Harada Akikazu 原田昭和

… Alternative Names

HARADA Akikazu 原田昭和

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Researcher Number	30963350
Other IDs
Affiliation (Current)	2026: 群馬大学, 未来先端研究機構, 講師
Affiliation (based on the past Project Information) *help	2023 – 2026: 大阪大学, 感染症総合教育研究拠点, 特任助教(常勤) 2022 – 2023: 大阪大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields Except Principal Investigator Medium-sized Section 50:Oncology and related fields / Basic Section 57040:Regenerative dentistry and dental engineering-related
Keywords	Principal Investigator がん / Wntシグナル / 神経芽腫 / GREB1 / 遺伝子発現制御 / 小児がん Except Principal Investigator Wnt / 幹細胞 / 唾液腺 / DKK1-CKAP4シグナル … More / 非細胞自律性機構 / がん免疫 / 炎症 / 血管内皮細胞 / 1細胞RNAシーケンス / がん微小環境 / 低酸素 / 一細胞RNAシーケンス / 大腸がん / 線維芽細胞 / Wnt5a Less

核内受容体制御因子GREB1を介した神経芽腫の悪性系譜誘導機構の解明Principal Investigator
- Principal Investigator
  
  原田昭和
- Project Period (FY)
  2026 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Osaka
Mechanism of Cancer Immune Escape by the Non-Cell Autonomous DKK1-CKAP4 Signaling Pathway
- Principal Investigator
  
  菊池章
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Osaka
Elucidation of the Function of Embryonic-Like Revertant Stem Cells in Salivary Gland Repair and Establishment of a Basis for Regenerative Therapy
- Principal Investigator
  
  松本真司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  The University of Tokushima
Wntシグナルが駆動するがん種特異的な増殖機構制御因子の探索Principal Investigator
- Principal Investigator
  
  原田昭和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University
Unraveling the Heterogeneity of Cancer-Associated Fibroblasts through Intercellular Signaling
- Principal Investigator
  
  Kikuchi Akira
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Osaka University
GREB1-signaling in promoting tumorigenesis of pediatric cancerPrincipal Investigator
- Principal Investigator
  
  HARADA Akikazu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Osaka University

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression2025
- Author(s)
  Akikazu Harada, Yoshiaki Yasumizu, Takeshi Harada, Katsumi Fumoto, Akira Sato, Natsumi Maehara, Ryota Sada, Shinji Matsumoto, Takashi Nishina, Kiyoshi Takeda, Eiichi Morii, Hisako Kayama, Akira Kikuchi
- Journal Title
  
  Nature Communications
  
  Volume: 16 Issue: 1 Pages: 3653-3653
- DOI
  10.1038/s41467-025-58748-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-23K18241, KAKENHI-PROJECT-23K14566
[Journal Article] Newly developed humanized anti‐CKAP4 antibody suppresses pancreatic cancer growth by inhibiting DKK1‐CKAP4 signaling2024
- Author(s)
  Ryota Sada, Hideki Yamamoto, Shinji Matsumoto, Akikazu Harada, Akira Kikuchi
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 10 Pages: 3358-3369
- DOI
  10.1111/cas.16278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K18241, KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-24K11110, KAKENHI-PROJECT-23K14566
[Journal Article] Hypoxia drives the formation of lung micropapillary adenocarcinoma-like structure through hypoxia-inducible factor-1α2024
- Author(s)
  Umeda Daisuke、Harada Akikazu、Motooka Daisuke、Tahara Shinichiro、Kurashige Masako、Kido Kansuke、Takashima Tsuyoshi、Kiyokawa Hiroki、Ukon Koto、Matsui Takahiro、Matsumoto Shinji、Shintani Yasushi、Okuzaki Daisuke、Kikuchi Akira、Nojima Satoshi、Morii Eiichi
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 31642-31642
- DOI
  10.1038/s41598-024-80280-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19433, KAKENHI-PROJECT-23K18241, KAKENHI-PROJECT-23K27391, KAKENHI-PROJECT-23K27671, KAKENHI-PROJECT-23K06461, KAKENHI-PROJECT-24K10285, KAKENHI-PROJECT-23K14566
[Presentation] Wnt5a発現線維芽細胞による大腸がん増殖機構の解明2024
- Author(s)
  原田昭和、菊池章
- Organizer
  第83回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K14566
[Presentation] Wnt5a 発現線維芽細胞による大腸がん増殖機構の解明2024
- Author(s)
  原田昭和, 菊池章
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K18241
[Presentation] 大腸がんにおける腫瘍環境特異的がん関連線維芽細胞の実体とその制御2023
- Author(s)
  原田昭和、菊池章
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K18241
[Presentation] Gene regulation program for proliferation and differentiation in Wnt signal-activated liver and colon cancer2023
- Author(s)
  Akira Kikuchi, Shinji Matsumoto, Akikazu Harada
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18241

1. Kikuchi Akira (10204827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 佐田遼太 (60869783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松本真司 (20572324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 姚陳娟 (20432750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 森井英一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Harada Akikazu 原田 昭和

HARADA Akikazu 原田 昭和

Research Projects

Research Products

Co-Researchers

核内受容体制御因子GREB1を介した神経芽腫の悪性系譜誘導機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of Cancer Immune Escape by the Non-Cell Autonomous DKK1-CKAP4 Signaling Pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Function of Embryonic-Like Revertant Stem Cells in Salivary Gland Repair and Establishment of a Basis for Regenerative Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Wntシグナルが駆動するがん種特異的な増殖機構制御因子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Unraveling the Heterogeneity of Cancer-Associated Fibroblasts through Intercellular Signaling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

GREB1-signaling in promoting tumorigenesis of pediatric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Newly developed humanized anti‐CKAP4 antibody suppresses pancreatic cancer growth by inhibiting DKK1‐CKAP4 signaling2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypoxia drives the formation of lung micropapillary adenocarcinoma-like structure through hypoxia-inducible factor-1α2024

Author(s)

Journal Title

DOI

Data Source

[Presentation] Wnt5a発現線維芽細胞による大腸がん増殖機構の解明2024

Author(s)

Organizer

Data Source

[Presentation] Wnt5a 発現線維芽細胞による大腸がん増殖機構の解明2024

Author(s)

Organizer

Data Source

[Presentation] 大腸がんにおける腫瘍環境特異的がん関連線維芽細胞の実体とその制御2023

Author(s)

Organizer

Data Source

[Presentation] Gene regulation program for proliferation and differentiation in Wnt signal-activated liver and colon cancer2023

Author(s)

Organizer

Data Source

Harada Akikazu 原田昭和

HARADA Akikazu 原田昭和