NAGASE Takahide 長瀬隆英

… Alternative Names

長瀬隆英ナガセタカヒデ

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Researcher Number	40208004
Other IDs
Affiliation (based on the past Project Information) *help	2003 – 2021: The Univ. of Tokyo, Faculty of Medicine, Professor, 医学部附属病院, 教授 2014: 東京大学, 大学病院, 教授 2010: 東京大学, 病院, 教授 2001 – 2002: The Univ. of Tokyo, Faculty of Medicine, Lecturer, 医学部附属病院, 講師 1999 – 2001: The Univ. of Tokyo, Faculty of Medicine Lecturer, 医学部・附属病院, 講師 1998: 東京大学, 医学部・附属病院, 助手 1994: 東京大学, 医学部(病), 教務職員
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Basic Section 52010:General internal medicine-related / Respiratory organ internal medicine / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator PAF / ARDS / ノックアウトマウス / Transgenic mouse / Knockout mouse / トランスジェニックマウス / 肺線維症 / 抗菌ペプチド / LPS / CGRP … More / 血小板活性化因子 / エイコサノイド / 呼吸器内科 / 呼吸器内科学 / 脂質性メディエーター / 転写コアクチベーター / 肺炎症 / Antimicrobial peptides / Lipid mediators / カルシトニン遺伝子関連ペプチド / エンドトキシン / 急性呼吸窮迫症候群 / トランスジェニツクマウス / knockout mice / transgenic mice / bleomycin / pulmonary fibrosis / 血小板治性化因子 / ブレオマイシン / プレオマイシン / 間質性肺炎 / siRNA / ＣＯＰＤ / 生理活性ペプチド / 転写因子 / 脂質メディエーター / 呼吸器感染症 / 非閉塞性肺疾患癌 / 感染防御 / マウス / デフェンシン / COX-inhibitor / steroid / mouse / defensin / 肺組織抵抗 / 接着分子 / 気管支喘息 … More Except Principal Investigator COPD / Glutathione S-transferase P1 / 気管支喘息 / CGRP / 肺線維症 / アドレノメデュリン / 傾眠 / 終末期 / 胃運動 / 虚血性心疾患 / 慢性心不全 / 加齢 / 心房細動 / 心不全 / 睡眠時無呼吸 / 呼吸リズム / adrenomedullin / pulmonary fibrosis / bronchial asthma / 気道過敏症 / 遺伝子改変マウス / apoptosis / Adenovirus vector / chronic tabacco exposure / klotho gene / Gene Therapy / グルタチオンSトランスフェラーゼ / 肺気腫 / 慢性閉塞性肺疾患(COPD) / アポトーシス / アデノウイルスベクター / 慢性喫煙 / Klotho遺伝子 / 遺伝子治療 / Knockout mouse / Airway heperresponsiveness / Bronchial asthma / 気道過敏 / ノックアウトマウス / シックアウトマウス / 気道過敏性 / EGFR / ブレオマイシン / マウス / EGFRファミリー / プロテオグリカン / 閉塞性肺疾患 / 全身性炎症 / 身体非活動性 / 運動療法 / 電気刺激 / 骨格筋収縮 / 全身炎症 / myostatin / 筋収縮 / 収縮 / 骨格筋 / 慢性閉塞性肺疾患 / ミオスタチン / IL-6 / 身体活動性 / ミオカイン Less

Establishment and application of the physiological biomarkers in older people at the end-of-life
- Principal Investigator
  
  Yasuhiro Yamaguchi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Jichi Medical University
  The University of Tokyo
The investigation of respiratory diseases and development of novel therapeutics using up-to-date molecular and cellular techniquesPrincipal Investigator
- Principal Investigator
  
  NAGASE TAKAHIDE
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
The investigation of genes related to refractory respiratory diseases and development of novel therapeuticsPrincipal Investigator
- Principal Investigator
  
  NAGASE TAKAHIDE
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis
- Principal Investigator
  
  JO Taisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Pysical Inactivities and systemic inflammation. Investigation of anti-inflammatory effects of exercise in patiens with chronic respiratory disease
- Principal Investigator
  
  KUROSAWA Hajime
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tohoku University
Investigation about the effect of Adrenomedullin on pulmonary function and development of emphysema of old mice
- Principal Investigator
  
  YAMAMOTO Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
The investigation of molecular mechanisms underlying refractory respiratory diseases and exploration of novel therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Pathophysiological role of Adrenomedullin on the etiology of bronchial asthma and pulmonary fibrosis
- Principal Investigator
  
  YAMAMOTO Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
未知の抗菌ペプチドの探索および炎症性肺疾患発症制御の可能性Principal Investigator
- Principal Investigator
  
  長瀬隆英
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Exploration of therapeutic targets for refractory inflammatory lung diseases and development of novel therapeutic strategiesPrincipal Investigator
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Experimental approach for gene therapy of pulmonary emphysema focusing on Klotho gene and GSTP1 gene
- Principal Investigator
  
  TERAMOTO Shinji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Roles of CGRP family peptides in the molecular mechanisms underlying bronchial asthma: the development of novel therapeutic approach
- Principal Investigator
  
  YAMAMOTO Hiroshi, 大賀栄次郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
炎症性肺疾患発症分子機構における抗菌ペプチドdefensinの意義Principal Investigator
- Principal Investigator
  
  長瀬隆英
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying ARDS and development of novel therapeutic strategies using genetically-engineered micePrincipal Investigator
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Novel therapeutic straetgies to inflammatory lung diseases using genetically-engineering technique : roles of eicosanoids and PAFPrincipal Investigator
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Roles of PAF in bleomycin-induced pneumonia in knockout and transgenic micePrincipal Investigator
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
気管支喘息発症メカニズムにおけるCGRP及び接着分子の関与Principal Investigator
- Principal Investigator
  
  長瀬隆英
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo

[Book] Roles of lipid mediators in acute lung injury and pulmonary fibrosis. In : Physiologic basis of respiratory disease. (Hamid Q, Shannon J, Martin J, editors.)2005
- Author(s)
  Nagase T
- Publisher
  BC Decker, Hamilton, Ontario, CANADA
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Active mTOR in Lung Epithelium Promotes Epithelial-Mesenchymal Transition and Enhances Lung Fibrosis2020
- Author(s)
  Saito M, Mitani A, Ishimori T, Miyashita N, Isago H, Mikami Y, Noguchi S, Tarui M, Nagase T.
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: - Issue: 6 Pages: 699-708
- DOI
  10.1165/rcmb.2019-0255oc
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17629, KAKENHI-PROJECT-17K15009, KAKENHI-PROJECT-16H02653
[Journal Article] Dual EGFR and ABL Tyrosine Kinase Inhibitor Treatment in a Patient with Concomitant EGFR-Mutated Lung Adenocarcinoma and BCR-ABL1-Positive CML2020
- Author(s)
  Kousuke Watanabe, Hidenori Kage, Saki Nagoshi, Kazuhiro Toyama, Yoshiyuki Ohno, Aya Shinozaki-Ushiku, Kumi Nakazaki, Hiroshi Suzuki, Mineo Kurokawa, Takahide Nagase
- Journal Title
  
  Case Rep Oncol Med
  
  Volume: 2020 Pages: 1-6
- DOI
  10.1155/2020/4201727
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08622, KAKENHI-PROJECT-16H02653
[Journal Article] FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms2020
- Author(s)
  Miyashita Naoya、Horie Masafumi、Suzuki Hiroshi I.、Saito Minako、Mikami Yu、Okuda Kenichi、Boucher Richard C.、Suzukawa Maho、Hebisawa Akira、Saito Akira、Nagase Takahide
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 63 Issue: 6 Pages: 831-842
- DOI
  10.1165/rcmb.2019-0396oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-18K08170
[Journal Article] Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia2020
- Author(s)
  Okuda K, , Nagase T, Boucher RC. et al
- Journal Title
  
  American Journal of Respiratory and Critical Care Medicine
  
  Volume: - Issue: 10 Pages: 1275-1289
- DOI
  10.1164/rccm.202008-3198oc
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development2020
- Author(s)
  Isago Hideaki、Mitani Akihisa、Mikami Yu、Horie Masafumi、Urushiyama Hirokazu、Hamamoto Ryuji、Terasaki Yasuhiro、Nagase Takahide
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 62 Issue: 2 Pages: 256-266
- DOI
  10.1165/rcmb.2019-0218oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17628, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-16K09575, KAKENHI-PROJECT-17K09630
[Journal Article] Integrin α11 in non-small cell lung cancer is associated with tumor progression and postoperative recurrence.2020
- Author(s)
  Ando T, Kage H, Matsumoto Y, Zokumasu K, Yotsumoto T, Maemura K, Amano Y, Watanabe K, Nakajima J, Nagase T, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 1 Pages: 200-208
- DOI
  10.1111/cas.14257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-18K15266
[Journal Article] Inhaled corticosteroid withdrawal may improve outcomes in elderly patients with COPD exacerbation: a nationwide database study2020
- Author(s)
  Jo Taisuke、Yasunaga Hideo、Yamauchi Yasuhiro、Mitani Akihisa、Hiraishi Yoshihisa、Hasegawa Wakae、Sakamoto Yukiyo、Matsui Hiroki、Fushimi Kiyohide、Nagase Takahide
- Journal Title
  
  ERJ Open Research
  
  Volume: 6 Issue: 1 Pages: 00246-2019
- DOI
  10.1183/23120541.00246-2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-16H02653
[Journal Article] Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways.2019
- Author(s)
  Okuda K, Chen G, Subramani DB, Wolf M, Gilmore RC, Kato T, Radicioni G, Kesimer M, Chua M, Dang H, Livraghi-Butrico A, Ehre C, Doerschuk CM, Randell SH, Matsui H, Nagase T, O'Neal WK, Boucher RC.
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 199 Issue: 6 Pages: 715-727
- DOI
  10.1164/rccm.201804-0734oc
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] Activation through toll-like receptor 2 on group 2 innate lymphoid cells can induce asthmatic characteristics.2019
- Author(s)
  Ishii T, Muroi M, Horiguchi K, Tanamoto KI, Nagase T, Yamashita N.
- Journal Title
  
  Clin Exp Allergy.
  
  Volume: 49 Issue: 12 Pages: 1624-1632
- DOI
  10.1111/cea.13490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing2019
- Author(s)
  Kage Hidenori、Kohsaka Shinji、Shinozaki‐Ushiku Aya、Hiraishi Yoshihisa、Sato Jiro、Nagayama Kazuhiro、Ushiku Tetsuo、Takai Daiya、Nakajima Jun、Miyagawa Kiyoshi、Aburatani Hiroyuki、Mano Hiroyuki、Nagase Takahide
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 8 Pages: 2652-2657
- DOI
  10.1111/cas.14112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-17K10778
[Journal Article] Reference value for expiratory time constant calculated from the maximal expiratory flow-volume curve.2019
- Author(s)
  Ikeda T, Yamauchi Y, Uchida K, Oba K, Nagase T, Yamada Y.
- Journal Title
  
  BMC Pulm Med.
  
  Volume: 19 Issue: 1 Pages: 208-208
- DOI
  10.1186/s12890-019-0976-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-19H03907, KAKENHI-PROJECT-18H02896
[Journal Article] CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts2019
- Author(s)
  Takeshima Hideyuki、Horie Masafumi、Mikami Yu、Makita Kosuke、Miyashita Naoya、Matsuzaki Hirotaka、Noguchi Satoshi、Urushiyama Hirokazu、Hiraishi Yoshihisa、Mitani Akihisa、Borok Zea、Nagase Takahide、Yamauchi Yasuhiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 68 Issue: 1 Pages: 101-109
- DOI
  10.1016/j.alit.2018.08.005
- NAID
  130007557853
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-17K16042, KAKENHI-PROJECT-18K15945, KAKENHI-PROJECT-17K15009
[Journal Article] Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice.2019
- Author(s)
  Urushiyama H, Terasaki Y, Nagasaka S, Kokuho N, Endo Y, Terasaki M, Kunugi S, Makita K, Isago H, Hosoki K, Souma K, Ishii T, Matsuzaki H, Hiraishi Y, Mikami Y, Noguchi S, Tamiya H, Mitani A, Yamauchi Y, Shimizu A, Nagase T.
- Journal Title
  
  J Cell Mol Med.
  
  Volume: 3 Issue: 5 Pages: 1-9
- DOI
  10.1111/jcmm.14255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09630, KAKENHI-PROJECT-18K15918, KAKENHI-PROJECT-17K16042, KAKENHI-PROJECT-18K15946, KAKENHI-PROJECT-19K17627, KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-17K15009
[Journal Article] Polysomnographic features of low arousal threshold in overlap syndrome involving obstructive sleep apnea and chronic obstructive pulmonary disease2019
- Author(s)
  Yamaguchi Y, Shiota S, Kusunoki Y, Hamaya H, Ishii M, Kodama Y, Akishita M, Kida K, Takahashi K, Nagase T, Fukuchi Y
- Journal Title
  
  Sleep Breath.
  
  Volume: 印刷中 Issue: 4 Pages: 1095-1100
- DOI
  10.1007/s11325-019-01786-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07440
[Journal Article] Early stage non-small cell lung cancer patients need brain imaging regardless of symptoms.2018
- Author(s)
  Ando T, Kage H, Saito M, Amano Y, Goto Y, Nakajima J, Nagase T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 23 Issue: 4 Pages: 641-646
- DOI
  10.1007/s10147-018-1254-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas.2018
- Author(s)
  Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, Brunnstrom H, Lindskog C, Elfving H, Micke P, Saito A, Nagase T.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 13(11) Issue: 11 Pages: 1676-1691
- DOI
  10.1016/j.jtho.2018.07.096
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-16H02653
[Journal Article] Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma.2018
- Author(s)
  Maemura K, Watanabe K, Ando T, Hiyama N, Sakatani T, Amano Y, Kage H, Nakajima J, Yatomi Y, Nagase T, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Issue: 10 Pages: 3326-3335
- DOI
  10.1111/cas.13742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer.2018
- Author(s)
  Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnstrom H, Micke P, Nagase T, Saito A.
- Journal Title
  
  J Pathol
  
  Volume: 246(2) Issue: 2 Pages: 154-165
- DOI
  10.1002/path.5109
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08170, KAKENHI-PROJECT-16H02653
[Journal Article] TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts.2018
- Author(s)
  Horie M, Miyashita N, Mikami Y, Noguchi S, Yamauchi Y, Suzukawa M, Fukami T, Ohta K, Asano Y, Sato S, Yamaguchi Y, Ohshima M, Suzuki HI, Saito A, Nagase T.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 314 Issue: 1 Pages: L177-L191
- DOI
  10.1152/ajplung.00193.2017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-16K11843, KAKENHI-PROJECT-17K09629
[Journal Article] Mean platelet volume and lymphocyte-to-monocyte ratio are associated with shorter progression-free survival in EGFR-mutant lung adenocarcinoma treated by EGFR tyrosine kinase inhibitor.2018
- Author(s)
  Watanabe K, Yasumoto A, Amano Y, Kage H, Goto Y, Yatomi Y, Takai D, Nagase T.
- Journal Title
  
  PLoS One.
  
  Volume: - Issue: 9 Pages: e0203625-e0203625
- DOI
  10.1371/journal.pone.0203625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] Association between dementia and discharge status in patients hospitalized with pneumonia.2017
- Author(s)
  Jo T, Yasunaga H, Sasabuchi Y, Michihata N, Morita K, Yamauchi Y, Hasegawa W, Takeshima H, Sakamoto Y, Matsui H, Fushimi K, Nagase T.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 128 Issue: 1 Pages: 128-128
- DOI
  10.1186/s12890-017-0473-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC2017
- Author(s)
  Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T.
- Journal Title
  
  Mol Cancer Res.
  
  Volume: 15 Issue: 10 Pages: 1354-1365
- DOI
  10.1158/1541-7786.mcr-17-0191
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11843, KAKENHI-PROJECT-17K16042, KAKENHI-PROJECT-17K18366, KAKENHI-PROJECT-16H02653
[Journal Article] Orchestrating Role of Apoptosis Inhibitor of Macrophage in the Resolution of Acute Lung Injury.2017
- Author(s)
  Kimura H, Suzuki M, Konno S, Shindou H, Shimizu T, Nagase T, Miyazaki T, Nishimura M.
- Journal Title
  
  J Immunol.
  
  Volume: 199 Issue: 11 Pages: 3870-3882
- DOI
  10.4049/jimmunol.1601798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts.2017
- Author(s)
  Noguchi S, Saito A, Mikami Y, Urushiyama H, Horie M, Matsuzaki H, Takeshima H, Makita K, Miyashita N, Mitani A, Jo T, Yamauchi Y, Terasaki Y, Nagase T.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 42595-42595
- DOI
  10.1038/srep42595
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-15K19172, KAKENHI-PROJECT-15K19414, KAKENHI-PROJECT-17K09630
[Journal Article] IFN Regulatory Factor 3 Potentiates Emphysematous Aggravation by Lipopolysaccharide.2017
- Author(s)
  Ishii T, Hosoki K, Nikura Y, Yamashita N, Nagase T, Yamashita N.
- Journal Title
  
  J Immunol.
  
  Volume: 198 Issue: 9 Pages: 3637-3649
- DOI
  10.4049/jimmunol.1601069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02653
[Journal Article] Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD.2016
- Author(s)
  Yamauchi Y, Yasunaga H, Hasegawa W, Sakamoto Y, Takeshima H, Jo T, Matsui H, Fushimi K, Nagase T
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 11 Pages: 1403-1411
- DOI
  10.2147/copd.s107985
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K09211
[Journal Article] Development of an In Vitro Assay to Evaluate Contractile Function of Mesenchymal Cells that Underwent Epithelial-Mesenchymal Transition.2016
- Author(s)
  Mikami Y, Matsuzaki H, Takeshima H, Makita K, Yamauchi Y, Nagase T.
- Journal Title
  
  J Vis Exp
  
  Volume: 112 Issue: 112
- DOI
  10.3791/53974
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K19172
[Journal Article] Mortality associated with bone fractures in COPD patients2016
- Author(s)
  Yamauchi Y, Yasunaga H, Sakamoto Y, Hasegawa W, Takeshima H, Urushiyama H, Jo T, Matsui H, Fushimi K, Nagase T.
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 11 Pages: 2335-2340
- DOI
  10.2147/copd.s112142
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K09211
[Journal Article] YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.2016
- Author(s)
  Horie M, Saito A, Ohshima M, Suzuki HI, Nagase T.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 12 Pages: 1755-1766
- DOI
  10.1111/cas.13078
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-16K18437
[Journal Article] Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.2016
- Author(s)
  Horie M, Yamaguchi Y, Saito A, Nagase T, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Forrest AR, Hayashizaki Y, Suzutani T, Kappert K, Micke P, Ohshima M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep33666
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-15K15768, KAKENHI-PROJECT-16K11843
[Journal Article] Histone methylation-mediated silencing of miR-139 enhances invasion of non-small-cell lung cancer2015
- Author(s)
  Kousuke Watanabe, Yosuke Amano, Rie Ishikawa, Mitsuhiro Sunohara, Hidenori Kage, Junji Ichinose, Atsushi Sano, Jun Nakajima, Masashi Fukayama, Yutaka Yatomi, Takahide Nagase, Nobuya Ohishi and Daiya Takai
- Journal Title
  
  Cancer Medicine
  
  Volume: 4 Issue: 10 Pages: 1573-82
- DOI
  10.1002/cam4.505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20917, KAKENHI-PROJECT-23249045
[Journal Article] Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.2015
- Author(s)
  MatsuzakiH, Mikami Y, Yamauchi Y ,et al.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 10 Pages: 10-10
- DOI
  10.1371/journal.pone.0141746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
[Journal Article] Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM32015
- Author(s)
  Amano Y, Ishikawa R, Sakatani T, Ichinose J, Sunohara M, Watanabe K, Kage H, Nakajima J, Nagase T, Ohishi N, Takai D
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 13 Issue: 3 Pages: 457-60
- DOI
  10.1016/j.bbrc.2015.01.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830098, KAKENHI-PROJECT-23249045
[Journal Article] Factors that predict in-hospital mortality in eosinophilic granulomatosis with polyangiitis.2015
- Author(s)
  Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, Fushimi K, Takami K, Nagase T
- Journal Title
  
  Allergy.
  
  Volume: 70 Issue: 5 Pages: 585-90
- DOI
  10.1111/all.12597
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045
[Journal Article] Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.2015
- Author(s)
  Urushiyama H, Terasaki Y, Nagasaka S, Terasaki M, Kunugi S, Nagase T, Fukuda Y, Shimizu A.
- Journal Title
  
  Lab Invest
  
  Volume: 95 Issue: 8 Pages: 872-885
- DOI
  10.1038/labinvest.2015.66
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461203, KAKENHI-PROJECT-26461204, KAKENHI-PROJECT-15K19434, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-25461175
[Journal Article] Hippo and TGF-β interplay in the lung field2015
- Author(s)
  Saito A, Nagase T
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 309(8) Issue: 8 Pages: L756-L767
- DOI
  10.1152/ajplung.00238.2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-23249045
[Journal Article] Ovary-dependent emphysema augmentation and osteopontin induction in adult female mice.2015
- Author(s)
  Niikura Y, Ishii T, Hosoki K, Nagase T, Yamashita N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 461 Issue: 4 Pages: 642-7
- DOI
  10.1016/j.bbrc.2015.04.081
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-25460660
[Journal Article] Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.2015
- Author(s)
  Yamauchi Y, Yasunaga H, Matsui H, et al.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 15 Issue: 1 Pages: 69-69
- DOI
  10.1186/s12890-015-0064-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
[Journal Article] Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential.2015
- Author(s)
  Yamato A, Soda M, Ueno T, Kojima S, Sonehara K, Kawazu M, Sai E, Yamashita Y, Nagase T, Mano H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 9 Pages: 1137-42
- DOI
  10.1111/cas.12726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430106, KAKENHI-PROJECT-26461155, KAKENHI-PROJECT-23249045
[Journal Article] Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.2015
- Author(s)
  Yamauchi Y, Yasunaga H, Matsui H, et al.
- Journal Title
  
  Respirology
  
  Volume: 20 Issue: 6 Pages: 940-946
- DOI
  10.1111/resp.12556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
[Journal Article] Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.2014
- Author(s)
  Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: 1-21
- DOI
  10.1371/journal.pone.0114791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24591125
[Journal Article] Novel swine model of transfusion-related acute lung injury.2014
- Author(s)
  Okazaki H, Ishikawa O, Iijima T, Kohira T, Teranishi M, Kawasaki S, Saito A, Mikami Y, Sugiura A, Hashimoto S, Shimada E, Uchikawa M, Matsuhashi M, Tsuno NH, Tanaka M, Kiyokawa N, Fujimoto J, Nagase T, Tadokoro K, Takahashi K.
- Journal Title
  
  Transfusion.
  
  Volume: 54 Issue: 12 Pages: 3097-3107
- DOI
  10.1111/trf.12766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-26461185
[Journal Article] Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.2014
- Author(s)
  6.Horie M, Saito A, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, Suzuki HI, Kohyama T, Nagase T.
- Journal Title
  
  BMC Cancer.
  
  Volume: 14 Issue: 1 Pages: 580-580
- DOI
  10.1186/1471-2407-14-580
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-25460137, KAKENHI-PROJECT-26461185
[Journal Article] Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer.2014
- Author(s)
  Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 9 Pages: 1135-1141
- DOI
  10.1111/cas.12472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24791455, KAKENHI-PROJECT-25830098
[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.2014
- Author(s)
  5.Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Nakajima J, Takizawa H, Nagase T, Kohyama T.
- Journal Title
  
  Exp Lung Res.
  
  Volume: 40 Issue: 5 Pages: 222-36
- DOI
  10.3109/01902148.2014.900155
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-23790899, KAKENHI-PROJECT-24591154, KAKENHI-PROJECT-26461185
[Journal Article] Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2.2014
- Author(s)
  4.Tarui M, Shindou H, Kumagai K, Morimoto R, Harayama T, Hashidate T, Kojima H, Okabe T, Nagano T, Nagase T, Shimizu T.
- Journal Title
  
  J Lipid Res.
  
  Volume: 55 Pages: 1386-96
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045
[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor2014
- Author(s)
  Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Takizawa H, Nagase T, Kohyama T
- Journal Title
  
  Experimental Lung Research
  
  Volume: 未確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591139
[Journal Article] An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.2014
- Author(s)
  3.Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 20 Issue: 17 Pages: 4660-72
- DOI
  10.1158/1078-0432.ccr-13-3328
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-26461185
[Journal Article] MxA transcripts with distinct first exons and modulation of gene expression levels by single-nucleotide polymorphisms in human bronchial epithelial cells.2013
- Author(s)
  Noguchi S, Hijikata M, Hamano E, Matsushita I, Ito H, Ohashi J, Nagase T, Keicho N.
- Journal Title
  
  Immunogenetics
  
  Volume: 65 Issue: 2 Pages: 107-114
- DOI
  10.1007/s00251-012-0663-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24501339
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer.2013
- Author(s)
  Kawakami M, Morita S, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nakajima J, Yatomi Y, Nagase T, Fukayama M, Takai D.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 6 Pages: 598-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045
[Journal Article] Detection of novel paraja ring finger 2-fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non-small cell lung cancer.2013
- Author(s)
  Kawakami M, Ishikawa R, Amano Y, Sunohara M, Watanabe K, Ohishi N, Yatomi Y, Nakajima J, Fukayama M, Nagase T, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 11 Pages: 1447-1454
- DOI
  10.1111/cas.12250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24659267, KAKENHI-PROJECT-25860402
[Journal Article] Effect of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1) on airway epithelial cells.2013
- Author(s)
  Narumoto O, Niikura Y, Ishii S, Morihara H, Okashiro S, Nakahari T, Nakano T, Matsumura H, Shimamoto C, Moriwaki Y, Misawa H, Yamashita N, Nagase T, Kawashima K, Yamashita N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 438 Issue: 1 Pages: 175-179
- DOI
  10.1016/j.bbrc.2013.07.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-25293020, KAKENHI-PROJECT-25460660
[Journal Article] Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells.2013
- Author(s)
  Noguchi S, Hamano E, Matsushita I, Hijikata M, Ito H, Nagase T, Keicho N.
- Journal Title
  
  Hum Immunol
  
  Volume: 74 Issue: 3 Pages: 395-401
- DOI
  10.1016/j.humimm.2012.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24501339
[Journal Article] Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells.2012
- Author(s)
  Mikami Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 428 Issue: 4 Pages: 451-7
- DOI
  10.1016/j.bbrc.2012.10.097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-24591125
[Journal Article] Characterization of human lung cancer-associated fibroblasts in three dimensional in vitro co-culture model2012
- Author(s)
  Masafumi Horie, Akira Saito, Mitsuhiro Ohshima, Yasuyuki Morishita, Jun Nakajima, Tadashi Kohyama, Takahide Nagase
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 423 Issue: 2 Pages: 158-163
- DOI
  10.1371/journal.pone.0056587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592637, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23790899, KAKENHI-PROJECT-24689018, KAKENHI-PUBLICLY-23112702
[Journal Article] Suppression of transforming growth factor β1 in lung alveolar epithelium-decells using adeno-associated virus type 2/5 vectors to carry short hairpin RNA2011
- Author(s)
  Kage H, Sugimoto K, Sano A, Kitagawa H, Nagase T, Ohishi N, Takai D
- Journal Title
  
  Exp Lung Res
  
  Volume: 37 Pages: 175-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045
[Journal Article] Simultaneous stimulation with TGF-β1-and TNF-α induces epithelial mesenchymal transition in bronchial epithelial cells2011
- Author(s)
  Kamitani S, Yamauchi Y, Kawasaki S, Takami K, Takizawa H, Nagase T, Kohyama T
- Journal Title
  
  Int Arch Allergy Immnunol
  
  Volume: 155 Pages: 119-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045
[Journal Article] Polymerase reaction without primers throughout for the reconstruction of full-length cDNA from products of rapid amplification of cDNA ends (RACE)2011
- Author(s)
  Sunohara M, Kawasaki M, Kage H, Watanabe K, Emoto N, Nagase T, Ohishi N, Takai D
- Journal Title
  
  Biotechnol Lett
  
  Volume: 33 Pages: 1301-1307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045
[Journal Article] Histamine stimulates human lung fibroblast migration.2010
- Author(s)
  Kohyama T, Yamauchi Y, Takizawa H, Kamitani S, Kawasaki S, Nagase T.
- Journal Title
  
  Mol Cell Biochem
  
  Volume: 337 Pages: 77-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1(slurp-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine ~and human asthmatic conditions.2010
- Author(s)
  Narumoto O, Horiguchi K, Horiguchi S, Moriwaki Y, Takano-Ohmuro H, Shoji S, Misawa H, Yamashita N, Nagase T, Kawashima K, Yamashita N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 398 Pages: 713-718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Tumor necrosis factor-alpha enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-beta1.2010
- Author(s)
  Yamauchi Y, Kohyama T, Takizawa H, Kamitani S, Desaki M, Takami K, Kawasaki S, Kato J, Nagase T
- Journal Title
  
  Exp Lung Res 36
  
  Pages: 12-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Identification of GOS2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches.2010
- Author(s)
  Kusakabe M, Kutomi T, Watanabe K, Emoto N, Aki N, Kage H, Hamano E, Kitagawa H, Nagase T, Sano A, Yoshida Y, Fukami T, Murakawa T, Nakajima J, Takamoto S, Ota S, Fukayama M, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Int J Cancer 15 : 126
  
  Pages: 1895-1902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor.2010
- Author(s)
  Hirota N, Yasuda D, Hashidate T, Yamamoto T, Yamaguchi S, Nagamune T, Nagase T, Shimizu T, Nakamura M
- Journal Title
  
  J Biol Chem 19 : 285
  
  Pages: 5931-5940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Tumor necrosis factor-alpha enhances 'both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-betal.2010
- Author(s)
  Yamauchi Y, Kohyama T, Takizawa H, Kamitani S, Desaki M, Takami K, Kawasaki S, Kato J, Nagase T.
- Journal Title
  
  Exp Lung Res
  
  Volume: 36 Pages: 12-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Histamine stimulates human lung fibroblast migration.2010
- Author(s)
  Kohyama T, Yamauchi Y, Takizawa H, Kamitani S, Kawasaki S, Nagase T
- Journal Title
  
  Mol Cell Biochem 337
  
  Pages: 77-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.2009
- Author(s)
  Saito RA, Watabe T, Horiguchi K, Kohyama T, Saitoh M, Nagase T, Miyazono K
- Journal Title
  
  Cancer Res 69
  
  Pages: 2783-2791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Procaterol inhibits lung fibroblast migration.2009
- Author(s)
  Kohyama T, Yamauchi Y, Takizawa H, Itakura S, Kamitani S, Desaki M, Kawasaki S, Nagase T
- Journal Title
  
  Inflammation 32
  
  Pages: 387-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.2009
- Author(s)
  Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H
- Journal Title
  
  Am J Respir Crit Care Med 180
  
  Pages: 326-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.2009
- Author(s)
  Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kutihara H.
- Journal Title
  
  Am J Respir Crit Care Med 180
  
  Pages: 326-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells2009
- Author(s)
  Saito RA, Watabe T, Horiguchi K, Kohyama T, Saitoh M, Nagase T, Miyazono K
- Journal Title
  
  Cancer Res 69
  
  Pages: 2783-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.2009
- Author(s)
  Saito RA, Watabe T, Horiguchi K, Kohyama T, Saitoh M, Nagase T, Miyazono K.
- Journal Title
  
  Cancer Res 69
  
  Pages: 2783-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Impact of DNA demethylation of the G0S2 gene on the transcrip tion of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.2009
- Author(s)
  Kusakabe M, Watanabe K, Emoto N, Aki N, Kage H, Nagase T, Nakajima J, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 1283-1287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice2009
- Author(s)
  Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H
- Journal Title
  
  Am J Respir Crit Care Med 180
  
  Pages: 326-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Sequential and quantitative analysis of a murine model of elastase-induced emp hysema.2008
- Author(s)
  Kawakami M, Matsuo Y, Yoshiura K, Nagase T, Yamashita N.
- Journal Title
  
  Biol Pharm Bull 31
  
  Pages: 1434-1438
- NAID
  110006792116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Renaltubular dysmorphogenesis leading to multicystic formation and lung emphysema in mice lacking TAZ.2008
- Author(s)
  Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J, Sato T, Asano T, Kurihara Y, Kurihara H
- Journal Title
  
  Am J Physiol 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Multiple renal cysts with concentration defects and pulmonary emphysema in mice lacking TAZ.2008
- Author(s)
  Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J, Sato T, Asano T, Kurihara Y, Kurihara H.
- Journal Title
  
  Am J Physiol 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Effect of dexamethasone on voltage-gated Na+ channel in cultured human bron chial smooth muscle cells.2008
- Author(s)
  Nakajima T, Jo T, Meguro K, Ounuma H, Ma J, Kubota N, Imuta H, Takano H, Iida H, Nagase T , Nagata T.
- Journal Title
  
  Life Sci 825
  
  Pages: 1210-1215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] 12-h pretreatment with methylprednisolone versus placebo for prevention of postextubation laryngeal oedema : a randomised double-blind trial (Correspondence letter)2007
- Author(s)
  Goto Y, Nagase T
- Journal Title
  
  Lancet 370
  
  Pages: 25-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Calcitonin gene-related peptide mediates acid-induced lung injury in mice.2007
- Author(s)
  Aoki-Nagase T, Nagase T, Oh-hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, Nagata T, Kurihara H, Ouchi Y
- Journal Title
  
  Respirology 12
  
  Pages: 807-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Calcitonin gene-related peptide mediates acid-induced lung injury in mice2007
- Author(s)
  Aoki-Nagase T, Nagase T, Oh-hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, Nagata T, Kurihara H, Ouchi Y
- Journal Title
  
  Respirology 12
  
  Pages: 807-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Beta-defensin overexpression induces progressive muscle degeneration in mice.2007
- Author(s)
  Yamaguchi Y, Nagase T, Tomita T, Nakamura K, Fukuhara S, Amano T, Yamamoto H, Ide Y, Suzuki M, Teramoto S, Asano T, Kangawa K, Nakagata N, Ouchi Y, Kurihara H.
- Journal Title
  
  Am J Physiol Cell Physiol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Beta-defensin overexpression induces progressive muscle degeneration in mice2007
- Author(s)
  Yamaguchi Y, Nagase T, Tomita T, Nakamura K, Fukuhara S, Amano T, Yamamoto H, Ide Y, Suzuki M, Teramoto S, Asano T, Kangawa K, Nakagata N, Ouchi Y, Kurihara H
- Journal Title
  
  Am J Physiol Cell Physiol 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Calcitonin gene-related peptide mediates acid-induced lung injury in mice.2007
- Author(s)
  Aoki-Nagase T, Nagase T, Oh-hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, nagata Y, Kurihara H, Ouchi Y.
- Journal Title
  
  Respirology (in press)
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] The Induction of H3K9 Methylation by PIWIL4 at the p16Ink4a Locus.2007
- Author(s)
  Sugimoto K, Kage H, Aki N, Sano A, Kitagawa H, Nagase T, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Biochem Biophys Res Commun 359
  
  Pages: 497-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Beta-defensin overexpression induces progressive muscle degeneration in mice.2007
- Author(s)
  Yamaguchi Y, Nagase T, Nakamura K, Fukuhara S, Amano T, Yamamoto H, Ide Y, Suzuki M, Teramoto S, Asano T, Kangawa K, Nakagata N, Ouchi Y, Kurihara H.
- Journal Title
  
  Am J. Physiol Cell Physiol (in press)
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Impaired innate adrenomedullin function deteriorates airway hyperresponsiveness in mice: possible roles of allergen-induced airway wall remodeling2007
- Author(s)
  Yamamoto H, Naease T, Shindo T, Teramoto S, Aoki-Nagase T, Yamaguchi Y, Yokomizo T, Nagai R, Kurihara H, Ouchi Y
- Journal Title
  
  J Appl Physiol 102
  
  Pages: 2361-2368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Calcitonin gene-related peptide mediates acid-induced lung injury in mice.2007
- Author(s)
  Aoki-Nagase T, Nagase T, Oh-hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, Nagata T, Kurihara H, Ouchi Y
- Journal Title
  
  Respirology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Calcitonin gene-related peptide mediates acid-induced lung injury in mice.2007
- Author(s)
  Aoki-Nagase T, Nagase T, Oh-hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, Nagata T, Kurihara H, Ouchi Y.
- Journal Title
  
  Respirology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Impaired innate adrenomedullin function deteriorates airway hyperresponsiveness in mice : possible roles of allergen-induced airway wall remodeling.2007
- Author(s)
  Yamamoto H, Nagase T, Shindo T, Teramoto S, Aoki-Nagase T, Yamaguchi Y, Yokomizo T, Nagai R, Kurihara H, Ouchi Y
- Journal Title
  
  J Appl Physiol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Calcitonin gene-related peptide mediates acid-induced lung injury in mice2007
- Author(s)
  Aoki-Nagase T, Naease T, Oh-hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, Nagata T, Kurihara H, Ouchi Y
- Journal Title
  
  Respirology 12
  
  Pages: 807-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Impaired innate adrenomedullin function deteriorates airway hyperresponsiveness in mice : possible roles of allergen-induced airway wall remodeling.2007
- Author(s)
  Yamamoto H, Nagase T, Shindo T, Teramoto S, Aoki-Nagase T, Yamaguchi Y, Yokomizo T, Nagai R, Kurihara H, Ouchi Y.
- Journal Title
  
  J Appl Physiol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] A second-generation profiling system for quantitative methylation analysis of multiple gene promoters : application to lung cancer.2007
- Author(s)
  Sano A, Kage H, Sugimoto K, Kitagawa H, Aki N, Goto A, Fukuyama M, Nakajima J, Takamoto S, Nagase T, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Oncogene 26
  
  Pages: 6518-6525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Beta-defensin overexpression induces progressive muscle degeneration in mice.2007
- Author(s)
  Yamaguchi Y, Nagase T, Tomita T, Nakamura K, Fukuhara S, Amano T, Yamamoto H, Ide Y, Suzuki M, Teramoto S, Asano T, Kangawa K, Nakagata N, Ouchi Y, Kurihara H
- Journal Title
  
  Am J Physiol Cell Physiol 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Impaired innate adrenomedullin function deteriorates airway hyperresponsiveness in mice: possible roles of allergen-induced airway wall remodeling.2007
- Author(s)
  Yamamoto H, Nagase T, Shindo T, Teramoto S, Aoki-Nagase T, Yamaguchi Y, Yokomizo T, Nagai R, Kurihara H, Ouchi Y
- Journal Title
  
  J Appl Physiol 102
  
  Pages: 2361-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Beta-defensin overexpression induces progressive muscle degeneration in mice.2007
- Author(s)
  Yamaguchi Y, Nagase T, Tomita T, Nakamura K, Fukuhara S, Amano T, Yamamoto H, Ide Y, Suzuki M, Teramoto S, Asano T, Kangawa K, Nakagata N, Ouchi Y, Kurihara H
- Journal Title
  
  Am J Physiol Cell Physiol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Adrenomedullin insufficiency increases allergen induced airway hyperresponsiveness in mice2007
- Author(s)
  Yamamoto H, Nagase T, Shindo T, Aoki-Nagase T, Nakamura K, Yamaguchi Y, Hanaoka Y, Kurihara H, Ouchi Y
- Journal Title
  
  J Appl Physiol 102
  
  Pages: 2361-2368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] Molecular mechanisms underlying inflammatory lung diseases in the elderly : development of a novel therapeutic strategy for acute lung injury and pulmonary fibrosis.2005
- Author(s)
  Nagase T, Aoki-Nagase T, Yamaguchi Y, Yamamoto H, Ouchi Y
- Journal Title
  
  Griatrics Gerontology International 5
  
  Pages: 139-145
- NAID
  10017127922
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Molecular mechanisms underlying inflammatory lung diseases in the elderly : development of a novel therapeutic strategy for acute lung injury and pulmonary fibrosis.2005
- Author(s)
  Nagase T, Aoki-Nagase T, Yamaguchi Y, Yamamoto H, Ouchi Y.
- Journal Title
  
  Griatrics Gerontology International 5
  
  Pages: 139-145
- NAID
  10017127922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses.2005
- Author(s)
  Terawaki K, Yokomizo T, Nagase T, Toda A, Taniguchi M, Hashizume K, Yagi T, Shimizu T
- Journal Title
  
  J Immunol 175
  
  Pages: 4217-4225
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Betaine improved restriction digestion.2005
- Author(s)
  Sugimoto K, Makihara T, Saito A, Ohishi N, Nagase T, Takai D.
- Journal Title
  
  Biochem Biophys Res Commun 337
  
  Pages: 1027-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Molecular mechanisms underlying inflammatory lung diseases in the elderly : Development of a novel therapeutic strategy for acute lung injury and pulmonary fibrosis.2005
- Author(s)
  Nagase T, Aoki-Nagase T, Yamaguchi Y, Yamamoto H, Ouchi Y.
- Journal Title
  
  Geriatrics and Gerontology International 5
  
  Pages: 139-145
- NAID
  10017127922
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Leukotriene D_4 potentiates fibronectin-induced migration of human lung fibroblasts.2005
- Author(s)
  Kato J, Kohyama T, Okazaki H, Desaki M, Rennard SI, Takizawa H, Nagase T
- Journal Title
  
  Clinical Immunol 117
  
  Pages: 177-181
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Leukotriene D4 potentiates fibronectin-induced migration of human lung fibroblasts.2005
- Author(s)
  Kato J, Kohyama T, Okazaki H, Desaki M, Nagase T, Rennard SI, Takizawa H.
- Journal Title
  
  Clin Immunol 117(2)
  
  Pages: 177-181
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Acute and chronic effects of eicosapentaenoic acid on voltage-gated sodium channel expressed in cultured human bronchial smooth muscle cells.2005
- Author(s)
  Jo T, Iida H, Kishida S, Imuta H, Oonuma H, Nagata T, Hara H, Iwasawa K, Soma M, Sato Y, Nagase T, Nagai R, Nakajima T.
- Journal Title
  
  Biochem Biophys Res Commun 331
  
  Pages: 1452-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Betaine improved restriction digestion.2005
- Author(s)
  Sugimoto K, Makihara T, Saito A, Ohishi N, Nagase T, Takai D
- Journal Title
  
  Biochem Biophys Res Commun 337
  
  Pages: 1027-1029
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Acute and chronic effects of eicosapentaenoic acid on voltage-gated sodium channel expressed in cultured human bronchial smooth muscle cells.2005
- Author(s)
  Jo T, Iida H, Kishida S, Imuta H, Oonuma H, Nagata T, Hara H, Iwasawa K, Soma M, Sato Y, Nagase T, Nagai R, Nakajima T
- Journal Title
  
  Biochem Biophys Res Commun 331
  
  Pages: 1452-1459
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses.2005
- Author(s)
  Terawaki K, Yokomizo T, Nagase T, Toda A, Taniguchi M, Hashizume K, Yagi T, Shimizu T.
- Journal Title
  
  J Immunol 175
  
  Pages: 4217-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Leukotriene D_4 potentiates fibronectin-induced migration of human lung fibroblasts.2005
- Author(s)
  Kato J, Kohyama T, Okazaki H, Desaki M, Rennard SI, Takizawa H, Nagase T.
- Journal Title
  
  Clinical Immunol 117
  
  Pages: 177-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] New therapeutic key for cystic fibrosis : a role for lipoxins.2004
- Author(s)
  Takai D, Nagase T, Shimizu T.
- Journal Title
  
  Nature Immunol 5
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-15659195
[Journal Article] New therapeutic key for cystic fibrosis : a role for lipoxins. News and Views(論文解説)2004
- Author(s)
  Takai D, Nagase T, Shimizu T
- Journal Title
  
  Nature Immunol 5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] New therapeutic key for cystic fibrosis : a role for lipoxins.2004
- Author(s)
  Takai D, Nagase T, Shimizu T.
- Journal Title
  
  Nature Immunol 5(News and Views)
  
  Pages: 357-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model.2004
- Author(s)
  Ishii S, NagaseT, Shindou H, Takizawa H, Ouchi Y, Shimizu T
- Journal Title
  
  J Immunol 172
  
  Pages: 7095-7102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model.2004
- Author(s)
  Ishii S, Nagase T, Shindou H, Takizawa H, Ouchi Y, Shimizu T.
- Journal Title
  
  J Immunol 172
  
  Pages: 7095-7102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Voltage-gated sodium channel expressed in cultured human smooth muscle cells : Involvement of SCN9A.2004
- Author(s)
  Jo T, Nagata T, Iida H, Imuta H, Iwasawa K, Ma J, Hara K, Omata M, Nagai R, Takizawa H, Nagase T, Nakajima T
- Journal Title
  
  FEBS Lett 567
  
  Pages: 339-343
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model.2004
- Author(s)
  Ishii S, Nagase T, Shindou H, Takizawa H, Ouchi Y, Shimizu T.
- Journal Title
  
  J Immunol 172
  
  Pages: 7095-7102
- Data Source
  KAKENHI-PROJECT-15659195
[Journal Article] Voltage-gated sodium channel expressed in cultured human smooth muscle cells : Involvement of SCN9A.2004
- Author(s)
  Jo T, Nagata T, Iida H, Imuta H, Iwasawa K, Ma J, Hara K, Omata M, Nagai R, Takizawa H, Nagase T, Nakajima T.
- Journal Title
  
  FEBS Lett 567
  
  Pages: 339-343
- Data Source
  KAKENHI-PROJECT-15659195
[Journal Article] Voltage-gated sodium channel expressed in cultured human smooth muscle cells : Involvement of SCN9A.2004
- Author(s)
  Jo T, Nagata T, Iida H, Imuta H, Iwasawa K, Ma J, Hara K, Omata M, Nagai R, Takizawa H, Nagase T, Nakajima T.
- Journal Title
  
  FEBS Lett 567
  
  Pages: 339-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] New therapeutic key for cystic fibrosis : a role for lipoxins.2004
- Author(s)
  Takai D, Nagase T, Shimizu T
- Journal Title
  
  Nature Immunol 5
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model.2004
- Author(s)
  Ishii S, Nagase T, Shindou H, Takizawa H, Ouchi Y, Shimzu T
- Journal Title
  
  J Immunol 172
  
  Pages: 7095-7102
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] The effects of obstructive sleep apnea on circulating ICAM-1, IL-8 and MCP-1.2003
- Author(s)
  Ohga E, Tomita T, Wada H, Yamamoto H, Nagase T, Ouchi Y
- Journal Title
  
  J Appl Physiol 94
  
  Pages: 179-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] The effects of obstructive sleep apnea on circulating ICAM-1, IL-8 and MCP-1.2003
- Author(s)
  Ohga E, Tomita T, Wada H, Yamamoto H, Nagase T, Ouchi Y.
- Journal Title
  
  J Appl Physiol 94
  
  Pages: 179-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] A potent inhibitor of cytosolic phospholipase A_2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice.2003
- Author(s)
  Nagase T, Uozumi N, Aoki-Nagase T, Terawaki K, Ishii S, Tomita T, Yamamoto H, Hashizume K, Ouchi Y, Shimizu T.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Journal Article] A potent inhibitor of cytosolic phospholipase A_2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice.2003
- Author(s)
  Nagase T, Uozumi N, Aoki-Nagase T, Terawaki K, Ishii S, Tomita T, Yamamoto H, Hashizume K, Ouchi Y, Shimizu T
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209029
[Patent] 筋ジストロフィー症の病態モデル哺乳動物、及びその製造方法
- Inventor(s)
  栗原裕基, 大内尉義, 長瀬隆英, 山口泰弘
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] レプチンによる肺線維芽細胞のサイトカイン産生増強作用とその機序の検討2020
- Author(s)
  渡邊かおる、鈴川真穂、長瀬隆英 et. al.
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-16H02653
[Presentation] Effects of ASCL1 expression on cytokine/chemokine expression and tumorigenesis.2019
- Author(s)
  Miyashita N, Horie M, Mikami Y, Urushiyama H, Fukuda K, Makita K, Matsuzaki H, Saito A, Nagase T.
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-16H02653
[Presentation] Respiratory research using cellular, molecular and physiologic approaches2017
- Author(s)
  Nagase T
- Organizer
  Asian Pacific Society of Respirology (APSR),2017, Sydney
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653
[Presentation] Recent progress in respiratory cells and molecular biology2016
- Author(s)
  長瀬隆英
- Organizer
  APSR 2016
- Place of Presentation
  バンコク
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653
[Presentation] Hot topics in experimental animal model2014
- Author(s)
  Nagase T
- Organizer
  APSR 2014
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-23249045
[Presentation] Interleukin-17A Enhances Interferon-Gamma-Induced CXCL10/IP-10 Production In BEAS-2B Human Bronchial Epithelial Cells.2013
- Author(s)
  Yasuhiro Yamauchi, Taisuke Jo, Masafumi Horie, Yu Mikami, Satoshi Noguchi, Osamu Narumoto, Kazutaka Takami, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase,
- Organizer
  American Thoracic Society　International Conference 2013
- Place of Presentation
  Pennsylvania convention center (アメリカ、フィラデルフィア）
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway.2013
- Author(s)
  Yu Mikami, Yasuhiro Yamauchi, Masafumi Horie, Satoshi Noguchi, Osamu Narumoto, Taisuke Jo, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
- Organizer
  American Thoracic Society　International Conference 2013
- Place of Presentation
  Pennsylvania convention center (アメリカ、フィラデルフィア）
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway2013
- Author(s)
  Yu Mikami, Yasuhiro Yamauchi, Masafumi Horie, Satoshi Noguchi, Osamu Narumoto, Taisuke Jo, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Pennsylvania Convention Center
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] モデルマウスを用いた呼吸器疾患の病態解明2013
- Author(s)
  長瀬隆英
- Organizer
  第53回日本呼吸器学会総会
- Place of Presentation
  東京（東京国際フォーラム）
- Invited
- Data Source
  KAKENHI-PROJECT-23249045
[Presentation] Interleukin-17A Enhances Interferon- Gamma-Induced CXCL10/IP-10 Production In BEAS-2B Human Bronchial Epithelial Cells2013
- Author(s)
  Yasuhiro Yamauchi, Taisuke Jo, Masafumi Horie, Yu Mikami, Satoshi Noguchi, Osamu Narumoto, Kazutaka Takami, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Pennsylvania Convention Center
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Cellular and molecular models of lung diseases.2012
- Author(s)
  Nagase T
- Organizer
  APSR Meeting
- Place of Presentation
  Hong Kong
- Invited
- Data Source
  KAKENHI-PROJECT-23249045
[Presentation] Molecular mechanisms underlying respiratory diseases2011
- Author(s)
  長瀬隆英
- Organizer
  16th APSR Meeting
- Place of Presentation
  上海(中国)(招待講演)
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-23249045
[Presentation] Respiratory research using genetically-engineered mice.2009
- Author(s)
  長瀬隆英
- Organizer
  The 14th APSR Meeting Seoul.
- Place of Presentation
  ソウル、大韓民国(招待講演)
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] Respiratory research using genetically-engineered mice2009
- Author(s)
  長瀬隆英
- Organizer
  The 14th APSR Meeting
- Place of Presentation
  Seoul,韓国
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] Respiratory research using genetically-engineered mice2009
- Author(s)
  長瀬隆英
- Organizer
  The14th APSR Meeting
- Place of Presentation
  Seoul
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] 慢性閉塞性肺疾患2008
- Author(s)
  長瀬隆英、教育企画
- Organizer
  第50回日本老年医学会総会
- Place of Presentation
  幕張
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] 肺炎症における脂質性メディエーターに関して2007
- Author(s)
  長瀬隆英
- Organizer
  第47回日本呼吸器学会総会 (特別講演)
- Place of Presentation
  東京
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] 高齢者COPDの臨床2007
- Author(s)
  長瀬隆英
- Organizer
  第49回日本老年医学会総会
- Place of Presentation
  札幌
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] 肺炎症における脂質性メディエーターに関して2007
- Author(s)
  長瀬隆英
- Organizer
  第47回日本呼吸器学会総会
- Place of Presentation
  東京(特別講演)
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-19209031
[Presentation] 肺炎症における脂質性メディエーターに関して2007
- Author(s)
  長瀬隆英
- Organizer
  第47回日本呼吸器学会総会(特別講演)
- Place of Presentation
  東京
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-19209031

1. YAMAMOTO Hiroshi (10361487)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. KUHIHARA Hiroki (20221947)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
3. ISHI Satoshi (10300815)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. SHIMIZU Takao (80127092)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. SHINDO Takayuki (90345215)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. YAMAGUCHI Yasuhiro (60376473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. UOZUMI Naonori (70313096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YOKOMIZO Takehiko (60302840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 大賀栄次郎 (00323577)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TAKAI Daiya (90361493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. KUROSAWA Hajime (60333788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OGAWA Hiromasa (90361162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOHZUKI Masahiro (70234698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IROKAWA Toshiya (70375179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. JO Taisuke (30376470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. YAMAUCHI Yasuhiro (00323585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
17. SAITO Akira (90591412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. KOHYAMA Tadashi (00302703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. TOMIYA Tetsuji (50345203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TERAMOTO Shinji (50282629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KAWAGUCHI Hiroshi (40282660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 石井正紀 (20724438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. OHGA Fujiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TARUI Megumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. YAMAGUCHI Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. HORIE Masafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. TERASAKI Mika

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 渡邊広祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
29. 大島光宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. MICKE Patrick

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 平石尚久

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 寺崎泰弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. 漆山博和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 河津正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 砂金秀章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGASE Takahide 長瀬 隆英

長瀬 隆英 ナガセ タカヒデ

Research Projects

Research Products

Co-Researchers

Establishment and application of the physiological biomarkers in older people at the end-of-life

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

The investigation of respiratory diseases and development of novel therapeutics using up-to-date molecular and cellular techniquesPrincipal Investigator

Principal Investigator

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Research Institution

The investigation of genes related to refractory respiratory diseases and development of novel therapeuticsPrincipal Investigator

Principal Investigator

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Research Institution

The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis

Principal Investigator

Project Period (FY)

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Research Institution

Pysical Inactivities and systemic inflammation. Investigation of anti-inflammatory effects of exercise in patiens with chronic respiratory disease

Principal Investigator

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Research Institution

Investigation about the effect of Adrenomedullin on pulmonary function and development of emphysema of old mice

Principal Investigator

Project Period (FY)

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Research Institution

The investigation of molecular mechanisms underlying refractory respiratory diseases and exploration of novel therapeutic targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Pathophysiological role of Adrenomedullin on the etiology of bronchial asthma and pulmonary fibrosis

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

未知の抗菌ペプチドの探索および炎症性肺疾患発症制御の可能性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of therapeutic targets for refractory inflammatory lung diseases and development of novel therapeutic strategiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental approach for gene therapy of pulmonary emphysema focusing on Klotho gene and GSTP1 gene

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of CGRP family peptides in the molecular mechanisms underlying bronchial asthma: the development of novel therapeutic approach

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

炎症性肺疾患発症分子機構における抗菌ペプチドdefensinの意義Principal Investigator

Principal Investigator

Project Period (FY)

NAGASE Takahide 長瀬隆英

長瀬隆英ナガセタカヒデ