SUGIURA Shigeki 杉浦重樹

Researcher Number	40179130
Other IDs
Affiliation *help	2018 : 奈良県立医科大学, 医学部, 教育教授 2012 – 2017 : 奈良県立医科大学, 医学部, 准教授 2003 – 2005 : Nara Medical University, Faculty of Medicine, Associate Professor, 医学部, 助教授 2003 : 奈良県立医科学大学, 医学部, 助教授 2002 : 奈良県立医科大学, 総合研究施設部, 助教授 … More
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals / Molecular biology Except Principal Investigator Psychiatric science / Neuroscience in general / Risk sciences of radiation and chemicals / 代謝生物化学
Keywords	Principal Investigator 修復 / DNA 損傷 / pSC101 / ｼｸﾛﾌﾞﾀﾝ型ﾀﾞｲﾏｰ / DNA replication / 修復亢進 / CPD / ﾓﾉｸﾛｰﾅﾙ抗体 / モノクローナル抗体 / GroE … More Except Principal Investigator repair / 紫外線 / radiation / DDB1 / DNA損傷 / DNA damage / 修復 / 放射線 / pSC101 / chaperon / 痴呆症 / 海馬CAI / カルシウム放出 / DNA replication / 複製開始領域 / カルシュムチャネル / 遺伝子発現 / 二本鎖切断 / シナプス抑圧 / Synaptic depression / カルシウムイオン / 損傷除去修復薬 / シャペロン / てんかん / シャペロ / DNA複製開始 / 酸化的ストレス / プラスミド / シクロブタン型二量体 / 蛍光蛋白 / neuron / 脳血管性痴呆 / psc101 / fluorescent protein / double strand break / カルシウムチャンネル / カルシウム遊離 / 神経細胞 / シナプス可塑性 / Synaptic plasticity / 膜興奮性 / 修復亢進 / Synaptic transmission / DNA複製 / アストロサイト / Hippocampus CA1 / 大脳皮質 / IP3受容体 / DSB / 細胞内カルシウム / γ-H2AX / カルシウムチャネル / Calcium channel / Replication origin / DNA結合性蛋白質 / Calcium release / UV / 海馬CA1 / DNA binding protein / カリウムチャネル / oxidative stress / DNA修復 / astrocyte / シナプ可塑性 / シナプス伝達 / gamma H2AX / Plasmid Less

損傷のﾀｲﾌﾟに応じて修復を亢進させる損傷特異的人工ｴﾝﾄﾞﾇｸﾚｱｰｾﾞの応用Principal InvestigatorOngoing
- Principal Investigator
  
  杉浦重樹
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nara Medical University
DNA損傷特異抗体を損傷除去修復薬に進化させるOngoing
- Principal Investigator
  
  森俊雄
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nara Medical University
Construction of DNA damage-specific endonuclease using monoclonal antibody against DNA damagePrincipal Investigator
- Principal Investigator
  
  SUGIURA Shigeki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nara Medical University
Approaches to enhance a repair ability of UV induced DNA damage by promotion of DNA damage-recognitionPrincipal Investigator
- Principal Investigator
  
  SUGIURA Shigeki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nara Medical University
Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -
- Principal Investigator
  
  KISHIMOTO Toshifumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells
- Principal Investigator
  
  NAKAMURA Yu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Molecular coupling required for intracellular calcium release that regulates synaptic depression
- Principal Investigator
  
  KATO Nobuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Kyoto University
DNA複製におけるイニシエーター蛋白の役割Principal Investigator
- Principal Investigator
  
  杉浦重樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kanazawa University
Analysis of initiatin and its regulation in in vitro replication system of plasmid DNA
- Principal Investigator
  
  YAMAGUCHI Kazuo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Kanazawa University

All 2014 2013 2012

All Journal Article Presentation

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, T. Nishiwaki, K. Nishimura, N. Kobayashi, S. Sugiura and T. Mori.
- Journal Title
  
  Photochem. Photobiol
  
  Volume : xx Pages : 829-836
- DOI
  10.1111/php.12239
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23591626, KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-24790895, KAKENHI-PROJECT-26550042
[Journal Article] THF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014
- Author(s)
  Nukuzuma, S. Nakamichi, K. Kameoka, M. Sugiura, S. Nukuzuma, C. Tasaki, T. Takegami, T.
- Journal Title
  
  J. Med. Virol.
  
  Volume : XX Pages : 2026-2032
- DOI
  10.1002/jmv.23886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-25430119
[Journal Article] Suppressive effect oh PARP-1 inhibitor on JC virus replication in vitro2013
- Author(s)
  Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., and Takegami, T.
- Journal Title
  
  J. Med. Virol.
  
  Volume : 85 Pages : 132-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052
[Journal Article] Suppressive effect of PARP-1 inhibitor on JC virus replication in vitro2013
- Author(s)
  Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., Takegami, T.
- Journal Title
  
  J Med Virol
  
  Volume : 85 Pages : 132-137
- DOI
  10.1002/jmv.23443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052
[Journal Article] Exogenous human immunodeficiency virus-1 protein, Tat, enhances replication of JC virus efficiently in neuroblastoma cell lines2012
- Author(s)
  Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., Miyoshi, I., and Takegami, T.
- Journal Title
  
  J Med Virol
  
  Volume : 84 Pages : 555-561
- DOI
  10.1002/jmv.23239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-Cyclo-2'deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  Iwamoto, T., Brooks, P. J., Kobayashi, N., Sugiura, S., and Mori, T.
- Organizer
  International symposium on xeroderma pigmentosum and related diseases : Disorderes of DNA damage response-Bench to -bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’- cyclo- 2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  Iwamoto, T. Brooks, P. J. Kobayashi, N. Sugiura, S. and Mori, T.
- Organizer
  nternational symposium on xeroderma pigmentosum and related diseases: Disorders of DNA damage response - Bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] PARP-1阻害剤のin vitroにおけるウイルス増殖抑制効果について2013
- Author(s)
  奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、田崎隆史、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] PARP-1 阻害剤の in vitro における JC ウイルス増殖抑制効果について2013
- Author(s)
  奴久妻聡、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、田崎隆史、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] HIV-1 Tatによる神経芽細胞腫でのJCウイルス増殖促進2012
- Author(s)
  奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24651052
[Presentation] HIV-1 Tatによる神経芽細胞腫でのJCウイルス増殖促進2012
- Author(s)
  奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、竹上勉
- Organizer
  日本ウイルス学会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24651052

1. MORI Toshio (10115280)

# of Collaborated Projects : 6results

# of Collaborated Products : 3results
2. YOSHINO Hiroaki (10347560)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. NAKAMURA Yu (70291440)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
4. KISHIMOTO Toshifumi (60201456)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. KATO Nobuo (10152729)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. YAMAGUCHI Kazuo (00019879)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 織田昌幸 (20318231)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. IWAMOTO Takaaki

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. 小林信彦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. BROOKS P.J.

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
11. Brooks P. J.

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 田崎隆史

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

SUGIURA Shigeki 杉浦 重樹

Research Projects

Research Products

Co-Researchers

損傷のﾀｲﾌﾟに応じて修復を亢進させる損傷特異的人工ｴﾝﾄﾞﾇｸﾚｱｰｾﾞの応用Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA損傷特異抗体を損傷除去修復薬に進化させるOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of DNA damage-specific endonuclease using monoclonal antibody against DNA damagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Approaches to enhance a repair ability of UV induced DNA damage by promotion of DNA damage-recognitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular coupling required for intracellular calcium release that regulates synaptic depression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA複製におけるイニシエーター蛋白の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of initiatin and its regulation in in vitro replication system of plasmid DNA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] THF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressive effect oh PARP-1 inhibitor on JC virus replication in vitro2013

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effect of PARP-1 inhibitor on JC virus replication in vitro2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exogenous human immunodeficiency virus-1 protein, Tat, enhances replication of JC virus efficiently in neuroblastoma cell lines2012

Author(s)

Journal Title

SUGIURA Shigeki 杉浦重樹