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MIZOKAMI Masashi  溝上 雅史

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… Alternative Names

溝上 雅史  ミゾカミ マサシ

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Researcher Number 40166038
Other IDs
Affiliation (based on the past Project Information) *help 2023 – 2024: 国立研究開発法人国立国際医療研究センター, その他部局等, ゲノム医科学プロジェクト長
2018: 国立研究開発法人国立国際医療研究センター, その他部局等, ゲノム医科学プロジェクト長
2016 – 2017: 国立研究開発法人国立国際医療研究センター, その他部局等, 肝炎免疫研究センター長
2015: 国立研究開発法人国立国際医療研究センター, その他部局等, センター長
2014: 独立行政法人国立国際医療研究センター, その他部局等, 研究センター長 … More
2012 – 2014: 独立行政法人国立国際医療研究センター, その他部局等, その他
2011 – 2012: 独立行政法人国立国際医療研究センター, 肝炎・免疫研究センター, センター長
2009 – 2010: Nagoya City University, 大学院・医学研究科, 客員教授
2007 – 2008: Nagoya City University, Graduate School of Medical Sciences, Professor
2006: 名古屋市立大学, 大学院医学研究科, 教授
2006: 名古屋市立大学, 大学院医学研究科・臨床分子情報医学, 教授
2003 – 2004: 名古屋市立大学, 大学院・医学研究科, 教授
2001: Nagoya City University, Medical School, Professor, 医学部, 助教授
2000 – 2001: 名古屋市立大学, 医学部, 教授
1998 – 1999: NAGOYA CITY UNIVERSITY,MEDICAL SCHOOL,ASSOCIATE PROFFESER, 医学部, 助教授
1997: Nagoya City University Medical School, Second Department of Medicine, Lecturer, 医学部, 講師
1994 – 1996: 名古屋市立大学, 医学部, 助手
1988 – 1990: 名古屋市立大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Basic Section 48040:Medical biochemistry-related / Virology
Except Principal Investigator
Gastroenterology / Gastroenterology / 遺伝 / 遺伝学 / Biological Sciences
Keywords
Principal Investigator
genotype / HBV / Genotype / RFLP / HGV / GBV-C / 糖鎖 / バイオマーカー / 肝がん / 肝線維化 … More / Molecular evolutionary analysis / Nucleotide mutation / Antiviral therapy / Epidemiological difference / subtype / X-C領域 / 分子進化学的解析法 / 臨床像 / 分子進化学的解析 / 遺伝子変異 / 抗ウイルス療法 / 地理的分布 / prognosis / diagnosis / distribution / 分布状況 / HBe抗原 / Genotype C / Genotype B / Genotype A / HBV genotype / 臨床的意義 / 分布 / hepatocellular carcinoma / molecular evolutionary / polymerase chair reaction / G型肝炎ウイルス / 肝炎ウイルス / 癌抑制遺伝子 / RELP / 肝細胞癌 / 分子進化 / 受容体 / 進化 / シグナル伝達 / 転写 / インターフェロンラムダ / HBV遺伝子型 / キメラマウス / 薬剤耐性 / ラミブジン / エンテカビル / B型肝炎ウイルス … More
Except Principal Investigator
B型肝炎ウイルス / Hepatocellular carcinoma / HBV / HIV / 肝がん / 遺伝子変異 / B型肝炎 / C型肝炎ウイルス / HBV genotype / Epidemiology / Microcystins / Mycotoxins / Environmental factors / Host factors / Haimen, China / 疫学 / マイクロシスチン / マイコトキシン / 生活環境要因 / 宿主要因 / 中国海門市 / 分子進化 / ジェノタイプ / 急性肝炎 / 系統樹 / キメラマウス / 遺伝子型 / HCV / 地理的分布 / genotype / 分子生物学 / 糖鎖 / 分子生物学的検討 / 系統解析 / エンベロープ / 慢性肝炎 / ワクチン / Chimeric mice / Hepatitis B Viral replication / core promoter Mutation / Hepatitis B virus (HBV) / ウイルス複製 / HBV複製 / 肝細胞癌 / コアプロモーター変異 / HBV遺伝子型 / Cytokine / Dendritic Cell / Cytotoxic T Lymphocyte / サイトカイン / 樹状細胞 / 細胞障害性Tリンパ球 / 宿上要因 / nucleotide substitution / subtype / phylogenetic tree / GB virus / hepatitis B virus / molecular evolution / hepatitis C virus / 塩基置換 / 塩素置換 / サブタイプ / GBウイルス / IFN therapy / HCV RNA level / Geographic distribution / Chronic liver disease / HCV genotype / Hepatitis C virus (HCV) / ウイルス量 / コア蛋白定量法 / PCR法 / 肝疾患 / Hepatitis B virus / AFB_1 / 感染阻止実験 / ウイルス増殖抑制試験 / 合成ペプチド / ワクチン開発 / 外被糖タンパク / AIDS / envペプチド / 結晶解析 / ウイルス増殖抑制 / 中和試験 / 分子進化学 / 合成ワクチン / AIDSウイルス / ミエロイド細胞 / 血管新生 / B型慢性肝炎 / B型急性肝炎 / SNPs / quasispecies / genotype A / HLA / 次世代シーケンサー / 慢性化 / 再活生化 / 再活性化 / コアプロモーター / recombination / 複製モデル / Vaccine / 中和活性 / ウイルス変異 / 肝癌 / 肝細胞 / 遺伝子導入 / 感染実験 / ウイルス / レプリコンシステム / リバビリン / インターフェロン / 薬剤感受性 / 肝炎ウイルス / Genotype / 肝細胞障害性 / 慢性肝疾患 / TTウイルス Less
  • Research Projects

    (21 results)
  • Research Products

    (155 results)
  • Co-Researchers

    (63 People)
  •  肝線維化糖鎖バイオマーカーの糖鎖異性化機構と分子機能の相関解明Principal Investigator

    • Principal Investigator
      溝上 雅史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      National Center for Global Health and Medicine
  •  Trend and molecular biological analysis of hepatitis B virus genotype distribution

    • Principal Investigator
      Ito Kiyoaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Aichi Medical University
  •  Investigation of anti-angiogenesis therapy against hepatocellular carcinoma targeting liver-infiltrating myeloid cells.

    • Principal Investigator
      Kanto Tatsuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Center for Global Health and Medicine
  •  Development of the method for the prevention of the chronicity of hepatitis B virus infection using two types of next generation sequencer

    • Principal Investigator
      ITO Kiyoaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Aichi Medical University
  •  Response and specific function of IFN-lambda3 against infectious diseasesPrincipal Investigator

    • Principal Investigator
      MIZOAKMI Masashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  Mechanism of drug resistance among HBV genotypesPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Masashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  A comprehensive study of recombinant hepatitis B virus genotype

    • Principal Investigator
      SUGAUCHI Fuminaka
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  感染性C型肝炎ウイルス粒子による肝細胞への遺伝子デリバリーシステムの構築

    • Principal Investigator
      脇田 隆字
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Infectious Diseases
  •  Influence of hepatitis B virus core promoter mutations on hepatocellular carcinoma among Japanese patients

    • Principal Investigator
      TANAKA Yasuhito
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  HCVレプリコンシステムを用いた薬剤感受性規定領域の検討

    • Principal Investigator
      加藤 孝宣
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  Clinical characteristics of hepatitis B virus genotypesPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Masashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  HBV genotype distribution in Japan and it's clinical significancePrincipal Investigator

    • Principal Investigator
      MIZOKAMI Masashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  TTウイルス感染率、genotypeの地理的分布および感染と肝疾患との関連性

    • Principal Investigator
      IINO Shiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      St. Marianna University School of Medicine
  •  Establishment and Comparison of HCV Specific CTL and Tumor-Antigen Specific CTL.

    • Principal Investigator
      OHONO Tomoyoshi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  Genotypic classification of GB virus C/Hepatitis G virus by molecular evolutionary analysis and its clinical applicationPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Masashi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      NAGOYA CITY UNIVERSITY
  •  Risk factors of hepatocellular carcinoma in Haimen, China

    • Principal Investigator
      TOKUDOME Shinkan
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  Genotypic distribution of hepatitis C virus and chronic liver diseases

    • Principal Investigator
      IINO Shiro
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      St.Marianna University, School of Medicine
  •  Elucidation of molecular evolutinary mechanisms of HIV and HCV

    • Principal Investigator
      GOJOBORI Takashi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      遺伝
    • Research Institution
      National Institute of Genetics
  •  分子進化学的手法によるC型肝炎ウイルスの遺伝子分類とその臨床応用Principal Investigator

    • Principal Investigator
      溝上 雅史
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  Risk factors of hepatocellular carcinoma in Haimen, China

    • Principal Investigator
      TOKUDOME Shinkan
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University Medical School
  •  AIDSウィルス合成ワクチンのための総合的方法論を目指した試験的研究

    • Principal Investigator
      GOJOBORI Takashi
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      遺伝学
    • Research Institution
      National Institute of Genetics

All 2018 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Patent

  • [Book] 第29回 犬山シンポジウム記録集 B型急性肝炎および慢性肝疾患におけるHBVゲノタイプAの頻度と感染経路の検討2013

    • Author(s)
      鈴木一幸、滝川康裕、遠藤龍人、宮坂昭生、宮本康弘、小野寺美緒、小山富子、岡本宏明、伊藤清顕、溝上雅史
    • Total Pages
      6
    • Publisher
      メディカルトリビューン
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Book] コホート研究からみたウイルス性肝炎の解明 全国調査からみたB型慢性肝炎の病態2013

    • Author(s)
      伊藤清顕、溝上雅史
    • Total Pages
      9
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Book] 医学のあゆみ B型肝炎ー最新治療コンセンサス Genotype AによるB型急性肝炎の拡大とその特徴2012

    • Author(s)
      伊藤清顕、溝上雅史
    • Total Pages
      6
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Book] 化学療法の領域増刊号 HBV遺伝子型とB型急性肝炎2012

    • Author(s)
      伊藤清顕、溝上雅史
    • Total Pages
      9
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Journal Article] Virological and Clinical Characteristics of Hepatitis B Virus Genotype A2018

    • Author(s)
      Ito Kiyoaki、Yoneda Masashi、Sakamoto Kazumasa、Mizokami Masashi
    • Journal Title

      Journal of Gastroenterology

      Volume: 53 Issue: 1 Pages: 18-26

    • DOI

      10.1007/s00535-017-1367-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09380
  • [Journal Article] Geographic distribution and characteristics of genotype A hepatitis B virus infection in acute and chronic hepatitis B patients in Japan.2016

    • Author(s)
      Ito, K, Yotsuyanagi H, Sugiyama M, Yatsuhashi H, Karino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Tanaka Y, Mita E, Yamamoto K, Michitaka K, Maeshiro T, Tanuma J, Korenaga M, Murata K, Masaki N, Koike K, Mizokami M.
    • Journal Title

      J Gastroenterology and Hepatology

      Volume: 31 Issue: 1 Pages: 180-189

    • DOI

      10.1111/jgh.13030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461028, KAKENHI-PROJECT-26461027
  • [Journal Article] Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease.2016

    • Author(s)
      Shoji H, Yoshio S, Mano Y, Kumagai E, Sugiyama M, Korenaga M, Arai T, Itokawa N, Atsukawa M, Aikata H, Hyogo H, Chayama K, Ohashi T, Ito K, Yoneda M, Nozaki Y, Kawaguchi T, Torimura T, Abe M, Hiasa Y, Kamiyama T, Fukai M, Taketomi A, Mizokami M, Kanto T*
    • Journal Title

      Scientific Reports

      Volume: 6:28814 Issue: 1 Pages: 1-10

    • DOI

      10.1038/srep28814

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461028, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09007, KAKENHI-PROJECT-16K09388
  • [Journal Article] Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease.2016

    • Author(s)
      Kumagai E, Mano Y, Yoshio S, Shoji H, Sugiyama M, Korenaga M, Ishida T, Arai T, Itokawa N, Atsukawa M, Hyogo H, Chayama K, Ohashi T, Ito K, Yoneda M, Kawaguchi T, Torimura T, Nozaki Y, Watanabe S, Mizokami M, Kanto T*.
    • Journal Title

      Scientific Reports

      Volume: 6:35282 Issue: 1 Pages: 1-11

    • DOI

      10.1038/srep35282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Journal Article] Multicenter cooperative case survey of Hepatitis B virus reactivation by chemotherapeutic agents.2015

    • Author(s)
      Takahashi H, Ikeda M, Kumada T, Osaki Y, Kondo S, Kusumoto S, Ohkawa K, Nadano S, Furuse J, Kudo M, Ito K, Yokoyama M, Okusaka T, Shimoyama M, Mizokami M
    • Journal Title

      Hepatol Res

      Volume: Jan 27 Issue: 12 Pages: 1220-1227

    • DOI

      10.1111/hepr.12496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-24591428
  • [Journal Article] Use of nucleotide analogs in patients with chronic hepatitis B in Nepal: A prospective cohort study in a single hospital.2015

    • Author(s)
      Masaki N, Shrestha PK, Nishimura S, Ito K, Sugiyama M, Mizokami M
    • Journal Title

      Hepatol Res

      Volume: Jan 12 Issue: 12 Pages: 1163-1169

    • DOI

      10.1111/hepr.12482

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-15H05289
  • [Journal Article] IL28B polymorphisms and clinical implications for hepatitis C virus infection in Uzbekistan2014

    • Author(s)
      Khudayberganova D, Sugiyama M, Masaki N, Nishida N, Mukaide M, Sekler D, Latipov R, Nataliya K, Dildora S, Sharapov S, Usmanova G, Raxmanov M, Musabaev E, Mizokami M
    • Journal Title

      PLoS One

      Volume: 24;9 Issue: 3 Pages: e93011-e93011

    • DOI

      10.1371/journal.pone.0093011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-24790728, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-25291103
  • [Journal Article] Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ ribavirin therapy in chronic hepatitis C patients2014

    • Author(s)
      Murata K, Sugiyama M, Kimura T, Yoshio S, Kanto T, Kirikae I, Saito H, Aoki Y, Hiramine S, Matsui T, Ito K, Korenaga M, Imamura M, Masaki N, Mizokami M
    • Journal Title

      J Gastroenterol

      Volume: 49(1) Issue: 1 Pages: 126-37

    • DOI

      10.1007/s00535-013-0814-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-25860574
  • [Journal Article] Association of serum IFN-λ3 with inflammatory and fibrosis markers in patients with chronic hepatitis C virus infection.2014

    • Author(s)
      Aoki Y, Sugiyama M, Murata K, Yoshio S, Kurosaki M, Hashimoto S, Yatsuhashi H, Nomura H, Kang JH, Takeda T, Naito S, Kimura T, Yamagiwa Y, Korenaga M, Imamura M, Masaki N, Izumi N, Kage M, Mizokami M, Kanto T.
    • Journal Title

      J Gastroenterol

      Volume: - Issue: 8 Pages: 894-902

    • DOI

      10.1007/s00535-014-1023-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Journal Article] New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia.2014

    • Author(s)
      Nishida N, Sawai H, Kashiwase K, Minami M, Sugiyama M, Seto WK, Yuen MF, Posuwan N, Poovorawan Y, Ahn SH, Han KH, Matsuura K, Tanaka Y, Kurosaki M, Asahina Y, Izumi N, Kang JK, (省略), Tokunaga K, and Mizokami M
    • Journal Title

      PLoS One

      Volume: 9 Issue: 2 Pages: e86449-e86449

    • DOI

      10.1371/journal.pone.0086449

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22133008, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-23590985, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24590980, KAKENHI-PROJECT-24790728, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25461010, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860574, KAKENHI-PROJECT-25870178, KAKENHI-PROJECT-26461027, KAKENHI-PROJECT-26670378, KAKENHI-PROJECT-25291103
  • [Journal Article] Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)2014

    • Author(s)
      Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T
    • Journal Title

      Hepatology

      Volume: 59 Issue: 5 Pages: 1726-1737

    • DOI

      10.1002/hep.26982

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PUBLICLY-24102537, KAKENHI-ORGANIZER-24115001, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25860574
  • [Journal Article] Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C2014

    • Author(s)
      Masaki N, Sugiyama M, Shimada N, Tanaka Y, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Komatsu M, Masaki T, Enomoto N, Yoneda M, Murata K, Ito K, Koike K, Mizokami M.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 29 Issue: 12 Pages: 1996-2005

    • DOI

      10.1111/jgh.12646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25461014
  • [Journal Article] Risk factors for long-term persistence of serum hepatitis B surface antigen following acute hepatitis B virus infection in Japanese adults2014

    • Author(s)
      Ito K, Yotsuyanagi H, Yatsuhashi H, Karino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Mita E, Yamamoto K, Michitaka K, Maeshiro T, Tanuma J, Tanaka Y, Sugiyama M, Murata K, Masaki N, Mizokami M; Japanese AHB Study Group
    • Journal Title

      Hepatology

      Volume: 59 Issue: 1 Pages: 89-97

    • DOI

      10.1002/hep.26635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-24591002, KAKENHI-PROJECT-25860574
  • [Journal Article] Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus2013

    • Author(s)
      Yoshio S, Kanto T, Kuroda S, Matsubara T, Higashitani K, Kakita N, Ishida H, Hiramatsu N, Nagano H, Sugiyama M, Murata K, Fukuhara T, Matsuura Y, Hayashi N, Mizokami M, Takehara T
    • Journal Title

      Hepatology

      Volume: 57 Issue: 5 Pages: 1705-15

    • DOI

      10.1002/hep.26182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-25460994, KAKENHI-PROJECT-25860574
  • [Journal Article] High levels of hepatitis B virus after the onset of disease lead to chronic infection in patients with acute hepatitis B.2013

    • Author(s)
      Yotsuyanagi H, Ito K, Yamada N, Takahashi H, Okuse C, Yasuda K, Su¬zuki M, Moriya K, Mizokami M, Miyakawa Y, Koike K.
    • Journal Title

      Clinical Infectious Diseases

      Volume: 57 Issue: 7 Pages: 935-942

    • DOI

      10.1093/cid/cit348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590553, KAKENHI-PROJECT-24591002
  • [Journal Article] Targeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infection2013

    • Author(s)
      Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, Mizokami M, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M
    • Journal Title

      PLoS One

      Volume: 8 Issue: 3 Pages: e59611-e59611

    • DOI

      10.1371/journal.pone.0059611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PUBLICLY-23114511
  • [Journal Article] A Serum A"sweet-doughnut" protein facilitates fibrosis evaluation and therapy assessment in patients with hepatitis.2013

    • Author(s)
      Kuno A, Ikehara Y, Tanaka Y, Ito K, Matsuda A, Sekiya S, Hige S, Sakamoto M, Kage M, Mizokami M, Narimatsu H
    • Journal Title

      Sci Rep

      Volume: 3 Issue: 1 Pages: 1065-1065

    • DOI

      10.1038/srep01065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Journal Article] Hepatitis C virus kinetics by administration of pegylated interferon-lin human and chimeric mice carrying human hepatocytes with variants of the IL28B gene2012

    • Author(s)
      Watanabe T, Sugauchi F, Tanaka Y, Matsuura K, Yatsuhashi H, Murakami S, Iijima S, Iio E, Sugiyama M, Shimada T, Kakuni M, Kohara M, Mizokami M
    • Journal Title

      Gut

      Volume: Nov 7 Issue: 9 Pages: 1340-6

    • DOI

      10.1136/gutjnl-2012-302553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790664, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23790804, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25860574
  • [Journal Article] 【 C 型肝炎個別化医療のための宿主因子, ウイルス因子】IL-28B 遺伝子周囲に存在する SNPs の機能解析2012

    • Author(s)
      杉山真也, 溝上雅史
    • Journal Title

      消化器内科

      Volume: 55 (2) Pages: 263-270

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Development of specific and quantitative real-time detection PCR and immunoassays for λ3-interferon2012

    • Author(s)
      Sugiyama M, Kimura T, Naito S, Mukaide M, Shinauchi T, Ueno M, Ito K, Murata K, Mizokami M
    • Journal Title

      Hepatol Res

      Volume: 42(11) Issue: 11 Pages: 1089-99

    • DOI

      10.1111/j.1872-034x.2012.01032.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255
  • [Journal Article] C 型慢性肝炎に対するインターフェロン α/ リバビリン治療効果を規定する宿主因子の発見とその臨床的意義2012

    • Author(s)
      溝上雅史
    • Journal Title

      肝臓フォーラム記録集

      Volume: 2011 Pages: 7-23

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] LecT-Hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients2012

    • Author(s)
      Ito K, Kuno A, Ikehara Y, Sugiyama M, Saito H, Aoki Y, Matsui T, Imamura M, Korenaga M, Murata K, Masaki N, Tanaka Y, Hige S, Izumi N, Kurosaki M, Nishiguchi S, Sakamoto M, Kage M, Narimatsu H, Mizokami M
    • Journal Title

      Hepatology

      Volume: 56 Issue: 4 Pages: 1448-56

    • DOI

      10.1002/hep.25815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255, KAKENHI-PROJECT-24590498
  • [Journal Article] Development of new IL28B genotyping method using invader plus assay.2012

    • Author(s)
      Kani S,Tanaka Y.
    • Journal Title

      Microbiol Immunol.

      Volume: 56(5) Issue: 5 Pages: 318-323

    • DOI

      10.1111/j.1348-0421.2012.00439.x

    • NAID

      40019309986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390151, KAKENHI-PROJECT-23390117
  • [Journal Article] 急展開する C 型肝炎ウイルスの研究と臨床 GWAS により発見されたIL28B を中心に2012

    • Author(s)
      溝上雅史
    • Journal Title

      小児感染免疫

      Volume: 24 (2) Pages: 207-213

    • NAID

      10030801524

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region2012

    • Author(s)
      Nakano T, Lau G M, Sugiyama M, Mizokami M
    • Journal Title

      Liver Int

      Volume: 32 Pages: 339-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Discovery of critical host factor, IL-28B, associated with response to hepatitis C virus treatment2012

    • Author(s)
      Mizokami M
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 27(3) Issue: 3 Pages: 425-9

    • DOI

      10.1111/j.1440-1746.2011.07054.x

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Increase in platelet count based on inosine triphosphatase genotype during interferon beta plus ribavirin combination therapy.2012

    • Author(s)
      Nomura H, Miyagi Y; Tanimoto H, Yamashita N, Ito K, Masaki N, Mizokami M.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 27 Issue: 9 Pages: 1461-6

    • DOI

      10.1111/j.1440-1746.2012.07171.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] 【 IL-20 以降の新しいインターロイキンの機能と関連疾患】IL-28A/B , IL-29 と疾患2012

    • Author(s)
      杉山真也, 溝上雅史
    • Journal Title

      細胞工学

      Volume: 31 (7) Pages: 782-786

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Factors responsible for the discrepancy between IL28B polymorphism prediction and the viral response to peginterferon plus ribavirin therapy in Japanese chronic hepatitis C patients2012

    • Author(s)
      Saito H, Ito K, Sugiyama M, Matsui T, Aoki Y, Imamura M, Murata K, Masaki N, Nomura H, Adachi H, Hige S, Enomoto N, Sakamoto N, Kurosaki M, Mizokami M, Watanabe S
    • Journal Title

      Hepatol Res

      Volume: 42(10) Issue: 10 Pages: 958-65

    • DOI

      10.1111/j.1872-034x.2012.01013.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
  • [Journal Article] 【 C 型肝炎個別化医療のための宿主因子, ウイルス因子】 C型慢性肝炎に対する PEG-IFN/RBV48 週および 72 週投与の治療効果に関連するIL28B および ITPA 遺伝子多型の解析2012

    • Author(s)
      伊藤清顕, 溝上雅史
    • Journal Title

      消化器内科

      Volume: 55 (2) Pages: 222-227

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] おくすり情報+ α C 型肝炎の薬2012

    • Author(s)
      溝上雅史
    • Journal Title

      きょうの健康

      Volume: 6 (291) Pages: 89-95

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Easy-to-use phylogenetic analysis system for hepatitis B virus infection2011

    • Author(s)
      Sugiyama M, Inui A, Shin-IT, Komatsu H, Mukaide M, Masaki N, Murata K, Ito K, Nakanishi M, Fujisawa T, Mizokami M
    • Journal Title

      Hepatol Res

      Volume: 41(10) Issue: 10 Pages: 936-945

    • DOI

      10.1111/j.1872-034x.2011.00859.x

    • NAID

      10031144168

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255
  • [Journal Article] Multilectin assay for detecting fibrosis-specific glyco-alteration by means of lectin microarray2011

    • Author(s)
      Kuno A, Mizokami M, et al
    • Journal Title

      Clinical Chemistry

      Volume: 57 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] C 型肝炎の治療効果に影響する遺伝子 IL28B2011

    • Author(s)
      平峯智, 林純, 溝上雅史
    • Journal Title

      Medical Practice

      Volume: 28 (10) Pages: 1880-1882

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Clarification of interspousal hepatitis C virus infection in acute hepatitis C patients by molecular evolutionary analyses : Consideration on sexual and non-sexual transmission between spouses2011

    • Author(s)
      Nakamura I, Mizokami M, et al
    • Journal Title

      Hepatology Research

      Volume: 41 Issue: 9 Pages: 838-845

    • DOI

      10.1111/j.1872-034x.2011.00843.x

    • NAID

      10031144156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B2011

    • Author(s)
      Ito K, Mizokami M, et al
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 49 Pages: 1853-1860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Genome-wide association study and clinical application2011

    • Author(s)
      Sugiyama M, Mizokami M
    • Journal Title

      Nihon Rinsho

      Volume: 69 Pages: 80-85

    • NAID

      40018838444

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin2011

    • Author(s)
      Kurosaki M, Mizokami M, et al
    • Journal Title

      Antiviral Therapy

      Volume: 16 Pages: 685-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection.2011

    • Author(s)
      Yuen MF, Tanaka Y, Sugauchi F, Mizokami M.
    • Journal Title

      Clin Infect Dis.

      Volume: 52(5) Pages: 624-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection.2011

    • Author(s)
      Yuen MF, Tanaka Y, Sugauchi F, Mizokami M. et al.
    • Journal Title

      Clin Infect Dis 52(5)

      Pages: 624-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] The origin and evolution of hepatitis C virus2011

    • Author(s)
      Nakano T, Mizokami M
    • Journal Title

      Nihon Rinsho

      Volume: 69 Pages: 35-40

    • NAID

      40018838436

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] 【ウイルス肝炎診療の変貌 近づく疾患克服】 C 型肝炎 治療効果予測とオーダーメイド治療SNP が決定する治療効果 IL28B およびITPA SNPs2011

    • Author(s)
      伊藤清顕, 溝上雅史
    • Journal Title

      肝・胆・膵

      Volume: 62 (2) Pages: 315-324

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Host sphingolipid biosynthesis is a promising therapeutic target for the inhibition of hepatitis B virus replication2011

    • Author(s)
      Tatematsu K, Mizokami M, et al
    • Journal Title

      Journal of Medical Virology

      Volume: 83 Issue: 4 Pages: 587-593

    • DOI

      10.1002/jmv.21970

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23890255
  • [Journal Article] Reactivation of hepatitis B virus following rituximab-plus-steroid combination chemotherapy.2011

    • Author(s)
      Kusumoto S, Tanaka Y, Mizokami M.
    • Journal Title

      J Gastroenterol.

      Volume: 46(1) Pages: 9-16

    • NAID

      10029026408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] 【新時代のウイルス性肝炎学 基礎・臨床研究の進歩】 C型肝炎 C 型肝炎ウイルス研究の進歩C 型肝炎ウイルス研究技術の進歩 ゲノムワイド関連解析とその応用2011

    • Author(s)
      杉山真也, 溝上雅史
    • Journal Title

      日本臨床

      Volume: 69 Pages: 80-85

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B2011

    • Author(s)
      Ito K, Higami K, Masaki N, Sugiyama M, Mukaide M, Saito H, Aoki Y, Sato Y, Imamura M, Murata K, Nomura H, Hige S, Adachi H, Hino K, Yatsuhashi H, Orito E, Kani S, Tanaka Y, Mizokami M
    • Journal Title

      J Clin Microbiol

      Volume: 49 Issue: 5 Pages: 1853-60

    • DOI

      10.1128/jcm.02139-10

    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005
  • [Journal Article] 【 Genome Wide Association Study は肝胆膵診療をいかに変えるか ? 】 GWAS 研究の進め方2011

    • Author(s)
      西田奈央, 溝上雅史
    • Journal Title

      肝・胆・膵

      Volume: 62 (5) Pages: 879-886

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Novel findings for the development of drug therapy for various liver diseases : Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C2011

    • Author(s)
      Sugiyama M, Mizokami M, et al
    • Journal Title

      Journal of Pharmacological Science

      Volume: 115 Pages: 263-269

    • NAID

      10029892326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] JPHC Study Group. Impact of viral load of hepatitis C on the incidence of hepatocellular carcinoma : A population-based cohort study (JPHC Study)2011

    • Author(s)
      Ishiguro S, Mizokami M, et al
    • Journal Title

      Cancer Letter

      Volume: 300 Pages: 173-179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan.2011

    • Author(s)
      Kusakabe A, Tanaka Y, Mizokami M. et al.
    • Journal Title

      J Gastroenterol 46(1)

      Pages: 117-124

    • NAID

      10029026880

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Phenotype-dependent production of des-γ-carboxy prothrombin in hepatocellular carcinoma2011

    • Author(s)
      Suzuki H, Mizokami M, et al
    • Journal Title

      Journal of Gastroenterology

      Volume: 46 Pages: 1219-1229

    • NAID

      10030294539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Genetic variation of the IL-28B promoter affecting gene expression2011

    • Author(s)
      Sugiyama M, Mizokami M, et al
    • Journal Title

      PLoS ONE

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] 話題の疾患と治療 HCV 治療の有効性と IL28B( インターフェロン λ)2011

    • Author(s)
      正木尚彦, 伊藤清顕, 溝上雅史
    • Journal Title

      感染・炎症・免疫

      Volume: 40 (4) Pages: 380-383

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] LecT-Hepa : A triplex lectin-antibody sandwich immunoassay for estimating the progression dynamics of liver fibrosis assisted by a bedside clinical chemistry analyzer and an automated pretreatment machine2011

    • Author(s)
      Kuno A, Mizokami M, et al
    • Journal Title

      Clinca Chimca Acta

      Volume: 412 Pages: 1767-1772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region2011

    • Author(s)
      Nakano T, Mizokami M, et al
    • Journal Title

      Liver International

      Volume: 32 Issue: 2 Pages: 339-345

    • DOI

      10.1111/j.1478-3231.2011.02684.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23890255
  • [Journal Article] Novel findings for the development of drug therapy for various liver diseases : Genetic variation in IL-28B is associated with response to the therapy for chronic hepatitis C2011

    • Author(s)
      Sugiyama M, Tanaka Y, Nakanishi M, Mizokami M
    • Journal Title

      J Pharmacol Sci

      Volume: 115(3) Pages: 263-9

    • NAID

      10029892326

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Reactivation of hepatitis B virus following rituximab-plus-steroid combination chemotherapy2011

    • Author(s)
      Kusumoto S, Mizokami M, et al
    • Journal Title

      Journal of Gastroenterology

      Volume: 46 Pages: 9-16

    • NAID

      10029026408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011

    • Author(s)
      Sugauchi F, Tanaka Y, Mizokami M. et al.
    • Journal Title

      J Med Virol 83(3)

      Pages: 412-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] 【遺伝子多型による消化器疾患の理解】 遺伝子多型は HCV 肝炎の病態, 薬剤の効果にどう影響するのか2011

    • Author(s)
      村田一素, 伊藤清顕, 溝上雅史
    • Journal Title

      分子消化器病

      Volume: 8 (3) Pages: 227-232

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b2011

    • Author(s)
      Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
    • Journal Title

      J Med Virol

      Volume: 83 Issue: 5 Pages: 871-878

    • DOI

      10.1002/jmv.22038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590833, KAKENHI-PROJECT-22390151, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22710191, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23790778
  • [Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C2011

    • Author(s)
      Tanaka Y, Mizokami M, et al
    • Journal Title

      Human Molecular Genetics

      Volume: 20 Pages: 3507-3516

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011

    • Author(s)
      Sugauchi F, Tanaka Y, Mizokami M.
    • Journal Title

      J Med Virol.

      Volume: 83(3) Pages: 412-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion.2011

    • Author(s)
      Wu S, Tanaka Y, Mizokami M. et al.
    • Journal Title

      J Hepatol 54(1)

      Pages: 19-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011

    • Author(s)
      Sugauchi F, Mizokami M.
    • Journal Title

      J Med Virol.

      Volume: 83 Pages: 412-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Journal Article] Suppressor of cytokine signal 3 and IL28 genetic variation predict the viral response to peginterferon and ribavirin2011

    • Author(s)
      Miyaaki H, Mizokami M, et al
    • Journal Title

      Hepatology Research

      Volume: 41 Issue: 12 Pages: 1216-1222

    • DOI

      10.1111/j.1872-034x.2011.00881.x

    • NAID

      10031144200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors2011

    • Author(s)
      Kurosaki M, Sakamoto N, Nakagawa M, Watanabe M, et al.
    • Journal Title

      J Hepatol

      Volume: 54 Issue: 3 Pages: 439-448

    • DOI

      10.1016/j.jhep.2010.07.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590836, KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23390117
  • [Journal Article] PEG-IFN& RBV併用療法の治療効果に寄与するヒト遺伝子多型2011

    • Author(s)
      杉山真也, 溝上雅史
    • Journal Title

      肝・胆・膵

      Volume: 61 Pages: 68-75

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Management of hepatitis B : Consensus of the Japan Society of Hepatology 20092011

    • Author(s)
      Yokosuka O, Mizokami M, et al
    • Journal Title

      Hepatology Research

      Volume: 41 Issue: 1 Pages: 1-21

    • DOI

      10.1111/j.1872-034x.2010.00739.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Recommendation of Lamivudine-to-Entecavir switching treatment in chronic hepatitis B responders : Randomized controlled trial2011

    • Author(s)
      Matsuura K, Tanaka Y, Mizokami M.
    • Journal Title

      Hepatol Res.

      Volume: (印刷中)

    • NAID

      10031144118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Genome-wide association study on and the clinical application to chronic hepatitis C2011

    • Author(s)
      Sugiyama M, Mizokami M
    • Journal Title

      Uirusu

      Volume: 61 Pages: 15-24

    • NAID

      10029357046

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Prevalence of amino acid mutation in hepatitis C virus core region among Japanese volunteer blood donors2011

    • Author(s)
      Furui Y, Mizokami M, et al
    • Journal Title

      Journal of Medical Virology

      Volume: 83 Issue: 11 Pages: 1924-1929

    • DOI

      10.1002/jmv.22216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005
  • [Journal Article] Virological Characteristics of hepatitis B virus on reactivation of hepatitis B in individuals with resolved infection.2011

    • Author(s)
      Sugauchi F, Mizokami M.
    • Journal Title

      J Med Virol. 83

      Pages: 412-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Journal Article] Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors2011

    • Author(s)
      Kurosaki M, Mizokami M, et al
    • Journal Title

      Journal of Hepatology

      Volume: 54 Pages: 439-448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Transmissibility of hepatitis B virus (HBV) infection through blood transfusion from blood donors with occult HBV infection.2011

    • Author(s)
      Yuen MF, Sugauchi F, Mizokami M.
    • Journal Title

      Clin Infect Dis.

      Volume: 52 Pages: 624-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Journal Article] Cross-species transmission of gibbon and orangutan hepatitis B virus to uPA/SCID mice with human hepatocytes2011

    • Author(s)
      Sa-Nguanmoo P, Mizokami M, et al
    • Journal Title

      Virus Research

      Volume: 158 Pages: 209-215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion2011

    • Author(s)
      Wu S, Mizokami M, et al
    • Journal Title

      Journal of Hepatology

      Volume: 54 Pages: 19-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan.2011

    • Author(s)
      Kusakabe A, Tanaka Y, Mizokami M.
    • Journal Title

      J Gastroenterol.

      Volume: 46(1) Pages: 117-124

    • NAID

      10029026880

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Hepatitis B virus genotype and the mutation related to clinical outcome2011

    • Author(s)
      Sugiyama M, Mizokami M
    • Journal Title

      Nihon Rinsho

      Volume: 69 Pages: 350-355

    • NAID

      40018838496

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] ゲノミクスの手法に基づく HCV 感染者の IFN 治療効果の研究2011

    • Author(s)
      杉山真也, 溝上雅史
    • Journal Title

      ウイルス

      Volume: 61 (1) Pages: 15-24

    • NAID

      10029357046

    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Recommendation of lamivudine-to-entecavir switching treatment in chronic hepatitis B responders : Randomized controlled trial2011

    • Author(s)
      Matsuura K, Mizokami M, et al
    • Journal Title

      Hepatology Research

      Volume: 41 Issue: 6 Pages: 505-511

    • DOI

      10.1111/j.1872-034x.2011.00807.x

    • NAID

      10031144118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Clinical significance of hepatitis B virus (HBV)-DNA monitoring to detect HBV reactivation after systemic chemotherapy2011

    • Author(s)
      Kusumoto S, Mizokami M, et al
    • Journal Title

      Journal of Clinical Oncology

      Volume: 29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Journal Article] Genetic variation of the IL-28B promoter affecting gene expression2011

    • Author(s)
      Sugiyama M, Tanaka Y, Wakita T, Nakanishi M, Mizokami M
    • Journal Title

      PLoS One

      Volume: 6(10) Issue: 10 Pages: e26620-e26620

    • DOI

      10.1371/journal.pone.0026620

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23659407
  • [Journal Article] Occult hepatitis B in the genotype H-infected Nahuas and Huichol native Mexican population.2010

    • Author(s)
      Roman S, Tanaka Y, Mizokami M. et al.
    • Journal Title

      J Med Virol 82(9)

      Pages: 1527-1536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Evolution of hepatitis B genotype C viral quasi-species during hepatitis B e antigen seroconversion.2010

    • Author(s)
      Wu S, Tanaka Y, Mizokami M.
    • Journal Title

      J Hepatol.

      Volume: 54(1) Pages: 19-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Reactivation of hepatitis B virus in HBsAg-negative patients with multiple myeloma : two case reports.2010

    • Author(s)
      Yoshida T, Sugauchi F, Mizokami M.
    • Journal Title

      Int J Hematol.

      Volume: 91 Pages: 844-849

    • NAID

      10026511317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Journal Article] Occult hepatitis B in the genotype H-infected Nahuas and Huichol native Mexican population.2010

    • Author(s)
      Roman S, Tanaka Y, Mizokami M.
    • Journal Title

      J Med Virol.

      Volume: 82(9) Pages: 1527-1536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Distribution of Hepatitis B Virus Genotypes among Patients with Chronic Infection in Japan Shifting toward an Increase of Genotype A.2009

    • Author(s)
      Matsuura K, Sugauchi F, Mizokami M.
    • Journal Title

      J Clin Microbiol. 47

      Pages: 1476-1483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Journal Article] Distribution of Hepatitis B Virus Genotypes among Patients with Chronic Infection in Japan Shifting toward an Increase of Genotype A.2009

    • Author(s)
      Matsuura K, Tanaka Y, Mizokami M. et al.
    • Journal Title

      J Clin Microbiol 47(5)

      Pages: 1476-1483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Journal Article] Characteristics of hepatitis B virus genotype G coinfected with genotype H in Chimeric Mice Carrying Human Hepatocytes.2008

    • Author(s)
      Tanaka Y, Mizokami M. et al.
    • Journal Title

      Virology 376(2)

      Pages: 408-415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Patent] インターフェロン治療効果予測方法2013

    • Inventor(s)
      溝上雅史、杉山真也、 村田一素、木村達治、内藤成子
    • Industrial Property Rights Holder
      溝上雅史、杉山真也、 村田一素、木村達治、内藤成子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-11-01
    • Acquisition Date
      2013-11-01
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Patent] インターフェロン治療効果予測方法2013

    • Inventor(s)
      溝上雅史, 杉山真也, 村田一素, 木村達治, 内藤成子
    • Industrial Property Rights Holder
      溝上雅史, 杉山真也, 村田一素, 木村達治, 内藤成子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-11-01
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Patent] B型肝炎ウイルス群を検出し、遺伝子多様性を評価するためのオリゴヌクレオチドのセット、並びにそれを用いた方法2011

    • Inventor(s)
      溝上雅史、杉山真也、新井理、田村卓郎
    • Industrial Property Rights Holder
      国立国際医療研究センター、ビッツ株式会社
    • Filing Date
      2011-12-19
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Patent] IL-28Bの分析方法2011

    • Inventor(s)
      溝上雅史、杉山真也、木村達治
    • Industrial Property Rights Holder
      国立国際医療研究センター、特殊免疫研究所
    • Industrial Property Number
      2011-287603
    • Filing Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Patent] C型肝炎患者の経過予測方法2011

    • Inventor(s)
      溝上雅史、杉山真也
    • Industrial Property Rights Holder
      国立国際医療研究センター
    • Industrial Property Number
      2011-211647
    • Filing Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Development of Novel Anti-viral Agents against Hepatitis B Virus by using an siRNA Screening Panel Targeting the Carbohydrate Synthesis System.2016

    • Author(s)
      Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Iijima S, Tanaka Y, Tong S, Mizokami M, Narimatsu H
    • Organizer
      APDW 2016
    • Place of Presentation
      神戸
    • Year and Date
      2016-11-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09380
  • [Presentation] Interleukin-34 as a fibroblast-derived marker of liver fibrosis in patients with non-alcoholic fatty liver disease.2016

    • Author(s)
      Shoji H, Yoshio S, Mano Y, Kumagai E, Doi H, Sugiyama M, Korenaga M, Arai T, Itokawa N, Atsukawa M, Aikata H, Hyogo H, Chayama K, Ohashi T, Ito K, Yoneda M, Nozaki Y, Kawaguchi T, Torimura T, Abe M, Hiasa Y, Fukai M, Kamiyama T, Taketomi A, Mizokami M and Kanto T.
    • Organizer
      The Liver Meeting 2016: The 67th Annual Meeting of AASLD.
    • Place of Presentation
      Boston, USA
    • Year and Date
      2016-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] Pro-angiogenic Tie2-expressing monocytes/TEMs as a biomarker of the response to sorafenib in patients with advanced hepatocellular carcinoma.2016

    • Author(s)
      Shoji H, Yoshio S, Mano Y, Kumagai E, Doi H, Sugiyama M, Osawa Y, Kimura K, Arai T, Itokawa N, Atsukawa M, Fukai M, Taketomi A, Mizokami M and Kanto T.
    • Organizer
      Japan Society of Hepatology, Single Topic Conference, Hepatocellular carcinoma
    • Place of Presentation
      金沢市
    • Year and Date
      2016-09-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] 非アルコール性脂肪性肝疾患におけるマクロファージ関連肝線維化マーカーIL-34の検討2016

    • Author(s)
      正司裕隆, 溝上雅史, 考藤達哉.
    • Organizer
      第24回日本消化器関連学会週間 (JDDW2016)
    • Place of Presentation
      神戸市
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] Development of Novel Anti-viral Agents against Hepatitis B Virus by using an siRNA Screening Panel Targeting the Carbohydrate Synthesis System.2016

    • Author(s)
      Ito K, Yoneda M, Angata K, Watashi K, Wakita T, Iijima S, Tanaka Y, Tong S, Mizokami M, Narimatsu H
    • Organizer
      2016 International Meeting on Molecular Biology of Hepatitis B Viruses
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09380
  • [Presentation] 非アルコール性脂肪性肝疾患におけるIL-34 新規マクロファージ関連肝線維化マーカー.2016

    • Author(s)
      正司裕隆, 由雄祥代, 間野洋平, 熊谷恵理奈, 土肥弘義, 杉山真也, 是永匡紹, 武冨紹信, 溝上雅史, 考藤達哉.
    • Organizer
      第52回日本肝臓学会総会
    • Place of Presentation
      千葉県
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] Cancer-associated or cirrhosis fibroblasts recovered from hepatocellular carcinoma promote macrophages and cancer cells to progressive phenotype.2015

    • Author(s)
      Mano Y, Kanto T, Shoji H, Yoshio S, Sugiyama M, Osawa Y, Kimura K, Shirabe K, Maehara Y, Mizokami M.
    • Organizer
      Annual Meeting of American Association of Cancer Research (AACR)
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2015-04-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese.2015

    • Author(s)
      Nishida N, Ohashi J, Sugiyama M, Tsuchiura T, Yamamoto K, Hino K, Honda M, Kaneko S, Yatsuhashi H, Koike K, Yokosuka O, Tanaka E, Taketomi A), Kurosaki M, Izumi N, Sakamoto N, Eguchi Y, Sasazuki T, Tokunaga K, Kanto T, Mizokami M
    • Organizer
      The American Association for the Study of Liver Diseases (AASLD), 66th Annual Meeting and Postgraduate Course,
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2015-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] Development of IFNλ3 Quantification in the Serum and Its Clinical Significance - Genome-wide Association Study and Clinical Application in Hepatitis -2013

    • Author(s)
      Mizokami M
    • Organizer
      The 2013 Italy-Japan Liver Workshop Hepatitis, Steatosis and Hepatocellular Carcinoma : Molecular basis and llinical Links
    • Place of Presentation
      Marsala Italy
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Development of IFNλ3 Quantification in the Serum and Its Clinical Significance- Genome-wide Association Study and Clinical Application in Hepatitis-2013

    • Author(s)
      Mizokami M
    • Organizer
      Japan-Russia International Workshop 2013 (JRIW2013)
    • Place of Presentation
      東京
    • Year and Date
      2013-10-27
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Houw shouldwe treat HCV with the genetic characteristics of the virus and the human body ?2013

    • Author(s)
      Mizokami M
    • Organizer
      Research to practice conference : new tecniques in viral infection diagnosis, treatment and prevention Bukhara
    • Place of Presentation
      Uzbekistan seminar
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] What interferon-λ has taught us in hepatitis C virus and host genomics?2013

    • Author(s)
      Mizokami M
    • Organizer
      Avison Biomedical Symposium 2012 "Virus and Human Disease"
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2013-02-03
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Number of peripheral BDCA4+dendritic cells determines the response to pegylated interferon/ribavirin therapy in chronic hepatitis C patients2013

    • Author(s)
      Murata K, Sugiyama M, Kimura T, Takeda T, Yoshio S, Aoki Y, Nishida N, Yamagiwa Y, Korenaga M, Imamura M, Kanto T, Masaki N, Mizokami M
    • Organizer
      The 64th annual meeting of the American association for the study of liver diseases
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Polymorphisms consisting of (TA)n dinucleotide repeat near IL28B gene could improve the predictive value for HCV spontaneous clearance with IL28B SNPs2013

    • Author(s)
      Sugiyama M, Hiramine S, Furusho N, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K,, Masaki N, Mizokami M
    • Organizer
      The 64th annual meeting of the American association for the study of liver diseases
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Pre-treatment levels of serum IFN-3 more accurately predict sustained virological response by pegylated interferon/ribavirin therapy than IL28B genotyping in chronic hepatitis C patients2013

    • Author(s)
      Aoki Y, Murata K,, Sugiyama M, Kimura T, Takeda T, Yoshio S, Yamagiwa Y, Korenaga M, Imamura M, Kanto T, Masaki N, Mizokami M
    • Organizer
      The 64th annual meeting of the American association for the study of liver diseases
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] IL28B and other genetic targets for HBV therapy2013

    • Author(s)
      Mizokami M
    • Organizer
      APASL Liver Week Sinpapore
    • Year and Date
      2013-03-09
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] HBVジェノタイプの最近の動向と病態との関連2013

    • Author(s)
      伊藤清顕、溝上雅史
    • Organizer
      第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Presentation] Human BDCA3+DC contribute to the induction of intrahepatic ISGs as a potent IFN- producer in HCV infection2013

    • Author(s)
      Yoshio S, Kanto T, Matsubara T, Sugiyama M, Murata K,, Fukuhara T, Matsuura Y, Mizokami M, Hayashi N, Takehara T
    • Organizer
      The 64th annual meeting of the American association for the study of liver diseases
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] B型急性肝炎の慢性化に関する検討2013

    • Author(s)
      伊藤清顕、四柳宏、溝上雅史
    • Organizer
      第40回日本肝臓学会西部会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Presentation] Human BDCA3+dendritic cells as a potent interferon- producer and an enhancer of helper T cell and natural killer cell responsive to hepatitis C virus2013

    • Author(s)
      Yoshio S, Kanto T, Matsubara T, Sugiyama M, Murata K,, Mizokami M, Hayashi N, Takehara T
    • Organizer
      The 64th annual meeting of the American association for the study of liver diseases
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Risk factors for long-term persistence of serum hepatitis B surface antigen following acute hepatitis B virus infection in Japanese adults.2013

    • Author(s)
      Ito K, Yotsuyanagi H, Yatsuhashi H, Krino Y, Takikawa Y, Saito T, Arase Y, Imazeki F, Kurosaki M, Umemura T, Ichida T, Toyoda H, Yoneda M, Mita E, Yamamoto K, Michitaka K, Meshiro T, Tanuma J, Tanaka Y, Sugiyama M, Murata K, Masaki N, Mizokami M
    • Organizer
      The 64th Annual Meeting of the American Association for the Study of Liver Diseases
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Presentation] Significant roles of IFN-3 with reciprocal levels in serum and ex vivo stimulated PBMC in chronic hepatitis C2013

    • Author(s)
      Aoki Y, Murata K,, Sugiyama M, Kimura T, Takeda T, Yoshio S, Nishida N, Yamagiwa Y, Korenaga M, Imamura M, Kanto T, Masaki N, Jong-Hon Kang, Mizokami M
    • Organizer
      The 64th annual meeting of the American association for the study of liver diseases
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Networking for the Promoting One World, One Health for a Better Tomorrow; Prevention and Treatment using Natural Products, Vaccines and Antivirals Surabaya2013

    • Author(s)
      Mizokami M
    • Organizer
      Solved and Unsolved Issues of Anti- HBV or Anti-HCV Therapy in Japan -On the road to HCC prevention- Seminar on Infectious Diseases
    • Place of Presentation
      Indonesia
    • Year and Date
      2013-10-17
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] ITPA gene variants associated with hemolytic anemia and treatment efificiency in pegylated-interferon plus ribavirin therapy for chronic hepatitis C2012

    • Author(s)
      Matsuura K, Tanaka Y, Nishida N, Kurosaki M, Sakamoto A, Enomoto N, Yatsuhashi H, Kaneko S, Tokunaga K, Mizokami M.
    • Organizer
      APASL2012 : 22nd conference of the Asian Pacific association for the study of the liver
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] How did interferon-λ identify and work for treatment for chronic hepatitis C?2012

    • Author(s)
      Mizokami M
    • Organizer
      2nd Xiamen winter symposium Xiamen
    • Place of Presentation
      China
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] スフィンゴ脂質合成経路の阻害によるHBV複製の抑制2012

    • Author(s)
      杉山真也、田中靖人、溝上雅史
    • Organizer
      肝炎ウイルス研究シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2012-03-24
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Host genetic factors on the treatment of chronic hepatitis C APASL20122012

    • Author(s)
      Tanaka Y, Mizokami M
    • Organizer
      22nd conference of the Asian Pacific association for the study of the liver
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2012-02-16
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Different Amount of IFN-λ3 Determines the Outcome of Peg-IFN/RBV Therapy in HCV Patients.2012

    • Author(s)
      Murata K, Sugiyama M, Kimura T, Yoshio S, Kanto T, Kirikae I, Aoki Y, Hiramine S, Matsui T, Korenaga M, Imamura M, Masaki N, Mizokami M.
    • Organizer
      The 10th JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] C型慢性肝炎における臨床背景の違いと治療法選択の現状と展開IP-10値を含めたPEG-IFN/RBV療法における治療予測因子の検討.2012

    • Author(s)
      松浦健太郎, 田中靖人, 飯尾悦子, 日下部篤宣, 新海登, 宮木知克, 野尻俊輔, 渡邊綱正, 藤原圭, 折戸悦朗, 城卓志, 溝上雅史.
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] C型肝炎治療の最前線 IL28B遺伝子多型による治療効果予測不一致に寄与する宿主因子の検討.2012

    • Author(s)
      村田一素, 杉山真也, 溝上雅史.
    • Organizer
      第16回日本肝臓学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Ultrasensitive assay for genotyping of hepatitis B virus by use of an automated DNA extraction instrument.2012

    • Author(s)
      Kirikae I, Ito K, Mukaide M, Sugiyama M, Murata K, Masaki N, Mizokami M.
    • Organizer
      APASL2012 : 22nd conference of the Asian Pacific association for the study of the liver
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Present status and future perspectives of treatment of chronic hepatitis B in Nepal.2012

    • Author(s)
      Masaki N, Shrestha P, Nishimura S, Ito K, Mizokami M.
    • Organizer
      APASL2012 : 22nd conference of the Asian Pacific association for the study of the liver
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] 最新の遺伝子研究からみた肝臓病の現状と個別化医療への展望C型慢性肝炎と自然治癒に関連する第二遺伝要因の探索とその応用.2012

    • Author(s)
      杉山真也, 平峯智, 西田奈央, 伊藤清顕, 村田―素, 正木尚彦, 宇都浩文, 井戸章雄, 坪内博仁, 溝上雅史.
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Iron Metabolism in Hepatitis C.2012

    • Author(s)
      Korenaga M, Hino K, Mizokami M.
    • Organizer
      The 10th JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Identification of interferon-λ and its clinical importance for hepatitis C virus infection2012

    • Author(s)
      Mizokami M
    • Organizer
      Avison Biomedical Symposium 2012
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2012-02-03
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] C型肝炎基礎Toll-like receptor 7 agonist刺激による末梢血リンパ球IFN-λ3誘導とその臨床的意義.2012

    • Author(s)
      村田一素, 杉山真也, 溝上雅史.
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Prospective Multi-center Cohort Study for the Predictive Efficacy of IL28B and ITPA SNPs in Patients with Chronic Hepatitis C Treated by Peginterferon and Ribavirin Therapy.2012

    • Author(s)
      Masaki N, Sugiyama M, Tanaka Y, Shimada N, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Mizokami M.
    • Organizer
      The 10th JSH Single Topic Conference
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Risk factors for long-term persistance of serum hbsag following accute heaptitis B virus infection in Japan.2012

    • Author(s)
      Ito K, Sugiyama M, Murata K, Masaki N, Mizokami M
    • Organizer
      APASL2012 : 22nd conference of the Asian Pacific association for the study of the liver
    • Place of Presentation
      Taipei
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] C型慢性肝炎における臨床背景の違いと治療法選択の現状と展開C型慢性肝炎に対するペグインターフェロン・リハビリン併用療法における個別化医療 多施設共同前向き研究からの考察.2012

    • Author(s)
      正木尚彦, 杉山真也, 田中睛人, 伊藤清顕, 村田一素, 青木孝彦, 斉藤紘昭, 松井哲平, 今村雅俊, 溝上雅史.
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] キメラマウスでのB型肝炎の病態進展に関わる分子機構の検討2011

    • Author(s)
      杉山真也、田中靖人、溝上雅史
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Geographic and Genetic Diversity of Hepatitis B Virus2011

    • Author(s)
      Mizokami M
    • Organizer
      APASL 2011
    • Place of Presentation
      Bangkok Thailand
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] IL-28B遺伝子周囲に存在するSNPsの機能解析と臨床的意義2011

    • Author(s)
      杉山真也、田中靖人、溝上雅史
    • Organizer
      第19回日本消化器関連学会週間
    • Place of Presentation
      福岡
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] Optimizing Treatment for Chronic Hepatitis C -Incorporating Pharmacogenetics into Clinical Practic2011

    • Author(s)
      Mizokami M
    • Organizer
      Integrated Science and Tecnology Clinical Gastroenterology Singapore Plenary lecture Okuda Award
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] ホストのスフィンゴ脂質合成系を標的とした抗HBV薬のキメラマウスにおける検討2011

    • Author(s)
      杉山真也、田中靖人、溝上雅史
    • Organizer
      第19回日本消化器関連学会週間
    • Place of Presentation
      福岡
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-23390117
  • [Presentation] ラミブジン投与例におけるエンテカビル切り替え無作為割り付け試験2010

    • Author(s)
      松浦健太郎、田中靖人、溝上雅史
    • Organizer
      第46回日本肝臓学会総
    • Place of Presentation
      ホテルメトロポリタン山形 (山形市)
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Presentation] A POPULATION-BASEDM COHORT STUDY FOR THE RISK FACTORS OF HCC AMONG HEPATITIS B VIRUS MONOINFECTED SUBJECT IN JAPAN.2010

    • Author(s)
      Kusakabe A, Tanaka Y, Mizokami M.
    • Organizer
      The 61^<st> annual meeting of the AASLD
    • Place of Presentation
      The Hynes Convention Center (Boston USA)
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Presentation] In vivo model using uPA/SCID mice with human hepatocytes to study cross-genotype protection of HBV and a role of HBs antigenmutation in immunity escape2010

    • Author(s)
      Sugauchi F, Mizokami M.
    • Organizer
      The 61^<st> annual meeting of the AASLD
    • Place of Presentation
      The Hynes Convention Center (Boston USA)
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Presentation] ヒト肝細胞置換キメラマウスでのHBV感染による酸化傷害と線維化2010

    • Author(s)
      杉山真也、田中靖人、溝上雅史
    • Organizer
      第46回日本肝臓学会総
    • Place of Presentation
      ホテルメトロポリタン山形 (山形市)
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Presentation] ラミブジン投与例におけるエンテカビル切り替え無作為割り付け試験2010

    • Author(s)
      松浦健太郎, 溝上雅史
    • Organizer
      第46回日本肝臓学会総
    • Place of Presentation
      ホテルメトロポリタン山形(山形市)
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Presentation] ラミブジン投与例におけるエンテカビル切り替え無作為割り付け試験2010

    • Author(s)
      松浦健太郎、菅内文中、溝上雅史
    • Organizer
      第46回 日本肝臓学会総会
    • Place of Presentation
      ホテルメトロポリタン山形(山形市)
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Presentation] A POPULATION-BASED COHORT STUDY FOR THE RISK FACTORS OF HCC AMONG HEPATITIS B VIRUS MONOINFECTED SUBJECT IN JAPAN.2010

    • Author(s)
      Kusakabe A. Mizokami M.
    • Place of Presentation
      The Hynes Convention Center (Boston USA)
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Presentation] ヒト肝細胞キメラマウスにおけるB型肝炎ウイルス感染防御の試み2010

    • Author(s)
      菅内文中、溝上雅史
    • Organizer
      第46回 日本肝臓学会総会
    • Place of Presentation
      ホテルメトロポリタン山形(山形市)
    • Data Source
      KAKENHI-PROJECT-20590788
  • [Presentation] ヒト肝細胞キメラマウスにおけるB型肝炎ウイルス感染防御の試み2010

    • Author(s)
      菅内文中、田中靖人、溝上雅史
    • Organizer
      第46回日本肝臓学会総
    • Place of Presentation
      ホテルメトロポリタン山形 (山形市)
    • Data Source
      KAKENHI-PROJECT-20390213
  • [Presentation] Comprehensive analyses of serum biomarkers associating with the increase of pro-angiogenic Tie2-expressing monocytes in patients with hepatocellular carcinoma.

    • Author(s)
      Hirotaka Shoji, Tatsuya Kanto, Sachiyo Yoshio, Yohei Mano, Masaya Sugiyama, Yoshihiko Aoki, Akinobu Taketomi, Masashi Mizokami
    • Organizer
      1)Annual Meeting American Association for Cancer Research(AACR)
    • Place of Presentation
      Philadelphia (USA)
    • Year and Date
      2015-04-18 – 2015-04-22
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] 肝細胞癌における血管新生関連細胞(Tie2-expressing monocytes)誘導因子の探索

    • Author(s)
      正司裕隆、考藤達哉、間野洋平、青木孝彦、由雄祥代、杉山真也、武冨紹信、溝上雅史
    • Organizer
      2)第51回日本肝臓学会総会
    • Place of Presentation
      ホテル日航熊本(熊本)
    • Year and Date
      2015-05-21 – 2015-05-22
    • Data Source
      KAKENHI-PROJECT-26461028
  • [Presentation] Development of New Anti-Viral Agent Targeting Sugar Chain Synthesis System Associated with Life cycle of Hepatitis B Virus.

    • Author(s)
      Ito K, Yoneda M, Angata K, Tong S, Mizokami M, Narimatsu H
    • Organizer
      2014 International Meeting on Molecular Biology of Hepatitis B Viruses
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      2014-09-03 – 2014-09-06
    • Data Source
      KAKENHI-PROJECT-24591002
  • [Presentation] B型慢性肝炎に関する全国調査結果

    • Author(s)
      伊藤清顕、溝上雅史
    • Organizer
      第20回日本消化器関連学会週間JDDW2012シンポジウム
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24591002
  • 1.  WAKITA Takaji (40280789)
    # of Collaborated Projects: 3 results
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  • 2.  ITO Kiyoaki (50551420)
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    # of Collaborated Products: 34 results
  • 3.  ORITO E (60204294)
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  • 5.  OHNO Tomoyoshi (90264712)
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  • 6.  IINO Shiro (30010309)
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  • 7.  TANAKA Yasuhito (90336694)
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  • 8.  SUGAUCHI Fuminaka (20405161)
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  • 9.  GOJOBORI Takashi (50162136)
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  • 10.  TOKUDOME Shinkan (00037441)
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  • 11.  SUEOKA Eizaburo (00270603)
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  • 12.  ODA Hideaki (40214142)
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  • 13.  TASHIRO Fumio (70089332)
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  • 16.  陳 公超
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  • 17.  陳 剛
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  • 18.  兪 順章
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  • 19.  YU Shun-zhang
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  • 20.  FUAT Kurbanov (10444978)
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  • 21.  MURATA Kazumoto (40345971)
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  • 22.  SUZUKI Yoshiyuki (70353430)
    # of Collaborated Projects: 1 results
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  • 23.  Kanto Tatsuya (80372613)
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  • 24.  IKEO Kazuho (20249949)
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  • 25.  TATENO Yoshio (00202424)
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  • 26.  UEDA Ryuzo (20142169)
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  • 27.  KONDA Yutaka (00419897)
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  • 28.  YOSHIZAWA Hiroshi (30109954)
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  • 29.  加藤 孝宣 (20333370)
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  • 30.  宮本 道子 (40190821)
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  • 31.  伊達 朋子 (40392360)
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  • 33.  相崎 英樹 (00333360)
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  • 35.  石井 孝司 (40280763)
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  • 37.  根路銘 国昭 (00072934)
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  • 39.  星野 洪郎 (00107434)
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  • 40.  下遠野 邦忠 (10000259)
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  • 41.  森山 悦子 (20210198)
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  • 43.  永谷 照男 (40144018)
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  • 44.  久野 敦 (50302287)
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  • 49.  Sakamoto Kazumasa
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  • 51.  Suzuki Sayuri
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  • 52.  CHEN Gong-chao
    # of Collaborated Projects: 1 results
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  • 53.  CHEN Gang
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  • 55.  CHEN Cheng-hsin
    # of Collaborated Projects: 0 results
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  • 56.  中西 真
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  • 57.  村上 周子
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  • 58.  奥瀬 千晃
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  • 59.  渡辺 守
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  • 60.  坂本 直哉
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  • 61.  中川 美奈
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  • 62.  徳永 勝士
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  • 63.  坪田 昭人
    # of Collaborated Projects: 0 results
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