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MUKAI Tsunehiro
向井 常博
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Alternative Names
向井 常博 ムカイ ツネヒロ
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Researcher Number
40108741
Other IDs
Affiliation (based on the past Project Information)
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2005: Saga University, Director, 理事
2003 – 2004: 佐賀大学, 医学部, 教授
1997 – 2001: 佐賀医科大学, 医学部, 教授
1997: 佐賀医科大学, 医学部・生化学, 教授
1995 – 1996: 国立循環器病センター研究所, バイオサイエンス部, 部長
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1992 – 1993: 国立循環器病センター研究所, バイオサイエンス部, 部長
1988: 国立循環器病センター, バイオサイエンス部, 部長
1988: Department of Bioscience, バイオサイエンス部, 部長
1987: 佐賀医大, 医学部, 助教授
1987: 佐賀医科大学, 医学部, 助教授
1986 – 1987: 佐賀医科大学, 助教授
1986: 佐賀医大, 生化学, 助教授
1985: 佐賀医科大学, 医, 助教授
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Review Section/Research Field
Principal Investigator
Biological Sciences
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Pathological medical chemistry
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Human genetics
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General medical chemistry
/
General medical chemistry
Except Principal Investigator
Pathological medical chemistry
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Cerebral neurosurgery
/
Genetics/Genome dynamics
Keywords
Principal Investigator
インプリンティング / Beckwith-Wiedemann症候群 / DNAメチレーション / 脳型アルドラーゼ / トランスジェニックマウス / サイクリンキナーゼインヒビター / Lit1 / インプリンティングセンター / アルドラーゼ / genomic imprinting
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/ Beckwith-Wiedemann syndrome / DNA methylation / Murr1 / U2af1-rs1 / LCR(locus control regiom) / トランスジース / カルボジイミド / ビオチン / カルボジイミド-ビオチン化合物 / ミスマッチ / DNAプローブ / ゲ)ムインプリンティング / ウィルムス腫瘍 / ゲノムのインプリンティング / 腫瘍サプレッサー / p57KIP2 / Obp-rs,FISH解析 / DNAのメチル化 / p57kip2 / DNAメチル化 / p57^<kip2> / メチレーション / 溶血性貧血 / アルドラーゼA遺伝子 / アルトラーゼB遺伝子 / ゲルリタデーション / 胎児性腫瘍 / Beckwith-wiedemann症候群 / 、ベックウィズ・ウィードマン症候群 / embryonal tumor / インプリンテイング / p57^<KIP2>変異体 / p57KIP2変異体 / ゲノムインプリンティング / P57KIP2 / アデノウイルスベクター / p57Kip2 mutant / transgenic mouse / Imprinting / Imprinting center / アルドラーゼC / プルキンエ細胞 / In Situ hybridization / in situ hybridization / ID配列 / In Situ Hybridization / aldolase C / Purkinje cell
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More
Except Principal Investigator
プリン代謝 / 心筋 / 遺伝子発現 / アデニレートデアミナーゼ / AMPD / アイソザイム / cDNAクローニング / 平滑筋 / 分化 / 転写調節 / MEF2 / がん細胞 / コロニーハイブリダイゼーション / 内因性レトロウイルス / 細胞増殖因子 / 遺伝性血液疾患 / 不安定ヘモグロビン症 / サラセミア / 赤血球酵素異常症 / ピルビン酸キナーゼ異常症 / 遺伝性楕円赤血球症 / 血友病 / 慢性肉芽腫症 / IGFII / 反復配列 / 不死性獲得遺伝子 / Sー100様カルシウム結合蛋白質 / α_2ーマクログロブリン / アルドラーゼ / スプライシング / HTLVー1 / B型肝炎ウイルス / 組込み / 染色体再編成 / 肝癌発生 / がん遺伝子lca / トランスフォーメーション / 疼痛 / 異種移植 / ベータ・エンドルフィン / ポリマーカプセル / pain / xenograft / beta-endorphin / polymer capsule / AMPデアミナーゼ / アデニンスフレオチド / 遺伝子ターゲティング / アデニンヌクレオチド / クローニング / AMAP deaminase / purine metabolism / adenine nuleotide / gene targeting / heart / ゲノム刷り込み / 転写干渉 / Murr1遺伝子 / U2af1-rs1遺伝子 / Murrl遺伝子 / Genomic Imprinting / Transcriptional interference / Murr1 gene / U2af1-rs1 gene
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Research Projects
(
23
results)
Co-Researchers
(
26
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Molecular structure, evolution and mechanism of genomic imprinting
Principal Investigator
Principal Investigator
MUKAI Tsunehiro
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Saga University
Molecular mechanisms of the adult brain-specific genomic imprinting of mouse Mzrr1 gene.
Principal Investigator
JOH Keiichiro
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Genetics/Genome dynamics
Research Institution
Saga University
佐賀医科大学
細胞機能を司るゲノムDNAメチル化によるインプリンティング制御と疾患発症機構
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
2001
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
佐賀医科大学
ヒト11p15.5(セントロメア側)に対応するマウスゲノム領域の構造解析
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
佐賀医科大学
細胞機能を司るゲノムDNAメチル化の生理的動態ならびに病態解析
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
佐賀医科大学
Construction of model mouse of the Beckwith-wiedemann syndrome
Principal Investigator
Principal Investigator
MUKAI Tsunehiro
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Saga Medical School
p57KIP2遺伝子の小児腫瘍への関与の検討
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
佐賀医科大学
サイクリン依存性キナーゼインヒビターp57^<KIP2>のWilms腫瘍への関与の検討
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
佐賀医科大学
平滑筋細胞の分化におけるMEF2遺伝子群の役割の解析
Principal Investigator
森崎 隆幸
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
National Cardiovascular Center Research Institute
Molecular genetic analysis of the disease resulted from abnomal genomic imprinting
Principal Investigator
Principal Investigator
MUKAI Tsunehiro
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Saga Medical School
Functional analysis of AMPD gene family in cellular and animal models
Principal Investigator
MORISAKI Takayuki
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
National Cardiovascular Center Research Institute
アデニレートブアミナーゼ心筋型アイソザイムの遺伝子解析
Principal Investigator
MORISAKI Takayuki
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
National Cardiovascular Center Research Institute
Transplantation of encapsulated cells secreting human beta-endorphin in cerebro-spinal space for cancerpain
Principal Investigator
SAITOH Youichi
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
Osaka University
ミスマッチ変異検出を利用した未知変異遺伝子スキャンニング法の開発
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Human genetics
Research Institution
National Cardiovascular Center Research Institute
遺伝子産制御領域の同定と医学研究への応用
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
National Cardiovascular Center Research Institute
癌化に伴うアルドラーゼアイソザイムの発現転換現象の解析
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
National Cardiovascular Center Research Institute
肝癌発生とB型肝炎ウイルス増殖に関する分子生物学的研究
Principal Investigator
松原 謙一
Project Period (FY)
1987
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Structural analysis of aldolase C gene and the identification of its expressed cell in brain
Principal Investigator
Principal Investigator
MUKAI Tsunehiro
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
National Cardiovascular Center Research Institute
佐賀医科大学
がんにおける遺伝子発現の特異性
Principal Investigator
遠藤 英也
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kyushu University
遺伝性血液疾患の病因解析
Principal Investigator
三輪 史朗
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Special Project Research
Research Institution
The University of Tokyo
癌化に伴うアルドラーゼアイソザイムの発現型転換現象の解析
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1985
Research Category
Grant-in-Aid for Cancer Research
Research Institution
佐賀医科大学
アルドラーゼ欠損症の遺伝生化学的研究
Principal Investigator
Principal Investigator
向井 常博
Project Period (FY)
1985
Research Category
Grant-in-Aid for Special Project Research
Research Institution
佐賀医科大学
がんにおける遺伝子発現の特異性
Principal Investigator
遠藤 英也
Project Period (FY)
1985 – 1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kyushu University
# of Projects (Dsc)
# of Projects (Asc)
1.
JOH Keiichiro
(90124809)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
2.
SOEJIMA Hidenobu
(30304885)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
MORISAKI Takayuki
(30174410)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
HIDAKA Kyoko
(00216681)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
荒井 勇二
(30202724)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
遠藤 英也
(40037320)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
榊 佳之
(10112327)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
高野 利也
(60051364)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
SAITOH Youichi
(20252661)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
IWATA Hiroo
(30160120)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
OHNISHI Takanori
(70233210)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
HAYAKAWA Toru
(20135700)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
MORISAKI Hiroko
(40311451)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
山本 三毅夫
(60037447)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
畑中 正一
(30142300)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
三輪 史朗
(40034954)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
八幡 義人
(70069011)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
田中 武彦
(60028272)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
米山 良昌
(10019515)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
宮地 隆興
(60034906)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
牧 正敏
(40183610)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
大島 靖美
(90037606)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
松原 謙一
(20037394)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
三輪 正直
(20012750)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
千坂 修
(80188474)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
NATSUME Toru
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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