Kimura Masashi 木村正志

… Alternative Names

木村正志キムラマサシ

KIMURA Masashi 木村正志

Less

Researcher Number	40260575
Other IDs
Affiliation (Current)	2025: 岐阜大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2016: 岐阜大学, 大学院医学系研究科, 講師 2014 – 2015: 岐阜大学, 医学(系)研究科(研究院), 講師 2012: 岐阜大学, 医学(系)研究科(研究院), 助教 2009 – 2012: Gifu University, 医学系研究科, 助教 2007 – 2008: 岐阜大学, 大学院・医学系研究科, 助教 2006: 岐阜大学, 大学院医学研究科, 助手 1994 – 2003: 岐阜大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cell biology / Pathological medical chemistry Except Principal Investigator Pathological medical chemistry / Biological Sciences / General medical chemistry / General medical chemistry / Orthopaedic surgery / Cell biology
Keywords	Principal Investigator 細胞分裂 / 染色体分配 / 中心体 / 転写制御 / 細胞死 / オーロラキナーゼ / がん / 膀胱癌 / 大腸癌 / NIMA … More / Aurora / breast caencer / chromosome mapping / chromosome segregation / centrosome / cell division / 大腸ガン / 乳ガン … More Except Principal Investigator centrosome / dominant negative / cell cycle / breast cancer / chromosome mapping / NEK / histone H3 / cell division / Aurora / ipl-related kinase) / nuclear localization / RXR / RING-finger / RNF8 / ARA54 / yeast two-hybrid / UBE2E2 / phosphorylation / PIG-A / Thy-1 / FRET / colorectal cancer / bladder cancer / Aurora(AIK) / Aik (aurora / レチノイド誘導体 / リン酸化 / ユビキチン化 / RING-finger蛋白 / phosphorvlation / cell devision / Ipll-related kinase) / Aik (Aurora / dynein / Eg5 / tubulin / Ipl1-related kinase) / Aik(aurora / Ca oscillation / Cキナーゼ / ras / DGキナーゼ / ジアシルグリセロール(DG) / Caオシレーション / DNA脱メチル化 / 再生医学 / 転写活性 / Flil遺伝子 / EWS / EWS-Flil融合遺伝子 / 癌遺伝子 / 転写因子 / 骨軟部腫瘍 / オーロラキナーゼ / EWS-Fli1融合遺伝子 / ユーイング肉腫 / 蛍光顕微鏡 / GFP / NP25 / 遺伝子導入 / 3次元立体像 / 蛍光共鳴エネルギー移動 / Cdc2-cyclinB / HisotoneH3 / CDE-CHR / transcription / Centrosome / Cell division / Aurora kinase family / phosphprylation / colorectal cencer / AIK(aurora / cDNA cloning / FISH / protein degradation / Ubiquitin-conjugating enzyme Less

Role of cytidine deaminase in cell reprograming process
- Principal Investigator
  
  Nagaoka Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Gifu University
Elucidation of the function of Aurora kinases in mitosis and itsdysregulation in cancerPrincipal Investigator
- Principal Investigator
  
  KIMURA Masashi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gifu University
Analysis of Aurora Kinases in bone and soft tissue tumors
- Principal Investigator
  
  OONO Takatoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gifu University
ヒトAuroraおよび細胞分裂関連蛋白質の機能解析
- Principal Investigator
  
  岡野幸雄
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
3次元蛍光共鳴エネルギー移動法による細胞内タンパク質間相互作用の解析
- Principal Investigator
  
  武藤吉徳
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Gifu University
AIKキナーゼファミリーの癌細胞における発現と機能解析
- Principal Investigator
  
  岡野幸雄
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
Molecular mechanism of steroid receptor ubiquitination
- Principal Investigator
  
  OKANO Yukio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gifu University
AIKキナーゼファミリーの癌細胞における発現と機能
- Principal Investigator
  
  岡野幸雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
ヒトAIKファミリータンパク質の細胞分裂における機能の解析Principal Investigator
- Principal Investigator
  
  木村正志
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Gifu University
Expression of AIK family in normal and cancer tissues
- Principal Investigator
  
  YOSHIOKA Takashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Gifu University
中心体キナーゼAikファミリーのがん細胞における発現
- Principal Investigator
  
  岡野幸雄
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gifu University
ヒト中心体キナーゼAikの細胞分裂における役割
- Principal Investigator
  
  岡野幸雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gifu University
Aikの染色体分配における機能の解析とAikファミリーのcDNAクローニングPrincipal Investigator
- Principal Investigator
  
  木村正志
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Gifu University
Functional analysis of a novel human kinase, Aik, involved in chromosome segregation.
- Principal Investigator
  
  OKANO Yukio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gifu University
新規ヒトユビキチン結合酵素遺伝子の単離と細胞機能における役割の解析
- Principal Investigator
  
  OKANO Yukio
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gifu University
Analysis of molecular mechanisms for suppression of Thy-1 expression in ras-transformed cells.
- Principal Investigator
  
  OKANO Yukio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gifu University

All 2016 2013 2012 2011 2009 2008 2007

All Journal Article Presentation

[Journal Article] Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis.2016
- Author(s)
  Sato, K., Kimura, M., Sugiyama, K., Nishikawa, M., Okano, Y., Nagaoka, H., Nagase, T., Kitade, Y., and Ueda, H.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Issue: 48 Pages: 25227-25238
- DOI
  10.1074/jbc.m116.759571
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460363, KAKENHI-PROJECT-15K07927, KAKENHI-PROJECT-15K19005
[Journal Article] Identification of a Rho family specificguanine nucleotide exchange factorFLJ00018, as a novel actin-bindingprotein2013
- Author(s)
  Sato, K., Handa, H., Kimura, M., Okano,Y., Nagaoka, H., Nagase, T., Sugiyama,T., Kitade, Y., and Ueda, H.
- Journal Title
  
  Cell. Signal.
  
  Volume: 25 Issue: 1 Pages: 41-49
- DOI
  10.1016/j.cellsig.2012.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590331, KAKENHI-PROJECT-23590073, KAKENHI-PROJECT-23659151, KAKENHI-PUBLICLY-23118513
[Journal Article] Mitotic catastrophe and cell deathinduced by depletion of centrosomalproteins2013
- Author(s)
  Kimura, M., Yoshioka, T., Saio, M.,Banno, Y., Nagaoka, H., and Okano, Y
- Journal Title
  
  Cell Death Dis
  
  Volume: 4 Issue: 4 Pages: e603-e603
- DOI
  10.1038/cddis.2013.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590331, KAKENHI-PROJECT-23659151
[Journal Article] Growth suppression and mitotic defect inducedby JNJ-7706621, an inhibitor ofcyclin-dependent kinases and aurorakinases2012
- Author(s)
  Matsuhashi, A., Ohno, T., Kimura, M.,Hara, A., Saio, M., Nagano, A., Kawai,G., Saitou, M., Takigami, I., Yamada, K.,Okano, Y., and Shimizu, K
- Journal Title
  
  Curr. Cancer. Drug. Targets.
  
  Volume: 12 Pages: 625-639
- URL
  http://www.eurekaselect.com/98883/article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590331
[Journal Article] Plk1 is negativelyregulated by RNF8. Biochem2011
- Author(s)
  Yoshioka, T., Kimura, M., Saio, M., Era,S., and Okano, Y
- Journal Title
  
  Biophys.Res. Commun.
  
  Volume: 410 Issue: 1 Pages: 57-6
- DOI
  10.1016/j.bbrc.2011.05.104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590331, KAKENHI-PROJECT-22590203
[Journal Article] Effects ofAZD1152, a selective Aurora B kinaseinhibitor, on Burkitt's and Hodgkin's lymphomas2011
- Author(s)
  Mori, N., Ishikawa, C., Senba, M.,Kimura, M., and Okano, Y.
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 81 Issue: 9 Pages: 1106-1115
- DOI
  10.1016/j.bcp.2011.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590331
[Journal Article] Aberrantpromoter hypermethylation of the CHFRgene in oral squamous cell carcinomas.2009
- Author(s)
  Baba, S., Hara, A., Kato, K., Long, N.K.,Hatano, Y., Kimura, M., Okano, Y.,Yamada, Y., and Shibata, T
- Journal Title
  
  Oncol. Rep.
  
  Volume: 22 Pages: 1173-1179
- URL
  http://www.spandidos-publications.com/or/22/5/1173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590331
[Journal Article] EWS-Flil Up-Regulates Expression of the Aurora A and Aurora B Kinases2008
- Author(s)
  Wakahara K., Ohno T. Kimura M., et al.
- Journal Title
  
  Mol. Cancer Res. 6
  
  Pages: 1937-1945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591628
[Journal Article] EWS-Fli1 Up-Regulates Expression of the Aurora A and Aurora B Kinases Mol2008
- Author(s)
  Wakahara K., Ohno T. Kimura M. et.al.
- Journal Title
  
  Cancer Res 6
  
  Pages: 1937-1945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591628
[Presentation] EWS /Flil Fusion Gene Upregulate Aurora A Transcriptional Activity In Ewing's Tumor.2008
- Author(s)
  Wakahara K., Ohno T. Kimura M., et al.
- Organizer
  54th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-03-04
- Data Source
  KAKENHI-PROJECT-18591628
[Presentation] EWS /Fli1 Fusion Gene Upregulate Aurora A Transcriptional Activity In Ewings Tumor2008
- Author(s)
  Wakahara K., Ohno T. Kimura M. et.al.
- Organizer
  54th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-03-04
- Data Source
  KAKENHI-PROJECT-18591628
[Presentation] EWS/Fli1 fusion gene upregulate Aurora B transcriptional activity in Ewing's tumors2007
- Author(s)
  Wakahara K., Ohno T., Kimura K., Masuda T., Yamamoto T., Shimizu K.
- Organizer
  6th Combined Meeting of the Orthopaedic Research Societies
- Place of Presentation
  ハワイホノルルコンベンションセンター
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-18591628

1. OKANO Yukio (10177066)

# of Collaborated Projects: 12 results

# of Collaborated Products: 6 results
2. YOSHIOKA Takashi (20311699)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. 武藤吉徳 (80190859)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OONO Takatoshi (60281052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. Nagaoka Hitoshi (20270647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 鷲見典子 (60273140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤克哉 (60733508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Kimura Masashi 木村 正志

木村 正志 キムラ マサシ

KIMURA Masashi 木村 正志

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the function of Aurora kinases in mitosis and itsdysregulation in cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒトAIKファミリータンパク質の細胞分裂における機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Aikの染色体分配における機能の解析とAikファミリーのcDNAクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Kimura Masashi 木村正志

木村正志キムラマサシ

KIMURA Masashi 木村正志