Nishitani Hideo 西谷秀男

… Alternative Names

NISITANI Hidbo 西谷秀男

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Researcher Number	40253455
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2022: 兵庫県立大学, 理学研究科, 教授 2020: 兵庫県立大学, 生命理学研究科, 教授 2012 – 2017: 兵庫県立大学, 生命理学研究科, 教授 2007 – 2011: University of Hyogo, Grad. Sch. of Life Sci, Professor 2009: 兵庫県立大学, 大学院・生命理学, 教授 … More 2008: 兵庫県立大学, 大学院・生命理学研究所, 教授 2007: University of Hyogo, 生命理学研究科, 教授 2007: 兵庫県立大学大学院, 生命理学研究科, 教授 2006: 九州大学, 医学研究院, 助手 2005 – 2006: 九州大学, 大学院医学研究院, 助手 2000 – 2005: 九州大学, 大学院・医学研究院, 助手 1999: Kyushu University, Graduate School of Medical Science, Research Associate, 大学院・医学系研究科, 助手 1998: 九州大学, 大学院医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Cell biology / Biological Sciences / Basic Section 43030:Functional biochemistry-related / Molecular biology / Functional biochemistry / Molecular biology Except Principal Investigator Biological Sciences / General anatomy (including Histology/Embryology) / General medical chemistry / Biological Sciences
Keywords	Principal Investigator 細胞周期 / 複製 / 分解 / タンパク質分解 / ユビキチン / DNA複製 / タンパク質 / Cdt1 / ライセンス化 / ゲノム … More / DNA損傷 / DNA / Geminin / PCNA / 修復 / 染色体 / Skp2 / CDK / がん / リン酸化 / Cdt2 / ゲノム情報 / ubiauitin / replication / Aroteolvsis / Cell Cycle / Proteolysis / Cell cycle / Replication / スピンドル / 紡錘体 / 核酸 / ゲノムDNA / 癌 / タンパクー質 / ユビキチンープロテアソーム系 / CyclinA / Cdtl / cdc18 / cdt1 / ガン / ゲノムサイズ … More Except Principal Investigator Ran / RCC1 / Mog1 / RanBP2 / RanBP1 / DAD1 / HCF / 遺伝子 / Cdt1 / 細胞周期 / MOG1 / RagA / RanBPM / 細胞周期制御 / ATR / Xenonus laevis / G protein / Genetics / Ultrastructure of the cell / Cell Histology / Anatomy / Xenopus leavis / Xenopus laevis / G蛋白質 / 細胞微細形態学 / 細胞・組織 / 解剖学 / retrovirus vector / genetically engineered mice / molecular basis / stemness / stem cells / Polycomb-group genes / Geminin / DNA複製制御 / 造血幹細胞 / 成体幹細胞 / レトロウイルスベクター / 遺伝子改変マウス / 分子基盤 / 幹細胞性 / 幹細胞 / ポリコーム遺伝子群 / cell cycle / アポプトーシス / Cdc25B / Crmlp / Yrb2p / Gtrlp / Rcclp / YRB2 / DIS3 / GTR1 / アポトーシス / Yrb2 / DNA複製 / 染色体 / ゲノム / 分子生物学 / TRF2 / 染色体不安定性 / テロメア / タンパク質分解制御 / ORC / 複製チェックポイント / CDC6 / CRL4ユビキチンリガーゼ / クロマチンリモデリング / SNF2H / 染色体安定性 / クロマチン / 染色体DNA複製 / RagA,B,C,D / Gtr2p / Gtr1p / Cell Cycle / Gtr1 / Gap1 / DBX / SNF2 / H3-K9メチル転移酸素 / Adenine / カフェイン / NTF2 / 温度感受性変異マウス / ヘテロクロマチン / Histone H3-K9 methyltransferase / RanGAP Less

Mechanism of DNA synthesis-activated proteolysis for genome integrityPrincipal Investigator
- Principal Investigator
  
  Nishitani Hideo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  University of Hyogo
Regulation of DNA replication through proteolysis coupled with PCNA cyclePrincipal Investigator
- Principal Investigator
  
  Nishitani Hideo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Hyogo
Coupling of spindle checkpoint with initiation of DNA replicationPrincipal Investigator
- Principal Investigator
  
  Nishitani Hideo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  University of Hyogo
修復と複製時に機能するCul4-DDB1-Cdt2によるゲノム維持機構Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
Ｍ期ＤＮＡ損傷の修復系とＤＮＡ複製開始制御の連係機構の解析Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
タンパク質分解系による複製のライセンシング確立の制御機構Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
Regulation of genome integrity through a DNA replication coupled feedback controlPrincipal Investigator
- Principal Investigator
  
  NISHITANI Hideo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  University of Hyogo
UV照射後に活性化されるCul4-DDB1-Cdt2によるCdt1分解機構の解析Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
タンパク質分解による複製のライセンス化制御Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
DNA複製と連係したタンパク質分解機構の解明(p21Cip1を中心に)Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
Study on the novel S-phase specific proteolysis pathwayPrincipal Investigator
- Principal Investigator
  
  NISHITANI Hideo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  University of Hyogo
  Kyushu University
Molecular anatomical research of nuclear membrane in mitotic phase : the ultra structure of the surface and genes regulate it.
- Principal Investigator
  
  HIROSE Eiji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyushu University
Molecular mechanisms for pre-replication complexes assembly and its implication in chromosomal stability in mammalian cells
- Principal Investigator
  
  FUJITA Masatoshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
細胞周期における染色体複製ライセンス化因子の制御機構の解析Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Role of Polycomb-group genes in adult stem cells and their expansion
- Principal Investigator
  
  TAKIHARA Yoshihiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  HIROSHIMA UNIVERSITY
染色体複製開始因子の制御機構から捉えた細胞増殖とがん化の研究Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
染色体複製のライセンス化と細胞周期制御の解明―CDT1を中心に―Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Cell cycle regulation of DNA replication licensing factor Cdt1Principal Investigator
- Principal Investigator
  
  NISHITANI Hideo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
体細胞の細胞周期とその制御機構-RCC1-RanGTPaseの解析を中心として-
- Principal Investigator
  
  NISHIMOTO Takeharu
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
染色体複製のライセンス化異常と細胞のガン化Principal Investigator
- Principal Investigator
  
  西谷秀男
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Regulation of cell cycle in the somatic cells
- Principal Investigator
  
  NISHIMOTO Takeharu
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  KYUSHU UNIVERSITY

[Book] タンパク質分解系による染色体の再複製抑制機構実験医学(増刊)　細胞周期2013
- Author(s)
  西谷秀男
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23131512
[Book] CDKインヒビターp21の分解による細胞周期の制御生体の科学2009
- Author(s)
  塩見泰史、西谷秀男、釣本俊樹
- Data Source
  KAKENHI-PROJECT-21370081
[Book] 染色体サイクル Cdt1タンパク質によるpre-RC形成と再複製の抑制制御2007
- Author(s)
  西谷秀男
- Total Pages
  6
- Publisher
  実験医学羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Book] 細胞周期イラストマップ:DNA複製のライセンス化制御2005
- Author(s)
  西谷秀男
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16026233
[Journal Article] CRL4 Cdt2 Ubiquitin Ligase, A Genome Caretaker Controlled by Cdt2 Binding to PCNA and DNA2022
- Author(s)
  Mazian MA, Yamanishi K, Rahman MZA, Ganasen M, Nishitani H.
- Journal Title
  
  Genes (Basel)
  
  Volume: 13(2) Issue: 2 Pages: 266-266
- DOI
  10.3390/genes13020266
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06547
[Journal Article] CRL4(Cdt2): Coupling Genome Stability to Ubiquitination2020
- Author(s)
  Panagopoulos A, Taraviras S, Nishitani H, Lygerou Z.
- Journal Title
  
  Trends Cell Biol.
  
  Volume: 30 Issue: 4 Pages: 290-302
- DOI
  10.1016/j.tcb.2020.01.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06547
[Journal Article] Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase.2018
- Author(s)
  Nukina K, Hayashi A, Shiomi Y, Sugasawa K, Ohtsubo M, Nishitani H.
- Journal Title
  
  Genes Cells.
  
  Volume: 23 Issue: 3 Pages: 200-213
- DOI
  10.1111/gtc.12563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07257, KAKENHI-PROJECT-26291025, KAKENHI-PUBLICLY-16H01311, KAKENHI-PROJECT-16H06307
[Journal Article] Mismatch repair proteins recruited to ultraviolet light-damaged sites lead to degradation of licensing factor Cdt1 in the G1 phase.2017
- Author(s)
  Tanaka M, Takahara M, Nukina K, Hayashi A, Sakai W, Sugasawa K, Shiomi Y, Nishitani H.
- Journal Title
  
  Cell Cycle
  
  Volume: 16 Issue: 7 Pages: 673-684
- DOI
  10.1080/15384101.2017.1295179
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291025, KAKENHI-PROJECT-16K07257
[Journal Article] Thymine DNA glycosylase modulates the DNA damage response and gene expression by base excision repair-dependent and -independent mechanisms2017
- Author(s)
  Tomohumi Nakamura, Kouichi Murakami, Haruto Tada, Yoshihiko Uehara, Jumpei Nogami, Kazumitsu Maehara, Yasuyuki Ohkawa, Hisato Saitoh, Hideo Nishitani, Tetsuya Ono, Ryotaro Nishi, Masayuki Yokoi, Wataru Sakai, and Kaoru Sugasawa
- Journal Title
  
  Genes to Cells
  
  Volume: 22 Issue: 4 Pages: 392-405
- DOI
  10.1111/gtc.12481
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05888, KAKENHI-PROJECT-17K19356, KAKENHI-PROJECT-26291025, KAKENHI-PUBLICLY-16H01311, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H06307, KAKENHI-PROJECT-17H03608, KAKENHI-PROJECT-16K18479, KAKENHI-PROJECT-17H01878
[Journal Article] Control of Genome Integrity by RFC Complexes; Conductors of PCNA Loading onto and Unloading from Chromatin during DNA Replication.2017
- Author(s)
  Shiomi Y, Nishitani H.
- Journal Title
  
  Genes
  
  Volume: 8 Issue: 2 Pages: 52-52
- DOI
  10.3390/genes8020052
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291025, KAKENHI-PROJECT-26650064, KAKENHI-PROJECT-16K07257
[Journal Article] Mitotic UV Irradiation Induces a DNA Replication-Licensing Defect that Potentiates G1 Arrest Response.2015
- Author(s)
  Morino M, Nukina K, Sakaguchi H, Maeda T, Takahara M, Shiomi Y, Nishitani H.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0120553-e0120553
- DOI
  10.1371/journal.pone.0120553
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25131718, KAKENHI-PROJECT-25430171, KAKENHI-PROJECT-26291025
[Journal Article] Imaging analysis of cell cycle-dependent degradation of Cdt1 in mammalian cells.2014
- Author(s)
  Shiomi Y, Suenaga N, Tanaka M, Hayashi A, Nishitani H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1170 Pages: 357-65
- DOI
  10.1007/978-1-4939-0888-2_18
- ISBN
  9781493908875, 9781493908882
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J07320, KAKENHI-PUBLICLY-25131718
[Journal Article] Imaging analysis to determine chromatin binding of licensing factors MCM2-7 in mammalian cells.2014
- Author(s)
  Mayayuki Morino, Miyuki Tanaka, Yasuhi Shiomi, Hideo Nishitani
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1170 Pages: 529-537
- DOI
  10.1007/978-1-4939-0888-2_29
- ISBN
  9781493908875, 9781493908882
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25131718, KAKENHI-PROJECT-26291025
[Journal Article] Chromatin fractionation analysis of licensing factors in mammalian cells.2014
- Author(s)
  Hideo Nishitani, Masayuki Morino, Yusuke Murakami, Takeshi Maeda, Yasushi Shiomi
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1170 Pages: 517-527
- DOI
  10.1007/978-1-4939-0888-2_28
- ISBN
  9781493908875, 9781493908882
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26650064
[Journal Article] PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells.2014
- Author(s)
  Hayashi A, Suenaga N, Shiomi Y, Nishitani H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1170 Pages: 367-82
- DOI
  10.1007/978-1-4939-0888-2_19
- ISBN
  9781493908875, 9781493908882
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J07320, KAKENHI-PROJECT-26291025
[Journal Article] Alternative replication factor C protein, Elg1, maintains chromosome stability by regulating PCNA levels on chromatin2013
- Author(s)
  Shiomi Y, Nishitani H
- Journal Title
  
  Genes Cells
  
  Volume: 18 Issue: 11 Pages: 946-959
- DOI
  10.1111/gtc.12087
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25131718, KAKENHI-PROJECT-25430171
[Journal Article] Cell Cycle-dependent Subcellular Translocation of the Human DNA Licensing Inhibitor Geminn2013
- Author(s)
  Dimaki M, Xouri G, Symeonidou IE, Sirinian C, Nishitani H, Taraviras S, Lygerou Z.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Issue: 33 Pages: 23953-23963
- DOI
  10.1074/jbc.m113.453092
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25131718
[Journal Article] Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.2012
- Author(s)
  Suzuki T
- Journal Title
  
  J Biol Chem
  
  Volume: Nov 23;287(48) Issue: 48 Pages: 40256-40265
- DOI
  10.1074/jbc.m112.353805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-23247031, KAKENHI-PROJECT-23657081, KAKENHI-PUBLICLY-23121506, KAKENHI-PUBLICLY-23131512, KAKENHI-PUBLICLY-24114520
[Journal Article] Two different RFC proteins, Ctf18 and RFC1 separetely control PCNA-CRL4Cdt2-mediated Cdtl proteolysis during S phase and following UV-irradiation.2012
- Author(s)
  Shiomi Y, Hayashi A, Ishii T, Shinmyozu K, Nakayama JI, Sugasawa K, Nishitani H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 Pages: 2279-2288
- Data Source
  KAKENHI-PROJECT-21370081
[Journal Article] Checkpoint Kinase ATR Phosphorylates Cdt2, a Substrate Receptor of CRL4 Ubiquitin Ligase, and Promotes the Degradation of Cdt1 following UV-irradiation2012
- Author(s)
  Hiroki Sakaguchi, Toshihiro Takami, Yoshinori Yasutani, Takeshi Maeda, Masayuki Morino, Takashi Ishii, Yasushi Shiomi, Hideo Nishitani
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 9 Pages: e46480-e46480
- DOI
  10.1371/journal.pone.0046480
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23131512
[Journal Article] Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs2012
- Author(s)
  Stathopoulou A, Roukos V, Petropoulou C, Kotsantis P, Karantzelis N, Nishitani H, Lygerou Z, Taraviras S
- Journal Title
  
  PLoS One
  
  Volume: 7(3)
- Data Source
  KAKENHI-PROJECT-21370081
[Journal Article] Two different RFC proteins, Ctf18 and RFC1 separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV-irradiation2012
- Author(s)
  Shiomi Y, Ishii T, Hayashi A, Shinmyozu K, Nakayama J, Sugasawa K, & Nishitani H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 Issue: 12 Pages: 2279-88
- DOI
  10.1128/mcb.06506-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370004, KAKENHI-PROJECT-24241019, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114005, KAKENHI-PLANNED-23116008, KAKENHI-PUBLICLY-23131512
[Journal Article] Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage2011
- Author(s)
  Roukos V, Kinkhabwala A, Colombelli J, Kotsantis P, Taraviras S, Nishitani H, Stelzer E, Bastiaens P, Lygerou Z
- Journal Title
  
  J Cell Sci
  
  Volume: 124 Pages: 422-434
- Data Source
  KAKENHI-PROJECT-21370081
[Journal Article] Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2)-mediated proteolysis2011
- Author(s)
  Michishita M, Morimoto A, Ishii T, Komori H, Shiomi Y, Higuchi Y, Nishitani H
- Journal Title
  
  Genes Cells
  
  Volume: 16(1) Pages: 12-22
- Data Source
  KAKENHI-PROJECT-21370081
[Journal Article] Proliferating cell nuclear antigen-dependent rapid recruitment of Cdt1 and CRL4Cdt2 at DNA-damaged sites after UV irradiation in HeLa cells2010
- Author(s)
  Ishii T, Shiomi Y, Takami T, Murakami Y, Ohnishi N, Nishitani H
- Journal Title
  
  J Biol Chem
  
  Volume: 285(53) Pages: 41993-42000
- Data Source
  KAKENHI-PROJECT-21370081
[Journal Article] CDK inhibitor p21 is degraded by a PCNA coupled Cu14-DDB1Cdt2 nathwav rinrinu S nhase and after UV irradiation2008
- Author(s)
  Nishitani H, et.al.
- Journal Title
  
  J Biol. Chem 283
  
  Pages: 29045-29052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20058030
[Journal Article] CDK inhibitor p21 is degraded by a PCNA coupled Cu14-DDB1Cdt2 pathway during S phase and after UV irradiation2008
- Author(s)
  Nishitani H, et.al.
- Journal Title
  
  J Biol. Chem 283
  
  Pages: 29045-29052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012047
[Journal Article] CDK inhibitor p21 is degraded by a PCNA coupled Cu14-DDB1Cdt2 pathway during S phase and after UV irradiation2008
- Author(s)
  Nishitani H, et.al.
- Journal Title
  
  J Biol. Chem 283
  
  Pages: 29045-29052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044031
[Journal Article] CDK inhibitor p21 is degraded by a PCNA coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation.2008
- Author(s)
  Nishitani H, Shiomi Y, Iida H, Michishita M, Takami T, Tsurimoto T.
- Journal Title
  
  J. B i o l. C h e m. 283
  
  Pages: 29045-29052
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] CDK inhibitor p21 is degraded by a profilerating cell nuclear antigen-coupled Cu14-DDB1Cdt2 pathway during S phase and after UV irradiation2008
- Author(s)
  Hideo Nishitani
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 29045-29052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] Cdtl associates dynamically with chromatin throughout Gl and recruits Geminin onto chromatin.2007
- Author(s)
  Xourl G, Squire A, Dinaki M, Geverts B, Verveor PJ, Teraviras S, Nishitani H, Houtsmuller AB, Bastlsens PI, Lygerou Z.
- Journal Title
  
  EMBO J. 26(5)
  
  Pages: 1303-1314
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Control of pre-RC formation and prevention of re-replication through regulating licensing factor Cdtl2007
- Author(s)
  Nishitani, H
- Journal Title
  
  Experimental Medicine 25
  
  Pages: 31-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Cdtl associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin2007
- Author(s)
  Xouri G, Squire A, Dimaki M, Geverts B, Verveer PJ, Taraviras S, Nishitani H, Houtsmuller AB, Bastiaens PI, Lygerou Z
- Journal Title
  
  EMBO J 26(5)
  
  Pages: 1303-14
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin.2007
- Author(s)
  Xouri G, Squire A, Dimaki M, Geverts B, Verveer PJ, Taraviras S, Nishitani H, Houtsmuller AB, Bastiaens PI, Lygerou Z.
- Journal Title
  
  E M B O J. 26
  
  Pages: 1303-1314
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] Licensing regulators Geminin and Cdtl identify progenitor cells of the mouse CNS in a specific phase of the cell cycle2007
- Author(s)
  Spella M, Britz O, Kotantaki P, Lygerou Z, Nishitani H, Ramsay RG, Flordellis C, Guillemot F, Mantamadiotis T, Taraviras S.
- Journal Title
  
  Neuroscience 147(2)
  
  Pages: 373-87
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle2007
- Author(s)
  Spella M, Britz O, Kotantaki P, Lygerou Z, Nishitani H, Ramsay, RG, Flordellis C, Guillemot F, Mantamadiotis T, Taraviras, S
- Journal Title
  
  Neuroscience 147(2)
  
  Pages: 373-387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Abstract Identification of a heat-shock protein Hsp40, DjB1, as an acrosome- and a tail-associated component in rodent spermatozoa.2007
- Author(s)
  Doiguchi M, Kaneko T, Urasoko A, Nishitani H, Iida H.
- Journal Title
  
  Mol. Reprod. Dev. 74(2)
  
  Pages: 223-232
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma.2007
- Author(s)
  Roukos V, Iliou MS, Nishitani H, Gentzel M, Wilm M, Taraviras S, Lygerou Z.
- Journal Title
  
  J. Biol. Chem. 282(13)
  
  Pages: 9346-9357
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Cdtl associates dynamically with chromatin throughout Gl and recruits Geminin onto chromatin2007
- Author(s)
  Xouri, G., Squire, A., Dimaki, M., Geverts, B., Verveer, PJ., Taraviras, S., Nishitani, H., Houtsmuller, AB., Bastiaens, BI., Lygerou, Z
- Journal Title
  
  EMBO J 26(5)
  
  Pages: 1303-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle2007
- Author(s)
  Spella M, Britz O, Kotantaki P, Lygerou Z, Nishitani H, Ramsay RG, Flordeilis C, Guillemot F, Mantamadiotis T, Taraviras S.
- Journal Title
  
  Neuroscience 147(2)
  
  Pages: 373-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Temperature-sensitive defects of the GSP1gene, yeast Ran homologue, activate the Tell-dependent pathway.2007
- Author(s)
  Hayashi N, Murakami S, Tsurusaki S, Nagaura Z, Oki M, Nishitani H, Kobayashi M, Shimizu H, Yamamoto K, Nishimoto T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 353(2)
  
  Pages: 330-336
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma2007
- Author(s)
  Roukos V, Iliou, MS, Nishitani H, Gentzel M, Wilm M, Taraviras S, Lygerou, Z
- Journal Title
  
  J Biol Chem 282(13)
  
  Pages: 9346-9357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Cdtl associates dynamically with chromatin throughout GI and recruits Geminin onto chromatin2007
- Author(s)
  Xouri G, Squire A, Dimaki M, Geverts B, Verveer, PJ, Taraviras S, Nishitani H, Houtsmuller, AB, Bastiaens, PI, Lygerou, Z
- Journal Title
  
  EMBO J 26(5)
  
  Pages: 1303-1314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Licensing regulators Geminin and Cdtl identify progenitor cells of the mouse CNS in a specific phase of the cell cycle2007
- Author(s)
  Spella, M., Britz, O., Kotantaki, P., Lygerou, Z., Nishitani, H., Ramsay, RG., Flordellis, C., Guillemot, F., Mantamadiotis, T., Taraviras, S
- Journal Title
  
  Neuroscience 147(2)
  
  Pages: 373-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.2006
- Author(s)
  Hideo Nishitani
- Journal Title
  
  EMOBO J. 25
  
  Pages: 1126-1136
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis2006
- Author(s)
  Nishitani H et al.
- Journal Title
  
  EMBO J. 25
  
  Pages: 1126-1136
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cu14, target human Cdt1 for proteolysis.2006
- Author(s)
  Hideo Nishitani
- Journal Title
  
  EMBO J. 25
  
  Pages: 1126-1136
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and C1r4 histone methyltransferase in Schizosaccharomyces pombe2006
- Author(s)
  Nishijima H, Nakayama J, Yoshioka T, Kusano A, Nishitani H, Shibahara K, Nishimoto, T
- Journal Title
  
  Mol. Biol. Cell 17
  
  Pages: 2524-2536
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] wo E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.2006
- Author(s)
  Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama K-I, Nakayama K, Fujita M, Lygerous Z, Nishimoto T.
- Journal Title
  
  E M B O J. 25
  
  Pages: 1126-1136
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe.2006
- Author(s)
  Nishijima H, Nakayama J, Yoshioka T, Kusano A, Nishitani H, Shibahara K, Nishimoto T.
- Journal Title
  
  Mol. Biol. Cell 17(6)
  
  Pages: 2524-2536
- Data Source
  KAKENHI-PROJECT-18590188
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis2006
- Author(s)
  Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama, KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto, T
- Journal Title
  
  EMBO J 25
  
  Pages: 1126-1136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdtl for proteolysis2006
- Author(s)
  Nishitani H, et. al.
- Journal Title
  
  EMBO J. 25
  
  Pages: 1126-1136
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570181
[Journal Article] Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.2004
- Author(s)
  Sugimoto N, Tatsumi Y, Tsurumi T, Matsukage A, Kiyono T, Nishitani H, Fujita M.
- Journal Title
  
  J. B i o l. C h e m. 279
  
  Pages: 19691-19697
- Data Source
  KAKENHI-PROJECT-17080013
[Journal Article] Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of Geminin through its N-terminal region2004
- Author(s)
  Nishitani H. et al.
- Journal Title
  
  J Biol.Chem. 279
  
  Pages: 30807-30816
- Data Source
  KAKENHI-PROJECT-16026233
[Journal Article] Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region2004
- Author(s)
  H.Nishitani et al.
- Journal Title
  
  J.Biol.Chem 279
  
  Pages: 30807-30816
- Data Source
  KAKENHI-PROJECT-12002011
[Journal Article] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis
- Author(s)
  Nishitani H. et al.
- Journal Title
  
  EMBO J (in press)
- Data Source
  KAKENHI-PROJECT-16026233
[Presentation] DNA再複製に伴う細胞内Ca2+濃度変化の解析2022
- Author(s)
  飯田康介　渡邉雄一郎　林晃世　塩見泰史　西谷秀男
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] 新規PCNA除去機構におけるTRAIPの機能解析2022
- Author(s)
  田所あすか　西谷秀男　塩見泰史
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] クロマチンからのPCNA除去に連係したDNA複製制御2022
- Author(s)
  塩見泰史　田所あすか　鐘巻将人　西谷秀男
- Organizer
  第４５回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] DNA損傷修復において機能するCRL4-Cdt2ユビキチンリガーゼの損傷部位集積機構の解析2021
- Author(s)
  海老原渓、日下部将之、林晃世、塩見泰史、菅澤薫、西谷秀男
- Organizer
  第38回染色体ワークショップ・第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] NEDD8 化阻害により誘導されるDNA 再複製の機構2021
- Author(s)
  渡邊雄一郎、林晃世、塩見泰史、西谷秀男
- Organizer
  第26 回DNA 複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] ゲノム安定性維持に関わるCRL4Cdt2 ユビキチンリガーゼの損傷部位集積機構の解析2021
- Author(s)
  海老原渓、日下部将之、林晃世、塩見泰史、菅澤薫、西谷秀男
- Organizer
  第26 回DNA 複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] CRL4-Cdt2 ubiquitin ligase, a critival factor to block re-replication of chromosomal DNA and its implication as a target for anti-cancer drug development2021
- Author(s)
  Hideo Nishitani
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] DNA損傷修復において機能するCRL4Cdt2ユビキチンリガーゼの損傷部位集積機構のライブイメージ解析2021
- Author(s)
  海老原渓、日下部将之、林晃世、塩見泰史、菅澤薫、西谷秀男
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] DNA再複製誘導による過剰な複製の開始タイミングの解析2020
- Author(s)
  渡邊雄一郎、林晃世、高原教代、塩見泰史、西谷秀男
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06547
[Presentation] RFC 複合体によるDNAへのPCNA着脱と連係した細胞内機能の解析2017
- Author(s)
  塩見泰史、織田里美、佐藤護、夏目豊彰、鐘巻将人、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] Cdt2-PCNA融合体は CRL4Cdt2の抑制制御を損なう2017
- Author(s)
  荻野寛行、植田麻紗子、林晃世、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] 紫外線照射による G1期 CRL4Cdt2の活性化におけるミスマッチ修復系の関与2017
- Author(s)
  高原教代、田中美如、貫名康平、林晃世、酒井恒、菅澤薫、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] DNA複製ライセンス化因子 Cdt1の M期における機能の解析2017
- Author(s)
  羽多野達也、前田武志、村上裕輔、林晃世、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] ゲノム維持に関わる E3ユビキチンリガーゼ CRL4-Cdt2の基質認識サブユニット Cdt2のリン酸化による制御の解析2017
- Author(s)
  貫名康平、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] 転写因子 E2F1の N末端領域に対する新規相互作用因子 WDR1の機能解析2017
- Author(s)
  根岸泰明、荒木啓吾、西谷秀男、大谷清
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2はPCNAと直接結合して機能する2017
- Author(s)
  林晃世、石井健士、末永尚弘、高原教代、塩見泰史、西谷秀男
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] DDB2依存的なHBO1のリクルートはヌクレオチド除去修復に必須である2016
- Author(s)
  丹伊田浩行、松沼亮一、堀口涼、内田千晴、酒井聡、大畑樹也、北川恭子、森脇真一、西谷秀男、宇井彩子、荻朋男、北川雅俊
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] DNA複製ライセンス化因子Cdt1はM期にリン酸化され、分解から保護される2016
- Author(s)
  北詰麻衣、熊田ちひろ、村上裕輔、前田武志、塩見泰史、西谷秀男
- Organizer
  ３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26650064
[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2のピPボックスの役割＿細胞での解析2016
- Author(s)
  高原教代、末永尚弘、石井健士、林晃世、塩見泰史、西谷秀男
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] Direct binding between PCNA and E3 ligase CRL4Cdt2 supports substrate targeting, and subsequent proteolysis during DNA replication.2016
- Author(s)
  Akiyo Hayashi, Naohiro Suenaga, Michiyo Takahara, Takashi Ishii, Yasushi Shiomi, Hideo Nishitani
- Organizer
  10th 3R International Synposium
- Place of Presentation
  Matsue, Japan
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] E3ユビキチンリガーゼCRL4Cdt2の基質認識サブユニットCdt2のリン酸化による制御の解析2016
- Author(s)
  貫名康平、塩見泰史、西谷秀男
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] ゲノム複製を制御するユビキチンリガーゼCRL4-Cdt2のPIPボックスの役割＿試験管内解析2016
- Author(s)
  林晃世、高原教代、末永尚弘、石井健士、高橋達郎、塩見泰史、西谷秀男
- Organizer
  第３９回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] PCNAアンローダー、Elg1-RFCの細胞内および生化的機能の解析2015
- Author(s)
  塩見泰史、西谷秀男
- Organizer
  第３８回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　（兵庫県）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] In vitro analysis of DNA-bound PCNA dependent ubiquitin ligase CRL4-Cdt22015
- Author(s)
  Akiyo Hayashi, Yasushi Shiomi, Tatsuro S. Takahashi, Hideo Nishitani
- Organizer
  Cold Spring Harbor Laboratory Meeting “Eukaryotic DNA replication and genome maintenance”
- Place of Presentation
  Cold Spring Harbor Laboratory (New York, USA)
- Year and Date
  2015-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] DNA複製ライセンス化因子Cdt1のリン酸化によるM期安定化機構の解析2015
- Author(s)
  北詰麻衣、熊田-岸ちひろ、村上裕輔、前田武志、塩見泰史、西谷秀男
- Organizer
  第３８回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　（兵庫県）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26650064
[Presentation] ゲノム維持に関わる酵素CRL4-Cdt2の機能解析2013
- Author(s)
  末永尚弘，石井健士，塩見泰史，西谷秀男
- Organizer
  第３６回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　（兵庫県）
- Data Source
  KAKENHI-PUBLICLY-25131718
[Presentation] クロマチンで機能するPCNA の制御を介したDNA 複製とゲノムintegrity の維持2013
- Author(s)
  塩見泰史，西谷秀男
- Organizer
  第３６回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　（兵庫県）
- Data Source
  KAKENHI-PUBLICLY-25131718
[Presentation] UV 照射時におけるDNA 修復過程と共役したCdt1分解2013
- Author(s)
  田中美如，石井健士，塩見泰史，西谷秀男
- Organizer
  第３６回　日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　（兵庫県）
- Data Source
  KAKENHI-PUBLICLY-25131718
[Presentation] Regulation of replication-coupled proteolysis of licensing factor Cdt1 by ubiquitin ligase CRL4-Cdt22012
- Author(s)
  Takashi Ishii, Yasushi Shiomi, and Hideo Nishitani
- Organizer
  The 8 th 3R Symposium
- Place of Presentation
  Awaji Yumebutai International Conference Center（兵庫県）
- Year and Date
  2012-11-25
- Data Source
  KAKENHI-PUBLICLY-23131512
[Presentation] ユビキチンリガーゼCRL4-Cdt2によるPCNA依存的なユビキチン化機構の解析2012
- Author(s)
  林晃世, 塩見泰史, 西谷秀男
- Organizer
  第３５回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡　（福岡県）
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23131512
[Presentation] Novel function of RFC complexes in genome stability through PCNA-CRL4Cdt2 mediated Cdt1 degradation during DNA replication and repair2012
- Author(s)
  塩見泰史, 林晃世, 石井健士, 中山潤一,菅澤薫, 塩見泰史, 西谷秀男
- Organizer
  第３５回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡　（福岡県）
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23131512
[Presentation] M期のUV損傷に応答したCdt1分解によるG1-DNA損傷チェックポイント2012
- Author(s)
  森野公之, 塩見泰史, 西谷秀男
- Organizer
  第３５回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡　（福岡県）
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23131512
[Presentation] CRL4-Cdt2によるCdt1のユビキチン化はそれぞれのPIPボックスを介したPCNA結合に依存する2012
- Author(s)
  石井健士, 林晃世, 末永尚弘, 中島秀祐, 塩見泰史, 西谷秀男
- Organizer
  第３５回　日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡　（福岡県）
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23131512
[Presentation] DNA複製時に機能するCRL4-Cdt2によるユビキチン化反応のin vitro再構成とその活性制御機構の解析2011
- Author(s)
  林晃世、末永尚弘、塩見泰史、西谷秀男
- Organizer
  第21回DNA複製・組換え・ゲノム安定性制御ワークショップ
- Place of Presentation
  福岡
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] CRL4Cdt2によるCdt1のユビキチン化はCdt2のPCNAへの結合を必要とする2011
- Author(s)
  石井健士、塩見泰史、西谷秀男
- Organizer
  34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] New function of PCNA loaders, RFC1-RFC and Ctf18-RFC, in genome stability through PCNA-CRL4Cdt2 mediated Cdt1 degradation2011
- Author(s)
  Yasushi Shiomi, Akiyo Hayashi, Naohiro Suenaga, Miyuki Tanaka, Jun-ichi Nakayama, Kaoru Sugasawa, Hideo Nishitani
- Organizer
  34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] M期のDNA損傷に応答したCdt1分解による新規のDNA損傷チェックポイントの可能性2011
- Author(s)
  森野公之、塩見泰史、西谷秀男
- Organizer
  第21回DNA複製・組換え・ゲノム安定性制御ワークショップ
- Place of Presentation
  福岡
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] DNA損傷時におけるユビキチンリガーゼCRL4Cdt2の活性化制御機構2011
- Author(s)
  坂口洋貴、安谷賢識、林晃世、塩見泰史、西谷秀男
- Organizer
  34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] M期キナーゼPlk1はCdk1-CyclinBとともにライセンス化因子Cdt1をリン酸化してM期に分解から守る2011
- Author(s)
  村上祐輔、前田武志、岸ちひろ、松本雅記、中山敬一、塩見泰史、西谷秀男
- Organizer
  34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] Plk1によるDNA複製ライセンス化因子Cdt1のM期安定化機構の解析2011
- Author(s)
  前田武志、村上祐輔、塩見泰史、西谷秀男
- Organizer
  第21回DNA複製・組換え・ゲノム安定性制御ワークショップ
- Place of Presentation
  福岡
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] PCNA-CRL4Cdt2によるライセンス化因子Cdt1のユビキチン化機構の解析2011
- Author(s)
  石井健士、塩見泰史、西谷秀男
- Organizer
  第21回DNA複製・組換え・ゲノム安定性制御ワークショップ
- Place of Presentation
  福岡
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 複製と損傷に応答して機能するユビキチンリガーゼCRL4-Cdt2の制御機構2010
- Author(s)
  塩見泰史・西良太郎・菅澤薫・中山潤一・西谷秀男
- Organizer
  33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] Cdt1のM期安定化分子機構の解析2010
- Author(s)
  村上裕輔・岸ちひろ・松本雅記・中山敬一・塩見泰史・西谷秀男
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] DNA損傷時におけるユビキチンリガーゼCRL4-Cdt2の活性化制御機構2010
- Author(s)
  坂口洋貴、西谷秀男, 他3名
- Organizer
  第3回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] Cdt1 and CRL4/Cdt2 were recruited rapidly to UV-induced DNA damage site dependent on PCNA-binding2010
- Author(s)
  Ishii T, Shiomi Y, Murakami Y, Nishitani H
- Organizer
  The 7th 3R(Replication, Recombination and Repair) Symposium
- Place of Presentation
  Toyama
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] ライセンス化因子Cdt1はPCNA依存的にDNA損傷部位に集積し分解される2010
- Author(s)
  石井健士、塩見泰史、西谷秀男
- Organizer
  第3回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] ライセンス化因子Cdt1はPCNA依存的にDNA損傷部位に集積し分解される2010
- Author(s)
  石井健士・塩見泰史・西谷秀男
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] DNA損傷時におけるユビキチンリガーゼCRL4Cdt2の活性化制御機構2010
- Author(s)
  坂口洋貴・安谷賢識・高見俊宏・塩見泰史・西谷秀男
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 複製因子PCNAに依存したユビキチン化システムによる染色体維持機構2009
- Author(s)
  西谷秀男, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 複製因子PCNAに依存したユビキチン化システムによる染色体維持機能2009
- Author(s)
  塩見泰史、石井健士、道下雅人、高見俊宏、大西奈保、西谷秀男
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 細胞周期進行制御因子Cdt2の解析2009
- Author(s)
  高見俊宏、塩見泰史、西谷秀男
- Organizer
  第20回DNA複製・組換え・修復ワークショップ
- Place of Presentation
  滋賀県彦根市
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] DNA損傷部位へのCul4/DDB1/Cdt2複合体の基質認識サブユニットCdt2の局在化2009
- Author(s)
  石井健士、塩見泰史、大西奈保、西谷秀男
- Organizer
  31回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 複製因子PCNAに依存したユビキチン化システムによる染色体維持機構2009
- Author(s)
  西谷秀男, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20058030
[Presentation] 紫外線に応答したヒトCul4-DDB1Cdt2による細胞周期連携因子のユビキチン化と分解機構2009
- Author(s)
  塩見泰史、石井健士、中山潤一、西谷秀男
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 複製因子PCNAに依存したユビキチン化システムによる染色体維持機構2009
- Author(s)
  西谷秀男, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20012047
[Presentation] 紫外線に応答したヒトCul4-DDB1^<Cdt2>によるCdt1のユビキチン化と分解機構2009
- Author(s)
  塩見泰史、西谷秀男
- Organizer
  第20回DNA複製・組換え・修復ワークショップ
- Place of Presentation
  滋賀県彦根市
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] 染色体複製制御因子Cul4-DDB1-Cdt2ユビキチンリガーゼによる基質認識機構の解析2009
- Author(s)
  道下雅人、塩見泰史、西谷秀男
- Organizer
  第20回DNA複製・組換え・修復ワークショップ
- Place of Presentation
  滋賀県彦根市
- Year and Date
  2009-11-02
- Data Source
  KAKENHI-PROJECT-21370081
[Presentation] Proteolysis of Licensing Factor Cdt1 and its role on DNA replication2007
- Author(s)
  Nishitani H, Shiomi Y, Iida H, Lygerou, Z
- Organizer
  BMB
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Presentation] ライセンス化因子Cdt1の分解機構と染色体複製の制御2007
- Author(s)
  西谷秀男, 他
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19044031
[Presentation] ライセンス化因子Cdt1の分解機構と染色体複製の制御2007
- Author(s)
  西谷秀男, 他
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Presentation] Tsurimoto, TControl on the DNA replication Licensing factor Cdt12006
- Author(s)
  Nishitani H, Iida H, Sugimoto N, Fujita M, Lygerou Z
- Organizer
  MBSJ Forum
- Place of Presentation
  Nagoya
- Year and Date
  2006-12-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Presentation] Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdtl for proteolysis2006
- Author(s)
  Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Fujit M, Lygerou Z, Nishimoto T
- Organizer
  IUBMB
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Presentation] 染色体複製のライセンス化因子Cdt1の制御機構の解析2006
- Author(s)
  西谷秀男, 他
- Organizer
  日本分子生物学会
- Place of Presentation
  名古屋
- Year and Date
  2006-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Presentation] Two ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdtl for proteolysis2006
- Author(s)
  西谷秀男, 他
- Organizer
  20th IUBMB
- Place of Presentation
  京都
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570181
[Presentation] Mechanism of replication-coupled destruction of DNA replication licensing factor, Cdt1 by a CRL4-Cdt2 ubiquitin ligase
- Author(s)
  Naohiro Suenaga, Takashi Ishii, Akiyo Hayashi, Yasushi Shiomi, Hideo Nishitani
- Organizer
  2nd International Picobiology Institute Symposium
- Place of Presentation
  Center for Advanced Science & Technology (Hyogo), Japan
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PUBLICLY-25131718
[Presentation] PCNAアンローダー、Elg1-RFCの機能解析
- Author(s)
  塩見泰史　西谷秀男
- Organizer
  第３７回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] 紫外線DNA損傷時におけるCdt1分解の解析
- Author(s)
  田中美如、高原教代、塩見泰史、西谷秀男
- Organizer
  第３７回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25131718
[Presentation] Mechanism of replication-coupled destruction of DNA replication licensing factor, Cdt1 by a CRL4-Cdt2 ubiquitin ligase
- Author(s)
  Naohiro Suenaga, Takashi Ishii, Akiyo Hayashi, Yasushi Shiomi, Hideo Nishitani
- Organizer
  2nd International Picobiology Institute Symposium “Development and Destruction
- Place of Presentation
  Center for Advanced Science & Technology (Hyogo) Japan
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] DNA修復とエピゲノム制御に関わるチミンDNAグリコシラーゼの機能制御
- Author(s)
  中村知史、村上浩一、上原芳彦、小野哲也、浦野健、西谷秀男、菅澤薫
- Organizer
  DNA修復とエピゲノム制御に関わるチミンDNAグリコシラーゼの機能制御
- Place of Presentation
  パシフィコ横浜　（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] S期クロマチン特異的なタンパク質分解系CRL4-Cdt2の制御機構
- Author(s)
  林晃世、塩見泰史高橋達郎末永尚弘西谷秀男
- Organizer
  第３７回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25131718
[Presentation] Mechanism of replication-coupled destruction of DNA replication licensing factor, Cdt1 by a CRL4-Cdt2 ubiquitin ligase
- Author(s)
  Naohiro Suenaga, Takashi Ishii, Akiyo Hayashi, Yasushi Shiomi, Hideo Nishitani
- Organizer
  2nd International Picobiology Institute Symposium “Development and Destruction”
- Place of Presentation
  Center for Advanced Science & Technology (Hyogo) Japan
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26650064
[Presentation] S期クロマチン特異的なタンパク質分解系CRL4-Cdt2の制御機構
- Author(s)
  林晃世、塩見泰史高橋達郎末永尚弘西谷秀男
- Organizer
  第３７回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291025
[Presentation] DNA修復とエピゲノム制御に関わるチミンDNAグリコシラーゼの機能制御
- Author(s)
  中村知史、村上浩一、上原芳彦、小野哲也、浦野健、西谷秀男、菅澤薫
- Organizer
  第３７回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-25131718

1. SHIOMI Yasushi (80380567)

# of Collaborated Projects: 6 results

# of Collaborated Products: 46 results
2. NISHIMOTO Takeharu (10037426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HAYASHI Akiyo (20779350)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. FUJITA Masatoshi (30270713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MIZUNO Takeshi (30281629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AZUMA Yoshiaki (40294954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HAYASHI Naoyuki (50253456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKIHARA Yoshihiro (60226967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OHTSUBO Motoaki (10211799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YASUNAGA Shin'ichiro (50336111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKIHARA Keiko (70252640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIROSE Eiji (40380620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. INAI Tetsuichiro (00264044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIBATA Yosaburo (90037482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 関口猛 (60187846)

# of Collaborated Projects: 1 results

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16. OHBA Tomoyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NOGUCHI Eishi

# of Collaborated Projects: 1 results

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18. 西嶋仁

# of Collaborated Projects: 1 results

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19. 沖昌也

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NISHI Ryotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. HAYASHI Aki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 中山潤一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishitani Hideo 西谷 秀男

NISITANI Hidbo 西谷 秀男

Research Projects

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Mechanism of DNA synthesis-activated proteolysis for genome integrityPrincipal Investigator

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Regulation of DNA replication through proteolysis coupled with PCNA cyclePrincipal Investigator

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Coupling of spindle checkpoint with initiation of DNA replicationPrincipal Investigator

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修復と複製時に機能するCul4-DDB1-Cdt2によるゲノム維持機構Principal Investigator

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Ｍ期ＤＮＡ損傷の修復系とＤＮＡ複製開始制御の連係機構の解析Principal Investigator

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タンパク質分解系による複製のライセンシング確立の制御機構Principal Investigator

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Regulation of genome integrity through a DNA replication coupled feedback controlPrincipal Investigator

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UV照射後に活性化されるCul4-DDB1-Cdt2によるCdt1分解機構の解析Principal Investigator

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タンパク質分解による複製のライセンス化制御Principal Investigator

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DNA複製と連係したタンパク質分解機構の解明(p21Cip1を中心に)Principal Investigator

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Study on the novel S-phase specific proteolysis pathwayPrincipal Investigator

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Molecular anatomical research of nuclear membrane in mitotic phase : the ultra structure of the surface and genes regulate it.

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Molecular mechanisms for pre-replication complexes assembly and its implication in chromosomal stability in mammalian cells

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Nishitani Hideo 西谷秀男

NISITANI Hidbo 西谷秀男

[Book] タンパク質分解系による染色体の再複製抑制機構実験医学(増刊)　細胞周期2013