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KAIBARA Muneshige  貝原 宗重

ORCIDConnect your ORCID iD *help
Researcher Number 40274633
External Links
Affiliation (based on the past Project Information) *help 2005: 長崎大学, 大学院・医歯薬学総合研究科, (前)助教授
2002 – 2004: Nagasaki Univ. Grad. Sch. Biomed. Sci. Ass. Prof., 大学院・医歯薬学総合研究科, 助教授
2000 – 2001: 長崎大学, 医学部, 助教授
1997 – 1999: 長崎大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
General pharmacology / General pharmacology
Except Principal Investigator
General pharmacology / General pharmacology
Keywords
Principal Investigator
patch clamp / phosphorylation / calcium channel / L-type / BHK / beta subunit / alpha subunit / A-kinase / CACNA1C / cAMP … More / リン酸化 / GABAB-R1d / GABAB-R1c / GABA / 心筋 / 遺伝子治療 / α1c / カルシュウムチャネル / BHK cell / aJpha subunit / H-89 / protein kinase A / phosphrylation / protein kinase / inactivation / Cav1.2 / Cavl2 / 培養細胞 / Cavl.2 / Protein Kinase / αAMP / カルシウムチャネル / cDNA library / GABAB receptor / GABA receptor / アフリカツメガエル / GIRK / GABA_B受容体 / 小脳 / cDNAライブラリー / GABAB受容体 / GABA受容体 … More
Except Principal Investigator
消化管運動 / GABA / GABA_B receptor / GABA_BR1d / GABA_BR1c / Xenopus oocyte / GABA-B受容体 / Confocal laser microscope / RT-PCR method / Movement in digestive tube / GABA-B2 subunit / GABA-B1 subtype / GABA-B1 subunit / Two hetero amount body / 共焦点レーザー顕微鏡 / 共焦点レーザ顕微鏡 / RT-PCR法 / GABA-B2サブユニット / GABA-B1サブタイプ / GABA-B1サブユニット / ヘテロ2量体 / in vivo microdialysis / Acetylcholine / Gastrointestinal motility / 5-Hydroxytryptamine (Serotonin) / Parasympathetic neuron / sympathetic neuron / GABA受容体 / マイクロダイアリシス / アセチルコリン / セロトニン / 副交感神経 / 交感神経 / G protein-gated inwardly rectifying K^+ channel (GIRK) / synaptophysin / dopamine release / rat brain mRNA / プロテインキナーゼC / 開口放出 / 神経終末 / γ-アミノ酪酸(GABA) / ドパミン / GIRK / GABA_BRIC / G蛋白質依存性内向き整流K^+チャネル(GIRK) / GABA_B受容体 / シナプトフィジン / ドパミン遊離 / ラット脳mRNA / アフリカツメガエル卵母細胞 / heterologous expression / Electrophysiology / FRET / G蛋白共役型受容体 / heterodimerization / 創薬 Less
  • Research Projects

    (7 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (4 People)
  •  Analysis of body GABAB receptor of two hetero amounts that makes creation of improvement of movement in digestive tube medicine target

    • Principal Investigator
      TANIYAMA Kohtaro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nagasaki University
  •  Molecular mechanism of Ca^<2+> channel activation by phosphorylation : functional regulation by phosphorylation of channel subunit CACNA1CPrincipal Investigator

    • Principal Investigator
      KAIBARA Muneshige
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nagasaki University
  •  G蛋白質共役型受容体発現調節に関わる補助因子をターゲットとした創薬研究の基盤確立

    • Principal Investigator
      TANIYAMA Kohtaro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Nagasaki University
  •  Molecular mechanisms of inactivation process of L-type Ca2+ channelPrincipal Investigator

    • Principal Investigator
      KAIBARA Muneshige
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nagasaki University Graduate School of Biomedical Science
  •  In vivo analysis of regulatory mechanism of gastrointestinal motility

    • Principal Investigator
      TANIYAMA Kohtaro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Department of Pharmacology, Nagasaki University School of Medicine
  •  Function and distribution of GABAB receptorsPrincipal Investigator

    • Principal Investigator
      KAIBARA Muneshige
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Department of Pharmacology, Nagasaki University School of Medicine
  •  Study on regulatory molecules involved in neurotransmitter release in Xenopus oocytes injected with mRNA

    • Principal Investigator
      TANIYAMA Kohtaro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nagasaki University

All 2006 2004

All Journal Article

  • [Journal Article] Coupling of the GABA_B receptor GABA_<B2> subunit to G protein : Evidence from the Xenopus oocyte and baby hamster kidney cell expression system.2006

    • Author(s)
      Uezono Y, Kanaide M, Kaibara M, Barzilai R, Dascal N, Sumikawa K, Taniyama K
    • Journal Title

      American Journal of Physiology-Cell Physiology 290

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590200
  • [Journal Article] Characterization of GABA_B Receptor in the Human Colon.2004

    • Author(s)
      Uesono Y, Kaibara M, Hayashi H, Kawakami S, Enjoji A, Kanematsu T, Taniyama K
    • Journal Title

      Journal of Pharmacological Sciences 94

      Pages: 211-213

    • NAID

      130000073876

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590200
  • [Journal Article] Characterization of GABA_B receptors involved in inhibition of motility associated with acetylcholine release in the dog small intestine : possible existence of a heterodimer of GABA_<B1> and GABA_<B2> subunits.2004

    • Author(s)
      Kawakami S, Uezono Y, Makimoto N, Enjoji A, Kaibara M, Kanematsu T, Taniyama K
    • Journal Title

      Journal of Pharmacological Sciences 94

      Pages: 368-375

    • NAID

      10012891690

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590200
  • 1.  TANIYAMA Kohtaro (70030898)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 3 results
  • 2.  UEZONO Yasuhito (20213340)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  YAMASHITA Yasuko (80291532)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  HAYASHI Hideki (10218589)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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