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Yamagishi Shoichi  山岸 昌一

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YAMAGISHI SHO-ICHI  山岸 昌一

YAMAGISHI Shoichi  山岸 昌一

山岸 昌一  ヤマギシ ショウイチ

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Researcher Number 40281026
Other IDs
External Links
Affiliation (Current) 2025: 昭和大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 昭和大学, 医学部, 教授
2017 – 2020: 久留米大学, 医学部, 教授
2010 – 2015: 久留米大学, 医学部, 教授
2007: Kurume University, Department of Cardiovascular Medicine, Associate Professor
2006: 久留米大学, 医学部, 講師
1999: 金沢大, 医学部, 講師
1996 – 1998: 金沢大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Applied pharmacology / Pathological medical chemistry / Basic Section 42040:Laboratory animal science-related / Orthopaedic surgery
Except Principal Investigator
Basic Section 47040:Pharmacology-related / Basic Section 90140:Medical technology assessment-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 56030:Urology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 42040:Laboratory animal science-related … More / Basic Section 49030:Experimental pathology-related / Basic Section 53040:Nephrology-related / Circulatory organs internal medicine / General medical chemistry / Structural biochemistry Less
Keywords
Principal Investigator
AGE / アプタマー / 終末糖化産物 / RAGE / DNAアプタマー / 糖尿病 / 心肥大 / 動脈硬化 / マウス / ラミニン受容体 … More / PEDF / PEDF受容体 / AGEsアプタマー / GLAPアプタマー / グリセルアルデヒド由来ピリジニウム / angiogenesis / osteosarcoma / peptide / pigment epithelium-derived factor / 血管新生 / 骨肉腫 / ペプチド / 色素上皮由来因子 / 酸化ストレス / 糖尿病合併症 / 癌治療 / 終末糖化産物受容体 / 核酸医薬品 / 糖尿病合併症治療 / 血管合併症 / 腎症 / 血管障害 / AGE-アプタマー / AGEアプタマー / VEGF / 周皮細胞 / 内皮細胞 / 糖尿病性細小血管症 / トランスジェニックマウス / PAI-1 … More
Except Principal Investigator
終末糖化産物 / 動脈硬化 / RAGE / AGE / マウスモデル / DNAアプタマー / 糖尿病 / 男性不妊 / マウス / RAGEアプタマー / アプタマー / AGEs / atherosclerosis / quantitative trait locus / in situ hybridization / cyr61 / spontaneously hypertensive rat / differential display / hypertension / 手術合併症 / 食道癌 / 核酸医薬 / NEC / 壊死性腸炎 / 生活習慣 / 急性腎障害 / 敗血症 / 2型糖尿病 / 糖尿病性心筋症 / 男性不妊症 / マクロファージ / macrophage / aptamer / 血管新生・修復 / 終末糖化蛋白 / 末梢動脈疾患 / 血管内皮障害 / 糖化蛋白 / 血管石灰化 / 内皮障害 / 慢性腎臓病 / neutrophils / oxidative stress / endothelium / inflammation / 好中球 / 酸化ストレス / 血管内皮 / 炎症 / 血管平滑筋細胞 / in situハイブリダイゼーション / ディファレンシャルディスプレイ法 / 本態性高血圧症 / quantitative trait loci / spontaneously hypertinsive rat / Amino acid sequence / Purification / DNA synthesis / Pancreatic islet β-cells Less
  • Research Projects

    (20 results)
  • Research Products

    (56 results)
  • Co-Researchers

    (32 People)
  •  Mechanisms of atherosclerotic effects in exogenous advanced glycation end products(AGEs), and anti-athersclerotic actions of DNA-aptamer against AGEs

    • Principal Investigator
      寺崎 道重
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Showa University
  •  Aptamer Raised Against Receptor for Advanced Glycation End Products (RAGE) Improves Survival Rate in Septic Acute Kidney Injury Mice

    • Principal Investigator
      倉八 朋宏
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kurume University
  •  食事由来の終末糖化産物が造精機能障害を惹起する分子機序の解明と治療法の開発

    • Principal Investigator
      森 雄作
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Showa University
  •  Development of an Innovative Therapy Utilizing RAGE Aptamer to Achieve Zero Mortality in Neonatal Necrotizing Enterocolitis.

    • Principal Investigator
      古賀 義法
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kurume University
  •  Development of new biomarker for evaluation of the surgical stress for the esophageal cancer measuring AGEs

    • Principal Investigator
      山下 剛史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Showa University
  •  Effects of AGE-inhibitory DNA aptamer on male infertility

    • Principal Investigator
      Mori Yusaku
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Showa University
  •  DNA aptamer raised against advanced glycation end products as a novel therapeutic option for the prevention of diabetes-associated cardiac hypertrophy

    • Principal Investigator
      Fukui Tomoyasu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Showa University
  •  Evaluation of DNA aptamer raised against advanced glycation end products on comprehensive prevention of aging-related disordersPrincipal Investigator

    • Principal Investigator
      Yamagishi Shoichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Showa University
  •  Effects of DNA-aptamer raised against AGEs on atherosclerosis in ApoE-null mice

    • Principal Investigator
      Terasaki Michishige
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Showa University
  •  Involvements of advanced glycation end products on the developments of peripheral arterial disease in CKD patients

    • Principal Investigator
      Seiji Ueda
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Juntendo University
  •  Development of functional aptamers as a comprehensive therapeutic agent for cardiovascular diseasePrincipal Investigator

    • Principal Investigator
      YAMAGISHI SHO-ICHI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Showa University
      Kurume University
  •  Development of DNA-aptamer raised against RAGE and its clinical application for cardiovascular disease and cancerPrincipal Investigator

    • Principal Investigator
      Yamagishi Shoichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Therapeutic strategy for diabetic angiopathy using AGE aptamerPrincipal Investigator

    • Principal Investigator
      YAMAGISHI Shoichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Vascular Protective Effects of PPAR Ligands ; Anti-Polymorphonuclear Leukocyte Activity

    • Principal Investigator
      MATSUOKA Hidehiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  Potential therapeutic utility of an anti-angiogenic factor, pigment epithelium-derived factor for the treatment of osteosarcomaPrincipal Investigator

    • Principal Investigator
      YAMAGISHI Sho-ichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kurume University
  •  AGE受容体トランスジェニックマウスを用いた糖尿病性血管合併症発症機構の解明Principal Investigator

    • Principal Investigator
      山岸 昌一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  Screening for candidate genes involves in essential hypertension

    • Principal Investigator
      YONEKURA Hideto
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kanazawa University
  •  動脈硬化における内皮障害と石灰化の分子機構

    • Principal Investigator
      YAMAMOTO Hiroshi
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  後期糖化反応生成物による血管内皮細胞・周皮細胞傷害とその機構の解明Principal Investigator

    • Principal Investigator
      山岸 昌一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  インスリン産生細胞活性化因子の精製とその性質

    • Principal Investigator
      YONEKURA Hideto
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kanazawa University

All 2024 2023 2022 2020 2019 2018 2013 2011 2007 2006

All Journal Article Presentation

  • [Journal Article] SMTP-44D inhibits atherosclerotic plaque formation in apolipoprotein-E null mice partly by suppressing the AGEs-RAGE axis.2023

    • Author(s)
      Terasaki, M., Shibata, K., Mori, Y., Saito, T., Matsui, T., Ohara, M., Fukui, T., Hasumi, K., Higashimoto, Y., Nobe, K., Yamagishi, S.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 24 Issue: 7 Pages: 6505-6518

    • DOI

      10.3390/ijms24076505

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06136, KAKENHI-PROJECT-22K08318, KAKENHI-PROJECT-20K06475, KAKENHI-PROJECT-20K07075, KAKENHI-PROJECT-23K07732
  • [Journal Article] A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression2020

    • Author(s)
      Terasaki M, Yashima H, Mori Y, Saito T, Matsui T, Hiromura M, Kushima H, Osaka N, Ohara M, Fukui T, Hirano T, Yamagishi SI.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 13 Pages: 4811-4811

    • DOI

      10.3390/ijms21134811

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Journal Article] Glyceraldehyde-Derived Pyridinium Evokes Renal Tubular Cell Damage via RAGE Interaction.2020

    • Author(s)
      Ami Sotokawauchi, Nobutaka Nakamura, Takanori Matsui, Yuichiro Higashimoto, Sho-ichi Yamagishi
    • Journal Title

      Int J Mol Sci.

      Volume: 21 Issue: 7 Pages: 2604-2611

    • DOI

      10.3390/ijms21072604

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-19K06574
  • [Journal Article] ①AGE-RAGE axis stimulates oxidized LDL uptake into macrophages through cyclin-dependent kinase 5-CD36 pathway via oxidative stress generation2020

    • Author(s)
      Yashima H, Terasaki M, Sotokawauchi A, Matsui T, Mori Y, Saito T, Osaka N, Kushima H, Hiromura M, Ohara M, Fukui T, Yamagishi S-i.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 23 Pages: 9263-9263

    • DOI

      10.3390/ijms21239263

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Journal Article] Association of advanced glycation end products with sarcopenia and frailty in chronic kidney disease.2020

    • Author(s)
      Yabuuchi、J., Ueda, S., Yamagishi, S-I, Nohara, N., Nagasawa, H., Wakabayashi, K., Matsui, T., Higashimoto Y., Kadoguchi, T., Otsuka, T., Gohda, T., Suzuki, Y.
    • Journal Title

      Sci. Rep.

      Volume: 10 Issue: 1 Pages: 17647-17659

    • DOI

      10.1038/s41598-020-74673-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-19K17718, KAKENHI-PROJECT-18K08251, KAKENHI-PROJECT-18K17935
  • [Journal Article] Pathological role of advanced glycation end products (AGEs) and their receptor axis in atrial fibrillation2019

    • Author(s)
      Yamagishi Sho-ichi、Sotokawauchi Ami、Matsui Takanori
    • Journal Title

      Mini-Reviews in Medicinal Chemistry

      Volume: 19 Issue: 13 Pages: 1040-1048

    • DOI

      10.2174/1389557519666190311140737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101
  • [Journal Article] Therapeutic potential of pigment epithelium-derived factor in cancer.2019

    • Author(s)
      Yamagishi SI, Koga Y, Sotokawauchi A, Hashizume N, Fukahori S, Matsui T, Yagi M
    • Journal Title

      Curr Pharm Des.

      Volume: 印刷中 Issue: 3 Pages: 313-324

    • DOI

      10.2174/1381612825666190319112106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Fructose causes endothelial cell damage via activation of advanced glycation end products-receptor system.2019

    • Author(s)
      Sotokawauchi A, Matsui T, Higashimoto Y, Yamagishi SI.
    • Journal Title

      Diab. Vasc. Dis. Res.

      Volume: 16 Issue: 6 Pages: 556-561

    • DOI

      10.1177/1479164119866390

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-17K08968
  • [Journal Article] Concerns about clinical efficacy and safety of warfarin in diabetic patients with atrial fibrillation2019

    • Author(s)
      Yamagishi Sho-ichi
    • Journal Title

      Cardiovascular Diabetology

      Volume: 18 Issue: 1

    • DOI

      10.1186/s12933-019-0818-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Serum Levels of Protein-Bound Methylglyoxal-Derived Hydroimidazolone-1 are Independently Correlated with Asymmetric Dimethylarginine2019

    • Author(s)
      Tahara Nobuhiro、Kojima Ruchia、Yoshida Risa、Bekki Munehisa、Sugiyama Yoichi、Tahara Atsuko、Maeda Shoko、Honda Akihiro、Igata Sachiyo、Nakamura Tomohisa、Sun Jiahui、Matsui Takanori、Fukumoto Yoshihiro、Matsui Toshiro、Yamagishi Sho-Ichi
    • Journal Title

      Rejuvenation Research

      Volume: 印刷中 Issue: 5 Pages: 431-438

    • DOI

      10.1089/rej.2018.2152

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101, KAKENHI-PROJECT-17K09564
  • [Journal Article] Association of skin autofluorescence with plaque vulnerability evaluated by optical coherence tomography in patients with cardiovascular disease2018

    • Author(s)
      Fujino Yusuke、Attizzani Guilherme F.、Tahara Satoko、Wang Wei、Takagi Kensuke、Naganuma Toru、Yabushita Hiroto、Tanaka Kentaro、Sato Tomohiko、Watanabe Yusuke、Mitomo Satoru、Kurita Naoyuki、Ishiguro Hisaaki、Nakamura Shotaro、Hozawa Koji、Bezerra Hiram G.、Yamagishi Sho-ichi、Nakamura Sunao
    • Journal Title

      Atherosclerosis

      Volume: 274 Pages: 47-53

    • DOI

      10.1016/j.atherosclerosis.2018.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Role of Hyperglycemia-Induced Advanced Glycation End Product (AGE) Accumulation in Atherosclerosis2018

    • Author(s)
      Yamagishi Sho-ichi、Matsui Takanori
    • Journal Title

      Ann Vasc Dis

      Volume: 11 Issue: 3 Pages: 253-258

    • DOI

      10.3400/avd.ra.18-00070

    • NAID

      130007487741

    • ISSN
      1881-641X, 1881-6428
    • Year and Date
      2018-09-25
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101
  • [Journal Article] Therapeutic Potential of DNA-aptamers Raised Against AGE-RAGE Axis in Diabetes-related Complications2018

    • Author(s)
      Yamagishi Sho-ichi、Matsui Takanori
    • Journal Title

      Current Pharmaceutical Design

      Volume: 24 Issue: 24 Pages: 2802-2809

    • DOI

      10.2174/1381612824666180829110124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Endothelial dysfunction as a common soil of lower urinary tract symptoms and cardiovascular disease2018

    • Author(s)
      Yamagishi Sho-ichi
    • Journal Title

      International Journal of Cardiology

      Volume: 261 Pages: 209-210

    • DOI

      10.1016/j.ijcard.2018.03.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Sex disparity in cardiovascular mortality rates associated with diabetes2018

    • Author(s)
      Yamagishi Sho-ichi
    • Journal Title

      Diabetes/Metabolism Research and Reviews

      Volume: 34 Issue: 8

    • DOI

      10.1002/dmrr.3059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Clinical markers associated with glycaemic response to dipeptidyl peptidase-4 inhibitor therapy2018

    • Author(s)
      Yamagishi Sho-ichi
    • Journal Title

      Diabetes/Metabolism Research and Reviews

      Volume: 34 Issue: 7

    • DOI

      10.1002/dmrr.3024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Are Finger Skin Fluorophores Other Than Advanced Glycation End Products (AGEs) Associated With Impaired Musculoskeletal Properties?2018

    • Author(s)
      Yamagishi Sho-ichi
    • Journal Title

      The Journals of Gerontology: Series A

      Volume: 印刷中

    • DOI

      10.1093/gerona/gly280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Advanced glycation end products evoke inflammatory reactions in proximal tubular cells via autocrine production of dipeptidyl peptidase-42018

    • Author(s)
      Kaifu Kumiko、Ueda Seiji、Nakamura Nobutaka、Matsui Takanori、Yamada-Obara Nana、Ando Ryotaro、Kaida Yusuke、Nakata Masami、Matsukuma-Toyonaga Maki、Higashimoto Yuichiro、Fukami Kei、Suzuki Yusuke、Okuda Seiya、Yamagishi Sho-ichi
    • Journal Title

      Microvascular Research

      Volume: 120 Pages: 90-93

    • DOI

      10.1016/j.mvr.2018.07.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-18K08251, KAKENHI-PROJECT-16K07101, KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
  • [Journal Article] Aqueous Extract of Glucoraphanin-Rich Broccoli Sprouts Inhibits Formation of Advanced Glycation End Products and Attenuates Inflammatory Reactions in Endothelial Cells2018

    • Author(s)
      Sotokawauchi Ami、Ishibashi Yuji、Matsui Takanori、Yamagishi Sho-ichi
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2018 Issue: 1 Pages: 1-6

    • DOI

      10.1155/2018/9823141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Journal Article] Role of Ligands of Receptor for Advanced Glycation End Products (RAGE) in Peripheral Artery Disease2018

    • Author(s)
      Yamagishi Sho-ichi、Matsui Takanori
    • Journal Title

      Rejuvenation Research

      Volume: 21 Issue: 5 Pages: 456-463

    • DOI

      10.1089/rej.2017.2025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-16K07101
  • [Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy.2013

    • Author(s)
      Kaida Y,Fukami K, Matsui T,HigashimotoY,NishinoY,ObaraN,Nakayama Y, Ando R, Toyonaga M, Ueda S,TakeuchiM,InoueH,OkudaS,Yamagishi SI
    • Journal Title

      Diabetes

      Volume: 62 Issue: 9 Pages: 3241-3250

    • DOI

      10.2337/db12-1608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390111, KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007

    • Author(s)
      Yamagishi S, Matsuoka H, et. al.
    • Journal Title

      Int J Cardiol. 118

      Pages: 270-2

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] PEDF suppresses expression of receptor for advanced glycation endproducts in the eye of diabetic rats2007

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Ophthalmic Research 39(2)

      Pages: 92-7

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF blocks AGE-induced angiogenesis in vitro2007

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Hormone and Metabolic Research 39(3)

      Pages: 233-5

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007

    • Author(s)
      Yamagishi S, Matsuoka H, et. al.
    • Journal Title

      Int J Cardioi. 118(2)

      Pages: 270-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007

    • Author(s)
      Yamagishi S, Matsuoka H. et al.
    • Journal Title

      Int J Cardiol. 118

      Pages: 270-272

    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007

    • Author(s)
      Yamagishi S, Matsuoka H, et. al.
    • Journal Title

      Int J Cardiol 118

      Pages: 270-272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] PEDF inhibits angiotensin-II-induced VEGF expression in MOLT-3 T cells through its anti-oxidative properties2006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Microvascular Research 71(3)

      Pages: 222-6

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF inhibits AGE-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated VEGF expression2006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Journal of Biological Chemistry 281(29)

      Pages: 20213-20220

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF blocks angiotensisn II-induced T cell adhesion to endothelial cells by suppressing intercellular adhesion molecule-12006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Hormone and Metabolic Research 38(8)

      Pages: 546-8

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF prevents diabetes- or AGE-elicited retinal leukostasis2006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Microvascular Research 72(1-2)

      Pages: 86-90

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Presentation] 糖尿病性男性不妊症に対する終末糖化産物阻害アプタマーの有効性2024

    • Author(s)
      森 雄作、斎藤 智美、山岸 昌一
    • Organizer
      第11回日本糖尿病協会年次学術集会
    • Data Source
      KAKENHI-PROJECT-21K06582
  • [Presentation] 動脈硬化症に対する新規治療戦略:終末糖化産物を標的とした機能性核酸医薬の有効性の検討2023

    • Author(s)
      寺崎 道重, 森 雄作, 斎藤 智美, 小原 信, 福井 智康, 八島 広典, 山岸 昌一
    • Organizer
      第23回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-21K06952
  • [Presentation] 終末糖化産物アプタマーの治療応用2023

    • Author(s)
      寺崎 道重, 森 雄作, 八島 広典, 斎藤 智美, 小原 信, 福井 智康, 松井 孝憲, 山岸 昌一
    • Organizer
      第10回日本糖尿病協会年次学術集会/同時開催 IDF-WPR Congress 2023/15th Scientific Meeting of AASD
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06952
  • [Presentation] 色素上皮由来因子は,終末糖化産物(AGEs)により惹起された乳癌細胞の増殖とVEGFおよびMMP-9の発現を抑制する.2022

    • Author(s)
      松井 孝憲、靏久士保利、古賀 義法、外川内亜美、八木 実、山岸 昌一.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] 終末糖化産物(AGEs)とその受容体(RAGE)を標的とした心血管代謝老年病の包括的制御.2022

    • Author(s)
      山岸 昌一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] DNA アプタマーによる終末糖化産物受容体の阻害は老年疾患を包括的に抑制する.2022

    • Author(s)
      外川内亜美、東元祐一郎、古賀 義法、西野 友梨、松井 孝憲、山岸 昌一.
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] DNA-aptamer raised against receptor for advanced glycaion end products inhibits atherosclerosis.2022

    • Author(s)
      Terasaki M, Mori Y, Yashima H, Saito T, Sotokawauchi A, Matsui T, Hiromura M, Osaka N, Kawakami R, Shiraga Y, Ohara M, Fukui T, Yamagishi SI.
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] 終末糖化産物(AGEs)の阻害による老年病の包括的抑制.2022

    • Author(s)
      松井 孝憲、東元祐一郎、山岸 昌一.
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] DNAアプタマーを用いた終末糖化産物(AGE)および受容体(RAGE)の阻害は糖尿病合併症を包括的に抑制する.2022

    • Author(s)
      外川内亜美、東元祐一郎、松井 孝憲、山岸 昌一.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] 終末糖化産物受容体(RAGE)阻害アプタマーは動脈硬化進展を抑制する2022

    • Author(s)
      寺崎 道重、森 雄作、八島 広典、松井 孝憲、斎藤 智美、大坂 直也、広村 宗範、高畑 洋、藤川 大輝、川上 来知、白神 佳枝、外川内 亜美、小原 信、福井 智康、山岸 昌一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Presentation] DNA-aptamer raised against receptor for advanced glycation end products inhibits atherosclerosis2022

    • Author(s)
      Terasaki M, Mori Y, Yashima H, Saito T, Sotokawauchi A, Matsui T, Hiromura M, Osaka N, Kawakami R, Shiraga Y, Ohara M, Fukui T, Yamagishi SI.
    • Organizer
      第29回国際高血圧学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07075
  • [Presentation] 終末糖化産物受容体(RAGE)阻害アプタマーは動脈硬化進展を抑制する.2022

    • Author(s)
      寺崎 道重, 森 雄作, 八島 広典, 松井 孝憲, 斎藤 智美, 大坂 直也, 広村 宗範, 高畑 洋, 藤川大輝, 川上 来知, 白神 佳枝, 外川内 亜美, 小原 信, 福井 智康, 山岸 昌一.
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] 終末糖化産物受容体(RAGE)に対するDNAアプタマーは動脈硬化進展を抑制する~動脈硬化モデルマウスによる検討~.2022

    • Author(s)
      寺﨑 道重, 森 雄作, 八島 広典, 外川内 亜美, 松井 孝憲, 斎藤 智美, 広村 宗範, 大坂 直也, 藤川 大輝, 川上 来知, 白神 佳枝, 小原 信, 福井 智康, 山岸 昌一.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K06475
  • [Presentation] フルクトース由来終末糖化産物のアプタマーは、フルクトースが引き起こす内皮細胞障害を抑制する2019

    • Author(s)
      外川内亜美、松井孝憲、東元祐一郎、山岸昌一
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] 透析患者における終末糖化蛋白AGEsと心血管病、サルコペニアとの関連の解析2019

    • Author(s)
      上田誠二、藪内純子、長澤肇、大塚智之、小林敬、海部久美子、鈴木仁、合田朋仁、松井孝憲、山岸昌一、鈴木祐介
    • Organizer
      第42回 日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K08251
  • [Presentation] 透析患者の血管石灰化における終末糖化産物(AGEs)、慢性炎症の役割の解明2019

    • Author(s)
      長澤 肇、上田 誠二、薮内 純子、小林 敬、金口 泰彦、高橋 敬子、合田 朋仁、山岸 昌一、鈴木 祐介
    • Organizer
      第9回 日本腎臓リハビリテーション学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08251
  • [Presentation] Roles of chronic inflammation and AGEs in the development of vascular calcification in chronic hemodialysis patients.2019

    • Author(s)
      Otsuka T, Nagasawa H, Ueda S, Suzuki H, Yamagishi S, Suzuki Y
    • Organizer
      56th ERA-EDTA Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08251
  • [Presentation] 終末糖化産物受容体(RAGE)アプタマーは動物モデル糖尿病腎症の発症・増悪,悪性黒色腫の増殖・転移を抑制する2018

    • Author(s)
      松井孝憲, 中村信孝, 東元祐一郎, 山岸昌一
    • Organizer
      日本核酸医薬学会第4回年会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] 終末糖化産物受容体(RAGE)アプタマーはラットの糖尿病腎症の発症と進展を抑制する2018

    • Author(s)
      松井孝憲, 山岸昌一
    • Organizer
      第61回日本腎臓学会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] 終末糖化産物受容体(RAGE)阻害アプタマーは、ヌードマウスにおいて悪性メラノーマの増殖と転移を抑える2018

    • Author(s)
      外川内亜美、中村信孝、松井 孝憲、山岸 昌一
    • Organizer
      第61回日本糖尿病学会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] カナグリフロジンはヒト近位尿細管細胞におけるCarboxymethyl Lysine産生を抑制する2018

    • Author(s)
      児玉豪, 伊藤佐久耶, 甲斐田裕介, 甲斐友宝, 松井孝憲, 山岸昌一, 深水圭
    • Organizer
      第61回日本腎臓学会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] 終末糖化産物受容体(RAGE)のアプタマーは動物の糖尿病腎症の発症・増悪と悪性黒色腫の増殖・転移を阻害する2018

    • Author(s)
      松井孝憲,中村信孝, 東元祐一郎, 山岸昌一
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] Involvements of AGEs on vascular calcification in hemodialysis patients.2018

    • Author(s)
      Nagasawa H, Ueda S, Yabuuchi J, Kobayashi T, Kanaguchi Y, Takahashi K, Yamagishi S, Suzuki Y.
    • Organizer
      American Society of Nephrology (Kidney week 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08251
  • [Presentation] トホグリフロジンは尿細管保護効果により2型糖尿病マウスの腎障害を改善する2018

    • Author(s)
      松井 孝憲、石橋裕二、山岸 昌一
    • Organizer
      第61回日本糖尿病学会
    • Data Source
      KAKENHI-PROJECT-17K08968
  • [Presentation] AGEs-DNAアプタマーは糖尿病性腎症の糸球体硬化を改善する2011

    • Author(s)
      甲斐田祐介、深水圭、上田誠二、山岸昌一、奥田誠也
    • Organizer
      第54回日本腎臓病学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-22390111
  • 1.  MATSUI Takanori (10425233)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 2.  Mori Yusaku (90595919)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 3.  YONEKURA Hideto (80240373)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  広村 宗範 (00773186)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 5.  YAMAMOTO Hiroshi (00115198)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKAMURA Kazuo (90389247)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  Terasaki Michishige (90621342)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 8.  加治 建 (50315420)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  外川内 亜美 (60809177)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  古賀 義法 (70569433)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  UEDA SHIN-ICHIRO (00412502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MATSUOKA Hidehiro (80248393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  UMEI Hidekazu (90360289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAKENAKA Katsuhiko (00389248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Seiji Ueda (80322593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 16.  Fukui Tomoyasu (50384475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  那谷 耕司 (90202233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  八島 広典 (50972890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  倉八 朋宏 (80895053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  升井 大介 (90624495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  大坂 直也 (10933997)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  家入 里志 (00363359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  大西 峻 (10614638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  川野 孝文 (40457651)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  杉田 光士郎 (50781514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  武藤 充 (70404522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  中目 和彦 (70448570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  東舘 成希 (70725613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  山下 剛史 (40626818)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  大塚 耕司 (30349063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  村上 雅彦 (70255727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  東元 祐一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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