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ARAKAWA Ryosuke  荒川 亮介

ORCIDConnect your ORCID iD *help
Researcher Number 40350095
Affiliation *help 2016 – 2018 : 国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 成人精神保健研究部 , 室長
2011 : 放射線医学総合研究所, 分子イメージング研究センター, 博士研究員
Review Section/Research Field
Except Principal Investigator
Radiation science
Keywords
Except Principal Investigator
PET / 抗精神病薬 / 向精神薬 / ドーパミン受容体 / ドーパミン
  • Research Projects

    (1results)
  • Research Products

    (38results)
  • Co-Researchers

    (3People)
  •  Effects of antipsychotic drugs on pre-and postsynaptic dopaminergic functions measured by PET

    • Principal Investigator
      ITO Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      National Institute of Radiological Sciences

All 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Relation between presynaptic and postsynaptic dopaminergic functions measured by positron emission tomography : implication of dopaminergictone2011

    • Author(s)
      Ito H, Kodaka F, Takahashi H, Takano H, Arakawa R, Shimada H, Suhara T
    • Journal Title

      J Neurosci

      Volume : 31 Pages : 7886-7890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Serotonergic neurotransmission in the living human brain : A positron emission tomography study using [^<11>C]DASB and [^<11>C]WAY100635 in young healthy men2011

    • Author(s)
      Takano H, Ito H, Takahashi H, Arakawa R, Okumura M, Kodaka F, Otsuka T, Kato M, Suhara T
    • Journal Title

      Synapse

      Volume : 65 Pages : 624-633

    • DOI
      10.1002/syn.20883
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Effect of risperidone on high-affinity state of dopamine D_2 receptors : a PET study with agonist ligand [^<11>C](R)-2-CH_3O-N-n-propylnorapomorphine2011

    • Author(s)
      Kodaka F, Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Okumura M, Otsuka T, Nakayama K, Halldin C, Farde L, Suhara T
    • Journal Title

      Int J Neuropsychopharmacol

      Volume : 14 Pages : 83-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Relation between presynaptic and postsynaptic dopaminergic functions measured by positron emission tomography : implication of dopaminergic tone2011

    • Author(s)
      Ito H, Kodaka F, Takahashi H, Takano H, Arakawa R, Shimada H, Suhara T
    • Journal Title

      J Neurosci

      Volume : Vol.31 Pages : 7886-7890

    • URL
      http://www.jneurosci.org/content/31/21/7886.long
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Effect of risperidone on high-affinity state of dopamine D_2 receptors : a PET study with agonist ligand[^<11> C](R)-2-CH3O-N-n-propylnorapomorphine2011

    • Author(s)
      Kodaka F, Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Okumura M, Otsuka T, Nakayama K, Halldin C, Farde L, Suhara T
    • Journal Title

      Int J Neuropsychopharmacol

      Volume : Vol.14 Pages : 83-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Serotonergic neurotransmission in the living human brain : A positron emission tomography study using[^<11> C] DASB and[^<11> C] WAY100635 in young healthy men2011

    • Author(s)
      Takano H, Ito H, Takahashi H, Arakawa R, Okumura M, Kodaka F, Otsuka T, Kato M, Suhara T
    • Journal Title

      Synapse

      Volume : Vol.65 Pages : 624-633

    • URL
      http://onlinelibrary.wiley.com/doi/10.1002/syn.20883/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+on+9+June+from+10%3A00-12%3A00+BST+%2805%3A00-07%3A00+EDT%29+for+essential+maintenance
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Measurement error analysis for the determination of dopamine D_2 receptor occupancy using the agonist radioligand [^<11>C]MNPA.2010

    • Author(s)
      Shidahara M, Ito H, Otsuka T, Ikoma Y, Arakawa R, Kodaka F, Seki C, Takano H, Takahashi H, Turkheimer FE, Kimura Y, Kanno I, Suhara T
    • Journal Title

      J Cereb Blood Flow Metab

      Volume : 30 Pages : 187-195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Extrastriatal dopamine D_2 receptor occupancy in olanzapine-treated patients with schizophrenia.2010

    • Author(s)
      Arakawa R, Ito H, Okumura M, Takano A, Takahashi H, Takano H, Okubo Y, Suhara T
    • Journal Title

      Eur Arch Psychiatry Clin Neurosci

      Volume : 260 Pages : 345-350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Positron emission tomography measurement of dopamine D_2 receptor occupancy in the pituitary and cerebral cortex : relation to antipsychotic-induced hyperprolactinemia.2010

    • Author(s)
      Arakawa R, Okumura M, Ito H, Takano A, Takahashi H, Takano H, Maeda J, Okubo Y, Suhara T
    • Journal Title

      J Clin Psychiatry

      Volume : 71 Pages : 1131-1137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Extrastriatal dopamine D2 receptor occupancy in olanzapine-treated patients with schizophrenia2010

    • Author(s)
      Arakawa R, Ito H, Okumura M, Takano A, Takahashi H, Takano H, Okubo Y, Suhara T
    • Journal Title

      Eur Arch Psychiatry Clin Neurosci

      Volume : Vol.260 Pages : 345-350

    • URL
      http://www.springerlink.com/content/d15876721x0tqx19/
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Dopamine D_2 receptor occupancy by perospirone : a positron emission tomography study in patients with schizophrenia and healthy subjects2010

    • Author(s)
      Arakawa R, Ito H, Takano A, Okumura M, Takahashi H, Takano H, Okubo Y, Suhara T
    • Journal Title

      Psychopharmacology(Berl)

      Volume : Vol.209 Pages : 285-290

    • URL
      http://www.springerlink.com/content/j7038357525x8677/
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Measurement error analysis for the determination of dopamine D_2 receptor occupancy using the agonist radioligand[^<11> C] MNPA2010

    • Author(s)
      Shidahara M, Ito H, Otsuka T, Ikoma Y, Arakawa R, Kodaka F, Seki C, Takano H, Takahashi H, Turkheimer FE, Kimura Y, Kanno I, Suhara T
    • Journal Title

      J Cereb Blood Flow Metab

      Volume : Vol.30 Pages : 187-195

    • URL
      http://www.nature.com/jcbfm/journal/v30/n1/full/jcbfm2009193a.html
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Positron emission tomography inter-scanner differences in dopamine D_2 receptor binding measured with[^<11> C] FLB4572010

    • Author(s)
      Kodaka F, Ito H, Shidahara M, Takano H, Takahashi H, Arakawa R, Nakayama K, Suhara T
    • Journal Title

      Ann Nucl Med

      Volume : Vol.24 Pages : 671-677

    • URL
      http://www.springerlink.com/content/m70604270017g456/
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Quantitative analysis of dopamine transporters in human brain using[11C] PE2I and positron emission tomography : evaluation of reference tissue models2010

    • Author(s)
      Seki C, Ito H, Ichimiya T, Arakawa R, Ikoma Y, Shidahara M, Maeda J, Takano A, Takahashi H, Kimura Y, Suzuki K, Kanno I, Suhara T
    • Journal Title

      Ann Nucl Med

      Volume : Vol.24 Pages : 249-260

    • URL
      http://www.springerlink.com/content/7680221811nv4rlw/
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Positron emission tomography measurement of dopamine D_2 receptor occupancy in the pituitary and cerebral cortex : relation to antipsychotic-induced hyperprolactinemia2010

    • Author(s)
      Arakawa R, Okumura M, Ito H, Takano A, Takahashi H, Takano H, Maeda J, Okubo Y, Suhara T
    • Journal Title

      J Clin Psychiatry

      Volume : Vol.71 Pages : 1131-1137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Quantitative analysis of dopamine transporters in human brain using[^<11>C]PE2I and positron emission tomography : evaluation of reference tissuemodels.2010

    • Author(s)
      Seki C, Ito H, Ichimiya T, Arakawa R, Ikoma Y, Shidahara M, Maeda J, Takano A, Takahashi H, Kimura Y, Suzuki K, Kanno I, Suhara T
    • Journal Title

      Ann Nucl Med

      Volume : 24 Pages : 249-260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Positron emission tomography inter-scanner differences in dopamine D_2 receptor binding measured with[^<11>C]FLB457.2010

    • Author(s)
      Kodaka F, Ito H, Shidahara M, Takano H, Takahashi H, Arakawa R, Nakayama K, Suhara T
    • Journal Title

      Ann Nucl Med

      Volume : 24 Pages : 671-677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Dopamine D_2 receptor occupancy by perospirone : a positron emission tomography study in patients with schizophrenia and healthy subjects.2010

    • Author(s)
      Arakawa R, Ito H, Takano A, Okumura M, Takahashi H, Takano H, Okubo Y, Suhara T
    • Journal Title

      Psychopharmacology (Berl)

      Volume : 209 Pages : 285-290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with L-[β-^<11> C] DOPA : a stabilizing effect for dopaminergic neurotransmission?2009

    • Author(s)
      Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Kodaka F, Okumura M, Otsuka T, Suhara T
    • Journal Title

      J Neurosci

      Volume : Vol.29 Pages : 13730-13734

    • URL
      http://www.jneurosci.org/content/29/43/13730.long
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with^<11> C-AC-52162009

    • Author(s)
      Miyoshi M, Ito H, Arakawa R, Takahashi H, Takano H, Higuchi M, Okumura M, Otsuka T, Kodaka F, Sekine M, Sasaki T, Fujie S, Seki C, Maeda J, Nakao R, Zhang MR, Fukumura T, Matsumoto M, Suhara T
    • Journal Title

      J Nucl Med

      Volume : Vol.50 Pages : 1095-1101

    • URL
      http://jnm.snmjournals.org/content/50/7/1095.long
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Increase in thalamic binding of[^<11> C] PE2I in patients with schizophrenia : a positron emission tomography study of dopamine transporter2009

    • Author(s)
      Arakawa R, Ichimiya T, Ito H, Takano A, Okumura M, Takahashi H, Takano H, Yasuno F, Kato M, Okubo Y, Suhara T
    • Journal Title

      J Psychiatr Res

      Volume : Vol.43 Pages : 1219-1223

    • URL
      http://www.sciencedirect.com/science/article/pii/S0022395609000892
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Quantitative PET analysis of the dopamine D_2 receptor agonist radioligand^<11> C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain2009

    • Author(s)
      Otsuka T, Ito H, Halldin C, Takahashi H, Takano H, Arakawa R, Okumura M, Kodaka F, Miyoshi M, Sekine M, Seki C, Nakao R, Suzuki K, Finnema S, Hirayasu Y, Suhara T, Farde L
    • Journal Title

      J Nucl Med

      Volume : Vol.50 Pages : 703-710

    • URL
      http://jnm.snmjournals.org/content/50/5/703.long
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] No regional difference in dopamine D2 receptor occupancy by the second-generation antipsychotic drug risperidone in humans : a positron emission tomography study2009

    • Author(s)
      Ito H, Arakawa R, Takahashi H, Takano H, Okumura M, Otsuka T, Ikoma Y, Shidahara M, Suhara T
    • Journal Title

      Int J Neuropsychopharmacol

      Volume : Vol.12 Pages : 667-675

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Regional dopamine synthesis in patients with schizophrenia using L-[β-^<11> C] DOPA PET2009

    • Author(s)
      Nozaki S, Kato M, Takano H, Ito H, Takahashi H, Arakawa R, Okumura M, Fujimura Y, Matsumoto R, Ota M, Takano A, Otsuka A, Yasuno F, Okubo Y, Kashima H, Suhara T
    • Journal Title

      Schizophr Res

      Volume : Vol.108 Pages : 78-84

    • URL
      http://www.sciencedirect.com/science/article/pii/S092099640800515X
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Increase in thalamic binding of [^<11>C]PE2I in patients with schizophrenia : a positron emission tomography study of dopamine transporter2009

    • Author(s)
      Arakawa R, Ichimiya T, Ito H, Takano A, Okumura M, Takahashi H, Takano H, Yasuno F, Kato M, Okubo Y, Suhara T.
    • Journal Title

      J Psychiatr Res 43

      Pages : 1219-1223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with L-[β-^<11>C]DOPA : a stabilizing effect for dopaminergic neurotransmission?2009

    • Author(s)
      Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Kodaka F, Okumura M, Otsuka T, Suhara T.
    • Journal Title

      J Neurosci 29

      Pages : 13730-13734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Regional dopamine synthesis in patients with schizophrenia using L-[β-^<11>C]DOPA PET2009

    • Author(s)
      Nozaki S, Kato M, Takano H, Ito H, Takahashi H, Arakawa R, Okumura M, Fujimura Y, Matsumoto R, Ota M, Takano A, Otsuka A, Yasuno F, Okubo Y, Kashima H, Suhara T.
    • Journal Title

      Schizophr Res 108

      Pages : 78-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Quantitative PET analysis of the dopamine D_2 receptor agonist radiolig and ^<11>C-(R)-2-CH_3O-N-n-propylnorapomorphine in the human brain2009

    • Author(s)
      Otsuka T, Ito H, Halldin C, Takahashi H, Takano H, Arakawa R, Okumura M, Kodaka F, Miyoshi M, Sekine M, Seki C, Nakao R, Suzuki K, Finnema S, Hirayasu Y, Suhara T, Farde L.
    • Journal Title

      J Nucl Med 50

      Pages : 703-710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] No regional difference in dopamine D_2 receptor occupancy by the second-generation antipsychotic drug risperidone in humans : a positron emission tomography study2009

    • Author(s)
      Ito H, Arakawa R, Takahashi H, Takano H, Okumura M, Otsuka T, Ikoma Y, Shidahara M, Suhara T.
    • Journal Title

      Int J Neuropsychopharmacol 12

      Pages : 667-675

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Journal Article] Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with ^<11>C-AC-52162009

    • Author(s)
      Miyoshi M, Ito H, Arakawa R, Takahashi H, Takano H, Higuchi M, Okumura M, Otsuka T, Kodaka F, Sekine M, Sasaki T, Fujie S, Seki C, Maeda J, Nakao R, Zhang MR, Fukumura T, Matsumoto M, Suhara T.
    • Journal Title

      J Nucl Med 50

      Pages : 1095-1101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] Relation between pre-and postsynaptic dopaminergic functions measured by PET : implication of dopaminergic tone.2010

    • Author(s)
      Ito H, Takahashi H, Takano H, Arakawa R, Kodaka F, Suhara T.
    • Organizer
      The Eighth International Symposium on Functional Neuroreceptor Mapping of Living Brain(Neuroreceptor Mapping 2010)
    • Place of Presentation
      Glasgow, UK
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] Relation between pre-and postsynaptic dopaminergic functions measured by PET : implication of dopaminergic tone2010

    • Author(s)
      Ito H, Takahashi H, Takano H, Arakawa R, Kodaka F, Suhara T
    • Organizer
      The Eighth International Symposium on Functional Neuroreceptor Mapping of Living Brain(Neuroreceptor Mapping 2010)
    • Place of Presentation
      Glasgow, UK
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] ドーパミン作動性神経系における前シナプス機能と後シナプス機能の関係2010

    • Author(s)
      伊藤浩、高橋英彦、高野晴成、荒川亮介、小高文聰、須原哲也
    • Organizer
      第50回日本核医学会学術総会
    • Place of Presentation
      さいたま市
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] Effects of second-generation antipsychotic drug on dopamine synthesis in human brain measured by PET with L-[C-11]DOPA2009

    • Author(s)
      Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Kodaka F, Okumura M, Otsuka T, Suhara T.
    • Organizer
      XXIVth International Symposium on Cerebral Blood Flow, Metabolism and Function(BRAIN '09)& IXth International Conference on Quantification of Brain Function with PET(BRAIN PET '09)
    • Place of Presentation
      Chicago, IL, USA
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] Effects of second-generation antipsychotic drug on dopamine synthesis in human brain measured by PET with L-[C-11] DOPA2009

    • Author(s)
      Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Kodaka F, Okumura M, Otsuka T, Suhara T
    • Organizer
      XXIVth International Symposium on Cerebral Blood Flow Metabolism and Function(BRAIN' 09) & IXth International Conference on Quantification of Brain Function with PET(BRAIN PET' 09)
    • Place of Presentation
      Chicago, IL, USA
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] Effects of antipsychotic drug on dopamine synthesis in humans measured by PET with[C-11] DOPA2009

    • Author(s)
      Ito H, Takano H, Takahashi H, Arakawa R, Suhara T
    • Organizer
      The Society of Nuclear Medicine 56st Annual Meeting
    • Place of Presentation
      Toronto, Ontario, Canada
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] Effects of antipsychotic drug on dopamine synthesis in humans measured by PET with[C-11]DOPA2009

    • Author(s)
      伊藤浩, 高野晴成, 高橋英彦, 荒川亮介, 須原哲也
    • Organizer
      The Society of Nuclear Medicine 56st Annual Meeting
    • Place of Presentation
      Toronto, Ontario, Canada
    • Data Source
      KAKENHI-PROJECT-21591587
  • [Presentation] 抗精神病薬による脳内ドーパミン生成能変化の検討2009

    • Author(s)
      伊藤浩、高野晴成、高橋英彦、荒川亮介、小高文聰、須原哲也
    • Organizer
      第49回日本核医学会学術総会
    • Place of Presentation
      旭川市
    • Data Source
      KAKENHI-PROJECT-21591587
  • 1.  ITO Hiroshi (20360357)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 38results
  • 2.  TAKANO Harumasa (30348792)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 38results
  • 3.  TAKAHASHI Hidehiko (60415429)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 38results

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