TAKAHASHI Tooru 高橋徹

Researcher Number	40252952
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2021: 岡山県立大学, 保健福祉学部, 教授 2011: 岡山大学, 岡山大学病院, 准教授 2011: 岡山大学, 岡山大学病院, 助教 2010: 岡山大学, 保健福祉学部, 教授 2009 – 2010: Okayama University, 大学病院, 准教授 … More 2009: Okayama University, 岡山大学病院, 准教授 2005 – 2008: Okayama University, Hospital of Medicine and Dentistry, Lecturer, 医学部・歯学部附属病院, 講師 2007: Okayama University, Hospitals, SiniorAssistant Professor 2005: 岡山大学, 大学院医歯薬学総合研究科, 助手 2001 – 2004: Okayama University, Graduate School of Medicine and Detistry, Assistant, 大学院・医歯学総合研究科, 助手 1995 – 2000: 岡山大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Anesthesiology / Basic Section 55050:Anesthesiology-related Except Principal Investigator Emergency medicine / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Pathological medical chemistry / Surgical dentistry / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator 炎症 / 出血性ショック / 急性肺傷害 / アポトーシス / 出血性ショック蘇生 / 周術期管理学 / 一酸化炭素 / ヘムオキシゲナーゼ-1 / ヘム / 酸化ストレス … More / 抗炎症作用 / ストレス蛋白 / heme oxygenase-1 / 急性肺障害 / 好中球 / 吸入療法 / COヘモグロビン / CO releasing molecule / 炎症性サイトカイン / 虚血性急性腎不全 / 酸化的ストレス / スズ(SnCl_2) / ヘムオキシゲナーゼ / heme / oxidative stress / apoptosis / 蘇生後急性肺傷害 / インフラマソーム / 抗炎症療法 / ARDS / ハロタン / 肝障害 / 亜鉛 / チトクローム P450 / アミノピリン脱メチル化活性 / 炎症性メディエーター / 治療効果 / 転写因子 / TNF-α / iNOS / 抗炎症性シグナル伝達 / IL-10 / PPAR-γ / activated caspase-3 / TUNEL / サイトカイン / ビリベルジン / 酸化的DNA損傷 / 抗酸化ストレス作用 / Heme Oxygenase-1 / 一酸化炭素:CO / 8-OHdG / ヘムオキシゲナーゼー1 / スズメゾポルフィリン / δ-アミノレブリン酸合成酵素 / 腎機能 / 虚血性腎不全 / スズ / ischemic acute renal failure / heat shock protein 70 / δ-aminolevulinate synthase / tin mesoporphyrin / renal function / Ischemic acute renal failure / Heat shock protein / tin chloride(SnCl_2) / 虚血再還流 / 急性腎不全 / 虚血-再潅流 / acute renal failure / acute lung injury / hemorrhagic shock / stress protein / inflammation / 蘇生後肺傷害 / 炎症反応 / CO遊離分子 / 抗炎症薬 / 抗炎症性サイトカイン / CO-releasing molecule / TUNEL陽性細胞 / カスパーゼ / マイトファジー / 急性腎傷害 / ドラッグーリポジショニング / 遊離ヘム / 塩化スズ / ヘムオキシゲナーゼ―１ / ALAS1 / Bach1 / SnMP / ドラッグ‐リポジショニング / Dexmedetomidine / オートファジー … More Except Principal Investigator ヘムオキシゲナーゼ / ヘム / ヘムオキシゲナーゼ-1 / TNF-α / 敗血症 / 酸化ストレス / 一酸化炭素 / ストレス蛋白 / 四塩化炭素 / Heme / エンドトキシン / Heme Oxygenase-1 / SIRS / MODS / 炎症 / 集中治療学 / Bach1 / heme oxygenase-1 / Sepsis / iNOS / IL-11 / 呼気一酸化炭素 / COヘモグロビン / 出血性ショック / Heme oxygenase-1 / オートファジー / Nrf2 / ハロタン / heme / Heme Oxygenase / 肝障害 / 酸化的ストレス / Inflammation / 遺伝子治療 / 難治性疼痛 / 疼痛メカニズム / NF-κB / BDNF / 横紋筋融解症 / ヘムオキシゲナーゼー１ / 肺血症性脳症 / 敗血症性多臓器障害 / IL-6 / TLR4 / 遺伝子多型 / 全身麻酔 / 脊髄くも膜下麻酔 / Toll-like receptor / LPS / RFLP-PCR / CD14 / 肺微小循環 / 呼気終末陽圧 / 一回換気量 / 血管径 / 血流速度 / 肺高血圧症 / 肺血管抵抗 / 血管拡張 / 一回喚起量 / 麻酔学 / 周術期管理学 / 蘇生学 / ビリルビン / 連続呼気ガス測定 / 消化管傷害 / グルタミン / アポトーシス / 消化管障害 / 自然免疫 / HIF-1alpha / 周術期管理 / 肝臓移植 / 虚血再潅流障害 / ヘモオキシゲナーゼ / 肝移植 / 再環流障害 / 虚血再環流 / 呼気ガス / 生体肝移植 / 貴伝子発現 / 急性肝不全 / チトクロームp450 / ヘムオキシゲナーゼ1(HO-1) / ヘムオキシゲナーゼ-1(HO-1) / 非特異型デルタアミノレブリン酸合成酵素(ALAS1) / 集中治療医学 / 急性肝傷害 / Nｒｆ２ / Ｂａｃｈ１ / Bａｃｈ１ / Ｎｒｆ２ / halothane / stress protein / heme oxygenase / 酸素応答 / 転写調節 / 遺伝性ヘモクロマトージス / 晩発性皮膚ポルフィリン症 / 鉄芽球性貧血患者 / HLA-B27 / 赤血球系 / ヘム合成系 / 環境応答 / Oxygen Sensing / Transcription / 吸入麻酔薬 / チトクロームP450 / HSP70 / CYP2E1遺伝子導入肝細胞 / 吸収麻酔薬 / CYP2E1 / CYP2E1遺伝子導入細胞 / イソフルラン / 低酸素 / ハロタン肝障害 / inhaled anesthetics / hepatotoxicity / cytochrome P450-2E1 / oxidative stress / 腸管 / 敗血症性脳症 / グリア細胞 / Carbon Monoxide / Endotoxin / Intestine / Oxidative stress / 痛み / 内因性オピオイドペプチド / pain / Gene therapy / intractable pain / endogenous opioid peptide / pain mechanism / 肝 / 抗炎症性サイトカイン / インターロイキン11 / 抗炎症サイトカイン / sepsis / liver / anti-inflammatory cytokine / interleukin-11 / endotoxin / 疼痛機序 / 急性痛 / 慢性痛 / 脊髄 / molecular mechanisms / acute pain / chronic pain / spinal cord / Heme oxygenase-l / 急性肺傷害 / ウリナスタチン / インターロイキン-11 / tumor necrosis factor alpha / 肝臓 / tumor necrosis factor-alpha / NF-kappaB / Oxidative, stress / Interleukin-11 / Hepatic, injury / Carbon, tetrachloride / 脳 / 酸化反応 / サイトカイン / 鉄 / 4-HNE / 酸化 / brain / oxidative reaction / cytokine / iron / 4-hydroxy-2-nonenal / 急性腎不全 / ヘムオキシゲナーゼ－１ / ヘムオキシゲナーゼ-１ / 救急医学 / 急性腎傷害 / 塩化スズ Less

ドラッグ・リポジショニングを応用した急性呼吸窮迫症候群に対する薬物療法の開発Principal Investigator
- Principal Investigator
  
  高橋徹
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Okayama Prefectural University
横紋筋融解症後腎傷害に対する細胞保護蛋白ヘムオキシゲナーゼ誘導による治療法の開発
- Principal Investigator
  
  清水裕子
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Okayama University
The role of mitophagy in the therapy of CO-releasing molecule against acute respiratory distress syndromePrincipal Investigator
- Principal Investigator
  
  Takahashi Toru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Okayama Prefectural University
The protective role of heme oxygenase-1 and autophagy in the kidney rhabdomyolysis-associated acute kidney injury
- Principal Investigator
  
  Shimizu Hiroko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Okayama University
Application of biliverdin/bilirubin redox cycle to the novel therapeutic strategy against acute lung injuryPrincipal Investigator
- Principal Investigator
  
  Toru Takahashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Okayama Prefectural University
Nrf2 is a novel marker of oxidative stress at acute hepatic failure.
- Principal Investigator
  
  HIROKO Shimizu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Okayama University
Elucidation of therapeutic and anti-inflammatory effect of carbon monoxide inhalation against acute lung injuryPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama Prefectural University
Bran-New Indicator of the Management for Living Donor Liver Transplantation : Exhaled Carbon Monoxide
- Principal Investigator
  
  MATSUMI Masaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Bach1 mRNA expression is a novel marker of heme-mediated oxidative liver injury.
- Principal Investigator
  
  SHIMIZU Hiroko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Okayama University
Development of Novel Strategies for Prevention from Bacterial Translocation
- Principal Investigator
  
  KATAYAMA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Okayama University
Development of CO inhalation therapy for acute lung injuryPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Toru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
A novel biomarker of oxidative stress : Exhaled CO concentration
- Principal Investigator
  
  MATSUMI Masaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Establichment of brain oxidative model created by ferric nitrilo-triacetate(Fe-NTA)
- Principal Investigator
  
  MAEDA Shigeru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Okayama University
Development of cytoprotective therapy against septic multiple organ damage
- Principal Investigator
  
  KATAYAMA Hiroshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Okayama University
CCD生体顕微鏡を用いた肺胞と肺微小循環の動的イメージング計測とその解析
- Principal Investigator
  
  竹内護
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Development of the new strategy for acute renal failure by modulating the signal transductionPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Toru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Molecular mechanism of acute and chronic pain
- Principal Investigator
  
  MIZOBUCHI Satoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  OKAYAMA UNIVERSITY
Toll-like receptorの遺伝子多型が敗血症の病態と予後に及ぼす影響
- Principal Investigator
  
  多賀直行
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Okayama University
An anti-inflammatory cytokine, Interleukin-11 : A therapeutic target against septic MODS
- Principal Investigator
  
  KATAYAMA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  OKAYAMA UNIVERSITY
The role of glial activation on the pathogenesis of septic encephalopathy
- Principal Investigator
  
  MATSUMI Masaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Gene therapy of pain by expressing endogenous opioid peptide
- Principal Investigator
  
  MIZOBUCHI Satoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  OKAYAMA UNIVERSITY
Development of new therapeutic modality for acute renal failure by the inhibition of apoptosisPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Toru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
抗炎症性サイトカインとストレス蛋白が敗血症の予後に及ぼす影響
- Principal Investigator
  
  KATAYAMA Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Molecular mechanism of inhaled anesthetic-induced hepatotoxicity
- Principal Investigator
  
  HIRAKAWA Masahisa
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
Molecular Mechanisms Involved in Oxygen Sensing by Heme.
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
The role of heat shock proteins in ischemic acute renal failurePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Toru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  OKAYAMA UNIVERSITY
The role of heat shock proteins in inhaled anesthetics-induced organ toxicity
- Principal Investigator
  
  HIRAKAWA Masahisa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
敗血症性脳症において一酸化炭素(CO)が果たす役割
- Principal Investigator
  
  MATSUMI Masaki
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University
ラットハロタン肝炎モデルに対する亜鉛の保護作用の解明Principal Investigator
- Principal Investigator
  
  高橋徹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Okayama University

[Book] エンドトキシン・自然免疫研究2016
- Author(s)
  高橋　徹
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-16K10972
[Book] エンドトキシン・自然免疫研究18 自然免疫における生体防御の多様性2015
- Author(s)
  高橋　徹
- Total Pages
  100
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-25462450
[Book] Heme proteins, Hemeoxygenase-1 and Oxidative stress. In "Oxidative Stress -Molecular Mechanisms and Biological Effects", edited by Volodymyr Lushchak and Halyna M. Semchyshyn2012
- Author(s)
  Morimatsu H, Takahashi T, Shimizu H, Matsumi J, Kosaka J, Morita K
- Publisher
  InTech -Open Access Publisher, Rijeka, Croatia
- Data Source
  KAKENHI-PROJECT-22591730
[Book] Oxidative Stress, Chapter 6 Heme proteins, Heme Oxygenase-1 and Oxidative Stress2012
- Author(s)
  Morimatsu H, Takahashi T, Shimizu H, Matsumi J, Kosaka J, Morita K
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-21592307
[Book] エンドトキシン・自然免疫研究　１５2012
- Author(s)
  川西　進、高橋　徹、清水裕子、小坂順子、黒田浩佐、森松博史、森田潔
- Total Pages
  4
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-22591730
[Book] 低濃度一酸化炭素吸入は自然免疫系の活性を抑制してラット出血性ショック後の急性肺障害を軽減する,エンドトキシン研究142011
- Author(s)
  川西進、高橋徹、清水裕子、小坂順子、森松博史、松三昌樹、森田潔
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-21592307
[Book] 低濃度一酸化炭素吸入は自然免疫系の活性を抑制してフット出血性ショック後の急性肺障害を軽減するInエンドトキシン・自然免疫研究14自然免疫と生体防御2011
- Author(s)
  川西進、高橋徹、清水裕子、小坂順子、森松博史、森田潔
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-22591730
[Book] エンドトキシン研究、132010
- Author(s)
  高橋徹、井上一由、清水裕子、楳田佳奈、有森豊、川西進、松三昌樹、片山浩、森松博史、森田潔
- Total Pages
  74
- Publisher
  医学図書出版(株)、(東京)
- Data Source
  KAKENHI-PROJECT-20592120
[Book] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する(エンドトキシン研究、13)2010
- Author(s)
  高橋徹、井上一由、清水裕子、楳田佳奈、有森豊、川西進、松三昌樹, 片山浩、森松博史、森田潔
- Publisher
  医学図書出版(株)、(東京)
- Data Source
  KAKENHI-PROJECT-20592120
[Book] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する,エンドトキシン研究132010
- Author(s)
  高橋徹、井上一由、清水裕子、楳田佳奈、有森豊、川西進、松三昌樹、片山浩、森松博史、森田潔
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-21592307
[Book] エンドトキシン研究12 自然免疫学の新たな展開2009
- Author(s)
  高橋徹, 松三昌樹, 片山浩, 森田潔, 他
- Total Pages
  181
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-21592010
[Book] ストレス蛋白HO-1は出血性ショックによる自然免疫系の活性化を抑制し消化管を保護する(エンドトキシン研究、12)2009
- Author(s)
  高橋徹, 井上一由, 清水裕子, 楳田佳奈, 松三昌樹, 片山浩, 森田潔
- Publisher
  医学図書出版(株)、(東京)
- Data Source
  KAKENHI-PROJECT-20592120
[Book] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇, (分担)「エンドトキシン研究10基礎と臨床の最新知見(上西紀夫, 小川利久, 小玉正智, 横地高志, 谷徹編)2007
- Author(s)
  高橋徹, 森松博史, 松崎孝, 清水裕子, 井上一由, 井戸佳奈, 松三昌樹, 片山浩, 森田潔
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-19591795
[Book] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇, (分担)「エンドトキシン研究10 基礎と臨床の最新知見(上西紀夫、小川利久、小玉正智、横地高志、谷徹編)2007
- Author(s)
  高橋徹、森松博史、松崎孝、清水裕子、井上一由、井戸佳奈、松三昌樹、片山浩、森田潔
- Publisher
  医学図書出版株式会社、東京
- Data Source
  KAKENHI-PROJECT-18591705
[Book] 敗血症性多臓器不全におけるストレス蛋白 : ヘムオキシゲナーゼー1の発現とその意義, (分担)「エンドトキシン研究9自然免疫の最前線(熊沢義雄、小玉正智、横地高志、谷徹編)2006
- Author(s)
  高橋徹, 上原健司, 清水裕子, 井上一由, 藤井洋泉, 松三昌樹, 片山浩, 森田潔
- Publisher
  医学図書出版株式会社、東京
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Protective effect of tin chloride on rhabdomyolysis-induced acute kidney injury in rats2022
- Author(s)
  Ohtani Shinkichi、Shimizu Hiroko、Yamaoka Masakazu、Takahashi Toru、Omori Emiko、Morimatsu Hiroshi
- Journal Title
  
  PLoS ONE
  
  Volume: 17
- DOI
  10.1371/journal.pone.0265512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09381, KAKENHI-PROJECT-18K08919
[Journal Article] Role of the Transcription Factor BTB and CNC Homology 1 in a Rat Model of Acute Liver Injury Induced by Experimental Endotoxemia2021
- Author(s)
  Tanioka Nohito、Shimizu Hiroko、Omori Emiko、Takahashi Toru、Yamaoka Masakazu、Morimatsu Hiroshi
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 75 Issue: 3 Pages: 363-372
- DOI
  10.18926/AMO/62232
- NAID
  120007089829
- URL
  https://ousar.lib.okayama-u.ac.jp/62232
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09381, KAKENHI-PROJECT-18K08919
[Journal Article] Therapeutic Effect of Carbon Monoxide-Releasing molecule-3 on Acute Lung Injury After Hemorrhagic Shock and Resuscitation2019
- Author(s)
  YUTA KUMADA, TORU TAKAHASHI, HIROKO SHIMIZU, RYU NAKAMURA, EMIKO OMORI, KAZUYOSHI INOUE and HIROSHI MORIMATSU
- Journal Title
  
  EXPERIMENTAL AND THERAPEUTIC MEDICINE
  
  Volume: 17 Pages: 3429-3440
- DOI
  10.3892/etm.2019.7390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08919, KAKENHI-PROJECT-16K10972
[Journal Article] Dynamic changes in Bach1 expression in the kidney of rhabdomyolysis-associated acute kidney injury.2017
- Author(s)
  Yamaoka M, Shimizu H, Takahashi T, Omori E, Morimatsu H
- Journal Title
  
  PLoS One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0180934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10972, KAKENHI-PROJECT-15K10980
[Journal Article] 呼気ガス：酸化ストレスの指標としての可能性2016
- Author(s)
  高橋　徹
- Journal Title
  
  ICUとCCU
  
  Volume: 40 Pages: 533-538
- Data Source
  KAKENHI-PROJECT-16K10972
[Journal Article] IMPROVEMENT OF HEME OXYGENASE-1-BASED HEME SENSOR FOR QUANTIFYING FREE HEME IN BIOLOGICAL SAMPLES.2015
- Author(s)
  Junichi Taira, Yukinori Nakashima, Shun Yoshihara, Shinya Koga, Shinji Sueda, Hideyuki Komatsu, Yuichiro Higashimoto, Toru Takahashi, Nohito Tanioka, Hiroko Shimizu, Hiroshi Morimatsu, Hiroshi Sakamoto
- Journal Title
  
  Anal. Biochem.
  
  Volume: 489 Pages: 50-52
- DOI
  10.1016/j.ab.2015.08.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01825, KAKENHI-PROJECT-15K10980, KAKENHI-PROJECT-25440056, KAKENHI-PROJECT-25462450, KAKENHI-PROJECT-25870990, KAKENHI-PROJECT-15K07018
[Journal Article] 一酸化炭素(CO)産生酵素：ヘムオキシゲナーゼ－１が急性臓器障害において果たす役割.2015
- Author(s)
  高橋　徹
- Journal Title
  
  安定同位体と生体ガス
  
  Volume: 7 Pages: 42-48
- NAID
  40020727598
- Data Source
  KAKENHI-PROJECT-25462450
[Journal Article] Induction of hepatic Bach1 mRNA expression by carbone tetrachloride-induced acute liver injury in rats2014
- Author(s)
  NOHITO TANIOKA, HIROKO SHIMIZU, TORU TAKAHASHI, EMIKO OMORI, KOSUKE KURODA, MARI SHIBATA, MASAKAZU YAMAOKA, YUICHIRO TODA, TAKASHI MATSUSAKI and HIROSHI MORIMATSU
- Journal Title
  
  BIOMEDICAL REPORTS
  
  Volume: 2 Pages: 359-363
- DOI
  10.3892/br.2014.235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592735
[Journal Article] Effects of Biliverdin Administration on Acute Lung Injury Induced by Hemorrhagic Shock and Resuscitation in Rats2013
- Author(s)
  Kosaka J, Morimatsu H, Takahashi T, Shimizu H, Kawanishi S, Omori E, Endo Y, Tamaki N, Morita M, Morita K.
- Journal Title
  
  PLOS ONE
  
  Volume: 8
- DOI
  10.1371/journal.pone.0063606
- NAID
  120005359106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592735, KAKENHI-PROJECT-25462450
[Journal Article] Inhalation of Carbon Monoxide after Resuscitation Ameliorates Hemorrhagic Shock-Induced Lung Injury2013
- Author(s)
  Kawanishi S
- Journal Title
  
  Mol Med Rep
  
  Volume: 7 Pages: 3-10
- DOI
  10.3892/mmr.2012.1173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592258, KAKENHI-PROJECT-25462450, KAKENHI-PROJECT-25463135
[Journal Article] Inhalation of Carbon Monoxide after Resuscitation Ameliorates Hemorrhagic Shock-Induced Lung Injury2013
- Author(s)
  Kawanishi, S, Takahashi T, Shimizu H, Omori E, Sato K, Matsumi M, Maeda S, Nakao A, Morimatsu H, Morita K.
- Journal Title
  
  Mol Med Rep
  
  Volume: 7 Pages: 3-10
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Heme Proteins, Heme Oxygenase-1 and Oxidative Stress.2012
- Author(s)
  Morimatsu, H., Takahashi, T., Shimizu, H., Matsumi, J., Kosaka, J., and Morita, K.
- Journal Title
  
  InTech
  
  Pages: 109-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592010
[Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation2012
- Author(s)
  Matsumi J, Morimatsu H, Matsusaki T, Kaku R, Shimizu H, Takahashi T, Yagi T, Matsumi M, Morita K.
- Journal Title
  
  Int J Mol Med
  
  Volume: 29 Pages: 135-140
- NAID
  120003751996
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver durin living dopor liver transplantation2012
- Author(s)
  Junya Matsumi
- Journal Title
  
  Int J Mol Med
  
  Volume: 29 Pages: 135-140
- DOI
  10.3892/ijmm.2011.821
- NAID
  120003751996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592010, KAKENHI-PROJECT-21592307, KAKENHI-PROJECT-22591730
[Journal Article] COの基礎と臨床への応用：諸刃の剣であるCOを麻酔科医は使いこなせるか？2012
- Author(s)
  川西進、高橋徹
- Journal Title
  
  LiSA
  
  Volume: 19 Pages: 1264-1269
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation2012
- Author(s)
  Matsumi J, Morimatsu H, Matsusaki T, Kaku R, Shimizu H, Takahashi T, Yagi T, Matsumi M, Morita K.
- Journal Title
  
  Int J Mol Med.
  
  Volume: vol.29 Pages: 135-140
- NAID
  120003751996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592307
[Journal Article] Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation.2012
- Author(s)
  Matsumi, J., Morimatsu, H., Matsusaki, T., Kaku, R., Shimizu, H., Takahashi, T., Yagi, T., Matsumi, M. and Morita, K
- Journal Title
  
  Int J Mol Med
  
  Volume: 29 Pages: 135-40
- NAID
  120003751996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592010
[Journal Article] Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice2012
- Author(s)
  Tomoko Kawakami, Nitin Puri, Komal Sodhi, Lars Bellner, Toru Takahashi, Kiyoshi Morita, Rita Rezzani, Tim D. Oury, and Nader G. Abraham
- Journal Title
  
  Int J Hypertens:
  
  Volume: 1
- DOI
  10.1155/2012/740203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice2012
- Author(s)
  Kawakami T, Puri N, Sodhi K, Bellner L, Takahashi T, Morita K, Rezzani R, Tim Oury TD, and Abraham, NG.
- Journal Title
  
  Int J Hypertens, Article ID 740203
  
  Pages: 11-11
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Induction of apoptotic change in the rat hippocampus caused by ferric nitrilotriacetate2011
- Author(s)
  Maeda S, Takahashi T., et al
- Journal Title
  
  Redox Report
  
  Volume: 16 Pages: 114-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] 一酸化炭素2011
- Author(s)
  高橋徹、森松博史、川西進、清水裕子、森田潔
- Journal Title
  
  Journal of Medical Gases
  
  Volume: 13 Pages: 24-26
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Induction of apoptotic change in the rat hippocampus caused by ferric nitrilotriacetate2011
- Author(s)
  Maeda S, Arai Y, Higuchi H, Tomoyasu Y, Mizuno R, Takahashi T, Miyawaki T.
- Journal Title
  
  Redox Rep
  
  Volume: 16 Pages: 114-120
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] An Increase in Exhaled CO Concentration in Systemic Inflammation/Sepsis.2010
- Author(s)
  Morimatsu H, Takahashi T, Matsusaki T, Hayashi M, Matsumi J, Shimizu H, Matsumi M, Morita K
- Journal Title
  
  Journal of Breath Research 4(online publication)
  
  Pages: 47103-47103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Role of heme oxygenase-1 in protection of the kidney after hemorrhagic shock2010
- Author(s)
  Arimori Y, Takahashi T, Nishie H, Inoue K, Shimizu H, Omori E, Kawanishi S, Toda Y, Morimatsu H, Morita K.
- Journal Title
  
  Int J Mol Med
  
  Volume: 26 Pages: 27-32
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] An increase in exhaled CO concentration in systemic inflammation/sepsis.2010
- Author(s)
  Morimatsu H, Takahashi T, Matsusaki T, Hayashi M, Matsumi J, Shimizu H, Matsumi M, Morita K.
- Journal Title
  
  J Breath Res.
  
  Volume: 4(4) Pages: 47103-47103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592307
[Journal Article] Protective effect of carbon monoixide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2010
- Author(s)
  Kanagawa F, Takahashi T, Inoue K, Shimizu H, Omori E, Morimatsu H, Maeda S, Katayama H, Nakao A, Morita K.
- Journal Title
  
  J Trauma
  
  Volume: 69(1) Pages: 185-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592307
[Journal Article] Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats2010
- Author(s)
  Kanagawa F, Takahashi T, Inoue K, Shimizu H, Omori E, Morimatsu H, Maeda S, Katayama H, Nakao A, Morita K.
- Journal Title
  
  J Trauma
  
  Volume: 69 Pages: 185-194
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する2010
- Author(s)
  高橋徹
- Journal Title
  
  エンドトキシン研究
  
  Volume: 13 Pages: 65-68
- Data Source
  KAKENHI-PROJECT-21592307
[Journal Article] Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2010
- Author(s)
  Kanagawa F, Takahashi T, Shimizu H, Morita K, et al
- Journal Title
  
  Journal of Trauma
  
  Volume: 69 Pages: 185-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] An increase in exhaled CO concentration in systemic inflammation/sepsis.2010
- Author(s)
  Morimatsu, H., Takahashi, T., Matsusaki, T., Hayashi, M., Matsumi, J., Shimizu, H., Matsumi, M. and Morita, K.
- Journal Title
  
  J Breath Res
  
  Volume: 4 Pages: 47103-47103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592010
[Journal Article] An Increase in Exhaled CO Concentration in Systemic Inflammation/Sepsis.2010
- Author(s)
  Morimatsu H, Takahashi T, Shimizu H, Morita K, et al.
- Journal Title
  
  Journal of Breath Research
  
  Volume: 4(online publication) Pages: 47103-47103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Responses to surgical stress after esophagectomy : Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor-α and inducible nitric oxide synthase.2010
- Author(s)
  Suzuki S, Morimatsu, H, Omori E, Shimizu H, Takahashi T, Yamatsuji T, Naomoto Y, Morita K
- Journal Title
  
  MolecularMedicine Reports 3
  
  Pages: 765-769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Responses to surgical stress after esophagectomy: Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor-α and inducible nitric oxide synthase2010
- Author(s)
  Suzuki S, Morimatsu, H, Omori E, Shimizu H, Takahashi T, Yamatsuji T, Naomoto Y, Morita K.
- Journal Title
  
  Mol Med Rep
  
  Volume: 3 Pages: 765-769
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2010
- Author(s)
  Kanagawa F, Takahashi T, Inoue K, Shimizu H, Omori E, Morimatsu H, Maeda S, Katayama H, Nakao A, Morita K
- Journal Title
  
  The Journal of Trauma 69
  
  Pages: 185-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Role of heme oxygenase-1 in protection of the kidney after hemorrhagic shock.2010
- Author(s)
  Arimori Y, Takahashi T, Nishie H, Inoue K, Shimizu H, Omori E, Kawanishi S, Toda Y, Morimatsu H, Morita K
- Journal Title
  
  International Journal of Molecular Medicine 26
  
  Pages: 27-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] An Increase in Exhaled CO Concentration in Systemic Inflammation/Sepsis2010
- Author(s)
  Morimatsu H, Takahashi T, Matsusaki T, Hayashi M, Matsumi J, Shimizu H, Matsumi M, Morita K.
- Journal Title
  
  J Breath Res
  
  Volume: Vol. 4: Article ID 047103 Pages: 4-4
- Data Source
  KAKENHI-PROJECT-22591730
[Journal Article] Role of heme oxygenase-1 in protection of the kidney after hemorrhagic shock.2010
- Author(s)
  Arimori Y, Takahashi T, Nishie H, Inoue K, Shimizu H, Omori E, Kawanishi S, Toda Y, Morimatsu H, Morita K.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 26(1) Pages: 27-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592307
[Journal Article] Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxysenase-1 induction2009
- Author(s)
  Umeda K, Takahashi T, Shimizu K, Katayama H, Morita K
- Journal Title
  
  Shock 31
  
  Pages: 40-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Increased heme catabolism in critically ill patients : correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha concentrations2009
- Author(s)
  Morimatsu, H., Takahashi, T., Maeshima, K., Inoue, K., Kawakami, T., Shimizu, H., Takeuchi, M., Yokoyama, M., Katayama, H., Morita, K
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol Vol. 290, No. 1
  
  Pages: 114-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] (1th author, other 7 authors): Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock.2009
- Author(s)
  Takahashi T, Morimatsu H, Morita K, et. al.
- Journal Title
  
  J Clin Biochem Nutr Vol.44
  
  Pages: 28-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction2009
- Author(s)
  Umeda K, Takahashi T, Inoue K, Shimizu H, Maeda S, Morimatsu H, Omori E, Akagi R, Katayama H, Morita K
- Journal Title
  
  Shock 31
  
  Pages: 40-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Site-specific induction of intestinal hypoxia-inducible factor-1αafter hemorrhagic shock.2009
- Author(s)
  Nishie H, Takahashi T, Inoue K, Shimizu H, Morimatsu H, Toda Y, Omori E, Akagi R, Katayama H, Morita K.
- Journal Title
  
  Mol Med Rep 2
  
  Pages: 149-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Site-specific induction of intestinal hypoxia-inducible factor-lalpha after hemorrhagic shock2009
- Author(s)
  HIROYUKI NISHIE, TORU TAKAHASHI, HIROSHI MORIMATSU, KIYOSHI MORITA, et al.
- Journal Title
  
  Molecular Medicine Reports 2
  
  Pages: 149-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Prevention of hemorrhagic shock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction.2009
- Author(s)
  Umeda K, Takahashi T, Inoue K, Shimizu H, Maeda S, Morimatsu H, Omori E, Akagi R, Katayama H, Morita K.
- Journal Title
  
  Shock 31
  
  Pages: 40-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock2009
- Author(s)
  Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K. Heme
- Journal Title
  
  J Clin Biochem Nutr 44
  
  Pages: 28-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] (2nd author, other 6 authors) Prevention of hemorrhagicshock-induced intestinal tissue injury by glutamine via heme oxygenase-1 induction.2009
- Author(s)
  Umeda K, Takahashi T, Morimatsu H, Morita K, et. al.
- Journal Title
  
  Shock Vol.31
  
  Pages: 40-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock2009
- Author(s)
  Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K.
- Journal Title
  
  J Clin Biochem Nutr 44
  
  Pages: 28-40
- NAID
  130004466531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] (2nd author, other 6 authors): Protective effect of carbon monoxide inhalation on lung injury after hemorrhagic shock/resuscitation in rats.2009
- Author(s)
  Kanagawa F, Takahashi T, Morimatsu H, Morita K, et. al.
- Journal Title
  
  J Trauma (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock.2009
- Author(s)
  Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K.
- Journal Title
  
  J Clin Biochem Nutr 44
  
  Pages: 28-40
- NAID
  130004466531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Heme Oxygenase-1 is an Essential Cytoprotective Component in Oxidative Tissue Injury Induced by Hemorrhagic Shock2009
- Author(s)
  Takahashi T, Shimizu H, Morimatsu H, Maeshima K, Inoue K, Akagi R, Matsumi M, Katayama H, Morita K.
- Journal Title
  
  J Clin Biochem Nutr 44
  
  Pages: 28-40
- NAID
  130004466531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592010
[Journal Article] Hemin treatment abrogates monocrotaline-induced pulmonary hypertension2008
- Author(s)
  Shimzu K, Takahashi T, Matsumi M, et al.
- Journal Title
  
  Medicial Chemistry 4
  
  Pages: 572-576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Carbon Monoxide Ameliorates Renal Cold Ischemia-Reperfus ion Injury With an Upregulation of Vascular Endothelial Growth Factor by Activation of Hypoxia-Inducible Factor2008
- Author(s)
  Faleo G, Nakao A, Takahashi, T, et al.
- Journal Title
  
  Transplantation 85
  
  Pages: 1833-1840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Hemin treatment abrogates monocrotaline-induced pulmonary hypertension2008
- Author(s)
  Shimzu K, Takahashi T, Iwasaki T, Shimizu H, Inoue K, Morimatsu H, Omori E, Matsumi M, Akagi R, Morita K
- Journal Title
  
  Med Chem 4
  
  Pages: 572-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts.2008
- Author(s)
  Nakao A, Takahashi, T, et al
- Journal Title
  
  Kidney International 74
  
  Pages: 1009-1016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] 急性肺障害に対するウリナスタチンの治療効果のメカニズム2008
- Author(s)
  高橋徹
- Journal Title
  
  侵襲と免疫 17
  
  Pages: 91-98
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] 生体肝移植術中呼気一酸化炭素濃度の動態とその意義について2008
- Author(s)
  松崎孝、森松博史、高橋徹、林真雄、佐藤哲史、佐藤健治、清水裕子、松三昌樹、森田潔
- Journal Title
  
  日本Shock学会雑誌 23
  
  Pages: 85-89
- NAID
  10024300637
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] PROTECTIVE ROLE OF HEME OXYGENASE I IN THE INTESTINAL TISSUE INJURY IN HEMORRHAGIC SHOCK IN RATS2008
- Author(s)
  Inoue K, Takahashi T, Katayama H, et al.
- Journal Title
  
  SHOCK 29
  
  Pages: 252-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592120
[Journal Article] Increased exhaled carbon monoxide concentration during living donor liver transplantation2008
- Author(s)
  Matsusaki T, Morimatsu H, Takahashi T, Matsumi M, et al.
- Journal Title
  
  International Journal of Molecular Medicine 21
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Increased exhaled carbon monoxide concentration during living donor liver transplantation2008
- Author(s)
  Matsusaki T, Morimatsu H, Takahashi T, Matsumi M, Sato K, Kaku R, Sato T,Takahito Yagi, Tanaka N, Morita K
- Journal Title
  
  Int J Mol Med 21
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] ラット出血性ショック後急性肺傷害に対するウリナスタチンの治療効果2007
- Author(s)
  井上一由, 高橋徹, 片山浩, 他6名
- Journal Title
  
  日本Shock学会雑誌 22
  
  Pages: 96-99
- NAID
  10024300584
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] 酸化ストレスに対するヘムオキシゲナーゼ-1の臓器保護的役割2007
- Author(s)
  高橋徹、森松博史、森田潔, 他
- Journal Title
  
  日本薬理学会雑誌 130
  
  Pages: 252-256
- NAID
  10020167375
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] Heme Oxygenase-1: A Fundamental Guardian Against Oxidative Tissue Injuries in Acute Inflammation2007
- Author(s)
  T. Takahashi, H. H. Morimatsu, et. al.
- Journal Title
  
  Mini-Reviews in Medicinal Chemistry 7
  
  Pages: 745-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] ラット出血性ショック後急性肺傷害に対するウリナスタチンの治療効果2007
- Author(s)
  井上一由, 高橋徹, 井戸佳奈, 清水裕子, 森松博史, 前島亨一朗, 松三昌樹, 片山浩,森田潔
- Journal Title
  
  日本Shock学会雑誌 22
  
  Pages: 96-99
- NAID
  10024300584
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats.2007
- Author(s)
  Toda Y, Takahashi T, Morita K., et. al.
- Journal Title
  
  International Journal of Molecular Medicine 19
  
  Pages: 237-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591795
[Journal Article] ラット出血性ショック後急性肺傷害に対するウリナスタチンの治療効果2007
- Author(s)
  井上一由, 高橋徹, 片山浩, 他6名
- Journal Title
  
  Shock学会雑誌 22
  
  Pages: 96-99
- NAID
  10024300584
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇2007
- Author(s)
  高橋徹、片山浩, 他7名
- Journal Title
  
  エンドトキシン研究 10
  
  Pages: 65-68
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] Therapeutic effect of Urinary Trypsin Inhibitor on hemorrhagic-shock induced acute lung injury in rats2007
- Author(s)
  Kazuyoshi, Inoue, Toru, Takahashi, Kana, Ido, Hiroko, Shimizu, Hiroshi, Morimatsu, Kyoichiro, Maeshima, Hiroshi, Katayama, Kiyoshi, Morita
- Journal Title
  
  The Journal of Japan Shock Society Vol. 22, No. 2
  
  Pages: 96-99
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] 全身性炎症反応における呼気中一酸化炭素(CO)濃度の上昇2007
- Author(s)
  高橋徹、松三昌樹、他7名
- Journal Title
  
  エンドトキシン研究 10
  
  Pages: 65-68
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Increased heme catabolism in critically ill patients : correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha concentrations2006
- Author(s)
  Morimatsu H, Takahashi T, Katayama H, Morita K et al. (6 persons)
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 290・1
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity.2006
- Author(s)
  Kawakami T, Takahashi T, Katayama H, Morita K, Sassa S, et al.
- Journal Title
  
  International Journal of Molecular Medicine 18
  
  Pages: 537-46
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] Highly, liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity2006
- Author(s)
  Kawakami, T., Takahashi, T., Shimizu, H., Nakahira, K., Takeuchi, M., Katayama, H., Yokoyama, M., Morita, K., Akagi, R., Sassa, S
- Journal Title
  
  Int J Mol Med Vol. 18, No. 4
  
  Pages: 537-46
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] 敗血症性多臓器不全におけるストレス淡白 : ヘムオキシゲナーゼー1の発現とその意義2006
- Author(s)
  高橋徹, 松三昌樹, 森田潔他
- Journal Title
  
  エンドトキシン研究 9
  
  Pages: 70-75
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Heme oxygenase-1 : A new drug target in oxidative tissue injuries in critically ill conditions2006
- Author(s)
  Takahashi T, Shimizu H, Akagi R, Morita K, Sassa S.
- Journal Title
  
  Drug Development Research Vol. 67
  
  Pages: 130-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Defense against oxidative tissue injury : The essential role played by heme oxygenase-12006
- Author(s)
  Takahashi T, Morita K, Akagi R, Sassa S
- Journal Title
  
  Current Enzyme Inhibition 2
  
  Pages: 105-124
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Defense against oxidative tissue injury : The essential role played by heme oxygenase-12006
- Author(s)
  Takahashi T, Morito K, Akagi R, Sassa S
- Journal Title
  
  Current Enzyme Inhibition 2
  
  Pages: 105-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Heme arginate pretreatment attenuates pulmonary NF-KB and AP-1 Activation induced by hemorrhagic shock via heme oxygenase-1 induction2006
- Author(s)
  Sasaki T, Takahashi T, Maeshima K, Shimizu H, Toda Y, Morimatsu H, Takeuchi M, Yokoyama M, Akagi R, Morita K.
- Journal Title
  
  Medicinal Chemistry Vol. 2
  
  Pages: 271-274
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Heme oxygenase-1 : A New Drug Target in Oxidative Tissue Injuries in Critically III Conditions2006
- Author(s)
  Takahashi T, Shimizu H, Akagi R, Morita K, Sassa S
- Journal Title
  
  Drug Development Research 67
  
  Pages: 130-153
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] IIcmc Arginate Pretreatment Attenuates PuImonary NF-κB and AP-1 Activation Induced by Hemorrhagic Shock via Heme Oxygenase-1 Induction2006
- Author(s)
  T.Sasaki, T.Takahashi, et al.
- Journal Title
  
  Medicinal Chemistry 2
  
  Pages: 271-274
- Data Source
  KAKENHI-PROJECT-18591705
[Journal Article] Heme oxygenase-1 : A New Drug Target in Oxidative Tissue In juries in Critically 111 Conditions2006
- Author(s)
  Takahashi T, Shimizu H, Akagi R, Morita K, Sassa S
- Journal Title
  
  Drug Development Research 67
  
  Pages: 130-153
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Increased heme catabolism in critically ill patients: correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha conce ntrations2006
- Author(s)
  Morimatsu H, Takahashi T, Katayama H, Morita K, et. al. (6 persons)
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 290
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity.2006
- Author(s)
  Kawakami T, Takahashi T, Katayama H, Morita K, Sassa S, et. al.
- Journal Title
  
  Int J Mol Med 18
  
  Pages: 537-46
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591888
[Journal Article] Defense against oxidative tissue injury : The essential role played by heme oxygenase-l2006
- Author(s)
  Takahashi T, Morita K, Akagi R, Sassa S.
- Journal Title
  
  Current Enzyme Inhibition Vol. 2
  
  Pages: 105-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Heme arginate pretreatment attenuates pulmonary NF-κB and AP-1 Activation induced by hemorrhagic shock via heme oxygenase-1 induction2006
- Author(s)
  Sasaki T, Takahashi T, Morita K, et al.
- Journal Title
  
  Medicinal Chemistry 2
  
  Pages: 271-274
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats2005
- Author(s)
  Maeshima K, Takahashi T, Morita K, et al.
- Journal Title
  
  Biochemical Pharmacology 69
  
  Pages: 1667-1680
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] ショック研究の最前線-ヘムオキシゲナーゼとショック-2005
- Author(s)
  高橋徹, 森田潔
- Journal Title
  
  Anesthesia 21 Century 7・1-21
  
  Pages: 64-67
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Increased pulmonary home oxygenase-1 and delta-aminolerulinate synthase expression in monocrotaline-induced pulmonary hypertension2005
- Author(s)
  Iwasaki T, Takahashi T, Morita K, Akagi R, Kajiya F, et al.
- Journal Title
  
  Current Neurovascular Research 2・2
  
  Pages: 133-139
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats.2005
- Author(s)
  Maeshima K, Takahashi T, Morita K, et al.
- Journal Title
  
  Biochemical Pharmacology 69・11
  
  Pages: 1667-1680
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats.2005
- Author(s)
  Maeshima K, Takahashi T, Uehara K, Shimizu H, Omori E, Yokoyama M, Tani T, Akagi R, Morita K.
- Journal Title
  
  Biochemical Pharmacology Vol. 69
  
  Pages: 1667-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Cytoprotective effects of heme oxygenase in acute renal failure.2005
- Author(s)
  Akagi R, Takahashi T, Sassa S.
- Journal Title
  
  Contrib Nephrol 148
  
  Pages: 70-85
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] The lower intestinal tract-specific induction of home oxygnase-1 by glutamine protects against endotoxemic intestinal injury.2005
- Author(s)
  Uehara K, Takahashi T, Morita K, Akagi R, Sassa, et al.
- Journal Title
  
  Critical Care Medicine 33・2
  
  Pages: 381-390
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] Site- and cell-type- specific induction of intestinal inducible nitric oxide synthase in a rat model of endotoxemia2005
- Author(s)
  Takahashi T, Fujii H, Morita K, et al.
- Journal Title
  
  Medicinal Chemistry 1・6
  
  Pages: 643-647
- Data Source
  KAKENHI-PROJECT-16591542
[Journal Article] The effects of pretreatment with lidocaine or bupivacaine on the spatial and temporal expression of c真Fos protein in the spinal cord caused by plantar incision in the rat.2004
- Author(s)
  Xiaohui Sun, Masataka Yokoyama, Satoshi Mizobuchi, Rhuji Kaku, Hideki Nakatsuka, Toru Takahashi, Kiyoshi Morita
- Journal Title
  
  Anesthesia ＆ Analgesia 98
  
  Pages: 1093-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591543
[Journal Article] Protective role of an anti-inflammatory cytokine : Interleukin-11 on endotoxin-induced hepatic injury.2004
- Author(s)
  Takahashi T, Maeshima K, Katayama H, et al., 7 persons
- Journal Title
  
  Shock (Japan) Vol.19, No. 2
  
  Pages: 27-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591916
[Journal Article] The effects of pretreatment with lidocaine or bupivacaine on the spatial and temporal expression of c-Fos protein in the spinal cord caused by plantar incision in the rat.2004
- Author(s)
  Xiaohui Sun, Masataka Yokoyama, Satoshi Mizobuchi, Rhuji Kaku, Hideki Nakatsuka, Toru Takahashi, Kiyoshi Morita
- Journal Title
  
  Anesthesia ＆ Analgesia 98
  
  Pages: 1093-1098
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591543
[Journal Article] Comparison of percutaneous electrical nerve stimulation with transcutaneous electrical nerve stimulation for long-term pain relief in patients with chronic low back pain.2004
- Author(s)
  Masataka Yokoyama, Xiaohui Sun, Satoru Oku, Naoyuki Taga, Kenji Sato, Satoshi Mizobuchi, Toru Takahashi, Kiyoshi Morita
- Journal Title
  
  Anesthesia ＆ Analgesia 98
  
  Pages: 1552-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591543
[Journal Article] エンドトキシン投与急性肝障害モデルに対する抗炎症性サイトカイン:Interleukin-11の保護効果2004
- Author(s)
  高橋徹, 前島亨一郎, 他8名
- Journal Title
  
  日本Shock学会雑誌 19・2
  
  Pages: 27-32
- NAID
  10025680401
- Data Source
  KAKENHI-PROJECT-15591916
[Journal Article] A Protective Role of Interleukin 11 on Hepatic Injury in Acute Endotoxemia2004
- Author(s)
  Maeshima K, Takahashi T, Katayama H, et al., 7 persons
- Journal Title
  
  Shock Vol.21, No.2
  
  Pages: 134-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591916
[Journal Article] エンドトキシン投与急性肝障害モデルに対する抗炎症性サイトカイン:Interleukin-11の保護効果2004
- Author(s)
  高橋徹, 前島亨一郎, 片山浩, 他7名
- Journal Title
  
  日本Shock学会雑誌 19・2
  
  Pages: 27-32
- NAID
  10025680401
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591916
[Journal Article] The effects of pretreatment with lidocaine or bupivacaine on the spatial and temporal expression of c-Fas protein in the spinal cord caused by plantar incision in the rat2004
- Author(s)
  Sun X, Yokoyama M, Mizobuchi S, Kaku R, Nakatsuka H, Takahashi T, Morita K.
- Journal Title
  
  Anesthesia & Analgesia 98
  
  Pages: 1093-1098
- Data Source
  KAKENHI-PROJECT-16591543
[Journal Article] A Protective Role of Interleukin 11 on Hepatic Injury in Acute Endotoxemia.2004
- Author(s)
  Maeshima K, Takahashi T, Katayama H et al. 他7名
- Journal Title
  
  Shock 21・2
  
  Pages: 134-138
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591916
[Journal Article] 敗血症性急性肝障害に対する抗炎症性サイトカインInterleukin-11の治療効果2003
- Author(s)
  中平毅一, 高橋徹, 片山浩, 他8名
- Journal Title
  
  エンドトキシン研究 5
  
  Pages: 158-163
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591916
[Journal Article] Protective effect of interleukin-11 on septic hepatic injury2003
- Author(s)
  Nakahira K, Takahashi, T, Katayama H, et al., 8 persons
- Journal Title
  
  Endotoxin Research Vol.6
  
  Pages: 158-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591916
[Presentation] Protective effect of SnCl2 on rhabdomyolysis- induced acute kidney injury in rats2020
- Author(s)
  Shinkichi Ohtani, Hiroko Shimizu, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
- Organizer
  International Anesthesia Research Society 2020 ANNUAL MEETING
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08919
[Presentation] Protectove role of Carbon monoxide (CO)/CO-releasing molecule against acute respiratory distress syndrome induced by hemorrhagic shock and resuscitation2019
- Author(s)
  Toru Takahashi, Yuta Kumada, Hiroko Shimizu and Hiroshi Morimatsu
- Organizer
  23th International Symposium on Molecular Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10972
[Presentation] Carbon Monoxide-Releasing Molecule-3 Ameliorates Lung Injury after Hemorrhagic Shock and Resuscitation2017
- Author(s)
  Yuta Kumada, Hiroko Shimizu, Ryu Nakamura, Emiko Omori, Kazuyoshi Inoue, Toru Takahashi, Hiroshi Morimatsu
- Organizer
  The Anesthesiology Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10972
[Presentation] The effect of Dexmedetomidine on Lung Injury Induced by Hemorrhagic shock and Resuscitation in Rats2017
- Author(s)
  Nakamura R, Inoue I, Kumada Y, Shimizu H, Takahashi T, Morimatsu H
- Organizer
  Critical Care Congress
- Place of Presentation
  Hawaii Convention Center, Honolulu, Hawaii, USA
- Year and Date
  2017-01-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] Carbon Monoxide-releasing Molecule-3 Ameliorates Lung Injury after Hemorrhagic Shock and Resuscitation2017
- Author(s)
  Yuta Kumada, Toru Takahashi, Hiroko Shimizu, Ryu Nakamura, Emiko Omori, Kazuyoshi Inoue, Hiroshi Morimatsu,
- Organizer
  ANESTHESIOLOGY 2017 annual meeting
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] 出血性ショック蘇生時に投与したDexmedetomidineがラット蘇生後肺傷害に与える影響2017
- Author(s)
  中村龍, 井上一由, 熊田雄太, 清水裕子, 高橋徹, 森松博史
- Organizer
  第44回日本集中治療医学会学術集会
- Place of Presentation
  札幌市教育文化会館, 札幌市, 北海道
- Year and Date
  2017-03-09
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] Significant changes in renal Bach1 expression in　rhabdomyolysis-induced aute kidney injury.2017
- Author(s)
  Toru Takahashi, Masakazu Yamaoka, Hiroko Shimizu, Hiroshi Morimatsu
- Organizer
  20th International Symposium on Molecular Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] Significant changes in renal Bach1 expression in rhabdomyolysis-induced aute kidney injury2017
- Author(s)
  Toru Takahashi, Masakazu Yamaoka, Hiroko Shimizu and Hiroshi Moromatsu
- Organizer
  20th International Symposium on Molecular Medicine
- Invited
- Data Source
  KAKENHI-PROJECT-16K10972
[Presentation] Induction of Bach1 mRNA in a rat model of acute liver injury2016
- Author(s)
  Toru Takahashi
- Organizer
  19th International Symposium on Molecular Medicine
- Place of Presentation
  Athens, Greece
- Year and Date
  2016-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10972
[Presentation] The impact of fluid’s choice in early stage of hemorrhagic shock resuscitation on lung injury: Experimental animal study.2015
- Author(s)
  Ryu Nakamura, Kazuyoshi Inoue, Hiroko Shimizu, Toru Takahashi, Hiroshi Morimatsu
- Organizer
  The European Anesthesiology Congress(ESA)
- Place of Presentation
  CityCube Berlin (ドイツベルリン)
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] 敗血症によるラット急性肝傷害モデルおけ転写因子 Bach1 の動態2015
- Author(s)
  谷岡野人、清水裕子、高橋徹、山岡正和、森松博史
- Organizer
  日本麻酔科学会第 62 回学術集会
- Place of Presentation
  神戸ポートピアホテル (兵庫県神戸市)
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] Protective role of ulinastatin on lung injury and inflammation induced by hemorrhagic shock.2015
- Author(s)
  Toru Takahashi
- Organizer
  The 18th International Symposium on Molecular Medicine
- Place of Presentation
  Athens, Greece
- Year and Date
  2015-10-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462450
[Presentation] THE ROLE OF TRANSCRIPTION FACTOR BACH1 IN A RAT MODEL OF ACUTE LIVER INJURY INDUCED BY EXPERIMENTAL ENDOTOXEMIA2015
- Author(s)
  Nohito Tanioka, Hiroko Shimizu, Toru Takahashi, Emiko Omori, Masakazu Yamaoka, Ryu Nakamura, Hiroshi Morimatsu
- Organizer
  IARS(International Anesthesia Research Society) 2015 Annual Meeting and International Science Symposium
- Place of Presentation
  Hilton Hawaiian Village Resort・Honolulu・Hawaii, USA
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-24592735
[Presentation] 横紋筋融解症性急性腎傷害ラットモデルにおけるBach1発現とその意義2015
- Author(s)
  山岡正和、清水裕子、高橋徹、谷岡野人、黒田浩佐、中村龍、森松博史
- Organizer
  第42回日本集中治療医学会学術集会
- Place of Presentation
  東京都港区台場1-9-1　ホテル日航東京
- Year and Date
  2015-02-09
- Data Source
  KAKENHI-PROJECT-24592735
[Presentation] 活性酸素の関与とその制御―抗酸化ストレス蛋白HO-1システムの臨床応用への可能性. シンポジウム:肺傷害発症と重症化のメカニズム―臨床応用への可能性―2015
- Author(s)
  高橋　徹
- Organizer
  日本麻酔科学会・第62回学術集会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-25462450
[Presentation] DYNAMIC CHANGE IN BACH1 EXPRESSION IN A RAT MODEL OF GLYCEROL-INDUCED ACUTE KIDNEY INJURY2015
- Author(s)
  Masakazu Yamaoka, Hiroko Shimizu, Toru Takahashi, Emiko Omori, Nohito Tanioka, Ryu Nakamura, Hiroshi Morimatsu
- Organizer
  IARS(International Anesthesia Research Society) 2015 Annual Meeting and International Science Symposium
- Place of Presentation
  Hilton Hawaiian Village Resort・Honolulu・Hawaii, USA
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-24592735
[Presentation] 活性酸素の関与とその制御 ― 抗酸化ストレ蛋白 HO -1システムの臨床応用への可能性 ―2015
- Author(s)
  高橋徹
- Organizer
  日本麻酔科学会第 62 回学術集会
- Place of Presentation
  神戸ポートピアホテル (兵庫県神戸市)
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] The role of transcription factor Bach1 in a rat model of acute liver injury induced by experimental endotoxemia.2015
- Author(s)
  Nohito Tanioka, Hiroko Shimizu, Toru Takahashi, Masakazu Yamaoka, Hiroshi Morimatsu
- Organizer
  The European Anesthesiology Congress(ESA)
- Place of Presentation
  CityCube Berlin (ドイツベルリン)
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K10980
[Presentation] Protective role of heme oxygenase-1/CO system in hemorrhagic shock-induced acute lung injury2013
- Author(s)
  Toru Takahashi, Susumu Kawanishi, Jyunko Kosaka, Hiroko Shimizu, Hiroshi Morimatsu
- Organizer
  16th International Symposium on Molecular Medicine
- Place of Presentation
  Hotel Creta Maris Resort, Hersonissos, Crete, Greece
- Invited
- Data Source
  KAKENHI-PROJECT-24592735
[Presentation] Protective role of heme oxygenase-1/CO system in hemorrhagic shock-induced acute lung injury2013
- Author(s)
  Toru Takahashi, Susumu Kawanishi, Jyunko Kosaka, Hiroko Shimizu, Hiroshi Morimatsu
- Organizer
  16th International Symposium on Molecular Medicine
- Place of Presentation
  Hersonissos, Crete, Greece
- Invited
- Data Source
  KAKENHI-PROJECT-25462450
[Presentation] Increase in exhaled CO concentration after reperfusion of the grafted liver during living donor liver transplantation2012
- Author(s)
  Toru Takahashi, et al.
- Organizer
  15th International Symposium on Molecular Medicine
- Place of Presentation
  Crete, Greece
- Invited
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] 呼気COガスは酸化ストレスの指標か？2012
- Author(s)
  高橋　徹
- Organizer
  第１６回日本医療ガス学会学術大会
- Place of Presentation
  東京ステーションコンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] Induction of Bach1 messenger RNA in a rat model of acute liver injury2011
- Author(s)
  Shimizu H., Takahashi T., Omori E., Morimatsu H., Morita K.
- Organizer
  American Society of Anesthesiologists Annual Meeting
- Place of Presentation
  Chicago、ILLINOIS、USA
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21592307
[Presentation] ビリルビン・一酸化炭素は体に良いのですか?2011
- Author(s)
  高橋徹
- Organizer
  埼玉麻酔科専門医会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] GLUTAMINE-INDUCED HEME OXYGENASE-1 PROTECTS AGAINST INTESTINAL TISSUE INJURY IN A RAT MODEL OF HEMORRHAGIC SHOCK2011
- Author(s)
  Takahashi T, Morimatsu H, et al
- Organizer
  the 11th Joint Scientific Congress of Korean-Japanese Intensivist
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] 低濃度一酸化炭素吸入は自然免疫系の活性を抑制してラット出血性ショック後の急性肺障害を軽減する2010
- Author(s)
  川西進、高橋徹、清水裕子、小坂順子、森松博史、松三昌樹、森田潔
- Organizer
  第16回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  かしはら万葉ホール、奈良県橿原市
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21592307
[Presentation] 生体肝移植における肝Heme Oxygenase-1 mRNAと呼気一酸化炭素濃度の関係2010
- Author(s)
  松三絢弥、清水裕子、森松博史、高橋徹、森田潔
- Organizer
  日本麻酔学会年次総会
- Place of Presentation
  福岡
- Year and Date
  2010-06-03
- Data Source
  KAKENHI-PROJECT-21592010
[Presentation] Protective role of heme oxygenasse-1 induction in hemorrhagic shock-induced intestinal tissue injury2010
- Author(s)
  Toru Takahashi et al.
- Organizer
  The 10th Joint Scientific Congress of the KSCCM and JSICM
- Place of Presentation
  Hiroshima, Japan
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] ストレスと臓器保護～HO-1からCOまで～2010
- Author(s)
  高橋徹
- Organizer
  日本小児麻酔学会第16回学術集会
- Place of Presentation
  倉敷市芸文館
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] Protective role of heme oxygenasse-1 induction in hemorrhagic shock-induced intestinal tissue injury2010
- Author(s)
  高橋徹, 井上一由, 清水裕子, 森松博史, 片山浩, 森田潔
- Organizer
  The 10th Joint Scientific Congress of the KSCCM and JSICM
- Place of Presentation
  Hiroshima
- Year and Date
  2010-03-03
- Data Source
  KAKENHI-PROJECT-20592120
[Presentation] Bachlは酸化ストレスの指標になりうるか?2009
- Author(s)
  清水裕子、高橋徹、森田潔, 他2名
- Organizer
  第6回 Heme oxygenase研究フォーラム
- Place of Presentation
  京都府立医科大学青蓮会館(京都)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21592307
[Presentation] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する2009
- Author(s)
  高橋徹、井上一由, 清水裕子, 森松博史、楳田佳奈, 片山浩, 森田潔
- Organizer
  第15回日本エンドトキシン研究会
- Place of Presentation
  東京
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20592120
[Presentation] グルタミンはHO-1誘導を介して自然免疫系の活性化を抑制し出血性ショック後の腸管障害を軽減する2009
- Author(s)
  高橋徹、片山浩, 森田潔, 他
- Organizer
  日本エンドトキシン研究会
- Place of Presentation
  東京
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20592120
[Presentation] Bach1は酸化ストレスの指標になりうるか?2009
- Author(s)
  清水裕子、高橋徹、大森恵美子、森松博史、赤木玲子、森田潔
- Organizer
  第6回Heme Oxygenase研究ファーラム
- Place of Presentation
  京都府立医科大学青蓮会館、京都
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21592307
[Presentation] 低濃度CO吸入は出血性ショック誘発急性肺障害に対して治療効果を示す2009
- Author(s)
  金川文俊, 高橋徹, 井上一由, 清水裕子, 森松博史, 森田潔
- Organizer
  第56回日本麻酔科学会学術集会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19591795
[Presentation] Induction of Bach1 messenger RNA by heme-mediated oxidative stress2009
- Author(s)
  Shimizu H, Takahashi T, Omori E, Akagi R, Morita K.
- Organizer
  HEME OXYGENASES IN BIOLOGY AND MEDICINE 6th INTERNATIONAL CONGRESS ON HEME OXYGENASES
- Place of Presentation
  Maiami、Florida、USA
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21592307
[Presentation] INDUCTION OF BACH1 MESSENGER RNA BY HEME-MEDIATED OXIDATIVE STRESS2009
- Author(s)
  Hiroko Shimizu, Toru Takahashi, Kiyoshi Morita, 他2名
- Organizer
  HEME OXYGENASES IN BIOLOGY AND MEDICINE 6th INTERNATIONAL CONGRESS ON HEME OXYGENASES
- Place of Presentation
  Maiami, Florida, USA
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21592307
[Presentation] 生体肝移植における肝Heme Oxygenase-1RNAと呼気一酸化炭素濃度の関係2009
- Author(s)
  松三絢弥, 森松博史, 松崎孝, 高橋徹, 松三昌樹, 森田潔
- Organizer
  第56回日本麻酔科学会
- Place of Presentation
  神戸市
- Year and Date
  2009-08-16
- Data Source
  KAKENHI-PROJECT-21592010
[Presentation] ラット出血性ショック後腸管障害に対するHeme Oxygenase-1(HO-1)の細胞保護効果2009
- Author(s)
  高橋徹、清水裕子、井上一由、森松博史、片山浩、森田潔
- Organizer
  第24回日本Shock学会総会
- Place of Presentation
  金沢市
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-20592120
[Presentation] Relationship between exhaled carbon monoxide and oxidative stress in ischemic-reperfusion injury during living donor liver transplantation2009
- Author(s)
  Matsumi J, Moritasu H, Shimizu H, Takahashi T, Morita K.
- Organizer
  Annual meeting of the European Society of Anesthesiologists
- Place of Presentation
  ミラノ
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-21592010
[Presentation] PROTECTIVE ROLE OF HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM IN PULMONARY INJURY AND INFLAMMATION2008
- Author(s)
  Toru Takahashi
- Organizer
  The nth International Symposium on Molecular Medicine
- Place of Presentation
  Creta Mar is Hotel, Crete, Greece
- Year and Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-19591795
[Presentation] HO-1は出血性ショックによる自然免疫系の活性化を抑制し腸管を保護する2008
- Author(s)
  高橋徹, 片山浩, 森田潔, 他
- Organizer
  日本エンドトキシン研究会
- Place of Presentation
  仙台市艮陵会館
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-20592120
[Presentation] PROTECTIVE ROLE OF HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM IN PULMONARY INJURY AND INFLAMMATION2008
- Author(s)
  Toru Takahashi
- Organizer
  The 11th International Symposium on Molecular Medicine
- Place of Presentation
  Crete, Greece
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19591795
[Presentation] HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM: A NOVEL MOLECULAR TARGET AGAINST OXIDAITVE TISSUE INJURIES2007
- Author(s)
  Toru Takahashi
- Organizer
  The 10th International Symposium on Molecular Medicine
- Place of Presentation
  Crete, Greece
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19591795
[Presentation] Peak Exhaled Carbon Monoxide Concentration and Hyperbilirubinemia after Liver Transplantation2007
- Author(s)
  Matsusaki, T., Matsumi, M., Takahashi, T., et. al.
- Organizer
  Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San francisco, USA
- Year and Date
  2007-10-13
- Data Source
  KAKENHI-PROJECT-18591705
[Presentation] IL-11 protects carbon tetrachloride-induced hepatic injury by stabilizing heme protein2007
- Author(s)
  Takahashi, T., Kawakami, T., Shimizu, H., Inoue, K., Morimatsu, H., Katayama, H., Matsumi, M., Morita, K
- Organizer
  The 22th Annual Meeting of Japan Shock Society
- Place of Presentation
  Shiga, Japan
- Year and Date
  2007-05-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591888
[Presentation] IL-11はヘム蛋白安定化作用により四塩化炭素肝障害に対して保護作用を示す2007
- Author(s)
  高橋徹、片山浩、他6名
- Organizer
  日本Shock学会総会
- Place of Presentation
  滋賀県大津市
- Year and Date
  2007-05-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591888
[Presentation] Protective Role Played by HO-1 Gene Expression and CO in Critically Ill Conditions2007
- Author(s)
  Toru Takahashi
- Organizer
  The 5th International Congress Heme Oxygenases 2007
- Place of Presentation
  Krakow, Poland
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19591795
[Presentation] HEME OXYGENASE-1/CARBON MONOXIDE SYSTEM: A NOVEL MOLECULAR TARGET AGAINST OXIDAITVE TISSUE INJURIES2007
- Author(s)
  Toru Takahashi
- Organizer
  The 10th International Symposium on Molecular Medicine
- Place of Presentation
  Creta Maris Hotel, Crete, Greece
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19591795
[Presentation] GLUTAMINE-INDUCED HEME OXYGENASE-1 PROTECTS AGAINST INTESTINAL TISSUE INJURY IN A RAT MODEL OFHEMORRHAGIC SHOCK
- Author(s)
  Toru Takahashi et al
- Organizer
  Joint Scientific Congress of Korean-Japanese Intensivist
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] 四塩化炭素投与によるラット急性肝傷害における肝Bach1遺伝子の発現
- Author(s)
  谷岡野人, 清水裕子, 高橋徹, 山岡正和, 森松博史
- Organizer
  第41回日本集中治療医学会学術集会
- Place of Presentation
  国立京都国際会館 (京都府京都市左京区)
- Data Source
  KAKENHI-PROJECT-24592735
[Presentation] Increase in exhaled CO concentration after reperfusion of the grafted liver during living donor liver transplantation
- Author(s)
  Toru Takahashi, et al
- Organizer
  15th International Symposium on Molecular Medicine
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-22591730
[Presentation] Induction of Bach1 messenger RNA in the graft liver after reperfusion during living donor liver transplantation
- Author(s)
  Hiroko Shimizu1, Toru Takahashi, Junya Matsumi, Ph.D., Emiko Omori, Takashi Matsuzaki, Hiroshi Morimatsu, Kiyoshi Morita
- Organizer
  American Society of Anesthesiologists Annual Meeting
- Place of Presentation
  Walter E. Washington Convention Center Washington, DC, United States
- Data Source
  KAKENHI-PROJECT-24592735

1. MORITA Kiyoshi (40108171)

# of Collaborated Projects: 13 results

# of Collaborated Products: 98 results
2. SHIMIZU Hiroko (80423284)

# of Collaborated Projects: 10 results

# of Collaborated Products: 72 results
3. MORIMATU Hiroshi (30379797)

# of Collaborated Projects: 9 results

# of Collaborated Products: 48 results
4. MIZOBUCHI Satoshi (70311800)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
5. HIRAKAWA Masahisa (70033058)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. AKAGI Reiko (50150967)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. MATSUMI Masaki (70219476)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
8. KATAYAMA Hiroshi (90161067)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
9. NAKATSUKA Hideki (70263580)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. OGINO Tetsuya (90252949)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. OHMORI Emiko

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
12. YOKOYAMA Masataka (20158380)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. NINOMIYA Yoshifumi (70126241)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 井上一由 (10624413)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
15. FUJITA Hiroyoshi (60142931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJII Yoshiaki (00098146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MAEDA Shigeru (50253000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. YAMAAI Yuichiro (00158057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MIYAWAKI Takuya (00219825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山田輝夫 (00033225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 多賀直行 (20346456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 竹内護 (60284113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 梶谷文彦 (70029114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 岩崎達雄 (60379766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 高橋恭子 (50292008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YAMAOKA Masakazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
27. GASSMANN Max

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. FANDREY Joac

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 佐々茂

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. SYTKOWSKI Ar

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 坂本寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 末田慎二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 東元祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 平順一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 小松英幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI Tooru 高橋 徹

Research Projects

Research Products

Co-Researchers

ドラッグ・リポジショニングを応用した急性呼吸窮迫症候群に対する薬物療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of mitophagy in the therapy of CO-releasing molecule against acute respiratory distress syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of biliverdin/bilirubin redox cycle to the novel therapeutic strategy against acute lung injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of therapeutic and anti-inflammatory effect of carbon monoxide inhalation against acute lung injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of CO inhalation therapy for acute lung injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

TAKAHASHI Tooru 高橋徹