MAKINO Kimiko 牧野公子

Researcher Number	40147509
Other IDs
Affiliation *help	2016 – 2018 : 東京理科大学, 薬学部薬学科, 教授 2013 – 2015 : 東京理科大学, 薬学部, 教授 2002 – 2008 : 東京理科大学, 薬学部, 教授 2003 : Faculty of Pharmaceutical Sciences, Tokyo University of Science, Full Professor, 薬学部・製薬学科, 教授 2001 : Faculty of Pharmaceutical Sciences, Tokyo University of Science, Associate.Professor, 薬学部・製薬学科, 助教授 … More
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Biomedical engineering/Biological material science Except Principal Investigator Physical pharmacy / Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biological material science / 医薬分子機能学
Keywords	Principal Investigator PLGA / DDS / マイクロカプセル / 刺激応答性 / 相転移 / Microsphere / 薬物デバイス / ハイドロゲル / 肺結核 / ポリエチレングリコール … More Except Principal Investigator 表面電位 / 貧食 / 貪食 / DDS / マクロファージ / Nーアセチルニュ-ラミン酸 / 結核 / 多形核白血球 / PLGA / ラテックス / phagocytosis / 糖タンパク質 / tuberculosis / シアル酸 / antigen / 肺胞マクロファージ / 慢性閉塞性肺疾患 / 糖鎖 / 結核菌 / 抗原 / NR8383細胞株 / シアリダーゼ / 薬物送達システム / ガン細胞 / アポトーシス / PLGA微粒子製剤 / 表面親水度 / ファゴソーム / 結核治療 / 肺がん / レクチン / anti-tuberculosis agent / ガレクチン / グルクロン酸 / 細胞表層抗原 / 微粒子製剤 / ポリ乳酸グリコール酸共重合体(PLGA) / 細胞表層分子 / COPD / アスパラギン結合型糖鎖 / apoptosis / tuberculosis therapy / ドラッグデリバリーシステム / リファンピシン / macrophage / galactose / 単糖類結合ラテックス粒子 / 経肺投与 / 電気泳動 / alveolar macrophage / 抗結核薬 / sialic acid / pulmonary delivery / sialidase / lectin / 柔らかい粒子 / 薬物送達システム(DDS) / cell surface molecule / ガラクトース / 経気管投与 / モルモット多形核白血球 Less

Biomimetic DDS for overcoming intractable lung diseases by activation of macrophage functions
- Principal Investigator
  
  TERADA Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
Pulmonary delivery of nanocomposite particles for the treatment oflung carcinomaPrincipal Investigator
- Principal Investigator
  
  MAKINO Kimiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
Pulmonary delivery of microspheres loaded with antituberculosis agents to alveolar macrophages for development of antituberculosis therapy
- Principal Investigator
  
  TERADA Hiroshi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
Use of microsphere technology for targeting to Mycobacterium tuberculosis-infected alveolar macrophagesPrincipal Investigator
- Principal Investigator
  
  MAKINO Kimiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
アポトーシス細胞表層抗原とマクロファージによる認識・排除機構
- Principal Investigator
  
  IKEKITA Masahiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Science University of Tokyo
Preparation ofmicrocapsule surfaces responding to both of pH and temperaturePrincipal Investigator
- Principal Investigator
  
  KUMIKO Makino
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
電気泳動法によるガン細胞表面の物理化学的研究
- Principal Investigator
  
  大島広行
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo University of Science
pHとイオン強度に応答したハイドロゲルマイクロカプセル膜の構造変化Principal Investigator
- Principal Investigator
  
  牧野公子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
中性リン脂質リポソーム表面のリン脂質分子の会合状態に与える外部環境の効果Principal Investigator
- Principal Investigator
  
  牧野公子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
食細胞による高分子微小球の貧食に及ぼす諸因子の研究
- Principal Investigator
  
  近藤保
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Science
食細胞による高分子微小球の貪食に及ぼす諸因子の研究
- Principal Investigator
  
  近藤保
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Science
食細胞による高分子微小球の貧食に及ぼす諸因子の研究
- Principal Investigator
  
  近藤保
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Science

All 2016 2015 2014 2013 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] Inhalation therapy for pulmonary tuberculosis, Targeted Drug Delivery2015
- Author(s)
  Keiji Hirota, Keishiro Tomoda, Kimiko Makino, Hiroshi Terada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25282146
[Book] 注射剤・経口製剤に代わる新しい薬剤投与デバイスの開発2014
- Author(s)
  牧野公子、廣田慶司、寺田弘
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-25282146
[Book] 物理化学テキスト葛谷昌之編集第8章廣川書店2008
- Author(s)
  牧野公子
- Publisher
  物理平衡
- Data Source
  KAKENHI-PROJECT-19300177
[Book] 物理化学テキスト葛谷昌之編集2008
- Author(s)
  牧野公子
- Total Pages
  241
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-19300177
[Book] 機能性化粧品の開発III 鈴木正人監修第4編第4章CMCシーエムシー2007
- Author(s)
  牧野公子
- Publisher
  マイクロカプセル
- Data Source
  KAKENHI-PROJECT-19300177
[Book] 機能性化粧品の開発III 鈴木正人監修中、第4章「マイクロカプセル」2007
- Author(s)
  牧野公子
- Total Pages
  6
- Publisher
  CMCシーエムシー
- Data Source
  KAKENHI-PROJECT-19300177
[Book] 抗菌・抗カビの最新技術とDDSの実際2005
- Author(s)
  牧野公子, 杣源一郎, 寺田弘
- Total Pages
  283
- Publisher
  エヌ・ティー・エス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Book] 抗菌・抗カビの最新技術とDDSの実際2005
- Author(s)
  牧野公子, 杣源一郎, 寺田弘
- Total Pages
  283
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-15300170
[Book] Recent advances in antibacterial and antifungal treatment an DDS2005
- Author(s)
  K.Makino, G.Soma, H.Terad
- Total Pages
  283
- Publisher
  N.T.S
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Polyphosphoester-based Paclitaxel Complexes: Biological Evaluation2016
- Author(s)
  Keiji Hirota, Tatyana Hristova, Violeta Mitova, Tomoyuki Koda, Masahiro Fushimi, Mika Kuniya, Kimiko Makino, Hiroshi Terada, Rumyana Cherkezova, Shin-Ichi Yusa, Neli Koseva and Kolio Troev
- Journal Title
  
  Anticancer Res.
  
  Volume : 36 Pages : 1613-1620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282146
[Journal Article] A Novel Mechanism Underlying the Basic Defensive Response of Macrophages against Mycobacterium Infection.2014
- Author(s)
  Iyoda T, Takada M, Fukatsu Y, Kumokoshi S, Fujisawa T, Shimada T, Shimokawa N, Matsunaga T, Makino K, Doi N, Terada H, Fukai F
- Journal Title
  
  Journal of Immunology
  
  Volume : 192（9） Pages : 4254-4262
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282146
[Journal Article] Surfactant free preparation of PLGA nanoparticles: The combination of antisolvent diffusion with preferential salvation2014
- Author(s)
  Keishiro Tomoda, Natsumi Yabuki, Hiroshi Terada, Kimiko Makino
- Journal Title
  
  Colloids and Surfaces A: Physicochemical and Engineering Aspects
  
  Volume : 457 Pages : 88-93
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282146
[Journal Article] Distribution and deposition of respirable PLGA microspheres in lung alveoli2013
- Author(s)
  Keiji Hirota, Tadafumi Kawamoto, Takehisa Nakajima, Kimiko Makino, Hiroshi Terada
- Journal Title
  
  COLLOIDS AND SURFACES B-BIOINTERFACES
  
  Volume : 105 Pages : 92-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282146
[Journal Article] Study of types and mixture ratio of organic solvent used to dissolve polymers for preparation of drug-containing PLGA microspheres2009
- Author(s)
  Fuminori Ito, Hiroyuki Fujimori, Hiroyuki Honnami, Hiroyoshi Kawakami, Kiyoshi Kanamura and Kimiko Makino
- Journal Title
  
  European Polymer Journal 45
  
  Pages : 658-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Electrophoretic mobility of colloidal gold particles in electrolyte solutions2009
- Author(s)
  agar M. Agnihotri, Hiroyuki Ohshima, Hiroshi Terada, Keishiro Tomoda, Kimiko Makino
- Journal Title
  
  Langmuir, accepted 26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Biodistribution of colloidal gold nanoparticles after intravenous administration : Effect of particle size Colloids and Surfaces B2008
- Author(s)
  Ganeshchandra Sonavane, Keishiro Tomoda, and Kimiko Makino
- Journal Title
  
  Biointerfaces 66
  
  Pages : 274-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Preparation and properties of PLGA microspheres containing hydrophilic drugs by the SPG (shirasu porous glass) membrane emulsification technique2008
- Author(s)
  Fuminori Ito, Hiroyuki Honnami, Hiroyoshi Kawakami, Kiyoshi Kanamura and Kimiko Makino
- Journal Title
  
  Colloids and Surfaces B ; Biointerfaces 67
  
  Pages : 20-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] In vitro permeation of gold nanoparticles through rat skin and intestine : Effect of particle size2008
- Author(s)
  Ganeshchandra Sonavane, Keishiro Tomoda, Akira Sano, Hiroyuki Ohshima, Hiroshi Terada and Kimiko Makino
- Journal Title
  
  Colloids and Surfaces B ; Biointerfaces 65
  
  Pages : 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Effect of polyethylene glycol on preparation of rifampicin-loaded PLGA microspheres with membrane emulsification technique2008
- Author(s)
  Fuminori Ito, Hiroyuki Fujimori, Hiroyuki Honnami, Hiroyoshi Kawakami, Kiyoshi Kanamura and Kimiko Makino
- Journal Title
  
  Colloids and Surfaces B ; Biointerfaces 66
  
  Pages : 5-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Preparation and properties of inhalable nanocomposite particles : Effects of the size, weight ratio of the primary nanoparticles in nanocomposite particles and temperature at a spray-dryer inlet upon properties of nanocomposite particles2008
- Author(s)
  Keishiro Tomoda, Takumi Ohkoshi, Takehisa Nakajima, Kimiko Makino
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 64
  
  Pages : 70-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Exact determination of phagocytic activity of alveolar macrophages toward polymer microspheres by elimination of those attached to the macrophage membrane2008
- Author(s)
  Taizo Hasegawa, Kanako Iijima, Keiji Hirota, Takehisa Nakajima, Kimiko Makino, and Hiroshi Terada
- Journal Title
  
  Colloids and Surfaces B ; Biointerfaces 63
  
  Pages : 209-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Junichi Kitagawa, Masanori Nasu, Hayato Okumura, Akihiko Shibata, Kimiko Makino, Hiroshi Terada, Shigeji Matsumoto2008
- Author(s)
  Junichi Kitagawa, Masanori Nasu, Hayato Okumura, Akihiko Shibata, Kimiko Makino, Hiroshi Terada, Shigeji Matsumoto
- Journal Title
  
  J. Radiat. Res. 49
  
  Pages : 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Peparation and properties of inhalable nanocomposite particles : effects of tempearature at a spray-dryer inlet upon the properties of particles2008
- Author(s)
  Keishiro Tomoda, Takehisa Nakajima, Satoru Ohgoshi, Yusaku Kawai and Kimiko Makino
- Journal Title
  
  Colloids and Surfaces B ; Biointerfaces 61
  
  Pages : 138-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Factors affecting the loading efficiency of water-soluble drugs in PLGA microspheres2008
- Author(s)
  Fuminori Ito, Hiroyuki Fujimori, and Kimiko Makino
- Journal Title
  
  Colloids and Surfaces B ; Biointerfaces 61
  
  Pages : 25-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Preparation and properties of inhalable nanocomposite particles.2008
- Author(s)
  K. Tomoda, K. Makino, et. al.
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces 61(2)
  
  Pages : 138-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Phagocytic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis agent2007
- Author(s)
  Taizo Hasegawa, Keiji Hirota, Keishiro Tomoda, Fuminori Ito, Hiroyuki Inagawa, Chie Kochi, Gen-Ichiro Soma, Kimiko Makino and Hiroshi Terada
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 60
  
  Pages : 221-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] I-Shaped Microchannel Array Chip for Parallel Electrophoretic Analyses2007
- Author(s)
  Akira Inoue, Toshiyuki Ito, Kimiko Makino, Kazuo Hosokawa, and Mizuo Maeda
- Journal Title
  
  Anal. Chem. 79
  
  Pages : 2168-2173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages2007
- Author(s)
  Keiji Hirota, Taizo Hasegawa, Hideyuki Hinata, Fuminori Ito, Hiroyuki Inagawa, Chie Kochi, Gen-Ichiro Soma, Kimiko Makino and Hiroshi Terada
- Journal Title
  
  Journal of Controlled Release 119
  
  Pages : 69-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Effects of lung surfactants on rifampicin release rate from monodisperse2007
- Author(s)
  K. Tomoda and K. Makino
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces 55(1)
  
  Pages : 115-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Phagocytotic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis---.2007
- Author(s)
  T. Hasegawa, G. Soma, K. Makino, H. Terada,
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces 60(2)
  
  Pages : 221-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Selective delivery of rifampicin incorporated into pol (DL-lactic-co-glycolic) acid microspheres after phagocytosis.2006
- Author(s)
  A.Yoshida, H.Inagawa, K.Makino, H.Terada, et al.
- Journal Title
  
  Microbes and Infection 8
  
  Pages : 2484-2491
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Selective delivery of rifampicin incorporated into poly (DL-lactic-co-glycolic)acid microspheres.2006
- Author(s)
  A.Yoshida, H.Inagawa, K.Makino, H.Terada et al.
- Journal Title
  
  Microbes and Infection 8
  
  Pages : 2484-2491
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Selective delivery of rifampicin incorporated into poly (DL-lactic-co-glycolic) acid microspheres after phago.2006
- Author(s)
  A.Yoshida, H.Inagawa, K.Makino, H.Terada, et al.
- Journal Title
  
  Microbes and Infection 8
  
  Pages : 2484-2491
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Innate-immune Therapy for Lung Carcinoma Based on Tissue-macrophage Activation with Lipopolysaccharide.2005
- Author(s)
  M.Hino, C.Kouchi, T.Nishizawa, H.Inagawa, H.Hori, K.Makino, H.Terada, G.Soma
- Journal Title
  
  Anticancer Res. 25
  
  Pages : 3747-3754
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Innate-immune therapy for lung carcinoma based on tissue-macrophage activation with lipopolysaccharide.2005
- Author(s)
  M.Hino, C.Kouchi, T.Nishizawa, K.Makino, H.Terada, et al.
- Journal Title
  
  Anticancer Researh 25
  
  Pages : 3747-3754
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Establishment of In Vitro Model using NR8383 Cells and Mycobacterium Bovis Calmette-Guerin that Mimes a Chronic Infection of Mycobaceterium Tuberculosis.2005
- Author(s)
  M.Hino, Kohchi, T.Nishizawa, H.Inagawa, H.Hori, K.Makino, H.Terada, G.Soma
- Journal Title
  
  In Vivo. 19
  
  Pages : 821-830
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Establishment of in vitro model using NR8383 cells and mycobacterium Bovis calmette-guerin.2005
- Author(s)
  M.Hino, Kohchi, T.Nishizawa, K.Makino, H.Terada et al.
- Journal Title
  
  In Vivo 19
  
  Pages : 821-830
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Innate-immune therapy for lung carcinoma based on tissue- macrophage activation with lipopolysaccharide.2005
- Author(s)
  M.Hino, T.Nishizawa, K.Makino, H.Terada et al.
- Journal Title
  
  Anticancer Research 25
  
  Pages : 3747-3754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Establishment of in vitro model using NR8383 cells and mycobacterium Bovis calmette-guerin.2005
- Author(s)
  M.Hino, T.Nishizawa, K.Makino, H.Terada et al.
- Journal Title
  
  In Vivo 19
  
  Pages : 821-830
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Efficient intracellular delivery of rifampicin to alveolar macrophages using rifampicin-loaded PLGA microspheres.2004
- Author(s)
  K.Makino, T.Nakajima, M.Shikamura, H.Terada et al.
- Journal Title
  
  Colloids Surfaces B : Biointerfaces 36
  
  Pages : 35-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Efficient intracellular delivery of rifampicin to alveolar macrophages using rifampicin-loaded PLGA microspheres.2004
- Author(s)
  K.Makino, T.Nakajima, M.Shikamura, F.Itoh, S.Ando, H.Terada
- Journal Title
  
  Colloids Surfaces B : Biointerfaces 36
  
  Pages : 35-42
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Efficient intracellular delivery of rifampicin to alveolar macrophages using rifampicin-loaded PLGA microspheres.2004
- Author(s)
  K.Makino, T.Nakaj ima, M.Shikamura, H.Terada et al.
- Journal Title
  
  Colloids Surfaces B : Biointerfaces 36
  
  Pages : 35-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Utilization of macrophages in anticancer therapy : the macrophage network theory.2004
- Author(s)
  C.Kochi, H.Inagawa, A.Yoshida, H.Terada, M.Makino, G.Soma
- Journal Title
  
  Anticancer Res. 24
  
  Pages : 3311-3320
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Effects of liposomal phosphatidyl serine on phagocytic uptake of liposomes by macrophage-like HL-6ORG cells.2003
- Author(s)
  K.Makino, T.Yoshioka, H.Ohshima, H.Terada et al.
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 29
  
  Pages : 277-284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Effects of liposomal phosphatidylserine on phagocytic uptake of liposomes by macrophage-like HL-60RG cells.2003
- Author(s)
  K.Makino, T.Yoshioka, H.Ohshima, H.Terada et al.
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 29
  
  Pages : 277-284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Presentation] マクロファージ活性化因子GcMAFを用いた肺がん治療メカニズムの解析2016
- Author(s)
  大野智也、廣田慶司、竹内一成、宇都義治、堀均、牧野公子、寺田弘
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] マウス用新規経肺投与デバイスの開発と評価2016
- Author(s)
  木村永実理、竹内一成、寺田弘、牧野公子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] Lipid A類縁体とアルキル化剤との併用による効果的な肺がん治療2016
- Author(s)
  國谷美果、竹内一成、寺田弘、牧野公子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] マクロファージ活性化剤の経肺投与と化学療法剤の併用による効果的な肺がん治療法2015
- Author(s)
  伏見雅裕、國谷美果、鈴木里歩、廣田慶司、竹内一成、牧野公子、寺田弘
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] エラスターゼ誘導性肺気腫モデルマウスにおけるレチノイン酸の炎症抑制効果2015
- Author(s)
  小澤祐平、松原理恵、竹内一成、堀口道子、山下親正、牧野公子、首藤紘一、寺田弘
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] Effecive antitumor activity of inhaled Lipid A nanalog combined with chemotherapeutic agent2014
- Author(s)
  伏見雅裕、廣田慶司、竹内一成、牧野公子、寺田弘
- Organizer
  Fifth Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalant in Asian Countries
- Place of Presentation
  東京理科大学森戸記念館
- Year and Date
  2014-09-16
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] Determination of Live Mycobacterium tuberculosis by Quantitative PCR2014
- Author(s)
  小棚木彩乃、廣田慶司、竹内一成、牧野公子、寺田弘
- Organizer
  Fifth Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalant in Asian Countries
- Place of Presentation
  東京理科大学森戸記念館
- Year and Date
  2014-09-16
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] 薬物内包ナノ粒子とイオントフォレシスを組み合わせた経皮吸収製剤の開発2014
- Author(s)
  武田洋平、竹内一成、寺田弘、牧野公子
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] ホウ素中性子捕捉療法（BNCT）を利用した肺がん治療用経肺投与製剤の開発2014
- Author(s)
  岩瀧貴紀、竹内一成、中島武尚、寺田弘、牧野公子
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] The effect of Am80 acid on inflammation in elastase-induced emphemsema2014
- Author(s)
  小澤祐平、廣田慶司、竹内一成、牧野公子、堀口道子、山下親正、寺田弘
- Organizer
  Fifth Indo-Japanese International Joint Symposium on Overcoming Intractable Infectious Diseases Prevalant in Asian Countries
- Place of Presentation
  東京理科大学森戸記念館
- Year and Date
  2014-09-16
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] Inhalable nano composite particles for treatment of lung cancer2008
- Author(s)
  Kimiko Makino
- Organizer
  8^<th> CRS-Symposium at B. V. Patel center, Ahmedabad
- Place of Presentation
  India
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Pulmonary Drug Delivery System : Inhalable nano composite particles for the treatment of lung cancer2008
- Author(s)
  Kimiko Makino
- Organizer
  11^<th> Canadian Society for Pharmaceutical Sciences Annual Meeting
- Place of Presentation
  The Banff Center, Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Nanomedicine : Biodistribution of Gold Nano Colloids : Nano composite Particles for the Treatment of Lung Carcinoma2008
- Author(s)
  Kimiko Makino
- Organizer
  The 17^<th> Nissin Engineering Particle Technology International Seminar(NEPTIS-17) on Interactions between Biomaterials and Solids -Fundamentals and application from DDS to environmental Problems- Nara Hotel
- Place of Presentation
  Nara, Japan
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Pulmonary Drug Delivery System for Efficient Treatment of Tuberculosis2008
- Author(s)
  Kimiko Makino
- Organizer
  The Ehrlich II conference, 2nd World Conference on Magic Bullets
- Place of Presentation
  Nurnberg, Germany
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Pulmonary Drug Delivery System : Inhalable nano composite particles for the treatment of lung cancer.2008
- Author(s)
  Kimiko Makino
- Organizer
  11^<th> Canadian Society for Pharmaceutical Sciences Annual Meeting
- Place of Presentation
  The Banff Center, Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Inhalable nano-composite particles for treatment of lung cancer2008
- Author(s)
  K. Makino
- Organizer
  8th CRS-Symposium at B. V. Patel center
- Place of Presentation
  Ahmedabad、India
- Year and Date
  2008-02-26
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] 結核治療を目的とした経肺吸収製剤第23回日本DDS学会2007
- Author(s)
  牧野公子
- Organizer
  シンポジウム3ホテル日航熊本
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Pulmonary drug delivery system for efficient treatment of tuberculosis2007
- Author(s)
  Kimiko Makino
- Organizer
  1^<st> Indo-Japanese International Joint Symposiumu on Overcoming Intractable Infecctious Diseases Prevalent in Asian Countries
- Place of Presentation
  Morito Hall, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] 結核治療に応用可能な気道内DDS治療について2007
- Author(s)
  牧野公子
- Organizer
  第30回日本呼吸器内視鏡学会学術集会ワ-クショップ3気管支からの内科的治療
- Place of Presentation
  東京ドームホテル
- Year and Date
  2007-06-08
- Data Source
  KAKENHI-PROJECT-19300177
[Presentation] Anti-tubercular effect of rifampicin-PLGA microspheres insufflated into rat lung infected with BCG
- Author(s)
  Hirota Keiji, Nakajima Takehisa, Tomoda Keishiro, Makino Kimiko ,Terada Hiroshi
- Organizer
  Inhaled Therapies for TB: Second Meeting--Tokyo2013
- Place of Presentation
  Tokyo, Morito Hall, TUS
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] Pulmonary delivery system for the treatment of TB and lung carcinoma. ,
- Author(s)
  Keishiro Tomoda, Takehisa Nakajima, Keiji Hirota, Hiroshi Terada , Kimiko Makino
- Organizer
  Inhalation Asia 2013
- Place of Presentation
  The University of Hong Kong
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] A novel device for pulmonary administration of dry powders to small animals based on the Venturi effect
- Author(s)
  Keiji Hirota, Yutaka Hirai, Takehisa Nakajima, Kimiko Makino, Hiroshi Terada
- Organizer
  Inhaled Therapies for TB: Second Meeting--Tokyo2013
- Place of Presentation
  Tokyo, Morito Hall, TUS
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] The behavior of PLGA microspheres containing rifampicin in alveolar macrophages
- Author(s)
  Onoshita, T., Fujiwara, N., Haga, M., Nakajima, T., Tomoda, K., Hirota, K., Terada, H., Makino, K.
- Organizer
  Inhaled Therapies for TB: Second Meeting--Tokyo2013
- Place of Presentation
  Tokyo, Morito Hall, TUS
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] 定量PCRを用いた結核生菌数測定法の開発
- Author(s)
  小棚木彩乃、廣田慶司、牧野公子、寺田弘
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学工学部
- Data Source
  KAKENHI-PROJECT-25282146
[Presentation] 肺胞マクロファージの微粒子取り込みに対するサイズ効果
- Author(s)
  柳沼啓太、白井俊太郎、木村俊一、廣田慶司、牧野公子、寺田弘
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学工学部
- Data Source
  KAKENHI-PROJECT-25282146

1. HIROYUKI Ohshima (60176873)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
2. TERADA Hiroshi (00035544)

# of Collaborated Projects : 5results

# of Collaborated Products : 46results
3. SOMA Gen-ichiro (00158990)

# of Collaborated Projects : 4results

# of Collaborated Products : 9results
4. 近藤保 (70084415)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. 村松延弘 (10112905)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. HIROTA Keiji (50516359)

# of Collaborated Projects : 2results

# of Collaborated Products : 18results
7. IKEKITA Masahiko (70138981)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. KOJIMA Shuji (90119579)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
9. 深井文雄 (90124487)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. TAKEUCHI Issei (10734931)

# of Collaborated Projects : 1results

# of Collaborated Products : 10results
11. SHINOHARA Yasuo (60226157)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 友田敬士郎 (70516400)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
13. 伊藤史典 (10366429)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. SONAVANE Ganeshchandra (90449231)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results

MAKINO Kimiko 牧野 公子

Research Projects

Research Products

Co-Researchers

Biomimetic DDS for overcoming intractable lung diseases by activation of macrophage functions

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Pulmonary delivery of nanocomposite particles for the treatment oflung carcinomaPrincipal Investigator

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Pulmonary delivery of microspheres loaded with antituberculosis agents to alveolar macrophages for development of antituberculosis therapy

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Use of microsphere technology for targeting to Mycobacterium tuberculosis-infected alveolar macrophagesPrincipal Investigator

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アポトーシス細胞表層抗原とマクロファージによる認識・排除機構

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Preparation ofmicrocapsule surfaces responding to both of pH and temperaturePrincipal Investigator

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電気泳動法によるガン細胞表面の物理化学的研究

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pHとイオン強度に応答したハイドロゲルマイクロカプセル膜の構造変化Principal Investigator

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中性リン脂質リポソーム表面のリン脂質分子の会合状態に与える外部環境の効果Principal Investigator

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食細胞による高分子微小球の貧食に及ぼす諸因子の研究

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食細胞による高分子微小球の貪食に及ぼす諸因子の研究

Principal Investigator

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Research Institution

食細胞による高分子微小球の貧食に及ぼす諸因子の研究

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[Book] Inhalation therapy for pulmonary tuberculosis, Targeted Drug Delivery2015

Author(s)

Publisher

Data Source

[Book] 注射剤・経口製剤に代わる新しい薬剤投与デバイスの開発2014

Author(s)

Publisher

MAKINO Kimiko 牧野公子

[Book] 物理化学テキスト葛谷昌之編集2008