NISHIO Yoshihiko 西尾善彦

Researcher Number	40281084
Other IDs
External Links
Affiliation *help	2012 – 2013 : 鹿児島大学, 医学部, 教授 2011 – 2013 : 鹿児島大学, 医歯(薬)学総合研究科, 教授 – 2012 : 滋賀医科大学, 医学部, その他 2010 – 2011 : Shiga University of Medical Science, 医学部, 准教授 – 2011 : 鹿児島大学, 医歯学域医学系, 教授 … More
Review Section/Research Field	Principal Investigator Metabolomics / Metabolomics / 内分泌・代謝学 Except Principal Investigator Pathological medical chemistry / 内分泌・代謝学 / Metabolomics / Neurology
Keywords	Principal Investigator C / EBP / 転写因子 / 酸化ストレス / MCP-1 / 糖尿病 / インスリン抵抗性 / Insulin / インスリン / 血管平滑筋細胞 … More Except Principal Investigator SREBP-1c / mRNA differential display / RBMX / 果糖 / 転写調節 / SREBP-lc / NaィイD1+ィエD1 channel / メサンギウム細胞 / Diabetic nephropathy / 遺伝子発現 / パッチクランプ / dorsal root ganglion / 栄養素 / Nutrients / 糖尿病 / 共培養 / 代謝症候群 / gene expression / 遺伝子発現調節 / 終末糖化産物(AGE) / 痛覚 / Fructose / tetrodotoxin-resistant / インスリン抵抗性 / 果糖反応性遺伝子 / hyperalgesia / Advanced glycation end products(AGE) / 糖尿病性腎症 / TTX抵抗性 / Naチャネル / 後根神経節細胞 / neuropathy / 肝細胞 / diabetes melliitus / 肝インスリン抵抗性 / 膜電位固定 / TLR4 / NASH / Mesangial cells Less

The significance of activation of macrophage in the development of nonalcoholic steatohepatitis
- Principal Investigator
  
  NAGAI Yoshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  St. Marianna University School of Medicine
The effects of omega-3 PUFA on vascular functionPrincipal Investigator
- Principal Investigator
  
  NISHIO Yoshihiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kagoshima University
Identification and characterization of a new factor regulating SREBP-1c gene in liver.Principal Investigator
- Principal Investigator
  
  NISHIO Yoshihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
Elucidation of the mechanism for the activation of transcription factors and gene response in the aorta of the Postprandial state of rataPrincipal Investigator
- Principal Investigator
  
  NISHIO Yoshihiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
Elucidation of the mechanism for the activation of transcription factors and gene response in the aorta of the postprandial state ofrata
- Principal Investigator
  
  KASHIWAGI Atsunori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
Identification of the inhibitory factor for the transcription of inflammatory genes in vascular smooth muscle cellsPrincipal Investigator
- Principal Investigator
  
  NISHIO Yoshihiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
A novel effect of insulin on vascular smooth muscle cells through the transcriptional regulation ?the meaning of the activation of C/EBPPrincipal Investigator
- Principal Investigator
  
  NISHIO Yoshihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
Identification of oxidative stress related genes and transcription factors in vascular tissuesPrincipal Investigator
- Principal Investigator
  
  NISHIO Yoshihiko
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Shiga University of Medical Science
糖尿病心血管組織における酸化ストレス亢進の分子機構と遺伝子発現異常誘導機構の同定Principal Investigator
- Principal Investigator
  
  西尾善彦
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Shiga University of Medical Science
Cross-link of signal transduction and channel function diabetic neuropathy
- Principal Investigator
  
  YASUDA Hitoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Shiga University of Medical Science
糖尿病における酸化ストレス関連遺伝子発現異常の同定とその臨床的意義Principal Investigator
- Principal Investigator
  
  西尾善彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Shiga University of Medical Science
IDENTIFICATION OF GENES REGULATED BY ADVANCED GLYCATION END PRODUCTS IN CULTURED GLOMERULAR MESANGIAL CELLS
- Principal Investigator
  
  HANEDA Masakazu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  SHIGA UNIVERSITY OF MEDICAL SCIENCE

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Mitochondorial Pathogenesis2004
- Author(s)
  Nishio Y et al.
- Total Pages
  352
- Publisher
  The New York Academy of Sciences
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] 4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs2014
- Author(s)
  Nakagawa F, Morino K, Ugi S, Ishikado A, Kondo K, Sato D, Konno S, Nemoto K, Kusunoki C, Sekine O, Sunagawa A, Kawamura M, Inoue N, Nishio Y, Maegawa H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 443(3) Pages : 991-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] A fish-based diet intervention improves endothelial function in postmenopausal women with type 2 diabetes mellitus : A randomized crossover trial2014
- Author(s)
  Kondo K, Morino K, Nishio Y, Kondo M, Nakao K, Nakagawa F, Ishikado A, Sekine O, Yoshizaki T, Kashiwagi A, Ugi S, Maegawa H
- Journal Title
  
  Metabolism
  
  Volume : (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] 4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation.2013
- Author(s)
  Ishikado A, Morino K, Nishio Y, Nakagawa F, Mukose A, Sono Y, Yoshioka N, Kondo K, Sekine O, Yoshizaki T, Ugi S, Uzu T, Kawai H, Makino T, Okamura T, Yamamoto M, Kashiwagi A, Maegawa H
- Journal Title
  
  PLoS One
  
  Volume : 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] 4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs.2013
- Author(s)
  Nakagawa F, Morino K, Ugi S, Ishikado A, Kondo K, Sato D, Konno S, Nemoto K, Kusunoki C, Sekine O, Sunagawa A, Kawamura M, Inoue N, Nishio Y, Maegawa H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 443 Pages : 991-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes2013
- Author(s)
  Kusunoki C, Yang L, Yoshizaki T, Nakagawa F, Ishikado A, Kondo M, Morino K, Sekine O, Ugi S, Nishio Y, Kashiwagi A, Maegawa H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 430 Pages : 225-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Intraepidermal nerve fiber density and nerve conduction study parameters correlate with clinical staging of diabetic polyneuropathy2013
- Author(s)
  Arimura A, Deguchi T, Sugimoto K, Uto T, Nakamura T, Arimura Y, Arimura K, Yagihashi S, Nishio Y, Takashima H
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume : 99 Pages : 24-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes2013
- Author(s)
  Kusunoki C, Yang L, Yoshizaki T, Nakagawa F, Ishikado A, Kondo M, Morino K, Sekine O, Ugi S, Nishio Y, Kashiwagi A, Maegawa H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 430(1) Pages : 225-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet2013
- Author(s)
  Ushio M, Nishio Y, Sekine O, Nagai Y, Maeno Y, Ugi S, Yoshizaki T, Morino K, Kume S, Kashiwagi A, Maegawa H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume : 305(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] 4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation2013
- Author(s)
  Ishikado A, Morino K, Nishio Y, Nakagawa F, Mukose A, Sono Y, Yoshioka N, Kondo K, Sekine O, Yoshizaki T, Ugi S, Uzu T, Kawai H, Makino T, Okamura T, Yamamoto M, Kashiwagi A, Maegawa H
- Journal Title
  
  PLoS One
  
  Volume : 8(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States2013
- Author(s)
  Azuma K, Curb JD, Kadowaki T, Edmundowicz D, Kadowaki S, Masaki KH, El-Saed A, Nishio Y, Seto TB, Okamura T, Cetinel C, Kadota A, Sutton-Tyrrell K, Miura K, Evans RW, Takamiya T, Maegawa H, Miljkovic I, Kuller LH, Ueshima H, Kelley DE, Sekikawa A
- Journal Title
  
  Obes Res Clin Pract
  
  Volume : 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet.2013
- Author(s)
  Ushio M, Nishio Y, Sekine O, Nagai Y, Maeno Y, Ugi S, Yoshizaki T, Morino K, Kume S, Kashiwagi A, Maegawa H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume : 305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j32012
- Author(s)
  Yamamoto H, Morino K, Nishio Y, Ugi S, Yoshizaki T, Kashiwagi A, Maegawa H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume : 303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Japanese Elderly Intervention Trial Research Group. Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: sub-analysis of the Japanese Elderly Diabetes Intervention Trial2012
- Author(s)
  Araki S, Nishio Y, Araki A, Umegaki H, Sakurai T, Iimuro S, Ohashi Y, Uzu T, Maegawa H, Kashiwagi A, Ito H
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume : Suppl 1 Pages : 127-133
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Autophagy regulates inflammation in adipocytes2012
- Author(s)
  Yoshizaki T, Kusunoki C, Kondo M, Yasuda M, Kume S, Morino K, Sekine O, Ugi S, Uzu T, Nishio Y, Kashiwagi A, Maegawa H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 417 Pages : 352-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j32012
- Author(s)
  Yamamoto H, Morino K, Nishio Y, Ugi S, Yoshizaki T, Kashiwagi A, Maegawa H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume : 303(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Differential association of docosahexaenoic and eicosapentaenoic acids with carotid intima-media thickness.2011
- Author(s)
  Sekikawa A, Kadowaki T, El-Saed A, Okamura T, Sutton-Tyrrell K, Nakamura Y, Evans RW, Mitsunami K, Edmundowicz D, Nishio Y, et al
- Journal Title
  
  Stroke
  
  Volume : 42 Pages : 2538-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Postprandial activation of protein kinase Cm regulates the expression of adipocytokines via the transcription factor AP-2b.2011
- Author(s)
  Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H.
- Journal Title
  
  Int J Mol Med.PubMed 28(1)
  
  Pages : 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Association between serum soluble TNFα receptors and renal dysfunction in type 2 diabetic patients without proteinuria.2011
- Author(s)
  Miyazawa I, Araki S, Obata T, Yoshizaki T, Morino K, Kadota A, Ugi S, Kawai H, Uzu T, Nishio Y, Koya D, Haneda M, Kashiwagi A, Maegawa H.
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume : 92 Pages : 174-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] GW501516, a PPARδ agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFκB pathway in mice.2011
- Author(s)
  Yang X, Kume S, Tanaka Y, Isshiki K, Araki S, Chin-Kanasaki M, Sugimoto T, Koya D, Haneda M, Sugaya T, Li D, Han P, Nishio Y, Kashiwagi A, Maegawa H, Uzu T
- Journal Title
  
  PLoS One
  
  Volume : 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Postprandial activation of protein kinase Cμ regulates the expression of adipocytokines via the transcription factor AP-2β.2011
- Author(s)
  Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H
- Journal Title
  
  Int J Mol Med
  
  Volume : 28 Pages : 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591336
[Journal Article] Postprandial activation of protein kinase Cツオ regulates the expression of adipocytokines via the transcription factor AP-2beta2011
- Author(s)
  Kondo M, Ugi S, Morino K, Fuke T, Obata T, Yoshizaki2T, Nishio Y, Maeda S, Kashiwagi A, Maegawa H
- Journal Title
  
  Int J Mol Med
  
  Volume : 28 Pages : 95-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Transcription factor AP-2beta : a negative regulator of IRS-1 gene expression.2010
- Author(s)
  Meng X, Kondo M, Morino K, Fuke T, Obata T, Yoshizaki T, Ugi S, Nishio Y, Maeda S, Araki E, Kashiwagi A, Maegawa H.
- Journal Title
  
  Biochem Biophys Res Commun. 19;392(4)
  
  Pages : 526-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Relation of the expression of transcriptional factor TFAP2B to that of adipokines in subcutaneous and omental adipose tissues.2010
- Author(s)
  Ugi S, Nishio Y, Yamamoto H, Ikeda K, Kobayashi M, Tsukada S, Kondo M, Morino K, Obata T, Yoshizaki T, Uzu T, Naitoh H, Tani T, Maeda S, Kashiwagi A, Maegawa H.
- Journal Title
  
  Obesity (Silver Spring). 18(7)
  
  Pages : 1277-1282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells.2010
- Author(s)
  Ishikado A, Nishio Y, Morino K, Ugi S, Kondo H, Makino T, Kashiwagi A, Maegawa H.
- Journal Title
  
  Biochem Biophys Res Commun. 5;402(1)
  
  Pages : 99-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells2010
- Author(s)
  Ishikado A, Nishio Y, Morino K, Ugi S, Kondo H, Makino T, Kashiwagi A, Maegawa H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 402 Pages : 99-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Effects of a Fish-Based Diet on the Serum Adiponectin Concentration in Young, Non-Obese, Healthy Japanese Subjects2010
- Author(s)
  Kondo K, Morino K, Nishio Y, Kondo M, Fuke T, Ugi S, Iwakawa H, Kashiwagi A, Maegawa H.
- Journal Title
  
  J Atheroscler Thromb (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Membrane localization of protein-tyrosine phosphatase 1B is essential for its activation of sterol regulatory element-binding protein-1 gene expression and consequent hypertriglyceridaemia.2009
- Author(s)
  Ugi S, Shi K, Nishio Y, Shimizu S, Guo B, Sekine O, Ikeda K, Egawa K, Yoshizaki T, Nagai Y, Koya D, Takada T, Torii R, Kimura H, Kashiwagi A, MaegawaH.
- Journal Title
  
  J Biochem. 146(4)
  
  Pages : 541-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells.2009
- Author(s)
  Ishikado A, Nishio Y, Yamane K, Mukose A, Morino K, Murakami Y, Sekine O, Makino T, Maegawa H, Kashiwagi A.
- Journal Title
  
  Atherosclerosis. 205(2)
  
  Pages : 404-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.2009
- Author(s)
  Omura Y, Nishio Y, Takemoto T, Ikeuchi C, Sekine O, Morino K, Maeno Y, Obata T, Ugi S, Maegawa H, Kimura H, Kashiwagi A.
- Journal Title
  
  BMB Rep. 30;42(4)
  
  Pages : 232-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Transcription factor activating protein-2beta : a positive regulator of monocyte chemoattractant protein-1 gene expression.2009
- Author(s)
  Kondo M, Maegawa H, Obata T, Ugi S, Ikeda K, Morino K, Nakai Y, Nishio Y, Maeda S, Kashiwagi A.
- Journal Title
  
  Endocrinology. 150(4)
  
  Pages : 1654-1661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Higher liver fat content among Japanese in Japan compared with non-Hispanic whites in the United States2009
- Author(s)
  Azuma K, Kadowaki T, Cetinel C, Kadota A, El-Saed A, Kadowaki S, Edmundowicz D, Nishio Y, Sutton-Tyrrell K, Okamura T, Evans RW, Takamiya T, Ueshima H, Curb JD, Abbott RD, Kuller LH, Kelley DE, Sekikawa A; ERA JUMP study group
- Journal Title
  
  Metabolism 58
  
  Pages : 1200-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Transcription factor activating protein-2beta : a positive regulator of monocyte chemoattractant protein-1 gene expression2009
- Author(s)
  Kondo M, Maegawa H, Obata T, Ugi S, Ikeda K, Morino K, Nakai Y, Nishio Y, Maeda S, Kashiwagi A
- Journal Title
  
  Endocrinology 150
  
  Pages : 1654-1661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Membrane localization of protein-tyrosine phosphatase 1B is essential for its activation of sterol regulatory element-binding protein-1 gene expression and consequent hypertriglyceridaemia2009
- Author(s)
  Ugi S, Shi K, Nishio Y, Shimizu S, Guo B, Sekine O, Ikeda K, Egawa K, Yoshizaki T, Nagai Y, Koya D, Takada T, Torii R, Kimura H, Kashiwagi A, Maegawa H.
- Journal Title
  
  J Biochem 146
  
  Pages : 541-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and -delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats.2007
- Author(s)
  Sato Y, Nishio Y, Sekine O et al.
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and -delta andmonocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats.2007
- Author(s)
  Sato Y, Nishio Y, Sekine O, 他
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] Pitavastatin restores vascular dysfunction in insulin-resistant state byinhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxidesynthase-dependent superoxide production.2007
- Author(s)
  Shinozaki K, Nishio Y, Ayajiki K, 他
- Journal Title
  
  J Cardiovasc Pharmacol 49
  
  Pages : 122-130
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-lc gene response tohigh-fructose diet.2007
- Author(s)
  Takemoto T, Nishio Y, Sekine O, 他
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and-delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats.2007
- Author(s)
  Sato Y, Nishio Y, Sekine O et al.
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-9
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] Pitavastatin restores vascular dysfunction in insulin-resistant state byinhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxidesynthase-dependent superoxide production2007
- Author(s)
  Shinozaki, K., Nishio, Y., Ayajiki, K., et. al.
- Journal Title
  
  J Cardiovasc Pharmacol 49
  
  Pages : 122-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response tohigh-fructose diet2007
- Author(s)
  Takemoto, T., Nishio, Y., Sekine, O., et. al.
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and -delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rat2007
- Author(s)
  Sato, Y., Nishio, Y., Sekine, O., et. al.
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response tohigh-fiuctose diet2007
- Author(s)
  Takemoto T, Nishio Y, Sekine O, 他
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] Pitavastatin restores vascular dysfunction in insulin-resistant state byinhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxidesynthase-dependent superoxide production2007
- Author(s)
  Shinozaki K, Nishio Y, Ayajiki K, 他
- Journal Title
  
  J Cardiovasc Pharmacol 49
  
  Pages : 122-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and-delta an dmonocyte chemoarnactant protein-1 genes in aortas from hyperinsulinaemicrats2007
- Author(s)
  Sato Y, Nishio Y, Sekine O, 他
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-I c gene response tohigh-fructose diet2007
- Author(s)
  Takemoto, T., Nishio, Y., Sekine, O., et. al.
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and -delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rat2007
- Author(s)
  Sato, Y., Nishio, Y., Sekine, O., et. al.
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response tohigh-fructose diet.2007
- Author(s)
  Takemoto T, Nishio Y, Sekine O, 他
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and-delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats.2007
- Author(s)
  Sato Y, Nishio Y, Sekine O, 他
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] Increased expression of CCAAT/enhancer binding protein-beta and-delta andmonocyte chemoattractant protein-1 genes in aortas from hyperinsulinae mic rats.2007
- Author(s)
  Sato Y, Nishio Y, SekineO, 他
- Journal Title
  
  Diabetologia 50
  
  Pages : 481-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-lc gene response tohigh-fructose diet.2007
- Author(s)
  Takemoto T, Nishio Y, SekineO, 他
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet.2006
- Author(s)
  Takemoto T, Nishio Y, Sekine O, et al.
- Journal Title
  
  FEBS Lett 581
  
  Pages : 218-222
- Data Source
  KAKENHI-PROJECT-17390262
[Journal Article] RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet.2006
- Author(s)
  Takemoto T, Nishio Y, Sekine O, et al.
- Journal Title
  
  FEBS Lett. 581
  
  Pages : 218-22
- Data Source
  KAKENHI-PROJECT-18590981
[Journal Article] The Transcription Factor AP-2{beta}Causes Cell Enlargement and insulin Resistance in 3T3-L1 Adipocytes.2006
- Author(s)
  Tao Y, Maegawa H, Ugi S, Ikeda K, Nagai Y, Egawa K, Nakamura T, Tsukada S, Nishio Y, Maeda S, Kashiwagi A
- Journal Title
  
  Endocrinology 147
  
  Pages : 1685-96
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] The Transcription Factor AP-2 {beta} Causes Cell Enlargement and Insulin Resistance in 3T3-L1 Adipocytes.2006
- Author(s)
  Tao Y, Maegawa H, Ugi S, Ikeda K, Nagai Y, Egawa K, Nakamura T, Tsukada S, Nishio Y, Maeda S, Kashiwagi A
- Journal Title
  
  Endocrinology 147
  
  Pages : 1685-1696
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] The Transcription Factor AP-2{beta} Causes Cell Enlargement and Insulin Resistance in 3T3-L1 Adipocytes.2006
- Author(s)
  Tao Y, Maegawa H, Ugi S, Ikeda K, Nagai Y, Egawa K, Nakamura T, Tsukada S, Nishio Y, Maeda S, Kashiwagi A
- Journal Title
  
  Endocrinology 147
  
  Pages : 1685-1696
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] Bidirectional regulation of monocyte chemoattractant protein-1 gene at distinctsites of its promoter by nitric oxide in vascular smooth muscle cells2005
- Author(s)
  Kodama K, Nishio Y, Sekine O, Sato Y, Egawa K, Maegawa H, Kashiwagi A
- Journal Title
  
  Am J Physiol Cell Physiol 289
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] Bidirectional regulation of monocyte chemoattractant protein-1 gene at distinctsites of its promoter by nitric oxide in vascular smooth muscle cells2005
- Author(s)
  Kodama K, Nishio Y, Sekine O, Sato Y, Egawa K, Maegawa H, Kashiwagi A
- Journal Title
  
  Am J Physiol Cell Physiol 289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] Supplement oftetrahydrobiopterin by a gene transfer of GTP cyclohydrolase IcDNA improves vascular dysfunction in insulin-resistant rats.2005
- Author(s)
  Shinozaki K, Nishio Y, Yoshida Y, Koya D, Ayajiki K, Masada M, Kashiwagi A, Okamura T
- Journal Title
  
  J Cardiovasc Pharmacol 46
  
  Pages : 505-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] Bidirectional regulation of monocyte chemoattractant protein-1 gene at distinctsites of its promoter by nitric oxide in vascular smooth muscle cells2005
- Author(s)
  Kodama K, Nishio Y, Sekine 0, Sato Y, Egawa K, Maegawa H, Kashiwagi A
- Journal Title
  
  Am J Physiol Cell Physiol 289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] Supplement of tetrahydrobiopterin by a gene transfer of GTP cyclohydrolase IcDNA improves vascular dysfunction in insulin-resistant rats.2005
- Author(s)
  Shinozaki K, Nishio Y, Yoshida Y, Koya D, Ayajiki K, Masada M, Kashiwagi A, Okamura T
- Journal Title
  
  J Cardiovasc Pharmacol 46
  
  Pages : 505-512
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] Single nucleotide polymorphism (-468 Gly to A) at the promoter region of SREBP-1c associates with genetic defect of fructose-induced hepatic lipogenesis2004
- Author(s)
  Nagata R, Nishio Y et al.
- Journal Title
  
  J Biol Chem 279・28
  
  Pages : 29031-29042
- Data Source
  KAKENHI-PROJECT-16590877
[Journal Article] SAFB1, an RBMX-Binding Protein, is a Newly Identified Regulator of Hepatic SREBP-lc Gene
- Author(s)
  Omura Y, Nishio Y, Takemoto T, Ikeuchi C, Sekine O, Maeno Y, Obata T, Ugi S, Maegawa H, Kimura H, Kashiwagi A
- Journal Title
  
  BMB reports (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] The effects of omega-3 PUFA on vascular function2013
- Author(s)
  西尾善彦
- Organizer
  第56回日本糖尿病学会Symposium 15 (Diabetes and Macrovascular Complications)
- Place of Presentation
  熊本
- Year and Date
  2013-05-18
- Data Source
  KAKENHI-PROJECT-23591336
[Presentation] 血管内皮細胞機能改善をめざした治療戦略2013
- Author(s)
  西尾善彦
- Organizer
  第23回日本糖尿病合併症学会シンポジウム3
- Place of Presentation
  旭川
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23591336
[Presentation] A high-fiber diet improves M1/M2 phenotype as well as the vascular function in the patients with type 2 diabetes mellitus2012
- Author(s)
  Keiko Kondo, Yoshihiko Nishio, Atsushi Ishikado et al.
- Organizer
  72nd scientific sessions of American diabetes association
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-23591336
[Presentation] 多価不飽和脂肪酸による血管内皮での酸化ストレス抑制作用2011
- Author(s)
  西尾善彦、石角篤、柏木厚典、前川聡
- Organizer
  第４３回日本動脈硬化学会(招待講演)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591336
[Presentation] HA Increases HO-1 Expression and Antioxidative Activity through the Activation of Nrf2 in Vascular Endothelial Cells.2011
- Author(s)
  Atsushi Ishikado, Yoshihiko Nishio, Katsutaro Morino, Atsushi Mukose, Satoshi Ugi, Hajime Kondo, Yoko Murakami, Taketoshi Makino, Atsunori Kashiwagi, Hiroshi Maegawa
- Organizer
  71st Scientific Sessions-American Diabetes Association
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23591336
[Presentation] Hyperinsulinemia and atheroscrelosis2010
- Author(s)
  西尾善彦, 石角篤、前川聡
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] N-3 polyunsaturated fatty acid (n-3 PUFA) increases anti-oxidant enzyme HO-1 and decreases inflammatory cytokine MCP-1 in vascular endothelial cells.2010
- Author(s)
  Ishikado A, Nishio Y, Morino K, Mukose K, Murakami Y, Makino T, Kashiwagi A, Maegawa H
- Organizer
  70th annual meeting of American Diabetes Association
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] RNA binding motif protein on the X chromosome (RBMX), a novel key molecule for developing metabolic syndrome and NASH.2009
- Author(s)
  Maeno Y, Nishio Y, Nagai Y, Takemoto T, Sekine O, Omura Y, Ushio M, Kimura H, Kashiwagi A, Maegawa H
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] フルクトースによる脂質合成促進の分子機構2009
- Author(s)
  西尾善彦, 前川聡, 柏木厚典
- Organizer
  第12回日本病態栄養学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] 糖尿病合併症の発症機構と歯周病との関連について2009
- Author(s)
  西尾善彦, 前川聡, 柏木厚典
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] 高インスリン血症と血管炎症における転写因子の役割2009
- Author(s)
  西尾善彦, 前川聡, 柏木厚典
- Organizer
  第24回日本糖尿病合併症学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] A Newly Identified Protein, LOC673353, Activates the Promoter of SREBP-1c Gene through Direct Binding to Its Promoter and Association with a Co-Activator, RBMX.2008
- Author(s)
  Sekine O, Nishio Y, Ikeuchi C, Takemoto T, Quynh N, Ugi S, Maegawa H, Kimura H, Kashiwagi A
- Organizer
  68th annual meeting of American Diabetes Association
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] Safb1, an RBMX-Binding Protein, is a Newly Identified Activator in the Regulation of Hepatic SREBP-1 Gene Expression.2008
- Author(s)
  Omura Y, Nishio Y, Takemoto T, Ikeuchi C, Sekine O, Morino K, Maeno Y, Obata T, Ugi S, Maegawa H, Kimura H, Kashiwagi A
- Organizer
  68th annual meeting of American Diabetes Association
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] Activation of Transcription Factor AP-2β Mediated by Protein Kinase C μ Aggravates Expression of Inflammatory Adipokines in Differentiated Adipocyte.2008
- Author(s)
  Kondo M, Maegawa H, Morino K, Fuke T, Obata T, Ugi S, Nishio Y, Maeda S, Kashiwagi A
- Organizer
  68th annual meeting of American Diabetes Association
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] 果糖反応性SREBP-1c遺伝子発現に関する新しい転写調節因子群の同定2008
- Author(s)
  西尾善彦, 前川聡, 柏木厚典
- Organizer
  第29回日本肥満学会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] The molecular mechanism of atherosclerosis induced by hyperinsulinemia2008
- Author(s)
  西尾善彦, 前川聡, 柏木厚典
- Organizer
  第40回日本動脈硬化学会総会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-20591058
[Presentation] 2型糖尿病と動脈硬化2007
- Author(s)
  西尾善彦
- Organizer
  第22回日本糖尿病合併症学会(シンポジウム)
- Place of Presentation
  筑波
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590981
[Presentation] Increased Expression of CCAAT/Enhancer Binding Protein-β and -δ and Monocyte Chemoattractant Protein-1 Genes in Aortas from Hyperinsulinemic Rats2006
- Author(s)
  Sekine, O., Nishio, Y., Sato, Y., et. al.
- Organizer
  66th Scientific Sessions of American Diabetes Association
- Place of Presentation
  San Francisco, CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590981
[Presentation] 高インスリン血症と血管炎症2006
- Author(s)
  西尾善彦
- Organizer
  第21回日本糖尿病合併症学会(シンポジウム)
- Place of Presentation
  弘前
- Year and Date
  2006-10-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590981
[Presentation] Increased Expression of CCAAT/Enhancer Binding Protein-β and-δ and Monocyte Chemoattractant Protein-1 Genes in Aortas from Hyperinsulinemic Rats.2006
- Author(s)
  Sekine O, Nishio Y, Sato Y, 他
- Organizer
  66th Scientific Sessions of American Diabetes Association
- Place of Presentation
  San Francisco, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390262
[Presentation] A Newly Identifi ed RNA Binding Motif Protein Controls Transcription of SREBP-lc Gene in the Liver of High-Fructose Fed Mice2006
- Author(s)
  Ikeuchi, C., Nishio, Y., Sekine, O., et. al.
- Organizer
  66th Scientific Sessions of American Diabetes Association
- Place of Presentation
  San Francisco, CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390262
[Presentation] Increased Expression of CCAAT/Enhancer Binding Protein-8 and -8 and Monocyte Chemoattractant Protein-I Genes in Aortas from Hyperinsulinemic Rats2006
- Author(s)
  Sekine, O., Nishio, Y., Sato, Y., et. al.
- Organizer
  66th Scientific Sessions of American Diabetes Association
- Place of Presentation
  San Francisco, CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390262
[Presentation] A Newly Identified RNA Binding Motif Protein Controls Transcription of SREBP-1c Gene in the Liver of High-Fructose Fed Mice.2006
- Author(s)
  Ikeuchi C, Nishio Y, Sekine O, 他
- Organizer
  66th Scientific Sessions of American Diabetes Association
- Place of Presentation
  San Francisco, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390262
[Presentation] ω３不飽和脂肪酸による抗酸化治療
- Author(s)
  西尾善彦、石角篤、前川聡、柏木厚典
- Organizer
  第２７回日本糖尿病合併症学会　シンポジウム４
- Place of Presentation
  福岡市
- Invited
- Data Source
  KAKENHI-PROJECT-23591336

1. NAGAI Yoshio (90402718)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
2. YOSHIZAKI Takeshi (20510324)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. HANEDA Masakazu (60164894)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. YASUDA Hitoshi (80135467)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. TERADA Masahiko (00227521)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. KITASATO Hiroshi (20079700)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. KASHIWAGI Atsunori (20127210)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. MAEGAWA Hiroshi (00209363)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. MAEDA Shiro (50314159)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

NISHIO Yoshihiko 西尾 善彦

Research Projects

Research Products

Co-Researchers

The significance of activation of macrophage in the development of nonalcoholic steatohepatitis

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The effects of omega-3 PUFA on vascular functionPrincipal Investigator

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Identification and characterization of a new factor regulating SREBP-1c gene in liver.Principal Investigator

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Elucidation of the mechanism for the activation of transcription factors and gene response in the aorta of the Postprandial state of rataPrincipal Investigator

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Elucidation of the mechanism for the activation of transcription factors and gene response in the aorta of the postprandial state ofrata

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Identification of the inhibitory factor for the transcription of inflammatory genes in vascular smooth muscle cellsPrincipal Investigator

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A novel effect of insulin on vascular smooth muscle cells through the transcriptional regulation ?the meaning of the activation of C/EBPPrincipal Investigator

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Identification of oxidative stress related genes and transcription factors in vascular tissuesPrincipal Investigator

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糖尿病心血管組織における酸化ストレス亢進の分子機構と遺伝子発現異常誘導機構の同定Principal Investigator

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Cross-link of signal transduction and channel function diabetic neuropathy

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糖尿病における酸化ストレス関連遺伝子発現異常の同定とその臨床的意義Principal Investigator

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IDENTIFICATION OF GENES REGULATED BY ADVANCED GLYCATION END PRODUCTS IN CULTURED GLOMERULAR MESANGIAL CELLS

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[Book] Mitochondorial Pathogenesis2004

Author(s)

Total Pages

Publisher

NISHIO Yoshihiko 西尾善彦