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HONDA Shinichiro  本田 伸一郎

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HONDA Shin-ichiro  本田 伸一郎

HONDA Shin-ichiroh  本田 伸一郎

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Researcher Number 40257639
Other IDs
External Links
Affiliation (Current) 2025: 福岡大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 福岡大学, 薬学部, 教授
2017: 福岡大学, 薬学部, 教授
2011 – 2016: 福岡大学, 薬学部, 准教授
2009: Fujita Health University, 薬学部, 准教授
2007 – 2008: Fujita Health University, 医学部, 准教授 … More
2000 – 2005: 藤田保健衛生大学, 医学部, 講師
1998 – 1999: 藤田保健衛生大学, 医学部, 助手
1994 – 1997: 藤田保健衛生大学, 総合医科学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Endocrinology / Endocrinology / Functional biochemistry / Basic Section 54040:Metabolism and endocrinology-related
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Endocrinology / Biological Sciences / Endocrinology / Embryonic/Neonatal medicine / Metabolomics
Keywords
Principal Investigator
ステロイドホルモン / 性分化 / 遺伝子発現 / アロマターゼ / エストロゲン / 転写制御 / 中枢神経系 / 転写因子 / 脳 / トランスジェニックマウス … More / 核内受容体 / 脳の性分化 / アロマターゼ遺伝子 / 転写調節因子 / 神経細胞 / 転写調節 / 中枢神経 / チトクロームP450 / チトクロームP-450 / 骨密度 / ノックアウトマウス … More
Except Principal Investigator
アロマターゼ / エストロゲン / Cyp1B1 / トランスジェニックマウス / ノックアウトマウス / ステロイドサルファターゼ / Aromatase / 組織特異的発現 / aromatase / 乳癌 / 女性医学 / 食欲 / ニューロエストロゲン / Estrogen sulfotransferase / Steroid sulfatase / Estrogen / Knockout mouse / Transgenic mouse / エストロン硫酸転移酵素 / エストロゲン硫酸抱合化酵素 / aromatase knockout mice / breast cancer / fluorescent probe / estrogen sulfotransferase / CVP IB 1 / steroid sulfatase / estrogen / SNP / 発癌感受性 / 17β-水酸化ステロイド脱水素酵素 / ホルモン療法 / 炎症性サイトカイン / OAT-3 / siRNA / GFP / ナロマターゼ / 細胞間相互作用 / エストロゲン依存性癌 / アロマターゼ欠損マウス / 蛍光プローブ / エストロゲン硫酸転移酵素 / cyp1B1 / Multiple promoters / Tissue-specific expression / Sexual differentiation of the brain / trasgenic mouse / knockout mouse / 組織特異的転写因子 / 骨粗鬆症 / 多重プロモーター / 脳の性分化 / placenta / trophoblast / transcription factor / シスエレメント / プロモーター / hCG / 栄養胚芽細胞 / 栄養胚葉細胞 / 胎盤 / 転写因子 / ホルモン依存性腫瘍 Less
  • Research Projects

    (16 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (12 People)
  •  遺伝子改変動物を用いたMetallophosphodiesteraseの生理機能の解析Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Fukuoka University
  •  遺伝子改変マウスを用いたニューロエストロゲンが摂食行動に与える影響

    • Principal Investigator
      西尾 永司
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Fujita Health University
  •  Analysis of protein regulating brain-specific aromatase gene expression through proteomicsPrincipal Investigator

    • Principal Investigator
      Honda Shin-ichiro
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Fukuoka University
  •  Functional analysis of transcription factors regulating brain-spesific expression of aromatase genePrincipal Investigator

    • Principal Investigator
      HONDA Shin-ichiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Fukuoka University
  •  Analysis of the expression of the brain-specific aromatase gene for the sexual dimorphic nucleus in the brainPrincipal Investigator

    • Principal Investigator
      HONDA Shinichiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Fujita Health University
  •  Endocrinological analysis of genetically modified mice with abnormal estrogen metablism

    • Principal Investigator
      HARADA Nobuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Fujita Health University
  •  エストロゲン依存性癌におけるエストロゲン生合成と代謝に関する研究

    • Principal Investigator
      坂本 秀生
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Fujita Health University
  •  発生工学的手法を用いた脳内アロマターゼの機能に関する研究Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Endocrinology
    • Research Institution
      Fujita Health University
  •  発生工学的手法を用いたアロマターゼの機能と発現調節に関する研究Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Endocrinology
    • Research Institution
      Fujita Health University
  •  Study on the protection against estrogen-dependent cancer

    • Principal Investigator
      HARADA Nobuhiro
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      藤田保健衛生大学
  •  Analysis of aromatase/estrogen system in the age-related diseases by developmental engineering techniques

    • Principal Investigator
      HARADA Nobuhiro
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      Fujita Health University
  •  遺伝子破壊マウスを用いたアロマターゼの生理機能に関する研究Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Endocrinology
    • Research Institution
      Fujita Health University
  •  中枢神経系の性分化におけるアロマターゼの機能に関する研究Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Fujita Health University
  •  Studies on the gene expression involved in the placetal development.

    • Principal Investigator
      YAMADA Kazuyo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Fujita Health University
  •  中枢神経系の性分化におけるアロマターゼの機能に関する分子遺伝学的研究Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Fujita Health University
  •  脳の性分化におけるアロマターゼの機能に関する分子遺伝学的研究Principal Investigator

    • Principal Investigator
      本田 伸一郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Fujita Health University

All 2017 2016 2015 2014 2012 2011 2009 2008 2007 2001

All Journal Article Presentation Book

  • [Book] Molecular Mechanisms Controlling Brain Aromatase Expression. BRAIN AROMATASE ESTROGENS AND BEHAVIOR(Chapter 8)2012

    • Author(s)
      Harada, N. and Honda, S.
    • Publisher
      OXFORD UNIVERSITY PRESS(ISBN : 978-0-19-84119-6)
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Journal Article] Aromatase knockout mice reveal an impact of estrogen on drug-induced alternation of murine electrocardiography parameters2015

    • Author(s)
      Kurokawa, J., Sasano, T., Kodama, M., Li, M., Ebana, Y., Harada, N., Honda, S., Nakaya, H., Furukawa, T
    • Journal Title

      J. Toxicol. Sci.

      Volume: 40 Pages: 339-348

    • NAID

      130005068413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Journal Article] LIM-homeo domain transcription factor, Lhx2, is involved in transcriptional control of brain-specific promoter/exon 1f of the2012

    • Author(s)
      Honda, S.-I., Kozako, T., Shimeno, H.
    • Journal Title

      J Neuro

      Volume: 66(2) Issue: 11 Pages: 260-272

    • DOI

      10.1111/j.1365-2826.2012.02356.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591019, KAKENHI-PROJECT-23591360, KAKENHI-PROJECT-24591413
  • [Journal Article] Behavioral analysis of genetically modified mice indicates essential roles of neuro- steroidal estrogen2011

    • Author(s)
      Honda, S-I., Wakatsuki, T., & Harada, N.
    • Journal Title

      Frontiers in Endocrinology

      Volume: Vol.2, article 40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Journal Article] Behavioral analysis of genetically modified mice indicates essential roles2011

    • Author(s)
      Honda S-I, Wakatsuki T, Harada
    • Journal Title

      Front

      Volume: 2 Pages: 40-40

    • DOI

      10.3389/fendo.2011.00040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591019, KAKENHI-PROJECT-23580388, KAKENHI-PROJECT-23591360
  • [Journal Article] Functional analysis of neurosteroidal oestrogen using gene-disrupted and transgenic mice.2009

    • Author(s)
      Harada N., Wakatsuki T., Aste N., Yoshimura N., Honda S.
    • Journal Title

      J. Neuroendocrinol 21

      Pages: 365-369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Journal Article] Estrogen masculinizes neural pathways and sex-specific behaviors.2009

    • Author(s)
      Wu, M.V., Manoli, D.S., Fraser, E.J., Coats, J.K., Tollkuhn, J., Honda, S., Harada, N., Shah, N.M.
    • Journal Title

      Cell 139

      Pages: 61-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Journal Article] Regulation of progestin receptors in medial amygdala: estradiol, phytoestrogens and sex.2009

    • Author(s)
      Kudawa A.E., Harada N., Honda S-I., Rissman E.F.
    • Journal Title

      Physiol. Behav. 97

      Pages: 146-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Journal Article] Acute effects of estrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization2008

    • Author(s)
      Kurokawa J., Tamagawa M, Harada N., Honda S, I., Bai C, X,, Nakaya H., Furukawa T
    • Journal Title

      J. Physiol Vol.586(12)

      Pages: 2961-2973

    • Data Source
      KAKENHI-PROJECT-19591086
  • [Journal Article] Loss of aromatase cytochrome P450 function as a risk factor for Parkinson's disease?2008

    • Author(s)
      Morale M.C., L'Episcopo F., Tirolo C., Giaquinta G., Caniglia S., Testa N., Arcieri P., Serra P.A., Lupo G., Alberghina M., Harada N., Honda S., Panzica G.C., Marchetti B.
    • Journal Title

      Brain Res. Rev. Vol.57(2)

      Pages: 431-443

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Journal Article] Effects of organisational oestradiol on adult immunoreactive oestrogen receptors (alpha and beta) in the male mouse brain2007

    • Author(s)
      Kudwa A.E., Harada N., Honda S., Rissman E.F.
    • Journal Title

      J. Neuroendocrinol Vol.19(10)

      Pages: 767-772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Journal Article] Analysis of transcriptional regulation of human breast aromatase by in vitro and in vivo studies.2001

    • Author(s)
      Harada N, Matsumoto T, Yoshimura N, Sakamoto H, Honda S.
    • Journal Title

      J. Steroid Biochem. Mol. Biol. 79

      Pages: 151-156

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213132
  • [Presentation] アロマターゼの脳特異的プロモーターに結合するタンパク質の単離・解析2017

    • Author(s)
      本田伸一郎
    • Organizer
      内外環境応答・代謝酵素研究会プログラム
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] ARP1と相互作用するタンパク質の解析2017

    • Author(s)
      本田伸一郎、小迫知弘、相川晃慶、原田信広
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] アロマターゼ遺伝子の脳特異的プロモーター活性を制御するタンパク質の解析2016

    • Author(s)
      本田伸一郎、原田信広、小迫知弘、坂田晃、相川晃慶、刀根菜七子、添田秦司
    • Organizer
      日本薬学会第136回
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] 核内レセプターによるアロマターゼ遺伝子の転写制御2015

    • Author(s)
      本田伸一郎、小迫知弘、相川晃慶、坂田晃、刀根菜七子、原田信広、添田秦司
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] Deaf1タンパク質の機能ドメインの解析2014

    • Author(s)
      本田伸一郎、原田信広、小迫知弘、相川晃慶、坂田晃、添田秦司
    • Organizer
      日本薬学会第134回年会
    • Place of Presentation
      熊本市
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] アロマターゼの脳特異的プロモーターに存在するシスエレメント、AIIサイトに結合する転写因子の解析2014

    • Author(s)
      山口貴広、本田伸一郎、小迫知弘、相川晃慶、坂田晃、原田信広、添田秦司
    • Organizer
      2014年日本薬学会九州支部会
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-07
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] 脳内アロマターゼの機能と発現制御2014

    • Author(s)
      本田伸一郎
    • Organizer
      第3回 福岡病態・代謝研究会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-24
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] Deaf1タンパク質の機能ドメインの解析2014

    • Author(s)
      本田伸一郎、原田信広、小迫知弘、相川晃慶、坂田晃、添田秦司
    • Organizer
      第134回日本薬学会年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-30
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] 脳特異的アロマターゼプロモーターの活性に及すDeaf1のSUMO化の影響2014

    • Author(s)
      本田伸一郎、小迫知弘、相川晃慶、坂田晃、原田信広、添田秦司
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-26461389
  • [Presentation] アロマターゼの脳特異的発現に関与する転写因子Deaf-1の機能ドメインの解析2012

    • Author(s)
      本田伸一郎、大下遥子、民本愛、小迫知弘、蔵元佑嘉子、元流梨恵、原田信広、添田秦司
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] アロマターゼの脳特異的発現に関与する転写因子Deaf-1の機能ドメインの解析2012

    • Author(s)
      本田伸一郎、大下遥子、民本愛、小迫知弘、蔵元佑嘉子、元流梨恵、原田信広、添田秦司
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-16
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] 脳特異的なアロマターゼ発現に関与するDeaf-1タンパク質の機能解析2011

    • Author(s)
      原口美紀、古田展也、安田千穂、本田伸一郎、小迫知弘、蔵元佑嘉子、元流梨恵、原田信広、占野廣司、添田秦司
    • Organizer
      日本生化学会九州支部例会
    • Place of Presentation
      久留米
    • Year and Date
      2011-05-22
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] アロマターゼの脳特異的プロモーター結合因子の解析2011

    • Author(s)
      大下遥子、本田伸一郎、小迫知弘、蔵元佑嘉子、元流梨恵、原田信広、添田秦司、占野廣司
    • Organizer
      第39回薬物活性シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] 発生工学的手法を用いた脳内アロマターゼの機能解析2011

    • Author(s)
      民本愛、本田伸一郎、小迫知弘、蔵元佑嘉子、元流梨恵、原田信広、添田秦司、占野廣司
    • Organizer
      第39回薬物活性シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-23591360
  • [Presentation] Analysis of functional domain of Deaf1 protein for the activation of the brain-specific aromatase gene expression2009

    • Author(s)
      本田伸一郎
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜市・パシフィコ横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Presentation] Analysis of functional domain of Deaf1 protein for the activation of the brain-specific aromatase gene expression2009

    • Author(s)
      本田伸一郎
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Presentation] Multiple transcription factors regulate the brain-specific promoter activity of the aromatase gene2008

    • Author(s)
      本田伸一郎
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Presentation] Multiple transcription factors regulate the brain-specific promoter activity of the aromatase gene2008

    • Author(s)
      本田伸一郎
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Presentation] アロマターゼ脳特異的プロモーターに作用する転写因子DEAF-1、およびUbc9の作用2007

    • Author(s)
      本田 伸一郎
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19591086
  • [Presentation] アロマターゼ脳特異的プロモーターに作用する転写因子DEAF-12007

    • Author(s)
      本田伸一郎
    • Organizer
      およびUbc9の作用第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19591086
  • 1.  HARADA Nobuhiro (00189705)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 2.  SASAKI Emi (20178635)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  UTSUMI Toshiaki (10176711)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YAMADA Kazuyo (90080217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MOROHASHI Ken-ichiro (30183114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SASANO Hironobu (50187142)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HAYASHI Shin-ichi (60144862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  坂本 秀生 (30225817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  西尾 永司 (80367705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  熊本 海生航 (10469322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  林 孝典 (40724315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  下野 洋平 (90594630)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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