Oka Junichiro 岡淳一郎

… Alternative Names

OKA Jun-Ichiro 岡淳一郎

JUN-LCHIRO Oka 岡淳一郎

岡淳一郎オカジュンイチロウ

OKA Jun-ichiro 岡淳一郎

Less

Researcher Number	40134613
Other IDs	https://orcid.org/0000-0002-1277-9977
External Links
Affiliation (Current)	2025: 東京理科大学, 薬学部薬学科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 東京理科大学, 薬学部薬学科, 教授 2012 – 2015: 東京理科大学, 薬学部, 教授 2005 – 2006: 東京理科大学, 薬学部, 教授 2000 – 2003: 東京理科大学, 薬学部, 教授 1995 – 1996: 名城大学, 薬学部, 助教授 1988: 東京大学, 薬学部, 助手 1986: Faculty of Pharmaceutical Sciences, The University of Tokyo, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Pharmacology in pharmacy / Medical pharmacy / Biological pharmacy Except Principal Investigator Psychiatric science / 応用薬理学・医療系薬学 / Biological pharmacy
Keywords	Principal Investigator GLP-1 / GLP-2 / cAMP / 認知症 / GLT-1 / IL-1β / 炎症 / BDNF / Hippocampus / 神経突起伸長 … More / 初代培養 / 経鼻投与 / うつ病 / 海馬 / カッパ(κ)受容体 / オピオイド / Oxytocin / Neuromedin U / 中枢移行性 / neurodegenerative disease / excitotoxicity / inflammation / astrocyte / microglia / CREB / アストログリア / 神経変性疾患 / 興奮毒性 / アストロサイト / ミクログリア / Learnina & memory / Concussive brain injury / Motoneuron / Neurotrophic factor / 神経生存率 / アスピリン / 神経損傷 / 頭部外傷 / 学習記憶 / 頭部外傷性意識障害 / 運動神経 / 海馬神経 / 神経栄養因子 / Neurite elongation / Primary culture / MAP kinase / Long-term potentiation(LTP) / β-Amyloid orotein / 神経細胞死 / CA1 / β-amyloid protein / GA1 / MAPキナーゼ / 長期増強現象(LTP) / βアミロイド蛋白 / ストレス / 高血圧 / 単一神経発火(ユニット) / スコポラミン / β-アミロイド蛋白 / 腹側被蓋野 / 中隔野 / ダイノルフィン / 電気生理学 / ラット / galanin / 中隔 / dynorphin … More Except Principal Investigator 痙性麻痺 / 固縮 / 情動行動 / オピオイドδ受容体 / 精神薬理学 / 抗うつ薬 / オピオイド受容体 / 内側前頭前野 / 抑うつ / 海馬 / 扁桃体 / 情動 / 消去学習 / 恐怖 / オピオイド / ERK / 抗不安薬 / PTSD / 不安 / 恐怖記憶 / Spastic paralysis / Mephenesin / Chlorpromazine / Decerebrate rigidity / バクロフェン / 痙縮 / メフェネシン / クロルプロマジン / 除脳固縮 / ノルアドレナリン / ジアゼパム / チザニジン / デオキシグルコース / 抗不安様作用 / 内側前頭前野前辺縁皮質領域 / 不安様行動 / 行動薬理学 / 精神薬理 / 行動薬理 Less

The mechanisms of the anxiolytic-like effects induced by delta opioid receptor agonists using conditioned fear test in mice
- Principal Investigator
  
  Saitoh Akiyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo University of Science
  National Center of Neurology and Psychiatry
Pharmacological and translational studies of centrally-acting peptide derivatives specialized in the delivery to the brain by the intranasal administrationPrincipal Investigator
- Principal Investigator
  
  Oka Jun-Ichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Tokyo University of Science
Investigation of the mechanisms on the emotional behaviors in mice via delta opioid receptors in prelimbic prefrontal cortex
- Principal Investigator
  
  Akiyoshi Saitoh
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  National Center of Neurology and Psychiatry
Pharmacological research on antidepressant-like effects of GLP-2 on refractory depression.Principal Investigator
- Principal Investigator
  
  OKA Jun-Ichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Science
A study of new therapeutic candidates for Alzheimer's disease utilizing microglia activation byPrincipal Investigator
- Principal Investigator
  
  OKA Jun-Ichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Science
A study of a role for GLP-1 as a newly found neurotrophic factor and its beneficial effects on brain diseasesPrincipal Investigator
- Principal Investigator
  
  OKA Jun-ichiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Science
A study of a role for inducible GLP-1 in brain disfunctionsPrincipal Investigator
- Principal Investigator
  
  JUN-LCHIRO Oka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Science
痴呆症モデル動物におけるオピオイドκ受容体を介した学習記憶改善作用機序の解明Principal Investigator
- Principal Investigator
  
  岡淳一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
オピオイドκ受容体を介した学習記憶改善作用機序の解明Principal Investigator
- Principal Investigator
  
  岡淳一郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
運動疾患モデルの作製とその応用
- Principal Investigator
  
  FUKUDA Hideomi
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Application of models of spasticity and spastic paralysis
- Principal Investigator
  
  FUKUDA Hideomi
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  The University of Tokyo

All 2019 2018 2017 2016 2015 2014 2013 2006 Other

All Journal Article Presentation Patent

[Journal Article] Selective agonists of the δ-opioid receptor, KNT-127 and SNC80, act differentially on extinction learning of contextual fear memory in mice2019
- Author(s)
  DaisukeYamada,Shoko Yanagisawa, Kazumi Yoshizawa, Shinya Yanagita, Jun-Ichiro Oka, Hiroshi Nagase, Akiyoshi Saitoh
- Journal Title
  
  NEUROPHARMACOLOGY
  
  Volume: 160 Pages: 111974-111974
- DOI
  10.1016/j.neuropharm.2019.107792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10830, KAKENHI-PROJECT-17K10286
[Journal Article] The delta opioid receptor agonist KNT-127 in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice2018
- Author(s)
  Saitoh Akiyoshi、Suzuki Satoshi、Soda Akinobu、Ohashi Masanori、Yamada Misa、Oka Jun-Ichiro、Nagase Hiroshi、Yamada Mitsuhiko
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 336 Pages: 77-84
- DOI
  10.1016/j.bbr.2017.08.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] Administration of riluzole to the basolateral amygdala facilitates fear extinction in rats2018
- Author(s)
  Sugiyama Azusa、Yamada Misa、Saitoh Akiyoshi、Oka Jun-Ichiro、Yamada Mitsuhiko
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 336 Pages: 8-14
- DOI
  10.1016/j.bbr.2017.08.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] Intranasal administration of neuromedin U derivatives containing cell-penetrating peptides and a penetration-accelerating sequence induced memory improvements in mice2018
- Author(s)
  Sasaki-Hamada Sachie、Funane Taichi、Nakao Yusuke、Sasaki Rie、Nagai Mio、Ueta Yudai、Yoshizawa Kazumi、Horiguchi Michiko、Yamashita Chikamasa、Oka Jun-Ichiro
- Journal Title
  
  Peptides.
  
  Volume: 99 Pages: 241-246
- DOI
  10.1016/j.peptides.2017.10.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07901, KAKENHI-PROJECT-15K07974, KAKENHI-PROJECT-15K14944
[Journal Article] Post-reexposure administration of riluzole attenuates the reconsolidation of conditioned fear memory in rats2018
- Author(s)
  Akagi, K., Yamada, M., Saitoh, A., Oka, JI. and Yamada, M.
- Journal Title
  
  Neuropharmacology
  
  Volume: 131 Pages: 1-10
- DOI
  10.1016/j.neuropharm.2017.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07125, KAKENHI-PROJECT-15K07974
[Journal Article] Antidepressant-like effects exerted by the intranasal administration of a glucagon-like peptide-2 derivative containing cell-penetrating peptides and a penetration-accelerating sequence in mice.2017
- Author(s)
  Sachie Sasaki-Hamada, Ryuji Nakamura, Yusuke Nakao, Toshiki Akimoto, Emi Sanai, Mio Nagai, Michiko Horiguchi, Chikamasa Yamashita, Jun-Ichiro Oka.
- Journal Title
  
  PEPTIDES
  
  Volume: 87 Pages: 64-70
- DOI
  10.1016/j.peptides.2016.11.013
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07901, KAKENHI-PROJECT-15K07974, KAKENHI-PROJECT-15K14944
[Journal Article] Neuroprotection by chotosan , a Kampo formula, against glutamate excitotoxicity involves the inhibition of GluN2B-, but not GluN2A-containing NMDA receptor-mediated responses in primary cultured cortical neurons2017
- Author(s)
  Sasaki-Hamada Sachie、Suzuki Azusa、Sanai Emi、Matsumoto Kinzo、Oka Jun-Ichiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 135 Issue: 3 Pages: 134-137
- DOI
  10.1016/j.jphs.2017.10.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] Post-reexposure administration of D-cycloserine facilitates reconsolidation of contextual conditioned fear memory in rats2017
- Author(s)
  Akiyoshi Saitoh, Kie Akagi, Jun-Ichiro Oka, Mitsuhiko Yamada
- Journal Title
  
  Journal of Neural Transmission
  
  Volume: 印刷中 Issue: 5 Pages: 583-587
- DOI
  10.1007/s00702-017-1704-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] Serotonergic and dopaminergic systems are implicated in the antidepressant-like effects of chotosan, a Kampo formula, in mice.2017
- Author(s)
  Sachie Sasaki-Hamada, Azusa Suzuki, Yudai Ueda, Kinzo Matsumoto, Jun-Ichiro Oka
- Journal Title
  
  Journal of Pharmacologic al Sciences
  
  Volume: 133 Issue: 2 Pages: 110-113
- DOI
  10.1016/j.jphs.2017.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] Administration of riluzole into the basolateral amygdala has an anxiolytic-like effect and enhances recognition memory in the rat.2017
- Author(s)
  Azusa Sugiyama, Akiyoshi Saitoh, Misa Yamada, Jun-Ichiro Oka, Mitsuhiko Yamada
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 327 Pages: 98-102
- DOI
  10.1016/j.bbr.2017.03.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] LARETH-25 and β-CD improve central transitivity and central pharmacological effect of the GLP-2 peptide2016
- Author(s)
  Yusuke Nakao,Michiko Horiguchi,Ryuji Nakamura,Sachie Sasaki-Hamada,Chihiro Ozawa,Taichi Funane,Ryo Ozawa,Jun-Ichiro Oka,Chikamasa Yamashita.
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 515(1-2) Issue: 1-2 Pages: 37-45
- DOI
  10.1016/j.ijpharm.2016.09.054
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07901, KAKENHI-PROJECT-15K07974, KAKENHI-PROJECT-15K14944
[Journal Article] The infralimbic and prelimbic medial prefrontal cortices have differential functions in the expression of anxiety-like behaviors in mice.2016
- Author(s)
  Suzuki S, Saitoh A, Ohashi M, Yamada M, Oka JI,
- Journal Title
  
  Behav Brain Res.
  
  Volume: 304 Pages: 120-124
- DOI
  10.1016/j.bbr.2016.01.044
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461730
[Journal Article] The voltage-gated sodium channel activator veratrine induces anxiogenic-like behaviors in rats.2015
- Author(s)
  Saitoh A, Makino M, Hashimoto T, Yamada M, Sugiyama A, Ohashi M, Tsukagoshi, M, Oka J, Yamada M.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 292 Pages: 316-322
- DOI
  10.1016/j.bbr.2015.06.022
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461730
[Journal Article] Induction of c-Fos immunoreactivity in the amygdala of mice expressing anxiety-like behavior after local perfusion of veratrine in the prelimbic medial prefrontal cortex.2015
- Author(s)
  Yamada M, Saitoh A, Ohashi M, Satoshi Suzuki, Oka JI, Yamada M.
- Journal Title
  
  J Neural Transm.
  
  Volume: 122 Issue: 8 Pages: 1203-1207
- DOI
  10.1007/s00702-015-1373-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461730
[Journal Article] Changes in hippocampal synaptic functions and protein expression in monosodium glutamate-treated obese mice during development of glucose intolerance2015
- Author(s)
  Sachie Sasaki-Hamada, Yuki Hojo, Hajime Koyama, Hayuma Otsuka, Jun-Ichiro Oka
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 41 Issue: 11 Pages: 1393-140
- DOI
  10.1111/ejn.12891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07974
[Journal Article] Immunohistochemical determination of the site of antidepressant-like effects of glucagon-like peptide-2 in ACTH-treated mice.2015
- Author(s)
  Sachie Sasaki-Hamada, Yoichi Yuri, Maho Hoshi, Jun-Ichiro Oka
- Journal Title
  
  Neuroscience
  
  Volume: 294 Pages: 156-165
- DOI
  10.1016/j.neuroscience.2015.03.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590126, KAKENHI-PROJECT-15K07974
[Journal Article] Riluzole in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice.2015
- Author(s)
  Ohashi M, Saitoh A, Yamada M, Oka JI, Yamada M.
- Journal Title
  
  Psychopharmacology
  
  Volume: 232 Issue: 2 Pages: 391-398
- DOI
  10.1007/s00213-014-3676-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461730
[Journal Article] Glucagon-like peptide-2-induced memory improvement and anxiolytic effects in mice.2015
- Author(s)
  Takashi Iwai, Kazushi Jin, Tomoko Ohnuki, Sachie Sasaki-Hamada, Minami Nakamura, Akiyoshi Saitoh, Azusa Sugiyama, Masaatsu Ikeda, Mitsuo Tanabe, Jun-Ichiro Oka
- Journal Title
  
  Neuropeptides
  
  Volume: 49 Pages: 7-14
- DOI
  10.1016/j.npep.2014.11.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590126
[Journal Article] Glucagon-like peptide-2 but not imipramine exhibits antidepressant-like effects in ACTH-treated mice2013
- Author(s)
  Takashi Iwai, Tomoko Ohnuki, Sachie Sasaki-Hamada, Akiyoshi Saitoh, Azusa Sugiyama, Jun-Ichiro Oka
- Journal Title
  
  Behavioral Brain Research
  
  Volume: 243 Pages: 153-157
- DOI
  10.1016/j.bbr.2013.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590126
[Journal Article] Neuronal Fos-like immunoreactivity in dexamethasone-induced hypertension of rats and effect of glucagon-like peptide-22013
- Author(s)
  Sachie Sasaki-Hamada, Kaori Ito, Jun-Ichiro Oka
- Journal Title
  
  Life Sciences
  
  Volume: 93 Issue: 23 Pages: 889-896
- DOI
  10.1016/j.lfs.2013.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590126
[Journal Article] Glucagon-like peptide-1 inhibits LPS-induced IL-1β production in cultured rat astrocytes.2006
- Author(s)
  Iwai, T, Ito, S., Tanimitsu, K., Udagawa, S., Oka, J.-I.
- Journal Title
  
  Neuroscience Research 55
  
  Pages: 352-360
- NAID
  10020614437
- Data Source
  KAKENHI-PROJECT-17590138
[Journal Article] Glucagon-like peptide-1 inhibits LPS-induced IL-lβ production in cultured rat astrocytes.2006
- Author(s)
  Iwai, T., Ito, S., Tanimitsu, K., Udagawa, S.Oka, J.-I.
- Journal Title
  
  Neuroscience Research 55-4
  
  Pages: 352-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590138
[Journal Article] Glucagon-like peptide-1 inhibits LPS-induced IL-1β production in cultured rat astrocytes.2006
- Author(s)
  Iwai, T., Ito, S., Tanimitsu, K., Udagawa, S., Oka, J.-I.
- Journal Title
  
  Neuroscience Research 55・4
  
  Pages: 352-360
- NAID
  10020614437
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590138
[Journal Article] Glucagon-like peptide-1 inhibits LPS-induced IL-1β production in cultured rat astrocytes
- Author(s)
  Iwai, T., Ito, S., Tanimitsu, K., Udagawa, S., Oka J-I.
- Journal Title
  
  Neuroscience Research (accepted)
- NAID
  10020614437
- Data Source
  KAKENHI-PROJECT-17590138
[Patent] Centrally-Acting Peptide Derivative, and Pharmaceutical Composition2017
- Inventor(s)
  山下親正、岡淳一郎、堀口道子、濱田幸恵
- Industrial Property Rights Holder
  学校法人東京理科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-02-28
- Overseas
- Data Source
  KAKENHI-PROJECT-15K07974
[Patent] 中枢作用性ペプチド誘導体及び医薬組成物2015
- Inventor(s)
  山下親正、岡淳一郎、堀口道子、濱田幸恵
- Industrial Property Rights Holder
  学校法人東京理科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-02
- Overseas
- Data Source
  KAKENHI-PROJECT-15K07974
[Patent] 中枢作用性ペプチド誘導体、点鼻剤、抗うつ剤、及び認知障害改善剤2014
- Inventor(s)
  山下親正、岡淳一郎、堀口道子、濱田幸恵
- Industrial Property Rights Holder
  学校法人東京理科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-184436
- Filing Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] KNT-127, but not SNC80, facilitates extinction learning of contextual fear memory via delta opioid receptor in mice2019
- Author(s)
  Akiyoshi Saitoh, Daisuke Yamada, Shoko Yanagisawa, Shinya Yanagita, Jun-Ichiro Oka, Hiroshi Nagase
- Organizer
  International Narcotics Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10286
[Presentation] Modulation of excitatory synaptic transmission via δ-opioid receptors in the mouse cerebral cortex2019
- Author(s)
  Daisuke Yamada, Jun-ichiro Oka, Hiroshi Nagase, Akiyoshi Saitoh
- Organizer
  The 42nd Annual Meeting of the Japan Neuroscience Society, The 62nd Annual Meeting of the Japanese for Neurochemistry
- Data Source
  KAKENHI-PROJECT-17K10286
[Presentation] Selective agonists for delta-opioid receptor, KNT-127 and SNC80, differentially act on extinction learning of contextual fear memory in mice2019
- Author(s)
  Daisuke Yamada, Shoko Yanagisawa, Shinya Yanagita, Jun-Ichiro Oka, Hiroshi Nagase, Akiyoshi Saitoh
- Organizer
  Society for Neuroscience 49th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10286
[Presentation] KNT127, a selective agonist for delta-receptors, modulates excitatory synaptic transmission in the medial prefrontal cortex2019
- Author(s)
  Daisuke Yamada, Jun-Ichiro Oka, Hiroshi Nagase, Akiyoshi Saitoh
- Organizer
  International Narcotics Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10286
[Presentation] A Selective agonist for δ-opioid receptors, KNT-127, but not SNC80, facilitates extinction learning of contextual fear memory in mice2019
- Author(s)
  Shoko Yanagisawa, Daisuke Yamada, Shinya Yanagita, Jun-ichiro Oka, Hiroshi Nagase, Akiyoshi Saitoh
- Organizer
  The 42nd Annual Meeting of the Japan Neuroscience Society, The 62nd Annual Meeting of the Japanese for Neurochemistry
- Data Source
  KAKENHI-PROJECT-17K10286
[Presentation] マウス内側前頭前野前辺縁皮質におけるオピオイドδ受容体を介した情動調節メカニズムについての検討2018
- Author(s)
  萱島修平、斎藤顕宜、早田暁伸、長瀬博、吉澤一巳、岡淳一郎、山田光彦
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用ペプチド誘導体の中枢作用：基礎研究からTRへ2018
- Author(s)
  岡淳一郎、濱田幸恵、恒岡弥生、堀口道子、秋田智后、山下親正
- Organizer
  トランスレーショナルリサーチ(TR)センター第8回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 古い文脈的恐怖記憶に対するリルゾールの効果2018
- Author(s)
  赤木希衣、山田美佐、岡淳一郎、山田光彦
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 幼若期発症1型糖尿病ラットにおける学習記憶障害に対するGLP-2の作用2018
- Author(s)
  藤原歩夢、濱田幸恵、岩井孝志、岡淳一郎
- Organizer
  トランスレーショナルリサーチ(TR)センター第8回シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] ネオエキヌリン Aの学習記憶改善作用における作用メカニズムの探索2018
- Author(s)
  佐藤匠、濱田幸恵、紙透伸治、倉持幸司、岡淳一郎
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] Glucagon-like peptide-2は海馬神経細胞のERK1/2活性化を介してLPS誘発学習機能障害を改善する2017
- Author(s)
  三島零、岩井孝志、中村みなみ、神和司、佐原郁乃、永井悠貴、渡辺俊、岡淳一郎、田辺光
- Organizer
  第19回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 認知症モデルマウスにおけるoxytocinの学習・記憶改善作用2017
- Author(s)
  植田雄大、濱田幸恵、秋田智后、山下親正、岡淳一郎
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 内側前頭前野前辺縁皮質でオピオイドδ受容体作動薬KNT-127はマウスのベラトリン誘発性不安様行動を減弱する．2017
- Author(s)
  137.斎藤顕宜、鈴木聡史、大橋正誠、早田暁伸、山田美佐、岡淳一郎、長瀬博、山田光彦
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26461730
[Presentation] 高グルコース条件下における神経興奮毒性メカニズムの検討2017
- Author(s)
  佐内恵美、濱田幸恵、恒岡弥生、岡淳一郎
- Organizer
  トランスレーショナルリサーチ(TR)センター第7回シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] モデル動物を用いたうつ病バイオマーカーの探索とGLP-2誘導体の作用について2017
- Author(s)
  小梶安椰、濱田幸恵、秋田智后、Douglas Osei-Hyiaman、大橋由明、山下親正、岡淳一郎
- Organizer
  第1回下総薬理学研究会
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 認知・情動行動における神経ペプチドの機能解明とペプチド医薬品の創出2017
- Author(s)
  岡淳一郎
- Organizer
  脳学際第1回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] モデル動物を用いたうつ病バイオマーカーの定量とGLP-2誘導体の影響2017
- Author(s)
  小梶安椰、濱田幸恵、秋田智后、Douglas Osei-Hyiaman、大橋由明、山下親正、岡淳一郎
- Organizer
  脳学際第1回シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] Glucagon-like peptide-2 rescues memory deficits and neuropathological changes in a mouse model of intracerebroventricularly administered streptozotocin-induced dementia2017
- Author(s)
  Sachie Sasaki-Hamada, Masaatsu Ikeda, Jun-Ichiro Oka
- Organizer
  第40回日本神経科学大会 (Neuroscience 2015)
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] リルゾールはラットの恐怖記憶再固定化を阻害する2017
- Author(s)
  赤木希衣、山田美佐、斎藤顕宜、岡淳一郎、山田光彦
- Organizer
  第19回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 恐怖記憶の消去と再固定化を制御する新規薬物療法の開発2017
- Author(s)
  山田光彦、赤木希衣、山田美佐、川島義高、斎藤顕宜、岡淳一郎
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 中枢投与によるGlucagon-like peptide-2の降圧作用：高血圧自然発症モデルラットとWistar-Kyotoラットでの比較。2017
- Author(s)
  濱田幸恵、成澤孝二、中村龍治、石橋仁、岡淳一郎
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松(静岡)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 認知症モデルマウスにおけるoxytocinの学習・記憶改善作用の検討2017
- Author(s)
  植田雄大、濱田幸恵、山下親正、岡淳一郎
- Organizer
  第1回下総薬理学研究会
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 幼若期発症１型糖尿病に伴う認知情動障害とその治療戦略2017
- Author(s)
  岡淳一郎、濱田幸恵、恒岡弥生、岩井孝志
- Organizer
  第19回応用薬理シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用GLP-2誘導体のペプチド性抗うつ薬としての可能性2016
- Author(s)
  岡淳一郎、濱田幸恵、堀口道子、中村龍治、中尾優介、山下親正
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜）
- Year and Date
  2016-03-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用GLP-2誘導体の開発と抗うつ様作用。2016
- Author(s)
  岡淳一郎、濱田幸恵、堀口道子、山下親正
- Organizer
  第3回日本医科大学・東京理科大学合同シンポジウム
- Place of Presentation
  日本医科大学橘桜会館 (東京)
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用GLP-2誘導体の中枢薬理作用2016
- Author(s)
  中村龍治、濱田幸恵、堀口道子、恒岡弥生、中尾優介、山下親正、岡淳一郎
- Organizer
  トランスレーショナルリサーチ(TR)センター第3回シンポジウム
- Place of Presentation
  東京理科大学葛飾キャンパス図書館大ホール (東京都葛飾区)
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用neuromedin U誘導体の学習記憶改善作用。2016
- Author(s)
  舟根太地、濱田幸恵、堀口道子、恒岡弥生、中尾優介、佐々木梨衣、山下親正、岡淳一郎
- Organizer
  トランスレーショナルリサーチ(TR)センター第5回シンポジウム
- Place of Presentation
  東京理科大学神楽坂キャンパス冨士見校舎 (東京)
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 高グルコース条件下における神経細胞障害メカニズムの検討。2016
- Author(s)
  佐内恵美、濱田幸恵、恒岡弥生、岡淳一郎
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学山上会館（東京)
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] エキソソーム様小胞封入GLP-2の経鼻投与による抗うつ様作用。2016
- Author(s)
  秋元俊希、濱田幸恵、伊豫田拓也、梅澤雅和、岡淳一郎
- Organizer
  第135回日本薬理学会関東部会
- Place of Presentation
  アクトシティ浜松研修交流センター(静岡)
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] マウスの不安様行動における内側前頭前野の役割を脳内微小透析法で探る．2016
- Author(s)
  119.斎藤顕宜、鈴木聡史、早田暁伸、赤木希衣、山田美佐，岡淳一郎、山田光彦
- Organizer
  第55回日本生体医工学会大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-04-26
- Data Source
  KAKENHI-PROJECT-26461730
[Presentation] ニューロメジンU経鼻投与用誘導体の学習記憶改善作用2016
- Author(s)
  舟根太地、濱田幸恵、堀口道子、中尾優介、佐々木梨衣、山下親正、岡淳一郎
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 内側前頭前野前辺縁皮質領域のオピオイドδ受容体は扁桃体へ投射しているグルタミン酸神経伝達を抑制し不安様行動を改善する．2016
- Author(s)
  121.斎藤顕宜、鈴木聡史、早田暁伸、大橋正誠、山田美佐、長瀬博、岡淳一郎、山田光彦
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  韓国ソウルCOEX
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-26461730
[Presentation] 幼若期発症1型糖尿病モデルラットにおける脳血管透過性の評価。2016
- Author(s)
  西村翼、恒岡弥生、岡淳一郎
- Organizer
  第134回日本薬理学会関東部会
- Place of Presentation
  国際医療福祉大学薬学部（大田原)
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用ペプチド製剤を用いた新規うつ病治療薬。2016
- Author(s)
  岡淳一郎、濱田幸恵、堀口道子、山下親正
- Organizer
  第49回精神神経系薬物治療研究報告会
- Place of Presentation
  千里ライフサイエンスセンター (大阪)
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 中枢作用性glucagon-like peptide-2 点鼻製剤の開発2015
- Author(s)
  濱田幸恵、堀口道子、中村龍治、中尾優介、山下親正、岡淳一郎
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  柏の葉カンファレンスセンター(千葉県柏市)
- Year and Date
  2015-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] オピオイドδ受容体はマウス内側前頭前野前辺縁皮質領域において神経活動依存的にグルタミン酸神経系を調節する．2015
- Author(s)
  早田暁伸，斎藤顕宜，鈴木聡史，山田美佐，岡淳一郎，山田光彦
- Organizer
  生体機能と創薬シンポジウム
- Place of Presentation
  日本大学薬学部
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-26461730
[Presentation] マウス内側前頭前野前辺縁皮質領域のグルタミン酸神経を介した不安様行動発現に対するオピオイドδ受容体作動薬KNT-127の影響．2015
- Author(s)
  斎藤顕宜，鈴木聡史，早田暁伸，山田美佐，岡淳一郎，山田光彦
- Organizer
  第26回マイクロダイアリシス研究会
- Place of Presentation
  お茶の水女子大学
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-26461730
[Presentation] Glucagon-like peptide-2の抗うつ様作用へのNO産生抑制の関与2015
- Author(s)
  中村友哉、濱田幸恵、恒岡弥生、岡淳一郎
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部(千葉県船橋市)
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 経鼻投与用中枢作用性ペプチド誘導体の作製と作用解析2015
- Author(s)
  岡淳一郎、濱田幸恵、堀口道子、恒岡弥生、中村龍治、中尾優介、山下親正
- Organizer
  トランスレーショナルリサーチ(TR)センター第2回シンポジウム
- Place of Presentation
  東京理科大学葛飾キャンパス図書館大ホール (東京都葛飾区)
- Year and Date
  2015-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] Streptozotocin誘発性認知症モデルマウスにおけるglucagon-like peptide-2の有用性の検討2015
- Author(s)
  池田将淳、濱田幸恵、恒岡弥生、岡淳一郎
- Organizer
  第132回日本薬理学会関東部会
- Place of Presentation
  明海大学浦安キャンパス(千葉県浦安市)
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] 中枢移行性の向上を目指した抗うつ様作用ペプチドGLP-2点鼻製剤の開発2015
- Author(s)
  中尾優介、中村龍治、堀口道子、濱田幸恵、岡淳一郎、山下親正
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎)
- Year and Date
  2015-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-15K07974
[Presentation] GLP-2経鼻投与用製剤の中枢作用2014
- Author(s)
  中村龍治、中尾優介、恒岡弥生、堀口道子、濱田幸恵、山下親正、岡淳一郎
- Organizer
  第130回日本薬理学会関東部会
- Place of Presentation
  星薬科大学百年記念館（東京都品川区)
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] Glucagon-like peptide-2の中枢移行性を目指した点鼻製剤の開発2014
- Author(s)
  中尾優介、中村龍治、堀口道子、濱田幸恵、岡淳一郎、山下親正
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学(東京都町田市)
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] GLP-2の抗うつ作用メカニズムの解明2014
- Author(s)
  星真帆、恒岡弥生、濱田幸恵、岡淳一郎
- Organizer
  第130回日本薬理学会関東部会
- Place of Presentation
  星薬科大学百年記念館（東京都品川区)
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] 高血圧自然発症ラットを用いたglucagon-like peptide 2の中枢及び末梢投与における降圧機序の解明
- Author(s)
  成澤孝二、濱田幸恵、岡淳一郎
- Organizer
  第7回先端分子薬理研究会
- Place of Presentation
  慈恵会医科大学(東京)
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] Diabetes onset influences hippocampal synaptic plasticity in streptozotocin-treated rats
- Author(s)
  Sasaki-Hamada, H. Sacai, J.-I. Oka
- Organizer
  Neuroscience 2012
- Place of Presentation
  Ernest N. Morial Convention Center (New Orleans, U.S.A.)
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] Immunohistochemical determination of the site of antidepressant-like effects of glucagon-like peptide-2
- Author(s)
  濱田幸恵、由利洋一、岡淳一郎
- Organizer
  第36回日本神経科学大会 (Neuro2013)
- Place of Presentation
  国立京都国際会館(京都）
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] evelopment of a nasal formulation for the GLP-2 delivery to the brain
- Author(s)
  Yusuke Nakao, Ryuji Nakamura, Chihiro Ozawa, Sachie Hamada, Michiko Horiguchi, Junichiro Oka, Chikamasa Yamashita
- Organizer
  th Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalent in Asian Countries
- Place of Presentation
  東京理科大学森戸記念館(東京都新宿区)
- Year and Date
  2014-09-16 – 2014-09-17
- Data Source
  KAKENHI-PROJECT-24590126
[Presentation] Dexamethasone誘発性高血圧モデルラットにおけるglucagon-like peptide-2の降圧作用
- Author(s)
  伊藤歌及里、濱田幸恵、岡淳一郎
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  昭和大学旗の台キャンパス(品川)
- Data Source
  KAKENHI-PROJECT-24590126

1. Akiyoshi Saitoh (00366832)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. HAMADA Sachie (00399320)

# of Collaborated Projects: 2 results

# of Collaborated Products: 39 results
3. FUKUDA Hideomi (50080172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ONO Hideki (00080200)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KUDO Yoshihisa (20080179)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 山田美佐 (10384182)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
7. 関口正幸 (80260339)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 山田光彦 (60240040)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
9. 山下親正 (30622188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
10. 山田大輔 (10621302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. YANAGITA Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oka Junichiro 岡 淳一郎

OKA Jun-Ichiro 岡 淳一郎

JUN-LCHIRO Oka 岡 淳一郎

岡 淳一郎 オカ ジュンイチロウ

OKA Jun-ichiro 岡 淳一郎

Research Projects

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The mechanisms of the anxiolytic-like effects induced by delta opioid receptor agonists using conditioned fear test in mice

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Pharmacological and translational studies of centrally-acting peptide derivatives specialized in the delivery to the brain by the intranasal administrationPrincipal Investigator

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Investigation of the mechanisms on the emotional behaviors in mice via delta opioid receptors in prelimbic prefrontal cortex

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Pharmacological research on antidepressant-like effects of GLP-2 on refractory depression.Principal Investigator

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A study of new therapeutic candidates for Alzheimer's disease utilizing microglia activation byPrincipal Investigator

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A study of a role for GLP-1 as a newly found neurotrophic factor and its beneficial effects on brain diseasesPrincipal Investigator

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A study of a role for inducible GLP-1 in brain disfunctionsPrincipal Investigator

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痴呆症モデル動物におけるオピオイドκ受容体を介した学習記憶改善作用機序の解明Principal Investigator

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オピオイドκ受容体を介した学習記憶改善作用機序の解明Principal Investigator

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運動疾患モデルの作製とその応用

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Application of models of spasticity and spastic paralysis

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Research Institution

[Journal Article] Selective agonists of the δ-opioid receptor, KNT-127 and SNC80, act differentially on extinction learning of contextual fear memory in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The delta opioid receptor agonist KNT-127 in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice2018

Oka Junichiro 岡淳一郎

OKA Jun-Ichiro 岡淳一郎

JUN-LCHIRO Oka 岡淳一郎

岡淳一郎オカジュンイチロウ

OKA Jun-ichiro 岡淳一郎