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ONO Tsuneko  小野 恒子

ORCIDConnect your ORCID iD *help
Researcher Number 40035514
Other IDs
Affiliation (based on the past Project Information) *help 2012: 徳島大学, ヘルスバイオサイエンス研究部, 教授
2012: 徳島大学, 大学院・ヘルスバイオサイエンス 研究部, 教授
2008 – 2011: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授
2005 – 2007: 徳島大学, 医学部, 教授
2001: The University of Tokushima, Medicin, Professor, 医学部, 教授 … More
2001: School of Medicine, The University of Tokushima, Professor, 歯学部, 教授
1997 – 2000: 徳島大学, 歯学部, 助教授
1991 – 1996: 徳島大学, 歯学部, 講師
1986 – 1989: 徳島大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Morphological basic dentistry / Laboratory medicine
Except Principal Investigator
細菌学 / 病態科学系歯学(含放射線系歯学) / 小児・社会系歯学 / Morphological basic dentistry / Basic veterinary science/Basic zootechnical science / Morphological basic dentistry / 矯正・小児・社会系歯学 / 基礎獣医学 / Applied veterinary science
Keywords
Principal Investigator
rpoS / 付着 / rpoN / 抗菌薬抵抗性 / 緑膿菌 / erm gene / oral streptococci / vqsR / pvdS / tcp gene … More / Pseudomonas aeruginosa / ストレス応答 / ketolide / mefE gene / macrolide resistance / Streptococcus oralis / Streptococcus mitis / bacteremia / S.mutans / spaP / quorum sensing / PCR / ppGppc / adherent bacteria / stress response / antibiotic tolerance / 抗菌薬 / tolerance / pyoverdine / 遺伝子発現 / ppGpp / 付着細菌 / rpoS gene / bta gene / antibiotics tolerance / adherence / 熱ショック / P.pneumoniae / P. aeruginosa / bta遺伝子 / tcp遺伝子 / 薬剤排出ポンプ / トランスポゾン / マクロライド耐性 / PCR diagnosis / 敗血症 / spaP gene / Streptococcus.mutans / PCR診断 / wspF / RSCV / psl / cbrA / pslオペロン / バイオフィルム / カルバペネム / c-di-GMP / PQS / バイオフィルム感染症 / msr gene / macrolides resistance … More
Except Principal Investigator
CD15s / レンサ球菌 / EIA / S. intermedius / S.mutans / Monoclonal antibody / 単クロン抗体 / St.porcinus / neuraminidase / 遺伝子発現 / histone-like protein / CD8 / S.intermedius / liver / translocation / 心疾患 / S.pyogenes / Surface antigen / Group E streptococci / 表層抗原 / HPLC / E群連鎖球菌 / バイオフィルム / positive-selection vector / electroporation / mobilization / DNA sequence / gene cloning / pathogenicity / Bacteroides / shultle vector / DNase / トリプシン様プロテアーゼ / Bacteroides fragilis / Bacteroides gingivalis / 組換え体選択ベクター / エレクトロポレーション / neruaminidase / 遺伝子クローニング / バクテロイデス / 偏性嫌気性菌 / 正の選択ベクタ- / エレクトロポレ-ション / 易動化 / DNA塩基配列 / ノイラミニダ-ゼ / 遺伝子クロ-ニング / 病原性 / バクテロイデス属 / rifampicin / RNA polymerase / gene expression / RNA degradation / membrane permeability / transmissible plasmid / 転写 / リファンピシン / RNAポリメラーゼ / RNA分解 / 膜透過性 / 伝達性プラスミド / heparin / 腎疾患 / 分子モデル / 三次元構造 / ヒストン様蛋白 / ヘパリン / Enteric bacteria / Herbivores / Tannin-Protein comprex degrading bacteria / 腸内細菌 / 草食動物 / タンナーゼ産生菌 / abscesse / streptococcus / Lewisy / 脾臓 / 肝疾患 / autoimmunity / fosfomycin / streptococci / 肝 / 自己免疫反応 / ホスホマイシン / sialy Lewis^X / Kawasaki syndrome / oral streptococci / heart disease / sialyl Lewis^X / sialyl Lewis^x / 川崎病 / epitope / N-acethylglucosamine / monoclonal antibody / 齲蝕活動性 / 迅速簡便同定法 / N-アセチルグルコサミン / 齲蝕活動性試験 / モノクロン抗体 / 酵素免疫測定法 / ミュータンスレンサ球菌 / Genotype / Hybridization / GC content / Str.porcinus / 相同性 / GC含量 / 遺伝子型 / Mutans group of streptococci / Caries risk / membrane filtre-EIA / Enzyme immunoassay / Streptococcus.mutans / Diagnostic kit / 遺伝子型別 / ハイブリドーマ / 血清型 / 迅速診断法 / 酵素標識抗体 / DMF / プロトタイプ / う蝕 / ミュータンス群連鎖球菌 / 酵素標識抗体法 / メンブレンフィルター・EIA / う蝕発生リスク / 診断キット / Mannose(Mannosamine) / Antigenic determinant / Anti-phagocytic factor / 多糖抗原 / 抗補食因子 / 蛋白抗原 / 特異性 / 補体 / 貧食 / 捕食実験 / マンノース(アミン) / 抗原決定基 / 抗捕食因子 / 抗菌薬抵抗性 / 緑膿菌 / 歯学 / 細菌 / 抗生物質 / 感染症 / 遺伝子 / 口腔細菌学 Less
  • Research Projects

    (19 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (20 People)
  •  The screening for antibiotic tolerance related genes in peg-biofilm cells of Pseudomonas aeruginosa

    • Principal Investigator
      MIYAKE Yoichiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  Regulatory Network for Expression of Antibiotic Tolerance in Pseudomonas aeruginosaPrincipal Investigator

    • Principal Investigator
      ONO Tsuneko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      The University of Tokushima
  •  The relationship between biofiim formation and antibiotio toIerance in Pseudomonas aeruginosa

    • Principal Investigator
      三宅 洋一郎
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  Molecular analysis of anteliotic-tolerance and stress response in adherent bacteriaPrincipal Investigator

    • Principal Investigator
      ONO Tsuneko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  The Mechanism of Antibiotic-tolerance in Adherent bacteriaPrincipal Investigator

    • Principal Investigator
      ONO Tsuneko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  A study Of ora| streptococcal histone-like protein and virulence mechanism

    • Principal Investigator
      HIROTA Katsuhiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      The University of Tokushima
  •  A stady of tannin-protein comprex degrading enteric bacteria isolated from herbivores.

    • Principal Investigator
      NEMOTO Ken
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Tokushima University
  •  The Mechanism of Antibiotic-Resistance in Oral StreptococciPrincipal Investigator

    • Principal Investigator
      ONO Tsuneko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  Examine pathogenicity of oral Streptococcus spp. by its surface antigens on liver disease

    • Principal Investigator
      HIROTA Katuhiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      The University of Tokushima
  •  A study of oral streptococci on the dherence and resistance to human immune system and antibacterial agents

    • Principal Investigator
      MIYAKE Yoichiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  口腔連鎖球菌の病原性および薬剤耐性機構の解明Principal Investigator

    • Principal Investigator
      小野 恒子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  Diagnosis of streptococcal infection by PCR amplificationPrincipal Investigator

    • Principal Investigator
      ONO Tsuneko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      The University of Tokushima
  •  Immunological analysis of a cell surface antigen by a monoclonal antibody SNH-3 in oral streptococci

    • Principal Investigator
      HIROTA Katsuhiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      The University of Tokushima
  •  DEVELOPMENT OF A DIAGNISTIC KIT FOR RAPID EVALUATION OF CARIES ACTIVITY

    • Principal Investigator
      OTA Fusao
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      小児・社会系歯学
    • Research Institution
      THE UNIVERSITY OF TOKUSHIMA
  •  STUDY ON THE SURFACE ANTIGENS AND GENOTYPES OF GROUP E STREPTOCOCCI

    • Principal Investigator
      YAMATO Masayuki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      基礎獣医学
    • Research Institution
      THE UNIVERSITY OF TOKUSHIMA
  •  Simple and Rapid Identification of the Mutans Group of Streptococci by Enzyme Immunoassay using Monoclonal Antibodies

    • Principal Investigator
      HIROTA Katsuhiko
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      小児・社会系歯学
    • Research Institution
      The University of Tokushima
  •  ANALYSIS AND PURIFICATION OF AN ANTI-PHAGOCYTIC FACTOR(S) OF CROUP ESTREPTOCOCCI PATHOGENIC FOR LYMPHADENITIS IN PIGS

    • Principal Investigator
      OTA Fusao
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      THE UNIVERSITY OF TOKUSHIMA
  •  Molecular genetic studies on pathogenicity of genus Bacteroides.

    • Principal Investigator
      OHNISHI Yoshinari
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokushima
  •  Transmissible plasmid genes increase membrane permeability: function and regulatory mechamism of gene expression.

    • Principal Investigator
      AKIMOTO Shigeru
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokushima

All 2012 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] Pseudomonas aeruginosaのバイオフィルム形成と抗菌薬抵抗性に関する遺伝子ネットワーク2012

    • Author(s)
      小野恒子, 村上圭史, 三宅洋一郎
    • Journal Title

      日本細菌学雑誌

      Volume: 67巻 Pages: 227-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590627
  • [Journal Article] The role of rpoS geneand quorum-sensing system in ofloxacin tolerance in Pseudomonas aeruginosa2009

    • Author(s)
      Kayama S., Murakami K., Ono T., Ushimaru M., Yamamoto A., Hirota K., Miyake Y.
    • Journal Title

      FEMS Microbiol. Lett

      Volume: 298 Issue: 2 Pages: 184-192

    • DOI

      10.1111/j.1574-6968.2009.01717.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590627
  • [Presentation] 緑膿菌臨床分離株の付着菌表現型におけるcycHc-di-GMPの関与について2009

    • Author(s)
      谷口友伯、鹿山鎭男、山本明毅、小野恒子、弘田克彦、三宅洋一郎、長宗秀明
    • Organizer
      第82回日本細菌学会総会平成
    • Place of Presentation
      名古屋
    • Year and Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-19592115
  • [Presentation] 緑膿菌臨床分離株の付着時性状におけるcychc-di-GMPの関与について2008

    • Author(s)
      谷口友伯、鹿山鎭男、小野恒子、山本明毅、弘田克彦、三宅洋一郎
    • Organizer
      第56回日本化学療法学会西日本支部総会
    • Place of Presentation
      広島
    • Year and Date
      2008-12-06
    • Data Source
      KAKENHI-PROJECT-19592115
  • [Presentation] 付着状態における緑膿菌の抗菌薬抵抗性と遺伝子発現についてBacterialAdherence&Biofilm2008

    • Author(s)
      鹿山鎭男、弘田克彦、小野恒子、三宅洋一郎
    • Organizer
      第22回学術集会
    • Place of Presentation
      淡路
    • Year and Date
      2008-07-04
    • Data Source
      KAKENHI-PROJECT-19592115
  • [Presentation] 付着状態における緑膿菌の抗菌薬抵抗性と遺伝子発現について2008

    • Author(s)
      鹿山鎭男、弘田克彦、小野恒子、三宅洋一郎
    • Organizer
      第81回日本細菌学会総会第81回日本細菌学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19592115
  • [Presentation] 緑膿菌Quorumsensin機構とbiapenem抵抗性について2007

    • Author(s)
      鹿山鎭男、小野恒子、弘田克彦、劉大力、HelliSusilowati、三宅洋一郎
    • Organizer
      第60回日本細菌学会中国・四国支部総会
    • Place of Presentation
      岡山
    • Year and Date
      2007-10-14
    • Data Source
      KAKENHI-PROJECT-19592115
  • 1.  HIROTA Katsuhiko (60199130)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 5 results
  • 2.  MIYAKE Yoichiro (80136093)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 7 results
  • 3.  NEMOTO Ken (10218274)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 4.  OTA Fusao (90035478)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  FUKUI Komei (40035407)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  MURAKAMI Keiji (10335804)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 7.  KAYAM Ashizuo (50432761)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 8.  TAMATO Masayuki (90210492)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KUWAHARA Tomomi (60263810)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TAKEOKA Aya (00116831)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  AKIMOTO Shigeru (10159337)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  OHNISHI Yoshinari (10037400)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  TETSUYA Yoshinaga (40220694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MINATO Yoshihiro (00035768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NISHINO Mizuho (90029976)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ABIKO Yoshimitsu (70050086)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HIGUCHI Tomihiko (50035557)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KINOUCHI Takemi (80136217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  安富 豊 (50240891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  宮崎 寿次
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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