Shimoda Kei 下田恵

… Alternative Names

SHIMODA Kei 下田恵

下田恵シモダケイ

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Researcher Number	40284153
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 大分大学, 医学部, 准教授 2007 – 2018: Oita University, 医学部, 准教授 2003 – 2005: 大分大学, 医学部, 助教授 2002: 大分医科大学, 医学部, 助教授 1997 – 1999: 広島大学, 理学部, 助手
Review Section/Research Field	Principal Investigator Chemical pharmacy / Basic Section 90120:Biomaterials-related / Biomedical engineering/Biomaterial science and engineering / Bioorganic chemistry Except Principal Investigator Bioorganic chemistry / Basic Section 90120:Biomaterials-related / Bio-related chemistry
Keywords	Principal Investigator DDS / バイオナノカプセル / 酵素 / シアル酸 / オリゴサッカライド / 配糖体 / 合成化学 / 配糖体プロドラッグ / プロドラッグ / 生物変換 … More / 酵素化学 / 薬理学 / ドラッグデリバリーシステム / 肝細胞癌 / 薬物送達システム / DDS製剤 / タキソール誘導体 / 生体触媒 / 有機合成 / 合成 / 誘導体 / タキソール / 酵素反応 / タンパク質 / 有機化学 / バイオテクノロジー / 有機合成化学 / 連続運転 / クマリン系医薬品 / ステロイド系医薬品 / スラリー型リアクター / 低副作用医薬品 / 効率的配糖体生産 / 膜型酵素バイオリアクター / 配糖化酵素 / ステロイドホルモン / フラボノイド類 / 光学活性医薬品 … More Except Principal Investigator Signal transduction / シグナル伝達 / アポトーシス / モノテルペノイド / 新規技術 / グルコース / 酵素化学 / ヒスタミン遊離抑制 / 糖転移酵素 / 酵素変換 / Eliciter / Chemical Stress / Active Oxygen / Monoterpenoids / Apoptosis / Plant / ユリシター / シゲナル伝達 / エリシター / ストレス / 活性酸素 / 植物 / Secreted enzyme / Defense reaction / Cultured plant cells / apoptosis / Recognition of chemical stress / Monoterpenoid / ゼニゴケ培養細胞 / ストレス分子認識 / 分泌酵素 / 生体防御 / 植物培養細胞 / 化学ストレス Less

脳へ移行するグルコースの特性から着想を得た、脳へ薬物を輸送する新技術の開発
- Principal Investigator
  
  桐明祐弥
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  St. Mary's College
Development of blood-brain barrier-penetrating oligosaccharidesPrincipal Investigator
- Principal Investigator
  
  下田恵
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Oita University
Efficient DDS using biological nanoparticles hybridized with gluco-prodrugsPrincipal Investigator
- Principal Investigator
  
  Shimoda Kei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Oita University
Anticancer-agent glycoside conjugates incorporated in bio-nanocapsules for hepatocellular carcinoma treatmentPrincipal Investigator
- Principal Investigator
  
  Shimoda Kei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Oita University
Glycosylation using plant enzymes to produce anti-histamine agent
- Principal Investigator
  
  Hamada Hiroki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Okayama University of Science
Synthesis of highly water-soluble taxol derivativesPrincipal Investigator
- Principal Investigator
  
  Shimoda Kei
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Oita University
Development on new methodology for optical resolution using plant glycosyltransferases and its pharmacological exploitationPrincipal Investigator
- Principal Investigator
  
  SHIMODA Kei
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Oita University
コンビナトリアルバイオトランスフォーメーションによる低副作用医薬品の開発Principal Investigator
- Principal Investigator
  
  下田恵
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Oita University
固定化複合酵素バイオリアクターによる高機能化光学活性医薬品の開発Principal Investigator
- Principal Investigator
  
  下田恵
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  大分医科大学
Protection Systems in Plant Cells -- A Mechanism of Apoptosis with Monoterpenoids
- Principal Investigator
  
  IZUMI Shunsuke
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Hiroshima University
Chemical elucidation for the mechanism of the defense reaction of plant cells
- Principal Investigator
  
  HIRATA Toshifumi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Hiroshima University

[Journal Article] Effect of Magnesium Ion on the Radical-Scavenging Rate of Pterostilbene in an Aprotic Medium: Mechanistic Insight into the Antioxidative Reaction of Pterostilbene2022
- Author(s)
  Nakanishi Ikuo、Shoji Yoshimi、Ohkubo Kei、Ueno Megumi、Shimoda Kei、Matsumoto Ken-ichiro、Fukuhara Kiyoshi、Hamada Hiroki
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 2 Pages: 340-340
- DOI
  10.3390/antiox11020340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-20K12650, KAKENHI-PUBLICLY-20H04819
[Journal Article] Resveratrol oligosaccharides (gluco-oligosaccharides) effectively inhibit SARS-CoV-2 infection: Glycoside (polysaccharide) approach for treatment of COVID-19.2021
- Author(s)
  Hiroki Hamada, Hatsuyuki Hamada, Kei Shimoda
- Journal Title
  
  Natural Product Communications
  
  Volume: 16(5) Issue: 5 Pages: 1-3
- DOI
  10.1177/1934578x211012903
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12650
[Journal Article] Regioselective hydroxylation and dehydrogenation of capsaicin and dihydrocapsaicin by cultured cells of Phytolacca americana.2021
- Author(s)
  Kei Shimoda, Tsubasa Ono, Hiroki Hamada
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 1 Pages: 103-107
- DOI
  10.1093/bbb/zbaa004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12650
[Journal Article] Synthesis of ester-linked paclitaxel-glycoside conjugate as a water-soluble paclitaxel derivative---maltoside modification of paclitaxel through ester-linker (ester-spacer).2021
- Author(s)
  Hiroki Hamada, Hatsuyuki Hamada, Kei Shimoda
- Journal Title
  
  Natural Product Communications
  
  Volume: 16(9) Issue: 9 Pages: 1-3
- DOI
  10.1177/1934578x211038788
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12650
[Journal Article] Resveratrol oligosaccharide induces mRNA expression for SIRT2018
- Author(s)
  Hiroki Hamada, Kei Shimoda, Yasukazu Saitoh, Shouta Doi, Yuya Fujitaka, Tsubasa Ono, Hatsuyuki Hamada, Minami Araki
- Journal Title
  
  Natural Product Communications
  
  Volume: 13 Pages: 455-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01392
[Journal Article] Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene2017
- Author(s)
  Daisuke Uesugi, Hiroki Hamada, Kei Shimoda, Naoji Kubota, Shin-ichi Ozaki and Naoki Nagatani
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 81 Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01392
[Journal Article] Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene.2017
- Author(s)
  Daisuke Uesugi, Hiroki Hamada, Kei Shimoda, Naoji Kubota, Shin-ichi Ozaki, and Naoki Nagatani
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 81 Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05576
[Journal Article] Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene.2017
- Author(s)
  Daisuke Uesugi, Hiroki Hamada, Kei Shimoda, Naoji Kubota, Shin-ichi Ozaki, Naoki Nagatani
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: ８１ Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01392
[Journal Article] Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene.2017
- Author(s)
  Daisuke Uesugi, Hiroki Hamada, Kei Shimoda, Naoji Kubota, Shin-ichi Ozaki, Naoki Nagatani
- Journal Title
  
  Biosci., Biotechnol., Biochem.
  
  Volume: 81 Pages: 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05576
[Journal Article] Synthesis and pharmacological evaluation of glycosides of resveratrol, pterostilbene, and piceatannol.2015
- Author(s)
  K. Shimoda, N. Kubota, D. Uesugi, H. Hamada, M. Tanigawa, H. Hamada
- Journal Title
  
  Annals of the New York Academy of Sciences
  
  Volume: 1348 Pages: 141-149
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K05576
[Journal Article] Synthesis and pharmacological evaluation of glycosides of resveratrol, pterostilbene, and piceatannol.2015
- Author(s)
  K. Shimoda, N. Kubota, D. Uesugi, H. Hamada, M. Tanigawa, H. Hamada
- Journal Title
  
  Annals of the New York Academy of Sciences
  
  Volume: 1348 Pages: 141-149
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23590013
[Journal Article] Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol, and their anti-oxidant, anti-allergic, and neuroprotective activities.2014
- Author(s)
  D. Sato, N. Shimizu, Y. Shimizu, M. Akagi, Y. Eshita, S. Ozaki, N. Nakajima, K. Ishihara, N. Masuoka, H. Hamada, K. Shimoda, N. Kubota
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 78 Pages: 1123-1128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590013
[Journal Article] Regioselective Hydroxylation and Glucosylation of a- and b-Pinenes with Cultured Cells of Eucalyptus perriniana2013
- Author(s)
  Kei Shimoda, Naoji Kubota, Manabu Hamada, Ken Suwada, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Natural Product Communications
  
  Volume: 8 Pages: 847849-847849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590013
[Journal Article] Glycosylation of vanillin and 8-nordihydrocapsaicin by cultured Eucalyptus perriniana cells2012
- Author(s)
  D. Sato, Y. Eshita, H. Katsuragi, H. Hamada, K. Shimoda, N. Kubota
- Journal Title
  
  Molecules
  
  Volume: 17 Issue: 5 Pages: 5013-5020
- DOI
  10.3390/molecules17055013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590013, KAKENHI-PROJECT-23590803
[Journal Article] Formation of Tetrahydrocurcumin by Reduction of Curcumin with Cultured Plant Cells of Marchantia polymorpha2012
- Author(s)
  Kei Shimoda, Naoji Kubota, Hirotaka Hirano, Masahiro Matsumoto, Hatsuyuki Hamada and Hiroki Hamada
- Journal Title
  
  Natural Product Communications
  
  Volume: 7 Pages: 529-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590013
[Journal Article] Enzymatic resolution of (RS)-1-phenylalkylβ-D-glucosides to (R)-1-phenylalkyl β-primeverosides and (S)-1-phenylalkyl β-D-glucosides via plant xylosyltransferase2010
- Author(s)
  Kei Shimoda, Hisashi Katsuragi
- Journal Title
  
  Tetrahedron: Asymmetry Vol.21
  
  Pages: 2060-2065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Enzymatic resolution of (RS)-1-phenylalkyl β-D-glucosides to (R)-1-phenylalkyl β-primeverosides and (S)-1-phenylalkyl β-D-glucosides via plant xylosyltransferase2010
- Author(s)
  Kei Shimoda, Hisashi Katsuragi
- Journal Title
  
  Tetrahedron : Asymmetry
  
  Volume: 21 Pages: 2060-2065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Production of hesperetin glycosides by Xanthomonas campestris and cyclodextrin glucanotransferase and their anti-allergic activities2010
- Author(s)
  Kei Shimoda, Hiroki Hamada,
- Journal Title
  
  Nutrients Vol.2
  
  Pages: 171-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Production of Hesperetin Glycosides by Xanthomonas campestris and Cyclodextrin Glucanotransferase and Their Anti-allergic Activities2010
- Author(s)
  Kei Shimoda, Hiroki Hamada
- Journal Title
  
  Nutrients
  
  Volume: 2 Pages: 171-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of Fluorophenols by Plant Cell Cultures2009
- Author(s)
  Kei Shimoda, Naoji Kubota, Yoko Kondo, Daisuke Sato, Hiroki Hamada
- Journal Title
  
  Int.J.Mol.Sci. 10
  
  Pages: 1942-1949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of Fluorophenols by Plant Cell Cultures2009
- Author(s)
  下田恵, 久保田直治, 近藤陽子, 佐藤大介, 浜田博喜
- Journal Title
  
  Int. J. Mol. Sci. 10巻
  
  Pages: 1942-1949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of fluorophenols by plant cell cultures2009
- Author(s)
  Kei Shimoda, Naoji Kubota, Yoko Kondo,Daisuke Sato, Hiroki Hamada
- Journal Title
  
  Int. J. Mol. Sci Vol.10
  
  Pages: 1942-1949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of unnatural mono- and oligosaccharides of farnesol, geraniol, and (S)-perillyl alcohol by biocatalytic glycosylations2008
- Author(s)
  Kei Shimoda, Sou Sakamoto, Nobuyoshi Nakajima, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Chemistry Letters Vol.37
  
  Pages: 556-557
- NAID
  10021080720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of daidzin by the Eucalyptus cell cultures2008
- Author(s)
  Kei Shimoda, Noriaki Sato, Tatsunari Kobayashi, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Phytochemistry Vol.69
  
  Pages: 2303-2306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of Unnatural Mono-and Oligosaccharides of Farnesol, Geraniol and (S)-Perillyl Alcohol by Biocatalytic Glycosylations2008
- Author(s)
  K. Shimoda, S. Sakamoto, N. Nakajima, H. Hamada, H. Hamada
- Journal Title
  
  Chemistry Letters 37
  
  Pages: 556-557
- NAID
  10021080720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of Daidzin by the Eucalyptus Cell Cultures2008
- Author(s)
  K. Shimoda, N. Sato, T. Kobayashi, H. Hamada, H. Hamada
- Journal Title
  
  Phytochernisrry 69
  
  Pages: 2303-2306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of Unnatural Mono- and Oligosaccharides of Farnesol, Geraniol, and (S)-Perillyl Alcohol by Biocatalytic Glycosylations2008
- Author(s)
  下田恵, 坂本創, 中島伸佳, 浜田初幸, 浜田博喜
- Journal Title
  
  Chemistry Letters 37巻
  
  Pages: 556-557
- NAID
  10021080720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of α-tocopheryl disaccharides as potential antiallergic agents2007
- Author(s)
  Kei Shimoda, Yoko Kondo, Masaaki Akagi, Koichi Abe, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Chemistry Letters Vol.36
  
  Pages: 570-571
- NAID
  10018881366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of capsaicin and 8-nordihydorocapsaicin by cultured cells of Catharanthus roseus2007
- Author(s)
  Kei Shimoda, Soonil Kwon, Akiko Utsuki, Shingo Ohiwa, Hisashi Katsuragi, Naoko Yonemoto, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Phytochemistry Vol.68
  
  Pages: 1391-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of capsaicin and 8-nordihydorocapsaicin by cultured cells of Catharanthus roseus2007
- Author(s)
  Kei Shimoda
- Journal Title
  
  Phytochemistry 68
  
  Pages: 1391-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of α-tocopheryl disaccharides as potential antiallergic agents2007
- Author(s)
  Kei Shimoda
- Journal Title
  
  Chemistry Letters 36
  
  Pages: 570-571
- NAID
  10018881366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of curcumin β-maltooligosaccharides through biocatalytic glycosylation with Strophanthus gratus cell culture and cyclodextrin glucanotransferase2007
- Author(s)
  Kei Shimoda, Takafumi Hara, HatsuyukiHamada, Hiroki Hamada
- Journal Title
  
  Tetrahedron Letters Vol.48
  
  Pages: 4029-4032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of curcuminβ-maltooligosaccharides through biocatalytic glycosylation with Strophanthus gratus cell culture and cyclodextrin glucanotransferase2007
- Author(s)
  下田恵, 原隆文, 浜田初幸, 浜田博喜
- Journal Title
  
  Tetrahedron Letters 48巻
  
  Pages: 4029-4032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Synthesis of curcumin β-maltooligosaccharides through biocatalytic glycosylation with Strophanthus gratus cell culture and cyclodextrin glucanotransferase2007
- Author(s)
  Kei Shimoda
- Journal Title
  
  Tetrahedron Letters 48
  
  Pages: 4029-4032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790018
[Journal Article] Glycosylation of vitamin E homologue by cultured plant cells2006
- Author(s)
  Yoko Kondo, Kei Shimoda, Junichi Takimura, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Chemistry Letters 35巻・3号
  
  Pages: 324-325
- NAID
  10017273676
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Formation of water-soluble vitamin derivatives from lipophilic vitamins by cultured plant cells2006
- Author(s)
  Kei Shimoda, Yoko Kondo, Koichi Abe, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Tetrahedron Letters 47巻・16号
  
  Pages: 2695-2698
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Diastereoselective reduction of β-keto carbonyl compounds by cultured plant cells2006
- Author(s)
  Kei Shimoda, Naoji Kubota, Hatsuyuki Hamada, Hiroki Hamada
- Journal Title
  
  Tetrahedron Letters 47巻・10号
  
  Pages: 1541-1544
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Cellulose in affinity membrane applications for separation and purification of proteins2005
- Author(s)
  Naoji Kubota, Kei Shimoda
- Journal Title
  
  Recent Devel. Carbohydrate Res. 2巻
  
  Pages: 17-44
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Enantioselective Glucosylation of (±)-Secondary Alcohols with Plant Glucosyltransferases2004
- Author(s)
  Kei Shimoda, Naoji Kubota, Hiroki Hamada
- Journal Title
  
  Tetrahedron : Asymmetry 15
  
  Pages: 2319-2321
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Asymmetric Reduction of Enones with Synechococcus sp.PCC 79422004
- Author(s)
  Kei Shimoda, Naoji Kubota, Hiroki Hamada, Misato Kaji, Toshifumi Hirata
- Journal Title
  
  Tetrahedron : Asymmetry 15
  
  Pages: 1677-1679
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Asymmetric Transformation of Enol Acetates with Esterases from Marchantia polymorpha2004
- Author(s)
  Kei Shimoda, Naoji Kubota, Toshifumi Hirata, Takeshi Kawano
- Journal Title
  
  Journal of Molecular Catalysis B : Enzymatic 29
  
  Pages: 123-127
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Asymmetric Transformation of Enones with Synechococcus sp.PCC 79422004
- Author(s)
  Kei Shimoda, Naoji Kubota, Hiroki Hamada, Shin-ya Yamane, Toshifumi Hirata
- Journal Title
  
  Bulletin of the Chemical Society of Japan 77
  
  Pages: 2269-2272
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Asymmetric Reduction of 2-Substituted 2-Butenolides with Reductase from Marchantia polymorpha2004
- Author(s)
  Kei Shimoda, Naoji Kubota
- Journal Title
  
  Tetrahedron : Asymmetry 15
  
  Pages: 3827-3829
- Data Source
  KAKENHI-PROJECT-16790014
[Journal Article] Asymmetric Reduction of α,β-Unsaturated Carbonyl Compounds with Reductases from Nicotiana tabacum2004
- Author(s)
  Kei Shimoda, Naoji Kubota, Hiroki Hamada
- Journal Title
  
  Tetrahedron : Asymmetry 15
  
  Pages: 2443-2446
- Data Source
  KAKENHI-PROJECT-16790014
[Presentation] プテロスチルベンのラジカル消去反応に対するマグネシウムイオンの効果2021
- Author(s)
  中西郁夫、荘司好美、大久保敬、上野恵美、下田恵、小澤俊彦、福原潔、濱田博喜、松本謙一郎
- Organizer
  第141回　日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K12650
[Presentation] ヨウシュヤマゴボウ培養細胞による配糖化反応と配糖化酵素2018
- Author(s)
  濱田博喜, 藤高侑也, 井上豪, 小崎伸一, 下田恵
- Organizer
  第36回日本植物細胞分子生物学会
- Data Source
  KAKENHI-PROJECT-16K01392
[Presentation] ヨウシュヤマゴボウ培養細胞由来糖転移酵素を用いたスチルベン誘導体の配糖化2017
- Author(s)
  濱田博喜,藤高侑也,荒木美奈実,上杉大介,下田恵,小崎紳一,井上豪
- Organizer
  第80回日本植物細胞分子生物学会
- Data Source
  KAKENHI-PROJECT-15K05576
[Presentation] ヨウシュヤマゴボウ培養細胞由来糖転移酵素を用いたスチルベン誘導体の配糖化2017
- Author(s)
  濱田博喜, 藤高侑也, 荒木美奈実, 上杉大介, 下田恵, 小崎紳一, 井上豪
- Organizer
  第80回日本植物細胞分子生物学会
- Data Source
  KAKENHI-PROJECT-16K01392
[Presentation] 植物培養細胞を用いたフラボン類の物質変換2016
- Author(s)
  下田恵,大西達也,土井翔太,上杉大介,小崎紳一,濱田博喜
- Organizer
  第34回日本植物細胞分子生物学会
- Place of Presentation
  信州大学　繊維学部（長野県上田市）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-16K01392
[Presentation] 植物培養細胞によるスチルベン誘導体の物質変換2016
- Author(s)
  下田恵・土井翔太・上杉大介・大西達也・小崎紳一・濱田博喜
- Organizer
  第96回日本化学会春季年会
- Place of Presentation
  京都　同志社大学
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-23590013
[Presentation] 植物培養細胞を用いたN-グリコシル化2016
- Author(s)
  荒木美奈実,川村章吾,中山騎維,小野翼,真鍋光一,下田恵,小崎紳一,濱田博喜
- Organizer
  第34回日本植物細胞分子生物学会
- Place of Presentation
  信州大学繊維学部長野県上田市
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K05576
[Presentation] Synthesis and evaluation of glycosides of trans-resveratrol,pterostillbene,and piceatannol2015
- Author(s)
  Shota Okada, Daisuke Uesugi, Noriyuki Nakayama, Shota Doi, Shogo Kawamura, Kei Shimoda, Shinichi Ozaki, Hiroki Hamada
- Organizer
  ISPSA2015 TOKUSHIMA
- Place of Presentation
  徳島
- Year and Date
  2015-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05576
[Presentation] トランスレスベラトロールの機能性解明2013
- Author(s)
  上杉大介、小崎紳一、下田恵、堀尾嘉幸、濱田博喜
- Organizer
  第93回日本化学会春季年会
- Place of Presentation
  滋賀　立命館大学びわこ・くさつキャンパス
- Data Source
  KAKENHI-PROJECT-23590013
[Presentation] 植物培養細胞によるモノテルペン類の水酸化および配糖化2013
- Author(s)
  諏訪田憲，下田恵，濱田博喜
- Organizer
  第17回　生体触媒化学シンポジウム
- Place of Presentation
  岡山理科大学50周年記念館（岡山県岡山市北区理大町1-1）
- Data Source
  KAKENHI-PROJECT-23590013
[Presentation] 植物由来糖転移酵素を活用した機能性配糖体の合成2012
- Author(s)
  濱田博喜, 松本匡弘, 下田恵, 久保田直治, 小崎紳一, 中山亨
- Organizer
  第９１回日本化学会春季年会
- Place of Presentation
  神奈川大学横浜キャンパス
- Data Source
  KAKENHI-PROJECT-23590013
[Presentation] The effective synthesis of the lead compounds of the drug development and food supplement-Glycosylation of flavanoids using plant cultured cells2010
- Author(s)
  Hiroki Hamada, Kei Shimoda, Nobuyoshi Nakajima
- Organizer
  環太平洋国際化学会議PACIFICHEM2010
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物由来糖転移酵素を活用した高機能性配糖体の合成2010
- Author(s)
  浜田博喜, 小原隆博, 山本涼平, 下田恵, 小崎紳一, 中山亨, 葛城寿史
- Organizer
  第52回天然有機化合物討論会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] The effective synthesis of the lead compounds of the drug development and food supplement-Glycosylation of flavanoids using plant cultured cells2010
- Author(s)
  Hiroki Hamada, Kei Shimoda, Nobuyoshi Nakajima
- Organizer
  環太平洋国際化学会議 PACIFICHEM2010
- Place of Presentation
  ハワイ
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物由来糖転移酵素を活用した高機能性配糖体の合成2010
- Author(s)
  浜田博喜,小原隆博,山本涼平,下田恵,小崎紳一,中山亨,葛城寿史
- Organizer
  第52回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物酵素触媒によるワンステップグリコシル化反応2009
- Author(s)
  浜田博喜, 大広あずさ, 木村江利子, 近藤舞, 佐藤大介, 下田恵
- Organizer
  第95回有機合成シンポジウム
- Place of Presentation
  慶応義塾大学
- Year and Date
  2009-06-10
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物酵素触媒によるワンステップグリコシル化反応2009
- Author(s)
  濱田博喜,大広あずさ,木村江利子,近藤舞,佐藤大介, 下田恵
- Organizer
  第95回有機合成シンポジウム
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物培養細胞を用いたフラバノン類の変換-水酸化と配糖化2009
- Author(s)
  山本涼平, 小林達成, 比嘉望, 下田恵, 中島伸佳, 浜田博喜
- Organizer
  日本化学会第89回春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物培養細胞によるモノテルペン類の配糖化2009
- Author(s)
  小林達成, 佐藤大介, 下田恵, 久保田直治, 浜田博喜
- Organizer
  日本化学会第89回春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物酵素触媒によるワンステップグリコシル化反応2009
- Author(s)
  濱田博喜, 大広あずさ, 木村江利子, 近藤舞, 佐藤大介, 下田恵
- Organizer
  第95回有機合成シンポジウム
- Place of Presentation
  慶応大学
- Year and Date
  2009-06-10
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] Glycosylation of biological active compound using plant cultured suspention cells2009
- Author(s)
  浜田博喜, 大広あずさ, 木村江利子, 近藤舞, 佐藤大介, 中島伸佳, 下田恵
- Organizer
  Plant Biology 2009
- Place of Presentation
  ハワイ
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] Glycosylation of biological active compound using plant cultured suspention cells2009
- Author(s)
  Hiroki Hamada,Azusa Ohiro,Eriko Kimura,Mai Kondo,Daisuke Sato,Nobuyosi Nakajima, Kei Shimoda
- Organizer
  Plant Biology 2009
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 辛くない唐辛子とブドウポリフェノールの機能解明2009
- Author(s)
  浜田博喜, 大広あすさ, 下田恵, 本間知夫
- Organizer
  日本化学会第89回春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物培養細胞を用いたフラバノン類の変換-水酸化と配糖化2008
- Author(s)
  山本涼平,小林達成,比嘉望,下田恵,中島伸佳,浜田博喜
- Organizer
  日本化学会第89回春季年会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 辛くない唐辛子とブドウポリフェノールの機能解明2008
- Author(s)
  浜田博喜,大広あずさ,下田恵,本間知夫
- Organizer
  日本化学会第89回春季年会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物培養細胞によるモノテルペン類の配糖化2008
- Author(s)
  小林達成,佐藤大介,下田恵,久保田直冶,浜田博喜
- Organizer
  日本化学会第89回春季年会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 生体触媒を活用した有用物質の生産2007
- Author(s)
  浜田博喜,小林達成,下田恵
- Organizer
  日本化学会第88回春季年会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物培養細胞によるモノテルペンの配糖化2007
- Author(s)
  浜田博喜,小林達成,佐藤大介,下田恵
- Organizer
  日本化学会第88回春季年会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] 植物培養細胞によるレスベラトロールの配糖化2007
- Author(s)
  小林達成,大広あずさ,石原浩二,中島伸佳,下田恵,浜田博喜
- Organizer
  日本化学会第88回春季年会
- Data Source
  KAKENHI-PROJECT-19790018
[Presentation] The glycosylation of phenolic compounds using plant cultured cells
- Author(s)
  Daisuke Uesugi, Kei Shimoda, Naoji Kubota, Hiroaki Hamada
- Organizer
  Active Enzyme Molecule
- Place of Presentation
  富山国際会議場（富山市）
- Year and Date
  2014-12-17 – 2014-12-19
- Data Source
  KAKENHI-PROJECT-23590013

1. HAMADA Hiroki (10164914)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
2. IZUMI Shunsuke (90203116)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HIRATA Toshifumi (80033926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. OHTA Shinji (60185270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ASHIDA Yoshiyuki (40212500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 桐明祐弥 (30827184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UESUGI Daisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 中西郁夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimoda Kei 下田 恵

SHIMODA Kei 下田 恵

下田 恵 シモダ ケイ

Research Projects

Research Products

Co-Researchers

脳へ移行するグルコースの特性から着想を得た、脳へ薬物を輸送する新技術の開発

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Development of blood-brain barrier-penetrating oligosaccharidesPrincipal Investigator

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Efficient DDS using biological nanoparticles hybridized with gluco-prodrugsPrincipal Investigator

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Anticancer-agent glycoside conjugates incorporated in bio-nanocapsules for hepatocellular carcinoma treatmentPrincipal Investigator

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Glycosylation using plant enzymes to produce anti-histamine agent

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Synthesis of highly water-soluble taxol derivativesPrincipal Investigator

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Development on new methodology for optical resolution using plant glycosyltransferases and its pharmacological exploitationPrincipal Investigator

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コンビナトリアルバイオトランスフォーメーションによる低副作用医薬品の開発Principal Investigator

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固定化複合酵素バイオリアクターによる高機能化光学活性医薬品の開発Principal Investigator

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Protection Systems in Plant Cells -- A Mechanism of Apoptosis with Monoterpenoids

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Chemical elucidation for the mechanism of the defense reaction of plant cells

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[Journal Article] Effect of Magnesium Ion on the Radical-Scavenging Rate of Pterostilbene in an Aprotic Medium: Mechanistic Insight into the Antioxidative Reaction of Pterostilbene2022

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DOI

Data Source

[Journal Article] Resveratrol oligosaccharides (gluco-oligosaccharides) effectively inhibit SARS-CoV-2 infection: Glycoside (polysaccharide) approach for treatment of COVID-19.2021

Author(s)

Journal Title

Shimoda Kei 下田恵

SHIMODA Kei 下田恵

下田恵シモダケイ