YAMAGISHI Shoichi 山岸昌一

Researcher Number	40281026
External Links
Affiliation *help	2010 – 2018 : 久留米大学, 医学部, 教授 2007 : Kurume University, Department of Cardiovascular Medicine, Associate Professor 2006 : 久留米大学, 医学部, 講師 1999 : 金沢大, 医学部, 講師 1996 – 1998 : 金沢大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Applied pharmacology / Pathological medical chemistry / Orthopaedic surgery Except Principal Investigator Circulatory organs internal medicine / General medical chemistry / Basic Section 53040:Nephrology-related / Structural biochemistry
Keywords	Principal Investigator AGE / RAGE / アプタマー / osteosarcoma / 周皮細胞 / DNAアプタマー / 癌治療 / 血管合併症 / 終末糖化産物受容体 / 血管新生 … More Except Principal Investigator differential display / hypertension / spontaneously hypertensive rat / 動脈硬化 / quantitative trait locus / cyr61 / in situ hybridization / 血管平滑筋細胞 / AGE / Amino acid sequence / 血管内皮 / ディファレンシャルディスプレイ法 / DNA synthesis / RAGE / 酸化ストレス / 本態性高血圧症 / inflammation / quantitative trait loci / 末梢動脈疾患 / atherosclerosis / 好中球 / Purification / 終末糖化蛋白 / endothelium / 慢性腎臓病 / spontaneously hypertinsive rat / in situハイブリダイゼーション / Pancreatic islet β-cells / 炎症 / 血管新生・修復 / oxidative stress / neutrophils Less

Involvements of advanced glycation end products on the developments of peripheral arterial disease in CKD patientsOngoing
- Principal Investigator
  
  上田誠二
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Juntendo University
機能性アプタマーによる包括的心血管病の制御Principal InvestigatorOngoing
- Principal Investigator
  
  山岸昌一
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kurume University
Development of DNA-aptamer raised against RAGE and its clinical application for cardiovascular disease and cancerPrincipal Investigator
- Principal Investigator
  
  Yamagishi Shoichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kurume University
Therapeutic strategy for diabetic angiopathy using AGE aptamerPrincipal Investigator
- Principal Investigator
  
  YAMAGISHI Shoichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kurume University
Vascular Protective Effects of PPAR Ligands ; Anti-Polymorphonuclear Leukocyte Activity
- Principal Investigator
  
  MATSUOKA Hidehiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kurume University
Potential therapeutic utility of an anti-angiogenic factor, pigment epithelium-derived factor for the treatment of osteosarcomaPrincipal Investigator
- Principal Investigator
  
  YAMAGISHI Sho-ichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kurume University
AGE受容体トランスジェニックマウスを用いた糖尿病性血管合併症発症機構の解明Principal Investigator
- Principal Investigator
  
  山岸昌一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Screening for candidate genes involves in essential hypertension
- Principal Investigator
  
  YONEKURA Hideto
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
動脈硬化における内皮障害と石灰化の分子機構
- Principal Investigator
  
  YAMAMOTO Hiroshi
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
後期糖化反応生成物による血管内皮細胞・周皮細胞傷害とその機構の解明Principal Investigator
- Principal Investigator
  
  山岸昌一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
インスリン産生細胞活性化因子の精製とその性質
- Principal Investigator
  
  YONEKURA Hideto
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kanazawa University

All 2013 2011 2007 2006

All Journal Article Presentation

[Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy2013
- Author(s)
  Kaida Y,Fukami K, Matsui T,HigashimotoY,NishinoY,ObaraN,Nakayama Y, Ando R, Toyonaga M, Ueda S,TakeuchiM,InoueH,OkudaS,Yamagishi SI
- Journal Title
  
  Diabetes
  
  Volume : 62 Pages : 3241-3250
- DOI
  10.2337/db12-1608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390111, KAKENHI-PROJECT-24550201, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25440056
[Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007
- Author(s)
  Yamagishi S, Matsuoka H. et al.
- Journal Title
  
  Int J Cardiol. 118
  
  Pages : 270-272
- Data Source
  KAKENHI-PROJECT-18590825
[Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007
- Author(s)
  Yamagishi S, Matsuoka H, et. al.
- Journal Title
  
  Int J Cardiol. 118
  
  Pages : 270-2
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590825
[Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007
- Author(s)
  Yamagishi S, Matsuoka H, et. al.
- Journal Title
  
  Int J Cardioi. 118(2)
  
  Pages : 270-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590825
[Journal Article] PEDF blocks AGE-induced angiogenesis in vitro2007
- Author(s)
  Yamagishi et al.
- Journal Title
  
  Hormone and Metabolic Research 39(3)
  
  Pages : 233-5
- Data Source
  KAKENHI-PROJECT-18591648
[Journal Article] PEDF suppresses expression of receptor for advanced glycation endproducts in the eye of diabetic rats2007
- Author(s)
  Yamagishi et al.
- Journal Title
  
  Ophthalmic Research 39(2)
  
  Pages : 92-7
- Data Source
  KAKENHI-PROJECT-18591648
[Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007
- Author(s)
  Yamagishi S, Matsuoka H, et. al.
- Journal Title
  
  Int J Cardiol 118
  
  Pages : 270-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590825
[Journal Article] PEDF blocks angiotensisn II-induced T cell adhesion to endothelial cells by suppressing intercellular adhesion molecule-12006
- Author(s)
  Yamagishi et al.
- Journal Title
  
  Hormone and Metabolic Research 38(8)
  
  Pages : 546-8
- Data Source
  KAKENHI-PROJECT-18591648
[Journal Article] PEDF inhibits AGE-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated VEGF expression2006
- Author(s)
  Yamagishi et al.
- Journal Title
  
  Journal of Biological Chemistry 281(29)
  
  Pages : 20213-20220
- Data Source
  KAKENHI-PROJECT-18591648
[Journal Article] PEDF prevents diabetes- or AGE-elicited retinal leukostasis2006
- Author(s)
  Yamagishi et al.
- Journal Title
  
  Microvascular Research 72(1-2)
  
  Pages : 86-90
- Data Source
  KAKENHI-PROJECT-18591648
[Journal Article] PEDF inhibits angiotensin-II-induced VEGF expression in MOLT-3 T cells through its anti-oxidative properties2006
- Author(s)
  Yamagishi et al.
- Journal Title
  
  Microvascular Research 71(3)
  
  Pages : 222-6
- Data Source
  KAKENHI-PROJECT-18591648
[Presentation] AGEs-DNAアプタマーは糖尿病性腎症の糸球体硬化を改善する2011
- Author(s)
  甲斐田祐介、深水圭、上田誠二、山岸昌一、奥田誠也
- Organizer
  第54回日本腎臓病学会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22390111

1. YONEKURA Hideto (80240373)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
2. YAMAMOTO Hiroshi (00115198)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. NAKAMURA Kazuo (90389247)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
4. MATSUI Takanori (10425233)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
5. UEDA SHIN-ICHIRO (00412502)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. MATSUOKA Hidehiro (80248393)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
7. UMEI Hidekazu (90360289)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. TAKENAKA Katsuhiko (00389248)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 那谷耕司 (90202233)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 上田誠二 (80322593)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. HIGASHIMOTO Yuichiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. UEDA Tadashi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. TAKEUCHI Masayoshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

YAMAGISHI Shoichi 山岸 昌一

Research Projects

Research Products

Co-Researchers

Involvements of advanced glycation end products on the developments of peripheral arterial disease in CKD patientsOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

機能性アプタマーによる包括的心血管病の制御Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of DNA-aptamer raised against RAGE and its clinical application for cardiovascular disease and cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic strategy for diabetic angiopathy using AGE aptamerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Vascular Protective Effects of PPAR Ligands ; Anti-Polymorphonuclear Leukocyte Activity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Potential therapeutic utility of an anti-angiogenic factor, pigment epithelium-derived factor for the treatment of osteosarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AGE受容体トランスジェニックマウスを用いた糖尿病性血管合併症発症機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening for candidate genes involves in essential hypertension

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

動脈硬化における内皮障害と石灰化の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

後期糖化反応生成物による血管内皮細胞・周皮細胞傷害とその機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

インスリン産生細胞活性化因子の精製とその性質

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome.2007

Author(s)

Journal Title

Data Source

[Journal Article] Elevated circulating oxidized LDL levels in Japanese subjects with the metabolic syndrome2007

Author(s)

YAMAGISHI Shoichi 山岸昌一