Nonoyama Shigeaki 野々山恵章

… Alternative Names

NONOYAMA Shigeaki 野々山恵章

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Researcher Number	40280961
Other IDs
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 小児科学, 教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 小児科学, 教授 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 小児科学, 教授 2014 – 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 教授 2012 – 2014: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 教授 2012: 防衛医科大学校, 医学教育部医学科専門課程, 教授 … More 2010 – 2011: 防衛医科大学校, 医学教育部・医学科専門課程, 教授 2010: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部・医学科専門課程, 教授 2010: 防衛医科大学校, 医学教育部医学科専門課程, 教授 2002: 防衛医科大学, 小児科, 教授 2001: Graduate School, TOKYO MEDICAL AND DENTAL UNIVERSITY, Assistant Professor, 医学部・附属病院, 助教授 2000 – 2001: Tokyo Medical and Dental University, Dept. of Developmental immunology, Lecturer, 大学院・医歯学総合研究科, 講師 1996 – 1999: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Biological Sciences Except Principal Investigator Pediatrics / Pediatrics / Biological Sciences / Basic Section 52050:Embryonic medicine and pediatrics-related / Applied pharmacology / Immunology / Hematology
Keywords	Principal Investigator アレルギー / 膠原病学 / 小児免疫 / 発生・分化 / 移植・再生医療 / 遺伝子 / 免疫学 / CD40リガンド / AID / CD40 … More / IL-4 / 感染症 / WASP / 免疫不全 / 先天異常学 / 小児神経学 / 遺伝・先天異常学 / 神経分子病態学 / 膠原病 / Primary immunodefidciency / CD40 ligand / 免疫不全症 / Allergy / FcepsilonRI / Mast cells / FcεRI / マスト細胞 / 細胞・組織 / 小児免疫・アレルギー・膠原病学 … More Except Principal Investigator 80 / CD23 / CD40 / Ku70 / ATM / gene regulation / Fcε receptor / IL-4R / class switch / CD95 / Ku / 血管炎 / 好中球 / 川崎病 / AID / 70 / Igβ / がん体質 / フレームシフト / translocation / IL-4 / DNA-PK / 好中球サブセット / サブセット / NETosis / 好中球細胞外トラップ / 細胞毒性 / ADA欠損症 / 脳神経疾患 / 神経科学 / デオキシアデノシン / アデノシンデアミナーゼ / DNA STRAND BREAKS / トポイソメラーゼ / クラススイッチ / IgE / raft / gene cloning / signal transduction / pre B cell / pro B cell / B cell differentiation / per B cell receptor (preBCR) / 急性リンパ性白血病 / 免疫グロプリン遺伝子再構成 / 胚型転写物 / 免疫グロブリン遺伝子再構成 / ラフト / 遺伝子クローニング / シグナル伝達 / プレB細胞 / プロB細胞 / B細胞分化 / プレB細胞レセプター / マススクリーニング / 重症複合免疫不全症 / degradation / 転写調節 / HMG / TCF1 / SHIP / Shc / SyK / フォスファターゼ / FcγRIIB / FcεRI / チロシンキナーゼ / 高親和性IgEレセプター / インターロイキン4 / マスト細胞 Less

川崎病血管炎における好中球サブセット動態の解析と重症度予測への応用
- Principal Investigator
  
  竹下誠一郎
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Defense Medical College
Research to elucidate the neurodegenerative disease in Chediak Higashi syndrome caused by LYST mutationPrincipal Investigator
- Principal Investigator
  
  野々山恵章
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Defense Medical College
Elucidation of pathogenesis and identification of novel causative gene of primary immunodeficiency due to PIP3-related molecular abnormality.Principal Investigator
- Principal Investigator
  
  Nonoyama Shigeaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
Neurotoxicity of deoxyadenosine and neuroprotective effects of adenosine deaminase
- Principal Investigator
  
  Ohta Hiroyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Defense Medical College
The role of neutrophil extracellular traps in the pathogenesis of Kawasaki disease
- Principal Investigator
  
  TAKESHITA SEIICHIRO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
DNA double strand break repair defects and impaired immune and neuron cell differentiations in patients with EAOH caused by APTX mutation.Principal Investigator
- Principal Investigator
  
  Nonoyama Shgeaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
Identification of novel differentiation factors in immune system using iPS cells derived from primary immunodeficiencies.Principal Investigator
- Principal Investigator
  
  NONOYAMA Shigeaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
Identification and functional analysis of the genes critical for B cell terminal differentiation in ICF syndrome.Principal Investigator
- Principal Investigator
  
  NONOYAMA Shigeaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
自己識別機構の破綻をきたす免疫不全症の病態解明と原因遺伝子同定Principal Investigator
- Principal Investigator
  
  野々山恵章
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Defense Medical College
Research for developing of a screening method for the congenital immunodeficiency by KREC/TREC to apply the method to the pathologic analysisPrincipal Investigator
- Principal Investigator
  
  NONOYAMA Shigeaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
Development of easy and cost-effective mass-screening of severe combined immunodeficiency using neonatal guthrie cards.
- Principal Investigator
  
  OSHIMA Koichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
毛細血管拡張性運動失調症の酵母による大規模スクリーニング法の開発とその応用
- Principal Investigator
  
  MIZUTANI Shuki
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical and Dental University
MOLECULAR PATHOLOGY IN DISEASES WITH DNA STRAND BREAKS AND REPAIR DEFECTS.
- Principal Investigator
  
  MIZUTANI Shuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY
免疫グロブリンクラススイッチ誘導シグナル伝達系におけるKuの役割に関する研究
- Principal Investigator
  
  森尾友宏
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
B細胞シグナル伝達系におけるKuの役割に関する研究
- Principal Investigator
  
  森尾友宏
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Study on the Molecule That Plays Critical Role in Allergic Response.
- Principal Investigator
  
  MORIO Tomohiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY
Roles of CD40/CD40 ligand molecules in human immunological disordersPrincipal Investigator
- Principal Investigator
  
  NONOYAMA Shigeaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical and Dental University
マスト細胞の活性化とそれを調節する分子機構に関する研究
- Principal Investigator
  
  MORIO Tomohiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical and Dental University
Study on B cell differentiation signaling by using a novel system
- Principal Investigator
  
  KARASUYAMA Hajime
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
  Tokyo Metropolitan Organization for Medical Research
先天性免疫不全症の責任遺伝子の解明とその機能解析Principal Investigator
- Principal Investigator
  
  野々山恵章
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
先天性免疫不全症の責任遺伝子の解明とその機能解析Principal Investigator
- Principal Investigator
  
  野々山恵章
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
Analysis of expression mechanism of FcepsilonRI on human mast cells.Principal Investigator
- Principal Investigator
  
  NONOYAMA Shigeaki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical and Dental University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Unusual clinical manifestations and predominant stopgain ATM gene variants in a single centre cohort of ataxia telangiectasia from North India2022
- Author(s)
  Rawat Amit、Tyagi Rahul、Chaudhary Himanshi、Pandiarajan Vignesh、Jindal Ankur Kumar、Suri Deepti、Gupta Anju、Sharma Madhubala、Arora Kanika、Bal Amanjit、Madaan Priyanka、Saini Lokesh、Sahu Jitendra Kumar、Ogura Yumi、Kato Tamaki、Imai Kohsuke、Nonoyama Shigeaki、Singh Surjit
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 4036-4036
- DOI
  10.1038/s41598-022-08019-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03652
[Journal Article] Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study2022
- Author(s)
  Hoshino A, Toyofuku E, Mitsuiki N, Yamashita M, Okamoto K, Yamamoto M, Kanda K, Yamato G, Keino D, Yoshimoto-Suzuki Y, Kamizono J, Onoe Y, Ichimura T, Nagao M, Yoshimura M, Tsugawa K, Igarashi T, Mitsui-Sekinaka K, Sekinaka Y, Doi T, Yasumi T, Nakazawa Y, Takagi M, Imai K, Nonoyama S, Morio T, Latour S, Kanegane H.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 784901-784901
- DOI
  10.3389/fimmu.2021.784901
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22916, KAKENHI-PROJECT-19H03614, KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-20K16942
[Journal Article] Analysis of organelles in neuronal cells differentiated from induced pluripotent stem cells of Chediak-Higashi syndrome patients.2022
- Author(s)
  Yasuko NAKAMURA, Masataka ITO, Akira SENOO, Shigeharu OH, Akira NIWA, Yasuhiro UEMURA, Tadataka TSUJI, Hidenori OHNISHI, Yasuo HORIKOSHI, Akira SHIRAISHI, Yumi OSHIRO, Masataka ISHIMURA, Osamu OHARA, Megumu K. SAITO, Ikuroh OHSAWA, Shigeaki NONOYAMA.
- Journal Title
  
  Scientific Reports
  
  Volume: 投稿中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03652
[Journal Article] The Primary Immunodeficiency Database in Japan2022
- Author(s)
  Mitsui-Sekinaka Kanako、Sekinaka Yujin、Endo Akifumi、Imai Kohsuke、Nonoyama Shigeaki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 805766-805766
- DOI
  10.3389/fimmu.2021.805766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22916, KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-20K17460, KAKENHI-PROJECT-20K16942
[Journal Article] Immunodeficiency in a patient with microcephalic osteodysplastic primordial dwarfism type I as compared to Roifman syndrome2021
- Author(s)
  Hagiwara Hidetoshi、Matsumoto Hiroshi、Uematsu Kenji、Zaha Kiyotaka、Sekinaka Yujin、Miyake Noriko、Matsumoto Naomichi、Nonoyama Shigeaki
- Journal Title
  
  Brain and Development
  
  Volume: 43 Issue: 2 Pages: 337-342
- DOI
  10.1016/j.braindev.2020.09.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-19K08289
[Journal Article] Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of Patients From India.2021
- Author(s)
  Rawat A, Vignesh P, Sudhakar M, Nonoyama S, Lau YL and Singh S, et al.
- Journal Title
  
  Front Immunol.
  
  Volume: 12 Pages: 625320-625320
- DOI
  10.3389/fimmu.2021.625320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-18K07814
[Journal Article] Hemophagocytic Lymphohistiocytosis in Children with Chronic Granulomatous Disease-Single-Center Experience from North India.2021
- Author(s)
  Vignesh P, Loganathan SK, Sudhakar M, Chaudhary H, Rawat A, Sharma M, Shekar A, Vaiphei K, Kumar N, Sachdeva MUS, Jindal AK, Suri D, Gupta A, Ray P, Imai K, Ohara O, Nonoyama S, Lau YL and Singh S.
- Journal Title
  
  J Allergy Clin Immunol Pract,
  
  Volume: 9 Issue: 2 Pages: 771-782
- DOI
  10.1016/j.jaip.2020.11.041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-18K07814
[Journal Article] Clinical and Immunological Analyses of Ten Patients with MIRAGE Syndrome.2021
- Author(s)
  Mitsui-Sekinaka K, Narumi S, Sekinaka Y, Uematsu K, Yoshida Y, Amano N, Shima H, Hasegawa T, Nonoyama S.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 41 Issue: 3 Pages: 709-711
- DOI
  10.1007/s10875-020-00964-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03627, KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-18K08527, KAKENHI-PROJECT-20K22916, KAKENHI-PROJECT-20K16942
[Journal Article] Immunological abnormalities in patients with early-onset ataxia with ocular motor apraxia and hypoalbuminemia2021
- Author(s)
  Kato Tamaki、Tamura Yoshiteru、Matsumoto Hiroshi、Kobayashi Osamu、Ishiguro Hideaki、Ogawa Masaya、Tsujikawa Koyo、Hasegawa Yasuhiro、Sakamoto Mitsuhiro、Konagaya Masaaki、Houzen Hideki、Takagi Masatoshi、Imai Kohsuke、Morio Tomohiro、Yokoseki Akio、Onodera Osamu、Nonoyama Shigeaki
- Journal Title
  
  Clinical Immunology
  
  Volume: 229 Pages: 108776-108776
- DOI
  10.1016/j.clim.2021.108776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08289, KAKENHI-PROJECT-20H03652
[Journal Article] Clinical and Genetic Profile of X-Linked Agammaglobulinemia: A Multicenter Experience From India.2021
- Author(s)
  Rawat A, Jindal AK, Suri D, Nonoyama S, Lau YL, Singh S,et al.
- Journal Title
  
  Front Immunol.
  
  Volume: 15 Pages: 612323-612323
- DOI
  10.3389/fimmu.2020.612323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-18K07814
[Journal Article] Wiskott Aldrich Syndrome: A Multi-Institutional Experience From India.2021
- Author(s)
  Suri D, Rikhi R, Jindal AK, Rawat A, Sudhakar M, Vignesh P, Gupta A, Kaur A, Sharma J, Ahluwalia J, Bhatia P, Khadwal A, Raj R, Uppuluri R, Desai M, Taur P, Pandrowala AA, Gowri V, Madkaikar MR, Lashkari HP, Bhattad S, Kumar H, Verma S, Imai K, Nonoyama S, Ohara O, Chan KW, Lee PP, Lau YL and Singh S.
- Journal Title
  
  Front. Immunol.
  
  Volume: 12 Pages: 627651-627651
- DOI
  10.3389/fimmu.2021.627651
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03652
[Journal Article] Vaccination for Patients with Inborn Errors of Immunity: a Nationwide Survey in Japan2021
- Author(s)
  Hosaka Sho、Kido Takahiro、Imagawa Kazuo、Fukushima Hiroko、Morio Tomohiro、Nonoyama Shigeaki、Takada Hidetoshi
- Journal Title
  
  Journal of Clinical Immunology
  
  Volume: 42 Issue: 1 Pages: 183-194
- DOI
  10.1007/s10875-021-01160-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03613, KAKENHI-PROJECT-20H03652
[Journal Article] Clinical, Immunological, and Molecular Features of Severe Combined Immune Deficiency: A multi-institutional experience from India.2020
- Author(s)
  Vignesh P, Rawat A, Nonoyama S, Hershfield M.S, Lau Y.L, Singh S, et al.
- Journal Title
  
  Front Immunol
  
  Volume: 11 Pages: 619146-619146
- DOI
  10.3389/fimmu.2020.619146
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-18K07814
[Journal Article] DNA ligase IV deficiency identified by chance following vaccine-derived rubella virus infection.2020
- Author(s)
  Matsumoto K, Hoshino A, Nishimura A, Kato T, Mori Y, Shimomura M, Naito C, Watanabe K, Hamazaki M, Mitsuiki N, Takagi M, Imai K, Nonoyama S, Kanegane H, Morio T.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 40 Issue: 8 Pages: 1187-1190
- DOI
  10.1007/s10875-020-00831-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03652, KAKENHI-PROJECT-18K07814
[Journal Article] Enhanced formation of neutrophil extracellular traps in Kawasaki disease2020
- Author(s)
  Yoshida Yusuke、Takeshita Seiichiro、Kawamura Yoichi、Kanai Takashi、Tsujita Yuki、Nonoyama Shigeaki
- Journal Title
  
  Pediatric Research
  
  Volume: - Issue: 6 Pages: 998-1004
- DOI
  10.1038/s41390-019-0710-3
- Data Source
  KAKENHI-PROJECT-16K10082
[Journal Article] Newborn Screening for Presymptomatic Diagnosis of Complement and Phagocyte Deficiencies.2020
- Author(s)
  Dezfouli M, Bergstrom S, Skattum L, Nonoyama S, Schwenk JM, Nilsson P, Hammarstrom L, et al.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 455-455
- DOI
  10.3389/fimmu.2020.00455
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04233, KAKENHI-PROJECT-20H03652
[Journal Article] The combination of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as a novel predictor of intravenous immunoglobulin resistance in patients with Kawasaki disease: a multicenter study.2020
- Author(s)
  Kanai T, Takeshita S, Kawamura Y, Kinoshita K, Nakatani K, Iwashima S, Takizawa Y, Hirono K, Mori K, Yoshida Y, Nonoyama S.
- Journal Title
  
  Heart Vessels.
  
  Volume: 35 Issue: 10 Pages: 1463-1472
- DOI
  10.1007/s00380-020-01622-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08295, KAKENHI-PROJECT-20K08245
[Journal Article] Allogeneic Hematopoietic Stem Cell Transplantation for Leukocyte Adhesion Deficiency2018
- Author(s)
  Horikoshi Y, Umeda K, Imai K, Yabe H, Sasahara Y, Watanabe K, Ozawa Y, Hashii Y, Kurosawa H, Nonoyama S, Morio T
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 40 Issue: 2 Pages: 137-140
- DOI
  10.1097/mph.0000000000001028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17H04233
[Journal Article] Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors2018
- Author(s)
  Oshima Koichi、Watanabe Akira、Nakahata Tatsutoshi、Saito Megumu K. et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 497 Issue: 2 Pages: 719-725
- DOI
  10.1016/j.bbrc.2018.02.139
- NAID
  120006466601
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-17K12900, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-15H05581, KAKENHI-PROJECT-15J06514, KAKENHI-PROJECT-15K06921, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-15K11072, KAKENHI-PROJECT-16K14709, KAKENHI-PROJECT-17H04233, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-15H04655
[Journal Article] Droplet Digital PCR-Based Chimerism Analysis for Primary Immunodeficiency Diseases2018
- Author(s)
  Okano Tsubasa、Tsujita Yuki、Kanegane Hirokazu、Mitsui-Sekinaka Kanako、Tanita Kay、Miyamoto Satoshi、Yeh Tzu-Wen、Yamashita Motoi、Terada Naomi、Ogura Yumi、Takagi Masatoshi、Imai Kohsuke、Nonoyama Shigeaki、Morio Tomohiro
- Journal Title
  
  Journal of Clinical Immunology
  
  Volume: 38 Issue: 3 Pages: 300-306
- DOI
  10.1007/s10875-018-0497-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04233, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-18K07814
[Journal Article] Clinical and Immunological Characterization of ICF Syndrome in Japan2018
- Author(s)
  Kamae C, Imai K, Kato T, Okano T, Honma K, Nakagawa N, Yeh TW, Noguchi E, Ohara A, Shigemura T, Takahashi H, Takakura S, Hayashi M, Honma A, Watanabe S, Shigemori T, Ohara O, Sasaki H, Kubota T, Morio T, et al.
- Journal Title
  
  J Clin Immunol
  
  Volume: 38 Issue: 8 Pages: 927-937
- DOI
  10.1007/s10875-018-0559-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-17H04233
[Journal Article] Hematopoietic Stem Cell Transplantation for Progressive Combined Immunodeficiency and Lymphoproliferation in Activated PI3K <delta> Syndrome Type 12018
- Author(s)
  Okano T, Imai K, ..., Nonoyama S, Morio T. et al.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 印刷中 Issue: 1 Pages: 266-275
- DOI
  10.1016/j.jaci.2018.04.032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-18K07818, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17H04233
[Journal Article] A Severe Anaphylactic Reaction Associated with IgM-Class Anti-Human IgG Antibodies in a Hyper-IgM Syndrome Type 2 Patient2018
- Author(s)
  Tsujita Y, Imai K, Honma K, Kamae C, Horiuchi T, Nonoyama S
- Journal Title
  
  J Clin Immunol
  
  Volume: 38 Issue: 1 Pages: 144-148
- DOI
  10.1007/s10875-017-0466-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17H04233
[Journal Article] Hematopoietic Stem Cell Transplantation for Progressive Combined Immunodeficiency and Lymphoproliferation in Activated PI3Kδ Syndrome Type 1.2018
- Author(s)
  Okano T, Imai K, Nonoyama S, et al.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04233
[Journal Article] Enhanced AKT Phosphorylation of Circulating B Cells in Patients With Activated PI3Kδ Syndrome2018
- Author(s)
  Asano Takaki、Okada Satoshi、Tsumura Miyuki、Yeh Tzu-Wen、Mitsui-Sekinaka Kanako、Tsujita Yuki、Ichinose Youjiro、Shimada Akira、Hashimoto Kunio、Wada Taizo、Imai Kohsuke、Ohara Osamu、Morio Tomohiro、Nonoyama Shigeaki、Kobayashi Masao
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 568-568
- DOI
  10.3389/fimmu.2018.00568
- NAID
  120006473827
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04233, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10112, KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-16H05355
[Journal Article] A comparison of the predictive validity of the combination of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and other risk scoring systems for intravenous immunoglobulin (ivig)-resistance in Kawasaki disease.2017
- Author(s)
  Takeshita Seiichiro, Kanai Takashi, Kawamura Yoichi, Yoshida Yusuke, Nonoyama Shigeaki
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 5 Pages: e0176957-e0176957
- DOI
  10.1371/journal.pone.0176957
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10082
[Journal Article] The role of neutrophil activation in the pathogenesis of Kawasaki disease2017
- Author(s)
  Takeshita Seiichiro, Kawamura Yoichi, Kanai Takashi,Yoshida Yusuke, Nonoyama Shigeaki
- Journal Title
  
  Pediatric Infectious Disease
  
  Volume: 3 Pages: 1-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10082
[Journal Article] Urinary Lactate Dehydrogenase Activity and Its Isozyme Patterns in Kawasaki Disease2017
- Author(s)
  Kawamura Yoichi, Takeshita Seiichiro, Kanai Takashi, Takizawa Mari, Yoshida Yusuke, Tsujita Yuki, Nonoyama Shigeaki
- Journal Title
  
  International Journal of Pediatrics
  
  Volume: 2017 Pages: 1-6
- DOI
  10.1155/2017/4162597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10082
[Journal Article] A pediatric case of acute megakaryocytic leukemia with double chimeric transcripts of CBFA2T3-GLIS2 and DHH-RHEBL12017
- Author(s)
  Mitsui-Sekinaka Kanako、Sekinaka Yujin、Ogura Yumi、Honda Mamoru、Ohyama Ryo、Oyama Chigusa、Isobe Kiyotaka、Mori Makiko、Arakawa Yuki、Koh Katsuyoshi、Hanada Ryoji、Nonoyama Shigeaki、Kawaguchi Hiroyuki
- Journal Title
  
  Leuk Lymphoma
  
  Volume: Epub ahead of print Issue: 6 Pages: 1-3
- DOI
  10.1080/10428194.2017.1387901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09729, KAKENHI-PROJECT-26461601, KAKENHI-PROJECT-17H04233
[Journal Article] Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations.2017
- Author(s)
  Hoshino A, Okada S, Yoshida K, Nishida N, Okuno Y, Ueno H, Yamashita M, Okano T, Tsumura M, Nishimura S, Sakata S, Kobayashi M, Nakamura H, Kamizono J, Mitsui-Sekinaka K, Ichimura T, Ohga S, Nakazawa Y, Takagi M, Imai K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kojima S, Nonoyama S, Morio T, Kanegane H.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: - Issue: 1 Pages: 390-400
- DOI
  10.1016/j.jaci.2016.09.029
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26293244, KAKENHI-PROJECT-26293250, KAKENHI-PROJECT-26461570, KAKENHI-PROJECT-15K15386, KAKENHI-PROJECT-15K21189, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K10112, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H05355, KAKENHI-PROJECT-16K15528
[Journal Article] Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.2016
- Author(s)
  Cantaert T, Schickel J, Bannock, Ng Y, Massad C, Delmotte F, Yamakawa N, Glauzy S, Chamberlain N, Kinnunen T, Menard L, Lavoie A, Walter J, Notarangelo L, Bruneau J, Al-Herz W, Kilic S, Ochs H, Cunningham-Rundles C, Burg M, Kuijpers T, Kracker S, Kaneko H, Sekinaka Y, Nonoyama S, Durandy A, and Meffre E.
- Journal Title
  
  J Clin Invest.
  
  Volume: 126 Issue: 11 Pages: 4289-4302
- DOI
  10.1172/jci84645
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293250, KAKENHI-PROJECT-15K15396
[Journal Article] The Combined Usefulness of the Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Predicting Intravenous Immunoglobulin Resistance with Kawasaki Disease2016
- Author(s)
  Kawamura Yoichi, Takeshita Seiichiro, Kanai Takashi, Yoshida Yusuke, Nonoyama Shigeaki
- Journal Title
  
  Journal of Pediatrics
  
  Volume: 178 Pages: 281-284
- DOI
  10.1016/j.jpeds.2016.07.035
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10082
[Journal Article] International Consensus Document (ICON): Common Variable Immunodeficiency Disorders.2016
- Author(s)
  Bonilla FA, Barlan I, Chapel H, Costa-Carvalho BT, Cunningham-Rundles C, de la Morena MT, Espinosa Rosales FJ, Hammarström L, Nonoyama S, Quinti I, Routes JM, Tang ML, Warnatz K.
- Journal Title
  
  J Allergy Clin Immunol Pract.
  
  Volume: 4 Issue: 1 Pages: 38-59
- DOI
  10.1016/j.jaip.2015.07.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293250, KAKENHI-PROJECT-15K15396
[Journal Article] Hematopoietic Stem Cell Transplantation for X-Linked Thrombocytopenia With Mutations in the WAS gene.2015
- Author(s)
  Oshima K, Imai K, Albert M.H, Bittner T.C, Strauss G, Filipovich A.H, Morio T, Kapoor N, Dalal J, Schultz K.R, Casper J.T, Notarangelo L.D, Ochs H.D, Nonoyama S.
- Journal Title
  
  J Clin Immunol
  
  Volume: 35 Issue: 1 Pages: 15-21
- DOI
  10.1007/s10875-014-0105-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15396, KAKENHI-PROJECT-26293250
[Journal Article] Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance.2015
- Author(s)
  Cantaert T, Schickel JN, Bannock JM, Ng YS, Massad C, Oe T, Wu R, Lavoie A, Walter JE, Notarangelo LD, Al-Herz W, Kilic SS, Ochs HD, Nonoyama S, Durandy A, Meffre E.
- Journal Title
  
  Immunity
  
  Volume: 17; 43 Issue: 5 Pages: 884-95
- DOI
  10.1016/j.immuni.2015.10.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15396, KAKENHI-PROJECT-26293250
[Journal Article] RAG1 Deficiency May Present Clinically as Selective IgA Deficiency.2015
- Author(s)
  Kato T, Crestani E, Kamae C, Honma K, Yokosuka T, Ikegawa T, Nishida N, Kanegane H, Wada T, Yachie A, Ohara O, Morio T, Notarangelo LD, Imai K, Nonoyama S.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 35(3) Issue: 3 Pages: 280-8
- DOI
  10.1007/s10875-015-0146-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293244, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-15K09642, KAKENHI-PROJECT-15K15396, KAKENHI-PROJECT-26461567, KAKENHI-PROJECT-26293250
[Journal Article] Clinical features and hematopoietic stem cell transplantation for CD40 ligand deficiency in Japan2015
- Author(s)
  Mitsui-Sekinaka K, Imai K, Sato H, Tomizawa D, Kajiwara M, Nagasawa M, Morio T, Nonoyama S
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: - Issue: 4 Pages: 1018-1024
- DOI
  10.1016/j.jaci.2015.02.020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591541, KAKENHI-PROJECT-15K09639, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-15K15396, KAKENHI-PROJECT-26461567, KAKENHI-PROJECT-26293250
[Journal Article] Primary immunodeficiency diseases: an update on the classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency.2014
- Author(s)
  Al-Herz W, Bousfiha A, Casanova JL, Chatila T, Conley ME, Cunningham-Rundles C, Etzioni A, Franco JL, Boby Gaspar H, Holland SM, Klein C, Nonoyama S, Ochs HD,
- Journal Title
  
  Front Immunol.
  
  Volume: 162 Pages: 1-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Analysis of somatic hypermutation in the IgM switch region in human B cells.2014
- Author(s)
  Horiuchi K, Imai K, Mitsui-Sekinaka K, Yeh ZW, Ochs HD, Durandy A, Nonoyama S.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] The soluble ST2 and NT-proBNP combination, a useful biomarker for predicting prognosis of childhood pulmonary arterial hypertension.2014
- Author(s)
  Chida A, Sato H, Shintani M, Nakayama T, Kawamura Y, Furutani Y, Inai K, Saji T, Matsuoka R, Nonoyama S, Nakanishi T.
- Journal Title
  
  Circ J.
  
  Volume: 78 Pages: 436-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Galectin-9 enhances cytokine secretion, but suppresses survival and degranulation, in human mast cell line2014
- Author(s)
  Kojima R, Ohno T, Iikura M, Niki T, Hirashima M, Iwaya K, Tsuda H, Nonoyama S, Matsuda A, Saito H, Matsumoto K, Nakae S
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 1 Pages: e86106-e86106
- DOI
  10.1371/journal.pone.0086106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390262, KAKENHI-PROJECT-23591666, KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-25670484, KAKENHI-PROJECT-26257506
[Journal Article] Efficacy and Safety of IgPro20, a Subcutaneous Immunoglobulin, in Japanese Patients with Primary Immunodeficiency Diseases.2014
- Author(s)
  Kanegane H, Imai K, Yamada M, Takada H, Ariga T, Bexon M, Rojavin M, Hu W, Kobayashi M, Lawo JP, Nonoyama S, Hara T, Miyawaki T.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 34 Pages: 204-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Mutations of NOTCH3 in childhood pulmonary arterial hypertension.2014
- Author(s)
  Chida A, Shintani M, Matsushita Y, Sato H, Eitoku T, Nakayama T, Furutani Y, Hayama E, Kawamura Y, Inai K, Ohtsuki S, Saji T, Nonoyama S, Nakanishi T.
- Journal Title
  
  Mol Genet Med.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] ACVRL1 Gene Variant in a Patient with Vein of Galen Aneurysmal Malformation.2014
- Author(s)
  Chida A, Shintani M, Wakamatsu H, Tsutsumi Y, Iizuka Y, Kawaguchi N, Furutani Y, Inai K, Nonoyama S, Nakanishi T.
- Journal Title
  
  J Pediatr Genet.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Maternal mosaicism of an ANKH mutation in a family with craniometaphyseal dysplasia2013
- Author(s)
  Kato T, Matsumoto H, Chida A, Wakamatsu H, Nonoyama S.
- Journal Title
  
  Pediatrics international.
  
  Volume: 55 Pages: 254-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Impaired KLHL3-Mediated Ubiquitination of WNK4 Causes Human Hypertension.2013
- Author(s)
  Wakabayashi M, Mori T, Isobe K. Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S.
- Journal Title
  
  Cell Reports.
  
  Volume: 3 Pages: 858-868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Factors Associated with Steroid Phobia in Caregivers of Children with Atopic Dermatitis.2013
- Author(s)
  Kojima R, Fujiwara T, Matsuda A, Narita M, Matsubara O, Nonoyama S, Ohya Y, Saito H, Matsumoto K.
- Journal Title
  
  Pediatr Dermatol.
  
  Volume: 30 Issue: 1 Pages: 29-35
- DOI
  10.1111/j.1525-1470.2012.01808.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23390262, KAKENHI-PROJECT-23591666
[Journal Article] CUL3 gene analysis enables early intervention for pediatric pseudohypoaldosteronism type II in infancy.2013
- Author(s)
  Osawa M, Ogura Y, Isobe K, Uchida S, Nonoyama S and Kawaguchi H.
- Journal Title
  
  Pediatr Nephrol.
  
  Volume: 28 Pages: 1881-1884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Neonatal herpes encephalitis caused by a virologically confirmed acyclovir resistant herpes simplex virus type 12013
- Author(s)
  Kakiuchi S, Nonoyama S, Wakamatsu H, Kogawa K, Wang L, Kinoshita-Yamaguchi H, Takayama-Ito M, Lim CK, Inoue N, Mizuguchi M, Igarashi T, Saijo M
- Journal Title
  
  J. Clin. Microbiol
  
  Volume: 51 Issue: 1 Pages: 356-9
- DOI
  10.1128/jcm.02247-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-24390258, KAKENHI-PROJECT-24591591
[Journal Article] Chronic Granulomatous Disease: Two Decades of Experience From a Tertiary Care Centre in North West India.2013
- Author(s)
  Rawat A, Singh S, Suri D, Gupta A, Saikia B, Minz RW, Sehgal S, Vaiphei K, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O,
- Journal Title
  
  J Clin Immunol.
  
  Volume: 33 Pages: 857-864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Development of enzyme-linked immunosorbent assays for urinary thiazide-sensitive Na-Cl cotransporter (NCC) measurement.2013
- Author(s)
  Isobe K, Mori T, Asano T, Kawaguchi H, Nonoyama S, Kumagai N, Kamada F, Morimoto T, Hayashi M, Sohara E, Rai T, Sasaki S, Uchida S.
- Journal Title
  
  Am J Physiology Renal Physiology.
  
  Volume: 305 Pages: 1374-1381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] A phenotypic approach for IUIS PID classification and diagnosis: guidelines for clinicians at the bedside.2013
- Author(s)
  Bousfiha AA, Jeddane L, Ailal F, Al Herz W, Conley ME, Cunningham-Rundles C, Etzioni A, Fischer A, Franco JL, Geha RS, Hammarström L, Nonoyama S, Ochs HD, Roifman CM, Seger R, Tang ML, Puck JM, Chapel H, Notarangelo LD, Casanova JL.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 33 Pages: 1078-1087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Common variable immunodeficiency classification by quantifying T-cell receptor and immunoglobulin κ-deleting recombination excision circles.2013
- Author(s)
  Kamae C, Nakagawa N, Sato H, Honma K, Mitsuiki N, Ohara O, Kanegane H, Pasic S, Pan-Hammarstrom Q, van Zelm MC, Morio T, Imai K, Nonoyama S.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 131 Pages: 1437-1440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Neonatal herpes encephalitis caused by a virologically confirmed acyclovir resistant herpes simplex virus type 1.2013
- Author(s)
  Kakiuchi S, Nonoyama S, Wakamatsu H, Kogawa K, Wang L, Kinoshita-Yamaguchi H, Takayama-Ito M, Lim CK, Inoue N, Mizuguchi M, Igarashi T, Saijo M.
- Journal Title
  
  J. Clin. Microbiol.
  
  Volume: 51 Pages: 356-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670484
[Journal Article] Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension.2013
- Author(s)
  Wakabayashi M
- Journal Title
  
  Cell Rep.
  
  Volume: 28 Issue: 3 Pages: 858-868
- DOI
  10.1016/j.celrep.2013.02.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249047, KAKENHI-PROJECT-22249032, KAKENHI-PROJECT-22390168, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24659413, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406
[Journal Article] Missense Mutations of the BMPR1B (ALK6) Gene in Childhood Idiopathic Pulmonary Arterial Hypertension2012
- Author(s)
  Chida A, Shintani M, Nakayama T, Furutani Y, Hayama E, Inai K, Saji T, Nonoyama S, Nakanishi T
- Journal Title
  
  Circ J
- NAID
  10030316588
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] A dual reporter splicing assay using HaloTag-containing proteins. Curr Chem Genomics.2012
- Author(s)
  Oshima K, Nagase T, Imai K, Nonoyama S, Obara M, Mizukami T, Nunoi H, Kanegane H, Kuribayashi F, Amemiya S, Ohara O.
- Journal Title
  
  Curr Chem Genomics.
  
  Volume: 6 Issue: 1 Pages: 27-37
- DOI
  10.2174/1875397301206010027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-24591563
[Journal Article] Outcomes of Childhood Pulmonary Arterial Hypertension in BMPR2 and ALK1 Mutation Carriers2012
- Author(s)
  Chida A, Shintani M, Yagi H, Fujiwara M, Kojima Y, Sato H, Imamura S, Yokozawa M, Onodera N, Horigome H, Kobayashi T, Hatai Y, Nakayama T, Fukushima H, Nishiyama M, Doi S, Ono Y, Yasukouchi S, Ichida F, Fujimoto K, Ohtsuki S, Teshima H, Kawano T, Nomura Y, Gu H, Ishiwata T, Furutani Y, Inai K, Saji T, Matsuoka R, Nonoyama S, Nakanishi T
- Journal Title
  
  Am J Cardiol
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Hyper-eosinophilia granular acute B-cell lymphoblastic leukemia with myeloid antigen expression2012
- Author(s)
  Kobayashi D, Kogawa K, Imai K, Tanaka T, Sada A, Nonoyama S
- Journal Title
  
  Pediatr Int
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Missense Mutations of the BMPR1B (ALK6) Gene in Childhood Idiopathic Pulmonary Arterial Hypertension.2012
- Author(s)
  Chida A, Shintani M, Nakayama T, Furutani Y, Hayama E, Inai K, Saji T, Nonoyama S, Nakanishi T.
- Journal Title
  
  Circ J.
  
  Volume: 76 Pages: 1501-1508
- NAID
  10030316588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Clinical and genetic characteristics of XIAP deficiency in Japan2012
- Author(s)
  Yang X, Kanegane H, Nishida N, Imamura T, Hamamoto K, Miyashita R, Imai K, Nonoyama S, Sanayama K, Yamaide A, Kato F, Nagai K, Ishii E, Zelm M, Latour S, Zhao X, Miyawaki T
- Journal Title
  
  J Clin Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Survey of Japanese infants younger than 3 months who were treated with oseltamivir for influenza : Safety of oseltamivir treatment2012
- Author(s)
  Morioka I, Nonoyama S, Tanaka-Taya K, Ihara T, Sugaya N, Ueta I, Kumagai T, Okada K, Hosoya M, Okabe N, Morishima T
- Journal Title
  
  Scand J Infect Dis
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Functional STAT3 deficiency compromises IL-12-dependent generation of human T-follicular helper cells2012
- Author(s)
  Ma CS, Avery DT, Chan A, Batten M, Bustamante J, Boisson-Dupuis S, Arkwright PD, Minegishi Y, Nonoyama S, French MA, Choo S, Peake J, Wong M, Cook MC, Fulcher DA, Casanova JL, Deenick EK, Tangye SG
- Journal Title
  
  Blood
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Multiple reversions of an IL2RG mutation restore T cell function in an X-linked severe combined immunodeficiency patient2012
- Author(s)
  Kawai T, Saito M, Nishikomori R, Yasumi T, Izawa K, Murakami T, Okamoto S, Mori Y, Nakagawa N, Imai K, Nonoyama S, Wada T, Yachie A, Ohmori K, Nakahata T, Heike T
- Journal Title
  
  J Clin Immunol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Clinical and genetic characteristics of XIAP deficiency in Japan.2012
- Author(s)
  Yang X, Kanegane H, Nishida N, Imamura T, Hamamoto K, Miyashita R, Imai K, Nonoyama S, Sanayama K, Yamaide A, Kato F, Nagai K, Ishii E, Zelm M, Latour S, Zhao X, Miyawaki T.
- Journal Title
  
  J Clin Immunol.
  
  Volume: 32 Issue: 3 Pages: 411-420
- DOI
  10.1007/s10875-011-9638-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591561
[Journal Article] Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, north India2012
- Author(s)
  Suri D, Singh S, Rawat A, Gupta A, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Bilhou-Nabera C, Proust A, Ahluwalia J, Dogra S, Saikia B, Walker Minz R, Sehgal S
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 30 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Factors Associated with Steroid Phobia in Caregivers of Children with Atopic Dermatitis2012
- Author(s)
  Kojima R, Fujiwara T, Matsuda A, Narita M, Matsubara O, Nonoyama S, Ohya Y, Saito H, Matsumoto K
- Journal Title
  
  Pediatr Dermatol
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Hyper-eosinophilia in granular acute B-cell lymphoblastic leukemia with myeloid antigen expression.2012
- Author(s)
  Kobayashi D, Kogawa K, Imai K, Tanaka T, Sada A, Nonoyama S.
- Journal Title
  
  Pediatr Int.
  
  Volume: 54 Issue: 4 Pages: 543-546
- DOI
  10.1111/j.1442-200x.2011.03471.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591389
[Journal Article] GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia2012
- Author(s)
  Ishida H, Imai K, Homma K, Tamura S, Imamura T, Itoh M, Nonoyama S
- Journal Title
  
  Eur J Pediatr
  
  Volume: 171 Issue: 8 Pages: 1273-1276
- DOI
  10.1007/s00431-012-1715-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591547, KAKENHI-PROJECT-23591561
[Journal Article] Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis2012
- Author(s)
  Nakaoka H, Kanegane H, Taneichi H, Miya K, Yang X, Nomura K, Takezaki S, Yamada M, Ohara O, Kamae C, Imai K, Nonoyama S, Wada T, Yachie A, Hershfield MS, Ariga T, Miyawaki T
- Journal Title
  
  Int J Hematol
  
  Volume: (in press)
- NAID
  10030793746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils2012
- Author(s)
  Honda F, Kanegane H, et al
- Journal Title
  
  Nat Immunol
  
  Volume: 13 Issue: 4 Pages: 369-378
- DOI
  10.1038/ni.2234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591350, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23390270, KAKENHI-PROJECT-23659518
[Journal Article] Endocrine complications in primary immunodeficiency diseases in Japan2012
- Author(s)
  Nozaki T, Takada H, Ishimura M, Ihara K, Imai K, Morio T, Kobayashi M, Nonoyama S, Hara T
- Journal Title
  
  Clin Endocrinol
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Multiple reversions of an IL2RG mutation restore combined immunodeficiency patient.2012
- Author(s)
  Kawai T., Saito M., Nishikomori R., Yasumi T., Izawa K., Murakami T., Okamoto N., Mori Y., Nakagawa N., Imai K., Nonoyama S., Wada T., Yatie A., Oomori K., Nakahata T., Heike T.
- Journal Title
  
  J. Clin. Immunol
  
  Volume: 32(4) Issue: 4 Pages: 690-7
- DOI
  10.1007/s10875-012-9684-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23390119, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24591542, KAKENHI-PROJECT-24659496
[Journal Article] Deenick EK, Tangye SG. Functional STAT3 deficiency compromises the generation of human T follicular helper cells.2012
- Author(s)
  Ma CS, Avery DT, Chan A, Batten M, Bustamante J, Boisson-Dupuis S, Arkwright PD, Kreins AY, Averbuch D, Engelhard D, Magdorf K, Kilic SS, Minegishi Y, Nonoyama S, French MA, Choo S, Smart JM, Peake J, Wong M, Gray P, Cook MC, Fulcher DA
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 17 Pages: 3997-4008
- DOI
  10.1182/blood-2011-11-392985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390205, KAKENHI-PROJECT-22390213
[Journal Article] Outcomes of Childhood Pulmonary Arterial Hypertension in BMPR2 and ALK1 Mutation Carriers2012
- Author(s)
  Chida A, Shintani M, Yagi H, Fujiwara M, Kojima Y, Sato H, Imamura S, Yokozawa M, Onodera N, Horigome H, Kobayashi T, Hatai Y, Nakayama T, Fukushima H, Nishiyama M, Doi S, Ono Y, Yasukouchi S, Ichida F, Fujimoto K, Ohtsuki S, Teshima H, Kawano T, Nomura Y, Gu H, Ishiwata T, Furutani Y, Inai K, Saji T, Matsuoka R, Nonoyama S, Nakanishi T
- Journal Title
  
  Am J Cardiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils2012
- Author(s)
  Honda F, Kano H, Kanegane H, Nonoyama S, Kim ES, Lee SK, Takagi M, Mizutani S, Morio T
- Journal Title
  
  Nat Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.2012
- Author(s)
  Nakaoka H, Kanegane H, Taneichi H, Miya K, Yang X, Nomura K, Takezaki S, Yamada M, Ohara O, Kamae C, Imai K, Nonoyama S, Wada T, Yachie A, Hershfield MS, Ariga T, Miyawaki T.
- Journal Title
  
  Int J Hematol.
  
  Volume: 95 Issue: 6 Pages: 692-696
- DOI
  10.1007/s12185-012-1055-4
- NAID
  10030793746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-24591542
[Journal Article] NKRP1A+ γδ and αβ T cells are preferentially induced in patients with Salmonella infection.2012
- Author(s)
  Hoshina T
- Journal Title
  
  Hum Immunol
  
  Volume: 73 Issue: 4 Pages: 623-628
- DOI
  10.1111/j.1365-2265.2012.04390.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249043, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23390270, KAKENHI-PROJECT-24591515, KAKENHI-PROJECT-24591551
[Journal Article] Hyper-eosinophilia in granular acute B-cell lymphoblastic leukemia with myeloid antigen expression2012
- Author(s)
  Kobayashi D, Kogawa K, Imai K, Tanaka T, Sada A, Nonoyama S
- Journal Title
  
  Pediatr Int
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Survey of Japanese infants younger than 3 months who were treated with oseltamivir for influenza: Safety of oseltamivir treatment.2012
- Author(s)
  Morioka I, Nonoyama S, Tanaka-Taya K, Ihara T, Sugaya N, Ueta I, Kumagai T, Okada K, Hosoya M, Okabe N, Morishima T.
- Journal Title
  
  Scand J Infect Dis.
  
  Volume: 44 Issue: 8 Pages: 605-609
- DOI
  10.3109/00365548.2012.669844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia2012
- Author(s)
  Ishida H, Imai K, Homma K, Tamura S, Imamura T, Itoh M, Nonoyama S
- Journal Title
  
  Eur J Pediatr
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Factors Associated with Steroid Phobia in Caregivers of Children with Atopic Dermatitis2012
- Author(s)
  Kojima R, Fujiwara T, Matsuda A, Narita M, Matsubara O, Nonoyama S, Ohya Y, Saito H, Matsumoto K
- Journal Title
  
  Pediatr Dermatol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Endocrine complications in primary immunodeficiency diseases in Japan2012
- Author(s)
  Nozaki T, Takada H, Ishimura M, Ihara K, Imai K, Morio T, Kobayashi M, Nonoyama S, Hara T
- Journal Title
  
  Clin Endocrinol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Multiple reversions of an IL2RG mutation restore T cell function in an X-linked severe combined immunodeficiency patient2012
- Author(s)
  Kawai T, Saito M, Nishikomori R, Yasumi T, Izawa K, Murakami T, Okamoto S, Mori Y, Nakagawa N, Imai K, Nonoyama S, Wada T, Yachie A, Ohmori K, Nakahata T, Heike T
- Journal Title
  
  J Clin Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Survey of Japanese infants younger than 3 months who were treated with oseltamivir for influenza : Safety of oseltamivir treatment2012
- Author(s)
  Morioka I, Nonoyama S, Tanaka-Taya K, Ihara T, Sugaya N, Ueta I, Kumagai T, Okada K, Hosoya M, Okabe N, Morishima T
- Journal Title
  
  Scand J Infect Dis
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Clinical and genetic characteristics of XIAP deficiency in Japan2012
- Author(s)
  Yang X, Kanegane H, Nishida N, Imamura T, Hamamoto K, Miyashita R, Imai K, Nonoyama S, Sanayama K, Yamaide A, Kato F, Nagai K, Ishii E, Zelm M, Latour S, Zhao X, Miyawaki T
- Journal Title
  
  J Clin Immunol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Functional STAT3 deficiency compromises IL-12-dependent generation of human T-follicular helper cells2012
- Author(s)
  Ma CS, Avery DT, Chan A, Batten M, Bustamante J, Boisson-Dupuis S, Arkwright PD, Minegishi Y, Nonoyama S, French MA, Choo S, Peake J, Wong M, Cook MC, Fulcher DA, Casanova JL, Deenick EK, Tangye SG
- Journal Title
  
  Blood
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, north India2012
- Author(s)
  Suri D, Singh S, Rawat A, Gupta A, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Bilhou-Nabera C, Proust A, Ahluwalia J, Dogra S, Saikia B, Walker Minz R, Sehgal S
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 30 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Missense Mutations of the BMPR1B (ALK6) Gene in Childhood Idiopathic Pulmonary Arterial Hypertension2012
- Author(s)
  Chida A, Shintani M, Nakayama T, Furutani Y, Hayama E, Inai K, Saji T, Nonoyama S, Nakanishi T
- Journal Title
  
  Circ J
  
  Volume: (in press)
- NAID
  10030316588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Quantification of human herpesvirus-6 (HHV-6) DNA in a cord blood transplant recipient with chromosomal integration of HHV-62011
- Author(s)
  Kobayashi D, Kogawa K, Imai K, Tanaka T, Hiroi S, Satoh H, Tanaka-Taya K, Nonoyama S
- Journal Title
  
  Transpl Infect Dis
  
  Volume: 13 Pages: 650-653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Ulinastatin, a Urinary Trypsin Inhibitor, for the Initial Treatment of Patients with Kawasaki2011
- Author(s)
  Kanai T, Ishiwata T, Kobayashi T, Sato H, Takizawa M, Kawamura Y, Tsujimoto H, Nakatani K, Ishibashi N, Nishiyama M, Hatai Y, Asano Y, Kobayashi T, Takeshita S, Nonoyama S
- Journal Title
  
  Circulation
  
  Volume: 124 Pages: 2822-2828
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Primary Immunodeficiency Diseases : an update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency2011
- Author(s)
  Al-Herz W, Bousfiha A, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Fischer A, Franco JL, Geha RS, Hammarstrom L, Nonoyama S, Notarangelo LD, Ochs HD, Puck JM, Roifman C, Seger R, Tang MLK
- Journal Title
  
  Front Immun
  
  Volume: 2 Pages: 54-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Primary Immunodeficiency Diseases: an update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency2011
- Author(s)
  Al-Herz W, Bousfiha A, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Fischer A, Franco JL, Geha RS, Hammarstrom L, Nonoyama S, Notarangelo LD, Ochs HD, Puck JM, Roifman C, Seger R, Tang MLK
- Journal Title
  
  Front Immun
  
  Volume: 2 Pages: 54-54
- DOI
  10.3389/fimmu.2011.00054
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects.2011
- Author(s)
  Nakagawa N, Imai K, Kanegane H, Nonoyama S., et al.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Contribution of Sarcoplasmic Reticulum Ca2+ Release and Ca2+ Transporters on Sarcolemmal Channels to Ca2+ Transient in Fetal Mouse Heart2011
- Author(s)
  Takizawa M, Ishiwata T, Kawamura Y, Kanai T, Kurokawa T, Nishiyama M, Ishida H, Asano Y, Nonoyama S
- Journal Title
  
  Pediatr Res
  
  Volume: 69 Pages: 306-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects2011
- Author(s)
  Nakagawa N, Imai K, Kanegane H, Sato H, Yamada M, Kondoh K, Okada S, Kobayashi M, Agematsu K, Takada H, Mitsuiki N, Oshima K, Ohara O, Suri D, Rawat A, Singh S, Pan-Hammarstrom Q, Hammarstrom L, Reichenbach J, Seger R, Ariga T, Hara T, Miyawaki T, Nonoyama S
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 128 Pages: 223-225
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Early and rapid detection of X-linked lymphoproliferative syndrome with SH2D1A mutations by flow cytometry2011
- Author(s)
  Zhao M, Kanegane H, Kobayashi C, Nakazawa Y, Ishii E, Kasai M, Terui K, Gocho Y, Imai K, Kiyasu J, Nonoyama S, Miyawaki T
- Journal Title
  
  Cytometry B Clin Cytom
  
  Volume: 80 Pages: 8-13
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Ulinastatin, a Urinary Trypsin Inhibitor, for the Initial Treatment of Patients with Kawasaki2011
- Author(s)
  Kanai T, Ishiwata T, Kobayashi T, Sato H, Takizawa M, Kawamura Y, Tsujimoto H, Nakatani K, Ishibashi N, Nishiyama M, Hatai Y, Asano Y, Kobayashi T, Takeshita S, Nonoyama S
- Journal Title
  
  Circulation
  
  Volume: 124 Pages: 2822-2828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.2011
- Author(s)
  Saito M, Nagasawa M, Takada H, Nonoyama S, et al.
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 208(2) Pages: 235-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Cardiopulmonary arrest caused by craniometaphyseal dysplasia2011
- Author(s)
  Chida A, Yanagawa Y, Matsumoto H, Nonoyama S
- Journal Title
  
  Indian J Pediatr
  
  Volume: 78 Pages: 1010-1012
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Early and rapid detection of X-linked lymphoproliferative syndrome with SH2D1A mutations by flow cytometry2011
- Author(s)
  Zhao M, Kanegane H, Kobayashi C, Nakazawa Y, Ishii E, Kasai M, Terui K, Gocho Y, Imai K, Kiyasu J, Nonoyama S, Miyawaki T
- Journal Title
  
  Cytometry B Clin Cytom
  
  Volume: 80 Pages: 8-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Nationwide Survey of Patients with Primary Immunodeficiency Diseases in Japan2011
- Author(s)
  Ishimura M, Takada H, Doi T, Imai K, Sasahara Y, Kanegane H, Nishikomori R, Morio T, Heike T, Kobayashi M, Ariga T, Tsuchiya S, Nonoyama S, Miyawaki T, Hara T
- Journal Title
  
  J Clin Immunol
  
  Volume: 31 Pages: 968-976
- NAID
  120005133089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Nationwide Survey of Patients with Primary Immunodeficiency Diseases in Japan2011
- Author(s)
  Ishimura M, Takada H, Doi T, Imai K, Sasahara Y, Kanegane H, Nishikomori R, Morio T, Heike T, Kobayashi M, Ariga T, Tsuchiya S, Nonoyama S, Miyawaki T, Hara T
- Journal Title
  
  J Clin Immunol
  
  Volume: 31 Pages: 968-976
- NAID
  120005133089
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects.2011
- Author(s)
  Nakagawa N, Imai K, Kanegane H, Nonoyama S., et al.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Contribution of Sarcoplasmic Reticulum Ca2+Release and Ca2+ Transporters on Sarcolemmal Channels to Ca2+ Transient in Fetal Mouse Heart2011
- Author(s)
  Takizawa M, Ishiwata T, Kawamura Y, Kanai T, Kurokawa T, Nishiyama M, Ishida H, Asano Y, Nonoyama S
- Journal Title
  
  Pediatr Res
  
  Volume: 69 Pages: 306-311
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell2011
- Author(s)
  Nakagawa N,…, Takada H, et al
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 128 Issue: 1 Pages: 223-225
- DOI
  10.1016/j.jaci.2011.01.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591363, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591561
[Journal Article] Analysis of mutations and recombination activity in RAG-deficient patients2011
- Author(s)
  Asai E, Wada T, Sakakibara Y, Toga A, Toma T, Shimizu T, Nampoothiri S, Imai K, Nonoyama S, Morio T, Muramatsu H, Kamachi Y, Ohara O, Yachie A
- Journal Title
  
  Clin Immunol
  
  Volume: 138 Pages: 172-177
- NAID
  120002772030
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Early and rapid detection of X-linked lymphoproliferative syndrome with SH2D1A mutations by flow cytometry.2011
- Author(s)
  Zhao M, Kanegane H, Kobayashi C, Nonoyama S, et al.
- Journal Title
  
  Cytometry Part B Clinical Cytometry
  
  Volume: 80(1) Pages: 8-13
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells2011
- Author(s)
  Saito M, Nagasawa M, Takada H, Hara T, Tsuchiya S, Agematsu K, Yamada M, Kawamura N, Ariga T, Tsuge I, Nonoyama S, Karasuyama H, Minegishi Y
- Journal Title
  
  J Exp Med
  
  Volume: 208 Pages: 235-249
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells2011
- Author(s)
  Saito M,…, Takada H, et al
- Journal Title
  
  J Exp Med
  
  Volume: 208 Issue: 2 Pages: 235-249
- DOI
  10.1084/jem.20100799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591363, KAKENHI-PROJECT-22390205, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22591155, KAKENHI-PROJECT-23659511
[Journal Article] Analysis of mutations and recombination activity in RAG-deficient patients2011
- Author(s)
  Asai E, Wada T, Sakakibara Y, Toga A, Toma T, Shimizu T, Nampoothiri S, Imai K, Nonoyama S, Morio T, Muramatsu H, Kamachi Y, Ohara O, Yachie A
- Journal Title
  
  Clin Immunol
  
  Volume: 138 Issue: 2 Pages: 172-7
- DOI
  10.1016/j.clim.2010.11.005
- NAID
  120002772030
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Severe human herpesvirus 6 associated encephalopathy in three children : Analysis of cytokine profiles and the carnitine palmitoyltransferase 2 gene2011
- Author(s)
  Matsumoto H, Hatanaka D, Ogura Y, Chida A, Nakamura Y, Nonoyama S
- Journal Title
  
  Pediatr Infect Dis J
  
  Volume: 30 Pages: 999-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells2011
- Author(s)
  Saito M, Nagasawa M, Takada H, Hara T, Tsuchiya S, Agematsu K, Yamada M, Kawamura N, Ariga T, Tsuge I, Nonoyama S, Karasuyama H, Minegishi Y
- Journal Title
  
  J Exp Med
  
  Volume: 208 Pages: 235-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Early and rapid detection of X-linked lymphoproliferative syndrome with SH2D1A mutations by flow cytometry.2011
- Author(s)
  Zhao M, Kanegane H, Kobayashi C, Nonoyama S, et al.
- Journal Title
  
  Cytometry Part B Clinical Cytometry
  
  Volume: 80(1) Pages: 8-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Quantification of K-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects.2011
- Author(s)
  Nakagawa N, Imai K, Kanegane H, Sato H, Yamada M, Kondoh K, Okada S, Kobayashi M, Agematsu K, Takada H, Mitsuiki N, Oshima K, Ohara O, Suri D, Rawat A, Singh S, Pan-Hammarstrom Q, Hammarstrom L, Reichenbach J, Seger R, Ariga T, Hara T, Miyawaki T, Nonoyama S.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: (未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791018
[Journal Article] Analysis of mutations and recombination activity in RAG-deficient patients.2011
- Author(s)
  Asai E, Wada T, Sakakibara Y, Nonoyama S, et al.
- Journal Title
  
  Clinical Immunology
  
  Volume: 138(2) Pages: 172-7
- NAID
  120002772030
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Contribution of sarcoplasmic reticulum Ca^2+release and Ca^2+transporters on sarcolemmal channels to Ca^2+transient in fetal mouse heart.ouse heart.2011
- Author(s)
  Takizawa M, Ishiwata T, Kawamura Y, Nonoyama S., et al.
- Journal Title
  
  Pediatric Research
  
  Volume: 69(4) Pages: 306-11
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Contribution of sarcoplasmic reticulum Ca^2+ release and Ca^2+ transporters on sarcolemmal channels to Ca^2+ transient in fetal mouse heart.ouse heart.2011
- Author(s)
  Takizawa M, Ishiwata T, Kawamura Y, Nonoyama S., et al.
- Journal Title
  
  Pediatric Research
  
  Volume: 69(4) Pages: 306-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Cardiopulmonary arrest caused by craniometaphyseal dysplasia2011
- Author(s)
  Chida A, Yanagawa Y, Matsumoto H, Nonoyama S
- Journal Title
  
  Indian J Pediatr
  
  Volume: 78 Pages: 1010-1012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Primary Immunodeficiency Diseases : an update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency2011
- Author(s)
  Al-Herz W, Bousfiha A, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Fischer A, Franco JL, Geha RS, Hammarstrom L, Nonoyama S, Notarangelo LD, Ochs HD, Puck JM, Roifman C, Seger R, Tang MLK
- Journal Title
  
  Front Immun
  
  Volume: 2 Pages: 54-54
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Severe human herpesvirus 6 associated encephalopathy in three children : Analysis of cytokine profiles and the carnitine palmitoyltransferase 2 gene2011
- Author(s)
  Matsumoto H, Hatanaka D, Ogura Y, Chida A, Nakamura Y, Nonoyama S
- Journal Title
  
  Pediatr Infect Dis J
  
  Volume: 30 Pages: 999-1001
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Nationwide Survey of Patients with Primary Immunodeficiency Diseases in Japan2011
- Author(s)
  Ishimura M, 他
- Journal Title
  
  Journal of clinical immunology
  
  Volume: (in press) Issue: 6 Pages: 968-976
- DOI
  10.1007/s10875-011-9594-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390310, KAKENHI-PROJECT-21591363, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23659511
[Journal Article] Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.2011
- Author(s)
  Saito M, Nagasawa M, Takada H, Nonoyama S, et al.
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 208(2) Pages: 235-49
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantification of human herpesvirus-6 (HHV-6) DNA in a cord blood transplant recipient with chromosomal integration of HHV-62011
- Author(s)
  Kobayashi D, Kogawa K, Imai K, Tanaka T, Hiroi S, Satoh H, Tanaka-Taya K, Nonoyama S
- Journal Title
  
  Transpl Infect Dis
  
  Volume: 13 Pages: 650-653
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Analysis of mutations and recombination activity in RAG-deficient patients.2011
- Author(s)
  Asai E, Wada T, Sakakibara Y, Nonoyama S, et al.
- Journal Title
  
  Clinical Immunology
  
  Volume: 138(2) Pages: 172-7
- NAID
  120002772030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] A case of glycogen storage disease type Ib presenting with prolonged neonatal hypoglycaemia and minimal metabolic abnormalities.2010
- Author(s)
  Matsumoto H, Kajiwara S, Ogura Y, Asano T, Horikawa R, Nonoyama S.
- Journal Title
  
  Acta Paediatrica
  
  Volume: 99(2) Pages: 163-4
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] X-linked thrombocytopenia (XLT) due to WAS mutations : clinical characteristics, long-term outcome, and treatment options.2010
- Author(s)
  Albert MH, Bittner TC, Nonoyama S, et al.
- Journal Title
  
  Blood
  
  Volume: 115(16) Pages: 3231-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] X-linked thrombocytopenia (XLT) due to WAS mutations : clinical characteristics, long-term outcome, and treatment options.2010
- Author(s)
  Albert MH, Bittner TC, Nonoyama S, et al.
- Journal Title
  
  Blood
  
  Volume: 115(16) Pages: 3231-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Hemophagocytosis after bone marrow transplantation for JAK3-deficient severe combined immunodeficiency.2010
- Author(s)
  Hashii Y, Yoshida H, Kuroda S, Nonoyama S, et al.
- Journal Title
  
  Pediatric Transplantation
  
  Volume: 14(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease.2010
- Author(s)
  Tsuge I, Kondo Y, Nakajima Y, Nonoyama S, et al.
- Journal Title
  
  Clinical and Experimental Rheumatology
  
  Volume: 28(4) Pages: 558-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease.2010
- Author(s)
  Tsuge I, Kondo Y, Nakajima Y, Nonoyama S, et al.
- Journal Title
  
  Clinical and Experimental Rheumatology
  
  Volume: 28(4) Pages: 558-60
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] A case of glycogen storage disease type Ib presenting with prolonged neonatal hypoglycaemia and minimal metabolic abnormalities.2010
- Author(s)
  Matsumoto H, Kajiwara S, Ogura Y, Asano T, Horikawa R, Nonoyama S.
- Journal Title
  
  Acta Paediatrica
  
  Volume: 99(2) Pages: 163-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.2010
- Author(s)
  Picard C, von Bernuth H, Ghandil P, Nonoyama S, et al.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 89(6) Pages: 403-25
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantitative assessment of PTPN11 or RAS mutations at the neonatal period and during the clinical course in patients with juvenile myelomonocytic leukaemia.2010
- Author(s)
  Matsuda K, Sakashita K, Taira C, Nonoyama S, et al.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 148(4) Pages: 593-9
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantitative assessment of PTPN11 or RAS mutations at the neonatal period and during the clinical course in patients with juvenile myelomonocytic leukaemia.2010
- Author(s)
  Matsuda K, Sakashita K, Taira C, Nonoyama S, et al.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 148(4) Pages: 593-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Hemophagocytosis after bone marrow transplantation for JAK3-deficient severe combined immunodeficiency.2010
- Author(s)
  Hashii Y, Yoshida H, Kuroda S, Nonoyama S, et al.
- Journal Title
  
  Pediatric Transplantation
  
  Volume: 14(8)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Fetal and neonatal development of Ca^2+transients and functional sarcoplasmic reticulum in beating mouse hearts.2010
- Author(s)
  Kawamura Y, Ishiwata T, Takizawa M, Ishida H, Asano Y, Nonoyama S.
- Journal Title
  
  Circulation Journal
  
  Volume: 74(7) Pages: 1442-50
- NAID
  10030695829
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Ataxia-telangiectasia in a patient presenting with hyper-immunoglobulin Msyndrome.2010
- Author(s)
  Aghamohammadi A, Imai K, Moazzami K, Nonoyama S, et al.
- Journal Title
  
  Journal of Investigational Allergology and Clinical Immunology
  
  Volume: 20(5) Pages: 442-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Ataxia-telangiectasia in a patient presenting with hyper-immunoglobulin Msyndrome.2010
- Author(s)
  Aghamohammadi A, Imai K, Moazzami K, Nonoyama S, et al.
- Journal Title
  
  Journal of Investigational Allergology and Clinical Immunology
  
  Volume: 20(5) Pages: 442-5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] X-linked thrombocytopenia (XLT) due to WAS mutations:Clinical characteristics, long-term outcome and treatment options2010
- Author(s)
  Albert MH, Bittner TC, Nonoyama S, Notarangelo LD, Burns S, Imai K, Espanol T, Fasth A, Pellier I, Strauss G, MorioT ,Gathmann B, Noordzij JG, Fillat C, Hoenig M, Nathrath M, Meindl A, Pagel P, Wintergerst U, Fischer A, Thrasher AJ, Belohradsky BH, Ochs HD
- Journal Title
  
  Blood
  
  Volume: 115 Issue: 16 Pages: 3231-3238
- DOI
  10.1182/blood-2009-09-239087
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Fetal and neonatal development of Ca^2+ transients and functional sarcoplasmic reticulum in beating mouse hearts.2010
- Author(s)
  Kawamura Y, Ishiwata T, Takizawa M, Ishida H, Asano Y, Nonoyama S.
- Journal Title
  
  Circulation Journal
  
  Volume: 74(7) Pages: 1442-50
- NAID
  10030695829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.2010
- Author(s)
  Picard C, von Bernuth H, Ghandil P, Nonoyama S, et al.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 89(6) Pages: 403-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] 成人期に診断されたCTLA4ハプロ不全による原発性免疫不全症の一例2021
- Author(s)
  關中佳奈子, 關中悠仁, 今井耕輔, 金兼弘和, 野々山恵章.
- Organizer
  第49回日本臨床免疫学会総会　ポスター発表
- Data Source
  KAKENHI-PROJECT-20H03652
[Presentation] サイトカインプロファイルが診断に有用であったマクロファージ活性化症候群を合併した川崎病の1例2020
- Author(s)
  樽谷朋晃、金井貴志、高田幸成、仁紙千尋、田村義輝、大澤麻登里、竹下誠一郎、谷内江昭宏、野々山恵章.
- Organizer
  第56回日本小児循環器学会
- Data Source
  KAKENHI-PROJECT-20K08245
[Presentation] 患者iPS細胞由来神経細胞を用いたChediak-Higashi症候群の病態解析2020
- Author(s)
  中村康子, 白石暁, 石村匡崇, 大西秀典, 堀越泰雄, 斎藤潤, 野々山恵章.
- Organizer
  第123回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03652
[Presentation] 患者iPS細胞由来神経細胞を用いたChédiak-Higashi症候群の病態解析2020
- Author(s)
  中村康子、白石暁、大西秀典、堀越泰雄、斎藤潤、野々山恵章
- Organizer
  第123回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04233
[Presentation] 原因不明の先天性疾患に対する網羅的遺伝子検査の有用性2019
- Author(s)
  松本浩, 萩原秀俊, 植松賢司, 座波清誉, 中村康子, 野々山恵章.
- Organizer
  第122回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04233
[Presentation] Trial of ulinastatin treatment for a murine model of Kawasaki Disease2018
- Author(s)
  Tsujita Yuki, Kanai Takashi, Yoichi Kawamura, Nonoyama Shigeaki, Takeshita Seiichiro
- Organizer
  The 12th International Kawasaki Disease Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 好中球細胞外トラップ(NETs)の川崎病の病態への関与2018
- Author(s)
  吉田裕輔、竹下誠一郎、川村陽一、金井貴志、辻田由喜、野々山恵章
- Organizer
  第121回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] Involvement of neutrophil extracellular traps in the pathogenesis of Kawasaki disease2018
- Author(s)
  Yoshida Yusuke, Takeshita Seiichiro, Kawamura Yoichi, Kanai Takashi, Tsujita Yuki, Nonoyama Shigeaki
- Organizer
  The 12th International Kawasaki Disease Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 好中球/リンパ球比,血小板/リンパ球比によるIVIG不応の予測に関する多施設共同研究2018
- Author(s)
  金井貴志、竹下誠一郎、川村陽一、木下恵司、中谷圭吾、岩島覚、瀧澤裕司、廣野恵一、森一越、吉田裕輔、野々山恵章
- Organizer
  第121回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] PIP3 関連分子異常による免疫不全症の病態～活性化 PI3Kδ症候群（APDS)とその類縁疾患～2018
- Author(s)
  關中佳奈子, 辻田由喜, 關中悠仁, 加藤環, 座波清誉, 今井耕輔, 野々山恵章.
- Organizer
  第1回日本免疫不全・自己炎症学会
- Data Source
  KAKENHI-PROJECT-17H04233
[Presentation] ウリナスタチン併用療法プロトコールにおける冠動脈病変合併例の予後検討2018
- Author(s)
  金井貴志、川村陽一、吉田裕輔、大澤麻登里、竹下誠一郎、野々山恵章
- Organizer
  第38回日本川崎病学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 川崎病の病態における好中球細胞外トラップ(NETs)の関与について2017
- Author(s)
  吉田裕輔、竹下誠一郎、川村陽一、金井貴志、辻田由喜、野々山恵章
- Organizer
  第37回日本川崎病学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] CAWS誘導川崎病類似マウス血管炎に対するウリナスタチンの効果について2017
- Author(s)
  辻田由喜、金井貴志、吉田裕輔、川村陽一、三浦典子、大野尚仁、野々山恵章、竹下誠一郎
- Organizer
  第37回日本川崎病学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 川崎病のIVIG不応予測因子としての好中球-リンパ球比と血小板-リンパ球比の有用性2017
- Author(s)
  川村陽一, 金井貴志, 辻田由喜, 吉田裕輔, 竹下誠一郎, 野々山恵章
- Organizer
  第120回日本小児科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2017-04-15
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 川崎病急性期のIVIG不応予測における好中球/リンパ球比、血小板/リンパ球比の有用性:他のリスクスコアとの比較2017
- Author(s)
  川村陽一、竹下誠一郎、金井貴志、辻田由喜、吉田裕輔、野々山恵章
- Organizer
  第53回日本小児循環器学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 好中球/リンパ球比、血小板/リンパ球比によるIVIG不応の予測に関する多施設共同研究2017
- Author(s)
  金井貴志、竹下誠一郎、川村陽一、木下恵司、中谷圭吾、岩島覚、瀧澤裕司、廣野恵一、森一越、吉田裕輔、野々山恵章
- Organizer
  第37回日本川崎病学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] アデノシン分解酵素の神経保護作用2017
- Author(s)
  太田宏之, 田村吏沙, 佐藤泰司, 丹生谷正史, 野々山恵章, 石塚俊晶, 西田育弘
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-16K08923
[Presentation] 川崎病のIVIG不応予測因子としての好中球-リンパ球比と血小板-リンパ球比の有用性2017
- Author(s)
  川村陽一、金井貴志、辻田由喜、吉田裕輔、竹下誠一郎、野々山恵章
- Organizer
  第120回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 川崎病急性期の好中球-リンパ球比、血小板-リンパ球比はIVIG 治療不応性の予測因子である2016
- Author(s)
  金井貴志, 川村陽一, 辻田由喜, 吉田裕輔, 竹下誠一郎, 野々山恵章
- Organizer
  第36回日本川崎病学会・学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 川崎病急性期の好中球/リンパ球比、血小板/リンパ球比はIVIG治療抵抗性の予測因子になりうるか?2016
- Author(s)
  川村陽一, 金井貴志, 辻田由喜, 吉田裕輔, 竹下誠一郎, 野々山恵章
- Organizer
  第52回日本小児循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] CAWS誘導血管炎に対するウリナスタチン投与の検討2016
- Author(s)
  辻田由喜, 金井貴志, 吉田裕輔, 川村陽一, 竹下誠一郎, 三浦典子, 大野尚仁, 野々山恵章
- Organizer
  第60回日本医真菌学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10082
[Presentation] 本邦におけるICF症候群5例の検討2014
- Author(s)
  釜江智佳子、加藤環、本間健一、小原收、今井耕輔、久保田健夫、野々山恵章
- Organizer
  日本小児科学会
- Place of Presentation
  名古屋
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-25670484
[Presentation] Classification of common variable immunodeficiency by quantification of T cell receptor recombination excision circles (TREC) and Ig kappa-deleting recombination excision circles (KREC).2012
- Author(s)
  Kamae C, Nakagawa N, Sato H, Honma K, Mitsuiki N, Ohara O, Kanegane H, Pasic S, Pan-Hammarström Q, MC van Zelm, Morio T, Imai K, Nonoyama S.
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence, Italy.
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] Clinical features and immunological abnormalities of GATA2 deficiency in JAPAN2012
- Author(s)
  Honma K, Imai K, Kamae C, Ishida H, Ito Y, Kojima S, Yokosuka T, Kanegane H, Morio T, Sasahara Y, Fujiwara T, Harigae H, Hashii Y, Ohara O, Nonoyama S
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] Classification of common variable immunodeficiency by quantification of T cell receptor recombination excision circles (TREC) and Ig kappa-deleting recombination excision circles (KREC)2012
- Author(s)
  Kamae C, Nakagawa N, Sato H, Honma K, Mitsuiki N, Ohara O, Kanegane H, Pasic S, Pan-Hammarstrom Q, MC van Zelm, Morio T, Imai K, Nonoyama S
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] 次世代シークエンサーにより、原因遺伝子の同定に至ったCVIDの1例2012
- Author(s)
  釜江智佳子、満生紀子、小原明、野口恵美子、久保田健夫、本間健一、小原收、今井耕輔、野々山恵章
- Organizer
  第3回関東甲越免疫不全症研究会
- Place of Presentation
  東京
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] Clinical features and immunological abnormalities of GATA2 deficiency in JAPAN.2012
- Author(s)
  Honma K, Imai K, Kamae C, Ishida H, Ito Y, Kojima S, Yokosuka T, Kanegane H, Morio T, Sasahara Y, Fujiwara T, Harigae H, Hashii Y, Ohara O, Nonoyama S.
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence, Italy.
- Data Source
  KAKENHI-PROJECT-22390213

1. MORIO Tomohiro (30239628)

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2. IMAI Kohsuke (90332626)

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3. OSHIMA Koichi (60525377)

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4. OHARA Osamu (20370926)

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5. MIZUTANI Shuki (60126175)

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6. TAKESHITA SEIICHIRO (50369542)

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7. KARASUYAMA Hajime (60195013)

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8. SATO Shingo (10143562)

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9. MAKI Kazushige (10311424)

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10. SORIMACHI Noriko (30217468)

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11. Ohta Hiroyuki (20535190)

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12. 長瀬隆弘 (10211442)

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13. 永田喜三郎 (10291155)

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14. 米川博通 (30142110)

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15. 北村ふじ子 (90124453)

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16. 倉持敏美 (90291153)

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17. 佐藤泰司 (10505267)

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18. 丹生谷正史 (00228256)

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19. 川村陽一 (10648801)

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20. 木下学 (70531391)

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21. 金井貴志 (70749069)

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22. 松本浩 (00536229)

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23. 大澤郁朗 (30343586)

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24. 大澤麻登里 (40792180)

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25. 關中悠仁 (90837238)

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26. WATANABE Akira

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27. MATSUMOTO Kenji

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28. SAITO Hirohisa

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29. NAKAE Susumu

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30. NARUMI Satoshi

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31. SAITOH Megumu

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32. HIRONO Keiichi

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33. 三宅紀子

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34. 高田英俊

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35. 金兼弘和

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36. 中畑龍俊

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37. 峯岸克行

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38. 關中佳奈子

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39. 長澤正之

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40. 川口裕之

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41. 森寿

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42. 小川誠司

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43. 江藤浩之

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Nonoyama Shigeaki 野々山 恵章

NONOYAMA Shigeaki 野々山 恵章

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Research to elucidate the neurodegenerative disease in Chediak Higashi syndrome caused by LYST mutationPrincipal Investigator

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Elucidation of pathogenesis and identification of novel causative gene of primary immunodeficiency due to PIP3-related molecular abnormality.Principal Investigator

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DNA double strand break repair defects and impaired immune and neuron cell differentiations in patients with EAOH caused by APTX mutation.Principal Investigator

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Identification of novel differentiation factors in immune system using iPS cells derived from primary immunodeficiencies.Principal Investigator

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Identification and functional analysis of the genes critical for B cell terminal differentiation in ICF syndrome.Principal Investigator

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自己識別機構の破綻をきたす免疫不全症の病態解明と原因遺伝子同定Principal Investigator

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Research for developing of a screening method for the congenital immunodeficiency by KREC/TREC to apply the method to the pathologic analysisPrincipal Investigator

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Nonoyama Shigeaki 野々山恵章

NONOYAMA Shigeaki 野々山恵章