KUROKI Masahide 黒木政秀

Researcher Number	40122692
Other IDs
External Links
Affiliation *help	2014 : 福岡大学, 医学部, 教授 1998 – 2010 : 福岡大学, 医学部, 教授 1998 – 2009 : 福岡大, 医学部, 教授 1995 : Fukuoka Univ., School of Medicine, Professor, 医学部・生化学第一教室, 教授 1994 : 福岡大学, 医学部, 教授 1986 – 1990 : 福岡大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Laboratory medicine / Laboratory medicine / Medical systems Except Principal Investigator Digestive surgery / Pathological medical chemistry
Keywords	Principal Investigator ADCC / 腫瘍関連抗原 / CDC / モノクローナル抗体 / tumor-associated antigen / monoclonal antibody / MK-1 / 17-1A / Ep-CAM / CEA … More Except Principal Investigator CEA / アデノウイルス / Nucleus tractus solitarii / 低交差反応性抗体産生クローンの選択 / gene therapy / ニューロキニンA特異抗血清 / 抗ニューロキニンB特異抗血清 / 抗サブスタンスK特異抗血清 / ニューロキニンBの脳内分布 / サブスタンスKとニューロキニンBの分別定量 / D-GL / 遺伝子治療 / 特異抗ニューロキニンB抗血清 / プロソマトスタチンのプロセシング / Specific anti-neurokinin A antiserum / Production of site-specific antibody / adenovirus / モノクロ-ナル抗体 / 低交差反応性抗体作製法 / Eck瘻犬の脳内cckの減少 / Distribution of neurokinin A and neurokinin B / 高血圧とニューロキニンB / 抗サブスタンスK特異抗体 / 胃癌 / 特異抗ニューロキニンA抗血清 / 腫瘍マ-カ- / -GL / gastric cancer / 抗ソマトスタチン28(1-12)抗体 / 抗体 / 癌特異性 / 脳内ソマトスタチン28(1-12)濃度とソマトスタチン-14濃度の相関 / 癌特異的抗原性 / glycolipid anchor / ニューロキニンB特異抗血清 / Eck瘻犬の脳内ソマトスタチンの減少 / 大腸粘膜上皮細胞 / 正常糞便抗原 / 正常大腸粘膜のCEA産生 / 癌胎児性抗原 / 抗原決定基 / GPI型膜結合 / ニューロキニンAの脳内分布 / NCA / Specific anti-neurokinin B antiserum / antibody Less

光感受性物質IR700を結合したヒト抗腫瘍抗体を用いる近赤外線免疫療法の確立Principal Investigator
- Principal Investigator
  
  黒木政秀
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Fukuoka University
Study on the Usefulness of the Novel Tumor Marker MK-1 in the Diagnosis and Therapy of CancerPrincipal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
Generation and application of fully human antibodies to a new tumor-associated antigen, Ep-CAMPrincipal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
Targeted therapy of gastrointestinal cancer using human anti-CEA antibody
- Principal Investigator
  
  TANAKA Toshihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukuoka University
  Sapporo Medical University
Significance of a new tumor-associated antigen, MK-1, for diagnosis and therapy of cancerPrincipal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
Generation, immunologic characterization and antitumor effects of human monoclonal antibodies for carcinoembryonic antigenPrincipal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
A Specific Study for Clinical Application of a New Tumor-associated Antigen, MK-1,Principal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
The analysis of a new tumor-associated antigen, TSP-1, in the gene and protein expression levelsPrincipal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
Cloning of cDNA and establishment of an assay system for Mr 110,000 AgPrincipal Investigator
- Principal Investigator
  
  KUROKI Masahide
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukuoka University
粘膜上皮細胞の分化並びに癌化に伴うCEA及び関連抗原の産生動態の変化
- Principal Investigator
  
  松岡雄治
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fukuoka University
癌胎児性抗原(CEA)の癌特異性の本態の解明
- Principal Investigator
  
  松岡雄治
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fukuoka University
Preparation of site-specific antibodies by a novel immunization procedure involving induction of tolerance to cross-reacting determinants and its utilization
- Principal Investigator
  
  TATEISHI Kayoko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Fukuoka University

All 2014 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Peptide Science 20092010
- Author(s)
  Mizoe, Y., Shioi, N., Terada, S., Uchida, Y., Kuroki, M, Lee, S.
- Total Pages
  491
- Publisher
  The Japanese Peptide Society(Osaka)
- Data Source
  KAKENHI-PROJECT-20590593
[Book] Peptide Science 2009.(K.Okamoto, ed.)(Characteristic difference of biological activity between Arg-containing and Lys-containing peptide.)2010
- Author(s)
  Mizoe Y., Shioi N., Terada S., Uchida Y., Kuroki Ma., Lee S.
- Publisher
  The Japanese Peptide Society Fukuoka
- Data Source
  KAKENHI-PROJECT-20590593
[Book] Methods in Molecular Biology(U.Reineke and M.Schutkowski, eds.)(Vol.524, Epitope Mapping Protocols, A solid-phase mutual inhibition assay with labeled antigen.)2009
- Author(s)
  Kuroki Ma.
- Publisher
  Humana Press Totowa NJ
- Data Source
  KAKENHI-PROJECT-20590593
[Book] Methods in Molecular Biology2009
- Author(s)
  Kuroki, M.
- Total Pages
  426
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20590593
[Book] Methods in Molecular Biology2009
- Author(s)
  Kuroki, Ma.
- Total Pages
  7
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20590593
[Book] Recent Developments in Immunology(J.Xiang, ed.)(Fusion therapy of cellular and humoral immunity for cancer using antibodies or their genes against carcinoembryonic antigen.)2008
- Author(s)
  Kuroki Ma., Wang L., Huo Q., Shibaguchi H., Yanagisawa J., Fukami T., Yotsumoto F., Tanaka T., Miyamoto S.
- Publisher
  Transworld Research Network Kerala India
- Data Source
  KAKENHI-PROJECT-20590593
[Book] Recent Developmentsin Gene Therapy(J.Xiang, ed.)2007
- Author(s)
  Tanaka, T., Hamada, H., Kuroki, Mo., Kato, K., Kinugasa, T., et. al.
- Total Pages
  367
- Publisher
  Tlransworld Research Network
- Data Source
  KAKENHI-PROJECT-18590544
[Book] Recent Developments in Gene Therapy2007
- Author(s)
  Tanaka, T., Hamada, H., Kuroki, Mo., Kato, K., et. al.
- Total Pages
  367
- Publisher
  Transworld Research Network
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Book] Recent Development in Gene Therapy2007
- Author(s)
  Tanaka T, Hamada H, Kuroki Ma, et al.
- Publisher
  RANSWORLD RESERCH NETWORK
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Book] Recent Development in Gene Therapy
- Author(s)
  Tanaka T, Hamada H, Kuroki Ma, et al.
- Publisher
  RANSWORLD RESERCH NETWORK(In press)
- Data Source
  KAKENHI-PROJECT-17591421
[Book] Ransworld Reseaech Network
- Author(s)
  Tanaka, T, Hamada, H, Kuroki, M, Kato K.et al.
- Publisher
  Ransworld Research Network(in press)
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Fractionated radioimmunotherapy with 90Y-labeled fully human anti-CEA antibody.2014
- Author(s)
  Hanaoka H, Kuroki M, Yamaguchi A, Achmad A, Iida Y, Higuchi T, Oriuchi N, Endo K
- Journal Title
  
  Cancer Biotherapy & Radiopharmaceuticals
  
  Volume : 29 Pages : 70-76
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591809, KAKENHI-PROJECT-26350553, KAKENHI-PROJECT-24659573
[Journal Article] Potent and specific antitumor effect of CEA-targeted photoimmunotherapy2014
- Author(s)
  Shirasu N, Yamada H, Shibaguchi H, Kuroki M, Kuroki M
- Journal Title
  
  International Journal of Cancer
  
  Volume : 135 Pages : 2697-2710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350553, KAKENHI-PROJECT-26830119
[Journal Article] Novel treatment strategies for cancer and their tumor-targeting approaches using antibodies against tumor-associated antigens2014
- Author(s)
  Kuroki M, Shirasu N
- Journal Title
  
  Anticancer Research
  
  Volume : 34 Pages : 4481-4488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350553
[Journal Article] CEA特異的なヒト単鎖型抗体遺伝子のクローニングとキメラT細胞受容の作製2011
- Author(s)
  白須直人,芝口浩智,黒木求,山田博美,黒木政秀
- Journal Title
  
  日本分子腫瘍マーカー研究会誌 26
  
  Pages : 26-27
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Emerging strategies for ErbB ligand-based targeted the rapy for cancer2010
- Author(s)
  Tsujioka, H., Yotsumoto, F., Shirota, K., Horiuchi, S., Yoshizato, T., Kuroki, Ma., et al.
- Journal Title
  
  Anticancer Research
  
  Volume : 30 Pages : 3107-3112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Amphiregulin regulates the activation of ERK and Akt through EGFR and HER3 signals involved in the progression of pancreatic cancer2010
- Author(s)
  Yotsumoto, F., Fukami, T., Yagi, H., Funakosi, A., Yoshizato, T., Kuroki, Ma., et al.
- Journal Title
  
  Cancer Science
  
  Volume : 101 Pages : 2351-2360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Amphiregulin regulates the activation of ERK and Akt through EGFR and HER3 signals involved in the progression of pancreatic cancer.2010
- Author(s)
  Yotsumoto F., Fukami T., Yagi H., Funakosi A., Yoshizato T., Kuroki Ma, Miyamoto S.
- Journal Title
  
  Cancer Sci. 101(11)
  
  Pages : 2351-2360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Construction and molecular characterization of human chimeric T cell antigen receptors specific for carcinoembryonic antigen.2010
- Author(s)
  Shirasu N., 芝口浩智, Kuroki Mo., Yamada H., Kuroki Ma.
- Journal Title
  
  Anticancer Res. 30(7)
  
  Pages : 2731-2738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] HB-EGF orchestrates the signals involved in triple-negative and trastuzumab-resistant breast cancer.2010
- Author(s)
  Yotsumoto F., Oki E., Tokunaga E., Maehara Y., Kuroki Ma., Hiroto Mizushima H., Mekada E., Miyamoto S.
- Journal Title
  
  Int.J.Cancer 127(11)
  
  Pages : 2707-2717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] HB-EGF orchestrates the signals illvolved in triple-negative and trastuzumab-resistant breast cancer2010
- Author(s)
  Yotsumoto, F., Oki, E., Tokunaga, E., Maehara, Y., Kuroki, Ma., et al.
- Journal Title
  
  International Journal of Cancer
  
  Volume : 127 Pages : 2707-2717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Claudin-1 protein is a major factor involved in the tumorigenesis of colorectal cancer.2009
- Author(s)
  Huo Q., Kinugasa T., Wang L., Huang J., Shibaguchi H, Kuroki Mo., Tanaka T., Yamashita Y., Nabeshima K., Iwasaki H, Kuroki Ma
- Journal Title
  
  Anticancer Res. 29(3)
  
  Pages : 851-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Recent developments in cancer gene therapy with adenovirus vectors.2009
- Author(s)
  Tanaka T., Shibaguchi H., Maekawa S., Shimura H., Tamura K., Kuroki Ma.
- Journal Title
  
  Trends Cancer Res. 5(1)
  
  Pages : 63-69
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Engineering T cells in cancer immunotherapy : strategy for gene construction and antitumor activity.2009
- Author(s)
  Shibaguchi H., Tanaka T., Luo N., Kuroki Ma.
- Journal Title
  
  Trends Cancer Res. 5(1)
  
  Pages : 21-27
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] FU-MK-1 expression in human gallbladder carcinoma : An antigenic prediction marker for a better postsurgical prognosis.2009
- Author(s)
  Ikeda T., Nakayama Y., Hamada Y., Takeshita M., Iwasaki H., Maeshiro K., Yamashita Y., Kuroki Ma., Ikeda S.
- Journal Title
  
  Am.J.Clin.Pathol. 132(1)
  
  Pages : 111-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Amphiregulin regulates the production of human chorionic gonadotropin in trophoblasts.2009
- Author(s)
  Fukami T, Yoshizato T, Miyamoto S, Yagi H, Yotsumoto F, Nabeshima K, Hachisuga T, Kuroki Ma, Kawarabayashi T
- Journal Title
  
  Life Sci. 84(23-24)
  
  Pages : 796-804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor HB-EGF, in ovarian cancer.2009
- Author(s)
  Yagi H., Yotsumoto F., Sonoda K., Kuroki Ma., Mekada E., Miyamoto S.
- Journal Title
  
  Int.J.Cancer 124(6)
  
  Pages : 1429-1439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Recombinant human monoclonal IgA antibody against CEA to recruit neutrophils to CEA-expressing cells.2008
- Author(s)
  Zhao J., Kuroki Mo., Shibaguchi H., Wang L., Huo Q., Takami N., Tanaka T., Kinugasa T., Kuroki Ma.
- Journal Title
  
  Oncol.Res. 17
  
  Pages : 217-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Tumor targeting carboxylesterase fused with anti CEA scFv improve the anticancer effect with a less toxic dose of irinotecan.2008
- Author(s)
  Uchino J., Takayama K., Harada A., Sone T., Harada T., Curiel D.T., Kuroki Ma., Nakanishi Y.
- Journal Title
  
  Cancer Gene Ther. 15
  
  Pages : 94-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Recombinant human monoclonal IgA antibody against CEA to recruit neutrophils to CEA -expressing cells2008
- Author(s)
  Zhao, J., Kuroki, Mo., Shibaguchi, H., et al.
- Journal Title
  
  Oncol. Res. 17
  
  Pages : 217-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590593
[Journal Article] Correlation between lymph node metastasis and expression of TEGF-C, VEGF-D and VEGFR-3 in T1 lung adenocarcinoma2007
- Author(s)
  Maekawa, S., Iwasaki, A., Enatsu, S., Kawakami, T., Kuroki, Mo., et. al.
- Journal Title
  
  Anticancer Res. 27
  
  Pages : 3755-3741
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Sonodynamic therapy of cancer using a novel porphyrin derivative, DCPH-P-Na (I), which is devoid of photosensitivity2007
- Author(s)
  Hachimine, K., Shibaguchi, H., Kuroki, Mo., Yamada, H., et. al.
- Journal Title
  
  Cancer Sci. 98
  
  Pages : 916-920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Correlation between lymph node metastasis and expression of VEGF-C,VEGF-D and VEGFR-3 in T1 lung adenocarcinoma2007
- Author(s)
  Maekawa, S., Iwasaki, A., Enatsu, S., Kawakami, T., Kuroki, Mo., et. al.
- Journal Title
  
  Anticancer Res. 27
  
  Pages : 3755-3741
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Sonodynamic therapy of cancer using a novel porphyrin derivative,DCPH-P-Na(I),which is devoid of photosensitivity2007
- Author(s)
  Hachimine, K., Shibaguchi, H., Kuroki, Mo., Yamada, H., et. al.
- Journal Title
  
  Cancer Sci. 98
  
  Pages : 916-920
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Sonodynamic therapy of cancer using a novel porphyrin derivative,DCPH-PNa(I),which is devoid of photosensitivity2007
- Author(s)
  Hachimine, K., Shibaguchi, H., Kuroki, Mo., Yamada, H., et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages : 916-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Correlation between lymph node metastasis and expression of VEGF-C,VEGF-D and VEGFR-3 in T1 lung adenocarcinoma2007
- Author(s)
  Maekawa, S., Iwasaki, A., Enatsu, S., Kawakami, T., Kuroki, Mo, et. al.
- Journal Title
  
  Anticancer Res 27
  
  Pages : 3755-3741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Possible applications of antibodies or their genes in cancer therapy2006
- Author(s)
  Kuroki, M., Huang, J., Shibaguchi, H., Zhao, J., et. al.
- Journal Title
  
  Anticancer Res. 26
  
  Pages : 4019-4026
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] CEA-targeted selective gene therapy for gastric cancer through FZ33 fiber modified adenovirus vector2006
- Author(s)
  Tanaka, T., Huang, J., Hirai, S., Kuroki, Mo., et. al.
- Journal Title
  
  Clin. Cancer Res. 12
  
  Pages : 3803-3813
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Cancer Immunotherapy with Chimeric Immune Receptors (CIRs) : A Focus on Their Antitumor Activity.2006
- Author(s)
  Shibaguchi H, Tanaka T, Kuroki Ma, et al.
- Journal Title
  
  Med.Bull.Fukuoka Univ. 33(3)
  
  Pages : 243-249
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Carcinoembryonic antigen-targeted selective gene therapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006
- Author(s)
  Tanaka T, Kuroki Ma, Hamada H, et al.
- Journal Title
  
  Clin.Cancer Res. 12(12)
  
  Pages : 3803-3813
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Cancer Immunotherapy with Chimeric Immune Receptors (CIRs) : A Focus on Their Antitumor Activity.2006
- Author(s)
  Shibaguchi H, Tanaka T, Kuroki Ma, et al.
- Journal Title
  
  Med. Bull. Fukuoka Univ. 33(3)
  
  Pages : 243-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Carcinoembryonic antigen-targeted selective gene therapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006
- Author(s)
  Tanaka T, Kuroki Ma, Hamada H, et al.
- Journal Title
  
  Clin. Cancer Res. 12(12)
  
  Pages : 3803-3813
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Possible applications of antibodies or their genes in cancer therapy.2006
- Author(s)
  Kuroki Ma, Tanaka T, et al.
- Journal Title
  
  Anticancer Res. 26(6)
  
  Pages : 4019-4026
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] CEA-targeted selective gene therapy for gastric cancer through FZ33 fiber modified adenovirus vector2006
- Author(s)
  Tanaka, T., Huang, J., Hirai, S., Kuroki, Mo., et. al.
- Journal Title
  
  Clin.Cancer Res. 12
  
  Pages : 3803-3813
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] Possible applications of antibodies or their genes in cancer2006
- Author(s)
  Kuroki, M, Huang, J, Shibaguchi, H, Zhao, J.et al.
- Journal Title
  
  Anticancer Res Cancer Res. 26・6
  
  Pages : 4019-4026
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] CEA-targeted slective gene therapy for gastric cancer through FZ33 fiber modified adenovirus vector2006
- Author(s)
  Tanakja, T, Huang, J, Hirai, S, kuroki, Mo.et al.
- Journal Title
  
  Clin.Cancer Res. 12・12
  
  Pages : 3803-3813
- Data Source
  KAKENHI-PROJECT-18590544
[Journal Article] CEA-targeted Selective Gene Therapy for Gastric Cancer Through FZ33 Fiber Modified Adenovirus Vectors.2006
- Author(s)
  Tanaka T, Jianhua Huang, Hirai S, Kuroki Mo, Kuroki Ma, Watanabe N, Tomihara K, Kato K, Hamada H
- Journal Title
  
  Clin Can Res. (in press)
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Possible applications of antibodies or their genes in cancer therapy.2006
- Author(s)
  Kuroki Ma.
- Journal Title
  
  Anticancer Res. 26(6)
  
  Pages : 4019-4026
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Re-targeting of cytotoxic T lymphocytes and/or natural killer cells to CEA-expressing tumor cells with anti-CEA antibody activity.2005
- Author(s)
  Kuroki, Ma., Hachimine, K., Huang J., Shibaguchi, H., Kinugasa, T., Maekawa, S., Kuroki, Mo.
- Journal Title
  
  Anticancer Res. 25(6)
  
  Pages : 3725-3732
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Targeting of cancer gene therapy with antibodies or their genes against tumor-associated antigens.2005
- Author(s)
  Kuroki, Ma., Shibaguchi, H., Kuroki, Mo., Kinugasa, T., Hachimine, K., Enatsu, S., Maekawa, S., Huang, J., Zhao, J.
- Journal Title
  
  Gene Ther.Mol.Biol. 9(A)
  
  Pages : 107-112
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Targeting of cacner gene therapy with antibodies or their genes against tumor-associated antigens.2005
- Author(s)
  Kuroki Ma, et al.
- Journal Title
  
  Gene Ther. Mol. Biol. 9(A)
  
  Pages : 107-112
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Journal Article] Targeting of cancer gene therapy with antibodies or their genes against tumor-associated antigens.2005
- Author(s)
  Kuroki M.
- Journal Title
  
  Gene Ther.Mol.Biol. 9(A)
  
  Pages : 107-112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591421
[Presentation] Secreted production of bifunctional sc-Fv antibody-based fusion protein of IL-2 and FU-MK-1(VH-Vκ)in Pichia pastoris.2011
- Author(s)
  Anuleechan, S., Palaga, T., Kuroki, Mo., Kuroki, Ma., Chanprateep, S.
- Organizer
  Nano in Cancer : Linking Chemistry, Biology, and Clinical Applications In Vivo
- Place of Presentation
  マイアミ (アメリカ)
- Year and Date
  2011-01-14
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Production of bifunctional sc-Fv antibody-based fusion proteins of IL-2/FU-MK-1(VH-Vκ) and IL-2/FU-MK-1(Vκ-VH) in Escherichia coli, Nano in Cancer : Linking Chemistry, Biology, and Clinical Applications In Vivo2011
- Author(s)
  Chanprateep S., Kongchanasombat M., Pohthisoong N., Kuroki Mo., Kuroki Ma.
- Place of Presentation
  Miami, Florida
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Secreted production of bifunctional sc-Fv antibody-based fusion protein of IL-2 and FU-MK-1(VH-VK) in Pichia pastoris, Nano in Cancer : Linking Chemistry, Biology, and Clinical Applications In Vivo2011
- Author(s)
  Anuleechan S., Palaga T., Kuroki Mo., Kuroki Ma., Chanprateep S.
- Place of Presentation
  Miami, Florida
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Enhancement of antitumor activity in the combination therapy of anticancer dug and a fully human antibody specific for CEA is involved in CDC and ADCC, but not anoikis.2010
- Author(s)
  Shibaguchi H., Tsuru H., Kuroki Mo., Kuroki Ma.
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  Kobe (Japan)
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Development of molecularly targeted against HB-EGF for proteins with ovarian cancer.2010
- Author(s)
  Miyamoto S., Yotsumoto F., Kuroki Ma.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Construction and functional analyaia of human chimeric T cell antigen receptors specific for carcinoembryonic antigen.2010
- Author(s)
  Shirasu N., Shibaguchi H., Kuroki Mo., Yamada H., Kuroki Ma.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Identification of genes regulating of HB-EGF as a target for breast cancer therapy.2010
- Author(s)
  Yotsumoto F., Kuroki Ma., Miyamoto S.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Heparin-binding epidermal growth factor-like growth factor as a target molecule for triple negative breast cancer therapy.2009
- Author(s)
  Yotsumoto F., Oki E., Tokunaga E., Maehara Y., Sanui A., Fukami T., Kuroki Ma., Mizushima H., Mekada E., Miyamoto S.
- Organizer
  37th Meeting of the International Society of Oncology and BioMarkers (ISOBM)
- Place of Presentation
  Amsterdam (The Netherlands)(Oral)
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] HB-EGF as a target molecule for triple negative breast cancer therapy.2009
- Author(s)
  Yotsumoto F., Oki E., Tokunaga E., Maehara Y., Sanui A., Fukami T., Kuroki Ma., Mizushima H., Mekada E., Miyamoto S.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Combination therapy of gastric cancer using a human antibody to CEA and anticancer drugs.2008
- Author(s)
  Shibaguchi H., Tsuru H., Kuroki Mo., Tanaka T., Kuroki Ma.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Efficacy of cross-reacting material 197 (CRM197), a specific inhibitor for heparin-bindingepidermal growth factor-like growth factor (HB), in breast cancer patients.2008
- Author(s)
  Yotsumoto F., Oki E., Tokunaga E., Maehara Y., Kuroki Ma., Mizushima H., Mekada E., Miyamoto S.
- Organizer
  36th Meeting of the International Society of Oncology and BioMarkers (ISOBM)
- Place of Presentation
  Tokyo (Japan)
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] The validation of CRM197, a specific inhibitor for HB-EGF, for molecularly targeted in breast cancer patients.2008
- Author(s)
  Yotsumoto F., Oki E., Tokunaga E., Maehara Y., Kuroki Ma., Mizushima H., Mekada E., Miyamoto S.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Synergistic anti-tumor effects in combination of Gemcitabine with inhibitors for amphiregulin.2008
- Author(s)
  Fukami T., Yagi H., Yotsumoto F., Funakoshi A., Kuroki Ma., Mekada E., Miyamoto S.
- Organizer
  99th Annual Meeting of the American Association for Cancer Research (AACR)
- Place of Presentation
  San Diego (USA)
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Phase I study of BK-UK (CRM197) in patients with ovarian cancer.2008
- Author(s)
  Miyamoto S., Yotsumoto F., Fukami T., Sanui A., Kuroki Ma., Mekada E.
- Organizer
  36th Meeting of the International Society of Oncology and BiolMarkers (ISOBM)
- Place of Presentation
  Tokyo (Japan)
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Heparin-binding epidermal growth factor-like growth factor (HB) regulates mammary tumorigenesis through EGFR as well as Her2 signal.2008
- Author(s)
  Yotsumoto F., Yagi H., Fukami T., Kuroki Ma., Mizushima H., Mekada E., Miyamoto S.
- Organizer
  99th Annual Meeting of the American Association for Cancer Research (AACR)
- Place of Presentation
  San Diego (USA)
- Data Source
  KAKENHI-PROJECT-20590593
[Presentation] Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer2007
- Author(s)
  衣笠哲史, 黒木求, 芝口浩智, 田中俊裕, ほか
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer2007
- Author(s)
  Kinugasa, T., Kuroki, M., Shibaguchi, H., Tanaka, T., et. al.
- Organizer
  66th Ann. Meet. of Jpn Cancer Assoc.
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Amphiregulin enhances drug-resistance for pancreatic and colon cancers.2007
- Author(s)
  Fukami, T., Yagi, H., Yotsumoto, F., Oki, E., Kuroki, M., et. al.
- Organizer
  66th Ann. Meet. of Jpn Cancer Assoc.
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Amphiregulin enchances drug-resistance for pancreatic and colon cancers2007
- Author(s)
  深見達弥, 八木裕史, 四元房典, 沖英次, 黒木政秀, ほか
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Evaluation of Adv-FZ33 mediated gene transduction among anti-CEA Abs with different subclasses of mouse and human IgGs2007
- Author(s)
  田中俊裕, 趙君, 黒木求, 衣笠哲史, 芝口浩智, 加藤和則, ほか
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Evaluation of Adv-FZ33 mediated gene transduction among anti-CEA Abs with different subclasses of mouse and human IgGs2007
- Author(s)
  田中俊裕, 趙君, 黒木求, 衣笠哲史, 芝口浩智, 加藤和則, ほか
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Evaluation of Adv-FZ33 mediated gene transduction among anti-CEA Abs with different subclasses of mouse and human IgGs2007
- Author(s)
  Tanaka, T., Zhao, J., Kuroki, M., Kinugasa, T., et. al.
- Organizer
  66th Ann. Meet. of Jpn Cancer Assoc.
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Correlation between lymph node metastasis and expression of VEGF-C,-D And VEGFR-3 in primary lung adenocarcinomas2006
- Author(s)
  前川信一, 岩崎昭憲, 江夏総太郎, 衣笠哲史, 黒木求, ほか
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Expression patterns of tight junction associated proteins in colon cancer2006
- Author(s)
  衣笠哲史, 黒木求, 芝口浩智, 山田博美, ほか
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Expression patterns of tight junction associated proteins in colon cancer2006
- Author(s)
  Kinugasa, T., Kuroki, M., Shibaguchi, H., et. al.
- Organizer
  65th Ann. Meet. of Jpn Cancer Assoc.
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] IgG isotype conversion of a novel anti-carcinoembryonic antigen antibody to increase its biological activity2006
- Author(s)
  Shibaguchi, H., Kuroki, M., Kinugasa, T., Hirose, Y., Yamada, H., et. al.
- Organizer
  65th Ann. Meet. of Jpn Cancer Assoc.
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] Correlation between lymph node metastasis and expression of VEGF-C,-D And VEGFR-3 in primary lung adenocarcinomas2006
- Author(s)
  Maekawa, S., Iwasaki, A., Enatsu, S., Kinugasa, T., Kuroki, M., et. al.
- Organizer
  65th Ann. Meet. of Jpn Cancer Assoc.
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] IgG isotype conversion of a novel anti-carcinoembryonic antigen antibody to increase its biological activity2006
- Author(s)
  芝口浩智, 黒木求, 衣笠哲史, 廣瀬由美子, 山田博美, ほか
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590544
[Presentation] In vivo antitumor effect of CEA-targeted photoimmunotherapy
- Author(s)
  Shirasu N, Yamada H, Shibaguchi H, Kuroki M, Kuroki M
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26350553
[Presentation] CEAを標的とした抗腫瘍光免疫療法
- Author(s)
  白須直人，山田博美，芝口浩智，黒木　求，黒木政秀
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26350553

1. KUROKI Motomu (10131822)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
2. SHIBAGUCHI Hirotomo (60295061)

# of Collaborated Projects : 4results

# of Collaborated Products : 24results
3. TANAKA Toshihiro (00398314)

# of Collaborated Projects : 2results

# of Collaborated Products : 14results
4. 松岡雄治 (70078773)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. 山本博 (70099018)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. 荒川文子 (50212618)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. 池原征夫 (70037612)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. HAMADA Hirofumi (00189614)

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
9. KINUGASA Tetsushi (90279266)

# of Collaborated Projects : 1results

# of Collaborated Products : 12results
10. TATEISHI Kayoko (60179728)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 白日高歩 (20038863)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 白須直人 (70551422)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
13. ENDO keigo

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. ACHMAD Arifudin

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

KUROKI Masahide 黒木 政秀

Research Projects

Research Products

Co-Researchers

光感受性物質IR700を結合したヒト抗腫瘍抗体を用いる近赤外線免疫療法の確立Principal Investigator

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Study on the Usefulness of the Novel Tumor Marker MK-1 in the Diagnosis and Therapy of CancerPrincipal Investigator

Principal Investigator

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Generation and application of fully human antibodies to a new tumor-associated antigen, Ep-CAMPrincipal Investigator

Principal Investigator

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Targeted therapy of gastrointestinal cancer using human anti-CEA antibody

Principal Investigator

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Significance of a new tumor-associated antigen, MK-1, for diagnosis and therapy of cancerPrincipal Investigator

Principal Investigator

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Generation, immunologic characterization and antitumor effects of human monoclonal antibodies for carcinoembryonic antigenPrincipal Investigator

Principal Investigator

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Research Institution

A Specific Study for Clinical Application of a New Tumor-associated Antigen, MK-1,Principal Investigator

Principal Investigator

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The analysis of a new tumor-associated antigen, TSP-1, in the gene and protein expression levelsPrincipal Investigator

Principal Investigator

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Cloning of cDNA and establishment of an assay system for Mr 110,000 AgPrincipal Investigator

Principal Investigator

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粘膜上皮細胞の分化並びに癌化に伴うCEA及び関連抗原の産生動態の変化

Principal Investigator

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癌胎児性抗原(CEA)の癌特異性の本態の解明

Principal Investigator

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Preparation of site-specific antibodies by a novel immunization procedure involving induction of tolerance to cross-reacting determinants and its utilization

Principal Investigator

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[Book] Peptide Science 20092010

Author(s)

Total Pages

Publisher

Data Source

[Book] Peptide Science 2009.(K.Okamoto, ed.)(Characteristic difference of biological activity between Arg-containing and Lys-containing peptide.)2010

KUROKI Masahide 黒木政秀