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Hanamura Kenji  花村 健次

… Alternative Names

HANAMURA Kenji  花村 健次

花村 建次  ハナムラ ケンジ

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Researcher Number 40361365
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-2244-648X
Affiliation (Current) 2026: 新潟医療福祉大学, 医療技術学部, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 新潟医療福祉大学, 医療技術学部, 教授
2022: 群馬大学, 大学院医学系研究科, 准教授
2017 – 2020: 群馬大学, 大学院医学系研究科, 准教授
2016: 群馬大学, 大学院医学系研究科, 助教
2015: 群馬大学, 医学(系)研究科(研究院), 助教
2010 – 2011: 群馬大学, 大学院・医学系研究科, 助教
2004 – 2006: 群馬大学, 大学院・医学系研究科, 助手
Review Section/Research Field
Principal Investigator
Basic Section 63020:Radiation influence-related / Basic Section 43030:Functional biochemistry-related / Neurochemistry/Neuropharmacology
Except Principal Investigator
Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology
Keywords
Principal Investigator
シナプス / 海馬 / 神経新生 / 放射線 / 疼痛 / 神経発達障害 / タンパク質間相互作用 / FN3 / 細胞外リン酸化 / 超解像STED顕微鏡 … More / 発達障害 / シナプスタンパク質 / 発達障害関連分子 / アクチン結合タンパク質 / アクチン細胞骨格 / シナプス機能異常 / 加齢脳 / 神経活動依存性 / in vivo imaging / NMDA受容体 / ドレブリン / 2光子励起レーザー顕微鏡 / 樹状突起スパイン … More
Except Principal Investigator
ドレブリン / アクチン / 生体に光子顕微鏡観察 / 超解像顕微鏡観察 / 神経細胞培養 / PSD-95 / 動態 / スパイン / 海馬 / コフィリン / アクチン細胞骨格 / 分子動態解析 / 樹状突起スパイン / 超解像顕微鏡 / シナプス可塑性 / アクチン線維 / ライブイメージング / 超微小形態 / 培養 / アルツハイマー病 / シナプス / microtubule / axonal growth / actin-binding proteins / immunofluorescence staining / hippocampal neuronal culture / growthcone / actin / 微小管 / 軸索成長 / アクチン結合蛋白 / 免疫蛍光染色 / 海馬初代培養神経細胞 / 成長円錐 / 脳・神経 / 可視化 / 成体神経新生 / 発生・分化 / 神経科学 / ダブルコルチン / 神経細胞移動 / 放射線 / 成熟脳神経細胞分化 Less
  • Research Projects

    (6 results)
  • Research Products

    (77 results)
  • Co-Researchers

    (14 People)
  •  成体海馬の神経新生の傷害を介した放射線による鎮痛作用を担うメカニズムの解明Principal Investigator

    • Principal Investigator
      花村 健次
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63020:Radiation influence-related
    • Research Institution
      Niigata University of Health and Welfare
  •  FN3-containing molecules associated with neurodevelopmental diseases: tyrosine phosphorylation in extracellular region and functionPrincipal Investigator

    • Principal Investigator
      HANAMURA Kenji
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Niigata University of Health and Welfare
      Gunma University
  •  Actin-based model of synaptic plasticity

    • Principal Investigator
      Shirao Tomoaki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gunma University
  •  Analysis of activity-dependent dynamics of NMDA receptors in mice with age-dependent synaptic dysfunctionPrincipal Investigator

    • Principal Investigator
      Hanamura Kenji
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gunma University
  •  Mapping of the developmental stages of neurons in the brain using the radiosensitivity as an index.

    • Principal Investigator
      SHIRAO Tomoaki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gunma University
  •  Role of actin cytoskeleton in the axonal growthcone during brain development

    • Principal Investigator
      SHIRAO Tomoaki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Gunma University

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2011 2010 2006 2005 Other

All Journal Article Presentation Book

  • [Book] iPS細胞の安全・高品質な作製技術2016

    • Author(s)
      花村健次、白尾智明
    • Total Pages
      494
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Journal Article] Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity2024

    • Author(s)
      Altas B, Rhee HJ, Ju A, Cruces-Sol H, Karaca S, Winchenbach J, Kaplan Arabaci O, Schwark M, Ambrozkiewicz M, Lee C, Spieth L, Wieser G, Majoul I, Hassan M, Goel R, Wojcik S, Koganezawa N, Hanamura K, Rotin D, Pichler A, Mitkovski M, de Hoz L, Poulopoulos A, Urlaub H, Jahn O, Saher G, Brose N, Rhee JS, and Kawabe H
    • Journal Title

      Journal of Cell Biology

      Volume: 223 Issue: 1

    • DOI

      10.1083/jcb.201902050

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07864, KAKENHI-PUBLICLY-22H05526, KAKENHI-PROJECT-20K06536
  • [Journal Article] Impacts of methotrexate on survival, dendrite development, and synapse formation of cortical neurons2023

    • Author(s)
      Mai Yamamura, Kenji Hanamura, Noriko Koganezawa, Senami Furubayashi, Tomoaki Shirao, Hiroshi Kawabe.
    • Journal Title

      Genes to Cells

      Volume: 28 Issue: 8 Pages: 563-572

    • DOI

      10.1111/gtc.13035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07864, KAKENHI-PUBLICLY-22H05526, KAKENHI-PROJECT-20K06536
  • [Journal Article] The murine ortholog of Kaufman oculocerebrofacial syndrome gene Ube3b is crucial for the maintenance of the excitatory synapses in the young adult stage2023

    • Author(s)
      Saki Katsube, Noriko Koganezawa, Kenji Hanamura, Katherine J. Cuthill, Victor Tarabykin, Mateusz C. Ambrozkiewicz, Hiroshi Kawabe.
    • Journal Title

      Neuroscience Letters

      Volume: 797 Pages: 137059-137059

    • DOI

      10.1016/j.neulet.2023.137059

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07864, KAKENHI-PUBLICLY-22H05526, KAKENHI-PROJECT-20K06536
  • [Journal Article] Phldb2 is essential for regulating hippocampal dendritic spine morphology through drebrin in an adult-type isoform-specific manner.2022

    • Author(s)
      Xie MJ, Yagi H, Iguchi T, Yamazaki H, Hanamura K, Matsuzaki H, Shirao T, Sato M.
    • Journal Title

      Neurosci. Res.

      Volume: 185 Pages: 1-1

    • DOI

      10.1016/j.neures.2022.09.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06752, KAKENHI-PROJECT-22K06465, KAKENHI-PROJECT-20H03414, KAKENHI-PROJECT-22H00492, KAKENHI-PROJECT-20K06536
  • [Journal Article] Synthetic torpor protects rats from exposure to accelerated heavy ions.2022

    • Author(s)
      Anggraeini Puspitasari, Fabio Squarcio, Martina Quartieri, Cristina Totis, Timna Hitrec, Akihisa Takahashi, Yukari Yoshida, Kenji Hanamura, Tomoko Yako, Matteo Cerri, Palma Simoniello, Marco Durante, Walter Tinganelli
    • Journal Title

      Scientific reports

      Volume: 12 Issue: 1 Pages: 16405-16405

    • DOI

      10.1038/s41598-022-20382-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08044, KAKENHI-PROJECT-20K06536
  • [Journal Article] Hibernation as a Tool for Radiation Protection in Space Exploration2021

    • Author(s)
      A Puspitasari, M Cerri, A Takahashi, Y Yoshida, K Hanamura, W Tinganelli
    • Journal Title

      Life (Basel)

      Volume: 11 Issue: 1 Pages: 54-54

    • DOI

      10.3390/life11010054

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08044, KAKENHI-PROJECT-20K06536
  • [Journal Article] PKN1 promotes synapse maturation by inhibiting mGluR-dependent silencing through neuronal glutamate transporter activation2020

    • Author(s)
      Yasuda Hiroki、Yamamoto Hikaru、Hanamura Kenji、Mehruba Mona、Kawamata Toshio、Morisaki Hiromi、Miyamoto Masaaki、Takada Shinji、Shirao Tomoaki、Ono Yoshitaka、Mukai Hideyuki
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 710-710

    • DOI

      10.1038/s42003-020-01435-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06516, KAKENHI-PROJECT-18H02454, KAKENHI-PROJECT-20K06536
  • [Journal Article] Soy Isoflavones Accelerate Glial Cell Migration via GPER-Mediated Signal Transduction Pathway2020

    • Author(s)
      Ariyani Winda、Miyazaki Wataru、Amano Izuki、Hanamura Kenji、Shirao Tomoaki、Koibuchi Noriyuki
    • Journal Title

      Frontiers in Endocrinology

      Volume: 11 Pages: 554941-554941

    • DOI

      10.3389/fendo.2020.554941

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H03379, KAKENHI-PROJECT-18J23449, KAKENHI-PROJECT-20K06536
  • [Journal Article] Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis2020

    • Author(s)
      Dombroski TCD, Peixoto-Santos JE, Maciel K, Baqui MMA, Velasco TR, Sakamoto AC, Assirati JA, Carlotti CG, Machado HR, Sousa GK, Hanamura K, Leite JP, Costa da Costa J, Palmini AL, Paglioli E, Neder L, Spreafico R, Shirao T, Garbelli R, Martins AR.
    • Journal Title

      Epilepsia

      Volume: 61 Issue: 8 Pages: 1581-1594

    • DOI

      10.1111/epi.16595

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Journal Article] Assessment of NMDA receptor inhibition of phencyclidine analogues using a high-throughput drebrin immunocytochemical assay2019

    • Author(s)
      Mitsuoka Toshinari、Hanamura Kenji、Koganezawa Noriko、Kikura-Hanajiri Ruri、Sekino Yuko、Shirao Tomoaki
    • Journal Title

      Journal of Pharmacological and Toxicological Methods

      Volume: 99 Pages: 106583-106583

    • DOI

      10.1016/j.vascn.2019.106583

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08010, KAKENHI-PROJECT-17H03557
  • [Journal Article] High-content imaging analysis for detecting the loss of drebrin clusters along dendrites in cultured hippocampal neurons2019

    • Author(s)
      Hanamura Kenji、Koganezawa Noriko、Kamiyama Kazumi、Tanaka Natsume、Oka Takero、Yamamura Mai、Sekino Yuko、Shirao Tomoaki
    • Journal Title

      Journal of Pharmacological and Toxicological Methods

      Volume: 99 Pages: 106607-106607

    • DOI

      10.1016/j.vascn.2019.106607

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08010, KAKENHI-PROJECT-17H03557
  • [Journal Article] Isoform-dependent Regulation of Drebrin Dynamics in Dendritic Spines2018

    • Author(s)
      Hanamura Kenji、Kamata Yousuke、Yamazaki Hiroyuki、Kojima Nobuhiko、Shirao Tomoaki
    • Journal Title

      Neuroscience

      Volume: 379 Pages: 67-76

    • DOI

      10.1016/j.neuroscience.2018.02.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Journal Article] Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction2018

    • Author(s)
      Yasuda Hiroki、Kojima Nobuhiko、Hanamura Kenji、Yamazaki Hiroyuki、Sakimura Kenji、Shirao Tomoaki
    • Journal Title

      Frontiers in Cellular Neuroscience

      Volume: 12 Pages: 330-330

    • DOI

      10.3389/fncel.2018.00330

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06516, KAKENHI-PROJECT-17H03557
  • [Journal Article] N-methyl-D-aspartate Receptor Mediates X-irradiation-induced Drebrin Decrease in Hippocampus2018

    • Author(s)
      Miao S, Koganezawa N, Hanamura K, Puspitasari A, Shirao T.
    • Journal Title

      The Kitakanto Medical Journal

      Volume: 68 Issue: 2 Pages: 111-115

    • DOI

      10.2974/kmj.68.111

    • NAID

      130007393985

    • ISSN
      1343-2826, 1881-1191
    • Year and Date
      2018-05-01
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K18376, KAKENHI-PROJECT-17K16424, KAKENHI-PROJECT-17H03557
  • [Journal Article] Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain2017

    • Author(s)
      Hanamura Kenji、Washburn Halley R.、Sheffler-Collins Sean I.、Xia Nan L.、Henderson Nathan、Tillu Dipti V.、Hassler Shayne、Spellman Daniel S.、Zhang Guoan、Neubert Thomas A.、Price Theodore J.、Dalva Matthew B.
    • Journal Title

      PLOS Biology

      Volume: 15 Issue: 7 Pages: e2002457-e2002457

    • DOI

      10.1371/journal.pbio.2002457

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Journal Article] Progress in applications of iPSC-derived neurons for evaluation of drugs2017

    • Author(s)
      Koganezawa N, Hanamura K, Shirao T.
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 149 Issue: 3 Pages: 104-109

    • DOI

      10.1254/fpj.149.104

    • NAID

      130005403859

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H06078, KAKENHI-PROJECT-17H03557
  • [Journal Article] Drebrin in Alzheimer’s Disease2017

    • Author(s)
      Ishizuka Yuta、Hanamura Kenji
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 1006 Pages: 203-223

    • DOI

      10.1007/978-4-431-56550-5_12

    • ISBN
      9784431565482, 9784431565505
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Journal Article] The role of drebrin in dendritic spines2017

    • Author(s)
      Koganezawa N, Hanamura K, Sekino Y, Shirao T
    • Journal Title

      Mol. Cell. Neurosci.

      Volume: - Pages: 85-92

    • DOI

      10.1016/j.mcn.2017.01.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14344, KAKENHI-PROJECT-16K18376, KAKENHI-PROJECT-15H06078, KAKENHI-PROJECT-17H03557
  • [Journal Article] Drebrin in Neuronal Migration and Axonal Growth2017

    • Author(s)
      Hanamura Kenji
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 1006 Pages: 141-155

    • DOI

      10.1007/978-4-431-56550-5_9

    • ISBN
      9784431565482, 9784431565505
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Journal Article] The role of drebrinin neurons2017

    • Author(s)
      Shirao T, Hanamura K, Koganezawa N, Ishizuka Y, Yamazaki H, Sekino Y.
    • Journal Title

      J. Neurochem.

      Volume: - Issue: 6 Pages: 819-834

    • DOI

      10.1111/jnc.13988

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14344, KAKENHI-PROJECT-16K18376, KAKENHI-PROJECT-15H06078, KAKENHI-PROJECT-17H03557, KAKENHI-PROJECT-26430063
  • [Journal Article] Localization of Drebrin: Light Microscopy Study2017

    • Author(s)
      Shirao Tomoaki、Koganezawa Noriko、Yamazaki Hiroyuki、Hanamura Kenji、Imamura Kazuyuki
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 1006 Pages: 105-118

    • DOI

      10.1007/978-4-431-56550-5_7

    • ISBN
      9784431565482, 9784431565505
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Journal Article] Allopregnanolone increases mature excitatory synapses along dendrites via protein kinase A signaling2015

    • Author(s)
      Shimizu H, Ishizuka Y, Yamazaki H, Shirao T.
    • Journal Title

      Neuroscience

      Volume: 305 Pages: 139-145

    • DOI

      10.1016/j.neuroscience.2016.03.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14344, KAKENHI-PROJECT-15H06078, KAKENHI-PROJECT-26430076, KAKENHI-PROJECT-26430003
  • [Journal Article] Evidence for cell density affecting C2C12 myogenesis2011

    • Author(s)
      Tanaka K, Sato K, Yoshida T, Fukuda T, Hanamura K, Kojima N, Shirao T, Yanagawa T, Watanabe H
    • Journal Title

      possible regulation of myogenesis by cell-cell communication

      Volume: 44 Pages: 968-977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Journal Article] Low accumulation of drebrin at glutamatergic postsynaptic sites on GABAergic neurons2010

    • Author(s)
      Hanamura, K, Mizui T, Kakizaki T, Roppongi TR, Yamazaki H, Yanagawa Y, Shirao T
    • Journal Title

      Neuroscience

      Volume: 169 Pages: 1489-1500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Journal Article] Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood2010

    • Author(s)
      Kojima N, Hanamura K, Yamazaki H, Ikeda T, Itohara S, Shirao T
    • Journal Title

      Neuroscience

      Volume: 165 Pages: 138-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Journal Article] Activation of N-methyl-D-aspartate receptor induces a shift of drebrin distribution : disappearance from dendritic spines and appearance in dendritic shafts2006

    • Author(s)
      Sekino, Y., Tanaka, S., Hanamura, K., Yamazaki, H., Sasagawa, Y., Xue Y., Hayashi, K., Shirao, T.
    • Journal Title

      MoL Cell. Neurosci 31

      Pages: 493-504

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300117
  • [Journal Article] Drebrin A is a Postsynaptic Protein that Localizes in vivo to the Submembranous Surface of Dendritic Sites Forming Excitatory Synapses2005

    • Author(s)
      Aoki, C., Sekino, Y., Hanamura, K., Fujisawa, S., Mahadomrongkul, V., Ren, Y., Shirao, T.
    • Journal Title

      J. Comp. Neurol. 483

      Pages: 383-402

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300117
  • [Journal Article] Expression of drebrin E in migrating neuroblasts in adult rat brain : coincidence between drebrin E disappearance from cell body and cessation of migration

    • Author(s)
      Song M, Kojima N, Hanamura K, Sekino Y, Inoue KH, Mikuni M, Shirao T
    • Journal Title

      Neuroscience. (印刷中)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300117
  • [Presentation] X-ray irradiation in developing mice leads to weight loss, transient alopecia, and pelvic and femoral bone alterations2025

    • Author(s)
      Kenji Hanamura, Mao Yoshino, Chikaho Hosoi, Kenshin Matsui, Toa Matsui, Nobukiyo Yoshida
    • Organizer
      The 14th Annual Meeting of The International Society of Radiation Neurobiology (ISRN2025)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Presentation] X-ray irradiation in developing mice leads to weight loss, transient alopecia, and pelvic and femoral bone alterations2025

    • Author(s)
      Kenji Hanamura, Mao Yoshino, Chikaho Hosoi, Kenshin Matsui, Toa Matsui, Nobukiyo Yoshida
    • Organizer
      The 14th Annual Meeting of The International Society of Radiation Neurobiology (ISRN2025)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K15294
  • [Presentation] Closed, pumpless microphysiological system with unidirectional flow for studying radiation-induced bystander effects in cultured neurons.2024

    • Author(s)
      Kenji Hanamura, Hidetaka Ueno, Yuri Aoki, Mai Yamamura, Tomoaki Shirao and Takaaki Suzuki
    • Organizer
      The 13th International Society of Radiation Neurobiology Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Presentation] 放射線が神経細胞の発達に与える影響のハイコンテントイメージングシステムを用いた解析2023

    • Author(s)
      花村健次、白尾智明
    • Organizer
      第23回 新潟医療福祉学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Presentation] 3D-STED顕微鏡による自閉症スペクトラム症モデルマウスの興奮性シナプス数の解析2022

    • Author(s)
      中村 友哉、花村 健次、堀 啓、星野 幹雄、川辺 浩志
    • Organizer
      第96回日本薬理学会年会/第43回日本臨床薬理学会学術年会
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Presentation] カウフマン症候群原因遺伝子であるUbe3bは若年成人期のシナプス数維持に重要である2022

    • Author(s)
      勝部 早紀、小金澤 紀子、花村 健次、Katherine J. Cuthill、Mateusz C. Ambrozkiewicz、川辺 浩志
    • Organizer
      第96回日本薬理学会年会/第43回日本臨床薬理学会学術年会
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Presentation] DEVELOPMENT OF CLOSED AND PUMPLESS PLATFORM FOR CO-CULTURE IN MINIMALIZED SPACE2020

    • Author(s)
      Hidetaka Ueno, Yuri Aoki, Kenji Hanamura, Mai Yamamura, Tomoaki Shirao, and Takaaki Suzuki
    • Organizer
      The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06536
  • [Presentation] High-throughput imaging analysis using cultured neurons for detecting phencyclidine-like substances2019

    • Author(s)
      Hanamura K, MitsuokaT, Kikura-Hanajiri R, Sekino Y, Shirao T
    • Organizer
      9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-content imaging analysis of synaptic status, dendrite length and neuron number in cultured neurons for detecting adverse effects of toxic substances2019

    • Author(s)
      Kenji Hanamura, Anggraeini Puspitasari, Noriko Koganezawa, Tomoaki Shirao
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] LTD is regulated by drebrin isoforms conversion likely due to the difference in the isoform dynamics2019

    • Author(s)
      Tomoaki Shirao, Kenji Hanamura, Nobuhiko Kojima, Hiroki Yasuda, Yuko Sekino
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] LTD is regulated by drebrin isoforms conversion likely due to the difference in the isoform dynamics2019

    • Author(s)
      Tomoaki Shirao, Kenji Hanamura, Nobuhiko Kojima, Hiroki Yasuda, Yuko Sekino
    • Organizer
      9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Establishment of high-throughput system for efficiently detecting New Psychoactive Substances to inhibit the activity of NMDA receptor2019

    • Author(s)
      Toshinari Mitsuoka, Kenji Hanamura, Ruri Kikura-Hanajiri, Yuko Sekino, Tomoaki Shirao.
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-throughput imaging analysis using cultured neurons for detecting phencyclidine-like substances2019

    • Author(s)
      Kenji Hanamura, Toshinari Mitsuoka, Ruri Kikura-Hanajiri, Yuko Sekino, Tomoaki Shirao
    • Organizer
      The 9th Federation of the Asian and Oceanian Physiological Societies Congress
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] X- irradiation of immature developing neurons causes delayed synaptopathy and decreases the number of bystander neurons2019

    • Author(s)
      Anggraeini Puspitasari, Hiroyuki Yamazaki, Kenji Hanamura, Kathryn D Held, Tomoaki Shirao
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Development of drebrin nanobody as a novel tool for in vitro and in vivo research2019

    • Author(s)
      Hiroyuki Yamazaki, Kenji Hanamura, Narutoshi Tsukahara, Banri Segawa, Akikazu Murakami, Tomoaki Shirao
    • Organizer
      第42回日本神経科学大会・第62回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] 培養神経細胞の樹状突起に沿ったドレブリンクラスターに対する神経伝達物質や化合物等の効果を評価するハイコンテントイメージング解析法の開発2019

    • Author(s)
      369.山村真伊、花村健次、白尾智明
    • Organizer
      北関東医学会総会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-throughput imaging analysis for detecting the effects of irradiation on synaptic status2019

    • Author(s)
      Kenji Hanamura, Shuchuan Miao, Natsume Tanaka, Noriko Koganezawa, Anggraeini Puspitasari, Hidetaka Ueno, Takaaki Suzuki, Tomoaki Shirao
    • Organizer
      The 9th International Society of Radiation Neurobiology Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] The fate of immature neurons and immature bystander neurons following X-irradiation2019

    • Author(s)
      Anggraeini Puspitasari, Hiroyuki Yamazaki, Kenji Hanamura, Tomoaki Shirao, Kathryn D Held
    • Organizer
      The International Congress of Radiation Research (ICRR)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Establishment of a high-throughput drebrin immunocytochemical assay for NMDA receptor inhibition of new psychoactive substances2019

    • Author(s)
      Toshinari Mitsuoka, Kenji Hanamura, Noriko Koganezawa, Ruri Kikura-Hanajiri, Tomoaki Shirao, Yuko Sekino
    • Organizer
      6th Congress of Asian college of Neuropsychopharmacology (AsCNP)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] NMDA型グルタミン酸受容体阻害作用を持つ危険ドラッグの検出方法の開発研究2018

    • Author(s)
      光岡俊成,花村健次,関野祐子,花尻(木倉)瑠璃,白尾智明,池谷裕二
    • Organizer
      第18回東京大学 生命科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] NMDA receptor mediates X-irradiation-induced drebrin decrease in hippocampal dentate gyrus2018

    • Author(s)
      Shuchuan Miao, Noriko Koganezawa, Kenji Hanamura, Tomoaki Shirao
    • Organizer
      The 8th International Society of Radiation Neurobiology Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-content imaging analysis of the status of synapses using drebrin in cultured neurons2018

    • Author(s)
      Kenji Hanamura, Yuko Sekino and Tomoaki Shirao
    • Organizer
      18th World Coongress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High content imaging analysis of drebrin clusters along dendrites regulated by NMDA receptor activity2018

    • Author(s)
      Kenji Hanamura, Toshinari Mitsuoka, Yuko Sekino, Tomoaki Shirao
    • Organizer
      第95回日本生理学会大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Drebrins critically regulate mGluR- and NMDAR-dependent LTD induction2018

    • Author(s)
      Hiroyuki Yasuda, Nobuhiko Kojima, Hiroyuki Yamazaki, Kenji Hanamura, Tomoaki Shirao
    • Organizer
      第95回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-content Imaging Analysis For Detecting The Status Of Synapses In Cultured Hippocampal Neurons2018

    • Author(s)
      Kenji Hanamura, Noriko Koganezawa, Yuko Sekino, Tomoaki Shirao
    • Organizer
      Society of Toxicology 57th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-content imaging analysis for detecting the status of synapses in cultured hippocampal neurons2018

    • Author(s)
      Kenji Hanamura, Noriko Koganezawa, Yuko Sekino, Tomoaki Shirao
    • Organizer
      日本安全性薬理研究会第9回学術年会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] High-content imaging analysis of synaptic status in cultured neurons : evaluation of activity-dependent regulation of drebrin clusters along dendrites by NMDA receptors2018

    • Author(s)
      Kenji Hanamura, Noriko Koganezawa, Yuko Sekino, Tomoaki Shirao
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Isoform-dependent regulation of drebrin dynamics in dendritic spines2017

    • Author(s)
      Kenji Hanamura, Tomoaki Shirao
    • Organizer
      第60回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] ベンゾジアゼピン系薬剤の培養海馬神経細胞シナプス数に対する作用―医薬品の中枢神経系有害反応予測のための新規 in vitro 評価系確立の試み2017

    • Author(s)
      清水英雄、小針彩奈、須知由未子、関口敬洋、花村健次、白尾智明、田辺光男、関野祐子、佐藤薫
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] High-content imaging analysis of glutamatergic synapses using primary cultured neurons2017

    • Author(s)
      Takero Oka, Kenji Hanamura, Noriko Koganezawa, Kazumi Kamiyama, Natsume Tanaka, Tomoaki Shirao
    • Organizer
      The 7th International Society of Radiation Neurobiology Conference
    • Place of Presentation
      湯沢(新潟)
    • Year and Date
      2017-02-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] Role of drebrin isoform conversion in synapse formation2017

    • Author(s)
      Tomoaki Shirao, Kenji Hanamura
    • Organizer
      JCS Journal Meeting, Cellular dynamics: membrane-cytoskeleton interface
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Differential changes of drebrin and PSD-95 localization in response to glutamate stimulation2017

    • Author(s)
      Sunchuan Miao, Noriko Koganezawa, Kenji Hanamura, Tomoaki Shirao
    • Organizer
      The 38th World Congress of the International Union of Physiological Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] 培養神経細胞を用いたハイコンテントイメージングによるシナプスの解析2017

    • Author(s)
      岡丈朗、花村健次、白尾智明
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] An imaging assay to analyze primary hippocampal neurons for cellular maturation2017

    • Author(s)
      Tomoaki Shirao, Kenji Hanamura, Noriko Konganezawa, Hiroyuki Yamazaki, Yuko Sekino
    • Organizer
      10th Congress on Alternatives and Animal Use in the Life Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Drebrin plays a role in mGluR5-dependent LTD2017

    • Author(s)
      Tomoaki Shirao, Kenji Hanamura, Hiryoki Yasuda, Yuko Sekino, Nobuhiko Kojima
    • Organizer
      Society for Neuroscience 46th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03557
  • [Presentation] Stable fraction of drebrin in dendritic spines is regulated by the isoform conversion2017

    • Author(s)
      Kenji Hanamura, Tomoaki Shirao.
    • Organizer
      The 7th International Society of Radiation Neurobiology Conference
    • Place of Presentation
      湯沢(新潟)
    • Year and Date
      2017-02-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] シナプスイメージングに基づき医薬品の認知機能影響リスクを予測する in vitro 評価系確立の試み2017

    • Author(s)
      清水英雄、小針彩奈、須知由未子、関口敬洋、花村健次、白尾智明、田辺光男、関野祐子、佐藤薫
    • Organizer
      第59回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2017-09-08
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] 発達期樹状突起スパインのアクチン細胞骨格成熟とその加齢依存的なシナプス可塑性における役割2016

    • Author(s)
      花村健次、児島伸彦、安田浩樹、山﨑博幸、白尾智明
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] スパイン内のドレブリンの安定性は発達期のアイソフォーム変換によりアクチン細胞骨格依存的に増加する2016

    • Author(s)
      花村健次、白尾 智明
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] Quantitative imaging analysis of amyloid beta toxicity using cultured neurons.2016

    • Author(s)
      Tomoaki Shirao, Yuta Ishizuka, Kenji Hanamura, Yasunari Kanda and Yuko Sekino,
    • Organizer
      The 5th Annual Meeting of the American Society for Cellular and Computational Toxicology (ASCCT)
    • Place of Presentation
      Durham, NC, USA
    • Year and Date
      2016-09-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] EphB Extracellular Phosphorylation Controls Pathological Pain and Synaptic Function of NMDA Receptors2015

    • Author(s)
      Hanamura K., Sheffler-Collins S.I., Xia N., Washburn H.R., Tillu D., Hassler S, Spellman D.S., Zhang G., Neubert T.A., Price T.J., Dalva M.B.
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮ソニックシティ(さいたま)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15H06078
  • [Presentation] スパイン内のアイソフォーム特異的なドレブリン動態のアクチン細胞骨格による制御機構2011

    • Author(s)
      鎌田洋輔, 花村健次, 山崎博幸, 白尾智明
    • Organizer
      First annual meeting of International Society of Radiation Neurobiology
    • Place of Presentation
      Maebashi, Japan,群馬大学刀城会館(群馬県)
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Presentation] X ray Irradiation Induces Acute Depolymerization of Axonal and Dendritic Microfilaments in Cultured Neuron2011

    • Author(s)
      Y. Suzuki, M. Hino, K. Shirai, Y. Yoshida, T. Mizui, K. Hanamura, T. Shirao, T. Nakano
    • Organizer
      ASTRO's 53^<rd> Annual Meeting
    • Place of Presentation
      Maiami Beach, FL(マイアミ、アメリカ)
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Presentation] X線照射による脳におけるmTORシグナル及びタンパク質合成の変化2011

    • Author(s)
      石塚佑太, 花村健次, 児島伸彦, 白尾智明, 武井延之
    • Organizer
      First annual meeting of International Radiation Neurobiology
    • Place of Presentation
      Maebashi, Japan,群馬大学刀城会館(群馬県)
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Presentation] Acute effect of X-irradiation on conditioned fear memory2011

    • Author(s)
      Kojima N, Hanamura K, Shirao T
    • Organizer
      First annual meeting of International Society of Radiation Neurobiology
    • Place of Presentation
      Maebashi, Japan,群馬大学刀城会館(群馬県)
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Presentation] Low accumulation of drebrin in the postsynaptic sites of glutamatergic synapses formed on GABAergic neurons2010

    • Author(s)
      花村健次
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Presentation] 海馬ニューロンの樹状突起スパインにおけるドレブリンのアイソフォーム特異的な動態の制御機構2010

    • Author(s)
      花村健次
    • Organizer
      第19回海馬と高次脳機能学会
    • Place of Presentation
      金澤
    • Data Source
      KAKENHI-PROJECT-22650076
  • [Presentation] アクチン結合乞ンパク質ドレブリンのスパイン内動態を制御するメカニズムの解析2010

    • Author(s)
      花村健次
    • Organizer
      第33回日本神経科学大会・第53回日本神経化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22650076
  • 1.  SHIRAO Tomoaki (20171043)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 40 results
  • 2.  KOJIMA Nobuhiko (80215251)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  YAMAZAKI Hiroyuki (10334137)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 4.  SHKINO Yuko (70138866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  TAKATSURU YUSUKE (30446265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  XIE Min-jue
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  YOSHIDA Yukari
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  MIYAZAKI Wataru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  松崎 秀夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  安田 浩樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  向井 秀幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  小金澤 紀子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 13.  石塚 佑太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  鯉淵 典之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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