Takamatsu Nobuhiko 高松信彦

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TAKAMATSU Nobuhiko 高松信彦

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Researcher Number	40206876
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2022: 北里大学, 理学部, 教授 2010 – 2012: 北里大学, 理学部, 教授 2005 – 2006: 北里大学, 理学部, 助教授 2000 – 2001: 北里大学, 理学部, 助教授 1997: Kitasato University, Faculty of Science, Associate Professor, 理学部, 助教授 … More 1996: 北里大学, 理学部, 講師 1994: Kitasato Univ.School of Sci.Lecturer, 理学部, 講師 1992 – 1993: 北里大学, 衛生学部, 講師 1989 – 1990: 北里大学, 衛生学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / 基礎ゲノム科学 / 遺伝 / Applied biochemistry Except Principal Investigator Fisheries chemistry / General fisheries / Laboratory animal science
Keywords	Principal Investigator 冬眠 / 肝臓 / transcriptional regulation / HNF-4 / HNF-1 / 転写調節 / 転写制御 / 低体温 / Per2遺伝子 / AMPK … More / 中途覚醒 / 体温変動 / HSF1 / Per2 / 末梢時計 / 概日リズム / liver / hibernation / chromatin immunoprecipitation / histone modification / gene expression / USF / メチル化 / CpG配列 / クロマチン免疫沈降法 / ヒストン修飾 / クロマチン免疫沈降 / ピストン修飾 / 遺伝子発現 / tree squirrel / chipmunk / pseudogene / gene structure / mammalian hibernation / 哺乳動物 / プロモーター / タイワンリス / シマリス / 偽遺伝子 / 遺伝子構造 / プロテオーム / 概念リズム / 転写因子 / 概年リズム … More Except Principal Investigator HMGbox / SRY / アミノ酸配列 / cDNA / レクチン / Gene / Amino acid sequence / Antibacterial and antitumor proteins / Mitogens / Lectins / Protease inhibitors / Peptide toxins / Marine bioactive proteins / 遺伝子 / 抗菌・抗腫瘍タンパク質 / 免疫賦活タンパク質 / プロテアーゼインヒビター / ペプチド毒 / 海産生理活性タンパク質 / Gonad / Leucine zipper / Spermatogenesis / Rainbow trout / SOX / PCR / SRYボックス / 魚類 / 性決定 / 大腸菌発現ベクター / 抗体 / 制限酵素地図 / cDNAクローニング / SOX-LZ / ロイシン・ジッパー / SRY様HMGbox / HMG box / 生殖巣 / 精子形成 / 転写因子 / 2量体形成 / ロイシンジッパー / Sinularia / Aplysia juliana / Antibacterial / Sequence / Barnacle / Hemagglutinin / Lectin / 一次構造 / 抗腫瘍性 / ヘマグルチュン / <Aplysia>___ー <juliana>___ー / <Sinularia>___ー. sp / シヌラリア / アマクサアメフラシ / 抗菌性 / 配列分析 / フジツボ / ヘマグルチニン / ENU / 炎症 / マウス遺伝学 / リン酸化 / シグナル伝達 / 関節炎 / 自己炎症性症候群 / 病態モデル / 実験動物学 / 疾患モデル Less

Analysis of the relationship between the peripheral circadian clock and hibernation in a hibernating mammalPrincipal Investigator
- Principal Investigator
  
  Takamatsu Nobuhiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Kitasato University
Analysis of the inflammatory mechanisms caused by the Ali18 mutation in molecular and cellular levels
- Principal Investigator
  
  ABE Koichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University
Analysis of hibernation-associated gene regulation in chipmunkPrincipal Investigator
- Principal Investigator
  
  TAKAMATSU Nobuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kitasato University
Hibernation-associated gene expression regulated by epigenetic modificationsPrincipal Investigator
- Principal Investigator
  
  TAKAMATSU Nobuhiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Kitasato University
Comparative analysis of hibernation-specific genes between hibernating and nonhibernating mammalsPrincipal Investigator
- Principal Investigator
  
  TAKAMATSU Nobuhiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  遺伝
- Research Institution
  Kitasato University
Screening, structure and usefulness of marine bioactive proteins
- Principal Investigator
  
  SHIOMI Kazuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Tokyo University of Fisheries
Isolation of sex determination-related genes in rainbow trout
- Principal Investigator
  
  SHIBA Tadayoshi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General fisheries
- Research Institution
  Kitasato University
Purification, Structure Determination, and Gene Cloning For Bioactive Biopolymers of Marine Invertebrates
- Principal Investigator
  
  KAMIYA Hisao
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  School of Fisheries Sciences, Kitasato University

All 2023 2022 2021 2020 2013 2012 2011 2010 2007 2006

All Journal Article Presentation Book

[Book] シマリスの冬眠の分子生物学的研究2023
- Author(s)
  塚本大輔，高松信彦
- Publisher
  北海道大学低温科学研究所
- Data Source
  KAKENHI-PROJECT-20K06746
[Book] 冬眠動物シマリスの冬眠に伴う遺伝子発現制御機構2020
- Author(s)
  塚本大輔，高松信彦
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20K06746
[Journal Article] Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation2023
- Author(s)
  Takamatsu Nobuhiko、Shirahata Yuiho、Seki Kota、Nakamaru Erina、Ito Michihiko、Tsukamoto Daisuke
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 4 Pages: 104576-104576
- DOI
  10.1016/j.jbc.2023.104576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06447, KAKENHI-PROJECT-20K06746
[Journal Article] Gene expression regulation during hibernation using body temperature fluctuations in the mammalian hibernator chipmunk2021
- Author(s)
  塚本大輔、高松信彦
- Journal Title
  
  生化学
  
  Volume: 93 Issue: 6 Pages: 830-834
- DOI
  10.14952/SEIKAGAKU.2021.930830
- NAID
  40022783954
- ISSN
  0037-1017
- Year and Date
  2021-12-25
- Language
  Japanese
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06447, KAKENHI-PROJECT-20K06746
[Journal Article] Identification of bovine hibernation-specific protein complex and evidence of its regulation in fasting and aging2013
- Author(s)
  Fujita, S., Okamoto, R., Taniguchi, M., Ban-Tokuda, T., Konishi, K., Goto, I., Yamamoto, Y., Sugimoto, K., Takamatsu, N., Nakamura, M., Shiraki, K., Buechler, C., Ito, M.
- Journal Title
  
  J. Biochem
  
  Volume: 153巻 Issue: 5 Pages: 453-461
- DOI
  10.1093/jb/mvt008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580107, KAKENHI-PROJECT-24591113
[Journal Article] USF is involved in the transcriptional regulation of the chipmunk HP-25 gene.2007
- Author(s)
  Tsukamoto, D., Fujii, G., Kondo, N., Ito, M., Shiba, T., Takamatsu, N.
- Journal Title
  
  Gene (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510160
[Journal Article] CpG methylation at the USF-binding site is important for the liver-specific transcription of the chipmunk HP-27 gene.2006
- Author(s)
  Fujii, G., Nakamura, Y., Tsukamoto, D., Ito, M., Shiba, T., Takamatsu, N.
- Journal Title
  
  Biochem.J. 395
  
  Pages: 203-209
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510160
[Presentation] 冬眠哺乳動物シマリスの miR-182-5p による FOXO1 の発現制御と FOXO1 による GADD45A の転写制御の解析2022
- Author(s)
  白畠由比穂, 高松信彦
- Organizer
  第4回冬眠休眠研究会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] シマリス冬眠の低体温に伴う Rbm3 遺伝子の発現制御機構と機能の解析2022
- Author(s)
  塚本大輔，坂部寧々，関皓太，白畠由比穂，中丸絵莉奈，伊藤道彦，高松信彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠哺乳動物シマリスの肝臓における CREB1 の機能解析2022
- Author(s)
  中丸絵莉奈, 高松信彦
- Organizer
  第4回冬眠休眠研究会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠哺乳動物シマリスの miR-182-5p による時計遺伝子 CLOCK の発現制御の解析2022
- Author(s)
  関皓太, 高松信彦
- Organizer
  第4回冬眠休眠研究会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] シマリス肝臓における冬眠期の体温変動に伴った発現変動遺伝子の網羅的解析2022
- Author(s)
  塚本大輔, 高松信彦
- Organizer
  第4回冬眠休眠研究会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠に伴うストレス応答遺伝子 GADD45A の FOXO1 による転写活性化機構の解明2022
- Author(s)
  白畠由比穂，関皓太，中丸絵莉奈，岡村瑠美，塚本大輔，伊藤道彦，高松信彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠哺乳動物シマリスの肝臓における CREB1 バリアントの発現及び機能解析2022
- Author(s)
  中丸絵莉奈，安達めぐみ，白畠由比穂，関皓太，塚本大輔，伊藤道彦，高松信彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠哺乳動物シマリスの肝臓の末梢時計の発現制御の解析2022
- Author(s)
  関皓太，白畠由比穂，中丸絵莉奈，塚本大輔，伊藤道彦，高松信彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠哺乳動物シマリスのmiR-182-5pによるFOXO1の発現抑制とFOXO1によるGADD45Aの転写制御の解析2021
- Author(s)
  白畠由比穂，関皓太，岡村瑠美，塚本大輔，伊藤道彦，高松信彦
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] 冬眠哺乳動物シマリスのmiR-182-5pによる時計遺伝子CLOCKの発現制御の解析2021
- Author(s)
  関皓太，白畠由比穂，塚本大輔，伊藤道彦，高松信彦
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] シマリスの肝臓における体温変動を利用した冬眠に伴う遺伝子の発現制御機構2020
- Author(s)
  塚本大輔，伊藤道彦，高松信彦
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06746
[Presentation] シマリスHSP70遺伝子のHSF-2による冬眠に伴う転写調節機構の解析2012
- Author(s)
  飯尾浩子,伊藤道彦,高松信彦
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22580107
[Presentation] Hibernation-associated transcriptional regulation of the chipmunk HP-25 gene2011
- Author(s)
  菅井玲,綿引陽子,廣瀬真一,伊藤道彦,高松信彦
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22580107
[Presentation] 哺乳動物の冬眠にともなう肝臓のプロテオーム変動の解析2010
- Author(s)
  松澤彰彦,川島祐介,斎藤達也,大橋和也,高松信彦,小寺義男
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22580107

1. ITO Michihiko (90240994)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. KAMIYA Hisao (80011964)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SHIBA Tadayoshi (80187385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MURAMOTO Koji (90157800)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ABE Koichiro (90294123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIMURA Minoru (10146706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KODERA Yoshio (60265733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. KANDA Hiromi (80234160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIOMI Kazuo (90111690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Yuzuru (40107412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HORI Kanji (50116662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 塚本大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takamatsu Nobuhiko 高松 信彦

TAKAMATSU Nobuhiko 高松 信彦

Research Projects

Research Products

Co-Researchers

Analysis of the relationship between the peripheral circadian clock and hibernation in a hibernating mammalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the inflammatory mechanisms caused by the Ali18 mutation in molecular and cellular levels

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of hibernation-associated gene regulation in chipmunkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hibernation-associated gene expression regulated by epigenetic modificationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comparative analysis of hibernation-specific genes between hibernating and nonhibernating mammalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening, structure and usefulness of marine bioactive proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of sex determination-related genes in rainbow trout

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Purification, Structure Determination, and Gene Cloning For Bioactive Biopolymers of Marine Invertebrates

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] シマリスの冬眠の分子生物学的研究2023

Author(s)

Publisher

Data Source

[Book] 冬眠動物シマリスの冬眠に伴う遺伝子発現制御機構2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene expression regulation during hibernation using body temperature fluctuations in the mammalian hibernator chipmunk2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Identification of bovine hibernation-specific protein complex and evidence of its regulation in fasting and aging2013

Author(s)

Journal Title

DOI

Takamatsu Nobuhiko 高松信彦

TAKAMATSU Nobuhiko 高松信彦