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MATSUO Osamu  松尾 理

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Researcher Number 40030879
Other IDs
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Affiliation *help 2013 : 近畿大学, 医学部, 名誉教授
2013 : 近畿大学, 医学部, 教授
2011 – 2013 : 近畿大学, 医学部, 顧問
2011 – 2012 : 近畿大学, 医学部, その他
2011 : 近畿大学, 医学部, 名誉教授 … More
1994 – 2011 : 近畿大学, 医学部, 教授
1996 – 2008 : 近畿大, 医学部, 教授
2007 : 近畿大学, 医学部, 顧問
1991 – 1992 : 近畿大学, 医学部, 教授
1986 : 近大, 医学部, 教授 Less
Review Section/Research Field
Principal Investigator
General physiology / General physiology / Hematology
Except Principal Investigator
General physiology / Biomedical engineering/Biological material science / General physiology / Environmental physiology (including Physical medicine and Nutritional physiology) / Cerebral neurosurgery
Keywords
Principal Investigator
t-PA / u-PA / 血管内皮細胞 / 血管新生 / PAI-1 / 線溶系 / t-PA受容体 / フィブリン / 線溶系因子欠損マウス / fibrin … More / u-PAR / 組織修復 / plasminogen / MMP-2 / 血管平滑筋細胞 / 蛋白分解活性 / カプセル / ノックアウトマウス / angiogenesis / t-PAR system / 遺伝子発現 / t-pA / gene expression regulation / Capsule / ES細胞 / vascular smooth muscle cells / ヒト臍帯静脈内皮細胞 / マトリックスメタロプロテアーゼ / 遺伝子組換え / α2-plasmin inhibitor / plasminogen receptor / Fibrin / マトリクスメタロプロテアーゼ(MMP) / 細胞性線溶 / cytokine / t-PAR / ウロキナーゼ受容体(u-PAR) / plasminogen複合体 / carcinoma cells / 組織性プラスミノーゲンアクチベータ(t-PA) / uーPA / 遺伝子欠損マウス / gene expression / 遺伝子発現調節 / PAl-1 / 血液線溶系 / plasminogen activator / PAIー1 / 細胞障害 / fibrinolysis / t-PAR系 / vascular endothelial cell / ウロキナーゼ(u-PA) / タンパク分解活性 / tーPA・PAIー1 / Pro-UK / 組織再生 / ラット創傷治癒モデル / 血液凝固 / t-PA receptor / ECM / 創傷治癒モデル / knockout mouse / Plasminogen activation / Fibrinolysis / proteolysis activity / CD / tーPA / Angiogenesis / PLGF / fibrinolytic system / 血管 / NMR / 腫瘍細胞 / 細胞移動 / Knock out mouse / タンパク分解 / Endothelial cells / プラスミノーゲン / tissue type plasminogen activator (t-PA) / フィブリン親和性 / 線溶系因子 / 血液レオロジー / 線溶 / Fibrinolytic system / staphylokinase / 蛋白分解 / Fibrinolytic activity / gene targeting mouse / バイオテクノロジー / biotechnology … More
Except Principal Investigator
血管内皮細胞 / プラスミノーゲン / 線溶系 / plasminogen / 抗血栓性 / t-PA / ペプチド / アントシアニン / poly(O-methacryloyl-L-serine) / 遺伝子欠損マウス / poly(2-hydroxypropylmethacrylamide) / 血管新生 / poly(N^ε-methacrylamide-L-lysine) / poly(N^α-methacrylamide-L-lysine) / t-PA受容体 / 動脈硬化 / 脂肪細胞 / poly(N-isopropylacrylamide) / 光刺激細胞剥離 / 天然資源物質 / 線溶因子 / 脳定量障害モデル / アディポネクチン / O-メタクリロイル-L-セリン / 生体分子間相互作用解析 / thermo-sensitive polymer / 低温プラズマ処理・ポスト重合 / プラスミノーゲン結合部位 / Plasminogen activator / 肥満 / ブロックコポリマー / fibrinolytic factor / bFGF / 細胞内シグナル伝達 / 病態生理 / プラスミノーゲンアクチベータ / thermo-stimuli cells detachment / エチルホスホリルコリン / 温度刺激細胞剥離 / アディポサイトカイン / チロシンリン酸化蛋白 / 蛋白分解カスケード / Protein adsorption / α_2-antiplasmin / 血漿タンパク質 / bone marrow / C3G / ミクロ相分離構造 / bEnd.3 / plasminogen binding / 抗血栓性材料 / Polydimethylsiloxane / マクロアゾ開始剤 / α_2-アンチプラスミン / u-PA / 脳浮腫 / マウス / t-PAR / シアニジン / uPAR / α_2ーアンチプラスミン / Vascular endothelial cells / light-stimuli cells detachment / Antithrornbotic property / poly(N-α-methacrylamide-L-lysine) / HeLa cells attachment and proliferation / 血管透過性 / plasma irradiation-post polymerization / 塩基性線維芽細胞増殖因子 / 脳損傷 / plasminogen activator / ポリエーテルウレタン / Brain edema / 肝再生 / Poly(O-methacryloyl-L-serine) / メタクリル酸メチル / poly(isopropylacrylamide) / ポリジメチルシロキサン / ヒドロゲル層 / 細胞培養用基材 / 細胞外基質 / staphylokinase / poly(N-2-hydroxypropylmethacrylamide) / 2-(ヒドロキシプロピル)メタクリルアミド / Mitogen-activated protein kinase (MAPK) / Thrombogenicity / プラスミノーゲンアクチベ / Tyrosine phosphorylation / プラズマ照射-ポスト重合 / 組織再生 / thrombin inhibition / スタヒロキナーゼ / 血液凝固 / Intracellular signal transduction / ECM / 光応答性ポリマー / 遊走 / 脳梗塞 / 創傷治癒 / 2-(メタクリロイルオキシ)エチルホスホリルコリン / Brain injury / 感温性ポリマー / Macroazo initiator / 細胞内伝達系 / プラスミノーゲンアクチベーター / gene deficient mice / Angiogenesis / 感熱性ポリマー / PAI-1 / tPA / ウロキナーゼ / 熱刺激細胞剥離 / 合成発色基質S2238 / 温度応答性ポリマー / ウロキナーゼレセプター / スタフィロキナーゼ / α2-アンチプラスミン / 血管平滑筋細胞 / 骨髄細胞移植 / 血栓溶解 / Polyether urethane / 神経外傷 / Resonant mirror biosensor / フローサイトメトリー / light-sensitive polymer / 酸素グルコース除去 / alpha2-antiplasmin / 線溶系因子 / 能浮腫 / 血液レオロジー / トロンビン活性阻害 / 蛋白分解活性 / HeLa細胞の接着・増殖 / t-PA receptor (t-PAR) / Phospholipid monomer / Fibrinolytic system / プラスミノゲン / tissue-type plasminogen activator (t-PA) / プラスミン活性促進 / チロシンリン酸化 / HeLa細胞 / ミクログリア / フィブリン線溶活性 / liver regeneration / Hydrogel layer / MAPK / uPA / 酸素グルコース除 / 遊走能 / 合成発色基質S2251 / Block copolymer / 線維芽細胞 Less
  • Research Projects

    (25results)
  • Research Products

    (14results)
  • Co-Researchers

    (15People)
  •  New synthetic peptide enhances regeneration of tissues

    • Principal Investigator
      OKADA Kiyotaka
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Study of natural resources improving the interaction between adipocytes and vascular endothelial cells

    • Principal Investigator
      UESHIMA Shigeru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Kinki University
  •  Analysis of vascular remodeling by t-PA/t-PAR systemPrincipal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Roles of urokinase plasminogen activator receptor expressed in endothelial cells on deterioration of ischemic stroke

    • Principal Investigator
      NAGAI Nobuo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
      Kinki University
  •  New synthetic peptide enhances plasminogen activation and thrombolysis

    • Principal Investigator
      OKADA Kiyotaka
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Studies of food ingredients which improve the physiological function of adipocyte through modulation of adipocytokine secretion

    • Principal Investigator
      UESHIMA Shigeru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Kinki University
  •  Analysis of regulation by t-PA/t-PAR-mediate protease on regeneration system after tissue damagePrincipal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Analysis of biological function by t-PA receptor gene expression regulationPrincipal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  The role of proteolytic system on the liver regeneration : The analysis of gene deficient mice with transplantation of bone morrow

    • Principal Investigator
      OKADA Kiyotaka
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Expression of t-PA receptor on the endothelial cell and analysis of its physiological function.Principal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Evaluation of anticoagulant behavior of thrombin-inhibiting polymer with fibrinolytic factor-binding sites and application for biomaterials

    • Principal Investigator
      SHIRAISHI Kohei
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kinki University
  •  Analysis of the mechanism of angiogenesis regulated by fibrinolytic factorsPrincipal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Development of stimuli-sensitive polymer hydrogel as a scaffold for tissue engineering

    • Principal Investigator
      SUGIYAMA Kazuo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kinki University
  •  Molecular cloning, intracellular siginal transduction and biological significance of PA receptor

    • Principal Investigator
      FUKAO Hideharu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Department of Physiology, Kinki University School of medicine
  •  Analysis of the biological function of vascular smooth muscle cells regulated by fibrinolytic factorsPrincipal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Department of Physiology, Kinki University School of Medicine
  •  ROLES OF PLASMINOGEN ACTIVATORS UPON BRAIN INJURY

    • Principal Investigator
      KATAOKA Kazuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KINKI UNIVERSITY
  •  Analysis of fibrinolytic activation mechanism by staphylokinase in gene deficient mice

    • Principal Investigator
      OKADA Kiyotaka
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Analysis of angiogenesis in fibrinolytic factordefficient micePrincipal Investigator

    • Principal Investigator
      MATSUO Osamu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Department of Physiology, Kinki University School of Medicine
  •  Preparation of dimethylsiloxane type of block copolymer * with nonthrombogenicity as biomedical materials

    • Principal Investigator
      SUGIYAMA Kazuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      KINKI UNIVERSITY
  •  血管内皮細胞におけるu-PA/u-PAR系による分化制御機構の解析Principal Investigator

    • Principal Investigator
      松尾 理
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  血管内皮細胞からのt-PA受容体(t-PAR)の精製と分子生物学的同定

    • Principal Investigator
      深尾 偉晴
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  血管内皮細胞における細胞性線溶の統御Principal Investigator

    • Principal Investigator
      松尾 理
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  血管内皮細胞上でのstaphylokinaseによる酵素活性発現の解析Principal Investigator

    • Principal Investigator
      松尾 理
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Extracellular matrixの酵素活性制御機序Principal Investigator

    • Principal Investigator
      松尾 理
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kinki University
  •  Pro-UKとt-PAのフィブリン親和性発現機序の差異Principal Investigator

    • Principal Investigator
      松尾 理
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kinki University

All 2011 2010 2009 2008

All Journal Article Book

  • [Book] Recent Advances in Thrombosis and Hemostasis.(Tanaka K, Davie EW (eds))(Role of fibrinolysis in hepatic regeneration.)2008

    • Author(s)
      Okada K, Ueshima S, Matsuo O.
    • Publisher
      Tokyo, Springer Japan
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] A synthetic peptide derived from staphylokinase enhances plasminogen activation by tissue-type plasminogen activator.2011

    • Author(s)
      岡田清孝, 上嶋繁, 松尾理, 他
    • Journal Title

      J Thromb Haemost (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] The absence of urokinase-type plasminogen activator receptor plays a role in the insulin-independent glucose metabolism.2011

    • Author(s)
      Tomogane K, Ueshima S, Okada K, Matsuo O, 他4
    • Journal Title

      J Cardiovasc Pharmacol 57(3)

      Pages : 334-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] Alpha2-antiplasmin is associated with the progression of fibrosis.2010

    • Author(s)
      Kanno Y, Ueshima S, Okada K, Matsuo O, 他
    • Journal Title

      Am J Pathol 176(1)

      Pages : 238-245

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] Enhancement of fibrinolytic activity in vascular endothelial cells by heterologous expression of adenine nucleotide translocase-1.2010

    • Author(s)
      Ishida C, Ueshima S, Okada K, Matsuo O, 他
    • Journal Title

      Blood Coagul Fibrinolysis 21(3)

      Pages : 272-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] 線溶系因子関連2010

    • Author(s)
      上嶋繁、松尾理
    • Journal Title

      Vasular Lab 7

      Pages : 17-21

    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] Urokinase-type plasminogen activator receptor is associated with the development of adipose tissue.2010

    • Author(s)
      Kanno Y, Ueshima S, Okada K, Matsuo O, 他
    • Journal Title

      Thromb Haemost 104(6)

      Pages : 1124-1132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] 血栓溶解療法のモニター2009

    • Author(s)
      上嶋繁、松尾理
    • Journal Title

      臨床検査 53

      Pages : 1181-1185

    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] 線溶系:血管外での新しい機能2008

    • Author(s)
      上嶋繁、岡田清孝、松尾理、他
    • Journal Title

      近畿大学医学雑誌 33

      Pages : 161-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] 深部静脈血栓症の病態2008

    • Author(s)
      上嶋繁、松尾理
    • Journal Title

      日本病態生理学会雑誌 17

      Pages : 37-39

    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] Binding of plasminogen to hepatocytes isolated from injured mouse liver and nonparenchymal-cell-dependent proliferation of hepatocytes.2008

    • Author(s)
      岡田清孝, 上嶋繁, 松尾理, 他
    • Journal Title

      Blood Coagul Fibrinolysis 19(6)

      Pages : 503-511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] 深部静脈血栓症の病態2008

    • Author(s)
      上嶋繁、松尾理
    • Journal Title

      日本血栓止血学会誌 19

      Pages : 485-490

    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] Alpha2-antiplasmin is a critical regulator of angiotensin II-mediated vascular remodeling.2008

    • Author(s)
      Hou Y, Okada K, Okamoto C, Ueshima S, Matsuo O
    • Journal Title

      Arterioscler Thromb Vasc Biol 28(7)

      Pages : 1257-1262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • [Journal Article] The absence of uPAR attenuates insulin-induced vascular smooth muscle cell migration and proliferation.2008

    • Author(s)
      Kanno Y, Okada K, Ueshima S, Matsuo O, 他
    • Journal Title

      Thromb Res 123(2)

      Pages : 336-341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590241
  • 1.  OKADA Kiyotaka (20185432)
    # of Collaborated Projects : 22results
    # of Collaborated Products : 10results
  • 2.  UESHIMA Shigeru (30193791)
    # of Collaborated Projects : 17results
    # of Collaborated Products : 14results
  • 3.  FUKAO Hideharu (70218874)
    # of Collaborated Projects : 10results
    # of Collaborated Products : 0results
  • 4.  KAWAO Naoyuki (70388510)
    # of Collaborated Projects : 8results
    # of Collaborated Products : 0results
  • 5.  NAGAI Nobuo (90260281)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 6.  SUGIYAMA Kazuo (00088577)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 7.  SHIRAISHI Kohei (10196602)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 8.  YAMASHITA Rina (90510876)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 9.  OKAMOTO Chikako (90368291)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 10.  高石 知明 (90268409)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 11.  KATAOKA Kazuo (10221178)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 12.  TANEDA Mamoru (10236713)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 13.  ASAI Toshiharu (20248008)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 14.  板東 博志 (20173122)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 15.  酒井 鉄博 (40113154)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results

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