Hashimoto Jun 橋本淳

… Alternative Names

橋本淳ハシモトジュン

HASHIMOTO JYUN 橋本淳

HASHIMOTO Jun 橋本淳

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Researcher Number	40237938
External Links
Affiliation (Current)	2025: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), その他部局等, 院外研究員
Affiliation (based on the past Project Information) *help	2017 – 2021: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), その他部局等, 部長 2007 – 2010: Osaka University, 医学系研究科, 准教授 2008 – 2009: 大阪大学, 大学院・医学系研究科, 准教授 2006: Osaka University, Graduate School of Medicine, Associate professor, 医学系研究科, 助教授 2006: 大阪大学, 医学部研究科, 助教授 … More 2006: 大阪大学, 大学院医学系研究科, 助教授 2004 – 2005: 大阪大学, 医学系研究科, 講師 2001 – 2002: 大阪大学, 医学系研究科, 講師 1997: 阪大, 医学部, 助手 1992 – 1996: 大阪大学, 医学部, 助手 1992: 大阪大学, 医学部整形外科, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery / Collagenous pathology/Allergology / Nanomaterials/Nanobioscience
Keywords	Principal Investigator E2F / 転写因子 / gene therapy / HVJ-envelope / decoy / transcription factor / proliferation of synoviocyte / immobilization / joint contracture / HVJ-evelopeベクター … More / 遺伝子治療 / HVJ-envelopeベクター / デコイ遺伝子 / 滑膜増殖 / 関節不動化 / 関節拘縮 / 生存 / M-CSF / 酸化ストレス / 高酸素濃度 / 破骨細胞 / Nkx3.2 / 低酸素 / 軟骨分化 / 骨形成 / 低酸素濃度 / 骨・軟骨代謝学 / 血中濃度 / 骨強度評価 / ELISA / 健康寿命 / 動脈硬化 / 血漿中濃度 / 椎体骨折 / 酸素分圧 / 骨強度 / 骨質 / 骨細胞 / MEPE / 新規遺伝子 / 骨形態計測 / サブトラクションハイブリダイゼイション / マーカー / 骨粗鬆症 / mRNA … More Except Principal Investigator 関節リウマチ / 骨形成因子 / 慢性関節リウマチ / サイトカイン / NFκB / 変形性関節症 / gene expression / bone morphogenetic protein / 免疫組織化学 / BMP-4 / 再生医療 / 関節リウマチ（RA） / 関節リウマチ（RA) / IL-17産生CD8+T 細胞 / １．乾癬性関節炎（PsA） / IL-17 産生CD8+T 細胞 / リンパ球 / 乾癬性関節炎（PsA） / リンパ球サブセット / 乾癬性関節炎 / Adhesive capacity / Tissue engineering / Three Dimensional / Scaffold-free / Cell Transplantation / Cartilage Repair / Regenerative Medicine / 滑膜細胞 / 接着能 / 組織工学 / 3次元化 / scaffold free / 細胞移植 / 軟骨再生 / TRAP-positive cell / osteochondral destruction / bone marrow / nurse cell / rheumatoid arthritis / 骨・軟骨破壊 / TRAP陽性細胞 / 骨軟骨破壊 / 骨髄 / ナース細胞 / Inflammation / Cytokine / Decoy / Gene therapy / Osteoarthritis / Rheumatoid Arthritis / TNFα / IL-1 / 転写因子 / 核酸医薬 / 遺伝子治療 / chondrogenesis / osteogenesis / parathyroid hormone related protein / hedgehog protein / fracture / spondylosis / 脊椎症 / 内軟骨性骨化 / 軟骨細胞 / 軟骨形成 / 骨形成 / 副甲状腺ホルモン関連蛋白 / ヘッジホッグ蛋白 / 遺伝子発現 / 骨折 / 変形性脊椎症 / bone formation / proteins / genes / osteoblast / 遺伝子 / 骨基質タンパク / 骨芽細胞 / bone repair / biomaterial / bone graft / collagen / osteosarcoma / 骨移殖 / 生体材料 / 骨移植 / 骨欠損 / 骨肉腫 / Immunohistochemistry / Northern blot analysis / Western blot analysis / Monoclonal antibody / 免 / 骨形成因子(BMP) / 単クローン抗体 / スキャフオールド / ハイドロキシアパタイト / メカニカルストレス / スキャフォールド / 骨分化 / 軟骨分化 / 幹細胞 / 硬組織 / 骨量 / 骨疾患 / 材料工学的アプローチ / X線回折 / 大理石骨病 / 生体環境 / 骨系細胞 / 骨粗鬆症 / 疾患骨 / 骨再生 / opマウス / op / 骨診断 / 透過型光学系 / 骨再生デザイン / 微小領域X線回折法 / 外場印加 / 骨再生モデル / 骨配向性 / 足場材料 / 外場 / 骨質 / 結晶配向 / アパタイト / 骨再生・骨疾患 Less

Analysis of lymphocyte subsets in psoriatic arthritis
- Principal Investigator
  
  Murakami Miho
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Tokyo Medical University
Implication of Oxygen Tension in Bone MetabolismPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Jun, 南平昭豪
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
The development of noninvasive and economical method to evaluate the bone quality using the measurement of serum levels of osteocyte-specific-proteinsPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Jun
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Osteochondral regeneration using a scaffold-free tissue engineered construct (TEC) derived from mesenchymal stem cells
- Principal Investigator
  
  NAKAMURA Norimasa
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Development of new bone method for evaluating pathological or regenerated hard tissues and bone design for biomedical application
- Principal Investigator
  
  UMAKOSHI Yukichi
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Osaka University
Development of a novel technology using mesenchymal stem cells from synovium for bone and cartilage regeneration.
- Principal Investigator
  
  NAKAMURAA Norimasa
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Analysis of molecular mechanism underlying the orthopedic diseases and the development of a novel molecular-biology-based treatment.
- Principal Investigator
  
  NAKASE Takanobu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Gene Therapy against the Progressive Joint Destruction of Rheumatoid Arthritis and Osteoarthritis
- Principal Investigator
  
  SUGAMOTO Kazuomi, 冨田哲也
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Involvement of bone marrow interstitial fibroblastic cells which support the differentiation of CD(+) peripheral-blood monocytes into TRAP positive cells. In bone and cartilage destruction in rheumatoid arthritis.
- Principal Investigator
  
  OCHI Takahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Prevention of joint contracture following joint immobilization using gene therapy's methodPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Jun
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
新規な骨粗鬆症マーカーの開発Principal Investigator
- Principal Investigator
  
  橋本淳
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Identification of novel protein molecules produced by osteoblasts
- Principal Investigator
  
  TAKAOKA Kunio
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Quatification of BMP-4 in human serum
- Principal Investigator
  
  MASUHARA Kensaku
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
Repair of massive bone defect by bone morphogenetic protein
- Principal Investigator
  
  YOSHIKAWA Hideki
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University

All 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Humanized anti-interleukin-6 receptor antibody (TOCILIZUMAB) monotherapy is more effective in slowing radiographic progression in patients with rheumatoid arthritis at high baseline risk for structural damage evaluated with levels of biomarkers, radiography and BMI : data from the SAMURAI study.2011
- Author(s)
  Hashimoto J, Garnero P, van der Heijde D, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, Yoshikawa H, Nishimoto N.
- Journal Title
  
  Mod Rheumatol. 21(1)
  
  Pages: 10-5
- NAID
  10029361106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derived from a fraction of patients with rheumatoid arthritis.2010
- Author(s)
  Igarashi H, Hashimoto J, Tomita T, Yoshikawa H, Ishihara K.
- Journal Title
  
  Clin Exp Immunol. 161(1)
  
  Pages: 71-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] Specifically modified osteopontin in rheumatoid arthritis fibroblast-like synoviocytes supports interaction with B cells and enhances production of interleukin-62009
- Author(s)
  Take Y, Nakata K, Hashimoto J, Tsuboi H, Nishimoto N, Ochi T, Yoshikawa H.
- Journal Title
  
  Arthritis Rheum 60
  
  Pages: 3591-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] High oxygen tension prolongs the suryival of osteoclast precursors via macrophage colony-stimulating factor Bone2009
- Author(s)
  Yamasaki N, Tsuboi H, Hirao M, Nampei A, Yoshikawa H, Hashimoto J
- Journal Title
  
  Bone 44
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Serum adiponectin concentrations correlate with severity ofrheumatoid arthritis evaluated by extent of joint des truetion2009
- Author(s)
  Ebina K, Fukuhara A, Ando W, Hirao M, Koga T, Oshima T, Matsuda M, Maeda K, Nakamura T, Ochi T, Shimomura I, Yoshikawa H, Hashimoto J
- Journal Title
  
  Clinical Rheumatology (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice.2009
- Author(s)
  Ebina K, Oshima K, Matsuda M, Fukuhara A, Maeda K, Kihara S, Hashimoto J, Ochi T, Banda NK, Yoshikawa H, Shimomura I.
- Journal Title
  
  Biochem Biophys Res Commun. 378
  
  Pages: 186-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] Laboratory and febrile features after joint surgery in rheumatoid arthritis patients treated with tocilizumab.2009
- Author(s)
  Hirao M, Hashimoto J, Tsuboi H, Nampei A, Nakahara H, Yoshio N, Mima T, Yoshikawa H, Nishimoto N.
- Journal Title
  
  Ann Rheum Dis. 68(5)
  
  Pages: 654-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs.2009
- Author(s)
  Hashimoto J, Garnero P, van der Heijde D, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, Yoshikawa Y, Nishimoto N
- Journal Title
  
  Mod Rheumatol 19
  
  Pages: 273-82
- NAID
  10025112961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Sperum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction.2009
- Author(s)
  Ebina K, Fukuhara A, Ando W, Hirao M, Koga T, Oshima T, Matsuda M, Maeda K, Nakamura T, Ochi T, Shimomura I, Yoshikawa H, Hashimoto J
- Journal Title
  
  Clinical Rheumatology 28
  
  Pages: 445-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Treatment of juxta-articular intraosseous cystic lesions inrheumatoid arthritis patients with interconnected porous calcium hydroxyapatite ceramic2009
- Author(s)
  Kuriyama K, Hashimoto J, Murase T, Fujii M, Nampei A, Hirao M, Tsuboi H, Myoui A, Yoshikawa H
- Journal Title
  
  Mod Rheumatol (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] High oxygen tension prolongs the survival of osteoclastprecursors via macrophage colony-stimulating factor.2009
- Author(s)
  Yamasaki N, Tsuboi H, Hirao M, Nampei A, Yoshikawa H, Hashimoto J
- Journal Title
  
  BONE 44
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] Seruadiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction.2009
- Author(s)
  Ebina K, Fukuhara A, Ando W, Hirao M, Koga T, Oshima T, Matsuda M, Maeda K, Nakamura T, Ochi T, Shimomura I, Yoshikawa H, Hashimoto J.
- Journal Title
  
  Clinical Rheumatology 28(4)
  
  Pages: 445-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] Specifically modified osteopontin in rheumatoid arthritis fibroblast-like synoviocytes supports interaction with B cells and enhances production of interleukin-6.2009
- Author(s)
  Take Y, Nakata K, Hashimoto J, Tsuboi H, Nishimoto N, Ochi T, Yoshikawa H.
- Journal Title
  
  Arthritis Rheum. 60(12)
  
  Pages: 3591-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] A case report of a patient with refractory adult-onset still's disease who was successfully treated with tocilizumab over6years.2009
- Author(s)
  Nakahara H, Mima T, Yoshio-Hoshino N, Matsushita M, Hashimoto J, Nishiimoto N
- Journal Title
  
  Mod Rheumatol (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] High oxygen tension prolongs the survival of osteoclast precursors via macrophage colony-stimulating factor Bone.2009
- Author(s)
  Yamasaki N, Tsuboi H, Hirao M, Nampei A, Yoshikawa H, Hashimoto J
- Journal Title
  
  Bone 44
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Adenovirus-mediated gene transfer of adiponectin reduces theseverity of co11agen-induced arthritis in mice.2009
- Author(s)
  Ebina K, Oshima K, Matsuda M, Fukuhara A, Maeda K, Kihara S, Hashimoto J, Ochi T, Banda NK, Yoshikawa H, Shimomura I.
- Journal Title
  
  Biochem Biophys Res Commun. 378
  
  Pages: 186-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] High oxygen tension prolongs the survival of osteoclast precursors via macrophage colony-stimulating factor Bone.2009
- Author(s)
  Yamasaki N, Tsuboi H, Hirao M, Nampei A, Yoshikawa H, Hashimoto J.
- Journal Title
  
  Bone 44(1)
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] Morphologic analysis of the medullary canal in rheumatoid elbows.2009
- Author(s)
  Goto A, Murase T, Hashimoto J, Oka K, Yoshikawa H, Sugamoto K.
- Journal Title
  
  J Shoulder Elbow Surg 18
  
  Pages: 33-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs.2009
- Author(s)
  Hashimoto J, Garnero P, van der Heijde D, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, Yoshikawa H, Nishimoto N.
- Journal Title
  
  Mod Rheumatol. 19(3)
  
  Pages: 273-82
- NAID
  10025112961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591777
[Journal Article] Characteristics of fracture and related factors in patientswith rheumatoid arthritis2008
- Author(s)
  Kampei A, Hashimoto J, Koyanagi J, Ono T, Hashimoto H, Tsumaki N, Tomita T, Sugamoto K, Nishimoto N, Ochi T, Yoshikawa H
- Journal Title
  
  Modern Rheumatology 18
  
  Pages: 180-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Alendronate treatment promotes bone formation with a less anistropic microstructure during intramembranous ossification in rats2008
- Author(s)
  M. Kashii, J. Hashimoto, T. Nakano, Y. Umakoshi and H. Yoshikawa
- Journal Title
  
  Journal of Bone and Mineral Metabolism 26
  
  Pages: 24-33
- Data Source
  KAKENHI-PROJECT-17101005
[Journal Article] Alendronate Treatment Promotes Bone Formation with a Less Anisotropic Microstructure during Intramembranous Ossificationin Rats2008
- Author(s)
  Kashii M, Hashimoto J, Nakano T, Umakoshi Y, Yoshikawa H
- Journal Title
  
  J Bone Miner Metab 26
  
  Pages: 24-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Laboratory and febrile features after joint surgery in rheumatoid arthritis patients treated with tocilizumab2008
- Author(s)
  Hirao M, Hashimoto J, Tsuboi H, Nampei A, Nakahara H, Yoshio N, Mima T, Yoshikawa H, Nishimoto N
- Journal Title
  
  Ann Rheum Dis (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] In Vitro Generation of a Scaffold-Free Tissue-Engineered Construct (TEC) Derived from Human Synovial Mesenchymal Stem Cells: Biological and Mechanical Properties, and Further Chondrogenic Potential.2008
- Author(s)
  Ando W, Tateishi K, Katakai D, Hart DA, Higuchi C, Nakata K, Hashimoto J, Fujie H, Shino K, Yoshikawa H, Nakamuara N
- Journal Title
  
  Tissue Eng Part A 14(12)
  
  Pages: 2041-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Comparison of human serum with fetal bovine serum for expansion and differentiation of human synovia1 MSC : potential feasibility for clinical app1ications.2008
- Author(s)
  Tateishi K, Ando W, Higuchi C, Hart DA, Hashimoto J, Nakata K, Yoshikawa H, Nakamura N.
- Journal Title
  
  Cell Transplant 17
  
  Pages: 549-557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Comparison of human serum with fetal bovine serum for expansion and differentiation of human synovial MSC-Potential feasibility for clinical applications.2008
- Author(s)
  Tateishi K, Ando W, Higuchi C, Hart, DA, Hashimoto J, Nakata K, Yoshikawa H, Nakamura N
- Journal Title
  
  Cell Transplant 17
  
  Pages: 549-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] Comparison of human serum with fetal bovine serum for expansion and differentiation of human synovial MSC -Potential feasibility for clinical applications.2008
- Author(s)
  Tateishi K, Ando W, Higuchi C, Hart, DA, Hashimoto J, Nakata K, Yoshikawa H, Nakamura N
- Journal Title
  
  Cell Transplant. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] In Vitro Generation of a Scaffold-Free Tissue Engineered Construct (TEC) Derived from Human Synovial Mesenchymal Stem Cells: Biological and Mechanical Properties and Further Chondrogenic Potential.2008
- Author(s)
  Ando W, Tateishi K, Katakai D, Hart DA, Nakata K, Hashimoto J, Fujie H, Shino K, Yoshikawa H, Nakamura N
- Journal Title
  
  Tissue Eng Part A 200814
  
  Pages: 2041-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with with vitamin K2 in postmenopausal women2008
- Author(s)
  Hirao M, Hashimoto J, Ando W, Ono T, Yoshikawa H
- Journal Title
  
  J Bone Miner Metab 26
  
  Pages: 260-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Alendronate Treatment Promotes Bone Formation with a Less Anisotropic Microstructure during Intramembranous Ossification in Rats2008
- Author(s)
  Kashii M, Hashimoto J, Nakano T, Umakoshi Y, Yoshikawa H
- Journal Title
  
  J Bone Miner Metab 26(1)
  
  Pages: 24-33
- NAID
  10024125772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with vitamin K2 in postmenopausal women2008
- Author(s)
  Hirao M, Hashimoto J, Ando W, Ono T, Yoshikawa H
- Journal Title
  
  J Bone Miner Metab 26(3)
  
  Pages: 260-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] In Vitro Generation of a Scaffold-Free Tissue-Engineered Construct(TEC)Derived from Human Synovia1 Mesenchyma1 stem Ce11s : Biological and Mechanical Properties, and Further Chondrogenic Potential.2008
- Author(s)
  Ando W, Tateishi K, Katakai D, Hart DA, Higuchi C, Nakata K, Hashimoto J, Fujie H, Shino K, Yoshikawa H. Nakamura N.
- Journal Title
  
  Tissue Eng Part A 14
  
  Pages: 2041-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Analysis of radiocarpal and midcarpal motion in stable and unstable rheumatoid wrists using3-D computed tomography2008
- Author(s)
  Arimitsu S, Murase T, Hashimoto J, Oka K, Sugamoto K, Yoshikawa H, Moritomo H.
- Journal Title
  
  Journal of Hand Surgery 33
  
  Pages: 189-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] In Vitro Generation of a Scaffold-Free Tissue-Engineered Construct (TEC) Derived from Human Synovial Mesenchymal stem Cells : Biological and Mechanical Properties and Further Chondrogenic Potential.2008
- Author(s)
  Ando W, Tateishi K, Katakai D, Hart DA, Higuchi c, Nakata K, Hashimoto J, Fujie H, Shino K, Yoshikawa H, Nakamura N
- Journal Title
  
  Tissue Eng Part A 14
  
  Pages: 2041-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] Radiological study of joint destruetion patterns in rheuma toid flatfoot.2008
- Author(s)
  Hattori T, Hashimoto J, Tomita T, Kitamura T, Yoshikawa H, Sugamoto K.
- Journal Title
  
  Clin Rheumatol 27
  
  Pages: 733-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes.2007
- Author(s)
  Hirao M, Hashimoto J, Yamasaki N, Ando W, Tsuboi H, Myoui A, Yoshikawa H
- Journal Title
  
  J Bone Miner Metab 25(5)
  
  Pages: 266-76
- NAID
  10024124861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390393
[Journal Article] The immunosuppressant FK506 promotes development of the chondrogenic phenotype in human synovial stromal cells via modulation of the Smad signaling pathway.2007
- Author(s)
  Tateishi K, Higuchi C, Ando W, Nakata K, Hashimoto J, Hart DA, Yoshikawa H, Nakamura N.
- Journal Title
  
  Osteoarthritis Cartilage. 15
  
  Pages: 709-718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells.2007
- Author(s)
  Ando W, Tateishi K, Hart DA, Nakata K, Hashimoto J, Fujie H, Shino K, Yoshikawa H, Nakamura N
- Journal Title
  
  Biomaterials 28
  
  Pages: 5462-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] The immunosuppressant FK506 promotes development of the chondrogenic phenotype in human synovial stromal cells via modulation of the Smad signaling pathway.2007
- Author(s)
  Tateishi K, Higuchi C, Ando W, Nakata K, Hashimoto J, Hart DA, Yoshikawa H, Nakamura N
- Journal Title
  
  Osteoarthritis Cartilage 15
  
  Pages: 709-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells.2007
- Author(s)
  Ando W, Tateishi K, Hart DA, Katakai D, Tanaka Y, Nakata K, Hashimoto J, Fujie H, Shino K, Yoshikawa H, Nakamura N.
- Journal Title
  
  Biomaterials. 28
  
  Pages: 5462-5470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390394
[Journal Article] Changes of bone quality of cortical bone formed under alendronate treatment were detected by microbeam X-ray diffraction analysis2006
- Author(s)
  M.Kashii, J.Hashimoto, T.Nakano, Y.Umakoshi, H.Yoshikawa
- Journal Title
  
  Bone 38[3]
  
  Pages: 12-13
- Data Source
  KAKENHI-PROJECT-17101005
[Journal Article] The immunosuppressant FK506 promnotes development of the chondrogenic phenotype in human synovial cells via moduration of the Smad signalling pathway.
- Author(s)
  Tateishi K, Higuchi C, Ando W, Nakata K, Hashimoto J, Hart DA, Yoshikawa H, Nakamura N
- Journal Title
  
  Osteoarthritis and Cartilage. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390438
[Journal Article] The immunosuppressant FK506 promnotes development of the chondrogenic phenotype in human synovial cells via moduration of the Smad signalling pathway.
- Author(s)
  Tateishi K, Higuchi C, Ando W, Nakata K, Hashimoto J, Hart DA, Yoshikawa H, Nakamura N
- Journal Title
  
  Osteoarthritis and Cartilage. (In press)
- Data Source
  KAKENHI-PROJECT-16390438
[Journal Article] The immunosuppressant FK506 promotes development of the chondrogenic phenotype in human synovial cells via modulation of the Smad signaling pathway.
- Author(s)
  Tateishi K, Higuchi C, Ando W, Nakata K, Hashimoto J, Hart DA, Yoshikawa H, Nakamura N.
- Journal Title
  
  Osteoarthritis and Cartilage. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390438
[Presentation] Pericellular Oxygen Concentration in Osteoblast Culture.2010
- Author(s)
  H.Oze, Hirao M, Nampei A, Shi K, Yoshikawa H, Hashimoto J.
- Organizer
  37th European Symposium on Calcified Tissues
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] Adenov irus-mediated Gene Transfer of Adiponectin Reduces Osteoclasts Differentiation and Bone Erosion of Collagen-Induced Arthritis in Mice.2010
- Author(s)
  K.Ebina, K.Oshima, Hirao M, Hashimoto J, Ochi T, Yoshikawa H, Shimomura I.
- Organizer
  37th European Symposium on Calcified Tissues
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] Pericellular oxygen concentration in osteoblast culture2010
- Author(s)
  小瀬弘樹、橋本淳, 他
- Organizer
  The European Calcified Tissue Society
- Place of Presentation
  Glasgow (UK)
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] Oxidative Stress in Rheumatoid Arthritis (RA) Patients with Tocilizumab Treatment.2009
- Author(s)
  Hirao M, Yamasaki N, Oze H, Ebina K, Nampei A, Kawato, Y, Yoshikaw H, Nishimoto N, Hashimoto J.
- Organizer
  Annual European Congress of Rheumatoligy 2009
- Year and Date
  2009-06-10
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] 関節リウマチ症例におけるヒト化抗IL-6受容体抗体(トシリズマブ)治療の酸化ストレスに与える影響2009
- Author(s)
  平尾眞、南平昭豪、蛯名耕介、山崎直美、小瀬弘樹、坪井秀規、吉川秀樹、西本憲弘、橋本淳
- Organizer
  第9回日本抗加齢医学会総会
- Place of Presentation
  東京
- Year and Date
  2009-05-28
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] NKX3.2 is an Important Mediator of Hypoxia-Induced Chodrocytic Differentiation.2009
- Author(s)
  Kawato Y, Hirao M, Hashimoto J, Tamai T, Yamasaki Y, Nampei A, Myoui A, Yoshikawa H
- Organizer
  36th European Symposium on Calcified Tissues
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] 新鮮骨折と陳旧性骨折の診断と治療の意義 : 「シンボジウム臨床と形態から椎体骨折を考える」2009
- Author(s)
  橋本淳
- Organizer
  第29回日本骨折形態計測学会
- Place of Presentation
  大阪
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] Morphological Appearance of Distal Tibia in Patients with Rheumatoid Arthritis.2009
- Author(s)
  Nampei A, Hirao M, Shi K, Sugamoto K, Yoshikawa H, Hashimoto J.
- Organizer
  Annual European Congress of Rheumatoligy 2009
- Year and Date
  2009-06-10
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] Adenovirus-mediated Gene Transfer of Adiponectin Reduces The Severity of Collagen-induced Arthritis in Mice.2009
- Author(s)
  Ebina K, Oshima K, Fukuhara A, Matsuda M, Hirao M, Nampei A, Hashimoto J, Yoshikawa H, Shimomura I
- Organizer
  Annual European Congress of Rheumatoligy 2009
- Year and Date
  2009-06-10
- Data Source
  KAKENHI-PROJECT-20591777
[Presentation] Evaluation of pinch fundion in patients with rheumatoid arthrit is2008
- Author(s)
  Akihide Nampei, Makoto Hirao, Tsuyoshi Murase, Hideki Yoshikawa, Jun Hashimoto
- Organizer
  13^<th> International Congress of the Asia Pacific League of Associations for Rheumatism
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] Nkx3.2 is an important mediator of hypoxia-induced chondrocyte differentiation2008
- Author(s)
  Kawato Y, Hirao M, Hashimoto J, Tamai N, Yamasaki N, Nampei A, Myoui A, Yoshikawa H
- Organizer
  30^<th> ASBME annual meeting
- Place of Presentation
  Montreal, Canada
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] 高酸素濃度は破骨細胞前駆細胞の持続的供給を促す2008
- Author(s)
  山崎直美, 平尾眞, 南平昭豪, 坪井秀規, 吉川秀樹, 橋本淳
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] Serum Creatine Kinase Activity is Inversely Corretated with Physical Disability, Inflamatory Activity, Rheuamatoid Factor Titer, and Prednisolone Doase in Female Patients with Rheumatoid Arthritis2008
- Author(s)
  Ebina K, Hashimoto J, Hirao M, Ando W, Nampei A, Yoshikawa H
- Organizer
  Annual European Congress of Rheumatology EULAR 2008
- Place of Presentation
  Paris, France
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] Three-Year Extension of the SAMURAI study Confirms Tocilizumab to Prevent Joint Destruction in Patients with Rheumatoif Arthritis2008
- Author(s)
  Nishimoto N, Hashimoto J, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T. Murata N, D. Van der Heijde
- Organizer
  Annual European Congress of Rheumatology EULAR 2008
- Place of Presentation
  Paris, France
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] Malleolar lengthening osteotomy for soft tissue balancing inthe correction of varus/valgus deformity during total ankle arthroplasty in patients with rheumatoid arthritis2008
- Author(s)
  Hirao M, Hashimoto J, Nampei Akihide, Hideki Tsuboi, H. C. Boots, Yoshikawa H
- Organizer
  15^<th> Congress of the Europian Rheumatism and Arthritis Surgical Society(ERASS)
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] Pinch position is the significant determinant of pinch power in patients with rheumatoid arthritis2008
- Author(s)
  Akihide Nampei, Jun Hashimoto, Makoto Hirao, Tsuyoshi Murase, Hideki Yoshikawa
- Organizer
  15^<th> Congress of the Europian Rheumatism and Arthritis Surgical Society(ERASS)
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] 酸素濃度が破骨細胞に与える影響2008
- Author(s)
  山崎直美, 平尾眞, 南平昭豪, 坪井秀規, 橋本淳, 吉川秀樹
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-19390393
[Presentation] 足場素材を用いない滑膜由来三次元人工組織(3DBT)を用いた関節内組織再生2007
- Author(s)
  立石耕介, 信貴経夫, 城山晋, 葉山悦伸, 本田博嗣, 小石逸人, 杉安謙仁郎, 野口亮介, 大森信介, 橋本佳周, 倉都滋之
- Organizer
  第73回呉整形外科研究会
- Place of Presentation
  呉,広島
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19390394
[Presentation] Histological and biomechanical assessment of cartilage repair by a scaffold-free 3D bioengineered tissue (3DBT) derived from synovial MSCs2007
- Author(s)
  Ando W, Tateishi K, Katakai D, Imura M, Take Y, Nakata K, Fujie H, Hashimoto J, Shino K, Yoshikawa H, Nakamura N
- Organizer
  International Cartilage Repair Society 2007
- Place of Presentation
  Warsaw, Poland
- Data Source
  KAKENHI-PROJECT-19390394

1. YOSHIKAWA Hideki (60191558)

# of Collaborated Projects: 10 results

# of Collaborated Products: 57 results
2. MYOUI Akira (10263261)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
3. TOMITA Tetsuya (30283766)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. NAKAMURA Norimasa (50273719)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
5. FUJIE Hiromichi (20199300)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. NAKASE Takanobu (00283755)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SUGAMOTO Kazuomi (40294061)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. ONO Keiro (70028330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. OKUBO Kousaku (40233069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TAKAOKA Kunio (30112048)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. NAKATA Ken (00283747)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
12. MTSUSAKI Michiya (00419467)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TORITSUKA Yukiyoshi (20324775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. UMAKOSHI Yukichi (00029216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. NAKANO Takayoshi (30243182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. YASUDA Hideyuki (60239762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MORIYAMA Toshiki (30283815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. AKASHI Mitsuru (20145460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SHI Kenrin (60575893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
20. HIRAO Makoto (10527708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
21. MASUHARA Kensaku (90238915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. UCHIDA Atsumasa (40176681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOSHIMURA Yasuo (10303439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SHIMIZU Tominaga (40283270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OCHI Takahiro (80112035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KANEDA Yasushi (10177537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Murakami Miho (30595591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 南平昭豪 (70464245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 谷川浩隆 (40262711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 橋本英雄 (70335363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 西本憲弘 (80273663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 辻成佳 (30795761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 乾重樹 (30324750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hashimoto Jun 橋本 淳

橋本 淳 ハシモト ジュン

HASHIMOTO JYUN 橋本 淳

HASHIMOTO Jun 橋本 淳

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Implication of Oxygen Tension in Bone MetabolismPrincipal Investigator

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The development of noninvasive and economical method to evaluate the bone quality using the measurement of serum levels of osteocyte-specific-proteinsPrincipal Investigator

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Prevention of joint contracture following joint immobilization using gene therapy's methodPrincipal Investigator

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新規な骨粗鬆症マーカーの開発Principal Investigator

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Hashimoto Jun 橋本淳

橋本淳ハシモトジュン

HASHIMOTO JYUN 橋本淳

HASHIMOTO Jun 橋本淳