Mochizuki Takatoshi 望月貴年

… Alternative Names

望月貴年モチヅキタカトシ

MOCHIZUKI Takatoshi 望月貴年

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Researcher Number	40263933
Other IDs	https://orcid.org/0000-0001-6976-7240
Affiliation (Current)	2026: 筑波大学, 国際統合睡眠医科学研究機構, 特任教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 筑波大学, 国際統合睡眠医科学研究機構, 教授 2023: 富山大学, 学術研究部教育研究推進系, 教授 2021 – 2022: 富山大学, 学術研究部理学系, 教授 2000: Osaka Biosci.Inst., 2<@D1nd@>D1.dept., Research Associate, 第2研究部, 研究員 1999: 財団法人大阪バイオサイエンス研究所, 第2研究部, 研究員 1998: (財)大阪バイオサイエンス研究所, 第2研究部, 研究員 1995 – 1997: 愛媛大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Basic Section 46030:Function of nervous system-related Except Principal Investigator Basic Section 47040:Pharmacology-related / Structural biochemistry / Functional biochemistry / General pharmacology
Keywords	Principal Investigator 睡眠 / ヒスタミン / 冬期うつ病 / オレキシン / 季節性感情障害 / 脳波 / 覚醒 / グラスラット / 昼行性動物 / くも膜下腔 … More / 吻側前脳基底部 / マイクロダイアリシス法 / DP受容体 / プロスタグランジンD_2 / アデノシン / H3-受容体 / グルタミン酸脱水素酵素 / グルタミン酸 / fusasome / synaptosome … More Except Principal Investigator 肥満細胞 / 睡眠 / Th2 cytokine / eosinophil / transgenic mouse / prostaglandin D2 / Th2サイトカイン / 好酸球 / トランスジェニックマウス / プロスタグランジンD2 / 死後脳 / iPS / 躁 / うつ / 動物モデル / うつ状態 / 躁状態 / GWAS / 躁うつ / 睡眠障害 / 脳波 / 躁うつ状態 / 髄鞘 / マウス / そう様症状 / うつ様症状 / 行動実験 / 脳波測定 / モデルマウス / 双極性障害 / ODZ4 / sleep / allergy / enzyme inhibitor / X-ray'crystallography / アレルギー / 酵素阻害剤 / 結晶構造解析 / receptor / knockout mouse / mast cell / 受容体 / ノックアウトマウス / MAST CELL DEFICIENT RATS / PAW EDEMA / RESTRAINT STRESS / GASTRIC SECRETION / IN VIVO MICRODIALYSIS / N^<tau>-METHYLHISTAMINE / HISTAMINE / MAST CELLS / ヒスタミン・ニューロン / N^7N-メチルヒスタミン / 炎症 / N^t-メチルヒスタミン / 足蹠浮腫 / N^τ-メチルヒスタミン / マイクロダイアリシス法 / 拘束水浸ストレス / 胃酸分泌 / 肥満細胞欠損ラット / ヒスタミン Less

Diurnal grass rats as a novel animal model of seasonal affective disorderPrincipal Investigator
- Principal Investigator
  
  望月貴年
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  University of Tsukuba
Production of a bipolar model mice and clarification of the neuronal mechanism of the manic switch
- Principal Investigator
  
  Nitta Atsumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  University of Toyama
Designing of inhibitors for prostaglandin D synthases based on crystallographic analyses
- Principal Investigator
  
  URADE Yoshihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE
プロスタグランジンD_2によるアデノシン遊離の調節と睡眠誘発機構についてPrincipal Investigator
- Principal Investigator
  
  望月貴年
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka Bioscience Institute
Novel function of prostaglandin D2 and its metabolites in pathogenesis of immune and allergic diseases as examined by prostaglandin D synthase gene-manipulated mice
- Principal Investigator
  
  URADE Yoshihiro, PINZAR Elena I.
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka Bioscience Institute
新しい神経終末膜標本fusasomeを用いたシナプス前受容体の電気生理学的検討Principal Investigator
- Principal Investigator
  
  望月貴年
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka Bioscience Institute
  Ehime University
NEW DEVELOPMENT OF PHARMACOLOGICAL RESEARCH FOR HISTAMINE : USING MAST CELL DEFICIENT RAT
- Principal Investigator
  
  MAEYAMA Kazutaka
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  EHIME UNIVERSITY

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Pharmacological inhibition of histamine N-methyltransferase extends wakefulness and suppresses cataplexy in a mouse model of narcolepsy2024
- Author(s)
  Naganuma Fumito、Girgin Birkan、Agu Anne Bernadette S、Hirano Kyosuke、Nakamura Tadaho、Yanai Kazuhiko、Vetrivelan Ramalingam、Mochizuki Takatoshi、Yanagisawa Masashi、Yoshikawa Takeo
- Journal Title
  
  SLEEP
  
  Volume: 48 Issue: 1 Pages: 244-244
- DOI
  10.1093/sleep/zsae244
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24070, KAKENHI-PROJECT-21K06795, KAKENHI-PROJECT-22K07373, KAKENHI-PROJECT-23K06011, KAKENHI-PROJECT-24K23228, KAKENHI-PROJECT-22K21351
[Journal Article] Sleep disturbance after cessation of cannabis administration in?mice2023
- Author(s)
  Asano Takashi、Takemoto Hiroki、Horita Tomoya、Tokutake Tomohiro、Izuo Naotaka、Mochizuki Takatoshi、Nitta Atsumi
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: - Issue: 4 Pages: 505-512
- DOI
  10.1002/npr2.12329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02632, KAKENHI-PROJECT-20K16006, KAKENHI-PROJECT-23K06011, KAKENHI-PROJECT-23K07007, KAKENHI-PROJECT-22H04922
[Presentation] Therapeutic potential of histamine N-methyltransferase inhibitors for hypersomnia disorders2025
- Author(s)
  Takeo Yoshikawa, Birkan Girgin, Kyosuke Hirano, Tadaho Nakamura, Chika Miyoshi, Takatoshi Mochizuki, Hiromasa Funato, Masashi Yanagisawa, Fumito Naganuma
- Organizer
  APPW2025
- Data Source
  KAKENHI-PROJECT-23K06011
[Presentation] ヒスタミン代謝酵素阻害薬の過眠症治療に関する有効性の検討2025
- Author(s)
  長沼史登、Girgin Birkan、平野匡佑、中村正帆、三好千香、望月貴年、船戸弘正、柳沢正史、吉川雄朗
- Organizer
  第145回日本薬学会
- Data Source
  KAKENHI-PROJECT-23K06011
[Presentation] マウス前頭前皮質におけるTeneurin-4ノックダウンの行動および睡眠への影響2023
- Author(s)
  堀田朋弥、浅野昂志、所　一輝、荒木田優輝、泉尾直孝、望月貴年、村松慎一、新田淳美
- Organizer
  第53回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-21H02632
[Presentation] 昼行性グラスラット（Arvicanthis niloticus）背側縫線核の神経活動性と睡眠覚醒調節2023
- Author(s)
  桶屋美帆、田母神さくら、天野広夢、小泉隼人、森岡絵里、Yoan Cherasse、櫻井武、吉川朋子、望月貴年、池田真行
- Organizer
  日本睡眠学会第45回定期学術集会/第30回日本時間生物学会学術大会・合同大会
- Data Source
  KAKENHI-PROJECT-23K06011
[Presentation] 昼行性グラスラットに特徴的な視床下部塩素イオン輸送体の発現とGABA受容体応答2023
- Author(s)
  田母神さくら、中川修造、五十嵐美久、中村優希、桶屋美帆、八木沢元喜、天野広夢、小泉隼人、森岡絵里、吉川朋子、望月貴年、池田真行
- Organizer
  日本睡眠学会第45回定期学術集会/第30回日本時間生物学会学術大会・合同大会
- Data Source
  KAKENHI-PROJECT-23K06011
[Presentation] 昼行性グラスラット由来の肺線維芽細胞株を用いた時計調節機構の解析2023
- Author(s)
  小泉隼人、須賀海斗、森岡絵里、吉川朋子、望月貴年、池田真行
- Organizer
  日本睡眠学会第45回定期学術集会/第30回日本時間生物学会学術大会・合同大会
- Data Source
  KAKENHI-PROJECT-23K06011
[Presentation] 前頭前皮質におけるマウスTeneuron-4発現の減少と躁うつ様症状発現の関係2023
- Author(s)
  浅野昂志、堀田朋弥、所一輝、荒木田優輝、泉尾直孝、望月貴年、村松慎一、新田淳美
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21H02632
[Presentation] CB1受容体刺激薬の離脱時における睡眠への影響2023
- Author(s)
  浅野昂志、竹本弘樹、徳竹伯洸、堀田朋弥、泉尾直孝、望月貴年、新田淳美
- Organizer
  第53回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-21H02632
[Presentation] 昼行性グラスラット（Arvicanthis niloticus）オレキシン神経の活動性と睡眠覚醒調節2023
- Author(s)
  天野広夢、田母神さくら、桶屋美帆、小泉隼人、森岡絵里、Yoan Cherasse、櫻井武、望月貴年、池田真行
- Organizer
  日本睡眠学会第45回定期学術集会/第30回日本時間生物学会学術大会・合同大会
- Data Source
  KAKENHI-PROJECT-23K06011
[Presentation] マウス大麻離脱時における睡眠の変化2022
- Author(s)
  浅野昂志, 竹本弘樹, 徳竹伯洸, 堀田朋弥, 泉尾直孝, 望月貴年, 新田淳美
- Organizer
  2022年度アルコール・薬物依存関連学会合同学術総会
- Data Source
  KAKENHI-PROJECT-21H02632

1. URADE Yoshihiro (10201360)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HAYAISHI Osamu (40025507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MAEYAMA Kazutaka (00157158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ADACHI Naoto (50253315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. GOTOH Yoshinori (10162166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMATODANI Atsushi (30116123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WATANABE Takehiko (70028356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. INOUE Thutoshi (20263204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. EGUCHI Naomi (10250086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAI Yasushi (40029236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Nitta Atsumi (20275093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. PINZAR Elena I. (80311306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 國井泰人 (00511651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 有岡祐子 (10709497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高雄啓三 (80420397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 浅野昂志 (00884751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. 泉尾直孝 (50722261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. 森岡絵里 (80756122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. YOSHIKAWA Takeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 中村正帆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 谷内一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mochizuki Takatoshi 望月 貴年

望月 貴年 モチヅキ タカトシ

MOCHIZUKI Takatoshi 望月 貴年

Research Projects

Research Products

Co-Researchers

Diurnal grass rats as a novel animal model of seasonal affective disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production of a bipolar model mice and clarification of the neuronal mechanism of the manic switch

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Designing of inhibitors for prostaglandin D synthases based on crystallographic analyses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロスタグランジンD_2によるアデノシン遊離の調節と睡眠誘発機構についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel function of prostaglandin D2 and its metabolites in pathogenesis of immune and allergic diseases as examined by prostaglandin D synthase gene-manipulated mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい神経終末膜標本fusasomeを用いたシナプス前受容体の電気生理学的検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NEW DEVELOPMENT OF PHARMACOLOGICAL RESEARCH FOR HISTAMINE : USING MAST CELL DEFICIENT RAT

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pharmacological inhibition of histamine N-methyltransferase extends wakefulness and suppresses cataplexy in a mouse model of narcolepsy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sleep disturbance after cessation of cannabis administration in?mice2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Therapeutic potential of histamine N-methyltransferase inhibitors for hypersomnia disorders2025

Author(s)

Organizer

Data Source

[Presentation] ヒスタミン代謝酵素阻害薬の過眠症治療に関する有効性の検討2025

Author(s)

Organizer

Data Source

[Presentation] マウス前頭前皮質におけるTeneurin-4ノックダウンの行動および睡眠への影響2023

Author(s)

Organizer

Data Source

[Presentation] 昼行性グラスラット（Arvicanthis niloticus）背側縫線核の神経活動性と睡眠覚醒調節2023

Author(s)

Organizer

Data Source

[Presentation] 昼行性グラスラットに特徴的な視床下部塩素イオン輸送体の発現とGABA受容体応答2023

Author(s)

Organizer

Data Source

[Presentation] 昼行性グラスラット由来の肺線維芽細胞株を用いた時計調節機構の解析2023

Author(s)

Mochizuki Takatoshi 望月貴年

望月貴年モチヅキタカトシ

MOCHIZUKI Takatoshi 望月貴年