru Tsujimoto; Yutaro Kanda; Kunihiko Miyazaki; Tomoya Matsuo; Masao Ryu; Naotoshi Kumagai; Yoshiaki Hiranaka; Masahiko Furuya; Daisuke Nakagawa; Yu Inoue; Ryosuke Kuroda; Kenichiro Kakutani
    • Organizer
      2025 Annual Meeting, Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Suppression Of Transient Receptor Potential Vanilloid 4 (trpv4) Decelerates Extracellular Matrix Synthesis By Inhibiting Autophagy In The Rat Intervertebral Disc2024

    • Author(s)
      Tomoya Matsuo; Yoshiki Takeoka; Takashi Yurube; Takeru Tsujimoto; Yutaro Kanda; Kunihiko Miyazaki; Masao Ryu; Naotoshi Kumagai; Kohei Kuroshima; Yoshiaki Hiranaka; Daisuke Nakagawa; Masahiko Furuya; Yu Inoue; Kenichiro Kakutani; Ryosuke Kuroda
    • Organizer
      2025 Annual Meeting, Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4(TRPV4)活性化はラット椎間板のオートファジーと細胞外基質合成を促進する2024

    • Author(s)
      黒島康平,武岡由樹,由留部崇,辻本武尊,神田裕太郎,松尾智哉,劉正夫,熊谷直利,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第39回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] ラット椎間板におけるtransient receptor potential vanilloid 4(TRPV4)阻害がオートファジーと細胞外基質合成を抑制する2024

    • Author(s)
      松尾 智哉, 武岡 由樹, 由留部 崇, 辻本 武尊,神田 裕太郎, 劉 正夫, 熊谷 直利, 黒島 康平, 平中 良明, 黒田 良祐, 角谷 賢一朗
    • Organizer
      第39回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 activation promotes autophagy and extracellular matrix synthesis in the rat intervertebral disc2024

    • Author(s)
      黒島康平,武岡由樹,由留部崇,辻本武尊,神田裕太郎,大西洋輝,松尾智哉,劉正夫,熊谷直利,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第53回日本脊椎脊髄病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) activation by agonist promotes autophagy and extracellular matrix synthesis through AMPK pathway in rat intervertebral disc2024

    • Author(s)
      Kohei Kuroshima, Yoshiki Takeoka, Takashi Yurube, Takeru Tsujimoto, Yutaro Kanda, Kunihiko Miyazaki, Hiroki Ohnishi, Tomoya Matsuo, Masao Ryu, Naotoshi Kumagai, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      The 70th Annual Meeting, Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] ラット椎間板においてTransient Receptor Potential Vanilloid 4 (TRPV4)がオートファジーと細胞外マトリクス合成へ与える影響2023

    • Author(s)
      松尾智哉, 武岡由樹, 張鍾穎, 由留部崇, 宮崎邦彦, 大西洋輝, 劉正夫, 熊谷直利, 黒島康平, 平中良明, 黒田良祐, 角谷賢一朗
    • Organizer
      第52回日本脊椎脊髄病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) knockdown decreases extracellular matrix synthesis via autophagy suppression in rat intervertebral disc2023

    • Author(s)
      Tomoya Matsuo, Yoshiki Takeoka, Zhongying Zhang, Takashi Yurube, Yuji Kakiuchi, Yutaro Kanda, Ryu Tsujimoto, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Naotoshi Kumagai, Yoshiaki Hiranaka, Kohei Kuroshima, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      SpineWeek 2023 (the International Society for the Study of the Lumbar Spine)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) activation promotes autophagy and increases extracellular matrix synthesis through AMPK pathway in rat intervertebral disc cells2023

    • Author(s)
      Kohei Kuroshima, YoshikiTakeoka, Zhongying Zhang, Takashi Yurube, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Tomoya Matsuo, Naotoshi Kumagai, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      SpineWeek 2023 (the International Society for the Study of the Lumbar Spine)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) knockdown decreases extracellular matrix synthesis via autophagy suppression in rat intervertebral disc2023

    • Author(s)
      Tomoya Matsuo, Yoshiki Takeoka, Zhongying Zhang, Takashi Yurube, Yuji Kakiuchi, Yutaro Kanda, Ryu Tsujimoto, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Naotoshi Kumagai, Yoshiaki Hiranaka, Kohei Kuroshima, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      SpineWeek 2023 (the International Society for the Study of the Lumbar Spine)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) activation promotes autophagy and increases extracellular matrix synthesis through AMPK pathway in rat intervertebral disc cells2023

    • Author(s)
      Kohei Kuroshima, YoshikiTakeoka, Zhongying Zhang, Takashi Yurube, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Tomoya Matsuo, Naotoshi Kumagai, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      SpineWeek 2023 (the International Society for the Study of the Lumbar Spine)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4)活性化によるラット椎間板髄核細胞のオートファジーと細胞外基質合成の促進2023

    • Author(s)
      黒島康平,武岡由樹,張鍾穎,由留部崇,宮﨑邦彦,大西洋輝,劉正夫,松尾智哉,熊谷直利,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第52回日本脊椎脊髄病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] ラット椎間板においてメカノレセプターTRPV4が恒常性維持と細胞外基質代謝に果たす役割2023

    • Author(s)
      武岡由樹,松尾智哉,由留部崇,辻本武尊,神田裕太郎,宮崎邦彦,大西洋輝,劉正夫,熊谷直利,黒島康平,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第31回日本腰痛学会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] ラット椎間板においてTransient Receptor Potential Vanilloid 4 (TRPV4)がオートファジーと細胞外マトリクス合成へ与える影響2023

    • Author(s)
      松尾智哉,武岡由樹,張鍾穎,由留部崇,宮崎邦彦,大西洋輝,劉正夫,熊谷直利,黒島康平,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第52回日本脊椎脊髄病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] ラット椎間板におけるTransient Receptor Potential Vanilloid 4 (TRPV4)阻害はオートファジーと細胞外基質合成を抑制する2023

    • Author(s)
      松尾智哉, 武岡由樹, 由留部崇, 宮崎邦彦, 大西洋輝 ,劉正夫, 熊谷直利, 黒島康平, 平中良明, 黒田良祐, 角谷賢一朗
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] eceptor Potential Vanilloid 4 (TRPV4)活性化によるラット椎間板髄核細胞のオートファジーと細胞外基質合成の促進2023

    • Author(s)
      黒島康平,武岡由樹,張鍾穎,由留部崇,宮﨑邦彦,大西洋輝,劉正夫,松尾智哉,熊谷直利,平中良明,黒田良祐,角谷賢一朗
    • Organizer
      第52回日本脊椎脊髄病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4) knockdown decreases extracellular matrix synthesis via autophagy suppression in rat intervertebral disc2023

    • Author(s)
      Tomoya Matsuo, Yoshiki Takeoka, Zhongying Zhang, Takashi Yurube, Kunihiko Miyazaki, Hiroki Ohnishi, Masao Ryu, Naotoshi Kumagai, Kohei Kuroshima, Yoshiaki Hiranaka, Ryosuke Kuroda, Kenichiro Kakutani
    • Organizer
      69th Annual Meeting, Orthopaedic Research Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16743
  • [Presentation] Transient Receptor Potential Vanilloid 4 (TRPV4)活性化によるラット椎間板髄核細胞のオートファジーと細胞外基質合成の促進2023

    • Author(s)
      黒島康平: 武岡由樹: 由留部崇: 宮﨑邦彦: 大西洋輝: 松尾智哉: 劉正夫: 熊谷直利: 平中良明: 黒田良祐 :角谷賢一朗
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K16743
  • 1.  由留部 崇 (10514648)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  角谷 賢一朗 (10533739)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  神田 裕太郎 (51010524)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  辻本 武尊 (00823337)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  張 鍾穎 (00824195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  田畑 泰彦 (50211371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  西田 英高 (00622804)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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