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SUGIURA Shigeki  杉浦 重樹

ORCIDConnect your ORCID iD *help
Researcher Number 40179130
Other IDs
Affiliation *help 2012 – 2017 : 奈良県立医科大学, 医学部, 准教授
2007 : 奈良県立医科大学, 医学部, 准教授
2003 – 2005 : Nara Medical University, Faculty of Medicine, Associate Professor, 医学部, 助教授
2003 : 奈良県立医科学大学, 医学部, 助教授
2002 : 奈良県立医科大学, 総合研究施設部, 助教授 … More
2001 : 奈良県立医科大学, 組換えDNA実験施設, 助教授
1995 : 金沢大学, 遺伝子実験施設, 助手
1986 – 1987 : 金沢大学, 遺伝子実験施設, 助手 Less
Review Section/Research Field
Principal Investigator
Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals / Molecular biology
Except Principal Investigator
Psychiatric science / Neuroscience in general / Risk sciences of radiation and chemicals / 代謝生物化学
Keywords
Principal Investigator
修復 / DNA 損傷 / pSC101 / シクロブタン 型 ダイマー / DNA replication / Rep protein / CPD / モノクローナル 抗体 / モノクローナル抗体 / シクロブタン型ダイマー … More / シクロブタン型二量体 / plasmid / 修復亢進 / GroE / leucine zipper / DNA修復 … More
Except Principal Investigator
repair / 紫外線 / radiation / DDB1 / DNA損傷 / DNA damage / 修復 / 放射線 / pSC101 / chaperon / 痴呆症 / 海馬CAI / カルシウム放出 / DNA replication / 複製開始領域 / カルシュムチャネル / 遺伝子発現 / 二本鎖切断 / シナプス抑圧 / Synaptic depression / カルシウムイオン / 損傷除去修復薬 / シャペロン / てんかん / シャペロ / DNA複製開始 / 酸化的ストレス / プラスミド / シクロブタン型二量体 / 蛍光蛋白 / neuron / 脳血管性痴呆 / psc101 / fluorescent protein / double strand break / カルシウムチャンネル / ヌクレオチド除去修復 / カルシウム遊離 / 神経細胞 / シナプス可塑性 / Synaptic plasticity / 膜興奮性 / 修復亢進 / Synaptic transmission / DNA複製 / アストロサイト / Hippocampus CA1 / 大脳皮質 / IP3受容体 / DSB / 細胞内カルシウム / γ-H2AX / カルシウムチャネル / Calcium channel / Replication origin / DNA結合性蛋白質 / Calcium release / UV / 海馬CA1 / DNA binding protein / カリウムチャネル / oxidative stress / DNA修復 / astrocyte / シナプ可塑性 / シナプス伝達 / gamma H2AX / Plasmid Less
  • Research Projects

    (9results)
  • Research Products

    (12results)
  • Co-Researchers

    (11People)
  •  損傷のタイプに応じて修復を亢進させる損傷特異的人工エンドヌクレアーゼの応用Principal InvestigatorOngoing

    • Principal Investigator
      杉浦 重樹
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Nara Medical University
  •  DNA損傷特異抗体を損傷除去修復薬に進化させるOngoing

    • Principal Investigator
      森 俊雄
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Nara Medical University
  •  Construction of DNA damage-specific endonuclease using monoclonal antibody against DNA damagePrincipal Investigator

    • Principal Investigator
      SUGIURA Shigeki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Nara Medical University
  •  Approaches to enhance a repair ability of UV induced DNA damage by promotion of DNA damage-recognitionPrincipal Investigator

    • Principal Investigator
      SUGIURA Shigeki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Nara Medical University
  •  Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -

    • Principal Investigator
      KISHIMOTO Toshifumi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Nara Medical University
  •  Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells

    • Principal Investigator
      NAKAMURA Yu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Nara Medical University
  •  Molecular coupling required for intracellular calcium release that regulates synaptic depression

    • Principal Investigator
      KATO Nobuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      Kyoto University
  •  DNA複製におけるイニシエーター蛋白の役割Principal Investigator

    • Principal Investigator
      杉浦 重樹
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Kanazawa University
  •  Analysis of initiatin and its regulation in in vitro replication system of plasmid DNA

    • Principal Investigator
      YAMAGUCHI Kazuo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Kanazawa University

All 2016 2014 2013 2012

All Journal Article Presentation

  • [Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

    • Author(s)
      T. Iwamoto, P.J. Brooks, T. Nishiwaki, K. Nishimura, N. Kobayashi, S. Sugiura and T. Mori.
    • Journal Title

      Photochem. Photobiol.

      Volume : xx Pages : 829-836

    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23591626, KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-24790895, KAKENHI-PROJECT-26550042
  • [Journal Article] TNF-alpha stimulates efficient JC virus replication in neuroblastoma cells2014

    • Author(s)
      Nukuzuma, S. Nakamichi, K. Kameoka, M. Sugiura, S. Nukuzuma, C. Tasaki, T. Takegami, T.
    • Journal Title

      J Med Virol

      Volume : XX Pages : 2026-2032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-25430119
  • [Journal Article] Suppressive effect oh PARP-1 inhibitor on JC virus replication in vitro2013

    • Author(s)
      Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., and Takegami, T.
    • Journal Title

      J. Med. Virol.

      Volume : 85 Pages : 132-137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Journal Article] Suppressive effect of PARP-1 inhibitor on JC virus replication in vitro2013

    • Author(s)
      Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., Takegami, T.
    • Journal Title

      J Med Virol

      Volume : 85 Pages : 132-137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Journal Article] Exogenious human immunodeficiency virus-1 protein, Tat, enhances replication of JC virus efficiently in neuroblastoma cell lines2012

    • Author(s)
      Nukuzuma, S., Kameoka, M., Sugiura, S., Nakamichi, K., Nukuzuma, C., Miyoshi, I., and Takegami, T.
    • Journal Title

      J Med Virol

      Volume : 84 Pages : 555-561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Presentation] 酸化的DNA損傷サイクロプリン定量系の高感度化2016

    • Author(s)
      森 俊雄、岩本顕聡、杉浦重樹、中根裕信
    • Organizer
      第38回日本光医学・光生物学会
    • Place of Presentation
      京都
    • Year and Date
      2016-07-22
    • Data Source
      KAKENHI-PROJECT-16H02958
  • [Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-Cyclo-2'deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

    • Author(s)
      Iwamoto, T., Brooks, P. J., Kobayashi, N., Sugiura, S., and Mori, T.
    • Organizer
      International symposium on xeroderma pigmentosum and related diseases : Disorderes of DNA damage response-Bench to -bedside-
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’- cyclo- 2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

    • Author(s)
      Iwamoto, T. Brooks, P. J. Kobayashi, N. Sugiura, S. and Mori, T.
    • Organizer
      nternational symposium on xeroderma pigmentosum and related diseases: Disorders of DNA damage response - Bench to bedside-
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Presentation] PARP-1阻害剤のin vitroにおけるウイルス増殖抑制効果について2013

    • Author(s)
      奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、田崎隆史、竹上勉
    • Organizer
      日本ウイルス学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Presentation] PARP-1 阻害剤の in vitro における JC ウイルス増殖抑制効果について2013

    • Author(s)
      奴久妻聡、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、田崎隆史、竹上勉
    • Organizer
      日本ウイルス学会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Presentation] HIV-1 Tatによる神経芽細胞腫でのJCウイルス増殖促進2012

    • Author(s)
      奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、竹上勉
    • Organizer
      日本ウイルス学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24651052
  • [Presentation] HIV-1 Tatによる神経芽細胞腫でのJCウイルス増殖促進2012

    • Author(s)
      奴久妻聡一、亀岡正典、杉浦重樹、中道一生、奴久妻智代子、竹上勉
    • Organizer
      日本ウイルス学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-24651052
  • 1.  MORI Toshio (10115280)
    # of Collaborated Projects : 6results
    # of Collaborated Products : 4results
  • 2.  YOSHINO Hiroaki (10347560)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 3.  NAKAMURA Yu (70291440)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 4.  KISHIMOTO Toshifumi (60201456)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 5.  KATO Nobuo (10152729)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 6.  YAMAGUCHI Kazuo (00019879)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 7.  織田 昌幸 (20318231)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 8.  IWAMOTO Takaaki
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 9.  KOBAYASHI Nobuhiko
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 10.  TASAKI Takafumi
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 11.  BROOKS P.J.
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results

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