TOMIYAMA Masahiko 冨山誠彦

… Alternative Names

富山誠彦トミヤママサヒコ

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Researcher Number	40311542
Other IDs
External Links
Affiliation (Current)	2025: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 弘前大学, 医学研究科, 教授 2016 – 2018: 弘前大学, 医学研究科, 研究員 2011 – 2015: 弘前大学, 医学(系)研究科(研究院), 研究員 2014: 弘前大学, 大学院医学研究科, 客員研究員 2012: 弘前大学, 医学(系)研究科(研究院), 客員研究員 … More 2010 – 2011: 弘前大学, 大学院・医学研究科, 客員研究員 2008: 弘前大学, 大学院・医学研究科, 客員研究員 2007 – 2008: 弘前大学, 大学院・医学研究科, 准教授 2006: Hirosaki University, School of Medicine, Associate Professor, 医学部, 助教授 2006: 弘前大学, 医学部附属病院, 助教授 2002 – 2004: 弘前大学, 医学部附属病院, 助手 2000 – 2002: 弘前大学, 医学部, 助手 2000: 弘前大学, 医学部・附属病院, 助手 1999: 弘前大学, 医学部付属病院, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Cerebral neurosurgery / Neurology / Neurology Except Principal Investigator Neurology / Environmental physiology(including physical medicine and nutritional physiology) / Neurology / Anesthesiology/Resuscitation studies / Basic Section 52020:Neurology-related / Basic Section 59010:Rehabilitation science-related … More / Basic Section 52040:Radiological sciences-related / Basic Section 48020:Physiology-related / Nerve anatomy/Neuropathology / Anesthesiology / Environmental physiology (including Physical medicine and Nutritional physiology) / Laboratory animal science Less
Keywords	Principal Investigator GABA / 遅発性ジスキネジア / 淡蒼球内節 / L-DOPA / パーキンソン病 / L-dopa誘発ジスキネジア / 遺伝性ジストニア / dendritic spine / spiny projection neuron / tardive dyskinesia … More / 淡蒼球外節 / エンケファリン / ダイノルフィン / パーキンソニズム / 線条体神経細胞 / 関節路線状体神経細胞 / 直接路線条体神経細胞 / 直接路神経細胞 / medial globus pallidus / dyskinesia / Parkinson's disease / レボドーパ / ジスキネジア / 末梢神経 / 自律神経 / αシヌクレイン / 生検 / 皮膚 / L－ドパ / 早期パーキンソン病 / 表皮内神経密度 / L-ドパ / 皮膚生検 / 多系統萎縮症 / Lewy neurite / リン酸化αシヌクレイン / 興奮性アミノ酸 / ヒト脊髄 / mGluR / 代謝型グルタミン酸受容体 / 運動ニューロン病 / in situ hybridization / AMPA受容体 / グルタミン酸受容体 / 筋萎縮性側索硬化症 … More Except Principal Investigator パーキンソン病 / GABA / 運動介入 / 脳 / 社会的孤立 / ストレス / 発達障害 / NUB1 / tau / Aβ / Synucleinopathy / Lewy body / シヌクレイノパチー / 多系統萎縮症 / レビー小体 / αシヌクレイン / ジスキネジア / 発達 / 受容体トラフィッキング / GABA-A受容体 / 麻酔薬 / 性差 / 不安 / トニック抑制 / アルツハイマー病 / イオンチャネル / 遺伝子改変動物 / 疾患モデル / 脳・神経 / L-ドパ / 加齢 / シナプス可塑性 / 神経可塑性 / 樹状突起上スパイン / L-ドパ誘発ジスキネジア / 脳解析 / ミエリンマップ / MRI / 社会的ストレス / ネグレクト / 母子分離マウス / 記憶機能低下 / 雌雄差 / 母子分離 / バルプロ酸ナトリウム / 超音波音声 / 自閉症モデル / 常同行動 / 記憶・学習障害 / バルプロ酸投与マウス / 行動解析 / バルプロ酸 / マウス / 自閉症 / Multople system atrophy / Parkinson''s disease / α-Synuclein / NUBI / Therapy / Transgenic mouse / Neuronal cell death / Alzheimer's disease / As / 治療法 / トランスジェニックマウス / 神経細胞死 / Ubiquitin-like protein / Multiple system atrophy / Parkinson's disease / Beta-synuclein / Alpha-synuclein / シンフィリン / ユビキチン / NEDD8 / ユビキチン様蛋白 / βシヌクレイン / subthalamic nucleus stimulation / pallidotomy / glutamic acid decarboxylase / 5-HT agonist / GABAergic neuron / motor sensitization / dyskinesia / 6-OH model rat / in situ hybridization / in vivo microdialysis / レボドパ / In situ hybridization / In vivo microdialysis / NMDA型グルタミン酸受容体 / ドパミン代謝 / セロトニンニューロン / 視床下核刺激術 / 淡蒼球内節破壊術 / GABA作動性神経ニューロン / 淡蒼球内節 / 8-OH-DPAT / 6-OHDAモデルラット / シナプス抑制 / PRIP1-KO / トニック / サブユニット / GABA受容体 / 脳の性差 / トラフィッキング / extrasynaptic / 受容体可視化 / 脱リン酸化調節 / extrasynaptic GABA-A 受容体 / tonic GABA response / 受容体trafficking / 麻酔薬作用 / tonic inhibition / リン酸化 / タンパク輸送 / 麻酔薬作用機序 / 情報伝達 / 薬理学 / 神経科学 / Synapse / Tonic / GABAA受容体 / 抑制 / 臨床応用 / 治療 / 診断 / オリゴマー / 神経病態生化学 / 行動薬理 / 慢性疼痛 / 認知 / AChチャネル / てんかん Less

Hyperkinetic Movement Disorderの発現機序の解明とGABA放出抑制薬による治療Principal Investigator
- Principal Investigator
  
  冨山誠彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
性差と脳内GABA変調から探る社会的孤立状態に置かれたこころの病態解析と治療法の確立
- Principal Investigator
  
  山田順子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Aomori Chuo Junior College
Effects of aging on synaptic plasticity in a rat model of Parkinson's disease
- Principal Investigator
  
  西嶌春生
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
パーキンソン病の早期診断における脳定量MRIミエリンマップに関する研究
- Principal Investigator
  
  藤田大真
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hirosaki University
The role of plastic changes of striatal spiny projection neurons in the development of tardive dyskinesiaPrincipal Investigator
- Principal Investigator
  
  Tomiyama Masahiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
Pathophysiological analysis of mental disorder caused by disturbance of GABAergic system in the brain due to maternal separation stress and search for treatment methods
- Principal Investigator
  
  YAMADA JUNKO
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Hirosaki University
The clinical condition analysis and search of the early therapy of the autistic model mouse in view of GABA change in the developmental brain.
- Principal Investigator
  
  YAMADA JUNKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Hirosaki University
Sex differences in the GABAergic system
- Principal Investigator
  
  Yamada Junko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Hirosaki University
Regulatory effects of GABA-A receptor trafficking and/or receptor phosphorylation on anesthetics
- Principal Investigator
  
  UENO Shinya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Hirosaki University
The pharmacological properties of tonic currents mediated by GABAA-Rs in BLA neurons
- Principal Investigator
  
  YAMADA JUNKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Hirosaki University
Research of novel regulatory mechanism of general anesthetics through receptor trafficking
- Principal Investigator
  
  UENO Shinya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Clinical availability of skin biopsy in the diagnosis of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  TOMIYAMA Masahiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Development and clinical application of novel methods for diagnosis and therapy of Alzheimer disease by regulation of neurotoxic oligomer
- Principal Investigator
  
  SHOJI Mikio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Establishment of animal model harboring a homologous mutation ofhuman epilepsy and analysis of genomics"
- Principal Investigator
  
  UENO Shinya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hirosaki University
認知機能異常動物モデルを用いた慢性疼痛機構の解明
- Principal Investigator
  
  上野伸哉
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Role of NUB1 in inclusion body formation in neurodegenerative disorders
- Principal Investigator
  
  WAKABAYASHI Koichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Hirosaki University
Development of therapy for deposits of AB and tau in Alzheimer disease.
- Principal Investigator
  
  SHOJI Mikio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
  Okayama University
Mechanisms of the developmert of L-DOPA-induced dyskinesiasPrincipal Investigator
- Principal Investigator
  
  TOMIYAMA Masahiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  HIROSAKI UNIVERSITY
Molecular pathomechanisms in alpha-synucleinopathis
- Principal Investigator
  
  WAKABAYASHI Koichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
Change of dopamine and serotonin metabolism, and NMDA-type glutamate receptors in the brain of Parkinson's disease
- Principal Investigator
  
  MATSUNAGA Muneo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
正常ヒトおよび筋萎縮性側索硬化症脊髄におけるグルタミン酸受容体の検討Principal Investigator
- Principal Investigator
  
  冨山誠彦 (富山誠彦)
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University

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All Journal Article Presentation Book

[Book] 「薬剤誘発性ジスキネジアと淡蒼球内節に関する研究動向」in 「Annual Review 神経 2024」2024
- Author(s)
  西嶌春生，中村崇志，冨山誠彦
- Total Pages
  6
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23K06941
[Book] Advance in Brain Research : Cerebrovascular disease and neurodegeneration2003
- Author(s)
  TOMIYAMA M
- Total Pages
  6
- Publisher
  Elsevier
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Book] Advance in Brain Research : Cerebrovascular disease and neurodegeneration2003
- Author(s)
  TOMIYAMA M
- Total Pages
  6
- Publisher
  International Congress Series, Elsevier
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] GABA storage and release from direct pathway neurons account for the enhanced short-duration response of L-dopa in Parkinson's disease2024
- Author(s)
  Nishijima Haruo、Tomiyama Masahiko
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 456 Pages: 122844-122844
- DOI
  10.1016/j.jns.2023.122844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06941, KAKENHI-PROJECT-21K07410
[Journal Article] Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming2023
- Author(s)
  Nakamura Takashi、Nishijima Haruo、Mori Fumiaki、Kinoshita Iku、Kon Tomoya、Suzuki Chieko、Wakabayashi Koichi、Tomiyama Masahiko
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 1169336-1169336
- DOI
  10.3389/fnins.2023.1169336
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06802, KAKENHI-PROJECT-23K06941, KAKENHI-PROJECT-21K07410, KAKENHI-PROJECT-23K24209
[Journal Article] Altered amantadine effects after repetitive treatment for l-dopa-induced involuntary movements in a rat model of Parkinson’s disease2023
- Author(s)
  Murakami Yoshiki、Nishijima Haruo、Nakamura Takashi、Furukawa Tomonori、Kinoshita Iku、Kon Tomoya、Suzuki Chieko、Tomiyama Masahiko
- Journal Title
  
  Neuroscience Letters
  
  Volume: 806 Pages: 137248-137248
- DOI
  10.1016/j.neulet.2023.137248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11747, KAKENHI-PROJECT-21K07410
[Journal Article] Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motorcortex of a rat model of levodopa-induced dyskinesia.2014
- Author(s)
  3.Ueno T, Yamada J, Nishijima H, Arai A, Migita K, Baba M, Ueno s, Tomiyama M.
- Journal Title
  
  Neurobiology of Disease.
  
  Volume: 64 Pages: 142-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460314
[Journal Article] Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia model2014
- Author(s)
  Nishijima H, Suzuki S, Kon T, Funamizu Y, Ueno T, Haga R, Suzuki C, Arai A, Kimura T, Suzuki C, Meguro R, Miki Y, Yamada J, Migita K, Ichinohe N, Ueno S, Baba M, Tomiyama M
- Journal Title
  
  Mov Disord
  
  Volume: 29 Suppl 3 Issue: 3 Pages: 336-343
- DOI
  10.1002/mds.25826
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22135007, KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-24650225, KAKENHI-PUBLICLY-25110740, KAKENHI-PROJECT-25670663, KAKENHI-PROJECT-23590706
[Journal Article] Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motorcortex of a rat model of levodopa-induced dyskinesia.2014
- Author(s)
  Ueno T, Yamada J, Nishijima H, Arai A, Migita K, Baba M, Ueno s, Tomiyama M.
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 64 Pages: 142-9
- DOI
  10.1016/j.nbd.2013.12.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-25670663, KAKENHI-PROJECT-26460693
[Journal Article] Morphologic changes of dendritic spines of striatal projection neurons in a rat model of L-DOPA-induced dyskinesia.2014
- Author(s)
  4.Nishijima H, Suzuki S, Kon T, Funamizu Y, Ueno T, Haga R, Miki Y, Suzuki C, Arai A, Kimura T, Suzuki C, Meguro R, Yamada J, Migita K, Ichinohe N, Ueno S, Baba M, Tomiyama M.
- Journal Title
  
  Movement disorders
  
  Volume: 29 Pages: 336-43
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460314
[Journal Article] Drebrin immunoreactivity in the striatum of a rat model of levodopa-induced dyskinesia.2013
- Author(s)
  Nishijima H, Arai A, Kimura T, Mori F, Yamada J, Migita K, Wakabayashi K, Baba M, Ueno S, Tomiyama M.
- Journal Title
  
  Neuropathology
  
  Volume: 33 Issue: 4 Pages: 391-6
- DOI
  10.1111/neup.12009
- URL
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=23241013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-23659735, KAKENHI-PROJECT-25670663
[Journal Article] Dysfunction of extrasynaptic GABAergic transmission in phospholipase C-related, but catalytically inactive protein 1 knockout mice is associated with an epilepsy phenotype.2012
- Author(s)
  Zhu G, Yoshida S, Migita K, Yamada J, Mori F, Tomiyama M, Wakabayashi K, Kanematsu T, Hirata M, Kaneko S, Ueno S, Okada M.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 340 Pages: 520-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659735
[Journal Article] Dysfunction of extrasynaptic GABAergic transmission in PRIP-1 KO mice is associated with an epilepsy phenotype.2011
- Author(s)
  1.Zhu G., Yoshida S., Migita K., Yamada J., Mori F., Tomiyama M., Wakabayashi K., Kanematsu T., Hirata M., Kaneko S., Ueno S and Okada M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 340 (3): Pages: 520-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590276
[Journal Article] Dysfunction of extrasynaptic GABAergic transmission in PRIP-1 KO mice is associated with an epilepsy phenotype2011
- Author(s)
  Zhu G., Yoshida S., Migita K., Yamada J., Ueno S
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 340(3) Issue: 3 Pages: 520-8
- DOI
  10.1124/jpet.111.182386
- URL
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22128345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590229, KAKENHI-PROJECT-22390224, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-23659564, KAKENHI-PROJECT-23659735
[Journal Article] Phenotypes of pain behavior in phospholipase C-related but catalytically inactive protein type 1 knockout mice.2011
- Author(s)
  Migita K., Tomiyama M., Yamada J., Fukuzawa M., Kanematsu T., Hirata M., Ueno S
- Journal Title
  
  Molecular pain
  
  Volume: 7 Pages: 79-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590276
[Journal Article] Phenotypes of pain behavior in phospholipase C-related but catalytically inactive protein type 1 knockout mice2011
- Author(s)
  Migita K., Tomiyama M., Yamada J., Fukuzawa M., Kanematsu T., Hirata M., Ueno S
- Journal Title
  
  Molecular pain
  
  Volume: 7 Pages: 79-79
- DOI
  10.1186/1744-8069-7-79
- URL
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22008183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590229, KAKENHI-PROJECT-21249089, KAKENHI-PROJECT-23590276, KAKENHI-PROJECT-23659735, KAKENHI-PROJECT-23659782
[Journal Article] Clinical availability of skin biopsy in diagnosis of Parkinson's disease2010
- Author(s)
  Miki Y, Tomiyama M, et al.
- Journal Title
  
  Neurosci Lett
  
  Volume: 469 Pages: 357-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590952
[Journal Article] Clinical availability of skin biopsy in the diagnosis of Parkinson's disease2010
- Author(s)
  Miki Y, Tomiyama M, Arai Aほか7 名
- Journal Title
  
  Neurosci Lett
  
  Volume: 469 Pages: 357-9
- Data Source
  KAKENHI-PROJECT-22590952
[Journal Article] An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis.2009
- Author(s)
  Wakasaya Y, Watanabe M, Tomiyama M, Suzuki C, Jackson M, Fujimuro M, Kimura T, Seino Y, Kawarabayashi T, Yamamoto-Watanabe Y, Matsubara E, Shirahama I, Takamura A, Nakahata N, Shoji M.
- Journal Title
  
  Intern Med. 48
  
  Pages: 1311-3
- NAID
  130000121961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, Mori F, Takahara T, Saito R, Miura Y, Kishi A, Tomiyama M, Sato A, Kojima T, Fukuma G, Wakabayashi K, Hase K, Ohno H, Kijima H, Ta kano Y, Mitsudome A, Kaneko S & Hirose S.
- Journal Title
  
  Journal of Neuroscience 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] Reuptake of L-DOPA-derived extracellular DA in the striatum of a rodent model of Parkinson's disease via norepinephrine transporter2008
- Author(s)
  Arai A, Tomiyama M, Kannari K, Kimura T, Suzuki C, Watanabe M, Kawarabayashi T, Shen H, Shoji M
- Journal Title
  
  Synapse 62(8)
  
  Pages: 632-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Exacerbation of chronic pancreatitis induced by anticholinesterase medications in myasthenia gravis2008
- Author(s)
  Tomiyama M, Shoji M
- Journal Title
  
  Eur J Neurol 15(5)
  
  Pages: 40-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] A novel mutation in the arylsulfatase A gene associated with adult-onset metachromatic leukodystrophy without clinical evidence of neuropathy2008
- Author(s)
  Suzuki C, Watanabe M, Tomiyama M, Sugimoto K, Nanba E, Jackson M, Kimura T, Seino Y, Wakasaya Y, Kawarabayashi T, Miki Y, Yamamoto-Watanabe Y, Shoji M
- Journal Title
  
  Eur Neurol 60(6)
  
  Pages: 310-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] A small trinucleotide expansion in the TBP gene gives rise to a sporadic case of SCA17 with abnormal putaminal findings on MRI2008
- Author(s)
  Watanabe M, Monai N, Jackson M, Yamamoto-Watanabe Y, Ikeda Y, Suzuki C, Tomiyama M, Kawarabayashi T, Kimura T, Seino Y, Wakasaya Y, Miki Y, Matsubara E, Shoji M
- Journal Title
  
  Intern Med 47(24)
  
  Pages: 2179-82
- NAID
  130000079782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] Rats Harboring S284L Chrna4 MutationShow Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal LobeEpilepsy Phenotyp J2008
- Author(s)
  Zhu G, Okada M, Yoshida S, Ueno S, MoriF, Takahara T, Saito R, Miura Y, Kishi A,Tomiyama M, Sato A, Kojima T, Fukuma G,Wakabayashi K, Hase K, Ohno H, Kijima H, Takano Y, Mitsudome A, Kaneko S & Hirose S.
- Journal Title
  
  Neurosci 28
  
  Pages: 12465-12476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300137
[Journal Article] アキレス腱反射減弱をともなった30歳代の認知症例2007
- Author(s)
  鈴木千恵子, 新井陽, 木村珠喜, 若佐谷保仁, 清野祐輔, 冨山誠彦, 馬場正之, 東海林幹夫, 杉本一博
- Journal Title
  
  臨床脳波 49
  
  Pages: 369-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390233
[Journal Article] A serotonin 5-HT1A receptor gonist prevents behavioral sensitizationto L-DOPA in a rat model of Parkinson's disea2005
- Author(s)
  TOMIYAMA M
- Journal Title
  
  NEUROSCIENCE RESEARCH 52
  
  Pages: 185-194
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] A serotonin 5-HT1A receptor gonist prevents behavioral sensitizationto L-DOPA in a rat model of Parkinson's disease2004
- Author(s)
  M.Tomiyama, T.Kimura, T.Maeda, K.Kannari, M.Matsunaga, M.Baba
- Journal Title
  
  NEUROSCI RES 52
  
  Pages: 185-194
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] Hypertrophy of medial globus pallidus and substantia nigra reticulata2004
- Author(s)
  TOMIYAMA M
- Journal Title
  
  NEUROPATHOLOGY 24
  
  Pages: 290-295
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] Hypertrophy of medial globus pallidus and substantia nigra reticulata in 6-OHDA-lesioned rats treated with L-DOPA2004
- Author(s)
  TOMIYAMA M
- Journal Title
  
  NEUROPATHOLOGY 24
  
  Pages: 290-295
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] Upregulation of striatal Adenosine A2A receptor mRNA in 6-OHDA-lesion2004
- Author(s)
  TOMIYAMA M
- Journal Title
  
  SYNAPSE 52
  
  Pages: 218-222
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] Hypertrophy of medial globus pallidus and substantia nigra reticulata in 6-OHDA-lesioned rats treated with L-DOPA2004
- Author(s)
  M.Tomiyama, F.Mori, T.Kimura, N.Ichinohe, K.Wakabayashi, M.Matsunaga, M.Baba.
- Journal Title
  
  NEUROPATHOLOGY 24
  
  Pages: 290-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] Upregulation of striatal adenosine A2A receptor mRNA in 6-OHDA-Lesioned rats intermittently treated with L-DOPA2004
- Author(s)
  M.Tomiyama, T.Kimura, T.Maeda, H.Tanaka, K.Kannari, M.Baba.
- Journal Title
  
  SYNAPSE 52
  
  Pages: 218-222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Journal Article] Upregulation of striatal Adenosine A2A receptor mRNA in 6-OHDA-lesion rats intermittently treated with L-DOPA2004
- Author(s)
  TOMIYAMA M
- Journal Title
  
  SYNAPSE 52
  
  Pages: 218-222
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591506
[Presentation] 遅発性ジスキネジアと淡蒼球内節内接の携帯異常2023
- Author(s)
  引地浩基、冨山誠彦
- Organizer
  日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07410
[Presentation] Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming2023
- Author(s)
  Nakamura T, Tomiyama M
- Organizer
  Movement Disorder Sciety, Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07410
[Presentation] GABAA receptor via phospholipase C-related but catalytically inactive protein type 1 in the spinal cord participate in abnormal pain sensation2012
- Author(s)
  Keisuke Migita1, Masahiko Tomiyama1, Junko Yamada1, Yoshikazu Nikaido1, Takashi Kanematsu2, Masato Hirata3 and Shinya Ueno1
- Organizer
  SFN 2012
- Place of Presentation
  ニューオリンズ（北米）
- Data Source
  KAKENHI-PROJECT-23590276
[Presentation] PRIP-1ノックアウトマウスの痛覚異常は脊髄におけるGABA作動性シナプス伝達異常が関与している2012
- Author(s)
  右田啓介、冨山誠彦、山田順子、二階堂義和、兼松隆、平田雅人、上野伸哉
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23659735
[Presentation] 皮膚生検はパーキンソン病の診断に有用か?2011
- Author(s)
  冨山誠彦, 新井陽,杉本一博ほか 8 名
- Organizer
  日本神経学会学術大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22590952
[Presentation] Morphologic changes of spines in the striatum of a rat model of L-DOPA-induced dyskinesias2011
- Author(s)
  Nishijima H., Tomiyama M., Arai A., Meguro R., Yamada J., Migita K., Ichinohe N., Shinya U.
- Organizer
  Neuroscience 2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590276
[Presentation] Differences in intraepidermal nerve fiber density between Parkinson's disease and multisystem atrophy2011
- Author(s)
  Tomiyama M, Arai A, Sugimoto, Kほか7名
- Organizer
  International Congress of Parkinson's disease and Movement Disorders
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-22590952
[Presentation] パーキンソン病の生検皮膚における Lewy pathology の検討2010
- Author(s)
  三木康生,冨山誠彦,新井陽ほか8名
- Organizer
  日本神経病理学会総会
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22590952
[Presentation] 皮膚生検によるパーキンソン病と多系統萎縮症の鑑別2010
- Author(s)
  上野達哉、冨山誠彦, ほか
- Organizer
  日本神経学会総会
- Place of Presentation
  東京フォーラム(東京都)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22590952
[Presentation] 皮膚生検における表皮内神経密度解析によるパーキンソン病と多系統萎縮症の鑑別2010
- Author(s)
  上野達哉,冨山誠彦,新井陽,杉本一博ほか 7 名
- Organizer
  パーキンソン病運動障害コングレス
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590952
[Presentation] Clinical availability of skin biopsy in the diagnosis of Parkinson's disease2010
- Author(s)
  Tomiyama M, Arai A,ほか 8 名
- Organizer
  International Congress of Parkinson's disease and Movement Disorders
- Place of Presentation
  Buenos Aires, Argentine
- Data Source
  KAKENHI-PROJECT-22590952
[Presentation] Ataxia-ocularapr axia2(AOA2)の臨床遺伝学的検討とsenataxinの機能解析2008
- Author(s)
  渡辺光法, 藤室雅弘, 冨山誠彦, 瓦林毅, 鈴木千恵子, 木村珠喜, 三木康生, 若佐谷保仁, 清野祐輔, 東海林幹夫
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 当科におけるもの忘れ外来と脳脊髄液診断の現状2008
- Author(s)
  若佐谷保仁, 瓦林毅, 中畑直子, 清野祐輔, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗, 桑野良三
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβアミロイドはタウ蓄積を促進する2008
- Author(s)
  清野祐輔, 瓦林毅, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] CSF Tau correlates with Brain Tau In Tau Transgenic Mice2008
- Author(s)
  Takeshi Kawarabayashi, Yusuke Seino, Yasuhito Wakasaya, Mitsunori Watanabe, Tamaki Kimura, Chieko Suzuki, Masahiko Tomiyama, Etsuro Matsubara, Koichi Ishiguro, David Westaway, Peter St. George-Hyslop, Mikio Shoji
- Organizer
  ICAD2008
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 脳脊髄液タウは脳タウ蓄積と相関する2008
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗, 石黒幸一
- Organizer
  日本神経学会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 神経原線維変化と神経細胞死を再現するタウマウスモテルの作成2008
- Author(s)
  瓦林毅, 清野祐輔, 若佐谷保仁, 渡辺光法, 木村珠喜, 鈴木千恵子, 冨山誠彦, 東海林幹夫, 松原悦朗, 池田将樹, 針谷康夫
- Organizer
  日本老年医学会
- Place of Presentation
  千葉
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Multiple Sclerosis with chronic sialadenitis2007
- Author(s)
  C. Suzuki, M. Tomiyama, T Kawara bayashi, M. Shoji, M Baba
- Organizer
  17th meeting of the European Neurological Society
- Place of Presentation
  Rhodes Greece
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] XVII WFN World Congress on Parkinson's Disease and Related Disorders2007
- Author(s)
  T Kimura, M Tomiyama, A Arai, C Suzuki, T Kawarabayashi, M Shoji. Onset age or treatment age: Whichis a more important risk factor for L-DOPA-induced dyskinesia in Park inson's disease?
- Organizer
  XVII WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Enhanced GABA release in the medial globus pallidus of a rat model of L-DOPA-induced dyskinesia2007
- Author(s)
  Tomiyama M, Arai A, Kimura T, Watanabe M, Kawarabayashi T, Shoji M
- Organizer
  XVII WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Aβアミロイド蓄積は神経突起およびグリア細胞へのtau蓄積を促進する2007
- Author(s)
  清野祐輔, 瓦林毅, 若佐谷保仁, 新井陽, 木村珠喜, 鈴木千恵子, 冨山誠彦, 村上哲郎, 倉田智子, 松原悦朗, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Cortical neuronal and glial pathology in TgTauP301L transgenic mice2007
- Author(s)
  T. Kawarabayashi, Y. Seino, Y. Wakasaya, M. Watanabe, C. Suzuki, M. Tomiyama, E. Matsubara, N. Egashira, M. Takahashi, M. Fujiwara, G. A. Carlson, D. Westaway, P. S. George-Hyslop, M. Shoji
- Organizer
  XVII WFN World Congress on Parkinson's Disease and Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Enhanced GABArelease in the medial globus pallidus of a ratmodel of L-DOPA-induced dyskinesia2007
- Author(s)
  Tomiyama M, Arai A, Kimura T, Watanabe M, Kawarabayashi T, Shoji M.
- Organizer
  XVII WFN World Congress on Parkinson's Diseaseand Related Disorders
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-18300137
[Presentation] Analysis of amyloid angiopathy in Tg2576 Transgenic mouse model of Alzheimer's disease2007
- Author(s)
  T. Kawarabayashi, Y. Seino, Y. Wakasaya, T. Kimura, C. Suzuki, M. Tomiyama, E. Matsubara, M. Shoji
- Organizer
  Brain'07 and Brain PET'07
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] 超高齢者集団認知症検診におけるMini-Mental State Examination(MMSE)の妥当性の検討2007
- Author(s)
  若佐谷保仁、清野祐輔、瓦林毅、三木康生、木村珠喜、鈴木千恵子、渡辺光法、冨山誠彦、桑野良三、東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Enhanced GABA release in the medial globus pallidus of a rat model of L-DOPA-induced dyskinedia.2007
- Author(s)
  Tomiyama M, Arai A, Kimura T, Watanabe M, Kawarabayashi T, Shoji M.
- Organizer
  XVII WFN World Congress on Parkinson's Disease and RelatedDisorders.
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-18300137
[Presentation] Aβ amyloid accelerates accumulation of tau in neuronal processes2007
- Author(s)
  Y. Seino, Y. Wakasaya, T. Kawarabayashi, M. Watanabe, C. Suzuki, M. Tomiyama, E. Matsubara, M. Shoji
- Organizer
  日本認知症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Enhanced GABA release in the medial globus pallidus of a rat model of L-DOPA-induced dyskinesia.2007
- Author(s)
  Tomiyama M, Arai A, Kimura T, Watanabe M, Kawarabayashi T, Shoji M.
- Organizer
  XVII WFN World Congress on Parkinson's Disease and RelatedDisorders.
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-18659455
[Presentation] Aβ accumulation causes postsynaptic damage in Tg2576 mice2007
- Author(s)
  Y. Wakasaya, Y. Seino, T. Kawarabayashi, M. Watanabe, C. Suzuki, M. Tomiyama, E. Matsubara, M. Shoji,
- Organizer
  日本認知症学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390233
[Presentation] Niemann-Pick type C1遺伝子のloss of functionはtauopathyを促進する2007
- Author(s)
  東海林幹夫, 瓦林毅, 清野祐輔, 若佐谷保仁, 新井陽, 木村珠喜, 鈴木千恵子, 冨山誠彦, 村上哲郎, 倉田智子, 松原悦朗, 東海林幹夫
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19390233

1. YAMADA Junko (30334965)

# of Collaborated Projects: 9 results

# of Collaborated Products: 12 results
2. MIGITA Keisuke (10352262)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
3. UENO Shinya (00312158)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
4. MORI Fumiaki (60200383)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
5. WAKABAYASHI Koichi (50240768)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. 佐藤ちひろ (70757468)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 西嶌春生 (90858177)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. MATSBARA Etsuro (70219468)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
9. KAWARABAYASHI Takeshi (90186156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
10. FUKUZAWA Masashi (10231557)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. MORIYAMA Tomoko (90400134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. SHOJI Mikio (60171021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
13. TANJI Kunikazu (10271800)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 小枝周平 (00455734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 古川智範 (60402369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. ARAKI Kimi (90211705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OKAMOTO Motohiro (10281916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. KANEKO Sunao (40106852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. WATANABE Mitsunori (90251107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
20. ARAI Akira (80422062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
21. SUGIMOTO Kazuhiro (70271799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. NIKAIDO Yoshikazu (50613478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. MATSUNAGA Muneo (80003599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. IMAIZUMI Tadaatsu (90232602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KANNARI Kazuya (20241466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. ABE Koji (20212540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. IKEDA Masaki (50222899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 朱剛 (80400133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 早狩誠 (80156421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 鈴木千恵子 (50396404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
31. 関谷徹治 (70154656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 中村崇志 (00880014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 藤田大真 (30720742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 掛田伸吾 (30352313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 渡邉啓太 (70565663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 一戸紀孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOMIYAMA Masahiko 冨山 誠彦

富山 誠彦 トミヤマ マサヒコ

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Hyperkinetic Movement Disorderの発現機序の解明とGABA放出抑制薬による治療Principal Investigator

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The role of plastic changes of striatal spiny projection neurons in the development of tardive dyskinesiaPrincipal Investigator

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Clinical availability of skin biopsy in the diagnosis of Parkinson's diseasePrincipal Investigator

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Principal Investigator

Project Period (FY)

TOMIYAMA Masahiko 冨山誠彦

富山誠彦トミヤママサヒコ