MITSUZAWA Hiroaki 光澤博昭

… Alternative Names

光沢博昭ミツザワヒロアキ

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Researcher Number	40325874
Other IDs
Affiliation (based on the past Project Information) *help	2008: Sapporo Medical University, 医学部, 講師 2007: Sapporo Medical University, School of Medicine, Research Associate 2005 – 2006: 札幌医科大学, 医学部, 助手 2002: 札幌医大, 医学部, 助手 2001: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Otorhinolaryngology Except Principal Investigator Respiratory organ internal medicine / Biological Sciences
Keywords	Principal Investigator 自然免疫 / 肺サーファクタント蛋白質 / コレクチン / メタロプロテアーゼ / 間質性肺炎 / 肺気腫 / マトリックスメタロプロテアーゼ / 肺サーファクタント / 感染症 / マンノース受容体 … More / マンノース結合レクチン / 非定型抗酸菌 / Toll様受容体 / CD14 … More Except Principal Investigator SP-D / SP-A / MD-2 / endotoxin / pulmonary inflammation / Toll-like receptor / collectin / pulmonary surfactant / TLR4 / エンドトキシン / 肺炎症 / トル様受容体 / コレクチン / 肺サーファクタント / 細菌貧食 / 細胞内寄生菌 / レジオネラ菌 / 非定型抗酸菌 / 細菌貪食 / マクロファージ / 肺コレクチン Less

肺コレクチンを介するマクロファージ細菌貪食の分子機構
- Principal Investigator
  
  KUROKI Yoshio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Surfactant protein regulates the activity of matrix metalloproteinesesPrincipal Investigator
- Principal Investigator
  
  MITSUZAWA Hiroaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Sapporo Medical University
Host defense system in the lung using pulmonary surfactant proteins and Toll-like reosptors
- Principal Investigator
  
  KUROKI Yoshio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Sapporo Medical University
肺サーファクタントアポ蛋白質による非定型抗酸菌感染防御機構の解明Principal Investigator
- Principal Investigator
  
  光澤博昭
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Sapporo Medical University
上気道におけるCD14およびTO11様受容体を介した生体防御機構の解明Principal Investigator
- Principal Investigator
  
  光沢博昭
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Sapporo Medical University

All 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] Immunomodulatory funcfions of pulmonary collectins In Collagen-Related Innate Immunity(Edited by Dave Kirkpatrik)2007
- Author(s)
  Mitsuzawa H
- Publisher
  Reseazch Signpost
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390241
[Book] Immunomodulatory functions of pulmonary collectins In Collagen-Related Lectins in Innate Immunity2007
- Author(s)
  Mitsuzawa H.
- Total Pages
  237
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-19041062
[Book] Immunomodulatory functions of pulmonary collectins.2007
- Author(s)
  Hiroaki Mitsuzawa
- Total Pages
  22
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-19590904
[Book] Immunomodulatory functions of pulmonary collectins In Collagen-Related Lectins in Innate Immunity2007
- Author(s)
  Mitsuzawa H
- Total Pages
  237
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-18390241
[Journal Article] Pulmonary surfactant protein D binds MD-2 through the carbohydrate recognition domain2008
- Author(s)
  Nie X, Nishitani C, Yamazoe M, Ariki S, Takahashi M, Shimizu T, Mitsuzawa H, Sawada K, Smith K, Crouch E, Nagae H, Takahashi H, Kuroki Y
- Journal Title
  
  Biochemistry 47
  
  Pages: 12878-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590904
[Journal Article] Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells2008
- Author(s)
  Chmura K, Bai X, Nakamura M, Kandasamy P, McGibney M, Kuronuma K, Mitsuzawa H, Voelker DR, Chan ED
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 295
  
  Pages: 220-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590904
[Journal Article] 6-Fluoro-8-methoxy-quinolone, gatifloxacin, downregulates IL-8 production in prostate cell line PC-32007
- Author(s)
  Takeyama K, Mitsuzawa H, Nishitani C, Shimizu T, Sano H, Kunishima Y, Takahashi S, Hotta H, Matsukawa M, Shibata K, Tsukamoto T, Kuroki Y
- Journal Title
  
  Antimicrob Agents Chemother 51(1)
  
  Pages: 162-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590904
[Journal Article] Immunomodulatory functions of pulmonary collectins2007
- Author(s)
  Mitsuzawa, H
- Journal Title
  
  In Collagen-Related Lectins in Innate Immunity (Edited by Dave Kirkpatrick) 237
  
  Pages: 179-190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390241
[Journal Article] The microtubule binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A J Biol Chem2007
- Author(s)
  Sano H, Ishino M, Kramer H, Shimizu T, Mitsuzawa H, Nishitani C, Kuroki Y
- Journal Title
  
  282
  
  Pages: 7973-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590904
[Journal Article] Recombinant soluble forms of extracellular Toll-like receptor 4 domain and MD-2 inhibit LPS binding on cell surface and dampen LPS-induced pulmonary inflammation mice2006
- Author(s)
  Mitsuzawa H
- Journal Title
  
  J Immunol 177
  
  Pages: 8133-8139
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390241
[Journal Article] Recombinant Soluble Forms of Extracellular Domain and MD-2 Inhibit Lipolysaccharide Binding on Cell Surface and Dampen Lipolysaccharide-Induced Pulmonary Inflammation in Mice.2006
- Author(s)
  Mitsuzawa H
- Journal Title
  
  J Immunol 177
  
  Pages: 8133-8139
- Data Source
  KAKENHI-PROJECT-17790536
[Journal Article] Recombinant soluble forms of extracellular Toll-like receptor 4 domain and MD-2 inhibits LPS binding on cell surface and dampen LPS-induced pulmonary inflammation in mice2006
- Author(s)
  Mitsuzawa, H
- Journal Title
  
  J Immunol 177
  
  Pages: 8133-8139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390241
[Journal Article] Recombinant soluble forms of extracellular Toll-like receptor 4 domain and MD-2 inhibit LPS binding on cell surface and dampen LPS-induced pulmonary inflammation in mice.2006
- Author(s)
  Mitsuzawa H
- Journal Title
  
  J Immunol 177
  
  Pages: 8133-8139
- Data Source
  KAKENHI-PROJECT-18390241
[Presentation] SP-Dによるマトリックスメタロプロテアーゼ活性制御2009
- Author(s)
  光澤博昭
- Organizer
  医化学フォーラム札幌2009
- Place of Presentation
  札幌
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590904
[Presentation] Recombinant soluble forms of extraellular Toll-like receptor 4 domain and MD-2 inhibit LPS binding on cell surface and dampen LPS-induced pulmonary inflammation in mice2006
- Author(s)
  Mitsuzawa H
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Snowmass,USA
- Year and Date
  2006-08-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390241
[Presentation] Recombinant soluble forms of extracellular Toll-like receptor 4 domain and MD-2 inhibit LPS binding on cell surface and dampen LPS-induced pulmonary inflammation in mice2006
- Author(s)
  Mitsuzawa, H
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Snowmass, USA
- Year and Date
  2006-08-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390241

1. KUROKI Yoshio (70161784)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. SHIMIZU Takeyuki (10339137)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. NISHITANI Chiaki (30381255)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. TAECAHASHI Motoko (00303941)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAHASHI Hiroki (60231396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MITSUZAWA Hiroaki 光澤 博昭

光沢 博昭 ミツザワ ヒロアキ

Research Projects

Research Products

Co-Researchers

肺コレクチンを介するマクロファージ細菌貪食の分子機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Surfactant protein regulates the activity of matrix metalloproteinesesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Host defense system in the lung using pulmonary surfactant proteins and Toll-like reosptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肺サーファクタントアポ蛋白質による非定型抗酸菌感染防御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

上気道におけるCD14およびTO11様受容体を介した生体防御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Immunomodulatory funcfions of pulmonary collectins In Collagen-Related Innate Immunity(Edited by Dave Kirkpatrik)2007

Author(s)

Publisher

Description

Data Source

[Book] Immunomodulatory functions of pulmonary collectins In Collagen-Related Lectins in Innate Immunity2007

Author(s)

Total Pages

Publisher

Data Source

[Book] Immunomodulatory functions of pulmonary collectins.2007

Author(s)

Total Pages

Publisher

Data Source

[Book] Immunomodulatory functions of pulmonary collectins In Collagen-Related Lectins in Innate Immunity2007

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Pulmonary surfactant protein D binds MD-2 through the carbohydrate recognition domain2008

Author(s)

Journal Title

Data Source

[Journal Article] Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells2008

Author(s)

Journal Title

Data Source

[Journal Article] 6-Fluoro-8-methoxy-quinolone, gatifloxacin, downregulates IL-8 production in prostate cell line PC-32007

Author(s)

Journal Title

Data Source

[Journal Article] Immunomodulatory functions of pulmonary collectins2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] The microtubule binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A J Biol Chem2007

Author(s)

Journal Title

Data Source

[Journal Article] Recombinant soluble forms of extracellular Toll-like receptor 4 domain and MD-2 inhibit LPS binding on cell surface and dampen LPS-induced pulmonary inflammation mice2006

Author(s)

Journal Title

Description

MITSUZAWA Hiroaki 光澤博昭

光沢博昭ミツザワヒロアキ