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YASUDA Hideyo
安田 秀世
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Alternative Names
安田 英世 ヤスダ ヒデヨ
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Researcher Number
40111554
External Links
Affiliation
*help
2016 – 2018 : 聖マリアンナ医科大学, 医学研究科, 教授
2005 : 日本製粉株式会社中央研究所, 生物科学研究所, 所長
2004 : 日本製粉株式会社中央研究所, 生物科学研究部, 研究部長
2002 : 東京薬大, 生命科学部, 教授
1994 – 2001 : 東京薬科大学, 生命科学部, 教授
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1995 : KANAZAWA UNIVERSITY FACULTY OF PHARM.SCI.ASSOCIATE PROFESSOR, 薬学部, 助教授
1986 – 1993 : 金沢大学, 薬学部, 助教授
1986 : 金沢大, 薬学部, 助教授
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Review Section/Research Field
Principal Investigator
Biological pharmacy
/
Biological Sciences
/
分子細胞生物学
Except Principal Investigator
放射線5生物学
/
Functional biochemistry
/
Biological pharmacy
/
Biological Sciences
Keywords
Principal Investigator
細胞周期 / p53 / ユビキチン / cdk2 / サイクリン / MDM2 / 14-3-3 / wee1キナーゼ / PIAS / 転写因子
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More
/ 温度感受性変異株 / cdc2キナーゼ / 癌抑制遺伝子 / cdk / サイクリンB / Cell cycle / cdc2 kinase / スモ化 / HIヒストン / H1ヒストン / 翻訳後修飾 / 染色体凝縮 / SUMO / cdc2キナ-ゼ / リン酸化 / cyclin / ヒストン / myt1キナーゼ / cell cycle / 分裂期 / DNA合成 / AP1 / _3T_3細胞 / ts変異株 / weelキナーゼ / チミジン枯渇 / Histone / MOM2 / cdK / MDMX / サイクロソーム / オカダ酸 / SUMO-1 / クロマチン / cdc変異株 / tsTM13 / Cdc2 kinase / phosphorylation / 燐酸化酵素 / APC / Ba1b / 転写制御 / プロテアソーム / NRK細胞 / がん抑制遺伝子 / 多核細胞 / H1ヒストンリン酸化酵素 / サイクリン依存性キナーゼ / E3 / E2 / HIヒストンリン酸化酵素 / PEA3 / 核移行 / ヒストン小成分 / cdc25 / DNA依存性タンパク質りん酸化酵素 / リングフィンガー / weel kinase / Temperature sensitive mutant / Balb / Cut2 / 高速液体クロマトグラフィー / Rb蛋白質 / フォスファターゼ / ユビキチンリガーゼ / クローニング / Okadaic acid / Maturation / SOX9 / 成熟 / p73 / weel / c3T3細胞 / 細胞質分裂 / Hl histone kinase / Hl histone / モノクローナル抗体
…
More
Except Principal Investigator
細胞周期 / ユビキチン / プロテアソーム / 蛋白質分解 / RPN5 / RPN6 / RPN7 / DNA損傷 / 核小体 / 出芽酵母 / 染色体異常 / 哺乳動物細胞 / リン酸化 / 形質転換能 / RPN8 / RPN9 / 温度感受性 / 26S proteasome / Cdc14フォスファスーゼ / 阻害剤 / G2 / サイクリンB / Cell cycle / 突然変異株 / SPB / ベース / SUMO-1 / AT細胞 / Cell death / ユビキチンワールド / 動物細胞 / 過酸化水素 / MDM2 / 放射性壊変 / UBC9 / 哺乳類培養細胞株 / 細胞死 / ユビキチン活性化酵素 / 染色体 / チミジル酸ストレス / トリチウム水 / M期後期開始 / 蛋白質リン酸化 / 19S reguratory comoplex / NF-κB / Kinase / DNA Repair / 遺伝子導入 / 蛋白質のリン酸化 / 鎖切断 / サザン解析 / cDNAトランスフェクション / 染色体凝縮 / スピンドルチェックポイント / Regulation of transcription / base / 遺伝子構造 / 放射線感受性 / IκB / 〔2ー^<14>C,5ー^3H〕ウラシル / ユビキチン様蛋白質 / リッド / サブユニット集合 / ユビキチン代謝 / 転写調節 / 融合細胞 / ユビキチン・プロテアソーム系 / パン酵母 / Radiosensitivity / 培養細胞 / Cdc14 / ストレス応答 / M期終了 / 温度感受性変異株 / p53 / Cultured cells / DNA / 蛋白質の脱リン酸化 / リン酸化酵素 / Gene transfer / 19S調節因子 / DNA damage / 脱ユビキチン化 / ユビキチンリガーゼ / MEN / リボゾームRNA / 26Sプロテアソーム / Tem1 / DNA修復 / マウス細胞 / Ataxia telangiectasia / lid / baker's yeast / 線量率依存 / トリチウム照射 / H1ヒストン / アタキシア細胞 / RBE / 低線量率 / X線感受性 / サイクリン / 局在 / 分裂期 / 温度感受性変異 / サイクリン蛋白質 / Mアレスト / 主鎖切断
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Research Projects
(
32
results)
Research Products
(
2
results)
Co-Researchers
(
29
People)
Project Start Year(Newest)
Project Start Year(Oldest)
p53、p51、MDM2のSUMO化による制御機構
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
2004
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Central Laboratory, Nippon Flour Mills Co., Ltd.
p53のユビキチンリガーゼMDM2の活性制御機構
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Central Laboratory, Nippon Flour Mills Co., Ltd.
翻訳後修飾によるMDM2の活性制御機構
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
2002
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Tokyo University of Pharmacy and Life Science
リングフィンガー型ユビキチンリガーゼ活性を持つがん遺伝子産物の研究
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
2001
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Tokyo University of Pharmacy and Life Science
Cell cycle regulation by protein degradation and transport
Principal Investigator
TOH-E Akio
Project Period (FY)
2001 – 2005
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
The University of Tokyo
ユビキチン化、SUMO-1化によるp53の活性制御機構
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Tokyo University of Pharmacy and Life Science
ユビキチンワールド:新しい生体反応制御システム
Principal Investigator
横沢 英良
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Hokkaido University
p53のユビキチン経路における分解
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo University of Pharmacy and Life Science
細胞機能を制御する蛋白質ユビキチン化の機構解明
Principal Investigator
本多 玲子
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo University of Pharmacy and Life Science
IκBのユビキチンリガーゼの同定
Principal Investigator
早川 磨紀男
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo University of Pharmacy and Life Science
サイクリンBに特異的なユビキチンリガーゼの解析
Principal Investigator
田中 弘文
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo University of Pharmacy and Life Science
哺乳類細胞の分裂期染色体凝縮、脱凝縮の制御機構
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Pharmacy and Life Science
哺乳動物細胞におけるサイクリンB特異的ユビキチン化とその調節機構の解明
Principal Investigator
田中 弘文
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Pharmacy and Life Science
分裂期染色体の脱凝縮を制御する遺伝子の解明
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Pharmacy and Life Science
チミジン枯渇ストレスを利用した哺乳類cdc-ts変異株の単離
Principal Investigator
Principal Investigator
安田 英世
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Biological pharmacy
Research Institution
Tokyo University of Pharmacy and Life Science
分裂期染色体の脱凝縮の制御機構
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Pharmacy and Life Science
細胞質分裂に必須な遺伝子の単離
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Pharmacy and Life Science
Regulation Mechanism of Cyclin Dependent Kinase Activity in Mammalian Cells
Principal Investigator
Principal Investigator
YASUDA Hideyo
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCE
The transcription factor of cyclin-dependent kinase 2 (cdk2) gene.
Principal Investigator
OHBA Yoshiki
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
KANAZAWA UNIVERSITY
ユビキチンサイクルが支配するがん細胞の増殖と染色体不安定化
Principal Investigator
瀬野 悍二
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
National Institute of Genetics
ユビキチンサイクルが支配するがん細胞の増殖と染色体不安定化
Principal Investigator
瀬野 悍二
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
National Institute of Genetics
DNA複製制御におけるサイクリン依存性キナーゼ(cdk)の役割
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kanazawa University
Mechanism of Regulation of Cdks's Activity
Principal Investigator
Principal Investigator
YASUDA Hideyo
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
分子細胞生物学
Research Institution
Kanazawa University
ユビキチンサイクルが支配するがん細胞の増殖と染色体不安定化
Principal Investigator
瀬野 悍二
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
National Institute of Genetics
染色体凝縮制御におけるcdc2キナ-ゼの役割
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kanazawa University
The Purification of Mammlian H1 Thistone Kinase and Regulation of its Activty
Principal Investigator
Principal Investigator
YASUDA Hideyo
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University, Faculty of Pnarmaceutical Sciences
がん細胞における染色体の不安定化と再配列に関与する因子の分子遺伝学的研究
Principal Investigator
瀬野 悍二
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
National Institute of Genetics
トリチウム水による核酸損傷の分子構造
Principal Investigator
高倉 かほる
Project Period (FY)
1987
Research Category
Grant-in-Aid for Fusion Research
Research Institution
International Christian University
The cloning and expression of the gene of Hl histone, which is expressed at GO phase
Principal Investigator
Principal Investigator
YASUDA Hideyo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
トリチウム水による核酸損傷の分子構造
Principal Investigator
高倉 かほる
Project Period (FY)
1986
Research Category
Grant-in-Aid for Fusion Research
Research Institution
International Christian University
モノクローナル抗体をもちいた,HIヒストンのクロマチン構造の調節に関する研究
Principal Investigator
Principal Investigator
安田 秀世
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kanazawa University
Characterization of X-ray-sensitive cells and isolation of the gene responsible for their radiosensitivity.
Principal Investigator
SAKAI Kazuo
, 岡田 重文
Project Period (FY)
1985 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
放射線5生物学
Research Institution
Faculty of Medicine, University of Tokyo
All
2004
All
Journal Article
[Journal Article] Sumoylation of Tumor Suppressor p53
2004
Author(s)
Yasuda, H
Journal Title
SUMOYLATION Molecular biology and Biochemistry
Pages
: 379-396
Data Source
KAKENHI-PROJECT-16022269
[Journal Article] Sumoylation of Tumor Suppressor p53
2004
Author(s)
Yasuda, H
Journal Title
SUMOYLATION Molecular biology and Biochemistry
Pages
: 379-396
Data Source
KAKENHI-PROJECT-16026252
# of Projects (Dsc)
# of Projects (Asc)
1.
瀬野 悍二
(30076989)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
2.
辻 秀雄
(40163795)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
3.
田中 弘文
(30146899)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
4.
OHBA Yoshiki
(10012634)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
5.
鮎沢 大
(00142109)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
6.
SAKAI Kazuo
(40153837)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
7.
山尾 文明
(10158074)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
8.
松本 邦弘
(70116375)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
9.
本多 玲子
(20277255)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
10.
高倉 かほる
(80052281)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
11.
朝野 武美
(30100176)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
12.
石川 光男
(30052244)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
13.
TOH-E Akio
(90029249)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
14.
SUZUKI Norio
(10010050)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
15.
石田 良司
(50150214)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
16.
安藤 俊夫
(20012693)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
17.
綿矢 有佑
(90127598)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
18.
花岡 文雄
(50012670)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
19.
杉本 勝則
(90192616)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
20.
早川 磨紀男
(30198824)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
21.
横沢 英良
(90012765)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
22.
小南 欽一郎
(80304830)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
23.
岩井 一宏
(60252459)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
24.
木南 英紀
(10035496)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
25.
千葉 智樹
(00311423)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
長谷川 圀彦
(90021948)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
菊池 淑子
(00138124)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
吉田 稔
(80191617)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
岡田 重文
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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