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Nishida Shozo  西田 升三

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NISHIDA Shozo  西田 升三

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Researcher Number 40208187
Affiliation (Current) 2025: 近畿大学, 薬学部, 研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 近畿大学, 薬学部, 教授
2012 – 2017: 近畿大学, 薬学部, 教授
2004: Kinki University, School of Pharmaceutical Sciences, 薬学部, 教授
2002 – 2004: 近畿大学, 薬学部, 助教授
1999: KINKI UNIVERSITY, SCHOOL OF PHARM.., 薬学部, 講師
1993 – 1998: 近畿大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Except Principal Investigator
General internal medicine(including psychosomatic medicine) / Cerebral neurosurgery
Keywords
Principal Investigator
Mn-SOD / 慢性骨髄性白血病 / apoptosis / SOD / 頭頸部腫瘍 / 治療抵抗性 / BCR-ABL1阻害薬 / PKC / TNFα / Head & Neck … More / Cancer / Cu,Zn-SOD / アポトーシス / スーパーオキサイドジスムターゼ / 耐性 / ダサチニブ / イマチニブ耐性 / BCR-ABL阻害薬 / イマチニブ / drug resistance / signal transdction / 薬剤耐性 / シグナル伝達 / Mu-SOD / Cu, Zu-SOD / radical / Cu, Zn-SOD / CuZn-SOD / Apoptosis / CAM-DR / 多発性骨髄腫 / 分子標的薬 / 抗癌剤耐性 / TNF-α / Mn‐SOD / melaroma / プロテインキナーゼC … More
Except Principal Investigator
SHR / DDC / 貪食能 / 肺胞マクロファージ / マクロファージ / 自然免疫 / 転移 / がん / 慢性ストレス / APOPTOSIS / NEURONAL DEATH / SPINAL CORD / ISCHEMIA / NF-kB / NAC / 脊髄虚血 / アポトーシス Less
  • Research Projects

    (11 results)
  • Research Products

    (78 results)
  • Co-Researchers

    (8 People)
  •  分子標的薬耐性慢性骨髄性白血病における耐性獲得機序の解明と新規標的治療の開発Principal Investigator

    • Principal Investigator
      西田 升三
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Kindai University
  •  Identification of resistance factors and development of novel strategy to overcome resistance in treatment-resistant chronic myeloid leukemiaPrincipal Investigator

    • Principal Investigator
      NISHIDA Shozo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Kindai University
  •  Identification of imatinib resistance factor and the therapeutic strategies to overcome resistance in chronic myeloid leukemiaPrincipal Investigator

    • Principal Investigator
      NISHIDA Shozo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kindai University
  •  Chronic stress state promotes cancer metastatic ability

    • Principal Investigator
      ICHIDA Seiji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Kinki University
  •  Investigation for the mechanism of anti-cancer drugs resistance and therapeutic strategy in multiple myelomaPrincipal Investigator

    • Principal Investigator
      NISHIDA Shozo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kinki University
  •  Pretreatment with PKC Inhibitor enhances TNF-alpha induced apoptosis in TNF-aloha resistant cells and Enhancement of TNF induced antitumor activity by Inhibition of superoxide dismutase inductionPrincipal Investigator

    • Principal Investigator
      NISHIDA Shozo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kinki University
  •  SPINAL ISCHEMIA, ITS MECHANISM AND STRATEGY OF TREATMENT-A NEW MODEL AND GLIAL REACTION AND INDUCTION

    • Principal Investigator
      AKAI Fumiharu
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KINKI UNIVERSITY
  •  Mechanism of induction of apoptosis by radicals and enhancement of antitumor activity of anticancer drugs and irradiation in head and neck cancerPrincipal Investigator

    • Principal Investigator
      NISHIDA Shozo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kinki University School of Medicine
  •  Enhancement of antitumor activity of anticancer drugs and irradiation in head and neck cancerPrincipal Investigator

    • Principal Investigator
      NISHIDA Shozo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kinki University School of Medicine
  •  頭頸部癌での抗癌剤・放射線による腫瘍殺傷効果の増強《スーパーオキサイドジスムターゼ(SOD)の誘導阻害効果》Principal Investigator

    • Principal Investigator
      西田 升三
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kinki University
  •  頭頸部癌での抗癌剤・放射線治療における腫瘍殺傷効果の増強《スーパーオキサイドジスムターゼ(SOD)の生化学的誘導機序の解明とその阻害効果》Principal Investigator

    • Principal Investigator
      西田 升三
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kinki University

All 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Bim downregulation by activation of NF-κB p65, Akt, and ERK1/2 is associated with adriamycin and dexamethasone resistance in multiple myeloma cells2023

    • Author(s)
      Tsubaki M, Takeda T, Matsuda T, Kishimoto K, Tanaka R, Tsurushima K, Ishizaka T, Nishida S.
    • Journal Title

      Clin Exp Med.

      Volume: - Issue: 5 Pages: 1-11

    • DOI

      10.1007/s10238-022-00951-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Activation of ERK1/2 by MOS and TPL2 leads to dasatinib resistance in chronic myeloid leukaemia cells2023

    • Author(s)
      Tsubaki M, Takeda T, Koumoto Y, Usami T, Matsuda T, Seki S, Sakai K, Nishio K, Nishida S.
    • Journal Title

      Cell Prolif.

      Volume: - Issue: 6 Pages: 1-9

    • DOI

      10.1111/cpr.13420

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168, KAKENHI-PROJECT-23K06270
  • [Journal Article] Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy2023

    • Author(s)
      Tsubaki M, Takeda T, Matsuda T, Kishimoto K, Takefuji H, Taniwaki Y, Ueda M, Hoshida T, Tanabe K, Nishida S.
    • Journal Title

      Cancer Cell Int.

      Volume: 23 Issue: 1 Pages: 1-13

    • DOI

      10.1186/s12935-023-02884-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Hypoxia-inducible factor 1α inhibitor induces cell death via suppression of BCR-ABL1 and Met expression in BCR-ABL1 tyrosine kinase inhibitor sensitive and resistant chronic myeloid leukemia cells2023

    • Author(s)
      Tsubaki M, Takeda T, Matsuda T, Kimura A, Tanaka R, Nagayoshi S, Hoshida T, Tanabe K, Nishida S.
    • Journal Title

      BMB Rep.

      Volume: 56 Issue: 2 Pages: 78-83

    • DOI

      10.5483/bmbrep.2022-0095

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Combination treatment with statins and bezafibrate induces myotoxicity via inhibition of geranylgeranyl pyrophosphate biosynthesis and Rho activation in L6 myoblasts and myotube cells2022

    • Author(s)
      Tsubaki M, Takeda T, Mastuda T, Kimura A, Yanae M, Maeda A, Hoshida T, Tanabe K, Nishida S.
    • Journal Title

      J Physiol Pharmacol.

      Volume: 73 Pages: 137-152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Journal Article] Dimethyl Fumarate Induces Apoptosis via Inhibition of NF-κB and Enhances the Effect of Paclitaxel and Adriamycin in Human TNBC Cells2022

    • Author(s)
      Tsurushima K, Tsubaki M, Takeda T, Matsuda T, Kimura A, Takefuji H, Okada A, Sakamoto C, Ishizaka T, Nishida S.
    • Journal Title

      Int J Mol Sci.

      Volume: 23 Issue: 15 Pages: 1-13

    • DOI

      10.3390/ijms23158681

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in colon cancer cells harboring the PIK3CA mutation2021

    • Author(s)
      Morii Y, Tsubaki M, Takeda T, Otubo R, Seki S, Yamatomo Y, Imano M, Satou T, Shimomura K, Nishida S.
    • Journal Title

      Eur J Pharmacol.

      Volume: 898 Pages: 173957-173957

    • DOI

      10.1016/j.ejphar.2021.173957

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] FTI-277 and GGTI-289 induce apoptosis via inhibition of the Ras/ERK and Ras/mTOR pathway in head and neck carcinoma HEp-2 and HSC-3 cells.2021

    • Author(s)
      Tateishi K, Tsubaki M, Takeda T, Yamatomo Y, Imano M, Satou T, Nishida S.
    • Journal Title

      J BUON

      Volume: 26 Pages: 606-612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Journal Article] Interleukin 19 suppresses RANKL-induced osteoclastogenesis via the inhibition of NF-κB and p38MAPK activation and c-Fos expression in RAW264.7 cells.2021

    • Author(s)
      Tsubaki M, Takeda T, Matsuda T, Yamamoto Y, Higashinaka A, Yamamoto K, Tsurushima K, Ishizaka T, Nishida S.
    • Journal Title

      Cytokine

      Volume: 144 Pages: 155591-155591

    • DOI

      10.1016/j.cyto.2021.155591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Activation of Serum/Glucocorticoid Regulated Kinase 1/Nuclear Factor-κB Pathway Are Correlated with Low Sensitivity to Bortezomib and Ixazomib in Resistant Multiple Myeloma Cells2021

    • Author(s)
      Tsubaki M, Takeda T, Matsuda T, Seki S, Tomonari Y, Koizumi S, Nagatakiya M, Katsuyama M, Yamamoto Y, Tsurushima K, Ishizaka T, Nishida S.
    • Journal Title

      Biomedicines

      Volume: 9 Issue: 1 Pages: 33-33

    • DOI

      10.3390/biomedicines9010033

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Gabapentin and Duloxetine Prevent Oxaliplatin- and Paclitaxel-Induced Peripheral Neuropathy by Inhibiting Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Phosphorylation in Spinal Cords of Mice2021

    • Author(s)
      Kato N, Tateishi K, Tsubaki M, Takeda T, Matsumoto M, Tsurushima K, Ishizaka T, Nishida S.
    • Journal Title

      Pharmaceuticals (Basel).

      Volume: 14 Issue: 1 Pages: 30-30

    • DOI

      10.3390/ph14010030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] Rhosin Suppressed Tumor Cell Metastasis through Inhibition of Rho/YAP Pathway and Expression of RHAMM and CXCR4 in Melanoma and Breast Cancer Cells2021

    • Author(s)
      Tsubaki M, Genno S, Takeda T, Matsuda T, Kimura N, Yamashita Y, Morii Y, Shimomura K, Nishida S.
    • Journal Title

      Biomedicines

      Volume: 9 Issue: 1 Pages: 35-35

    • DOI

      10.3390/biomedicines9010035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells2020

    • Author(s)
      Tsubaki M, Seki S, Takeda T, Chihara A, Arai Y, Morii Y, Imano M, Satou T, Shimomura K, Nishida S.
    • Journal Title

      Int J Mol Sci.

      Volume: 21 Issue: 21 Pages: 7905-7905

    • DOI

      10.3390/ijms21217905

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07145, KAKENHI-PROJECT-20K07168
  • [Journal Article] The MIP-1α autocrine loop contributes to decreased sensitivity to anticancer drugs.2018

    • Author(s)
      Tsubaki M, Takeda T, Tomonari Y, Mashimo K, Koumoto YI, Hoshida S, Itoh T, Imano M, Satou T, Sakaguchi K, Nishida S.
    • Journal Title

      J Cell Physiol.

      Volume: 233 Issue: 5 Pages: 4258-4271

    • DOI

      10.1002/jcp.26245

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-16K18965
  • [Journal Article] Pioglitazone inhibits cancer cell growth through STAT3 inhibition and enhanced AIF expression via a PPARγ-independent pathway.2018

    • Author(s)
      Tsubaki M, Takeda T, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S.
    • Journal Title

      J Cell Physiol.

      Volume: 233 Issue: 4 Pages: 3638-3647

    • DOI

      10.1002/jcp.26225

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-17K01486, KAKENHI-PROJECT-16K18965
  • [Journal Article] Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.2018

    • Author(s)
      Tsubaki M, Takeda T, Asano RT, Matsuda T, Fujimoto SI, Itoh T, Imano M, Satou T, Nishida S.
    • Journal Title

      Toxicol In Vitro.

      Volume: 46 Pages: 284-293

    • DOI

      10.1016/j.tiv.2017.10.019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18965, KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-17K01486
  • [Journal Article] Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3.2018

    • Author(s)
      Takeda T, Tsubaki M, Tomonari Y, Kawashima K, Itoh T, Imano M, Satou T, Nishida S.
    • Journal Title

      Biomed Pharmacother.

      Volume: 100 Pages: 486-494

    • DOI

      10.1016/j.biopha.2018.02.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15530, KAKENHI-PROJECT-15K08116
  • [Journal Article] Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells.2017

    • Author(s)
      Tsubaki M, Takeda T, Kino T, Sakai K, Itoh T, Imano M, Nakayama T, Nishio K, Satou T, Nishida S.
    • Journal Title

      Oncotarget

      Volume: In press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Journal Article] Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells.2017

    • Author(s)
      Tsubaki M, Takeda T, Kino T, Sakai K, Itoh T, Imano M, Nakayama T, Nishio K, Satou T, Nishida S.
    • Journal Title

      Oncotarget.

      Volume: 8 Issue: 24 Pages: 38717-38730

    • DOI

      10.18632/oncotarget.16314

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18965, KAKENHI-PROJECT-15K00898, KAKENHI-PROJECT-15K08116
  • [Journal Article] Statins induce apoptosis through inhibition of Ras signaling pathways and enhancement of Bim and p27 expression in human hematopoietic tumor cells.2017

    • Author(s)
      Fujiwara D, Tsubaki M, Takeda T, Tomonari Y, Koumoto YI, Sakaguchi K, Nishida S.
    • Journal Title

      Tumour Biol.

      Volume: 39 Pages: 0-11

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Journal Article] The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.2017

    • Author(s)
      Tsubaki M, Fujiwara D, Takeda T, Kino T, Tomonari Y, Itoh T, Imano M, Satou T, Sakaguchi K, Nishida S.
    • Journal Title

      Clin Exp Pharmacol Physiol.

      Volume: 44 Issue: 2 Pages: 222-234

    • DOI

      10.1111/1440-1681.12690

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-15K00898
  • [Journal Article] Mangiferin induces apoptosis in multiple myeloma cell lines by suppressing the activation of nuclear factor kappa B-inducing kinase.2016

    • Author(s)
      Takeda T, Tsubaki M, Kino T, Yamagishi M, Iida M, Itoh T, Imano M, Tanabe G, Muraoka O, Satou T, Nishida S.
    • Journal Title

      Chem Biol Interact.

      Volume: 251 Pages: 26-33

    • DOI

      10.1016/j.cbi.2016.03.018

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-16K08313
  • [Journal Article] Statins inhibited the MIP-1α expression via inhibition of Ras/ERK and Ras/Akt pathways in myeloma cells.2016

    • Author(s)
      Tsubaki M, Mashimo K, Takeda T, Kino T, Fujita A, Itoh T, Imano M, Sakaguchi K, Satou T, Nishida S.
    • Journal Title

      Biomed Pharmacother.

      Volume: 78 Pages: 23-29

    • DOI

      10.1016/j.biopha.2015.12.017

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-26350597, KAKENHI-PROJECT-15K00898
  • [Journal Article] Mangiferin enhances the sensitivity of human multiple myeloma cells to anticancer drugs through suppression of the nuclear factor κB pathway2016

    • Author(s)
      Takeda T, Tsubaki M, Kino T, Kawamura A, Isoyama S, Itoh T, Imano M, Tanabe G, Muraoka O, Satou T, Nishida S
    • Journal Title

      Int J Oncol

      Volume: 48 Issue: 6 Pages: 303-309

    • DOI

      10.3892/ijo.2016.3470

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350597, KAKENHI-PROJECT-15K00898, KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-16K08313
  • [Journal Article] RANK-RANKL interactions are involved in cell adhesion-mediated drug resistance in multiple myeloma cell lines.2016

    • Author(s)
      Tsubaki M, Takeda T, Yoshizumi M, Ueda E, Itoh T, Imano M, Satou T, Nishida S.
    • Journal Title

      Tumour Biol.

      Volume: 37 Issue: 7 Pages: 9099-9110

    • DOI

      10.1007/s13277-015-4761-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Journal Article] Mangiferin, a novel nuclear factor kappa B-inducing kinase inhibitor, suppresses metastasis and tumor growth in a mouse metastatic melanoma model.2016

    • Author(s)
      Takeda T, Tsubaki M, Sakamoto K, Ichimura E, Enomoto A, Suzuki Y, Itoh T, Imano M, Tanabe G, Muraoka O, Matsuda H, Satou T, Nishida S.
    • Journal Title

      Toxicol Appl Pharmacol.

      Volume: 306 Pages: 105-112

    • DOI

      10.1016/j.taap.2016.07.005

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08116, KAKENHI-PROJECT-16K08313
  • [Journal Article] Overexpression of survivin via activation of ERK1/2, Akt, and NF-κB plays a central role in vincristine resistance in multiple myeloma cells.2015

    • Author(s)
      Tsubaki M, Takeda T, Ogawa N, Sakamoto K, Shimaoka H, Fujita A, Itoh T, Imano M, Ishizaka T, Satou T, Nishida S.
    • Journal Title

      Leuk Res.

      Volume: 39 Issue: 4 Pages: 445-52

    • DOI

      10.1016/j.leukres.2015.01.016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590224, KAKENHI-PROJECT-15K08116
  • [Journal Article] Bisphosphonates and statins inhibit expression and secretion of MIP-1α via suppression of Ras/MEK/ERK/AML-1A and Ras/PI3K/Akt/AML-1A pathways.2015

    • Author(s)
      Tsubaki M, Takeda T, Sakamoto K, Shimaoka H, Fujita A, Itoh T, Imano M, Mashimo K, Fujiwara D, Sakaguchi K, Satou T, Nishida S.
    • Journal Title

      Am J Cancer Res.

      Volume: 5 Pages: 168-79

    • Data Source
      KAKENHI-PROJECT-24590224
  • [Journal Article] PKC/MEK inhibitors suppress oxaliplatin-induced neuropathy and potentiate the antitumor effects.2015

    • Author(s)
      Tsubaki M, Takeda T, Tani T, Shimaoka H, Suzuyama N, Sakamoto K, Fujita A, Ogawa N, Itoh T, Imano M, Funakami Y, Ichida S, Satou T, Nishida S.
    • Journal Title

      Int J Cancer.

      Volume: In press Issue: 1 Pages: 243-250

    • DOI

      10.1002/ijc.29367

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590224, KAKENHI-PROJECT-25860071
  • [Journal Article] Statins improve survival by inhibiting spontaneous metastasis and tumor growth in a mouse melanoma model.2015

    • Author(s)
      Tsubaki M, Takeda T, Kino T, Obata N, Itoh T, Imano M, Mashimo K, Fujiwara D, Sakaguchi K, Satou T, Nishida S.
    • Journal Title

      Am J Cancer Res.

      Volume: 5 Pages: 3186-3197

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Journal Article] By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.2014

    • Author(s)
      Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, Takeda T, Ogawa N, Mashimo K, Fujiwara D, Mukai J, Sakaguchi K, Satou T, Nishida S
    • Journal Title

      Leuk Res

      Volume: 38 Issue: 1 Pages: 120-130

    • DOI

      10.1016/j.leukres.2013.10.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501009, KAKENHI-PROJECT-24590224
  • [Journal Article] Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.2014

    • Author(s)
      Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, Takeda T, Ogawa N, Mashimo K, Fujiwara D, Mukai J, Sakaguchi K, Satou T, Nishida S.
    • Journal Title

      J Biomed Sci.

      Volume: 21 Issue: 1 Pages: 10-10

    • DOI

      10.1186/1423-0127-21-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590224, KAKENHI-PROJECT-26350597
  • [Journal Article] Dimethyl fumarate induces apoptosis of hematopoietic tumor cells via inhibition of NF-κB nuclear translocation and down-regulation of Bcl-xL and XIAP.2014

    • Author(s)
      Tsubaki M, Ogawa N, Takeda T, Sakamoto K, Shimaoka H, Fujita A, Itoh T, Imano M, Satou T, Nishida S.
    • Journal Title

      Biomed Pharmacother.

      Volume: 68 Issue: 8 Pages: 999-1005

    • DOI

      10.1016/j.biopha.2014.09.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Journal Article] Inhibition of the tumour necrosis factor-alpha autocrine loop enhances the sensitivity of multiple myeloma cells to anticancer drugs.2013

    • Author(s)
      Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, Ogawa N, Mashimo K, Fujiwara D, Takeda T, Mukai J, Sakaguchi K, Satou T, Nishida S.
    • Journal Title

      Eur J Cancer.

      Volume: 47 Issue: 17 Pages: 3708-17

    • DOI

      10.1016/j.ejca.2013.07.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Journal Article] Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma cells.2012

    • Author(s)
      Tsubaki M, Satou T, Itoh T, Imano M, Komai M, Nishinobo M, Yamashita M, Yanae M, Yamazoe Y, Nishida S.
    • Journal Title

      Leuk Res.

      Volume: 36 Issue: 10 Pages: 1315-1322

    • DOI

      10.1016/j.leukres.2012.07.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Journal Article] Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK2005

    • Author(s)
      Nishida et al.
    • Journal Title

      Molecular and Cellular Biochemistry 269

      Pages: 109-114

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Apoptosis-inducing effect of mevastatin on various hematopoetic tumor cell lines2004

    • Author(s)
      Nishida et al.
    • Journal Title

      生化学 76

      Pages: 1104-1104

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Diethyldithiocarbamate can induce two different type of death : apoposis and necrosis medating the differential MAP kinase activation and redox regulation in HL60 cells2004

    • Author(s)
      Nishida et al.
    • Journal Title

      Molecular and Cellular Biochemistry 265

      Pages: 123-132

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Diethyldithiocarbamate can induce two different type of death : apoptosis and necrosis mediating the differential MAP kinase activation and redox regulation in HL6O cells2004

    • Author(s)
      Nishida, et al.
    • Journal Title

      Mol Cell Biochem 265

      Pages: 123-132

    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Enhancement of apoptosis-inducing effect by pretreatment of PKC inhibitor2004

    • Author(s)
      Nishida et al.
    • Journal Title

      Cancer Science 95

      Pages: 490-490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Apoptosis-inducing effect of mevastatin on various hematopoetic tumor cell lines2004

    • Author(s)
      Nishida et al.
    • Journal Title

      Seikagaku 76

      Pages: 1104-1104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] C-kinaseそがいによるTNFα壊死効果の増強機序2004

    • Author(s)
      西田升三, その他
    • Journal Title

      Cancer Science(Supplement) 95

      Pages: 469-469

    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Diethyldithiocarbamate can induce two different type of death ; apotosis and necrosis mediating the differential MAP kinase activation2004

    • Author(s)
      Nishida, et al.
    • Journal Title

      生化学 76

      Pages: 1089-1089

    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Apoptosis-inducing effect of mevastatin on various hematopoietic tumor cell lines2004

    • Author(s)
      Nishida, et al.
    • Journal Title

      生化学 76

      Pages: 1104-1104

    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] C-kinase阻害によるTNFα壊死効果の増強機序2004

    • Author(s)
      西田升三, その他
    • Journal Title

      Cancer Science 95

      Pages: 490-490

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Mevastatinによる造血系腫瘍細胞株に対するアポトーシス誘導能2004

    • Author(s)
      西田升三, その他
    • Journal Title

      Cancer Science(Supplement) 95

      Pages: 490-490

    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Pretreatment with PKC inhibitor enhances TNF-alpha induced apoptosis in TNF-alpha resistant cells2003

    • Author(s)
      Nishida et al.
    • Journal Title

      生化学 75

      Pages: 1029-1029

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Pretreatment with PKC inhibitor enhances TNF-alpha induced apoptosis in TNF-alpha resistant cells2003

    • Author(s)
      Nishida et al.
    • Journal Title

      Seikagaku 75

      Pages: 1029-1029

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Journal Article] Pretreatment with PKC inhibitor triggers TNF-alpha induced apoptosis in TNF-alpha-resistant B16 melanoma BL6 cells2003

    • Author(s)
      Nishida et al.
    • Journal Title

      Life Sciences 74

      Pages: 781-792

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14571649
  • [Presentation] Perifosine enhances the sensitivity to oxaliplatin and 5-fluorourasil in PIK3CA-mutated colon cancer.2022

    • Author(s)
      Honoka Takefuji, Masanobu Tsubaki, Tomoya Takeda, Takuya Matsuda, Akihiro Kimura, Shozo Nishida.
    • Organizer
      The 81th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] AT9283 suppresses proliferation in tyrosine kinase inhibitor sensitive and resistant chronic myeloid leukemia cells by inhibition of Aurora A and Aurora B.2022

    • Author(s)
      Tomoya Takeda, Masanobu Tsubaki, Shozo Nishida.
    • Organizer
      The 5rd International Cancer Research Symposium of Training Plan for Oncology Professionals
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] SGK1/NF-NB経路活性化が多発性骨髄腫でのプロテアソーム阻害薬耐性に寄与する.2022

    • Author(s)
      木村 智裕、椿 正寛、武田 朋也、原田 祐希、岸本 真祐子、鶴島 克将、星田 唯史、西田 升三.
    • Organizer
      第72回日本薬学会近畿支部総会・大会
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] HGF/Met/NF-kappaB 経路による骨芽細胞および骨髄間質細胞における RANKL 発現の制御機構.2022

    • Author(s)
      岸本 佳奈、椿 正寛、武田 朋也、松田 拓弥、竹藤 帆花、西田 升三.
    • Organizer
      第26回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] Akt 阻害剤は PIK3CA 変異大腸癌においてオキサリプラチン及び 5-フルオロウラシルの感受性を増大させる2021

    • Author(s)
      森井 悠介、椿 正寛、武田 朋也、松田 拓弥、山本 裕太、岸本 佳奈、西田 升三
    • Organizer
      第25回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] Akt inhibitor enhances the sensitivity to oxaliplatin and 5-fluorourasil in PIK3CA-mutated colon cancer2021

    • Author(s)
      Shozo Nishida, Masanobu Tsubaki, Tomoya Takeda, TakuyaMatsuda, Yuuta Yamamoto, Kana Kishimoto
    • Organizer
      The 80th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] Rhosin suppressed tumor metastasis by inhibition Rho/YAP pathway and expression of RHAMM and CXCR4.2020

    • Author(s)
      Shuji Genno, Masanobu Tsubaki, Tomoya Takeda, Shozo Nishida.
    • Organizer
      The 79th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] Perifosine enhances sensitivity of oxaliplatin and 5-fluorourasil in PIK3CA-mutated colorectal cancer.2020

    • Author(s)
      Yuuta Yamamoto, Masanobu Tsubaki, Tomoya Takeda, Shiori Seki, Shozo Nishida.
    • Organizer
      The 79th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-20K07145
  • [Presentation] 新規NF-kappaB/STAT3 阻害剤による多発性骨髄腫でのアポトーシス誘導機構の解析.2018

    • Author(s)
      小泉 翔太郎, 椿 正寛, 武田 朋也, 浅野 良太, 川島 啓司, 西田 升三.
    • Organizer
      日本薬学会第138回年会
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] MET/ERK and MET/JNK pathways is involved with imatinibresistance in chronic myeloid leukemia.2017

    • Author(s)
      Masanobu Tsubaki, Tomoya Takeda, Yu-ichi Koumoto, Shin-ichiro Fujimoto, Shozo Nishida.
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] Statins によるRas/ERK 及びRas/mTOR 経路阻害を介した造血器系腫瘍でのアポトーシス誘導機序.2017

    • Author(s)
      伊藤 麻祐, 椿 正寛, 武田 朋也, 友成 佳加, 西田 升三.
    • Organizer
      第67回日本薬学会近畿支部総会・大会
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] 多発性骨髄腫でのMIP-1alphaオートクラインは抗がん剤の感受性を低下させ抗がん剤耐性に寄与する.2017

    • Author(s)
      河本 雄一, 椿 正寛, 武田 朋也, 友成 佳加, 浅野 良太, 川島 啓司, 眞下 恵次, 阪口 勝彦, 西田 升三.
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] PioglitazoneはSTAT3阻害を介してSurvivinの発現低下及びAIFの発現増加によりアポトーシスを誘導する.2017

    • Author(s)
      浅野 良太, 椿 正寛, 武田 朋也, 友成 佳加, 藤原 大一朗, 阪口 勝彦, 西田 升三.
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] 慢性骨髄性白血病におけるイマチニブ耐性にMET活性化が関与する2016

    • Author(s)
      椿 正寛、武田 朋也、木野 稔己、友成 佳加、眞下 恵次、藤原 大一朗、藤本 伸一郎、阪口 勝彦、山添 譲、西田 升三.
    • Organizer
      第20回日本がん分子標的治療学会
    • Place of Presentation
      別府国際コンベンションセンター(大分県別府市)
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] MET activation is involved with imatinib-resistance in chronic myeloid leukemia.2016

    • Author(s)
      椿 正寛、武田 朋也、木野 稔己、友成 佳加、藤本 伸一郎、西田 升三.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-15K08116
  • [Presentation] Bisphospohnates及びstatinsによる多発性骨髄腫でのMIP-1α分泌抑制効果2015

    • Author(s)
      椿 正寛、武田 朋也、嶌岡 弘高、坂本 洸太郎、藤田 亜里沙、小川 直希、眞下 恵次、藤原 大一朗、山添 譲、阪口 勝彦、石坂 敏彦、西田 升三
    • Organizer
      日本薬学会 第135年会
    • Place of Presentation
      神戸(神戸学院大学)
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] 造血器腫瘍でのインテグリンを介した抗がん剤耐性機序2014

    • Author(s)
      上田 絵美、椿 正寛、武田 朋也、嶌岡 弘高、坂本 洸太郎、藤田 亜梨沙、西田 升三
    • Organizer
      第64回日本薬学会近畿支部総会・大会
    • Place of Presentation
      京都(京都薬科大学)
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] 多発性骨髄腫での薬剤排泄トランスポーターとアポトーシス調節因子の発現調節を介した抗がん剤耐性機序の解明2014

    • Author(s)
      椿 正寛、武田 朋也、嶌岡 弘高、坂本 洸太郎、藤田 亜梨沙、西田 升三
    • Organizer
      第64回日本薬学会近畿支部総会・大会
    • Place of Presentation
      京都(京都薬科大学)
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] DMF によるNF-κB 阻害を介した造血器腫瘍でのアポトーシス誘導効果2014

    • Author(s)
      橋口 りえ、椿 正寛、武田 朋也、嶌岡 弘高、坂本 洸太郎、藤田 亜梨沙、西田 升三
    • Organizer
      第64回日本薬学会近畿支部総会・大会
    • Place of Presentation
      京都(京都薬科大学)
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] Src 阻害に基づく抗がん剤耐性多発性骨髄腫での耐性克服効果2014

    • Author(s)
      藤田 亜梨沙、椿 正寛、武田 朋也、嶌岡 弘高、坂本 洸太郎、小川 直希、山添 譲、向井 淳治、西田 升三.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] RANK/RANKLによるシグナル伝達因子活性化を介した多発性骨髄腫での抗がん剤耐性獲得機序.2014

    • Author(s)
      椿 正寛、武田 朋也、嶌岡 弘高、坂本 洸太郎、藤田 亜里沙、眞下 恵次、藤原 大一郎、阪口 勝彦、西田 升三.
    • Organizer
      第18回日本がん分子標的治療学会
    • Place of Presentation
      宮城(仙台市情報・産業プラザ(AER) ホテルメトロポリタン仙台 TKPガーデンシティ仙台)
    • Year and Date
      2014-06-27
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] 多発性骨髄腫での抗がん剤多剤耐性獲得機序.2013

    • Author(s)
      駒居 真紀子、椿 正寛、小川 直希、山添 譲、向井 淳治、西田 升三.
    • Organizer
      日本薬学会 第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] MDR1及びsurvivinの過剰発現とBimの発現低下を介した多発性骨髄腫での多剤耐性獲得機序.2012

    • Author(s)
      駒居 真紀子、椿 正寛、小川 直希、山添 譲、向井 淳治、西田 升三.
    • Organizer
      第16回日本がん分子標的治療学会学術集会
    • Place of Presentation
      小倉
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma.2012

    • Author(s)
      駒居 真紀子、椿 正寛、小川 直希、山添 譲、向井 淳治、西田 升三.
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] シグナル伝達因子活性化による多発性骨髄腫での抗がん剤耐性獲得機序.

    • Author(s)
      駒居 真紀子、椿 正寛、嶌岡 弘高、坂本 洸太郎、小川 直希、眞下 恵次、藤原 大一朗、山添 譲、阪口 勝彦、向井 淳治、西田 升三.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] Src阻害を介した多発性骨髄腫での抗がん剤耐性克服機序.

    • Author(s)
      小野 優里、椿 正寛、駒居 真紀子、嶌岡 弘高、坂本 洸太郎、小川 直希、眞下 恵次、藤原 大一朗、向井 淳治、阪口 勝彦、西田 升三.
    • Organizer
      第63回日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学京田辺キャンパス(京都府京田辺市)
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] TNF-alphaオートクライン阻害による抗がん剤殺細胞作用増強効果.

    • Author(s)
      西田 升三、椿 正寛、駒居 真紀子、嶌岡 弘高、坂本 洸太郎、小川 直希、眞下 恵次、藤原 大一朗、山添 譲、阪口 勝彦、向井 淳治.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] 多発性骨髄腫における多剤耐性獲得因子の検討.

    • Author(s)
      駒居 真紀子、椿 正寛、嶌岡 弘高、坂本 洸太郎、小川 直希、眞下 恵次、藤原 大一朗、山添 譲、向井 淳治、阪口 勝彦、西田 升三.
    • Organizer
      第60回日本生化学会近畿支部例会
    • Place of Presentation
      大阪大学吹田キャンパス(大阪府吹田市)
    • Data Source
      KAKENHI-PROJECT-24590224
  • [Presentation] RANK/RANKLによる多発性骨髄腫での抗がん剤耐性獲得機序.

    • Author(s)
      椿 正寛、駒居 真紀子、嶌岡 弘高、坂本 洸太郎、小川 直希、眞下 恵次、藤原 大一朗、山添 譲、向井 淳治、西田 升三.
    • Organizer
      第17回日本がん分子標的治療学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Data Source
      KAKENHI-PROJECT-24590224
  • 1.  TSUBAKI Masanobu (30434856)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 40 results
  • 2.  AKAI Fumiharu (40122006)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  TANEDA Mammoru (10236713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TAKEDA Tomoya (20734031)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 5.  ICHIDA Seiji (00125121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  FUNAKAMI Yoshinori (70449833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  ITOH Tatsuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  SATOU Takao
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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