Yoshihiro Wakayama 若山吉弘

… Alternative Names

WAKAYAMA Yoshihiro 若山吉弘

若山ヨシ弘ワカヤマヨシヒロ

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Researcher Number	40138467
Other IDs
Affiliation (Current)	2025: 昭和大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2008 – 2010: Showa University, 医学部, 教授 2002 – 2006: 昭和大学, 医学部, 教授 2000: 昭和大, 医学部, 教授 1999 – 2000: 昭和大学, 医学部, 教授 1996 – 1997: 昭和大学, 医学部, 教授 … More 1993 – 1994: 昭和大学, 医学部, 教授 1989 – 1991: Professor of Neurology, Showa University School of Medicine, 医学部, 教授 1987 – 1988: 昭和大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Neurology / Neurology Except Principal Investigator Neurology / Neurology
Keywords	Principal Investigator RT-PCR / mRNA / dystrophin / 骨格筋 / Duchenne muscular dystrophy / myofilaments / quick freeze deep etch rotary shadow replica / regenerating muscle fiber / orthogonal array / muscle plasma membrane … More / RNA / Aquaporins / mechanism / depletion / genomic DNA / protein / Fukuyama dystrophy / Duchenne dystrophy / skeletal muscle / talin / calmodulin / aciculin / 骨格筋細胞 / イムノブロット / フリーズエッチレプリカ / 免疫電顕 / 骨格筋細胞膜 / Dystrophin / Cytoskeleton / レプリカ膜 / 細胞膜と細胞骨格 / 急速凍結ディープエッチ回転蒸着法 / 筋ジストロフィー症筋 / Distal angle / Myosin cross bridge / Orthogonal array / Freeze fracture法 / Qiuck freeze deep etch rotary shadow法 / Duchenne nuscular dystrophy / Immunohistochemistry / Immunoblot / Protein / Normal and disease / Skeletal myofiber / アクアポリン / 福山型筋ジストロフィー症生検筋 / 免疫組織化学 / アクアポリン7 / アクアポリン4 / アクアポリン3 / 正常骨格筋 / 免疫細胞組織化学 / 蛋白 / 正常と病的筋 / aquaporin 4 / PCR / orthogonal arrays / feeze fracture replica / 福山型筋ジストロフィー / Duchenne筋ジストロフィー症 / aquaporin4 / freeze etch replica / ultrastructure / binding domain / localization / β-spectrin / N-terminus / 超微構造 / 相互関係 / Freeze etch replica / Immunoelectron microscopy / Merosin / beta-dystroglycan / alpha-dystroglycan / Extracellular matrix / Muscle plasma membrane / ラミニン / 免疫組織化学染色 / ペプチド抗体 / ジストログリカン / 細胞骨格 / メロシン / βジストログリカン / αジストログリカン / 細胞外基質 / Replica / Rotary shadow / Deep etching / Quick freeze / Molecular shape / Human skeletal myofibers / replica膜 / rotary shadow / deep etch / quickーfreeje / Duchenne筋ジストロフィ-症筋 / 正常ヒト骨格筋 / レプリカ着 / 回転蒸着 / ディ-プエッチング / 急速凍結 / 分子の超微形態 / ジストロフィン / 筋細胞膜関連細胞骨格 / ヒト骨格筋 / アクアポリン1 / AQP1 Tgマウス / 治療 / 血管内皮 / 再生 / AQP1 / 臨床神経形態学 … More Except Principal Investigator molecular chaperone / gene sxpression / DNA array / microbeads / skeletal muscle / denervation / 分子シャペロン / 遺伝子発現 / DNAアレイ / マイクロビーズ / 骨格筋 / 除神経 / G-CSF / 臍帯血 / 筋幹細胞 / ゲンタマイシン / MDXマウス Less

AQP1 overexpression in the capillary endothelial cells for the enhancement of muscle regeneration and its therapeutic application to myopathiesPrincipal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
MDXマウスへのゲンタマイシン薬物治療と筋幹細胞移植併用療法の試み
- Principal Investigator
  
  SHIBUYA Seiji
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Showa University
Analysis of differentially expressed genes in denervated skeletal muscle using micro array technology
- Principal Investigator
  
  JIMI Takahiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
Search for aquaporin molecules at the plasma membrane of normal skeletal myofibers and their alterations in myopathic muscles.Principal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
Molecular analysis of the depletion of aquaporin 4 in the muscle plasma membrane of muscular dystrophies.Principal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
Ultrastractural localization of dystrophin N-terminal dinding proteins and their relation to dystrophin in normal skeletal myofiber.Principal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
Immunoelectron microscopic and freeze etch studies of muscle plasma membrane and extracelular matrix in normal and diseased skeletal myofiberPrincipal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
Observation of dystrophin molecule in huma skeletal myofibers by elctron microscopy of quick freeze, deep etch, rotary shadow replicas.Principal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University
Freeze etching electron microscopic study of muscle plasma membranes and myofilaments of human dystrophic muscles.Principal Investigator
- Principal Investigator
  
  WAKAYAMA Yoshihiro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Showa University

All 2004 2003 2002

All Journal Article

[Journal Article] Reduced expression of aquaporin 4 in human muscles with amyotrophic lateral sclerosis and other neurogenic-atrophies.2004
- Author(s)
  Jimi T, Wakayama Y, Matsuzaki Y, et al.
- Journal Title
  
  Pathol Res Pract 200(3)
  
  Pages: 203-209
- NAID
  10017395398
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Analysis of differentially expressed genes in denervated skeletal muscle2004
- Author(s)
  Jimi T, Wakayama Y, Matsuzaki Y, Unaki A, Hara H, Inoue M, Shibuya S
- Journal Title
  
  Ann Neurol 56・suppl 8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570619
[Journal Article] Analysis of differentially expressed genes in denervated skeletal muscle2004
- Author(s)
  Jimi T, Wakayama Y, Matsuzaki Y, Unaki A, Hara H, Inoue M, Shibuya S
- Journal Title
  
  Ann Neurol 56,suppl8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570619
[Journal Article] 実験的除神経筋で差異的に発現する遺伝子の検討2004
- Author(s)
  自見隆弘, 若山吉弘, 松崎洋子, 宇那木晶彦, 杼元千香, 原一, 井上昌彦, 渋谷誠二
- Journal Title
  
  臨床神経学 44・12
  
  Pages: 1071-1071
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570619
[Journal Article] Analysis of differentially expressed genes in denervated skeletal mascle.2004
- Author(s)
  Jim T, Wakayama Y, Matsuzaki Y, Unaki A, Hara H, Inoue M, Shibuya S
- Journal Title
  
  Ann Neurol 56・suppl 8
- Data Source
  KAKENHI-PROJECT-14570619
[Journal Article] Expression and localization of aquaporin 7 in normal skeletal myofiber.2004
- Author(s)
  Yoshihiro Wakayama
- Journal Title
  
  Cell Tissue Res 316(1)
  
  Pages: 123-129
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Expression and localization of aquaporin 7 in normal skeletal myofiber.2004
- Author(s)
  Wakayama Y
- Journal Title
  
  Cell Tissue Res 316(1)
  
  Pages: 123-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Altered aquaporin 4 expression in muscles of Fukuyama-type congenital muscular dystrophy.2003
- Author(s)
  Yoshihiro Wakayama
- Journal Title
  
  Virchows Arch 443(6)
  
  Pages: 761-767
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Altered aquaporin 4 expression in muscles of Fukuyama-type congenital muscular dystrophy.2003
- Author(s)
  Wakayama Y, Jimi T, Inoue M, et al.
- Journal Title
  
  Virchows Arch 443(6)
  
  Pages: 761-767
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Altered aquaporin 4 expression in muscles of Fukuyama-type congenital muscular dystrophy.2003
- Author(s)
  Wakayama Y
- Journal Title
  
  Virchows Arch 443(6)
  
  Pages: 761-767
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Expression of aquaporin 3 and its localization in normal skeletal myofibres.2002
- Author(s)
  Wakayama Y
- Journal Title
  
  Histochem J 34(6-7)
  
  Pages: 331-337
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Expression of aquaporin 3 and its localization in normal skeletal myofibres.2002
- Author(s)
  Yoshihiro Wakayama
- Journal Title
  
  Histochem J 34(6-7)
  
  Pages: 331-337
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570620
[Journal Article] Expression of aquaporin 3 and its localization in normal skeletal myofibres.2002
- Author(s)
  Wakayama Y, Jimi T, Inoue M, et al.
- Journal Title
  
  Histochem J 34(6-7)
  
  Pages: 331-337
- Data Source
  KAKENHI-PROJECT-14570620

1. SHIBUYA Seiji (80167444)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. JIMI Takahiro (30196654)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. INOUE Masahiko (50286770)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. SAITO Susumu (90097725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ARATA Satoru (20159502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HARA Hajima (30241029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Yoshihiro Wakayama 若山 吉弘

WAKAYAMA Yoshihiro 若山 吉弘

若山 ヨシ弘 ワカヤマ ヨシヒロ

Research Projects

Research Products

Co-Researchers

AQP1 overexpression in the capillary endothelial cells for the enhancement of muscle regeneration and its therapeutic application to myopathiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MDXマウスへのゲンタマイシン薬物治療と筋幹細胞移植併用療法の試み

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of differentially expressed genes in denervated skeletal muscle using micro array technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for aquaporin molecules at the plasma membrane of normal skeletal myofibers and their alterations in myopathic muscles.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of the depletion of aquaporin 4 in the muscle plasma membrane of muscular dystrophies.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultrastractural localization of dystrophin N-terminal dinding proteins and their relation to dystrophin in normal skeletal myofiber.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunoelectron microscopic and freeze etch studies of muscle plasma membrane and extracelular matrix in normal and diseased skeletal myofiberPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Observation of dystrophin molecule in huma skeletal myofibers by elctron microscopy of quick freeze, deep etch, rotary shadow replicas.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Freeze etching electron microscopic study of muscle plasma membranes and myofilaments of human dystrophic muscles.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Reduced expression of aquaporin 4 in human muscles with amyotrophic lateral sclerosis and other neurogenic-atrophies.2004

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Analysis of differentially expressed genes in denervated skeletal muscle2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Analysis of differentially expressed genes in denervated skeletal muscle2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 実験的除神経筋で差異的に発現する遺伝子の検討2004

Author(s)

Journal Title

Description

Data Source

Yoshihiro Wakayama 若山吉弘

WAKAYAMA Yoshihiro 若山吉弘

若山ヨシ弘ワカヤマヨシヒロ