Omura Issei 大村翼世

Researcher Number	30981261
Affiliation (Current)	2025: 金沢大学, 医学系, 助教
Affiliation (based on the past Project Information) *help	2024: 金沢大学, 医学系, 助教 2023: 広島大学, 医系科学研究科(医), 研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields
Keywords	Principal Investigator エピジェネティクス / セラミド / 翻訳後修飾 / OASIS / がん / 細胞周期 / メチル化 / 癌 / 小胞体ストレス

Establishment of a foundation for novel cancer therapies targeting abnormal epigenomic modifications that lead to dysregulation of cell cyclePrincipal Investigator
- Principal Investigator
  
  大村翼世
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Elucidation of the tumor suppression mechanism by OASIS and establishment of the basis for new treatmentsPrincipal Investigator
- Principal Investigator
  
  Omura Issei
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kanazawa University
  Hiroshima University

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Unfolded protein response modulates Tyrosinase levels and melanin production during melanogenesis2025
- Author(s)
  Yamazaki Akari、Omura Issei、Kamikawa Yasunao、Hide Michihiro、Tanaka Akio、Kaneko Masayuki、Imaizumi Kazunori、Saito Atsushi
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 117 Issue: 2 Pages: 36-44
- DOI
  10.1016/j.jdermsci.2025.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19541, KAKENHI-PROJECT-24KJ1726, KAKENHI-PROJECT-24K18486
[Journal Article] VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma2024
- Author(s)
  Wu Zuqian、Omura Issei、Saito Atsushi、Imaizumi Kazunori、Kamikawa Yasunao
- Journal Title
  
  Nucleus
  
  Volume: 15 Issue: 1 Pages: 1-18
- DOI
  10.1080/19491034.2024.2423660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06129, KAKENHI-PROJECT-23K19541, KAKENHI-PROJECT-23K17413, KAKENHI-PROJECT-24K18486
[Journal Article] CREB3L1/OASIS: cell cycle regulator and tumor suppressor2024
- Author(s)
  Saito Atsushi、Omura Issei、Imaizumi Kazunori
- Journal Title
  
  The FEBS Journal
  
  Volume: 291 Issue: 22 Pages: 4853-4866
- DOI
  10.1111/febs.17052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19541, KAKENHI-PROJECT-23K17413, KAKENHI-PROJECT-24K18486
[Presentation] 小胞体膜局在分子の新たな活性化システムと核膜の恒常性制御2024
- Author(s)
  齋藤敦, 大村翼世, 今泉和則
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K19541
[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理学的意義の解明2024
- Author(s)
  大村翼世, 齋藤敦, 今泉和則
- Organizer
  第76回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-23K19541
[Presentation] 膜脂質セラミドを介した小胞体膜局在転写因子OASISの活性制御機構2024
- Author(s)
  大村翼世, 齋藤敦
- Organizer
  金沢大学第15回ライフサイエンス研究交流セミナー
- Data Source
  KAKENHI-PROJECT-23K19541
[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断制御機構2024
- Author(s)
  大村翼世, 今泉和則, 齋藤敦
- Organizer
  第97回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-24K18486
[Presentation] 膜脂質セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理的意義の解明2024
- Author(s)
  大村翼世, 齋藤敦, 今泉和則
- Organizer
  第65回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-23K19541
[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理学的意義の解明2024
- Author(s)
  大村翼世, 齋藤敦, 今泉和則
- Organizer
  第76回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-24K18486
[Presentation] 膜脂質セラミドを介した小胞体膜局在転写因子OASISの活性制御機構2024
- Author(s)
  大村翼世, 齋藤敦
- Organizer
  金沢大学第15回ライフサイエンス研究交流セミナー
- Data Source
  KAKENHI-PROJECT-24K18486
[Presentation] 小胞体膜局在分子の新たな活性化システムと核膜の恒常性制御2024
- Author(s)
  齋藤敦, 大村翼世, 今泉和則
- Organizer
  第97回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-24K18486
[Presentation] 膜脂質セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理的意義の解明2024
- Author(s)
  大村翼世, 齋藤敦, 今泉和則
- Organizer
  第65回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-24K18486
[Presentation] セラミドによる小胞体膜局在転写因子 OASISの活性制御機構の解明2024
- Author(s)
  大村翼世, 今泉和則, 齋藤敦
- Organizer
  第17回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-23K19541
[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断制御機構2024
- Author(s)
  大村翼世, 今泉和則, 齋藤敦
- Organizer
  第97回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K19541
[Presentation] セラミドによる小胞体膜局在転写因子 OASISの活性制御機構の解明2024
- Author(s)
  大村翼世, 今泉和則, 齋藤敦
- Organizer
  第17回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-24K18486
[Presentation] Cell-specific regulation of cell cycle arrest by endoplasmic reticulum-resident transcription factor OASIS via p21 induction.2023
- Author(s)
  Atsushi Saito, Yasunao Kamikawa, Issei Omura, Kazunori Imaizumi
- Organizer
  American Society for Cell Biology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19541

1. 上川泰直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Omura Issei 大村 翼世

Research Projects

Research Products

Co-Researchers

Establishment of a foundation for novel cancer therapies targeting abnormal epigenomic modifications that lead to dysregulation of cell cyclePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the tumor suppression mechanism by OASIS and establishment of the basis for new treatmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Unfolded protein response modulates Tyrosinase levels and melanin production during melanogenesis2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CREB3L1/OASIS: cell cycle regulator and tumor suppressor2024

Author(s)

Journal Title

DOI

Data Source

[Presentation] 小胞体膜局在分子の新たな活性化システムと核膜の恒常性制御2024

Author(s)

Organizer

Data Source

[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理学的意義の解明2024

Author(s)

Organizer

Data Source

[Presentation] 膜脂質セラミドを介した小胞体膜局在転写因子OASISの活性制御機構2024

Author(s)

Organizer

Data Source

[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断制御機構2024

Author(s)

Organizer

Data Source

[Presentation] 膜脂質セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理的意義の解明2024

Author(s)

Organizer

Data Source

[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理学的意義の解明2024

Author(s)

Organizer

Data Source

[Presentation] 膜脂質セラミドを介した小胞体膜局在転写因子OASISの活性制御機構2024

Author(s)

Organizer

Data Source

[Presentation] 小胞体膜局在分子の新たな活性化システムと核膜の恒常性制御2024

Author(s)

Organizer

Data Source

[Presentation] 膜脂質セラミドによる小胞体膜局在転写因子OASISの膜内切断活性化機構と生理的意義の解明2024

Author(s)

Organizer

Data Source

[Presentation] セラミドによる小胞体膜局在転写因子 OASISの活性制御機構の解明2024

Author(s)

Organizer

Data Source

[Presentation] セラミドによる小胞体膜局在転写因子OASISの膜内切断制御機構2024

Author(s)

Organizer

Data Source

[Presentation] セラミドによる小胞体膜局在転写因子 OASISの活性制御機構の解明2024

Author(s)

Organizer

Data Source

[Presentation] Cell-specific regulation of cell cycle arrest by endoplasmic reticulum-resident transcription factor OASIS via p21 induction.2023

Omura Issei 大村翼世