YOSHINO Makoto 芳野信

… Alternative Names

芳野信ヨシノマコト

Less

Researcher Number	40080569
Other IDs
External Links
Affiliation (Current)	2025: 久留米大学, 付置研究所, 客員教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 久留米大学, 付置研究所, 客員教授 1996 – 2007: 久留米大学, 医学部, 教授 1994 – 1995: 久留米大学, 医学部, 助教授 1991: Kurume University School of Medicine, Associate Professor, 医学部, 助教授 1990: 久留米大学, 医学部・小児科, 助教授
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Pediatrics / Pediatrics / 内分泌・代謝学
Keywords	Principal Investigator オルニチントランスカルバミラーゼ / screening / 発症予防 / スクリーニング / オルニチントランスカルバミラーゼ欠損症 / 高アンモニア血症 / Mutation / 変異 / 体タンパク質 / ｍTOC1 … More / オルニチン / アルギニン / グルタミノリシス / グルタミン酸 / ジメチルa-ケトグルタル酸 / 尿素サイクル / アンモニア / α-ケトグルタル酸Na / 治療 / タンパク質合成 / mTORC1 / α-ケトグルタル酸 / male patients / late-onset presentation / ornithine transcarbamylase deficiency / オルチニントランスカルバミラーゼ欠損症 / 予後因子 / 遺伝疫学 / 遅発男子例 / prevention / orinithine transcarbamylase / オルニチントランスカルパミラーゼ / 一塩基置換 / localization / mitochondria / ornithine transcarbamylase / 転送 / 局在化 / ミトコンドリア / カルバミラーゼ / Ornithine transcarbamylase gene / Male / Late onset / Hyperammonemia / Ornithine transcarbamylase / 分子機構 / 遅発 / 発現 / 変異遺伝子 / オルニチントランスカルバミラーゼ遺伝子 / 男子 / 遅発型 / Japanese population / Phenylalanine hydroxylase / Phenylketonuria / 遺伝子 / フェニ-ルアラニン代謝異常 / 日本人 / 遺伝子変異 / フェニ-ルアラニン水酸化酵素 / フェニ-ルケトン尿症 … More Except Principal Investigator MALDI-TOF-MS / Wilson disease / hypoceruloplasminemia / proteome analysis / Cerulonlasmin / 質量分析 / ウィルソン病 / 低セルロプラスミン血症 / ペプチド解析 / セルロプラスミン / Gene transduction / Gutted adenovirus / Chimeric virus / Liver / Retrovirus / Adenovirus / Congenital metabolic diseases / Gene therapy / ガットレス / 遺伝子導入 / 血友病 / 遺伝子導入法 / ガットレスアデノウイルス / キメラウイルス / 肝 / レトロウイルス / アデノウイルス / 先天代謝疾患 / 遺伝子治療 / expression analysis / late onset / ornithine transcarbamylase deficiency / 発現実験 / 遅発型 / オルニチントランスカルバミラーゼ欠損症 Less

Novel therapeutic strategy for hyperammonemia based on nitrogen repositioning by the use of low molecular biological compoundsPrincipal Investigator
- Principal Investigator
  
  芳野信
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Structural Analysis of Serum Ceruloplasmin Peptides From The Patients With Wilson disease and Familial Hypoccerulosminemia
- Principal Investigator
  
  WATANABE Yoriko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
A study on Presymptomatic recognition and prevention of late-onset ornithine transcarbamylase deficiency in malePrincipal Investigator
- Principal Investigator
  
  YOSHINO Makoto
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
A Study on Molecular Epidemiology and Prevention of Onset of Late-onset Ornithine Transcarbamylase Deficiency in Male PatientsPrincipal Investigator
- Principal Investigator
  
  YOSHINO Makoto
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KURUME UNIVERSITY
A development of novel vectors and an establishment of a new generation of hepatic gene therapy for congenital metabolic diseases
- Principal Investigator
  
  KOSAI Ken-ichiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Gifu University
Molecular Mechanism of Localization of the Mutant Ornithine Transcarbamylase to Mitochondrial CompartmentPrincipal Investigator
- Principal Investigator
  
  YOSHINO Makoto
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KURUME UNIVERSITY
Molecular basis of late onset ornithine transcarbamylase deficiency in male
- Principal Investigator
  
  NISHIYORI Atsushi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kurume University
Molecular Mechanism of Late Onset Type of Ornithine Transcarbamylase Deficiency in MalesPrincipal Investigator
- Principal Investigator
  
  YOSHINO Makoto
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University School of Medicine
A study on the mutations at the phynylalanine hydroxylase gene among the Japanese populationPrincipal Investigator
- Principal Investigator
  
  YOSHINO Makoto
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Department of Pediatrics & Child Health, Kurume University School of Medicine

All 2023 2022 2021 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] ライソゾーム病‐最新の病態、診断、治療の進歩‐（改定第2版）2023
- Author(s)
  芳野　信
- Total Pages
  307
- Publisher
  診断と治療社
- ISBN
  9784787825971
- Data Source
  KAKENHI-PROJECT-21K07811
[Book] 高アンモニア血症　小児科診療ガイドライン―最新の診療指針―（第５版）2022
- Author(s)
  福井香織、渡邊順子、芳野　信
- Total Pages
  848
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-21K07811
[Book] 今日の治療と看護改訂 : 第2版2004
- Author(s)
  芳野信
- Total Pages
  1586
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Book] 小児科外来診療のコツと落とし穴5小児救急2004
- Author(s)
  芳野信
- Total Pages
  249
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Book] 今日の治療と看護改定第2版2004
- Author(s)
  芳野信
- Total Pages
  1586
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15591148
[Book] 今日の小児治療指針第13版(尿素サイクル異常症)2003
- Author(s)
  芳野信
- Total Pages
  690
- Publisher
  医学書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Moving towards a novel therapeutic strategy for hyperammonemia that targets glutamine metabolism2022
- Author(s)
  Fukui K, Takahashi T, Matsunari H, Uchikura A, Watanabe M, Nagashima H, Ishihara N, Kakuma T, Watanabe Y, Yamashita Y, Yoshino M
- Journal Title
  
  J Inherit Metab Dis
  
  Volume: 46(6) Issue: 6 Pages: 1059-1069
- DOI
  10.1002/jimd.12540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08198, KAKENHI-PROJECT-21K07811
[Journal Article] Novel ARG1 variants identified in an arginase 1 deficient patient Human Genome Variation2021
- Author(s)
  Yokoi K, NakajimaY, Shinkai Y, Yasui T, Yoshino M, Yoshikawa T, Ito T, Hiroki Kurahashi H
- Journal Title
  
  Human Genome Variation
  
  Volume: 8 Issue: 1 Pages: 2-4
- DOI
  10.1038/s41439-021-00139-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07811
[Journal Article] Paternal transmission and slow elimination of mutant alleles associated with late-onset ornithine transcarbamylase deficiency in male patients2008
- Author(s)
  Numata S, Harada E, Maeno Y, Ueki I, Watanabe Y, Fujii C, Yanagawa T, Takenaka S, Inoue T, Inoue S, Goushi T, Yasutake T, Mizuta T, Yoshino M
- Journal Title
  
  J Hum Genet 53
  
  Pages: 10-17
- NAID
  10021247384
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Paternal transmission and slow elimination of mutant alleles associated with late-onset ornithine transcarbamylase deficiency in male patients.2008
- Author(s)
  Numata S, Harada E, Maeno Y, Ueki I, Watanabe Y, Fujii C, Yanagawa T, Takenaka S, Inoue T, Inoue S, Goushi T, Yasutake T, Mizuta T, Yoshino M.
- Journal Title
  
  J Hum Genet 53(doi ; 10.1007/s10038-007-0212-8)
  
  Pages: 10-17
- NAID
  10021247384
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Roles of some cytokines in bone remodeling and hematopoiesis in Gaucher disease.2007
- Author(s)
  Yoshino M, Watanabe Y, Thkunaga Y, Harada E, Fujii C, Numata S, Harada M, Tajima A, Ida H.
- Journal Title
  
  Pediatr Int 49(doi : 10.1111/j.1442-200x.2007.02502.x)
  
  Pages: 959-956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Novel mutations in five Japanese patients with 3-methylcrotonyl-CoA carboxylase deficiency2007
- Author(s)
  Uematsu M, Sakamoto O, Sugawara N, Kumagai N, Morimoto T, Yamaguchi S, Hasegawa Y, Kobayashi H, Ihara K, Yoshino M, Watanabe Y, Inokuchi T, Yokoyama T, Kiwaki K, Nakamura K, Endo F, Tsuchiya S, Ohura T
- Journal Title
  
  J Hum Genet 52
  
  Pages: 1040-1043
- NAID
  10020022418
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Novel mutations in five Japanese patients with 3-methylcrotonyl-CoAcarboxylase deficiency2007
- Author(s)
  Uematsu M, Sakamoto O, Sugawara N, Kumagai N, Morimoto T, Yamaguchi S, Hasegawa Y, Kobayashi H, Ihara K, Yoshino M, Watanabe Y, Inokuchi T, Yokoyama T, Kiwaki K, Nakamura K, Endo F, Tsuchja S, Ohura T
- Journal Title
  
  J Hum Genet 52
  
  Pages: 1040-1043
- NAID
  10020022418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Roles of specific cytokines in bone remodeling and hematopoiesis in Gaucher disease2007
- Author(s)
  Yoshino M, Watanabe Y, Tokunaga Y, Harada E, Fujii C, Numata S, Harada M, Tajima A, Ida H
- Journal Title
  
  Pediatr Int 49
  
  Pages: 959-965
- NAID
  10024152088
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Novel mutations in five Japanese patients with 3-methylcrotonyl-C0A carboxylase deficiency.2007
- Author(s)
  Uematsu M, Sakamoto O, Sugawara N, Kumagai N, Morimoto T,Yamaguchi S, Hasegawa Y, Kobayashi H, Ihara K, Yoshino M,Watanabe Y, Inokuchi T, Yokoyama T. Kiwaki K, Nakamura K, Endo F, Tsuchiya S, Ohura T.
- Journal Title
  
  J Hum Genet. 52(doi : 10.1007/s10038-007-0211-9)
  
  Pages: 1040-1043
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] 栄養療法で急性期治療を行ったメープルシロップ尿症の1例2006
- Author(s)
  岡田純一郎, 渡辺順子, 平井裕子, 神戸太郎, 廣瀬彰子, 藤野浩, 前野泰樹, 芳野信
- Journal Title
  
  日本マススクリーニング学会雑誌 16
  
  Pages: 63-67
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Late-onset ornithine transcarbamylase deficiency in male patients : Prognostic factors and characteristics of plasma amino acid profile.2006
- Author(s)
  Harada E, Nishiyori A, Tokunaga Y, Watanabe Y, Kuriya N, Kumashiro R, Kuno T, Kuromaru R, Hirose S, Ichikawa K, Yoshino M.
- Journal Title
  
  Pediatr Int 48
  
  Pages: 105-111
- NAID
  10018195131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Late-onset ornithine transcarbamylase deficiency in male patients:Prognostic factors and characteristics of plasma amino acid profile2006
- Author(s)
  Harada E, Nishiyori A, Tokunaga Y, Watanabe Y, Kuriya N, Kumashiro R, Kuno T, Kuromaru R, Hirose S, Ichikawa K, Yoshino M
- Journal Title
  
  Pediatr Int 48
  
  Pages: 105-111
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Late-onset Ornithine Transcarbamylase Deficiency in Male Patients : Prognostic Factors and Characteristics of Plasma Amino Acid Profile2006
- Author(s)
  Harada E, Nishiyori A, Tokunaga Y, Watanabe Y, Kuriya N, Kumashiro R, Kuno T, Kuromaru R, Hirose S, Ichikawa K, Yoshino M
- Journal Title
  
  Pediatrics International 48
  
  Pages: 105-111
- NAID
  10018195131
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Late-onset ornithine transcarbamylase deficiency inmale patients:Prognostic factors and characteristics of plasma amino acid profile.2006
- Author(s)
  Harada E, Nishiyori A, Tokunaga Y, Watanabe Y, Kuriya N,Kumasbiro R, Kuno T, Kuromaru R, Hirose 5, Ichikawa K,Yoshino M.
- Journal Title
  
  Pediatr Int 48(doi : 10.1111/j.1442-200x.02181.x)
  
  Pages: 105-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Late-onset ornithine transcarbamylase deficiency in male patients : Prognostic factors and characteristics of plasma amino acid profile.2006
- Author(s)
  Harada E, Nishiyori A, Tokunaga Y, Watanabe Y, Kuriya N, Kumashiro R, Kuno T, Kuromaru R, Hirose S, Ichikawa K, Yoshino M
- Journal Title
  
  Pediatr Int 48
  
  Pages: 105-111
- NAID
  10018195131
- Data Source
  KAKENHI-PROJECT-17591125
[Journal Article] Late-onset ornithine transcarbamylase deficiency in male patients : Prognostic factors and characteristics of plasma amino acid profile.2006
- Author(s)
  Harada E, Nishiyori A, Tokunaga Y, Watanabe Y, Kuriya N, Kumashiro R, Kuno T, Kuromaru R, Hirose S, Ichikawa K, Yoshino M
- Journal Title
  
  Pediatr Int 48
  
  Pages: 105-111
- NAID
  10018195131
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Ornithine transcarbamylase deficiency : recurrence of mutations associated with late-onset disease in maple patients in unrelated families and phenotypic variability2005
- Author(s)
  Watanabe Y, Harada E, Yoshino M
- Journal Title
  
  Journal of Inherited Metabolic Disease 28・suppl.
  
  Pages: 67-67
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] 小児の検査とインフォームドコンセント2005
- Author(s)
  芳野信
- Journal Title
  
  小児看護 28・4
  
  Pages: 461-465
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Ornithine transcarbamylase deficiency : recurrence of mutations associated with late-onset disease in maple patients in unrelated families and phenotypic variability2005
- Author(s)
  Watanabe Y, Harada H, Yoshino M
- Journal Title
  
  J Inherit Metab Dis 28 - suppl.
  
  Pages: 67-67
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Omithine transcarbamylase deficiency : recurrence of mutations associated with late-onset disease in maple patients in unrelated families and phenotypic variability.2005
- Author(s)
  Watanabe Y, Harada H, Yoshino M.
- Journal Title
  
  J Inherit Metab Dis 28 suppl
  
  Pages: 67-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Informed consent on laboratory studies in children.2005
- Author(s)
  Yoshino M.
- Journal Title
  
  Pediatr Nursing 28
  
  Pages: 461-465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Pyruvate dehydrogenase E1 α subunit deficiency in a female patient : evidence of antenatal origin of brain damage and possible etiology of infantile spasms.2004
- Author(s)
  Wada N, Matsuishi T, Nonaka M, Naito E, Yoshino M.
- Journal Title
  
  Brain & Dev 26
  
  Pages: 57-60
- NAID
  10013565930
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Long-term treatment and diagnosis of tetrahydrobiopterin-responsive hyperphenylalaninemia with a mutant phenylalanine hydroxylase gene.2004
- Author(s)
  Shintaku H, Kure S, Ohura T, Okano Y, Ohwada M, Sugiyama N, Sakura N, Yoshida I, Yoshino M, Matsubara Y, Suzuki K, Aoki K, Kitagawa T.
- Journal Title
  
  Pediatr Res 55
  
  Pages: 425-430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Inborn errors of metabolism in pediatric emergency medicine.2004
- Author(s)
  Yoshino M.
- Journal Title
  
  Pitfalls and knack in Pediatric Practice, No.5 Pediatric Emergency Care, section 94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Pyruvate dehydrogenase El a subunit deficiency in a female patient : evidence of antenatal origin of brain damage and possible etiology of infantile spasms.2004
- Author(s)
  Wada N, Matsuishi T, Nonaka M, Naito E, Yoshino M
- Journal Title
  
  Brain & Dev. 26
  
  Pages: 57-60
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Long-term treatment and diagnosis of tetrahydrobiopterin - responsive hyperphenylalaninemia with a mutant phenylalanine hydroxylase gene.2004
- Author(s)
  Shintaku H, Kure S, Ohura T, Okano Y, Ohwada M, Sugiyama N, Sakura N, Yoshida I, Yoshino M, Matsubara Y, Suzuki K, Aoki K, Kitagawa T
- Journal Title
  
  Pediatr Res 55
  
  Pages: 425-430
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Investigation on the IVS5 +5G → A splice site mutation of HPS1 gene found in Japanese patients with Hermansky-Pudlak syndrome.2004
- Author(s)
  Suzuki T, Ito S, Inagaki K, Suzuki N, Tomita Y, Yoshino M, Hashimoto T
- Journal Title
  
  J Dermatol Sci 36
  
  Pages: 106-108
- NAID
  10016185356
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Investigation on the IVS5+5G→A splice site mutation of HPS1 gene found in Japanese patients with Hermansky-Pudlak syndrome.2004
- Author(s)
  Suzuki T, Ito S, Inagaki K, Suzuki N, Tomita Y, Yoshino M, Hashimoto T.
- Journal Title
  
  J Dermatol Sci 36
  
  Pages: 106-108
- NAID
  10016185356
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Identification of 16 novel mutations in the argininosuccinate synthetase gene and genotype-phenotype correlation in 38 classical citrullinemia patients.2003
- Author(s)
  Gao H-Z, Kobayashi K, Yoshino M, Nakagawa S, Saheki T
- Journal Title
  
  Hum Mutat 22
  
  Pages: 23-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Identification of 16 novel mutations in the argininosuccinate synthetase gene and genotype-phenotype correlation in 38 classical citrullinemia patients.2003
- Author(s)
  Gao H-Z, Kobayashi K…, Yoshino M…, Nakagawa S, Saheki T.
- Journal Title
  
  Hum Mutat 22
  
  Pages: 24-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Effect of supplementation with L-carnitine at a small dose on acycarnitine profiles in serum and urine andthe renal handling of acylcarnitines in a patient withmultiple acylcoenzyme A dehydrogenation defect.2003
- Author(s)
  Yoshino M, Tokunaga Y, Watanabe Y, Yoshida I, Sakaguchi M, Hata I, Shigematsu Y, Kimura M, Yamaguchi S.
- Journal Title
  
  J Chromatogr B 792
  
  Pages: 73-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Urea cycle disorders.2003
- Author(s)
  Yoshino M.
- Journal Title
  
  Today's Therapy in Pediatrics, 13^<th>ed.
  
  Pages: 690-690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Journal Article] Effect of supplementation with L-carnitine at a small dose on acylcarnitine profiles in serum and urine and the renal handling of acylcarnitines in a patient with multiple acyl-coenzyme A dehydrogenation defect.2003
- Author(s)
  Yoshino M, Tokunaga Y, Watanabe Y, Yoshida I, Sakaguchi M, Hata I, Shigematsu Y, Kimura M, Yamaguchi S
- Journal Title
  
  J Chromatogr B 792
  
  Pages: 73-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591148
[Presentation] Moving towards a novel therapeutic strategy for hyperammonemia that targets glutamine metabolism2023
- Author(s)
  Fukui K, Takahashi T, Matsunari H, Uchikura A, Watanabe M, Nagashima H, Kakuma T, Watanabe Y, Yamashita Y, Yoshino M
- Organizer
  6th Asian Congress on Inherited Metabolic Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07811
[Presentation] A novel therapeutic strategy for hyperammonemia that targets glutaminolysis2022
- Author(s)
  Fukui K, Takahashi T, Matsunari H, Uchikura A, Watanabe M, Nagashima H,3 Ishihara N, Kakuma T, Watanabe Y, Yamashita Y, Yoshino M
- Organizer
  The 125 Annual Meeting of the Japan Pediatric Society
- Data Source
  KAKENHI-PROJECT-21K07811
[Presentation] グルタミノリシスを標的とする高アンモニア血症の新規治療戦略2022
- Author(s)
  福井香織、高橋知之、松成ひとみ、内倉鮎子、渡邊将人、長嶋比呂志、石原直忠、角間辰之、渡邊順子、山下裕史朗、芳野　信
- Organizer
  第125回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07811
[Presentation] ジメチルα-ケトグルタル酸はグルタミン酸デヒドロゲナーゼのフラックス抑制によりアンモニアを低下させる2021
- Author(s)
  福井香織、高橋知之、渡邊順子、芳野　信
- Organizer
  第62回日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-21K07811
[Presentation] A novel therapeutic strategy for hyperammonemia that targets glutaminolysis2021
- Author(s)
  Fukui K, Takahashi T, Matsunari H, Uchikura A, Watanabe M, Nagashima H, Ishihara N, Kakuma T, Watanabe Y, Yamashita Y, Yoshino M.
- Organizer
  5th International Symposium on Urea Cycle Disorders
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07811

1. NISHIYORI Atsushi (30218226)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. WATANABE Yoriko (40258489)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. HARADA Eimei (90309790)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
4. TOKUNAGA Yasuyuki (60227585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKAO Mitsuyoshi (00217663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOSAI Ken-ichiro (90258418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高橋知之 (20332687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 瀬戸口修一 (80826032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高田二郎 (90122704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高橋和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

YOSHINO Makoto 芳野 信

芳野 信 ヨシノ マコト

Research Projects

Research Products

Co-Researchers

Novel therapeutic strategy for hyperammonemia based on nitrogen repositioning by the use of low molecular biological compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural Analysis of Serum Ceruloplasmin Peptides From The Patients With Wilson disease and Familial Hypoccerulosminemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on Presymptomatic recognition and prevention of late-onset ornithine transcarbamylase deficiency in malePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Study on Molecular Epidemiology and Prevention of Onset of Late-onset Ornithine Transcarbamylase Deficiency in Male PatientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A development of novel vectors and an establishment of a new generation of hepatic gene therapy for congenital metabolic diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanism of Localization of the Mutant Ornithine Transcarbamylase to Mitochondrial CompartmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of late onset ornithine transcarbamylase deficiency in male

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanism of Late Onset Type of Ornithine Transcarbamylase Deficiency in MalesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on the mutations at the phynylalanine hydroxylase gene among the Japanese populationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ライソゾーム病‐最新の病態、診断、治療の進歩‐（改定第2版）2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 高アンモニア血症 小児科診療ガイドライン―最新の診療指針―（第５版）2022

Author(s)

Total Pages

Publisher

Data Source

[Book] 今日の治療と看護改訂 : 第2版2004

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 小児科外来診療のコツと落とし穴5小児救急2004

Author(s)

Total Pages

Publisher

YOSHINO Makoto 芳野信

芳野信ヨシノマコト

[Book] 高アンモニア血症　小児科診療ガイドライン―最新の診療指針―（第５版）2022

[Book] 今日の治療と看護改定第2版2004