NOGUCHI Motoko 野口基子

Researcher Number	40021951
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: 静岡大学, 理学部, 教授 2000 – 2005: 静岡大学, 理学部, 助教授 2004: SHIZUOKA UNIVERSITY, FACULTY OF SCIENCE, PROFESSOR, 理学部, 教授 1987 – 1998: BIOLOGICAL INSTITUTE, FACULTY OF SCIENCE, SHIZUOKA UNIVERSITY, 理学部, 助教授 1986: 静大, 理学部, 講師
Review Section/Research Field	Principal Investigator Laboratory animal science / 動物発生・生理学 / Laboratory animal science
Keywords	Principal Investigator 始原生殖細胞 / マウス / Germ cell deficiency / アポトーシス / Primordial germ cells / ter (teratoma) gene / terコンジェニック系統 / 生殖細胞欠損 / 生殖細胞欠損遺伝子 / ter(teratoma)遺伝子 … More / Apoptosis / Germ-cell growth factor / Mouse embryo / Testicular teratomas / Mouse / Primordial germ cell / 精巣性奇形腫 / ter遺伝子 / 細胞増殖因子 / 再構成精巣 / PTEN / 染色体マッピング / Gonadal somatic cells / ter変異遺伝子 / Conditioned medium / PGC増殖因子 / マウス胚 / ter congenic strain / Teratocarcinogenesis / Reconstituted testis / teratoma(ter) / ter(teratoma) / 奇形腫原因遺伝子 / 生殖細胞培養 / TERF / 発生工学 / Recessive mutant gene / Testcular teratomas / 生殖細胞腫瘍化 / 劣性突然変異遺伝子ter / Sv-ter系統マウス / 精巣性奇形腫高発系統マウス / 劣性突然変異遺伝子teratoma(ter) / Sv-ter系統 / 129 / 精巣性奇形腫形成 / Totipotency / Chromosome mapping / Teratoma candidate / KO mouse / 精子形成 / 精巣性奇形腫(テラトーマ) / 生殖細胞増殖 / 生殖細胞特異遺伝子 / マッピング / 奇形腫(テラトーマ) / 分化全能性 / 遺伝子改変マウス / 奇形腫高発系 / ett1 (experimental testicular teratomas 1) gene / インプリンティング / 原因遺伝子 / 生殖細胞特異抗原 / 胎仔精巣 / テラトーマ原因遺伝子 / 生殖巣体細胞 / ett1(experimental testicular teratomas1) / コンデイションメデイウム / 遺伝子クローニング / 精巣体細胞 / コンデイシヨンドメディウム / 胎仔生殖巣体細胞 / コンディションドメデイウム / PGC欠損 / 増殖因子 / 細胞周期 / 細胞培養 / コンデイションドメディウム / コンジェニックマウス / コンデイションドメデイウム / Terコンジェニック系統 / ter(tevatoma)遺伝子 / 奇形腫形成 / Developmental biotechnology / Gene mapping / Sterility / The ter(teratoma) gene / 再構成生殖巣 / 精巣性テラトーマ / リンケージマッピング / 発生工学的解析 / 不妊モデル / 貧血 / 不妊 / 奇形腫高発系マウス / 生殖細胞増殖因子 / 遺伝子 / 幹細胞増殖因子 / 単為発生卵 / 生殖細胞 / コンジェニック系統 / 卵巣性奇形腫 / 奇形腫(テラトーマ)高発系マウス / コンデイションドメデイウム / SLF / コンディションドメディウム / ミニサテライトDNA … More Except Principal Investigator 癌遺伝子 / 形質転換動物 / 再構成卵巣 / 体外受精 / 哺乳動物初期胚 / チミヂンキナーゼ遺伝子 / グロビン / F9細胞 / 胚の分化と増殖 / 胚割球の分離 / 体外培養 / カニクイザル / 相同的組替え / 胚培養 / 核移植 / 遺伝子導入動物 / 胚奇形腫 / 始原生植細胞 / 分化遺伝子 / マウス / ウシ / サル / テラト-マ / キメラ / インターフェロン遺伝子 / 成長ホルモン遺伝子 / 共培養 Less

生殖細胞を起源とする奇形腫の多因子モデルマウスの育成と解析Principal Investigator
- Principal Investigator
  
  野口基子
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Shizuoka University
GENETIC AND DEVELOPMENTAL ANALYSIS OF MECHANISMS UNDERLYING TERATOCARCINOGENESIS IN THE MOUSE GERM CELLS.Principal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shizuoka University
GENETICS AND DEVELOPMENTAL BIOLOGICAL ANALYSIS OF MECHANISMS INDUCING TESTICULAR TERATOCARCINOGENESIS IN PRIMORDIAL GERM CELLS IN MICEPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  SHIZUOKA UNIVERSITY
マウスの新規な始原生殖細胞増殖因子TERFの単離,同定及び機能解析Principal Investigator
- Principal Investigator
  
  野口基子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Shizuoka University
マウスの新規な始原生殖細胞増殖因子の単離、同定及び機能解析Principal Investigator
- Principal Investigator
  
  野口基子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shizuoka University
FUNCTION OF THE ter MUTATION AND MOLECULAR CHARACTERISTCS OF A NOVEL PRIMORDIAL GERM CELL GROWTH FACTOR (TERF) IN MICEPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C).
- Research Field
  
  Laboratory animal science
- Research Institution
  SHIZUOKA UNIVERSITY
CELL BIOLOGICAL AND BIOCHEMICAL STUDIES ON FUNCTION OF THE ter GENE IN PRIMORDIAL GERM CELL DEFICIENCY IN ter MUTANT MICE.Principal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  SHIZUOKA UNIVERSITY
マウスの始原生殖細胞の増殖と分化を制御するter遺伝子の機能解析Principal Investigator
- Principal Investigator
  
  野口基子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shizuoka University
DEVELOPMENTAL BIOLOGICAL STUDIES ON FUNCTION OF THE ter GENEIN DEFICIENCY AND TERATOCARCINOGENESIS OF PRIMORDIAL GERM CELLS IN ter MUTANT MICEPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shizuoka University
初期発生における割球分化の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
MAPPING AND DEVELOPMENTAL BIOTECHNOLOGY OF THE ter GENE RESPONSIBLE FOR GERM CELL DEFICIENCY IN MICE.Principal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  SHIZUOKA UNIVERSITY
初期発生における割球分化の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
初期発生の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
初期発生の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
DEVELOPMENTAL GENETICS IN TESTICULAR TERATOCARCINOGENESIS AND GERM CELL DEFICIENCY CAUSED BY THE GENE ter IN MICE.Principal Investigator
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  動物発生・生理学
- Research Institution
  SHIZUOKA UNIVERSITY

All 2001 2000

All Journal Article

[Journal Article] The ter/ter gonadal somatic cells cause apoptosis in ter/ter primordial germ cells (PGCs) with normal survivability and proliferation ability in the mouse : Evidence from PGC-somatic cell "exchange-co-culture".2001
- Author(s)
  Takabayashi, S., Nozaki, M., Ishikawa, K.Noguchi, M.
- Journal Title
  
  Zoological Science 18(5)
  
  Pages: 695-704
- NAID
  110003371974
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] Novel growth factor supporting survival of murine primordial germ cells : Evidence from conditioned medium of ter fetal gonadal somatic cells.2001
- Author(s)
  Takabayashi, S., Sasaoka, Y., Yamashita, M., Tokumoto, T., Ishikawa, K., Noguchi, M.
- Journal Title
  
  Molecular Reproduction and Development 60(3)
  
  Pages: 384-396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] Novel growth factor supporting survival of murine primordial germ cells : Evidence from conditioned medium of ter fetal gonadal somatic cells.2001
- Author(s)
  Takabayashi, S., Sasaoka, Y., Yamashita, M., Tokumoto, T., Ishikawa, K., Noguchi, M.
- Journal Title
  
  Molecular Reproduction and Development 60
  
  Pages: 384-396
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] The ter/ter gonadal somatic cells cause apoptosis in ter/ter primordial germ cells (PGCs) with normal survivability and proliferation ability in the mouse : Evidence from PGC-somatic cell "exchange-co-culture".2001
- Author(s)
  Takabayashi, S., Nozaki, M., Ishikawa, K., Noguchi, M.
- Journal Title
  
  Zoological Science 18
  
  Pages: 695-704
- NAID
  110003371974
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development.2000
- Author(s)
  Ueda, T., Abe, K., Miura, A., Yuzuriha, M., Zubair, M., Noguchi, M., Niwa, K., Kawase, Y., Kono, T., Matsuda, Y., Fujimoto, H., Shibata, H., Hayashizaki, Y., Sasaki, H.
- Journal Title
  
  Genes to Cells 5(8)
  
  Pages: 649-659
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development.2000
- Author(s)
  Ueda, T., Abe, K., Miura, A., Noguchi, M., Sasaki, H.et al.
- Journal Title
  
  Genes to Cells 5
  
  Pages: 649-659
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] Testicular somatic cells are responsible for experimental teratocarcinogenesis of primordial gene cells in reconstituted mouse testes.2000
- Author(s)
  Noguchi, M., Niwa, K., Kasai, T., Tsunesada, M., Sasaoka, Y., Kusakabe, M.
- Journal Title
  
  Journal of Reproduction and Development 46(Supplement)
  
  Pages: 71-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] Testicular somatic cells are responsible for experimental terato-carcinogenesis of primordial germ cells in reconstituted testes.2000
- Author(s)
  Noguchi, M., Niwa, K., Kasai, T., Tsunesada, M., Sasaoka, Y., Kusakabe, M.
- Journal Title
  
  Journal of Reproduction and Development 46
  
  Pages: 71-72
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680809

1. TOKUMOTO Toshinobu (30273163)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. 岩倉洋一朗 (10089120)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 入谷明 (80026385)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 帯刀益夫 (10099971)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 山内一也 (30072888)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 畑中正一 (30142300)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. NOZAKI Masami (30189394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KIMURA Tohru (50280962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NOGUCHI Motoko 野口 基子

Research Projects

Research Products

Co-Researchers

生殖細胞を起源とする奇形腫の多因子モデルマウスの育成と解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GENETIC AND DEVELOPMENTAL ANALYSIS OF MECHANISMS UNDERLYING TERATOCARCINOGENESIS IN THE MOUSE GERM CELLS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GENETICS AND DEVELOPMENTAL BIOLOGICAL ANALYSIS OF MECHANISMS INDUCING TESTICULAR TERATOCARCINOGENESIS IN PRIMORDIAL GERM CELLS IN MICEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マウスの新規な始原生殖細胞増殖因子TERFの単離,同定及び機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

マウスの新規な始原生殖細胞増殖因子の単離、同定及び機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

FUNCTION OF THE ter MUTATION AND MOLECULAR CHARACTERISTCS OF A NOVEL PRIMORDIAL GERM CELL GROWTH FACTOR (TERF) IN MICEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CELL BIOLOGICAL AND BIOCHEMICAL STUDIES ON FUNCTION OF THE ter GENE IN PRIMORDIAL GERM CELL DEFICIENCY IN ter MUTANT MICE.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マウスの始原生殖細胞の増殖と分化を制御するter遺伝子の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

DEVELOPMENTAL BIOLOGICAL STUDIES ON FUNCTION OF THE ter GENEIN DEFICIENCY AND TERATOCARCINOGENESIS OF PRIMORDIAL GERM CELLS IN ter MUTANT MICEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

初期発生における割球分化の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

MAPPING AND DEVELOPMENTAL BIOTECHNOLOGY OF THE ter GENE RESPONSIBLE FOR GERM CELL DEFICIENCY IN MICE.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

初期発生における割球分化の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

初期発生の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

初期発生の分子機構

Principal Investigator

Project Period (FY)

Research Category

NOGUCHI Motoko 野口基子