Kanamori Tatsuyuki 金森達之

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KANAMORI Tatsuyuki 金森達之

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Researcher Number	40356192
Other IDs
Affiliation (Current)	2026: 科学警察研究所, 法科学第三部, 室長 2026: 科学警察研究所, 附属鑑定所, 鑑定官
Affiliation (based on the past Project Information) *help	2019 – 2022: 科学警察研究所, 附属鑑定所, 鑑定官 2015 – 2017: 科学警察研究所, 法科学第三部, 主任研究官 2011 – 2013: 科学警察研究所, 法科学第三部, 主任研究官 2007 – 2008: National Research Institute of Police Science, 法科学第三部, 主任研究官
Review Section/Research Field	Principal Investigator Legal medicine / Basic Section 58040:Forensics medicine-related
Keywords	Principal Investigator 代謝 / 肝細胞 / 乱用薬物 / 代謝予測 / ヒト肝細胞 / 三次元培養 / 機器分析 / 代謝物 / アゴニスト活性 / フェンタニル … More / 薬理活性 / ニタゼン / アゴニスト / オピオイド受容体 / オピオイド / 培養肝細胞 / キメラマウス / HepaRG / データベース / iPS細胞 / 危険ドラッグ / スフェロイド / ラット肝細胞 / LC-MS / MS / LC Less

Research Projects
(4 results)
Research Products
(28 results)

Study on the metabolism of new synthetic opioids and evaluation of the pharmacological effects of their metabolitesPrincipal Investigator
- Principal Investigator
  
  KANAMORI Tatsuyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  National Research Institute of Police Science
Drug metabolism study using newly developed human hepatocytes and establishment of a database of drug metabolitesPrincipal Investigator
- Principal Investigator
  
  Kanamori Tatsuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science
Development of an in vitro model system for drug metabolism studies with human hepatocytePrincipal Investigator
- Principal Investigator
  
  KANAMORI Tatsuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science
Establishment of a model system for drug metabolism study by human hepatocyte culturePrincipal Investigator
- Principal Investigator
  
  KANAMORI Tatsuyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  National Research Institute of Police Science

All 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2009 Other

All Journal Article Presentation

[Journal Article] Analysis of highly potent synthetic opioid nitazene analogs and their positional isomers2022
- Author(s)
  Kanamori Tatsuyuki、Okada Yuki、Segawa Hiroki、Yamamuro Tadashi、Kuwayama Kenji、Tsujikawa Kenji、Iwata Yuko T.
- Journal Title
  
  Drug Testing and Analysis
  
  Volume: 15 Issue: 4 Pages: 449-457
- DOI
  10.1002/dta.3415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Evaluation of Agonistic Activity of Fluorinated and Nonfluorinated Fentanyl Analogs on μ-Opioid Receptor Using a Cell-Based Assay System2021
- Author(s)
  Kanamori, T., Okada, Y., Segawa, H., Yamamuro, T., Kuwayama, K., Tsujikawa, K., Iwata, Y.T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 2 Pages: 159-161
- DOI
  10.1248/bpb.b20-00780
- NAID
  130007979656
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Detection and confirmation of the ring-opened carboxylic acid metabolite of a new synthetic opioid furanylfentanyl2021
- Author(s)
  Kanamori, T., Okada, Y., Segawa, H., Yamamuro, T., Kuwayama, K., Tsujikawa, K., Iwata, Y.T.
- Journal Title
  
  Forensic Toxicol.
  
  Volume: 39 Issue: 1 Pages: 114-122
- DOI
  10.1007/s11419-020-00546-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Agonistic activity of fentanyl analogs and their metabolites on opioid receptors2021
- Author(s)
  Kanamori Tatsuyuki、Okada Yuki、Segawa Hiroki、Yamamuro Tadashi、Kuwayama Kenji、Tsujikawa Kenji、Iwata Yuko T.
- Journal Title
  
  Forensic Toxicology
  
  Volume: 40 Issue: 1 Pages: 156-162
- DOI
  10.1007/s11419-021-00602-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Metabolism of a New Synthetic Opioid Tetrahydrofuranylfentanyl in Fresh Isolated Human Hepatocytes: Detection and Confirmation of Ring-Opened Metabolites2020
- Author(s)
  Tatsuyuki Kanamori, Hiroki Segawa, Tadashi Yamamuro, Kenji Kuwayama, Kenji Tsujikawa, Yuko T Iwata
- Journal Title
  
  Drug Test. Anal.
  
  Volume: 12 Issue: 4 Pages: 439-448
- DOI
  10.1002/dta.2743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Characterization and differentiation of positional isomers of fluoro-fentanyl analogs by a combination of instrumental analyses2019
- Author(s)
  金森達之，岩田祐子，瀬川尋貴，山室匡史，桑山健次，辻川健治，井上博之
- Journal Title
  
  Japanese Journal of Forensic Science and Technology
  
  Volume: 24 Issue: 2 Pages: 123-133
- DOI
  10.3408/jafst.760
- NAID
  130007685681
- ISSN
  1880-1323, 1881-4689
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Metabolism of Butyrylfentanyl in Fresh Human Hepatocytes: Chemical Synthesis of Authentic Metabolite Standards for Definitive Identification2019
- Author(s)
  Tatsuyuki Kanamori, Yuko Togawa Iwata, Hiroki Segawa, Tadashi Yamamuro, Kenji Kuwayama, Kenji Tsujikawa, Hiroyuki Inoue
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 4 Pages: 623-630
- DOI
  10.1248/bpb.b18-00765
- NAID
  130007622119
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10702
[Journal Article] Metabolism of Fentanyl and Acetylfentanyl in Human-Induced Pluripotent Stem Cell-Derived Hepatocytes2018
- Author(s)
  Kanamori T, Togawa Iwata Y, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Inoue H
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 1 Pages: 106-114
- DOI
  10.1248/bpb.b17-00709
- NAID
  130006301300
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08895
[Journal Article] Characterization and Differentiation of Geometric Isomers of 3-methylfentanyl Analogs by Gas Chromatography/Mass Spectrometry, Liquid Chromatography/Mass Spectrometry, and Nuclear Magnetic Resonance Spectroscopy.2017
- Author(s)
  Kanamori T, Iwata YT, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Inoue H
- Journal Title
  
  J Forensic Sci.
  
  Volume: 62 Issue: 6 Pages: 1472-1478
- DOI
  10.1111/1556-4029.13395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08895
[Journal Article] TLC，GC/MSおよびLC/MSによるフェンタニル類18化合物の一斉分析2016
- Author(s)
  金森達之，岩田祐子，辻川健治，桑山健次，山室匡史，瀬川尋貴，井上博之
- Journal Title
  
  日本法科学技術学会誌
  
  Volume: 21 Pages: 139-147
- NAID
  130005166236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08895
[Presentation] Analysis of highly potent synthetic opioid nitazene analogs and their positional isomers2023
- Author(s)
  Tatsuyuki Kanamori, Yuki Okada, Hiroki Segawa, Tadashi Yamamuro, Kenji Kuwayama, Kenji Tsujikawa, Yuko T. Iwata
- Organizer
  PITTCON2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10702
[Presentation] 各種フェンタニル系薬物の代謝物のオピオイドμ受容体に対するアゴニスト活性の評価2021
- Author(s)
  金森達之，岡田侑己，瀬川尋貴，山室匡史，桑山健次，辻川健治，岩田祐子
- Organizer
  日本法中毒学会第40年会
- Data Source
  KAKENHI-PROJECT-19K10702
[Presentation] Metabolism of furanylfentanyl in fresh human hepatocytes: Detection and confirmation of furan ring-opened carboxylic acid metabolite2020
- Author(s)
  Tatsuyuki Kanamori, Yuki Okada, Hiroki Segawa, Tadashi Yamamuro, Kenji Kuwayama, Kenji Tsujikawa, Yuko T Iwata
- Organizer
  AAFS 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10702
[Presentation] セルベースアッセイによるフルオロ-フェンタニル類異性体のオピオイド受容体活性化能の評価2020
- Author(s)
  金森達之，岡田侑己，瀬川尋貴，山室匡史，桑山健次，辻川健治，岩田祐子
- Organizer
  日本法中毒学会第39年会
- Data Source
  KAKENHI-PROJECT-19K10702
[Presentation] 新規オピオイド系薬物テトラヒドロフラニルフェンタニルの代謝2019
- Author(s)
  金森達之，岩田祐子，瀬川尋貴，山室匡史，桑山健次，辻川健治，井上博之
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-19K10702
[Presentation] 新規乱用薬物の代謝研究2018
- Author(s)
  金森達之
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K08895
[Presentation] Metabolism of fentanyl and acetylfentanyl by hepatocytes isolated from a liver-humanized mouse2017
- Author(s)
  Kanamori, T. et al
- Organizer
  14th European ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08895
[Presentation] ヒトiPS細胞由来肝細胞によるフェンタニル類の代謝2017
- Author(s)
  金森達之，岩田祐子，瀬川尋貴，山室匡史，桑山健次，辻川健治，井上博之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-15K08895
[Presentation] ヒト肝細胞キメラマウス由来新鮮ヒト肝細胞によるフェンタニル類の代謝2017
- Author(s)
  金森達之他
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-15K08895
[Presentation] The characterization and differentiation of 21 fentanyl analogues by gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS), and nuclear magnetic resonance (NMR) spectroscopy2017
- Author(s)
  Kanamori, T., Iwata, Y.T., Segawa, H., Yamamuro, T., Kuwayama, K., Tsujikawa, K., Inoue, H.
- Organizer
  AAFS 69th Annual Scientific Meeting
- Place of Presentation
  ニューオリンズ（米国）
- Year and Date
  2017-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08895
[Presentation] Hepatocyte spheroid array kit as a tool for predicting in vivo drug metabolism2014
- Author(s)
  Kanamori, T. et al.
- Organizer
  PITTCON
- Place of Presentation
  シカゴ(アメリカ)
- Year and Date
  2014-03-05
- Data Source
  KAKENHI-PROJECT-23590866
[Presentation] 肝細胞スフェロイドアレイ培養キットの新規乱用薬物代謝予測への応用2013
- Author(s)
  金森達之他
- Organizer
  日本法中毒学会第32年会
- Place of Presentation
  千葉県柏市
- Year and Date
  2013-07-05
- Data Source
  KAKENHI-PROJECT-23590866
[Presentation] In vitro metabolism study of designer drugs using a hepatocyte spheroid array kit2013
- Author(s)
  Kanamori, T. et al.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  トロント(カナダ)
- Year and Date
  2013-10-01
- Data Source
  KAKENHI-PROJECT-23590866
[Presentation] 三次元培養肝細胞による新規乱用薬物の代謝2009
- Author(s)
  金森達之、桑山健次、辻川健治、宮口一、岩田祐子、井上博之
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都市
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19790453
[Presentation] 三次元培養肝細胞による新規乱用薬物の代謝2009
- Author(s)
  金森達之、桑山健次、辻川健治、宮口一、岩田祐子、井上博之
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都市
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19790453
[Presentation] Hepatocyte spheroid array kit as a tool for predicting in vivo drug metabolism
- Author(s)
  Kanamori, T., Yamamuro, T., Kuwayama, K., Tsujikawa, K., Iwata, Y.T., Inoue, H.
- Organizer
  PITTCON 2014
- Place of Presentation
  シカゴ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23590866
[Presentation] In vitro metabolism study of designer drugs using a hepatocyte spheroid array kit
- Author(s)
  Kanamori, T., Yamamuro, T., Kuwayama, K., Tsujikawa, K., Iwata, Y.T., Inoue, H.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  トロント（カナダ）
- Data Source
  KAKENHI-PROJECT-23590866
[Presentation] 肝細胞スフェロイドアレイ培養キットの新規乱用薬物代謝予測への応用
- Author(s)
  金森達之，桑山健次，辻川健治，岩田祐子，井上博之
- Organizer
  日本法中毒学会第32年会
- Place of Presentation
  千葉県柏市
- Data Source
  KAKENHI-PROJECT-23590866

Kanamori Tatsuyuki 金森 達之

KANAMORI Tatsuyuki 金森 達之

Research Projects

Research Products

Study on the metabolism of new synthetic opioids and evaluation of the pharmacological effects of their metabolitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug metabolism study using newly developed human hepatocytes and establishment of a database of drug metabolitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an in vitro model system for drug metabolism studies with human hepatocytePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a model system for drug metabolism study by human hepatocyte culturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of highly potent synthetic opioid nitazene analogs and their positional isomers2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of Agonistic Activity of Fluorinated and Nonfluorinated Fentanyl Analogs on μ-Opioid Receptor Using a Cell-Based Assay System2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Detection and confirmation of the ring-opened carboxylic acid metabolite of a new synthetic opioid furanylfentanyl2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Agonistic activity of fentanyl analogs and their metabolites on opioid receptors2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolism of a New Synthetic Opioid Tetrahydrofuranylfentanyl in Fresh Isolated Human Hepatocytes: Detection and Confirmation of Ring-Opened Metabolites2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization and differentiation of positional isomers of fluoro-fentanyl analogs by a combination of instrumental analyses2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Metabolism of Butyrylfentanyl in Fresh Human Hepatocytes: Chemical Synthesis of Authentic Metabolite Standards for Definitive Identification2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Metabolism of Fentanyl and Acetylfentanyl in Human-Induced Pluripotent Stem Cell-Derived Hepatocytes2018

Author(s)

Journal Title

DOI

NAID

ISSN

Kanamori Tatsuyuki 金森達之

KANAMORI Tatsuyuki 金森達之