SEKI Naoko 関直子

… Alternative Names

関直子セキナオコ

Less

Researcher Number	40226634
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2010 – 2016: 久留米大学, 医学部, 講師 2007 – 2011: Kurume University, 医学部, 助教 2005 – 2006: 久留米大学, 医学部, 助手 1998 – 2000: 久留米大学, 医学部, 助手 1996: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General surgery / Digestive surgery / Orthopaedic surgery / Digestive surgery Except Principal Investigator Digestive surgery / General surgery / Digestive surgery
Keywords	Principal Investigator 癌 / 免疫 / 免疫学 / 乳癌 / 乳腺外科学 / Immunology / Cancer / 日本人 / HLA / リウマチ性疾患 … More / 遺伝子多型 / プロモーター遺伝子 / TNF-α / 癌局所浸潤リンパ球 / ペプチド抗原 / 腺癌 / HLA拘束性 / 細胞傷害性キラーT細胞 / 癌退縮抗原 … More Except Principal Investigator HLA / SART-3 / SART-2 / SART-1 / CTL / cancer vaccine / tumor rejection antigen / gastric cancer / 癌ワクチン / 癌拒絶抗原 / 胃癌 / ペプチドワクチン療法 / 癌免疫療法 / 乳癌 / がん免疫療法 / がんペプチドワクチン / ペプチドワクチン / がんﾍﾟﾌﾟﾁﾄﾞﾜｸﾁﾝ / 乳がん / 相乗効果 / 難治性腫瘍 / 免疫細胞療法 / Bortezomib / Trastuzumab / 難治性がん / 化学療法 / 細胞免疫療法 / 日本人 / 癌免疫治療 / 遺伝子多型 / プロモーター遺伝子 / TNF-α Less

癌・免疫のクロストーク機構および免疫バイオマーカー解析による乳癌治療戦略の検討Principal Investigator
- Principal Investigator
  
  関直子
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Study of immunosuppressive tumor microenvironment and therapeutic strategy in breast cancerPrincipal Investigator
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Clinical feasibility of personalized peptide vaccination for metastatic breast cancer patients
- Principal Investigator
  
  TOH Uhi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Immunological study of HER2+breast cancer-study of strategy for effective cancer-immunotherapyPrincipal Investigator
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
The combination effects of conventional chemotherapy and adoptive cell therapy for refractory advanced/recurrent cancer
- Principal Investigator
  
  TOH Uhi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University
Immunological effects of the treatment with anti-tumor monoclonal antibody in breast cancer patientsPrincipal Investigator
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Study on anti-tumor effects of IL-18-analysis of IL-18 transgenic mouse with CD11b promoter genePrincipal Investigator
- Principal Investigator
  
  SEKI Naoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University
日本人におけるTNF-αプロモーター遺伝子変異の臨床的意義(癌患者免疫治療予後予測マーカーの可能性)
- Principal Investigator
  
  新谷文彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University
日本人・リウマチ性疾患患者における新規のTNF-αプロモーター遺伝子多型の解析Principal Investigator
- Principal Investigator
  
  関直子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
Identification of a gene coding for a gastric caicinoman an tigen and develop of a pepticle vaecinefor the tieatment o patnents gostrica
- Principal Investigator
  
  SHIIBA Ken-ichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
HLA-A2拘束性腺癌特異的癌退縮抗原遺伝子のクローニングPrincipal Investigator
- Principal Investigator
  
  関直子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kurume University

All 2017 2014 2013 2012 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Predictive factors of the tumor immunological microenvironment for long-term follow-up in early stage breast cancer.2017
- Author(s)
  Okabe M, Toh U, Iwakuma N, Saku S, Akashi M, Kimitsuki Y, Seki N, Kawahara A, Ogo E, Itoh K, Akagi Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 1 Pages: 81-90
- DOI
  10.1111/cas.13114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10078, KAKENHI-PROJECT-26461965
[Journal Article] Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients.2014
- Author(s)
  Takahashi R, Toh U, Iwakuma N, Takenaka M, Otsuka H, Furukawa M, Fujii T, Seki N, Kawahara A, Kage M, Matsueda S, Akagi Y, Yamada A, Itoh K, Sasada T.
- Journal Title
  
  Breast Cancer Res.
  
  Volume: 16 Issue: 4 Pages: 00-00
- DOI
  10.1186/bcr3685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591914, KAKENHI-PROJECT-24591925, KAKENHI-PROJECT-26293293, KAKENHI-PROJECT-26430176, KAKENHI-PROJECT-26461965
[Journal Article] FOXP3 expression in tumor cells and tumor-infiltrating lymphocytes is associated with breast cancer prognosis2013
- Author(s)
  Miki Takenaka, Naoko Seki, Uhi Toh, Satoshi Hattori, Akihiko Kawahara, Tomohiko Yamaguchi, Keiko Koura, Ryuji Takahashi, Hiroko Otsuka, Hiroki Takahashi, Nobutaka Iwakuma, Shino Nakagawa, Teruhiko Fujii, Tetsuro Sasada, Rin Yamaguchi, Hirohisa Yano, Kazuo Shirouzu, Masayoshi Kage
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 1 Issue: 4 Pages: 625-632
- DOI
  10.3892/mco.2013.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591912, KAKENHI-PROJECT-23790425, KAKENHI-PROJECT-24591925
[Journal Article] Treatment outcome in patients with stage III breast cancer treated with neoadjuvant chemotherapy.2013
- Author(s)
  Takahashi R, Toh U, Iwakuma N, Mishima M, Fujii T, Takenaka M, Koura K, Seki N, Kawahara A, Kage M, Ogo E, Shirouzu K
- Journal Title
  
  Exp Ther Med
  
  Volume: 6 Pages: 1089-1095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591925
[Journal Article] Treatment outcome in patients with stage III breast cancer treated with neoadjuvant chemotherapy2013
- Author(s)
  Takahashi R, Toh U, Iwakuma N, Mishima M, Fujii T, Takenaka M, Koura K, Seki N, Kawahara A, Kage M, Ogo E, Shirouzu K.
- Journal Title
  
  Exp Ther Med.
  
  Volume: 6 (5) Pages: 1089-1095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591914
[Journal Article] FOXP3 expression in tumor cells and tumor-infiltrating lymphocytes is associated with breast cancer prognosis.2013
- Author(s)
  Takenaka M, Seki N, Toh U, Hattori S, Kawahara A, Yamaguchi T, Koura K, Takahashi R, Otsuka H, Takahashi H, Iwakuma N, Nakagawa S, Fujii T, Sasada T, Yamaguchi R, Yano H, Shirouzu K, Kage M
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 1(4) Pages: 625-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591914
[Journal Article] Tricin inhibits proliferation of human hepatic stellate cells in vitro by blocking tyrosine phosphorylation of PDGF receptor and its signaling pathways2012
- Author(s)
  N Seki, U Toh, K Kawaguchi, M Ninomiya, M Koketsu, K Watanabe, M Aoki, T Fujii, A Nakamura, Y Akagi, J Kusukawa, M Kage, K Shirouzu and H Yamana
- Journal Title
  
  J Cell Biochem
  
  Volume: (in press) Issue: 7 Pages: 2346-55
- DOI
  10.1002/jcb.24107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792044, KAKENHI-PROJECT-23591914
[Journal Article] Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways.2010
- Author(s)
  Seki N, Toh U, Sayers TJ, Fujii T, Miyagi M, Akagi Y, Kusukawa J, Kage M, Shirouzu K, Yamana H.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 9(6) Pages: 1842-1851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591581
[Journal Article] Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways.2010
- Author(s)
  Seki N, Toh U, Sayers TJ, Fujii T, Miyagi M, Akagi Y, Kusukawa J, Kage M, Shirouzu K, Yamana H.
- Journal Title
  
  Mol Cancer Ther. 9(6)
  
  Pages: 1842-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591581
[Journal Article] YB-1 prevents apoptosis via the mTOR/STAT3 pathway in HER-2-overexpressing breast cancer cells.2009
- Author(s)
  Fujii T, Seki N, Takahashi H, Inoue Y, Toh U, Kage M, Shirouzu K.
- Journal Title
  
  Future Oncol. 5(2)
  
  Pages: 153-6
- Data Source
  KAKENHI-PROJECT-20591581
[Journal Article] YB-1 prevents apoptosis via the mTOR/STAT3 pathway in HER-2-overexpressing breast cancer cells2009
- Author(s)
  Fujii T, Seki N, Namoto-Matsubayashi R, Takahashi H, Inoue Y, Toh U, Kage M, Shirouzu K.
- Journal Title
  
  Future Oncol. 5・2
  
  Pages: 153-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591581
[Journal Article] 難治性再発乳癌に対するtrastuzumab併用細胞免疫療法2008
- Author(s)
  三島麻衣, 唐宇飛, 山名秀明, 関直子, 他
- Journal Title
  
  Biotherapy 22(5)
  
  Pages: 322-326
- Data Source
  KAKENHI-PROJECT-20591581
[Journal Article] Characterization of IL-2-activated TILs and their use in intrapericardial immunotherapy in malignant pericardial effusion2006
- Author(s)
  Toh U, Fujii T, Seki N, Niiya F, Shirouzu K, Yamana H.
- Journal Title
  
  Cancer Immunol Immunother Dec16
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-17591450
[Journal Article] Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L.2005
- Author(s)
  Lee JK, Seki N, Sayers TJ, Subleski J, Gruys EM, Murphy WJ, Wiltrout RH
- Journal Title
  
  Cell Immunol 235(2)
  
  Pages: 145-52
- Data Source
  KAKENHI-PROJECT-17591450
[Journal Article] Constitutive expression of functional CD40 on mouse renal cancer cells : induction of Fas and Fas-mediated killing by CD40L.2005
- Author(s)
  Lee JK, Seki N, Sayers TJ, Subleski J, Gruys EM, Murphy WJ, Wiltrout RH.
- Journal Title
  
  Cell Immunol. 235(2)
  
  Pages: 145-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591450
[Journal Article] Characterization of IL-2-activated TILs and their use in intrapericardial immunotherapy in malignant pericardial effusion2005
- Author(s)
  Toh U, Fujii T, Seki N, Niiya F, Shirouzu K, Yamana H
- Journal Title
  
  Cancer Immunol Immunother 55 (10)
  
  Pages: 1219-1227
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591450
[Journal Article] Constitutive expression of functional CD40 on mouse renal cancer cells : induction of Fas and Fas-mediated killing by CD40L.2005
- Author(s)
  Lee JK, Seki N, Sayers TJ, Subleski J, Gruys EM, Murphy WJ, Wiltrout RH
- Journal Title
  
  Cell Immunol 235 (2)
  
  Pages: 145-152
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591450
[Journal Article] Characterization of IL-2-activated TILs and their use in intrapericardial immunotherapy in malignant pericardial effusion2005
- Author(s)
  Toh U, Fujii T, Seki N, Niiya F, Shirouzu K, Yamana H.
- Journal Title
  
  Cancer Immunol Immunother. 55(10)
  
  Pages: 1219-1227
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591450
[Presentation] 乳癌におけるCancer/Testis Antigens発現に関する免疫組織学的検討2014
- Author(s)
  竹中　美貴、　関　直子　et al.
- Organizer
  第22回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24591925
[Presentation] Expression of cancer-testis antigens in breast cancer2012
- Author(s)
  関直子
- Organizer
  8^<th> European Breast Cancer Conference
- Place of Presentation
  Vienna, Austria
- Year and Date
  2012-03-22
- Data Source
  KAKENHI-PROJECT-21591685
[Presentation] FOXP3 expressions in both tumor cells and tumor infiltrating lymphocytes are associated with the prognosis in breast cancer patients2012
- Author(s)
  竹中美貴、関直子、唐宇飛, 他
- Organizer
  8^<th> European Breast Cancer Conference
- Place of Presentation
  Vienna, Austria
- Year and Date
  2012-03-22
- Data Source
  KAKENHI-PROJECT-21591685
[Presentation] Strategy to Augment the Efficacy of Immunotherapy For Refractory Breast Cancer : a Pilot Clinical Study of Adoptive Cell Therapy Combined with Trastuzumab2010
- Author(s)
  関直子
- Organizer
  7th European Breast Cancer Conference
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2010-03-24
- Data Source
  KAKENHI-PROJECT-21591685
[Presentation] 乳癌組織におけるFOXP3とpSTAT3の発現についての検討2010
- Author(s)
  関直子、唐宇飛, 他
- Organizer
  第23回日本バイオセラピィ学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591685
[Presentation] 乳癌組織におけるFOXP3とpSTAT3の発現についての検討2010
- Author(s)
  竹中美貴、唐宇飛、関直子、岩熊伸高、大塚弘子、白水和雄、山名秀明、鹿毛政義
- Organizer
  第23回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] 基礎解析から見た治療耐性進行再発癌に対する細胞免疫療法を含めた集学的治療の可能性2009
- Author(s)
  唐宇飛、関直子、福永真理、福嶋敬愛、三島麻衣、山名秀明、白水和雄
- Organizer
  第109回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] Strategy to augment the efficacy of immunotherapy for refractory breast cancer : a pilot clinical study of adoptive cell therapy combined with trastuzumab2009
- Author(s)
  N Seki, U Toh, T.Fujii, S Nagagawa, K Shirouzu, H Yamana
- Organizer
  European Breast Cancer Conference 7
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] Strategy to augment the efficacy of immunotherapy for refractory breast cancer using trastuzumab combined adoptive cell therapy.2008
- Author(s)
  Toh U, Fujii T, Seki N, etc.
- Organizer
  2008 ASCO (The American Society of Clinical Oncology) Annual Meeting
- Place of Presentation
  Chicago, USA.
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] Trastuzumabによる腫瘍特異的細胞性免疫の誘導2008
- Author(s)
  唐宇飛、関直子、山名秀明、白水和雄
- Organizer
  第21回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] Strategy to Augment the Efficacy of Immunotherapy for Refractory Breast Cancer : a Pilot Clinical Study of Adoptive Cell Therapy Combined with Trastuzumab2008
- Author(s)
  N. Seki
- Organizer
  AACR Special Conference-Tumor Immunology: New Perspectives conference
- Place of Presentation
  Miami, FL, U.S.A.
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] プロテアソーム阻害薬によるTRAIL感受性の増強効果2008
- Author(s)
  唐宇飛、藤井輝彦、白水和雄、関直子、山名秀明
- Organizer
  第29回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] Strategy to Augment the Efficacy of Immunotherapy For Refractory Breast Cancer : a Pilot Clinical Study of Adoptive Cell Therapy Combined with Trastuzumab2008
- Author(s)
  Naoko Seki
- Organizer
  AACR Special Conference - Tumor Immunology : New Perspectives conference
- Place of Presentation
  Miami, FL, U.S.A.
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] 難治性乳癌の抗体治療薬併用細胞免疫療法に関する検討2008
- Author(s)
  福嶋敬愛、唐宇飛、三島麻衣、福永真理、白水和雄、関直子、山名秀明
- Organizer
  第21回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20591581
[Presentation] Trastuzumabにより誘導される腫瘍特異的細胞性免疫2008
- Author(s)
  関直子
- Organizer
  第29回癌免疫外科研究会・ワークショップ
- Place of Presentation
  東京
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] Strategy to augment the efficacy of immunotherapy for refractory breast cancer using trastuzumab combined adoptive cell therapy.2008
- Author(s)
  U. Toh, T. Fujii, N. Seki, S. Nakagawa, M. Mishima, M. Fukunaga, E. Ogo, T. Yahara, H. Yamana, K. Shirouzu
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago, IL, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] Combination of gemcitabine and adoptive cell therapy of autologous anti-tumor CTL induces clinical activities in patients with refractory lung cancer.2007
- Author(s)
  U. Toh, T. Fujii, S. Takamori, M. Fukunaga, E. Ogo, N. Seki, H. Yamana, K. Shirouzu
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago, IL, U.S.A.
- Data Source
  KAKENHI-PROJECT-19591524
[Presentation] 乳癌の免疫腫瘍抗原を治療ターゲットとしたトランスレーションリサーチ－基礎実験から臨床研究へ－
- Author(s)
  唐　宇飛、関　直子、竹中美貴、高橋龍司、岩熊伸高、三島麻衣、藤井輝彦、笹田哲朗、伊東恭悟、白水和雄
- Organizer
  第22回日本乳癌学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-10 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-23591914
[Presentation] 乳癌組織におけるCancer/testis antigens発現についての検討
- Author(s)
  竹中美貴、唐　宇飛、関　直子、河原明彦、服部　聡、高良慶子、高橋龍司、大塚弘子、三島麻衣、岩熊伸高、山口　倫、矢野博久、白水和雄、鹿毛政義
- Organizer
  第51回九州外科学会
- Place of Presentation
  北九州
- Year and Date
  2014-05-09 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-23591914

1. TOH Uhi (60268901)

# of Collaborated Projects: 7 results

# of Collaborated Products: 26 results
2. FUJII Teruhiko (50199288)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. YAMANA Hideaki (30140669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. KAGE Masayoshi (80148840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 新谷文彦 (10289449)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 神薗慎太郎 (30261077)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KOMATSU Nobukazu (50343687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHIIBA Ken-ichi (90196345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MATSUNO Seiki (80004737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIZOI Takayuki (90271949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHICHIJO Shigeki (30080592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HOHINO Tomoaki (00261066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AOKI Masatora

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 岩熊伸高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SEKI Naoko 関 直子

関 直子 セキ ナオコ

Research Projects

Research Products

Co-Researchers

癌・免疫のクロストーク機構および免疫バイオマーカー解析による乳癌治療戦略の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of immunosuppressive tumor microenvironment and therapeutic strategy in breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical feasibility of personalized peptide vaccination for metastatic breast cancer patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological study of HER2+breast cancer-study of strategy for effective cancer-immunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The combination effects of conventional chemotherapy and adoptive cell therapy for refractory advanced/recurrent cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological effects of the treatment with anti-tumor monoclonal antibody in breast cancer patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on anti-tumor effects of IL-18-analysis of IL-18 transgenic mouse with CD11b promoter genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

日本人におけるTNF-αプロモーター遺伝子変異の臨床的意義(癌患者免疫治療予後予測マーカーの可能性)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

日本人・リウマチ性疾患患者における新規のTNF-αプロモーター遺伝子多型の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a gene coding for a gastric caicinoman an tigen and develop of a pepticle vaecinefor the tieatment o patnents gostrica

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HLA-A2拘束性腺癌特異的癌退縮抗原遺伝子のクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Predictive factors of the tumor immunological microenvironment for long-term follow-up in early stage breast cancer.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients.2014

Author(s)

Journal Title

DOI

SEKI Naoko 関直子

関直子セキナオコ