YAMAMOTO Shoji 山元昭二

Researcher Number	40230552
Affiliation (based on the past Project Information) *help	2009: 国立環境研究所, 高感受性影響研究室, 主任研究員 2007 – 2009: National Institute for Environmental Studies, 環境リスク研究センター, 主任研究員 2007 – 2008: 独立行政法人国立環境研究所, 環境リスクセンター, 主任研究員
Review Section/Research Field	Principal Investigator Hygiene Except Principal Investigator Environmental impact assessment/Environmental policy / Hygiene
Keywords	Principal Investigator 有害化学物質 / 免疫学 / 細菌 / 感染症 / アレルギー / 小児健康影響 / 環境生理 Except Principal Investigator 感染実験 / 微生物 / サイトカン・ケモカイン … More / 好中球 / 敗血症 / 感染症 / 肺の炎症 / 肺の炎症増悪 / 遺伝子解析 / 炎症性サイトカイン / Bacillus sp / 肺炎桿菌 / 付着微生物 / 黄砂 / マウス / 肺線維症 / アスベスト Less

黄砂感染症の健康影響評価を目指した実験的パイロットスタディ
- Principal Investigator
  
  市瀬孝道
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental impact assessment/Environmental policy
- Research Institution
  Oita University of Nursing and Health Sciences
Study on the acute inflammatory effect of indigenous bacterium on lung asbestosis
- Principal Investigator
  
  HIYOSHI Kyoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  University of Shizuoka
The effect of exposure to chemical substance with bacterial toxin on the development of Th1/Th2 balance in infant mice.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Shoji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  National Institute for Environmental Studies

All 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Up-regulation of neurotrophin-related gene expression in mouse hippocampus following low-level toluene exposure2010
- Author(s)
  in-Shwe, T.T., Tsukahara, S., Yamamoto, S., Fukushima, A., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  Neuro. Toxicol. 31(1)
  
  Pages: 85-93
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] 揮発性有機化合物の胎仔期曝露による仔マウスのTh1, Th2型免疫応答のかく乱2010
- Author(s)
  山元昭二・Tin-Tin-Win-Shwe・藤巻秀和
- Journal Title
  
  岡山実験動物研究会報誌 26
  
  Pages: 45-49
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] 揮発性有機化合物の胎仔期曝露による仔マウスのTh1, Th2型免疫応答のかく乱2010
- Author(s)
  山元昭二・Tin-Tin Win-Shwe・藤巻秀和
- Journal Title
  
  岡山実験動物研究会報誌 26
  
  Pages: 45-49
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Suppression of Th1- and Th2- type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan2009
- Author(s)
  Yamamoto, S., Win-Shwe, T.T., Yoshida, Y., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  Inhal.Toxicol. 21
  
  Pages: 793-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Modulation of systemic Th1/Th2 immune response in infant mice after prenatal exposure to low-level toluene and toll-like receptor(TLR)2 ligand2009
- Author(s)
  Yamamoto, S., Win-Shwe, T.T., Yoshida, Y., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  J.Toxicol.Sci. 34
  
  Pages: 341-348
- NAID
  110007337702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Children's immunology, what can we learn from animal studies (2): Modulation of systemic Th1/Th2 immune response in infant mice after prenatal exposure to low-level toluene and toll-like receptor (TLR) 2 ligand2009
- Author(s)
  Yamamoto, S., Win-Shwe, T.T., Yoshida, Y., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  J. Toxicol. Sci. 34
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] The expression of nerve growth factor in mice lung following low-level toluene exposure2009
- Author(s)
  Fujimaki, H., Win-Shwe, T.T., Yamamoto, S., Nakajima, D., Goto, S.
- Journal Title
  
  Toxicol. Lett. 191
  
  Pages: 240-245
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Suppression of Th1-and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan2009
- Author(s)
  Yamamoto, S., Win-Shwe, T.T., Yoshida, Y., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  Inhal. Toxicol. 21(9)
  
  Pages: 793-802
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Role of CD4(+) T cells in the modulation of neurotrophin production in mice exposed to low-level toluene2008
- Author(s)
  Fujimaki, H., Win Shwe, T. T., Yamamoto, S., Nakajima, D., Goto, S.
- Journal Title
  
  Immunopharmacol. Immunotoxicol. 31
  
  Pages: 146-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Role of CD4 (+) T cells in the modulation of neurotrophin production in mice exposed to low-level toluene2008
- Author(s)
  Fujimaki, H., Win-Shwe, T.T., Yamamoto, S., Nakajima, D., Goto, S.
- Journal Title
  
  Immunopharmacol. Immunotoxicol. 31(1)
  
  Pages: 146-149
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Strain Differences in Extracellular Amino Acid Neurotransmitter Levels in the Hippocampus of Major Histocompatibility Complex Congenic Mice in Response to Toluene Exposure2008
- Author(s)
  Win-Shwe, T.T., Mitsushima, D., Yamamoto, S., Funabashi, T., Fujimaki, H.
- Journal Title
  
  Neuroimmunomodulation 16(3)
  
  Pages: 185-190
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] 時間的感受性要因に注目した化学物質の健康影響評価-マウス胎児期・授乳期における免疫・感染指標の検討-2008
- Author(s)
  山元昭二
- Journal Title
  
  国立環境研究所特別研究報告書「環境リスク研究プログラム(中間報告)
  
  Pages: 18-19
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Establishment of a Mouse Model to Asses Brain Neurotransmitter Level and Leaning Performance Simultaneously Following Toxic Chemical Exposure: Using in vivo Microdialysis and Schedule-Controlled Operant Behavior2008
- Author(s)
  Win-Shwe, T.T., Hojo, R., Mitsushima, D., Nakajima, D., Yamamoto, S., Fujimaki, H.
- Journal Title
  
  J. UOEH. 31(1)
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Modulation of neurological related allergic reaction in mice exposed to low-level toluene2007
- Author(s)
  Win Shwe, T.T., Yamamoto, S., Nakajima, D., Furuyama, A., Fukushima, A., Ahmed, S., Goto, S., Fujimaki, H.
- Journal Title
  
  Toxicol. Appl. Pharmacol. 222
  
  Pages: 17-24
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Athymic nude mice are insensitive to low-level toluene-induced up-regulation of memory-related gene expressions in the hippocampus2007
- Author(s)
  Win-Shwe, T.T., Tsukahara, S., Ahmed, S., Fukushima, A., Yamamoto, S., Kakeyama, M., Nakajima, D., Goto, S., Kobayashi, T., Fujimaki, H.
- Journal Title
  
  Neurotoxicology 28
  
  Pages: 957-964
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Toluene induces rapid and reverse of hippocampal glutamate and taurine neurotransmitter levels in mice2007
- Author(s)
  Win-Shwe, T.T., Mitsushima, D., Nakajima, D., Ahmed, S., Yamamoto, S., Tsukahara, S., Kakeyama, M., Goto, S., Fujimaki, H.
- Journal Title
  
  Toxicol. Lett. 168
  
  Pages: 76-82
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Effect of long-term exposure to low-level toluene on airway inflammatory response in mice2007
- Author(s)
  Fujimaki, H., Yamamoto, S., Win-Shwe, T.T., Hojo, R., Sato, F., Kunugita, N., Arashidani, K.
- Journal Title
  
  Toxicol. Lett. 168
  
  Pages: 132-139
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Increased hippocampal mRNA expression of neuronal synaptic plasticity related genes in mice chronically exposed to toluene at a low-level human occupational-exposure2007
- Author(s)
  Ahmed, S., Win-Shwe, T.T., Yamamoto, S., Tsukahara, S., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  Neurotoxicology 28
  
  Pages: 168-174
- Data Source
  KAKENHI-PROJECT-19590612
[Journal Article] Effects of low-level formaldehyde exposure on synaptic plasticity related gene expression in the hippocampus of immunized mice2007
- Author(s)
  Ahmed, S., Tsukahara, S., Win-Shwe, T.T., Yamamoto, S., Kunugita, N., Arashidani, K., Fujimaki, H.
- Journal Title
  
  J. Neuroimmunol. 186
  
  Pages: 104-111
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] Effects of toluene exposure on developmental immunotoxicity in infant mice brain2009
- Author(s)
  Tin-Tin-Win-Shwe, Kunugita, N., Yamamoto, S., Arashidani, K., Fujimaki, H.
- Organizer
  16th Annu. Meet. Jpn. Soc. Immunotoxicol.
- Place of Presentation
  Asahikawa
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] マウス胎仔期・新生仔期・乳仔期における低濃度トルエン曝露が免疫系の発達に及ぼす影響2009
- Author(s)
  山元昭二, Tin-Tin-Win-Shwe, 欅田尚樹, 吉田安宏, 嵐谷奎一, 藤巻秀和
- Organizer
  第16回日本免疫毒性学会学術大会
- Place of Presentation
  旭川市民文化会館(北海道)
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] Effect of perinatal toluene exposure at different developmental phases on memory function-related gene expressions in mouse brain2009
- Author(s)
  Tin-Tin-Win-Shwe, Kunugita, N., Yamamoto, S., Arashidani, K., Fujimaki, H.
- Organizer
  50th Annu. Meet. Jpn. Soc. Atomos. Environ.
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] アスベスト肺に対する常在細菌による急性曝露の影響2009
- Author(s)
  日吉孝子・山元昭二・井上健一郎・市瀬孝道
- Organizer
  第16回日本免疫毒性学会学術大会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] マウス胎仔期・新生仔期・乳仔期における低濃度トルエン曝露が免疫系の発達に及ぼす影響2009
- Author(s)
  山元昭二・Tin-Tin-Win-Shwe・欅田尚樹・吉田安宏・嵐谷奎一・藤巻秀和
- Organizer
  第16回日本免疫毒性学会学術大会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] マウス系統差で探るトルエン曝露に対する免疫系感受性要因2009
- Author(s)
  欅田尚樹・Tin-Tin-Win-Shwe・山元昭二・吉田安宏・嵐谷奎一・藤巻秀和
- Organizer
  第50回大気環境学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] VOCと免疫毒性2009
- Author(s)
  欅田尚樹・吉田安宏・嵐谷奎一・Tin-Tin-Win-Shwe・山元昭二・藤巻秀和
- Organizer
  第24回全国環境研究所交流シンポジウム「揮発性有機化合物(VOC)の動態と健康影響」
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] Strain differences influence synaptic plasticity-related gene expression in olfactory bulb of a mouse model of allergy following toluene exposure2009
- Author(s)
  Fujimaki, H., Win-Shwe T.T., Kunugita, N., Yamamoto, S., Arashidani, K.
- Organizer
  13th Congr. Eur. Fed. Neurol. Soc.
- Place of Presentation
  Florence
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] トルエンの発達期影響-感染免疫-2009
- Author(s)
  山元昭二
- Organizer
  第24回全国環境研究所交流シンポジウム「揮発性有機化合物(VOC)の動態と健康影響」
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] A potential role of hippocampal memory function-related gene expression in developmental neurotoxicity of toluene2009
- Author(s)
  Win-Shwe, T.T., Kunugita, N., Yamamoto, S., Arashidani, K., Fujimaki, H.
- Organizer
  13th Congr. Eur. Fed. Neurol. Soc.
- Place of Presentation
  Florence
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] トルエン曝露によるMHC-congenicマウス海馬における神経伝達物質レベルの変化2008
- Author(s)
  Tin-Tin-Win-Shwe・美津島大・山元昭二・藤巻秀和
- Organizer
  第15回日本免疫毒性学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] Modulation of T cell development by biological and chemical agents neonatal mice2008
- Author(s)
  Fujimaki, H., Win-Shwe, T.T., Yamamoto. S.
- Organizer
  7th Annu. Eur. Life Sci. Org. Meet.
- Place of Presentation
  Nice
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] アモサイトとクロシドライトのマウス肺への影響2008
- Author(s)
  日吉孝子、市瀬孝道、吉田成一、山元昭二、高須賀信夫、堀優作、若林敬二
- Organizer
  第49回大気環境学会
- Place of Presentation
  金沢
- Year and Date
  2008-09-17
- Data Source
  KAKENHI-PROJECT-19590592
[Presentation] 低濃度トルエン曝露が発達期のマウス免疫系に及ぼす影響2008
- Author(s)
  山元昭二・藤巻秀和
- Organizer
  第35回日本トキシコロジー学会学術年会-こどもシンポジウム5-
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] マウス乳児期におけるトルエン曝露とBCG刺激がTh1/Th2バランスの発達に及ぼす影響2008
- Author(s)
  山元昭二・Tin-Tin Win-Shwe・藤巻秀和
- Organizer
  第15回日本免疫毒性学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] トルエン曝露によるマウス海馬における記憶関連遺伝子発現増強へのT細胞の役割2007
- Author(s)
  Tin-Tin-Win-Shwe・山元昭二・藤巻秀和
- Organizer
  第14回日本免疫毒性学会学術大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590612
[Presentation] マウス胎生期および新生児期における低濃度トルエン曝露とペプチドグリカン刺激が全身性のTh1/Th2免疫バランスに及ぼす影響2007
- Author(s)
  山元昭二・福島篤・Tin-Tin-Win-Shwe・北條理恵子・藤巻秀和
- Organizer
  第14回日本免疫毒性学会学術大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590612

1. HIYOSHI Kyoko (90405580)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. ICHINOSE Takamichi (50124334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. FUJIMAKI Hidekazu (00124355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 32 results
4. FUKUSHIMA Atsushi (10442716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 吉田安宏 (10309958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉田成一 (40360060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKASUKA Nobuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

YAMAMOTO Shoji 山元 昭二

Research Projects

Research Products

Co-Researchers

黄砂感染症の健康影響評価を目指した実験的パイロットスタディ

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the acute inflammatory effect of indigenous bacterium on lung asbestosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of exposure to chemical substance with bacterial toxin on the development of Th1/Th2 balance in infant mice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Up-regulation of neurotrophin-related gene expression in mouse hippocampus following low-level toluene exposure2010

Author(s)

Journal Title

Data Source

[Journal Article] 揮発性有機化合物の胎仔期曝露による仔マウスのTh1, Th2型免疫応答のかく乱2010

Author(s)

Journal Title

Data Source

[Journal Article] 揮発性有機化合物の胎仔期曝露による仔マウスのTh1, Th2型免疫応答のかく乱2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of Th1- and Th2- type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan2009

Author(s)

Journal Title

Data Source

[Journal Article] Modulation of systemic Th1/Th2 immune response in infant mice after prenatal exposure to low-level toluene and toll-like receptor(TLR)2 ligand2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Children's immunology, what can we learn from animal studies (2): Modulation of systemic Th1/Th2 immune response in infant mice after prenatal exposure to low-level toluene and toll-like receptor (TLR) 2 ligand2009

Author(s)

Journal Title

Data Source

[Journal Article] The expression of nerve growth factor in mice lung following low-level toluene exposure2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of Th1-and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan2009

Author(s)

Journal Title

Data Source

[Journal Article] Role of CD4(+) T cells in the modulation of neurotrophin production in mice exposed to low-level toluene2008

Author(s)

Journal Title

Data Source

[Journal Article] Role of CD4 (+) T cells in the modulation of neurotrophin production in mice exposed to low-level toluene2008

Author(s)

Journal Title

Data Source

[Journal Article] Strain Differences in Extracellular Amino Acid Neurotransmitter Levels in the Hippocampus of Major Histocompatibility Complex Congenic Mice in Response to Toluene Exposure2008

Author(s)

Journal Title

Data Source

[Journal Article] 時間的感受性要因に注目した化学物質の健康影響評価-マウス胎児期・授乳期における免疫・感染指標の検討-2008

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of a Mouse Model to Asses Brain Neurotransmitter Level and Leaning Performance Simultaneously Following Toxic Chemical Exposure: Using in vivo Microdialysis and Schedule-Controlled Operant Behavior2008

Author(s)

Journal Title

Data Source

[Journal Article] Modulation of neurological related allergic reaction in mice exposed to low-level toluene2007

Author(s)

Journal Title

Data Source

[Journal Article] Athymic nude mice are insensitive to low-level toluene-induced up-regulation of memory-related gene expressions in the hippocampus2007

YAMAMOTO Shoji 山元昭二