ISHIDO Kazumi 石堂一巳

… Alternative Names

石堂一巳イシドウカズミ

ISHIDOU Kazumi 石堂一巳

ISHIDOH Kazumi 石堂一巳

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Researcher Number	40212906
Other IDs
External Links
Affiliation (Current)	2025: 徳島文理大学, 大学共同利用機関等の部局等, 教授
Affiliation (based on the past Project Information) *help	2011: 徳島文理大学, 健康科学研究所, 教授 2006: 徳島文理大学, 健康科学研所, 教授 2005 – 2006: 徳島文理大学, 健康科学研究所, 教授 2004 – 2005: 徳島文理大学, 健康科学研究所・分子生物学部門, 教授 2003: Tokushima Bunri Univ., Health Science Institute, Professor, 健康科学研究所, 教授 … More 2002 – 2003: 順天堂大学, 医学部, 講師 1998 – 2000: Juntendo University, Biochemistry I,Assistant Professor, 医学部, 講師 1995 – 1997: 順天堂大学, 医学部, 助手 1990 – 1993: 順天堂大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry Except Principal Investigator Dermatology / Pathological medical chemistry / Experimental pathology / 代謝生物化学 / Pathological medical chemistry / Applied health science
Keywords	Principal Investigator LDH-A / リソソーム / platelet derived growth factor receptor / epidermal growth factor receptor / insulin receptor / ubiquitin / protein degradation / lysosome / c-Cbl / マルチユビキチン化 … More / ポリユビキチン化 / ユビキチン / 血小板由来増殖因子受容体 / 上皮性増殖因子受容体 / インスリン受容体 / ユビキチン化 / タンパク質分解 / Bafilomycin A1 / Processing / Legumain / Cathepsin / Lysosomes / プロカテプシン / バフィロマイシンA1 / プロセッシング / レグマイン / バフィロマイシンAl / カテプシン … More Except Principal Investigator cell cycle / ELISA / Transforming growth factor-beta / Procollagen mRNA / Silica / ep / Pale ear / HPS-1 / Hermansky-Pudlak syndrome / cyclin / proteasome / keratinazation / keratinocyte / psoriasis / 表皮細胞 / ケラチノサイト / 細胞周期 / サイクリン / プロテアソーム / 分化 / 乾癬 / beta-COP / coated vesicle / lgp120 / PCR / adaptin / lysosome / 免疫測定法 / Monoclonal antibody / phage display method / Immunoassay / Hapten / 内分泌撹乱物質 / 分析化学 / 酵素 / 抗体 / モノクローナル抗体 / ファージディスプレイ / ハプテン / 胎児線維芽細胞株 / 免疫電顕 / Lysosome / Cathepsin L / ep遺伝子 / Hermansky-Pudlak症候群 / TGF-beta / Real time RT-PCR / 胎児線維芽細胞 / Procollagen mRNAs / 肺線維症 / プロテアーム / 病像形成 / プロテアーゼ / coat protein / リソゾーム膜蛋白質 / リソゾーム / β-COP / Alzhieimer's disease / Degeneration / Neuron / Bone resorption / Cathepsin / Proteinase / Lysosomes / アルツハイマ-病 / 変性 / 神経細胞 / 骨吸収 / カテプシン / プロテア-ゼ / リソゾ-ム / リスク評価 / 早期腎障害 / 運動・栄養指導 / アセスメント / 尿 / 運動指導 / 栄養指導 / 機能性食品 / リスクプロファイリング / バイオマーカー / 生理活性物質 / 早期診断 / 糖尿病 Less

Development of a diabetes risk profile using a urinary biomarker and its application in the assessment of nutrient status and exercise levels.
- Principal Investigator
  
  HASHIDA Seiichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Tokushima Bunri University
Development of "heterocapture sandwich EIA" and detection of the a hormone-disrupting substance
- Principal Investigator
  
  HASHIDA Seiichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokushima Bunri University
The function of ubiquitin in intralysosomal protein degradation.Principal Investigator
- Principal Investigator
  
  ISHIDOH Kazumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokushima Bunri University
Analysis for the function of murine lung fibrosis-related gene, ep
- Principal Investigator
  
  KUMASAKA Toshio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  JUNTENDO UNIVERSITY
The Mechanisms in activation and secretion of procathepsin L in accordance with transformationPrincipal Investigator
- Principal Investigator
  
  ISHIDOH Kazumi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  JUNTENDO UNIVERSITY
The role of protease in pathogenesis of psoriasis
- Principal Investigator
  
  TAKAMORI Kenji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Juntendo University
The role of protease in pathogenesis of psoriasis
- Principal Investigator
  
  TAKAMORI Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Juntendo University
The role of beta-COP like membrane protein in lysosome formation
- Principal Investigator
  
  EZAKI Junji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Juntendo University School of Medicine
Involvement of Lysosomal Cysteine Proteinases in Bone Resorption and Nerve Cells
- Principal Investigator
  
  KOMINAMI Eiki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Juntendo University School of Medicine

All 2011 2010 2009 2006 2005 2004 Other

All Journal Article Book

[Book] 癌転移とプロテアーゼinプロセテーゼインヒビター臨床編2005
- Author(s)
  石堂一巳
- Total Pages
  271
- Publisher
  診断と治療社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Book] 癌転移とプロテアーゼプロテアーゼインヒビター臨床編2005
- Author(s)
  石堂一巳
- Total Pages
  271
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Hybrid exercise prevents muscle atrophy in association with a distinct gene expression pattern2011
- Author(s)
  Matsugaki T, Shiba N, Kohno S, Nikawa T, Hirasaka K, Okumura Y, Ishidoh K, Soejima T, Yoshimitsu K, Nagata K.
- Journal Title
  
  Kurume Med J
  
  Volume: 57(4) Pages: 101-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500701
[Journal Article] Nobuhiko Katunuma : An Outstanding Scientist in the field of Proteolysis and Warm-Hearted' Kendo Fighter' Biochemist2010
- Author(s)
  Kido, H and Ishidoh K
- Journal Title
  
  J. Biochem
  
  Volume: 148 Pages: 527-531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500701
[Journal Article] Quinolinate Phosphoribosyl Transferase. a key enzyme in de novo NAD+synthesis, suppress spontenous cell death by inhibiting overproduction of active-caspase-32010
- Author(s)
  Ishidoh K, Kamemura N, Imagawa T, Oda M, Sakurai J, Katunuma N
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1803 Pages: 527-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500701
[Journal Article] Ubiquitin ligase Cbl-b is a negative regulator for IGF-1 signaling during muscle atrophy caused by unloading2009
- Author(s)
  Nakao R, Hirasaka K, Goto J, Ishidoh K, Yamada C, Ohno A, Okumura Y, Nonaka I, Yasutomo K, Baldwin KM, Kominami E, Higashibata A, Nagano K, Tanaka K, Yasui N, Mills EM, Takeda S, Nikawa T.
- Journal Title
  
  MolCell Biol
  
  Volume: 29(17) Pages: 4798-4811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500701
[Journal Article] Inhibition of collagenolytic cathepsins by beta-lactoglobulin in milk and its suppressive effect on bone resorption2009
- Author(s)
  Ogawa N, Takahashi M, Ishidoh K, Katunuma N.
- Journal Title
  
  J Nutr Sci Vitaminol
  
  Volume: 55(3) Pages: 264-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500701
[Journal Article] Ubiquitin ligase gene expression in healthy volunteers with 20-day bed rest.2006
- Author(s)
  Ogawa T, Furochi H, Mameoka M, Hirasaka K, Onishi Y, Suzue N, Oarada M, Akamatsu M, Akima H, Fukunaga T, Kishi K, Yasui N, Ishidoh K, Fukuoka H, Nikawa T.
- Journal Title
  
  Muscle Nerve 34
  
  Pages: 463-469
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590281
[Journal Article] Ubiquitinligase Cbl-b downregulates bone formation through suppression of IGF-I signaling in osteoblasts during denervation.2006
- Author(s)
  Suzue N, Nikawa T, Onishi Y, Yamada C, Hirasaka K, Ogawa T, Furochi H, Kosaka H, Ishidoh K, Gu H, Takeda S, Ishimaru N, Hayashi Y, Yamamoto H, Kishi K, Yasui N.
- Journal Title
  
  J.Bone Mineral Res. 21
  
  Pages: 722-734
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590281
[Journal Article] Microarrayanalysis identified differentially expressed genes in keratocytes from keratocounus patients.2005
- Author(s)
  Ha N.T., Nakayasu, K., Murakami, A., Ishidoh K., Kanai A.
- Journal Title
  
  Curr.Eye Res. 28
  
  Pages: 373-379
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes.2005
- Author(s)
  Nakano N, Nakao, A.Ishidoh, K., Kominami, E., Tsuboi, R., Ogawa, H.
- Journal Title
  
  Br.J.Dermatol. 153
  
  Pages: 37-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Identification of mono-ubiquitinated LDH-A in skeletal muscle cells exposed to oxidative stress.2005
- Author(s)
  Onishi Y, Hirasaka K, Ishihara I, Oarada M, Goto J, Ogawa T, Suzue N, Nakano S, Furochi H, Ishidoh K, Kishi K, Nikawa T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 336
  
  Pages: 799-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Gene expression profiles in response to Fas stimulation in Trypanosoma cruzi-infected host cells.2005
- Author(s)
  Hashimoto M, Nakajima-Shimada J, Ishidoh K, Aoki T.
- Journal Title
  
  Int.J.Parasitol. 25
  
  Pages: 1587-1594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Inflammatory response and cathepsins in silica-exposed Hermansky-Pudlak syndrome model pale ear mice.2004
- Author(s)
  Yoshioka Y, Kumasaka T, Ishidoh K, Kominami E, Mitani K, Hosokawa Y, Fukuchi Y
- Journal Title
  
  Pathology International 54
  
  Pages: 322-331
- NAID
  10016542813
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570200
[Journal Article] Inflammatory response and cathepsins in silica-exposed Hermansky-Pudlock syndrome medel pale year mice.2004
- Author(s)
  Yoshioka, Y., Kumasaka, T., Ishidoh, K., Kominami, E., Mitani, K., Hosokawa, Y., Fukuchi, Y.
- Journal Title
  
  Pathology Int. 54
  
  Pages: 322-331
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Microarray analysis identified differentially expressed genes in keratocytes from keratocounus patients.2004
- Author(s)
  Ha, NT, Nakayasu, K, Murakami, A, Ishidoh, K, Kanai, A
- Journal Title
  
  Curr.Eye Research 28
  
  Pages: 373-379
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and a3 integrin.2004
- Author(s)
  Reiser J, Oh J, Shirato I, Asanuma K, Hug A, Mundel TM, Honey K, Ishidoh K, Kominami E, Kreidberg JA, Tomino Y, Mundel P.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 34827-34832
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] 糖尿病とタンパク質のユビキチン化2004
- Author(s)
  石堂一巳
- Journal Title
  
  内分泌・糖尿病化 18・4
  
  Pages: 352-357
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Epidermal growth factor activates m-calpain, resulting in apoptosis in HaCaT keratinocytes.2004
- Author(s)
  Inoue, A., Yamazaki, M., Ishidoh, K., Ogawa, H.
- Journal Title
  
  J.Dermatol Sci. 36
  
  Pages: 60-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Analysis on which types of proteinases participate in processing and activation of prolegumain in primary cultured rat macrophages.2004
- Author(s)
  Lecaille, F., Muno, D., Kominami, E., Ishidoh, K.
- Journal Title
  
  Biol.Chem. 385
  
  Pages: 511-516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Analysis on which types of proteinases participate in processing and activation of prolegumain in primary cultured rat macrophages.2004
- Author(s)
  Lecaille, F, Muno, D, Kominami, E., Ishidoh K
- Journal Title
  
  Biol Chem 385
  
  Pages: 511-516
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Inflammatory response and cathepsins in silica-exposed Hermansky-Pudlak syndrome model pale ear mice.2004
- Author(s)
  Yoshioka Y, Kumasaka T, Ishidoh K, et al.
- Journal Title
  
  Pathology International 57
  
  Pages: 322-331
- NAID
  10016542813
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570200
[Journal Article] Skeltal muscle gene expression in space-flown rats.2004
- Author(s)
  Nikawa, T., Ishidoh, K., Hirasaka, K., Ishihara, K., Ikemoto, M., Kano, K., Kominami, E., NOnaka, I., Ogawa, T., Adam, G.R., Baldwin, K.M., Yasui, N., Kishi, K., Takeda, S.
- Journal Title
  
  FASEB.J. 18
  
  Pages: 522-524
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Skeltal muscle gene expression in space-flown rats.2004
- Author(s)
  NIkawa, T, Ishidoh, K, Hirasaka, K, Ishihara, K, (他10名)
- Journal Title
  
  FASEB J 18
  
  Pages: 522-524
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.2004
- Author(s)
  Fujita, H., Umezaki, Y., Imamura, K., Ishikawa, D., Uchimura, S., Nara, A., Yoshimori, T., Hayashizaki, Y., Kawai, J., Ishidoh, K., Tanaka Y., Himeno, M.
- Journal Title
  
  J.Cell Sci. 117
  
  Pages: 2997-3009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes
- Author(s)
  Nakano, N, Nakao, A, Murakami, A, Ishidoh K, (他3名)
- Journal Title
  
  Br.J.Dermatol in press
- Data Source
  KAKENHI-PROJECT-16590235
[Journal Article] Ubiquitin ligase Cbl-b downregulates bone formation through suppression of IGF-I signaling in osteoblasts during denervation.
- Author(s)
  Suzue N, Nikawa T, Onishi Y, Yamada, C, Hirasaka K, Ogawa T, Furochi H, Kosaka H, Ishidoh K, Gu H, Takeda S, Ishimaru N, Hayashi Y, Yamamoto H, Kishi K, Yasui N
- Journal Title
  
  J.Bone Mineral Res. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590235

1. HASHIDA Seiichi (10156268)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TAKAMORI Kenji (40053144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. UMEHARA Asako (60441599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KOMINAMI Eiki (10035496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KATUNUMA Nobuhiko (50035375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. EZAKI Junji (60232948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUGA Yasushi (90245738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUMASAKA Toshio (00286709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

ISHIDO Kazumi 石堂 一巳

石堂 一巳 イシドウ カズミ

ISHIDOU Kazumi 石堂 一巳

ISHIDOH Kazumi 石堂 一巳

Research Projects

Research Products

Co-Researchers

Development of a diabetes risk profile using a urinary biomarker and its application in the assessment of nutrient status and exercise levels.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of "heterocapture sandwich EIA" and detection of the a hormone-disrupting substance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The function of ubiquitin in intralysosomal protein degradation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis for the function of murine lung fibrosis-related gene, ep

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Mechanisms in activation and secretion of procathepsin L in accordance with transformationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of protease in pathogenesis of psoriasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of protease in pathogenesis of psoriasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of beta-COP like membrane protein in lysosome formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of Lysosomal Cysteine Proteinases in Bone Resorption and Nerve Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 癌転移とプロテアーゼinプロセテーゼインヒビター臨床編2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 癌転移とプロテアーゼ プロテアーゼインヒビター臨床編2005

Author(s)

Total Pages

Data Source

[Journal Article] Hybrid exercise prevents muscle atrophy in association with a distinct gene expression pattern2011

Author(s)

Journal Title

Data Source

[Journal Article] Nobuhiko Katunuma : An Outstanding Scientist in the field of Proteolysis and Warm-Hearted' Kendo Fighter' Biochemist2010

Author(s)

Journal Title

Data Source

[Journal Article] Quinolinate Phosphoribosyl Transferase. a key enzyme in de novo NAD+synthesis, suppress spontenous cell death by inhibiting overproduction of active-caspase-32010

ISHIDO Kazumi 石堂一巳

石堂一巳イシドウカズミ

ISHIDOU Kazumi 石堂一巳

ISHIDOH Kazumi 石堂一巳

[Book] 癌転移とプロテアーゼプロテアーゼインヒビター臨床編2005