Ogasawara Sachiko 小笠原幸子

… Alternative Names

小笠原幸子オガサワラサチコ

OGASAWARA Sachiko 小笠原幸子

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Researcher Number	40258405
Affiliation (Current)	2025: 久留米大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 久留米大学, 医学部, 准教授 2018 – 2021: 久留米大学, 医学部, 講師 2007 – 2009: 久留米大学, 医学部, 講師 1997 – 2003: 久留米大学, 医学部, 助手
Review Section/Research Field	Except Principal Investigator Experimental pathology / Basic Section 49020:Human pathology-related / Experimental pathology
Keywords	Except Principal Investigator 肝細胞癌 / Cell line / 細胞株 / Hepatocellular carcinoma / 免疫染色 / マイクロアレイ / Interferon-α subtypes / 5-Fu / Nude mouse / Caspase … More / Apoptosis / Interferon-α / matrigel / 肝癌 / CD9 / ヌードマウス / アポトーシス / マイクロダイセクション / 門脈侵襲 / バイオマーカー / 門脈浸潤 / 網羅的解析 / 細胆管型 / FFPE / 肝ステム像 / 組織診断 / HepPar-1 / ケラチン19 / ケラチン7 / 診断マーカー / 網羅的遺伝子解析 / 中間細胞亜型 / 胆管細胞癌 / 遺伝子発現 / 組織診断マーカー / 中間細胞型 / 混合型肝癌 / 増殖抑制 / インターフェロン-αサブタイプ / Western blotting / RT-PCR / cytochrome c / カスペース(caspase) / 抗癌剤 / 血管新生 / コンセンサスインターフェロン / インターフェロン-α / Hepatocellular carsinoma / membrane-typematrix metalloproteinase / chemotaxis / chemokinesis / tissue inhibitor of metalloproteinase / matrix metalloproteinase / 金コロイド / 肝細胞増殖因子 / enzyme-linkedimmunosorbentassay / フローサイトメトリー / 免疫組織化学 / Membrane-type matrix metalloproteinase / Membrane-typematrix metalloproteinase / ケモカイネシス / ケモタキシス / Matrix metalloproteinase / Tissue inhibitor of metalloproteinase / Immunohistochemistry / Paracrine mechanism / Autocrine mechanism / Epidermal growth factor family / Heparin binding-growth factor-like growth factor / ジャクスタクライン / ヘパリン / 上皮細胞増殖因子ファミリーオートクライン / パラクライン / オートクライン / 上皮細胞増殖因子ファミリー / ヘパリン結合性上皮細胞増殖因子様増殖因子 / TRAIL receptor / TRAIL / Cox-2阻害剤 / p21 / 細胞周期 / NFκB阻害剤 / チロシンキナーゼ阻害剤 / ベバシズマブ / 血管内皮細胞増殖因子 / 分子標的薬剤 / 阻害剤 / インターフェロン / サイトカイン / 腫瘍 Less

Identification of key molecules controlling portal vein invasion of hepatocellular carcinoma
- Principal Investigator
  
  Yano Hirohisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kurume University
Identification of diagnostic marker of combined hepatocellular-cholangiocarcinoma subtypes by gene expression analysis
- Principal Investigator
  
  YANO Hirohisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kurume University
Basic studies on the treatment and prevention of hepatocellular carcinoma with interferon
- Principal Investigator
  
  YANO Hirohisa
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kurume University
Basic research on anti-tumor effects of Interferon-α on hepatocellular carcinoma
- Principal Investigator
  
  YANO Hirohisa
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  KURUME UNIVERSITY
STUDIES ON THE EXPRESSION OF FACTORS RELATED WITH INVASION AND METASTASIS OF HEPATOCELLULARCARCINOMA : -IN VITRO STUDY-
- Principal Investigator
  
  MASAMICHI Kojiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  KURUME UNIVERSITY
SUTUDIES ON THE RELATIONSHIP BETWEEN EPIDERMAL GROWTH FACTOR FAMILY EXPRESSION AND CARCINIGENESIS AND PROGESSION OF HEPATODELLULAR CRACINOMA : A SPECIAL REFERENCE TO HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR EXPRESSION
- Principal Investigator
  
  YANO Hirohisa
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  KURUME UNIVERSITY

All 2019 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Malic enzyme 1 is a potential marker of combined hepatocellular-cholangiocarcinoma, subtypes with stem-cell features, intermediate-cell type.2019
- Author(s)
  Mihara Y, Akiba J, Ogasawara S, Kondo R, Fukushima H, Itadani H, Obara H, Kakuma T, Kusano H, Naito Y, Okuda K, Nakashima O, Yano H.
- Journal Title
  
  Hepatology Research
  
  Volume: 印刷中 Issue: 9 Pages: 1066-1075
- DOI
  10.1111/hepr.13365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15106, KAKENHI-PROJECT-18K07032
[Journal Article] Accelerated expression of a Myc target gene Mina53 in aggressive hepatocellular carcinoma2010
- Author(s)
  Ogasawara Sachiko
- Journal Title
  
  Hepatology Research 40
  
  Pages: 330-336
- NAID
  10027407969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590412
[Journal Article] Growth inhibitory effects of pegylated IFN-a2b and 5-fluorouracil in combination on renal cell carcinoma cell lines in vitro and in vivo.2008
- Author(s)
  Moriya F., Ogasawara S., Basaki Y., Akiba J., Kojiro S., Fukahori S., Ishizaki H., Nishida N., Matsuoka K., Kojiro M., Kuwano M., Yano H.
- Journal Title
  
  Int J Oncol 33
  
  Pages: 647-655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590412
[Journal Article] Growth inhibitory effects of IFN-βon human liver cancer cells in vitro and in vivo Journal of Interferon & Cytokine Research2007
- Author(s)
  Ogasawara S, Yano H, Momosaki S, Akiba J, Nishida N, Kojiro S, Moriya F, Ishizaki H, Kuratomi K, Kojiro M.
- Journal Title
  
  27
  
  Pages: 507-516
- Data Source
  KAKENHI-PROJECT-19590412
[Journal Article] X-linked inhibitor of apoptosis (XIAP) and XIAP-associated factor-1 expression and their relationship to apoptosis in human hepatocellular carcinoma and non-carcinomatous liver tissues Oncology Reports2007
- Author(s)
  Sakemi, R, Yano H, Ogasawara S, Akiba J, Nakashima O, Fukahori S, Michio S, Kojiro M.
- Journal Title
  
  18
  
  Pages: 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590412
[Presentation] Malic enzyme 1（ME1）は混合型肝癌中間細胞亜型の診断マーカーとして有用である2019
- Author(s)
  三原勇太郎、秋葉純、小笠原幸子、近藤礼一郎、福嶋浩人板谷啓、草野弘宣、内藤嘉紀、中島収、矢野博久
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07032
[Presentation] Malic enzyme 1 is a potential marker of combined hepatocellular-cholangiocarcinoma, subtypes with stem-cell features, intermediate-cell type2019
- Author(s)
  Hirohisa Yano, Yutaro Mihara, Jun Akiba, Sachiko Ogasawara
- Organizer
  2019 Annual Meeting of Laennec Liver Pathology Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07032
[Presentation] Malic enzyme 1（ME1）は混合型肝癌中間細胞亜型の診断マーカーとして有用である2019
- Author(s)
  三原勇太郎、秋葉純、小笠原幸子、近藤礼一郎、福嶋浩人、板谷啓，草野弘宣、内藤嘉紀、中島収、矢野博久
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07032
[Presentation] シグナル伝達分子阻害剤単独あるいはインターフェロンとの併用による肝癌細胞の増殖抑制効果の検討2009
- Author(s)
  小笠原幸子, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-19590412
[Presentation] Expression of RecQL1 helicase in hepatocellular carcinoma2009
- Author(s)
  Ogasawara Sachiko
- Organizer
  Annual Meeting of International Liver cancer Association
- Place of Presentation
  Milan, Italy
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-19590412
[Presentation] 肝細胞癌におけるRecQL1ヘリカーゼ発現の臨床病理学的検討2009
- Author(s)
  小笠原幸子, 他
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-19590412
[Presentation] Expression of RecQL1 helicase in hepatocellular carcinoma.2009
- Author(s)
  Ogasawara S., et al.
- Organizer
  Annual Meeting of International Liver cancer Association.
- Place of Presentation
  Milan, Italy
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-19590412
[Presentation] ペグインターフェロン-α2bにより肝細胞癌株に誘導されるアポトーシス及び細胞周期関連遺伝子の変化に関する研究2008
- Author(s)
  小笠原幸子, 他
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590412

1. YANO Hirohisa (40220206)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. KOJIRO Masamichi (90080580)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. AKIBA Jun (00341305)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. IEMURA Akihiro (40212724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HIGAKI Koichi (40289385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MOMOSAKI Seiya (40279138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三原勇太郎 (20869086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 草野弘宣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogasawara Sachiko 小笠原 幸子

小笠原 幸子 オガサワラ サチコ

OGASAWARA Sachiko 小笠原 幸子

Research Projects

Research Products

Co-Researchers

Identification of key molecules controlling portal vein invasion of hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of diagnostic marker of combined hepatocellular-cholangiocarcinoma subtypes by gene expression analysis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic studies on the treatment and prevention of hepatocellular carcinoma with interferon

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research on anti-tumor effects of Interferon-α on hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDIES ON THE EXPRESSION OF FACTORS RELATED WITH INVASION AND METASTASIS OF HEPATOCELLULARCARCINOMA : -IN VITRO STUDY-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SUTUDIES ON THE RELATIONSHIP BETWEEN EPIDERMAL GROWTH FACTOR FAMILY EXPRESSION AND CARCINIGENESIS AND PROGESSION OF HEPATODELLULAR CRACINOMA : A SPECIAL REFERENCE TO HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR EXPRESSION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Malic enzyme 1 is a potential marker of combined hepatocellular-cholangiocarcinoma, subtypes with stem-cell features, intermediate-cell type.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accelerated expression of a Myc target gene Mina53 in aggressive hepatocellular carcinoma2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Growth inhibitory effects of pegylated IFN-a2b and 5-fluorouracil in combination on renal cell carcinoma cell lines in vitro and in vivo.2008

Author(s)

Journal Title

Data Source

[Journal Article] Growth inhibitory effects of IFN-βon human liver cancer cells in vitro and in vivo Journal of Interferon & Cytokine Research2007

Author(s)

Journal Title

Data Source

[Journal Article] X-linked inhibitor of apoptosis (XIAP) and XIAP-associated factor-1 expression and their relationship to apoptosis in human hepatocellular carcinoma and non-carcinomatous liver tissues Oncology Reports2007

Author(s)

Journal Title

Data Source

[Presentation] Malic enzyme 1（ME1）は混合型肝癌中間細胞亜型の診断マーカーとして有用である2019

Author(s)

Organizer

Data Source

[Presentation] Malic enzyme 1 is a potential marker of combined hepatocellular-cholangiocarcinoma, subtypes with stem-cell features, intermediate-cell type2019

Author(s)

Organizer

Data Source

[Presentation] Malic enzyme 1（ME1）は混合型肝癌中間細胞亜型の診断マーカーとして有用である2019

Author(s)

Organizer

Data Source

[Presentation] シグナル伝達分子阻害剤単独あるいはインターフェロンとの併用による肝癌細胞の増殖抑制効果の検討2009

Author(s)

Organizer

Place of Presentation

Ogasawara Sachiko 小笠原幸子

小笠原幸子オガサワラサチコ

OGASAWARA Sachiko 小笠原幸子