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TAKAHASHI Tooru  高橋 徹

ORCIDConnect your ORCID iD *help
Researcher Number 40252952
Other IDs
Affiliation (based on the past Project Information) *help 2011 – 2022: 岡山県立大学, 保健福祉学部, 教授
2011: 岡山大学, 岡山大学病院, 准教授
2011: 岡山大学, 岡山大学病院, 助教
2010: 岡山大学, 保健福祉学部, 教授
2009 – 2010: Okayama University, 大学病院, 准教授 … More
2009: Okayama University, 岡山大学病院, 准教授
2005 – 2008: Okayama University, Hospital of Medicine and Dentistry, Lecturer, 医学部・歯学部附属病院, 講師
2007: Okayama University, Hospitals, SiniorAssistant Professor
2005: 岡山大学, 大学院医歯薬学総合研究科, 助手
2001 – 2004: Okayama University, Graduate School of Medicine and Detistry, Assistant, 大学院・医歯学総合研究科, 助手
1995 – 2000: 岡山大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Anesthesiology / Basic Section 55050:Anesthesiology-related
Except Principal Investigator
Emergency medicine / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Basic Section 55060:Emergency medicine-related / Surgical dentistry / Pathological medical chemistry
Keywords
Principal Investigator
出血性ショック / 炎症 / 出血性ショック蘇生 / アポトーシス / 急性肺傷害 / heme oxygenase-1 / ヘムオキシゲナーゼ / ストレス蛋白 / 抗炎症作用 / 酸化ストレス … More / ヘム / ヘムオキシゲナーゼ-1 / 一酸化炭素 / 周術期管理学 / ARDS / 抗炎症療法 / インフラマソーム / 蘇生後急性肺傷害 / apoptosis / oxidative stress / heme / スズ(SnCl_2) / 酸化的ストレス / 虚血性急性腎不全 / 炎症性サイトカイン / CO releasing molecule / COヘモグロビン / 吸入療法 / 好中球 / 急性肺障害 / オートファジー / Dexmedetomidine / ドラッグ‐リポジショニング / SnMP / ヘムオキシゲナーゼ―1 / ドラッグーリポジショニング / ALAS1 / Bach1 / 遊離ヘム / 塩化スズ / 横紋筋融解症 / 急性腎傷害 / 急性臓器障害 / マイトファジー / カスパーゼ / TUNEL陽性細胞 / CO-releasing molecule / 抗炎症性サイトカイン / 抗炎症薬 / CO遊離分子 / 炎症反応 / 蘇生後肺傷害 / inflammation / stress protein / hemorrhagic shock / acute lung injury / acute renal failure / 虚血-再潅流 / 急性腎不全 / 虚血再還流 / tin chloride(SnCl_2) / Heat shock protein / Ischemic acute renal failure / renal function / tin mesoporphyrin / δ-aminolevulinate synthase / heat shock protein 70 / ischemic acute renal failure / スズ / 虚血性腎不全 / 腎機能 / δ-アミノレブリン酸合成酵素 / スズメゾポルフィリン / ヘムオキシゲナーゼー1 / 8-OHdG / 一酸化炭素:CO / Heme Oxygenase-1 / 抗酸化ストレス作用 / 酸化的DNA損傷 / ビリベルジン / サイトカイン / TUNEL / activated caspase-3 / PPAR-γ / IL-10 / 抗炎症性シグナル伝達 / iNOS / TNF-α / 転写因子 / 治療効果 / 炎症性メディエーター / アミノピリン脱メチル化活性 / チトクローム P450 / 亜鉛 / 肝障害 / ハロタン … More
Except Principal Investigator
ヘムオキシゲナーゼ / ヘムオキシゲナーゼ-1 / ヘム / 酸化ストレス / 敗血症 / TNF-α / Heme / 四塩化炭素 / ストレス蛋白 / 一酸化炭素 / iNOS / Sepsis / heme oxygenase-1 / Bach1 / 集中治療学 / 炎症 / MODS / SIRS / Heme Oxygenase-1 / エンドトキシン / ヘムオキシゲナーゼ-1 / ヘムオキシゲナーゼー1 / 横紋筋融解症 / 急性腎不全 / BDNF / NF-κB / 疼痛メカニズム / 難治性疼痛 / 遺伝子治療 / Inflammation / 酸化的ストレス / 肝障害 / Heme Oxygenase / heme / ハロタン / Nrf2 / オートファジー / Heme oxygenase-1 / 出血性ショック / COヘモグロビン / 呼気一酸化炭素 / IL-11 / 急性腎傷害 / 救急医学 / 塩化スズ / ヘムオキシゲナーゼ-1 / 4-hydroxy-2-nonenal / iron / cytokine / oxidative reaction / brain / 酸化 / 4-HNE / 鉄 / サイトカイン / 酸化反応 / 脳 / Carbon, tetrachloride / Hepatic, injury / Interleukin-11 / Oxidative, stress / NF-kappaB / tumor necrosis factor-alpha / 肝臓 / tumor necrosis factor alpha / インターロイキン-11 / ウリナスタチン / 急性肺傷害 / Heme oxygenase-l / spinal cord / chronic pain / acute pain / molecular mechanisms / 脊髄 / 慢性痛 / 急性痛 / 疼痛機序 / endotoxin / interleukin-11 / anti-inflammatory cytokine / liver / sepsis / 抗炎症サイトカイン / インターロイキン11 / 抗炎症性サイトカイン / 肝 / pain mechanism / endogenous opioid peptide / intractable pain / Gene therapy / pain / 内因性オピオイドペプチド / 痛み / Oxidative stress / Intestine / Endotoxin / Carbon Monoxide / グリア細胞 / 敗血症性脳症 / 腸管 / oxidative stress / cytochrome P450-2E1 / hepatotoxicity / inhaled anesthetics / ハロタン肝障害 / 低酸素 / イソフルラン / CYP2E1遺伝子導入細胞 / CYP2E1 / 吸収麻酔薬 / CYP2E1遺伝子導入肝細胞 / HSP70 / チトクロームP450 / 吸入麻酔薬 / Transcription / Oxygen Sensing / 環境応答 / ヘム合成系 / 赤血球系 / HLA-B27 / 鉄芽球性貧血患者 / 晩発性皮膚ポルフィリン症 / 遺伝性ヘモクロマトージス / 転写調節 / 酸素応答 / heme oxygenase / stress protein / halothane / Nrf2 / Bach1 / Bach1 / Nrf2 / 急性肝傷害 / 集中治療医学 / 非特異型デルタアミノレブリン酸合成酵素(ALAS1) / ヘムオキシゲナーゼ-1(HO-1) / ヘムオキシゲナーゼ1(HO-1) / チトクロームp450 / 急性肝不全 / 貴伝子発現 / 生体肝移植 / 呼気ガス / 虚血再環流 / 再環流障害 / 肝移植 / ヘモオキシゲナーゼ / 虚血再潅流障害 / 肝臓移植 / 周術期管理 / HIF-1alpha / 自然免疫 / 消化管障害 / アポトーシス / グルタミン / 消化管傷害 / 連続呼気ガス測定 / ビリルビン / 蘇生学 / 周術期管理学 / 麻酔学 / 一回喚起量 / 血管拡張 / 肺血管抵抗 / 肺高血圧症 / 血流速度 / 血管径 / 一回換気量 / 呼気終末陽圧 / 肺微小循環 / CD14 / RFLP-PCR / LPS / Toll-like receptor / 脊髄くも膜下麻酔 / 全身麻酔 / 遺伝子多型 / TLR4 / IL-6 / 敗血症性多臓器障害 / 肺血症性脳症 Less
  • Research Projects

    (29 results)
  • Research Products

    (170 results)
  • Co-Researchers

    (35 People)
  •  Development of pharmacological therapy of ARDS by drug repositioningPrincipal Investigator

    • Principal Investigator
      TAKAHASHI TORU
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Okayama Prefectural University
  •  Protective effect of tin chloride on rhabdomyolysis-induced acute kidney injury in rats

    • Principal Investigator
      Shimizu Hiroko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  The role of mitophagy in the therapy of CO-releasing molecule against acute respiratory distress syndromePrincipal Investigator

    • Principal Investigator
      Takahashi Toru
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Okayama Prefectural University
  •  The protective role of heme oxygenase-1 and autophagy in the kidney rhabdomyolysis-associated acute kidney injury

    • Principal Investigator
      Shimizu Hiroko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Okayama University
  •  Application of biliverdin/bilirubin redox cycle to the novel therapeutic strategy against acute lung injuryPrincipal Investigator

    • Principal Investigator
      Toru Takahashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Okayama Prefectural University
  •  Nrf2 is a novel marker of oxidative stress at acute hepatic failure.

    • Principal Investigator
      HIROKO Shimizu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Okayama University
  •  Elucidation of therapeutic and anti-inflammatory effect of carbon monoxide inhalation against acute lung injuryPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Toru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama Prefectural University
  •  Bran-New Indicator of the Management for Living Donor Liver Transplantation : Exhaled Carbon Monoxide

    • Principal Investigator
      MATSUMI Masaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Bach1 mRNA expression is a novel marker of heme-mediated oxidative liver injury.

    • Principal Investigator
      SHIMIZU Hiroko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Okayama University
  •  Development of Novel Strategies for Prevention from Bacterial Translocation

    • Principal Investigator
      KATAYAMA Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Okayama University
  •  Development of CO inhalation therapy for acute lung injuryPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Toru
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  A novel biomarker of oxidative stress : Exhaled CO concentration

    • Principal Investigator
      MATSUMI Masaki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Establichment of brain oxidative model created by ferric nitrilo-triacetate(Fe-NTA)

    • Principal Investigator
      MAEDA Shigeru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Okayama University
  •  Development of cytoprotective therapy against septic multiple organ damage

    • Principal Investigator
      KATAYAMA Hiroshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Okayama University
  •  CCD生体顕微鏡を用いた肺胞と肺微小循環の動的イメージング計測とその解析

    • Principal Investigator
      竹内 護
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Development of the new strategy for acute renal failure by modulating the signal transductionPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Toru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Molecular mechanism of acute and chronic pain

    • Principal Investigator
      MIZOBUCHI Satoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Toll-like receptorの遺伝子多型が敗血症の病態と予後に及ぼす影響

    • Principal Investigator
      多賀 直行
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Okayama University
  •  An anti-inflammatory cytokine, Interleukin-11 : A therapeutic target against septic MODS

    • Principal Investigator
      KATAYAMA Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      OKAYAMA UNIVERSITY
  •  The role of glial activation on the pathogenesis of septic encephalopathy

    • Principal Investigator
      MATSUMI Masaki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Gene therapy of pain by expressing endogenous opioid peptide

    • Principal Investigator
      MIZOBUCHI Satoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Development of new therapeutic modality for acute renal failure by the inhibition of apoptosisPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Toru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  抗炎症性サイトカインとストレス蛋白が敗血症の予後に及ぼす影響

    • Principal Investigator
      KATAYAMA Hiroshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Molecular mechanism of inhaled anesthetic-induced hepatotoxicity

    • Principal Investigator
      HIRAKAWA Masahisa
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  Molecular Mechanisms Involved in Oxygen Sensing by Heme.

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Hokkaido University
  •  The role of heat shock proteins in ischemic acute renal failurePrincipal Investigator

    • Principal Investigator
      TAKAHASHI Toru
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      OKAYAMA UNIVERSITY
  •  The role of heat shock proteins in inhaled anesthetics-induced organ toxicity

    • Principal Investigator
      HIRAKAWA Masahisa
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  敗血症性脳症において一酸化炭素(CO)が果たす役割

    • Principal Investigator
      MATSUMI Masaki
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University
  •  ラットハロタン肝炎モデルに対する亜鉛の保護作用の解明Principal Investigator

    • Principal Investigator
      高橋 徹
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Okayama University

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] エンドトキシン・自然免疫研究2016

    • Author(s)
      高橋 徹
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-16K10972
  • [Book] エンドトキシン・自然免疫研究18 自然免疫における生体防御の多様性2015

    • Author(s)
      高橋 徹
    • Total Pages
      100
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-25462450
  • [Book] Heme proteins, Hemeoxygenase-1 and Oxidative stress. In "Oxidative Stress -Molecular Mechanisms and Biological Effects", edited by Volodymyr Lushchak and Halyna M. Semchyshyn2012

    • Author(s)
      Morimatsu H, Takahashi T, Shimizu H, Matsumi J, Kosaka J, Morita K
    • Publisher
      InTech -Open Access Publisher, Rijeka, Croatia
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Book] Oxidative Stress, Chapter 6 Heme proteins, Heme Oxygenase-1 and Oxidative Stress2012

    • Author(s)
      Morimatsu H, Takahashi T, Shimizu H, Matsumi J, Kosaka J, Morita K
    • Publisher
      INTECH
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Book] エンドトキシン・自然免疫研究 152012

    • Author(s)
      川西 進、高橋 徹、清水裕子、小坂順子、黒田浩佐、森松博史、森田潔
    • Total Pages
      4
    • Publisher
      医学図書出版
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Book] 低濃度一酸化炭素吸入は自然免疫系の活性を抑制してラット出血性ショック後の急性肺障害を軽減する,エンドトキシン研究142011

    • Author(s)
      川西進、高橋徹、清水裕子、小坂順子、森松博史、松三昌樹、森田潔
    • Publisher
      医学図書出版
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Book] 低濃度一酸化炭素吸入は自然免疫系の活性を抑制してフット出血性ショック後の急性肺障害を軽減するInエンドトキシン・自然免疫研究14自然免疫と生体防御2011

    • Author(s)
      川西進、高橋徹、清水裕子、小坂順子、森松博史、森田潔
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Book] エンドトキシン研究、132010

    • Author(s)
      高橋徹、井上一由、清水裕子、楳田佳奈、有森豊、川西進、松三昌樹、片山浩、森松博史、森田潔
    • Total Pages
      74
    • Publisher
      医学図書出版(株)、(東京)
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Book] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する(エンドトキシン研究、13)2010

    • Author(s)
      高橋徹、井上一由、清水裕子、楳田佳奈、有森豊、川西進、松三昌樹, 片山浩、森松博史、森田潔
    • Publisher
      医学図書出版(株)、(東京)
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Book] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する,エンドトキシン研究132010

    • Author(s)
      高橋徹、井上一由、清水裕子、楳田佳奈、有森豊、川西進、松三昌樹、片山浩、森松博史、森田潔
    • Publisher
      医学図書出版
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Book] エンドトキシン研究12 自然免疫学の新たな展開2009

    • Author(s)
      高橋徹, 松三昌樹, 片山浩, 森田潔, 他
    • Total Pages
      181
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Book] ストレス蛋白HO-1は出血性ショックによる自然免疫系の活性化を抑制し消化管を保護する(エンドトキシン研究、12)2009

    • Author(s)
      高橋徹, 井上一由, 清水裕子, 楳田佳奈, 松三昌樹, 片山浩, 森田潔
    • Publisher
      医学図書出版(株)、(東京)
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Book] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇, (分担)「エンドトキシン研究10基礎と臨床の最新知見(上西紀夫, 小川利久, 小玉正智, 横地高志, 谷徹編)2007

    • Author(s)
      高橋徹, 森松博史, 松崎孝, 清水裕子, 井上一由, 井戸佳奈, 松三昌樹, 片山浩, 森田潔
    • Publisher
      医学図書出版株式会社
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Book] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇, (分担)「エンドトキシン研究10 基礎と臨床の最新知見(上西紀夫、小川利久、小玉正智、横地高志、谷徹編)2007

    • Author(s)
      高橋徹、森松博史、松崎孝、清水裕子、井上一由、井戸佳奈、松三昌樹、片山浩、森田潔
    • Publisher
      医学図書出版株式会社、東京
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Book] 敗血症性多臓器不全におけるストレス蛋白 : ヘムオキシゲナーゼー1の発現とその意義, (分担)「エンドトキシン研究9自然免疫の最前線(熊沢義雄、小玉正智、横地高志、谷徹編)2006

    • Author(s)
      高橋徹, 上原健司, 清水裕子, 井上一由, 藤井洋泉, 松三昌樹, 片山 浩, 森田潔
    • Publisher
      医学図書出版株式会社、東京
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Protective effect of tin chloride on rhabdomyolysis-induced acute kidney injury in rats2022

    • Author(s)
      Ohtani Shinkichi、Shimizu Hiroko、Yamaoka Masakazu、Takahashi Toru、Omori Emiko、Morimatsu Hiroshi
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 3 Pages: e0265512-e0265512

    • DOI

      10.1371/journal.pone.0265512

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09381, KAKENHI-PROJECT-18K08919
  • [Journal Article] Role of the Transcription Factor BTB and CNC Homology 1 in a Rat Model of Acute Liver Injury Induced by Experimental Endotoxemia2021

    • Author(s)
      Tanioka Nohito、Shimizu Hiroko、Omori Emiko、Takahashi Toru、Yamaoka Masakazu、Morimatsu Hiroshi
    • Journal Title

      Acta Medica Okayama

      Volume: 75 Issue: 3 Pages: 363-372

    • DOI

      10.18926/AMO/62232

    • NAID

      120007089829

    • URL

      https://ousar.lib.okayama-u.ac.jp/62232

    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09381, KAKENHI-PROJECT-18K08919
  • [Journal Article] Therapeutic effect of carbon monoxide releasing molecule 3 on acute lung injury after hemorrhagic shock and resuscitation2019

    • Author(s)
      YUTA KUMADA, TORU TAKAHASHI, HIROKO SHIMIZU, RYU NAKAMURA, EMIKO OMORI, KAZUYOSHI INOUE and HIROSHI MORIMATSU
    • Journal Title

      EXPERIMENTAL AND THERAPEUTIC MEDICINE

      Volume: 17 Pages: 3429-3440

    • DOI

      10.3892/etm.2019.7390

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08919, KAKENHI-PROJECT-16K10972
  • [Journal Article] Dynamic changes in Bach1 expression in the kidney of rhabdomyolysis-associated acute kidney injury2017

    • Author(s)
      Yamaoka M, Shimizu H, Takahashi T, Omori E, Morimatsu H
    • Journal Title

      PLoS One

      Volume: 12 Issue: 7 Pages: e0180934-e0180934

    • DOI

      10.1371/journal.pone.0180934

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10972, KAKENHI-PROJECT-15K10980
  • [Journal Article] 呼気ガス:酸化ストレスの指標としての可能性2016

    • Author(s)
      高橋 徹
    • Journal Title

      ICUとCCU

      Volume: 40 Pages: 533-538

    • Data Source
      KAKENHI-PROJECT-16K10972
  • [Journal Article] Improvement of heme oxygenase-1-based heme sensor for quantifying free heme in biological samples2015

    • Author(s)
      Junichi Taira, Yukinori Nakashima, Shun Yoshihara, Shinya Koga, Shinji Sueda, Hideyuki Komatsu, Yuichiro Higashimoto, Toru Takahashi, Nohito Tanioka, Hiroko Shimizu, Hiroshi Morimatsu, Hiroshi Sakamoto
    • Journal Title

      Analytical Biochemistry

      Volume: 489 Pages: 50-52

    • DOI

      10.1016/j.ab.2015.08.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K01825, KAKENHI-PROJECT-15K10980, KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-25462450, KAKENHI-PROJECT-25870990, KAKENHI-PROJECT-15K07018
  • [Journal Article] 一酸化炭素(CO)産生酵素:ヘムオキシゲナーゼ-1が急性臓器障害において果たす役割.2015

    • Author(s)
      高橋 徹
    • Journal Title

      安定同位体と生体ガス

      Volume: 7 Pages: 42-48

    • NAID

      40020727598

    • Data Source
      KAKENHI-PROJECT-25462450
  • [Journal Article] Induction of hepatic Bach1 mRNA expression by carbone tetrachloride-induced acute liver injury in rats2014

    • Author(s)
      NOHITO TANIOKA, HIROKO SHIMIZU, TORU TAKAHASHI, EMIKO OMORI, KOSUKE KURODA, MARI SHIBATA, MASAKAZU YAMAOKA, YUICHIRO TODA, TAKASHI MATSUSAKI and HIROSHI MORIMATSU
    • Journal Title

      BIOMEDICAL REPORTS

      Volume: 2 Issue: 3 Pages: 359-363

    • DOI

      10.3892/br.2014.235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592735
  • [Journal Article] Effects of Biliverdin Administration on Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation in Rats2013

    • Author(s)
      Kosaka J, Morimatsu H, Takahashi T, Shimizu H, Kawanishi S, Omori E, Endo Y, Tamaki N, Morita M, Morita K.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 5 Pages: e63606-e63606

    • DOI

      10.1371/journal.pone.0063606

    • NAID

      120005359106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592735, KAKENHI-PROJECT-25462450
  • [Journal Article] Morita K: Inhalation of carbon monoxide following resuscitation ameliorates hemorrhagic shock-induced lung injury.2013

    • Author(s)
      Kawanishi S
    • Journal Title

      Mol Med Report

      Volume: 7 Issue: 1 Pages: 3-10

    • DOI

      10.3892/mmr.2012.1173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592258, KAKENHI-PROJECT-25462450, KAKENHI-PROJECT-25463135
  • [Journal Article] Inhalation of Carbon Monoxide after Resuscitation Ameliorates Hemorrhagic Shock-Induced Lung Injury2013

    • Author(s)
      Kawanishi, S, Takahashi T, Shimizu H, Omori E, Sato K, Matsumi M, Maeda S, Nakao A, Morimatsu H, Morita K.
    • Journal Title

      Mol Med Rep

      Volume: 7 Pages: 3-10

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Heme Proteins, Heme Oxygenase-1 and Oxidative Stress.2012

    • Author(s)
      Morimatsu, H., Takahashi, T., Shimizu, H., Matsumi, J., Kosaka, J., and Morita, K.
    • Journal Title

      InTech

      Pages: 109-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation2012

    • Author(s)
      Matsumi J, Morimatsu H, Matsusaki T, Kaku R, Shimizu H, Takahashi T, Yagi T, Matsumi M, Morita K.
    • Journal Title

      Int J Mol Med

      Volume: 29 Pages: 135-140

    • NAID

      120003751996

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] COの基礎と臨床への応用:諸刃の剣であるCOを麻酔科医は使いこなせるか?2012

    • Author(s)
      川西進、高橋徹
    • Journal Title

      LiSA

      Volume: 19 Pages: 1264-1269

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation2012

    • Author(s)
      Matsumi J, Morimatsu H, Matsusaki T, Kaku R, Shimizu H, Takahashi T, Yagi T, Matsumi M, Morita K.
    • Journal Title

      Int J Mol Med.

      Volume: vol.29 Pages: 135-140

    • NAID

      120003751996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation.2012

    • Author(s)
      Matsumi, J., Morimatsu, H., Matsusaki, T., Kaku, R., Shimizu, H., Takahashi, T., Yagi, T., Matsumi, M. and Morita, K
    • Journal Title

      Int J Mol Med

      Volume: 29 Pages: 135-40

    • NAID

      120003751996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Journal Article] Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice2012

    • Author(s)
      Tomoko Kawakami, Nitin Puri, Komal Sodhi, Lars Bellner, Toru Takahashi, Kiyoshi Morita, Rita Rezzani, Tim D. Oury, and Nader G. Abraham
    • Journal Title

      Int J Hypertens:

      Volume: 1 Pages: 1-11

    • DOI

      10.1155/2012/740203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice2012

    • Author(s)
      Kawakami T, Puri N, Sodhi K, Bellner L, Takahashi T, Morita K, Rezzani R, Tim Oury TD, and Abraham, NG.
    • Journal Title

      Int J Hypertens, Article ID 740203

      Pages: 11-11

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Induction of apoptotic change in the rat hippocampus caused by ferric nitrilotriacetate2011

    • Author(s)
      Maeda S, Takahashi T., et al
    • Journal Title

      Redox Report

      Volume: 16 Pages: 114-120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation2011

    • Author(s)
      Junya Matsumi
    • Journal Title

      International Journal of Molecur Mediceni

      Volume: 29 Pages: 135-140

    • DOI

      10.3892/ijmm.2011.821

    • NAID

      120003751996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592010, KAKENHI-PROJECT-21592307, KAKENHI-PROJECT-22591730
  • [Journal Article] 一酸化炭素2011

    • Author(s)
      高橋徹、森松博史、川西進、清水裕子、森田潔
    • Journal Title

      Journal of Medical Gases

      Volume: 13 Pages: 24-26

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Induction of apoptotic change in the rat hippocampus caused by ferric nitrilotriacetate2011

    • Author(s)
      Maeda S, Arai Y, Higuchi H, Tomoyasu Y, Mizuno R, Takahashi T, Miyawaki T.
    • Journal Title

      Redox Rep

      Volume: 16 Pages: 114-120

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] An Increase in Exhaled CO Concentration in Systemic Inflammation/Sepsis.2010

    • Author(s)
      Morimatsu H, Takahashi T, Matsusaki T, Hayashi M, Matsumi J, Shimizu H, Matsumi M, Morita K
    • Journal Title

      Journal of Breath Research 4(online publication)

      Pages: 47103-47103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Role of heme oxygenase-1 in protection of the kidney after hemorrhagic shock2010

    • Author(s)
      Arimori Y, Takahashi T, Nishie H, Inoue K, Shimizu H, Omori E, Kawanishi S, Toda Y, Morimatsu H, Morita K.
    • Journal Title

      Int J Mol Med

      Volume: 26 Pages: 27-32

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] An increase in exhaled CO concentration in systemic inflammation/sepsis.2010

    • Author(s)
      Morimatsu H, Takahashi T, Matsusaki T, Hayashi M, Matsumi J, Shimizu H, Matsumi M, Morita K.
    • Journal Title

      J Breath Res.

      Volume: 4(4) Pages: 47103-47103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Journal Article] Protective effect of carbon monoixide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2010

    • Author(s)
      Kanagawa F, Takahashi T, Inoue K, Shimizu H, Omori E, Morimatsu H, Maeda S, Katayama H, Nakao A, Morita K.
    • Journal Title

      J Trauma

      Volume: 69(1) Pages: 185-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Journal Article] Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats2010

    • Author(s)
      Kanagawa F, Takahashi T, Inoue K, Shimizu H, Omori E, Morimatsu H, Maeda S, Katayama H, Nakao A, Morita K.
    • Journal Title

      J Trauma

      Volume: 69 Pages: 185-194

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する2010

    • Author(s)
      高橋徹
    • Journal Title

      エンドトキシン研究

      Volume: 13 Pages: 65-68

    • Data Source
      KAKENHI-PROJECT-21592307
  • [Journal Article] Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2010

    • Author(s)
      Kanagawa F, Takahashi T, Shimizu H, Morita K, et al
    • Journal Title

      Journal of Trauma

      Volume: 69 Pages: 185-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] An increase in exhaled CO concentration in systemic inflammation/sepsis.2010

    • Author(s)
      Morimatsu, H., Takahashi, T., Matsusaki, T., Hayashi, M., Matsumi, J., Shimizu, H., Matsumi, M. and Morita, K.
    • Journal Title

      J Breath Res

      Volume: 4 Pages: 47103-47103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Journal Article] An Increase in Exhaled CO Concentration in Systemic Inflammation/Sepsis.2010

    • Author(s)
      Morimatsu H, Takahashi T, Shimizu H, Morita K, et al.
    • Journal Title

      Journal of Breath Research

      Volume: 4(online publication) Pages: 47103-47103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Responses to surgical stress after esophagectomy : Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor-α and inducible nitric oxide synthase.2010

    • Author(s)
      Suzuki S, Morimatsu, H, Omori E, Shimizu H, Takahashi T, Yamatsuji T, Naomoto Y, Morita K
    • Journal Title

      MolecularMedicine Reports 3

      Pages: 765-769

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Responses to surgical stress after esophagectomy: Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor-α and inducible nitric oxide synthase2010

    • Author(s)
      Suzuki S, Morimatsu, H, Omori E, Shimizu H, Takahashi T, Yamatsuji T, Naomoto Y, Morita K.
    • Journal Title

      Mol Med Rep

      Volume: 3 Pages: 765-769

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2010

    • Author(s)
      Kanagawa F, Takahashi T, Inoue K, Shimizu H, Omori E, Morimatsu H, Maeda S, Katayama H, Nakao A, Morita K
    • Journal Title

      The Journal of Trauma 69

      Pages: 185-194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Role of heme oxygenase-1 in protection of the kidney after hemorrhagic shock.2010

    • Author(s)
      Arimori Y, Takahashi T, Nishie H, Inoue K, Shimizu H, Omori E, Kawanishi S, Toda Y, Morimatsu H, Morita K
    • Journal Title

      International Journal of Molecular Medicine 26

      Pages: 27-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] An Increase in Exhaled CO Concentration in Systemic Inflammation/Sepsis2010

    • Author(s)
      Morimatsu H, Takahashi T, Matsusaki T, Hayashi M, Matsumi J, Shimizu H, Matsumi M, Morita K.
    • Journal Title

      J Breath Res

      Volume: Vol. 4: Article ID 047103 Pages: 4-4

    • Data Source
      KAKENHI-PROJECT-22591730
  • [Journal Article] Role of heme oxygenase-1 in protection of the kidney after hemorrhagic shock.2010

    • Author(s)
      Arimori Y, Takahashi T, Nishie H, Inoue K, Shimizu H, Omori E, Kawanishi S, Toda Y, Morimatsu H, Morita K.
    • Journal Title

      Int J Mol Med.

      Volume: 26(1) Pages: 27-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Journal Article] Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxysenase-1 induction2009

    • Author(s)
      Umeda K, Takahashi T, Shimizu K, Katayama H, Morita K
    • Journal Title

      Shock 31

      Pages: 40-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Increased heme catabolism in critically ill patients : correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha concentrations2009

    • Author(s)
      Morimatsu, H., Takahashi, T., Maeshima, K., Inoue, K., Kawakami, T., Shimizu, H., Takeuchi, M., Yokoyama, M., Katayama, H., Morita, K
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol Vol. 290, No. 1

      Pages: 114-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] (1th author, other 7 authors): Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock.2009

    • Author(s)
      Takahashi T, Morimatsu H, Morita K, et. al.
    • Journal Title

      J Clin Biochem Nutr Vol.44

      Pages: 28-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction2009

    • Author(s)
      Umeda K, Takahashi T, Inoue K, Shimizu H, Maeda S, Morimatsu H, Omori E, Akagi R, Katayama H, Morita K
    • Journal Title

      Shock 31

      Pages: 40-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Site-specific induction of intestinal hypoxia-inducible factor-1αafter hemorrhagic shock.2009

    • Author(s)
      Nishie H, Takahashi T, Inoue K, Shimizu H, Morimatsu H, Toda Y, Omori E, Akagi R, Katayama H, Morita K.
    • Journal Title

      Mol Med Rep 2

      Pages: 149-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Site-specific induction of intestinal hypoxia-inducible factor-lalpha after hemorrhagic shock2009

    • Author(s)
      HIROYUKI NISHIE, TORU TAKAHASHI, HIROSHI MORIMATSU, KIYOSHI MORITA, et al.
    • Journal Title

      Molecular Medicine Reports 2

      Pages: 149-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction.2009

    • Author(s)
      Umeda K, Takahashi T, Inoue K, Shimizu H, Maeda S, Morimatsu H, Omori E, Akagi R, Katayama H, Morita K.
    • Journal Title

      Shock 31

      Pages: 40-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock2009

    • Author(s)
      Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K. Heme
    • Journal Title

      J Clin Biochem Nutr 44

      Pages: 28-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] (2nd author, other 6 authors) Prevention of hemorrhagicshock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction.2009

    • Author(s)
      Umeda K, Takahashi T, Morimatsu H, Morita K, et. al.
    • Journal Title

      Shock Vol.31

      Pages: 40-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock2009

    • Author(s)
      Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K.
    • Journal Title

      J Clin Biochem Nutr 44

      Pages: 28-40

    • NAID

      130004466531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] (2nd author, other 6 authors): Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2009

    • Author(s)
      Kanagawa F, Takahashi T, Morimatsu H, Morita K, et. al.
    • Journal Title

      J Trauma (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock.2009

    • Author(s)
      Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K.
    • Journal Title

      J Clin Biochem Nutr 44

      Pages: 28-40

    • NAID

      130004466531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock2009

    • Author(s)
      Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K.
    • Journal Title

      J Clin Biochem Nutr 44

      Pages: 28-40

    • NAID

      130004466531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Journal Article] Hemin treatment abrogates monocrotaline-induced pulmonary hypertension2008

    • Author(s)
      Shimzu K, Takahashi T, Matsumi M, et al.
    • Journal Title

      Medicial Chemistry 4

      Pages: 572-576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Carbon Monoxide Ameliorates Renal Cold Ischemia-Reperfus ion Injury With an Upregulation of Vascular Endothelial Growth Factor by Activation of Hypoxia-Inducible Factor2008

    • Author(s)
      Faleo G, Nakao A, Takahashi, T, et al.
    • Journal Title

      Transplantation 85

      Pages: 1833-1840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Hemin treatment abrogates monocrotaline-induced pulmonary hypertension2008

    • Author(s)
      Shimzu K, Takahashi T, Iwasaki T, Shimizu H, Inoue K, Morimatsu H, Omori E, Matsumi M, Akagi R, Morita K
    • Journal Title

      Med Chem 4

      Pages: 572-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts.2008

    • Author(s)
      Nakao A, Takahashi, T, et al
    • Journal Title

      Kidney International 74

      Pages: 1009-1016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] 急性肺障害に対するウリナスタチンの治療効果のメカニズム2008

    • Author(s)
      高橋 徹
    • Journal Title

      侵襲と免疫 17

      Pages: 91-98

    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] 生体肝移植術中呼気一酸化炭素濃度の動態とその意義について2008

    • Author(s)
      松崎孝、森松博史、高橋徹、林真雄、佐藤哲史、佐藤健治、清水裕子、松三昌樹、森田潔
    • Journal Title

      日本Shock学会雑誌 23

      Pages: 85-89

    • NAID

      10024300637

    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] PROTECTIVE ROLE OF HEME OXYGENASE I IN THE INTESTINAL TISSUE INJURY IN HEMORRHAGIC SHOCK IN RATS2008

    • Author(s)
      Inoue K, Takahashi T, Katayama H, et al.
    • Journal Title

      SHOCK 29

      Pages: 252-261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Journal Article] Increased exhaled carbon monoxide concentration during living donor liver transplantation2008

    • Author(s)
      Matsusaki T, Morimatsu H, Takahashi T, Matsumi M, et al.
    • Journal Title

      International Journal of Molecular Medicine 21

      Pages: 75-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Increased exhaled carbon monoxide concentration during living donor liver transplantation2008

    • Author(s)
      Matsusaki T, Morimatsu H, Takahashi T, Matsumi M, Sato K, Kaku R, Sato T,Takahito Yagi, Tanaka N, Morita K
    • Journal Title

      Int J Mol Med 21

      Pages: 75-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] ラット出血性ショック後急性肺傷害に対するウリナスタチンの治療効果2007

    • Author(s)
      井上一由, 高橋 徹, 片山 浩, 他6名
    • Journal Title

      日本Shock学会雑誌 22

      Pages: 96-99

    • NAID

      10024300584

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] 酸化ストレスに対するヘムオキシゲナーゼ-1の臓器保護的役割2007

    • Author(s)
      高橋 徹、森松博史、森田 潔, 他
    • Journal Title

      日本薬理学会雑誌 130

      Pages: 252-256

    • NAID

      10020167375

    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] Heme Oxygenase-1: A Fundamental Guardian Against Oxidative Tissue Injuries in Acute Inflammation2007

    • Author(s)
      T. Takahashi, H. H. Morimatsu, et. al.
    • Journal Title

      Mini-Reviews in Medicinal Chemistry 7

      Pages: 745-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] ラット出血性ショック後急性肺傷害に対するウリナスタチンの治療効果2007

    • Author(s)
      井上一由, 高橋 徹, 井戸佳奈, 清水裕子, 森松博史, 前島亨一朗, 松三昌樹, 片山 浩,森田 潔
    • Journal Title

      日本Shock学会雑誌 22

      Pages: 96-99

    • NAID

      10024300584

    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats.2007

    • Author(s)
      Toda Y, Takahashi T, Morita K., et. al.
    • Journal Title

      International Journal of Molecular Medicine 19

      Pages: 237-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Journal Article] ラット出血性ショック後急性肺傷害に対するウリナスタチンの治療効果2007

    • Author(s)
      井上一由, 高橋 徹, 片山 浩, 他6名
    • Journal Title

      Shock学会雑誌 22

      Pages: 96-99

    • NAID

      10024300584

    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇2007

    • Author(s)
      高橋 徹、片山 浩, 他7名
    • Journal Title

      エンドトキシン研究 10

      Pages: 65-68

    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] Therapeutic effect of Urinary Trypsin Inhibitor on hemorrhagic-shock induced acute lung injury in rats2007

    • Author(s)
      Kazuyoshi, Inoue, Toru, Takahashi, Kana, Ido, Hiroko, Shimizu, Hiroshi, Morimatsu, Kyoichiro, Maeshima, Hiroshi, Katayama, Kiyoshi, Morita
    • Journal Title

      The Journal of Japan Shock Society Vol. 22, No. 2

      Pages: 96-99

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇2007

    • Author(s)
      高橋 徹、松三昌樹、他7名
    • Journal Title

      エンドトキシン研究 10

      Pages: 65-68

    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Increased heme catabolism in critically ill patients : correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha concentrations2006

    • Author(s)
      Morimatsu H, Takahashi T, Katayama H, Morita K et al. (6 persons)
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol 290・1

    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity.2006

    • Author(s)
      Kawakami T, Takahashi T, Katayama H, Morita K, Sassa S, et al.
    • Journal Title

      International Journal of Molecular Medicine 18

      Pages: 537-46

    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] Highly, liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity2006

    • Author(s)
      Kawakami, T., Takahashi, T., Shimizu, H., Nakahira, K., Takeuchi, M., Katayama, H., Yokoyama, M., Morita, K., Akagi, R., Sassa, S
    • Journal Title

      Int J Mol Med Vol. 18, No. 4

      Pages: 537-46

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] 敗血症性多臓器不全におけるストレス淡白 : ヘムオキシゲナーゼー1の発現とその意義2006

    • Author(s)
      高橋 徹, 松三昌樹, 森田 潔他
    • Journal Title

      エンドトキシン研究 9

      Pages: 70-75

    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Heme oxygenase-1 : A new drug target in oxidative tissue injuries in critically ill conditions2006

    • Author(s)
      Takahashi T, Shimizu H, Akagi R, Morita K, Sassa S.
    • Journal Title

      Drug Development Research Vol. 67

      Pages: 130-153

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Defense against oxidative tissue injury : The essential role played by heme oxygenase-12006

    • Author(s)
      Takahashi T, Morita K, Akagi R, Sassa S
    • Journal Title

      Current Enzyme Inhibition 2

      Pages: 105-124

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Defense against oxidative tissue injury : The essential role played by heme oxygenase-12006

    • Author(s)
      Takahashi T, Morito K, Akagi R, Sassa S
    • Journal Title

      Current Enzyme Inhibition 2

      Pages: 105-124

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Heme arginate pretreatment attenuates pulmonary NF-KB and AP-1 Activation induced by hemorrhagic shock via heme oxygenase-1 induction2006

    • Author(s)
      Sasaki T, Takahashi T, Maeshima K, Shimizu H, Toda Y, Morimatsu H, Takeuchi M, Yokoyama M, Akagi R, Morita K.
    • Journal Title

      Medicinal Chemistry Vol. 2

      Pages: 271-274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Heme oxygenase-1 : A New Drug Target in Oxidative Tissue Injuries in Critically III Conditions2006

    • Author(s)
      Takahashi T, Shimizu H, Akagi R, Morita K, Sassa S
    • Journal Title

      Drug Development Research 67

      Pages: 130-153

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] IIcmc Arginate Pretreatment Attenuates PuImonary NF-κB and AP-1 Activation Induced by Hemorrhagic Shock via Heme Oxygenase-1 Induction2006

    • Author(s)
      T.Sasaki, T.Takahashi, et al.
    • Journal Title

      Medicinal Chemistry 2

      Pages: 271-274

    • Data Source
      KAKENHI-PROJECT-18591705
  • [Journal Article] Heme oxygenase-1 : A New Drug Target in Oxidative Tissue In juries in Critically 111 Conditions2006

    • Author(s)
      Takahashi T, Shimizu H, Akagi R, Morita K, Sassa S
    • Journal Title

      Drug Development Research 67

      Pages: 130-153

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Increased heme catabolism in critically ill patients: correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha conce ntrations2006

    • Author(s)
      Morimatsu H, Takahashi T, Katayama H, Morita K, et. al. (6 persons)
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol 290

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity.2006

    • Author(s)
      Kawakami T, Takahashi T, Katayama H, Morita K, Sassa S, et. al.
    • Journal Title

      Int J Mol Med 18

      Pages: 537-46

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Journal Article] Defense against oxidative tissue injury : The essential role played by heme oxygenase-l2006

    • Author(s)
      Takahashi T, Morita K, Akagi R, Sassa S.
    • Journal Title

      Current Enzyme Inhibition Vol. 2

      Pages: 105-124

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Heme arginate pretreatment attenuates pulmonary NF-κB and AP-1 Activation induced by hemorrhagic shock via heme oxygenase-1 induction2006

    • Author(s)
      Sasaki T, Takahashi T, Morita K, et al.
    • Journal Title

      Medicinal Chemistry 2

      Pages: 271-274

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats2005

    • Author(s)
      Maeshima K, Takahashi T, Morita K, et al.
    • Journal Title

      Biochemical Pharmacology 69

      Pages: 1667-1680

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] ショック研究の最前線-ヘムオキシゲナーゼとショック-2005

    • Author(s)
      高橋徹, 森田 潔
    • Journal Title

      Anesthesia 21 Century 7・1-21

      Pages: 64-67

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Increased pulmonary home oxygenase-1 and delta-aminolerulinate synthase expression in monocrotaline-induced pulmonary hypertension2005

    • Author(s)
      Iwasaki T, Takahashi T, Morita K, Akagi R, Kajiya F, et al.
    • Journal Title

      Current Neurovascular Research 2・2

      Pages: 133-139

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats.2005

    • Author(s)
      Maeshima K, Takahashi T, Morita K, et al.
    • Journal Title

      Biochemical Pharmacology 69・11

      Pages: 1667-1680

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats.2005

    • Author(s)
      Maeshima K, Takahashi T, Uehara K, Shimizu H, Omori E, Yokoyama M, Tani T, Akagi R, Morita K.
    • Journal Title

      Biochemical Pharmacology Vol. 69

      Pages: 1667-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Cytoprotective effects of heme oxygenase in acute renal failure.2005

    • Author(s)
      Akagi R, Takahashi T, Sassa S.
    • Journal Title

      Contrib Nephrol 148

      Pages: 70-85

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] The lower intestinal tract-specific induction of home oxygnase-1 by glutamine protects against endotoxemic intestinal injury.2005

    • Author(s)
      Uehara K, Takahashi T, Morita K, Akagi R, Sassa, et al.
    • Journal Title

      Critical Care Medicine 33・2

      Pages: 381-390

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] Site- and cell-type- specific induction of intestinal inducible nitric oxide synthase in a rat model of endotoxemia2005

    • Author(s)
      Takahashi T, Fujii H, Morita K, et al.
    • Journal Title

      Medicinal Chemistry 1・6

      Pages: 643-647

    • Data Source
      KAKENHI-PROJECT-16591542
  • [Journal Article] The effects of pretreatment with lidocaine or bupivacaine on the spatial and temporal expression of c真Fos protein in the spinal cord caused by plantar incision in the rat.2004

    • Author(s)
      Xiaohui Sun, Masataka Yokoyama, Satoshi Mizobuchi, Rhuji Kaku, Hideki Nakatsuka, Toru Takahashi, Kiyoshi Morita
    • Journal Title

      Anesthesia & Analgesia 98

      Pages: 1093-8

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591543
  • [Journal Article] Protective role of an anti-inflammatory cytokine : Interleukin-11 on endotoxin-induced hepatic injury.2004

    • Author(s)
      Takahashi T, Maeshima K, Katayama H, et al., 7 persons
    • Journal Title

      Shock (Japan) Vol.19, No. 2

      Pages: 27-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591916
  • [Journal Article] The effects of pretreatment with lidocaine or bupivacaine on the spatial and temporal expression of c-Fos protein in the spinal cord caused by plantar incision in the rat.2004

    • Author(s)
      Xiaohui Sun, Masataka Yokoyama, Satoshi Mizobuchi, Rhuji Kaku, Hideki Nakatsuka, Toru Takahashi, Kiyoshi Morita
    • Journal Title

      Anesthesia & Analgesia 98

      Pages: 1093-1098

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591543
  • [Journal Article] Comparison of percutaneous electrical nerve stimulation with transcutaneous electrical nerve stimulation for long-term pain relief in patients with chronic low back pain.2004

    • Author(s)
      Masataka Yokoyama, Xiaohui Sun, Satoru Oku, Naoyuki Taga, Kenji Sato, Satoshi Mizobuchi, Toru Takahashi, Kiyoshi Morita
    • Journal Title

      Anesthesia & Analgesia 98

      Pages: 1552-6

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591543
  • [Journal Article] エンドトキシン投与急性肝障害モデルに対する抗炎症性サイトカイン:Interleukin-11の保護効果2004

    • Author(s)
      高橋 徹, 前島亨一郎, 他8名
    • Journal Title

      日本Shock学会雑誌 19・2

      Pages: 27-32

    • NAID

      10025680401

    • Data Source
      KAKENHI-PROJECT-15591916
  • [Journal Article] A Protective Role of Interleukin 11 on Hepatic Injury in Acute Endotoxemia2004

    • Author(s)
      Maeshima K, Takahashi T, Katayama H, et al., 7 persons
    • Journal Title

      Shock Vol.21, No.2

      Pages: 134-138

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591916
  • [Journal Article] エンドトキシン投与急性肝障害モデルに対する抗炎症性サイトカイン:Interleukin-11の保護効果2004

    • Author(s)
      高橋 徹, 前島亨一郎, 片山 浩, 他7名
    • Journal Title

      日本Shock学会雑誌 19・2

      Pages: 27-32

    • NAID

      10025680401

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591916
  • [Journal Article] The effects of pretreatment with lidocaine or bupivacaine on the spatial and temporal expression of c-Fas protein in the spinal cord caused by plantar incision in the rat2004

    • Author(s)
      Sun X, Yokoyama M, Mizobuchi S, Kaku R, Nakatsuka H, Takahashi T, Morita K.
    • Journal Title

      Anesthesia & Analgesia 98

      Pages: 1093-1098

    • Data Source
      KAKENHI-PROJECT-16591543
  • [Journal Article] A Protective Role of Interleukin 11 on Hepatic Injury in Acute Endotoxemia.2004

    • Author(s)
      Maeshima K, Takahashi T, Katayama H et al. 他7名
    • Journal Title

      Shock 21・2

      Pages: 134-138

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591916
  • [Journal Article] 敗血症性急性肝障害に対する抗炎症性サイトカインInterleukin-11の治療効果2003

    • Author(s)
      中平毅一, 高橋 徹, 片山 浩, 他8名
    • Journal Title

      エンドトキシン研究 5

      Pages: 158-163

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591916
  • [Journal Article] Protective effect of interleukin-11 on septic hepatic injury2003

    • Author(s)
      Nakahira K, Takahashi, T, Katayama H, et al., 8 persons
    • Journal Title

      Endotoxin Research Vol.6

      Pages: 158-163

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591916
  • [Presentation] Protective effect of SnCl2 on rhabdomyolysis- induced acute kidney injury in rats2020

    • Author(s)
      Shinkichi Ohtani, Hiroko Shimizu, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
    • Organizer
      International Anesthesia Research Society 2020 ANNUAL MEETING
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08919
  • [Presentation] Protectove role of Carbon monoxide (CO)/CO-releasing molecule against acute respiratory distress syndrome induced by hemorrhagic shock and resuscitation2019

    • Author(s)
      Toru Takahashi, Yuta Kumada, Hiroko Shimizu and Hiroshi Morimatsu
    • Organizer
      23th International Symposium on Molecular Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10972
  • [Presentation] Carbon Monoxide-Releasing Molecule-3 Ameliorates Lung Injury after Hemorrhagic Shock and Resuscitation2017

    • Author(s)
      Yuta Kumada, Hiroko Shimizu, Ryu Nakamura, Emiko Omori, Kazuyoshi Inoue, Toru Takahashi, Hiroshi Morimatsu
    • Organizer
      The Anesthesiology Annual Meeting 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10972
  • [Presentation] The effect of Dexmedetomidine on Lung Injury Induced by Hemorrhagic shock and Resuscitation in Rats2017

    • Author(s)
      Nakamura R, Inoue I, Kumada Y, Shimizu H, Takahashi T, Morimatsu H
    • Organizer
      Critical Care Congress
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Year and Date
      2017-01-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] Carbon Monoxide-releasing Molecule-3 Ameliorates Lung Injury after Hemorrhagic Shock and Resuscitation2017

    • Author(s)
      Yuta Kumada, Toru Takahashi, Hiroko Shimizu, Ryu Nakamura, Emiko Omori, Kazuyoshi Inoue, Hiroshi Morimatsu,
    • Organizer
      ANESTHESIOLOGY 2017 annual meeting
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] 出血性ショック蘇生時に投与したDexmedetomidineがラット蘇生後肺傷害に与える影響2017

    • Author(s)
      中村 龍, 井上 一由, 熊田 雄太, 清水 裕子, 高橋 徹, 森松 博史
    • Organizer
      第44回日本集中治療医学会学術集会
    • Place of Presentation
      札幌市教育文化会館, 札幌市, 北海道
    • Year and Date
      2017-03-09
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] Significant changes in renal Bach1 expression in rhabdomyolysis-induced aute kidney injury.2017

    • Author(s)
      Toru Takahashi, Masakazu Yamaoka, Hiroko Shimizu, Hiroshi Morimatsu
    • Organizer
      20th International Symposium on Molecular Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] Significant changes in renal Bach1 expression in rhabdomyolysis-induced aute kidney injury2017

    • Author(s)
      Toru Takahashi, Masakazu Yamaoka, Hiroko Shimizu and Hiroshi Moromatsu
    • Organizer
      20th International Symposium on Molecular Medicine
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10972
  • [Presentation] Induction of Bach1 mRNA in a rat model of acute liver injury2016

    • Author(s)
      Toru Takahashi
    • Organizer
      19th International Symposium on Molecular Medicine
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2016-10-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10972
  • [Presentation] The impact of fluid’s choice in early stage of hemorrhagic shock resuscitation on lung injury: Experimental animal study.2015

    • Author(s)
      Ryu Nakamura, Kazuyoshi Inoue, Hiroko Shimizu, Toru Takahashi, Hiroshi Morimatsu
    • Organizer
      The European Anesthesiology Congress(ESA)
    • Place of Presentation
      CityCube Berlin (ドイツ ベルリン)
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] 敗血症によるラット急性肝傷害モデルおけ転写因子 Bach1 の動態2015

    • Author(s)
      谷岡 野人 、清水 裕子 、高橋 徹 、山岡 正和 、森松 博史
    • Organizer
      日本麻酔科学会 第 62 回学術集会
    • Place of Presentation
      神戸ポートピアホテル (兵庫県神戸市)
    • Year and Date
      2015-05-29
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] Protective role of ulinastatin on lung injury and inflammation induced by hemorrhagic shock.2015

    • Author(s)
      Toru Takahashi
    • Organizer
      The 18th International Symposium on Molecular Medicine
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2015-10-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462450
  • [Presentation] THE ROLE OF TRANSCRIPTION FACTOR BACH1 IN A RAT MODEL OF ACUTE LIVER INJURY INDUCED BY EXPERIMENTAL ENDOTOXEMIA2015

    • Author(s)
      Nohito Tanioka, Hiroko Shimizu, Toru Takahashi, Emiko Omori, Masakazu Yamaoka, Ryu Nakamura, Hiroshi Morimatsu
    • Organizer
      IARS(International Anesthesia Research Society) 2015 Annual Meeting and International Science Symposium
    • Place of Presentation
      Hilton Hawaiian Village Resort・Honolulu・Hawaii, USA
    • Year and Date
      2015-03-23
    • Data Source
      KAKENHI-PROJECT-24592735
  • [Presentation] 横紋筋融解症性急性腎傷害ラットモデルにおけるBach1発現とその意義2015

    • Author(s)
      山岡 正和、清水 裕子、高橋 徹、谷岡 野人、黒田 浩佐、中村 龍、森松 博史
    • Organizer
      第42回日本集中治療医学会学術集会
    • Place of Presentation
      東京都港区台場1-9-1 ホテル日航東京
    • Year and Date
      2015-02-09
    • Data Source
      KAKENHI-PROJECT-24592735
  • [Presentation] 活性酸素の関与とその制御―抗酸化ストレス蛋白HO-1システムの臨床応用への可能性. シンポジウム:肺傷害発症と重症化のメカニズム―臨床応用への可能性―2015

    • Author(s)
      高橋 徹
    • Organizer
      日本麻酔科学会・第62回学術集会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2015-05-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25462450
  • [Presentation] DYNAMIC CHANGE IN BACH1 EXPRESSION IN A RAT MODEL OF GLYCEROL-INDUCED ACUTE KIDNEY INJURY2015

    • Author(s)
      Masakazu Yamaoka, Hiroko Shimizu, Toru Takahashi, Emiko Omori, Nohito Tanioka, Ryu Nakamura, Hiroshi Morimatsu
    • Organizer
      IARS(International Anesthesia Research Society) 2015 Annual Meeting and International Science Symposium
    • Place of Presentation
      Hilton Hawaiian Village Resort・Honolulu・Hawaii, USA
    • Year and Date
      2015-03-22
    • Data Source
      KAKENHI-PROJECT-24592735
  • [Presentation] 活性酸素の関与とその制御 ― 抗酸化ストレ蛋白 HO -1システムの臨床応用への可能性 ―2015

    • Author(s)
      高橋 徹
    • Organizer
      日本麻酔科学会 第 62 回学術集会
    • Place of Presentation
      神戸ポートピアホテル (兵庫県神戸市)
    • Year and Date
      2015-05-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] The role of transcription factor Bach1 in a rat model of acute liver injury induced by experimental endotoxemia.2015

    • Author(s)
      Nohito Tanioka, Hiroko Shimizu, Toru Takahashi, Masakazu Yamaoka, Hiroshi Morimatsu
    • Organizer
      The European Anesthesiology Congress(ESA)
    • Place of Presentation
      CityCube Berlin (ドイツ ベルリン)
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15K10980
  • [Presentation] Protective role of heme oxygenase-1/CO system in hemorrhagic shock-induced acute lung injury2013

    • Author(s)
      Toru Takahashi, Susumu Kawanishi, Jyunko Kosaka, Hiroko Shimizu, Hiroshi Morimatsu
    • Organizer
      16th International Symposium on Molecular Medicine
    • Place of Presentation
      Hotel Creta Maris Resort, Hersonissos, Crete, Greece
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592735
  • [Presentation] Protective role of heme oxygenase-1/CO system in hemorrhagic shock-induced acute lung injury2013

    • Author(s)
      Toru Takahashi, Susumu Kawanishi, Jyunko Kosaka, Hiroko Shimizu, Hiroshi Morimatsu
    • Organizer
      16th International Symposium on Molecular Medicine
    • Place of Presentation
      Hersonissos, Crete, Greece
    • Invited
    • Data Source
      KAKENHI-PROJECT-25462450
  • [Presentation] Increase in exhaled CO concentration after reperfusion of the grafted liver during living donor liver transplantation2012

    • Author(s)
      Toru Takahashi, et al.
    • Organizer
      15th International Symposium on Molecular Medicine
    • Place of Presentation
      Crete, Greece
    • Invited
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] 呼気COガスは酸化ストレスの指標か?2012

    • Author(s)
      高橋 徹
    • Organizer
      第16回日本医療ガス学会学術大会
    • Place of Presentation
      東京ステーションコンファレンス
    • Invited
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] Induction of Bach1 messenger RNA in a rat model of acute liver injury2011

    • Author(s)
      Shimizu H., Takahashi T., Omori E., Morimatsu H., Morita K.
    • Organizer
      American Society of Anesthesiologists Annual Meeting
    • Place of Presentation
      Chicago、ILLINOIS、USA
    • Year and Date
      2011-10-18
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Presentation] ビリルビン・一酸化炭素は体に良いのですか?2011

    • Author(s)
      高橋徹
    • Organizer
      埼玉麻酔科専門医会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] GLUTAMINE-INDUCED HEME OXYGENASE-1 PROTECTS AGAINST INTESTINAL TISSUE INJURY IN A RAT MODEL OF HEMORRHAGIC SHOCK2011

    • Author(s)
      Takahashi T, Morimatsu H, et al
    • Organizer
      the 11th Joint Scientific Congress of Korean-Japanese Intensivist
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] 低濃度一酸化炭素吸入は自然免疫系の活性を抑制してラット出血性ショック後の急性肺障害を軽減する2010

    • Author(s)
      川西進、高橋徹、清水裕子、小坂順子、森松博史、松三昌樹、森田潔
    • Organizer
      第16回日本エンドトキシン・自然免疫研究会
    • Place of Presentation
      かしはら万葉ホール、奈良県橿原市
    • Year and Date
      2010-11-13
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Presentation] 生体肝移植における肝Heme Oxygenase-1 mRNAと呼気一酸化炭素濃度の関係2010

    • Author(s)
      松三絢弥、清水裕子、森松博史、高橋徹、森田潔
    • Organizer
      日本麻酔学会年次総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Presentation] Protective role of heme oxygenasse-1 induction in hemorrhagic shock-induced intestinal tissue injury2010

    • Author(s)
      Toru Takahashi et al.
    • Organizer
      The 10th Joint Scientific Congress of the KSCCM and JSICM
    • Place of Presentation
      Hiroshima, Japan
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] ストレスと臓器保護~HO-1からCOまで~2010

    • Author(s)
      高橋徹
    • Organizer
      日本小児麻酔学会第16回学術集会
    • Place of Presentation
      倉敷市芸文館
    • Year and Date
      2010-09-18
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] Protective role of heme oxygenasse-1 induction in hemorrhagic shock-induced intestinal tissue injury2010

    • Author(s)
      高橋徹, 井上一由, 清水裕子, 森松博史, 片山浩, 森田潔
    • Organizer
      The 10th Joint Scientific Congress of the KSCCM and JSICM
    • Place of Presentation
      Hiroshima
    • Year and Date
      2010-03-03
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Presentation] Bachlは酸化ストレスの指標になりうるか?2009

    • Author(s)
      清水裕子、高橋徹、森田潔, 他2名
    • Organizer
      第6回 Heme oxygenase研究フォーラム
    • Place of Presentation
      京都府立医科大学青蓮会館(京都)
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Presentation] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する2009

    • Author(s)
      高橋徹、井上一由, 清水裕子, 森松博史、楳田佳奈, 片山浩, 森田潔
    • Organizer
      第15回日本エンドトキシン研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Presentation] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する2009

    • Author(s)
      高橋徹、片山浩, 森田潔, 他
    • Organizer
      日本エンドトキシン研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Presentation] Bach1は酸化ストレスの指標になりうるか?2009

    • Author(s)
      清水裕子、高橋徹、大森恵美子、森松博史、赤木玲子、森田潔
    • Organizer
      第6回Heme Oxygenase研究ファーラム
    • Place of Presentation
      京都府立医科大学青蓮会館、京都
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Presentation] 低濃度CO吸入は出血性ショック誘発急性肺障害に対して治療効果を示す2009

    • Author(s)
      金川文俊, 高橋徹, 井上一由, 清水裕子, 森松博史, 森田潔
    • Organizer
      第56回日本麻酔科学会学術集会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Presentation] Induction of Bach1 messenger RNA by heme-mediated oxidative stress2009

    • Author(s)
      Shimizu H, Takahashi T, Omori E, Akagi R, Morita K.
    • Organizer
      HEME OXYGENASES IN BIOLOGY AND MEDICINE 6th INTERNATIONAL CONGRESS ON HEME OXYGENASES
    • Place of Presentation
      Maiami、Florida、USA
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Presentation] INDUCTION OF BACH1 MESSENGER RNA BY HEME-MEDIATED OXIDATIVE STRESS2009

    • Author(s)
      Hiroko Shimizu, Toru Takahashi, Kiyoshi Morita, 他2名
    • Organizer
      HEME OXYGENASES IN BIOLOGY AND MEDICINE 6th INTERNATIONAL CONGRESS ON HEME OXYGENASES
    • Place of Presentation
      Maiami, Florida, USA
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21592307
  • [Presentation] 生体肝移植における肝Heme Oxygenase-1RNAと呼気一酸化炭素濃度の関係2009

    • Author(s)
      松三絢弥, 森松博史, 松崎孝, 高橋徹, 松三昌樹, 森田潔
    • Organizer
      第56回日本麻酔科学会
    • Place of Presentation
      神戸市
    • Year and Date
      2009-08-16
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Presentation] ラット出血性ショック後腸管障害に対するHeme Oxygenase-1(HO-1)の細胞保護効果2009

    • Author(s)
      高橋徹、清水裕子、井上一由、森松博史、片山浩、森田潔
    • Organizer
      第24回日本Shock学会総会
    • Place of Presentation
      金沢市
    • Year and Date
      2009-05-30
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Presentation] Relationship between exhaled carbon monoxide and oxidative stress in ischemic-reperfusion injury during living donor liver transplantation2009

    • Author(s)
      Matsumi J, Moritasu H, Shimizu H, Takahashi T, Morita K.
    • Organizer
      Annual meeting of the European Society of Anesthesiologists
    • Place of Presentation
      ミラノ
    • Year and Date
      2009-06-06
    • Data Source
      KAKENHI-PROJECT-21592010
  • [Presentation] PROTECTIVE ROLE OF HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM IN PULMONARY INJURY AND INFLAMMATION2008

    • Author(s)
      Toru Takahashi
    • Organizer
      The nth International Symposium on Molecular Medicine
    • Place of Presentation
      Creta Mar is Hotel, Crete, Greece
    • Year and Date
      2008-10-09
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Presentation] HO-1は出血性ショックによる自然免疫系の活性化を抑制し腸管を保護する2008

    • Author(s)
      高橋 徹, 片山 浩, 森田 潔, 他
    • Organizer
      日本エンドトキシン研究会
    • Place of Presentation
      仙台市 艮陵会館
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-20592120
  • [Presentation] PROTECTIVE ROLE OF HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM IN PULMONARY INJURY AND INFLAMMATION2008

    • Author(s)
      Toru Takahashi
    • Organizer
      The 11th International Symposium on Molecular Medicine
    • Place of Presentation
      Crete, Greece
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Presentation] HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM: A NOVEL MOLECULAR TARGET AGAINST OXIDAITVE TISSUE INJURIES2007

    • Author(s)
      Toru Takahashi
    • Organizer
      The 10th International Symposium on Molecular Medicine
    • Place of Presentation
      Crete, Greece
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Presentation] Peak Exhaled Carbon Monoxide Concentration and Hyperbilirubinemia after Liver Transplantation2007

    • Author(s)
      Matsusaki, T., Matsumi, M., Takahashi, T., et. al.
    • Organizer
      Annual Meeting of American Society of Anesthesiologists
    • Place of Presentation
      San francisco, USA
    • Year and Date
      2007-10-13
    • Data Source
      KAKENHI-PROJECT-18591705
  • [Presentation] IL-11 protects carbon tetrachloride-induced hepatic injury by stabilizing heme protein2007

    • Author(s)
      Takahashi, T., Kawakami, T., Shimizu, H., Inoue, K., Morimatsu, H., Katayama, H., Matsumi, M., Morita, K
    • Organizer
      The 22th Annual Meeting of Japan Shock Society
    • Place of Presentation
      Shiga, Japan
    • Year and Date
      2007-05-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Presentation] IL-11はヘム蛋白安定化作用により四塩化炭素肝障害に対して保護作用を示す2007

    • Author(s)
      高橋 徹、片山 浩、他6名
    • Organizer
      日本Shock学会総会
    • Place of Presentation
      滋賀県大津市
    • Year and Date
      2007-05-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591888
  • [Presentation] Protective Role Played by HO-1 Gene Expression and CO in Critically Ill Conditions2007

    • Author(s)
      Toru Takahashi
    • Organizer
      The 5th International Congress Heme Oxygenases 2007
    • Place of Presentation
      Krakow, Poland
    • Year and Date
      2007-09-09
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Presentation] HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM: A NOVEL MOLECULAR TARGET AGAINST OXIDAITVE TISSUE INJURIES2007

    • Author(s)
      Toru Takahashi
    • Organizer
      The 10th International Symposium on Molecular Medicine
    • Place of Presentation
      Creta Maris Hotel, Crete, Greece
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591795
  • [Presentation] GLUTAMINE-INDUCED HEME OXYGENASE-1 PROTECTS AGAINST INTESTINAL TISSUE INJURY IN A RAT MODEL OFHEMORRHAGIC SHOCK

    • Author(s)
      Toru Takahashi et al
    • Organizer
      Joint Scientific Congress of Korean-Japanese Intensivist
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] 四塩化炭素投与によるラット急性肝傷害における肝Bach1遺伝子の発現

    • Author(s)
      谷岡野人, 清水裕子, 高橋徹, 山岡正和, 森松博史
    • Organizer
      第41回日本集中治療医学会学術集会
    • Place of Presentation
      国立京都国際会館 (京都府京都市左京区)
    • Data Source
      KAKENHI-PROJECT-24592735
  • [Presentation] Increase in exhaled CO concentration after reperfusion of the grafted liver during living donor liver transplantation

    • Author(s)
      Toru Takahashi, et al
    • Organizer
      15th International Symposium on Molecular Medicine
    • Place of Presentation
      Crete, Greece
    • Data Source
      KAKENHI-PROJECT-22591730
  • [Presentation] Induction of Bach1 messenger RNA in the graft liver after reperfusion during living donor liver transplantation

    • Author(s)
      Hiroko Shimizu1, Toru Takahashi, Junya Matsumi, Ph.D., Emiko Omori, Takashi Matsuzaki, Hiroshi Morimatsu, Kiyoshi Morita
    • Organizer
      American Society of Anesthesiologists Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center Washington, DC, United States
    • Data Source
      KAKENHI-PROJECT-24592735
  • 1.  MORITA Kiyoshi (40108171)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 97 results
  • 2.  SHIMIZU Hiroko (80423284)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 69 results
  • 3.  MORIMATU Hiroshi (30379797)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 46 results
  • 4.  MIZOBUCHI Satoshi (70311800)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 5.  HIRAKAWA Masahisa (70033058)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  AKAGI Reiko (50150967)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 7.  MATSUMI Masaki (70219476)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 21 results
  • 8.  KATAYAMA Hiroshi (90161067)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 32 results
  • 9.  NAKATSUKA Hideki (70263580)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 10.  OGINO Tetsuya (90252949)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  OHMORI Emiko
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 12.  YOKOYAMA Masataka (20158380)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 13.  NINOMIYA Yoshifumi (70126241)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  井上 一由 (10624413)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 15.  FUJITA Hiroyoshi (60142931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  FUJII Yoshiaki (00098146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MAEDA Shigeru (50253000)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YAMAAI Yuichiro (00158057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MIYAWAKI Takuya (00219825)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山田 輝夫 (00033225)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  多賀 直行 (20346456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  竹内 護 (60284113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  梶谷 文彦 (70029114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  岩崎 達雄 (60379766)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  高橋 恭子 (50292008)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  YAMAOKA Masakazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 27.  GASSMANN Max
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  FANDREY Joac
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  佐々 茂
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SYTKOWSKI Ar
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  坂本 寛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  末田 慎二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  東元 祐一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  平 順一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  小松 英幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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