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YAMAGISHI Shoichi  山岸 昌一

ORCIDConnect your ORCID iD *help
Researcher Number 40281026
External Links
Affiliation *help 2010 – 2018 : 久留米大学, 医学部, 教授
2007 : Kurume University, Department of Cardiovascular Medicine, Associate Professor
2006 : 久留米大学, 医学部, 講師
1999 : 金沢大, 医学部, 講師
1996 – 1998 : 金沢大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Applied pharmacology / Pathological medical chemistry / Orthopaedic surgery
Except Principal Investigator
Circulatory organs internal medicine / General medical chemistry / Basic Section 53040:Nephrology-related / Structural biochemistry
Keywords
Principal Investigator
AGE / RAGE / アプタマー / osteosarcoma / 周皮細胞 / DNAアプタマー / 癌治療 / 血管合併症 / 終末糖化産物受容体 / 血管新生 … More / 核酸医薬品 / AGE-アプタマー / 腎症 / 糖尿病 / 酸化ストレス / VEGF / ラミニン受容体 / トランスジェニックマウス / 血管障害 / peptide / AGEアプタマー / 終末糖化産物 / pigment epithelium-derived factor / 糖尿病合併症 / ペプチド / PAI-1 / 内皮細胞 / 色素上皮由来因子 / 糖尿病合併症治療 / 糖尿病性細小血管症 / PEDF / angiogenesis / 骨肉腫 … More
Except Principal Investigator
differential display / hypertension / spontaneously hypertensive rat / 動脈硬化 / quantitative trait locus / cyr61 / in situ hybridization / 血管平滑筋細胞 / AGE / Amino acid sequence / 血管内皮 / ディファレンシャルディスプレイ法 / DNA synthesis / RAGE / 酸化ストレス / 本態性高血圧症 / inflammation / quantitative trait loci / 末梢動脈疾患 / atherosclerosis / 好中球 / Purification / 終末糖化蛋白 / endothelium / 慢性腎臓病 / spontaneously hypertinsive rat / in situハイブリダイゼーション / Pancreatic islet β-cells / 炎症 / 血管新生・修復 / oxidative stress / neutrophils Less
  • Research Projects

    (11results)
  • Research Products

    (12results)
  • Co-Researchers

    (13People)
  •  Involvements of advanced glycation end products on the developments of peripheral arterial disease in CKD patientsOngoing

    • Principal Investigator
      上田 誠二
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Juntendo University
  •  機能性アプタマーによる包括的心血管病の制御Principal InvestigatorOngoing

    • Principal Investigator
      山岸 昌一
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Development of DNA-aptamer raised against RAGE and its clinical application for cardiovascular disease and cancerPrincipal Investigator

    • Principal Investigator
      Yamagishi Shoichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Therapeutic strategy for diabetic angiopathy using AGE aptamerPrincipal Investigator

    • Principal Investigator
      YAMAGISHI Shoichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Kurume University
  •  Vascular Protective Effects of PPAR Ligands ; Anti-Polymorphonuclear Leukocyte Activity

    • Principal Investigator
      MATSUOKA Hidehiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kurume University
  •  Potential therapeutic utility of an anti-angiogenic factor, pigment epithelium-derived factor for the treatment of osteosarcomaPrincipal Investigator

    • Principal Investigator
      YAMAGISHI Sho-ichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kurume University
  •  AGE受容体トランスジェニックマウスを用いた糖尿病性血管合併症発症機構の解明Principal Investigator

    • Principal Investigator
      山岸 昌一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  Screening for candidate genes involves in essential hypertension

    • Principal Investigator
      YONEKURA Hideto
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kanazawa University
  •  動脈硬化における内皮障害と石灰化の分子機構

    • Principal Investigator
      YAMAMOTO Hiroshi
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  後期糖化反応生成物による血管内皮細胞・周皮細胞傷害とその機構の解明Principal Investigator

    • Principal Investigator
      山岸 昌一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kanazawa University
  •  インスリン産生細胞活性化因子の精製とその性質

    • Principal Investigator
      YONEKURA Hideto
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kanazawa University

All 2013 2011 2007 2006

All Journal Article Presentation

  • [Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy2013

    • Author(s)
      Kaida Y,Fukami K, Matsui T,HigashimotoY,NishinoY,ObaraN,Nakayama Y, Ando R, Toyonaga M, Ueda S,TakeuchiM,InoueH,OkudaS,Yamagishi SI
    • Journal Title

      Diabetes

      Volume : 62 Pages : 3241-3250

    • DOI
      10.2337/db12-1608
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390111, KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007

    • Author(s)
      Yamagishi S, Matsuoka H. et al.
    • Journal Title

      Int J Cardiol. 118

      Pages : 270-272

    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007

    • Author(s)
      Yamagishi S, Matsuoka H, et. al.
    • Journal Title

      Int J Cardiol. 118

      Pages : 270-2

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007

    • Author(s)
      Yamagishi S, Matsuoka H, et. al.
    • Journal Title

      Int J Cardioi. 118(2)

      Pages : 270-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] PEDF blocks AGE-induced angiogenesis in vitro2007

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Hormone and Metabolic Research 39(3)

      Pages : 233-5

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF suppresses expression of receptor for advanced glycation endproducts in the eye of diabetic rats2007

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Ophthalmic Research 39(2)

      Pages : 92-7

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007

    • Author(s)
      Yamagishi S, Matsuoka H, et. al.
    • Journal Title

      Int J Cardiol 118

      Pages : 270-272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590825
  • [Journal Article] PEDF blocks angiotensisn II-induced T cell adhesion to endothelial cells by suppressing intercellular adhesion molecule-12006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Hormone and Metabolic Research 38(8)

      Pages : 546-8

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF inhibits AGE-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated VEGF expression2006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Journal of Biological Chemistry 281(29)

      Pages : 20213-20220

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF prevents diabetes- or AGE-elicited retinal leukostasis2006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Microvascular Research 72(1-2)

      Pages : 86-90

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Journal Article] PEDF inhibits angiotensin-II-induced VEGF expression in MOLT-3 T cells through its anti-oxidative properties2006

    • Author(s)
      Yamagishi et al.
    • Journal Title

      Microvascular Research 71(3)

      Pages : 222-6

    • Data Source
      KAKENHI-PROJECT-18591648
  • [Presentation] AGEs-DNAアプタマーは糖尿病性腎症の糸球体硬化を改善する2011

    • Author(s)
      甲斐田祐介、深水圭、上田誠二、山岸昌一、奥田誠也
    • Organizer
      第54回日本腎臓病学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-22390111
  • 1.  YONEKURA Hideto (80240373)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 2.  YAMAMOTO Hiroshi (00115198)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 3.  NAKAMURA Kazuo (90389247)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 4.  MATSUI Takanori (10425233)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 1results
  • 5.  UEDA SHIN-ICHIRO (00412502)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 6.  MATSUOKA Hidehiro (80248393)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 4results
  • 7.  UMEI Hidekazu (90360289)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 8.  TAKENAKA Katsuhiko (00389248)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 9.  那谷 耕司 (90202233)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 10.  上田 誠二 (80322593)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 11.  HIGASHIMOTO Yuichiro
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 12.  UEDA Tadashi
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 13.  TAKEUCHI Masayoshi
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results

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